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stress - induced cardiomyopathy ( scmp ) is a nonischemic reversible cardiomyopathy characterized uniquely by a left ventricular ( lv ) wall motion abnormality termed " apical ballooning " and the prognosis is generally excellent.1)2 ) however , several critical complications are possible .
the formation of lv thromb... | although stress - induced cardiomyopathy ( scmp ) is a reversible disease and the prognosis is usually excellent , several complications can occur and can result in fatal adverse events .
the formation of left ventricular ( lv ) thrombus is one of these critical complications of scmp .
this report describes a case ... |
the current study is a secondary analysis of baseline data from a randomized clinical trial of a school - based intervention for youth at risk for type 2 diabetes ( 12 ) .
seventh grade youth from six schools in a new england city were invited to participate if they had bmi 85th percentile and a family member with di... | objectivethe purpose of this study was to determine the impact of sex and race / ethnicity on metabolic risk and health behaviors in minority youth.research design and methodsa total of 173 seventh graders ( 46% male and 54% female ; 49% hispanic and 51% african american ) with bmi 85th percentile and a family history ... |
a recent article from the group in berlin reports on a retrospective review of observational data comparing their experience using tranexamic acid as an enforced alternative to aprotinin .
their data suggest an increase in morbidity and mortality in the tranexamic acid treated patients .
the first was to cause al... | the withdrawal of marketing approval for aprotinin resulted in more clinicians administering tranexamic acid to patients at increased risk of bleeding and adverse outcome . the latest in a series of retrospective analyses of observational data
is published in critical care and suggests an increase in mortality , when... |
dysregulation of gluconeogenesis is a key pathological feature of type 2 diabetes .
however , the molecular mechanisms underlying the regulation of gluconeogenesis remain unclear .
bhalla et al .
recently reported that cyclin d1 suppresses hepatic gluconeogenesis through cdk4dependent phosphorylation of pgc1alph... | |
spinal cord injury ( sci ) is a damage to the spinal cord that results in the loss of mobility and sensation below the level of injury .
the disorder is characterized according to the amount of functional loss , sensational loss , and inability to stand and walk .
for example there are 12.7 and 59 new cases per mil... | spinal cord injury ( sci ) is damage to spinal cord , which is categorized according to the extent of functional loss , sensation loss and inability of the subjects to stand and walk .
the patients use two transportation systems including orthosis and wheelchair .
it was claimed that standing and walking bring some... |
, there is a loss of electron and formation of ferric molecule , which in turn results in formation of methemoglobin . in healthy individuals too , there is a small proportion of methemoglobin ( 2 - 3% ) .
this disorder is typically seen in three settings : endemic methemoglobinemia ; in individuals of consanguineous... | congenital methemoglobinemia is a rare condition resulting from a deficiency of nicotinamide adenine dinucleotide - cytochrome b5 reductase .
acquired methemoglobinemia may result due to certain drugs , chemicals and food items .
information on epidemiological determinants from india is sparse .
this report descr... |
most symptomatic patients present with postprandial fullness and gastrointestinal hemorrhage ; however , other patients present with an incidental submucosal filling defect on upper gastrointestinal contrast studies or a smooth effacement of gastric mucosa overlying a submucosal mass ( schindler 's sign ) on endoscopy ... | gastric leiomyoma is a relatively rare gastric neoplasm . before the routine use of laparoscopy , various methods of treatment for gastric leiomyoma included open celiotomy with gastric wedge resection , partial gastrectomy , enucleation , and extended gastrectomy with en bloc resection of adjacent organs .
below , w... |
external tooth bleaching is a conservative and well - accepted technique for whitening teeth with surface and intrinsic staining , which is opening up new avenues and becoming much more prevalent in esthetic dentistry .
the idea is that using this technique can effectively make stained teeth whiter through direct app... | objective : to compare the effects of three antioxidants ( sodium ascorbate , sodium ascorbate combined with a surfactant , and catalase ) on the microleakage of composite resin restorations after external tooth bleaching with 10% carbamide peroxide.materials and methods :
buccal cavities were prepared on the surface... |
although clinically recognized metastatic thyroid cancer is rare , data from autopsy show that thyroid metastasis findings range from 1.9% to 24.2% , with the common sources of primary cancer being skin , lung , and breast.1,2 however , of the clinically recognized metastases to the thyroid , more than 50% of the time ... | metastasis to the thyroid gland from distant cancer is rare , and , in some cases , is a diagnostic challenge . here
, we report a case of metastatic renal cell carcinoma of the thyroid gland . a 77-year - old man presented with a neck mass detected about 1 month previously .
he had undergone a right nephrectomy ow... |
the arenaviridae family comprises only one genus formed of 25 species of arenaviruses , as categorized by the ictv , and listed in ( table 1 ) .
a further classification is based on the geography of origin and distribution of the viruses and their hosts : old world arenaviruses ( owa ) and new world arenaviruses ( nw... | the arenaviridae family includes several hemorrhagic fever viruses which are important emerging pathogens .
junn virus , a member of this family , is the etiological agent of argentine hemorrhagic fever ( ahf ) . a collaboration between the governments of argentina and the usa rendered the attenuated junn virus vacci... |
deliberate self - injury or pathological self - mutilation is the deliberate alteration or destruction of the body tissue without conscious suicidal intent .
the diverse behaviors that constitute pathological mutilation have been categorized into the following three basic types : major - infrequent acts that result i... | we report a case of repeated self - injurious behavior .
self injury to the operated eye had resulted in complete loss of vision in one eye .
this case illustrates multiple challenges posed to the treating teams managing the causes and consequences of such self - injurious behaviors . |
percutaneous endoscopic gastrostomy ( peg ) tube placement has been the minimally invasive procedure of choice for enteral access , or decompression , since the early 1980s .
herniation through gastrostomy site is considered an extremely rare complication with only four cases reported .
we present two unusual cases... | highlightstow rare cases of herniation through gastrostomy site.percutaneous endoscopic gastrostomy is the minimally invasive procedure of choice for enteral access or decompression.while it s exceedingly rare , herniation through gastrostomy site is a possible complication that we should be aware of.in our two cases ,... |
this report describes the clinical and parasitological findings in a domestic shorthair cat with isolated thoracic tetrathyridiosis . the cat was a stray from malta that had lived in germany for several years since as an indoor - only cat .
it must be considered that the cat had been infected years previously while i... | case summarythis report describes the clinical and parasitological findings in a domestic shorthair cat with isolated thoracic tetrathyridiosis .
the cat was a stray from malta that had lived in germany for several years since as an indoor - only cat .
therefore , the process of infection remains very unusual . in ... |
patients with cancer cachexia experience loss of weight often accompanied by anorexia and other debilitating symptoms that impact everyday life .
two decades of exploratory investigation of the manifestations , meaning and management of cancer cachexia reveal emotional and social impacts for both patients and their f... | backgroundcancer cachexia has impact on patients and their family members .
patients experience loss of weight often accompanied by anorexia and other debilitating symptoms that have clinical impact and impact everyday life .
the importance of understanding this impact lies in ( 1 ) the alleviation of cachexia - re... |
hyperglycemia is a risk factor for microvascular complications in patients with type 2 diabetes . apart from hyperglycemia
, dyslipidemia also contributes to the risk of developing complications in patients with type 2 diabetes . even the national cholesterol education program
( ncep ) adult treatment panel iii has... | hyperglycemia and hyperlipidemia are both risk factors for the development of various complications in patients with type 2 diabetes mellitus .
colesevelam hydrochloride is a novel agent that can improve both hypercholesterolemia and hyperglycemia in such patients .
it is an orally administered bile acid sequestran... |
colon cancer , however , is generally a disease of the elderly and occurs only rarely during pregnancy .
its symptoms typically include nausea , vomiting , abdominal pain , and altered bowel movements , which commonly overlap with symptoms of normal pregnancy .
therefore , physicians and patients usually attribute ... | introductioncolon cancer in pregnant women is rare and tends to produce unspecific symptoms until advanced stage .
therefore common manifestations during pregnancy must be properly evaluated to avoid delayed diagnosis.presentation of casea 31-year - old pregnant woman presented with nausea , vomiting and obstipation ... |
polymyalgia rheumatica ( pmr ) is relatively common among people who are over 50 years of age .
the combination of persistent pain over multiple joints and muscles of the body , morning stiffness , and elevated erythrocyte sedimentation rate ( esr ) are characteristics of this condition.1 multiple genetic and environ... | polymyalgia rheumatica ( pmr ) is relatively common among the elderly , and is characterized by multiple body aches with an elevated erythrocyte sedimentation rate . even though the etiology of pmr remains unknown , a number of infectious agents
have been suggested to cause pmr . also , there are reports of pmr after... |
spinal artery aneurysms are most commonly associated with high - flow states secondary to either arteriovenous shunting or occlusive disease of larger arteries causing increased flow through spinal arteries recruited as collateral circulation.1)2)4 ) an aneurysm is considered " isolated " when it occurs in the absence ... | rupture of isolated posterior spinal artery ( psa ) aneurysms is a rare cause of subarachnoid hemorrhage ( sah ) that presents unique diagnostic challenges owing to a nuanced clinical presentation . here
, we report on the diagnosis and management of the first known case of an isolated psa aneurysm in the context of ... |
spinal location of a lymphomatous lesion is commonly seen as a metastasis in patients known to have systemic lymphoma .
many authors have described the entity of primary spinal epidural lymphomas ( psel ) , where there is no other evidence of lymphoma in the body other than a solitary lesion in the epidural space .
... | we report a case of lumbar intradural extramedullary lesion in an 11-year - old boy who presented with cauda equina syndrome and acute bladder disturbance .
he underwent emergency surgical resection of the lesion , which was proved to be a lymphoma by histopathology and immunohistochemistry .
he has improved neurol... |
enterococci , an important cause of clinical infections , have emerged as an increasingly important cause of nosocomial infections in the last decades , being now the third to fourth - most prevalent nosocomial pathogen worldwide .
the emergence and spread of resistance to vancomycin as well as other glycopeptide age... | summaryvancomycin - resistant enterococci ( vre ) represent as an immediate threat to public health .
since few active compounds are available for vre infections , rapid identification of these isolates are essential . in the absence of any report on the genetic relatedness of enterococcus faecalis especially vancomy... |
we present a case of postpartum female with hemolysis , elevated hepatic enzymes , low platelets ( hellp ) with deranged renal function , and cerebral venous thrombosis , without a history of hypertension and proteinuria .
plasma exchange therapy was successfully used in reversal of organ dysfunction and resolution o... | the differential diagnosis of life - threatening microangiopathic disorders in a postpartum female includes severe preeclampsia
eclampsia , hemolysis , elevated liver functions tests , low platelets syndrome and thrombotic thrombocytopenic purpura .
there is considerable overlapping in the clinical and laboratory f... |
the chronic prostatitis syndromes and symptomatic benign prostatic hyperplasia ( bph ) are common among aged men and women .
the etiology of prostatitis syndrome remain elusive , it does appear to be associated with a high incidence of voiding dysfunction .
lower urinary tract syndromes ( luts ) are sometimes assoc... | alfuzosin , a selective alpha-1a antagonistis is the most recently approved aaras , with limited cardiac toxicity and exclusively used for lower urinary tract syndromes ( luts ) . in order to reduce pill burden and better patient compliance modified release ( mr ) formulations have been developed .
alfuzosin mr table... |
ubiquitous computing , following the vision of weiser , aims to embed small computer devices into every day objects augmenting them with new functionality , building an environment full of distributed computers .
scenarios for major applications include homecare monitoring [ 4 - 6 ] and assistance for health professi... | in order to provide more effective and personalized healthcare services to patients and healthcare professionals , intelligent active knowledge management and reasoning systems with semantic interoperability are needed .
technological developments have changed ubiquitous healthcare making it more semantically interop... |
there appears to be evidence that aspects of trunk control in the sitting position can be
used as predictors of comprehensive activities of daily living function in patients with
stroke1 .
the following characteristics
of the sitting position in post - stroke hemiparetic patients have been reported : the
stab... | [ purpose ] the purpose of this study was to investigate the relationship between the
ability to perform the sit - to - stand movement and the maximum pelvic anteversion and
retroversion angles of patients .
[ subjects ] thirty - two stroke patients ( 66.77.6 years )
( > 3 months post - stroke ) who were able ... |
mycobacterium kansasii is a slow - growing acid - fast bacillius ( afb ) and belongs to the group of environmental mycobacteria , also known as atypical mycobacteria or nontuberculosis mycobacteria ( ntm ) .
local water supplies are considered as the major reservoir for the m. kansasii , and evidence of person - to -... | mycobacteruim kansasii occasionally causes disseminated infection with poor outcome in immunocompromised patients .
we report the first case of disseminated m. kansasii infection associated with multiple skin lesions in a 48-yr - old male with myelodysplastic syndrome .
the patient continuously had taken glucocorti... |
production of acute inflammatory cytokines by cells of the innate immune system , including macrophages and mast cells , plays an essential role in inflammation - driven tumor development .
cytokines such as tnf , interleukin ( il)-6 , and il-1 have myriad effects in the tumor microenvironment , promoting cell growth... | mechanisms of innate and adaptive immunity play a pivotal role in the development of cancer .
chronic inflammation can drive tumor development , but antitumor immunity can also restrict or even prevent tumor growth .
new data show that feed - forward signals downstream of the receptor for advanced glycation end - p... |
population ageing is one of humanity 's greatest challenges in the 21st century , which will undoubtedly put increased health , economic and social demands on all countries . in singapore
, an integrated approach is being undertaken by the various government agencies to manage the silver tsunami. from the healthcare... | introductionpopulation ageing is one of humanity 's greatest challenges in the 21st century , which will undoubtedly put increased health , economic and social demands on all countries . in singapore
, an integrated approach is being undertaken by the various government agencies to manage the silver tsunami. from th... |
amyotrophic lateral sclerosis ( als ) is a progressive neurodegenerative disorder characterized by dysfunction and degeneration of both upper motor neurons ( umns ) in the cortex and lower motor neurons ( lmns ) in the brainstem and spinal cord that leads to muscular paralysis and ultimately death ( 1 - 3 ) .
it is t... | objective(s):amyotrophic lateral sclerosis ( als ) , a fatal progressive neurodegenerative disorder , is the most common motor neuron disease in european populations .
approximately 10% of als cases are familial ( fals ) and the other patients are considered as sporadic als ( sals ) . among many als causing genes tha... |
giant vascular eccrine spiradenoma ( gves ) is a rare highly vascular variant of eccrine spiradenoma ( es ) , as only four cases are reported in the literature ( 1 - 3 ) .
clinically , it might be mistaken for angiomatous lesions in view of its florid vascularity and hemorrhagic features .
it is well known that tum... | we report a rare case of giant vascular eccrine spiradenoma ( gves ) which developed in 56-yr - old korean woman .
it is a rare variant of eccrine spiradenoma ( es ) , which might be mistaken for angiomatous lesions in view of its florid vascularity and hemorrhagic features .
histogenesis of gves is not clearly elu... |
phosphodiesterases ( pdes ) are isoenzymes that control the level of intracellular cyclic guanosine monophosphate ( cgmp ) and cyclic adenosine monophosphate ( camp ) by hydrolyzing them .
pde isoenzyme 5 ( pde-5 ) selectively breaks down the cgmp , a critical smooth muscle tone regulator .
nitric oxide ( no ) , pr... | systemic sclerosis- ( ssc- ) related vasculopathy , as manifested by raynaud 's phenomenon ( rp ) and digital ulcers ( dus ) , is associated with significant impairment of the quality of life and morbidity . the current vasoactive approach for ssc - rp , although employing vasodilators , is entirely off - label .
pde... |
determination of mrna half - life is important to our understanding of gene expression and mechanisms involved in the regulation of the level of transcripts in response to environmental changes or developmental cues .
in addition , the stability of mrna may determine how rapidly the synthesis of the encoded protein c... | backgroundwe describe an alternative method to determine mrna half - life ( t1/2 ) based on the real - time rt - pcr procedure .
this approach was evaluated by using the -actin gene as a reference molecule for measuring of mrna stability.resultshuman leukemia nalm-6 and ccrf - cem cells were treated with various conc... |
every anesthesiologist worth their salt is guilty of administering a wrong drug at least once in their career .
most of the time the consequences have been harmless ( albeit not without feeling of guilt or remorse ) , but in some cases they have caused an undesired iatrogenic morbidity and/or mortality .
the high d... | erroneous intravenous drug administration has a high probability of causing substantial financial consequences along with patient morbidity or mortality . anesthesiologists and hospital administrators need to be cognizant of the problem .
national and international anesthesiology bodies should be involved with the me... |
gene therapy is defined as the transfer of nucleic acid molecules ( usually dna ) to a patients somatic cells in order to prevent , treat , or alleviate a specific condition .
different gene therapy strategies have been designed to suit different types of diseases , the most classical of which involves gene deliver... | artificial chromosomes and minichromosome - like episomes are large dna molecules capable of containing whole genomic loci , and be maintained as nonintegrating , replicating molecules in proliferating human somatic cells .
authentic human artificial chromosomes are very difficult to engineer because of the difficult... |
a 38-year - old man with cystic fibrosis had undergone bilateral lung transplantation in 1998 and had been well . in september 2000 , he visited a physician with a 3-day history of fever as high as 38.3c , myalgias , and headache . a resident of columbia , missouri , the patient had spent much time outdoors but did not... | we describe a case of human ehrlichiosis in a lung transplant recipient and review published reports on ehrlichiosis in immunocompromised patients . despite early therapy with doxycycline ,
our patient had unusually severe illness with features of thrombotic thrombocytopenic purpura .
of 23 reported cases of ehrlic... |
the enormous impact of cardiovascular disease on global health and economy demands that low - cost interventions , such as altered lifestyle ( e.g. diet and physical activity ) , be rigorously implemented for prevention and treatment .
dietary intake of n-3 pufas , particularly fish oil , is a propitious and therapeu... | despite their clear therapeutic effects in coronary heart disease , use of n-3 polyunsaturated fatty acids ( pufas ) to treat other types of cardiovascular disease remains controversial , and serious obstacles exist in implementing them as a reliable and consistent drug therapy .
the foremost of these is that a molec... |
spontaneous regression ( sr ) of malignant tumor was first defined by cole and everson as complete or partial clearance of malignant cells in the absence of any specific treatment , particularly antineoplastic chemotherapy or surgical resection .
it is an extremely rare phenomenon and its incidence is estimated to ... | we present an unusual case of spontaneous regression of hepatocellular carcinoma ( hcc ) . a 77-year - old man with alcoholic liver cirrhosis presented with a 50-mm tumor in the couinaud 's segment 8 ( s8 ) of the liver , a 15-mm tumor in the s8 - 7 and 10-mm tumors in the other segments ( s4 , s6 ) .
the tumors were... |
an estimated 30%70% of patients with chronic obstructive pulmonary disease ( copd ) have pulmonary hypertension ( ph).1 ph associated with copd is classified as group 3 ph by the world health organization ( who ) , which is associated with lung disease and/or hypoxemia.2 the relevance of a vascular pathology in copd is... | introductionsevere chronic obstructive pulmonary disease ( copd ) is often associated with secondary pulmonary hypertension ( ph ) , which worsens prognosis .
ph can be lowered by oxygen , but also by inhaled nitric oxide ( no ) , which has the potential to improve the health status of these patients .
no is an imp... |
riedel 's thyroiditis ( rt ) is a rare form of thyroiditis that may be related to a diverse range of clinical symptoms .
it has been reported in approximately 0.06% of patients who undergo surgery for an abnormality in the thyroid gland . although it has been assumed to be one of the clinical manifestations of multif... | riedel 's thyroiditis ( rt ) is a rare chronic inflammatory disease of the thyroid gland .
it is characterized by a fibroinflammatory process that partially destroys the gland and extends into adjacent neck structures .
its clinical manifestation can mask an accompanying thyroid neoplasm and can mimic invasive thyr... |
osteoporosis is generally considered to be a condition affecting women , but up to 30% of fragility fractures occur in men [ 13 ] .
the lifetime risk of fracture at the age of 50 years has been estimated to be 20% for men
[ 1 , 4 ] . bone mineral density ( bmd ) has long been recognised as an important skeleton det... | introduction . femoral neck shaft angle ( nsa ) has been reported to be an independent predictor of hip fracture risk in men . we aimed to assess the role of nsa in uk men .
methods .
the nsa was measured manually from the dxa scan printout in men with hip ( 62 , 31 femoral neck and 31 trochanteric ) , symptomatic ... |
in most cases , alzheimer s disease ( ad ) is preceded by a prodromal stage and amnestic mild cognitive impairment ( amci ) in which an individual s memory is impaired to a greater degree than expected given the individual s age , sex , and educational background , while the individual s ability to perform the activiti... | objectivethis study aims to apply the virtual radial arm maze ( vram ) task to find spatial working memory and reference memory impairments in patients of amnestic mild cognitive impairment ( amci ) and alzheimer s disease ( ad ) .
spatial memory functions between amci converters and nonconverters are also compared u... |
heart failure ( hf ) is a common complication of myocardial infarction ( mi ) , which may develop early or late and persist , resolve or recur . a growing proportion of patients with mi are aged > 65 years .
older patients are at greater risk of developing hf and have a poorer prognosis. surprisingly , the complex pa... | backgroundacute myocardial infarction ( ami ) is a common cause of heart failure ( hf ) , which can develop soon after ami and may persist or resolve or develop late .
hf after an mi is a major source of mortality .
the cumulative incidence , prevalence and resolution of hf after mi in different age groups are poor... |
the university of minnesota biocatalysis / biodegradation database ( um - bbd , ) contains compound , enzyme , reaction and pathway information for microbial catabolism of primarily anthropogenic materials .
it has been available on the web for over 10 years , and has grown from 4 to almost 150 pathways .
as it sta... | as the university of minnesota biocatalysis / biodegradation database ( um - bbd , ) starts its second decade , it includes information on over 900 compounds , over 600 enzymes , nearly 1000 reactions and about 350 microorganism entries .
its biochemical periodic tables have grown to include biological information fo... |
preserving the vitality of traumatically injured and mechanically exposed immature teeth is one of the major treatment aims in endodontics .
partial pulpotomy ( cvek pulpotomy ) and deep ( cervical ) pulpotomy techniques are the choices of treatment for immature permanent teeth with exposed pulps.1,2 these techniques... | this case report aimed to present the long - term clinical performance of mineral trioxide aggregate ( mta ) pulpotomies in immature permanent teeth .
four patients with complicated crown fractures of five maxillary immature central incisor teeth were treated with pulpotomy using gray mta .
an immature mandibular f... |
as
one of the most remarkable findings over the past 15 years ,
rna interference ( rnai ) is an endogenous process in which small noncoding
rnas , including small interfering rnas ( sirnas ) and micrornas ( mirnas ) ,
post - transcriptionally regulate gene expressions by binding to their
complementary mrnas .... | rna
interference ( rnai ) is an endogenous process in which small
noncoding rnas , including small interfering rnas ( sirnas ) and micrornas
( mirnas ) , post - transcriptionally regulate gene expressions . in general ,
sirna and mirna / mirna mimics are similar in nature and activity except
their origin and ... |
to become permanently immune to some illness , you must either catch it or be vaccinated against it .
vaccine is an antigenic substance prepared from the causative agent of a disease or a synthetic substitute , used to provide immunity against disease . during vaccination , a harmless version of a germ
is introduce... | a vaccine is a biological preparation that improves immunity to a specific disease .
more than two centuries have passed since the first successful vaccine for smallpox was developed .
we ve come a long way since .
today 's vaccines are among the 21st century 's most successful and cost - effective public health ... |
type 2 diabetes ( t2d ) is a multifactorial disease , caused by a complex interplay between genetic and nongenetic risk factors .
compelling evidence has identified increasing age , higher body mass index ( bmi ) , impaired fasting glucose , impaired glucose tolerance , higher glycated hemoglobin ( hba1c ) level , an... | fueled by the successes of genome - wide association studies , numerous studies have investigated the predictive ability of genetic risk models in type 2 diabetes . in this paper , we review these studies from a methodological perspective , focusing on the variables included in the risk models as well as the study desi... |
the proposed scientific , medical , and technical applications of nanomaterials have been greatly increased recently .
nanomaterials have unique physicochemical qualities compared to micromaterials in terms of size , surface structure , solubility , and aggregation .
thus , the reduction in particle size from micro... | background : the use of nanotechnology has led to rapid growth in various areas . thus , health and safety issues of nanoparticles ( nps ) should be promptly addressed .
manganese oxide ( mno2 ) nanoparticles ( nps ) are typically used for biomedical and industrial applications . however , characterizing the potentia... |
across the flowering plants ( the angiosperms ) , bilaterally symmetrical ( zygomorphic ) flowers are thought to have evolved many times independently from radially symmetrical ( actinomorphic ) ancestors .
transitions to bilateral flower symmetry have been associated with the evolution of specialized pollinators and... | cycloidea ( cyc)-like tcp genes are critical for flower developmental patterning . exciting recent breakthroughs , including a study by song et al . published in bmc evolutionary biology ,
demonstrate that cyc - like genes have also had an important role in the evolution of flower form.see research article http://www... |
among the etiologic agents of infectious disease , staphylococcus aureus , especially methicillin - resistant staphylococcus aureus ( mrsa ) strains are the main agents of human infections ( 1 ) .
this pathogen can cause nosocomial infection in such a manner that it is the most common pathogen isolated from patients ... | background : staphylococcus aureus , an important human pathogen is one of the main causative agents of nosocomial infection .
virulence genes play a major role in the pathogenicity of this agent and its infections .
methicillin - resistant staphylococcus aureus ( mrsa ) isolates are major challenge among infectiou... |
vogt koyanagi harada ( vkh ) syndrome is a rarely - seen multi - systemic , autoimmune and inflammatory disease .
it observed frequently with neurologic , auditory and skin manifestations and characterized with bilateral , chronic and diffused granulomatous panuveitis .
a 57 year - old female patient applied to a s... | backgroundvogt koyanagi harada ( vkh ) syndrome is a rarely - seen multi - systemic , autoimmune and inflammatory disease .
it observed frequently with neurologic , auditory and skin manifestations and characterized with bilateral , chronic and diffused granulomatous panuveitis .
it generally affects women in young... |
to assess the extent of promoter reuse in bacteria we looked for groups of bacterial genes per genome that share highly similar sequences upstream of their transcriptional start site , but do not have obvious flanking paralogous coding sequences . more specifically , we extracted in silico the dna region between positi... | anecdotal evidence shows promoters being reused separate from their downstream gene , thus providing a mechanism for the efficient and rapid rewiring of a gene s transcriptional regulation .
we have identified over 4000 groups of highly similar promoters using a conservative sequence similarity search in all fully se... |
obstructive sleep apnea ( osa ) is a chronic condition that affects 3 - 7% of the population . despite increasing public awareness over the last 20 years , osa is still underdiagnosed and untreated .
the negative health consequences of untreated sleep apnea continue to be elucidated , but currently include significan... | background : considering the high estimates of undiagnosed and untreated obstructive sleep apnea ( osa ) , there is a need for simple and accurate diagnostic tests .
neck circumference has long been correlated with osa , but its usefulness as a diagnostic tool has been limited.aims:we proposed to evaluate the value o... |
oral disease is considered globally one of the most common public health problems with important socioeconomic implications . among oral diseases ,
poor oral health associated with dental caries and periodontal disease may lead to loss of teeth , and can result in a number of debilitating diseases such as cardiovascu... | aims and objectives : to determine the prevalence and types of jaw pathologic findings as detected in panoramic radiographs of a sample of young women attending a teaching hospital in al madinah al munawarah , saudi arabia , and to determine the most important factors that predict the occurrence of jaw pathologic findi... |
beekeeper profit for colony i :
iv=[(1v)(hiv+riv)(ci+cv ) ] where iv is profit for colony i with varroa infestation v , hiv is honey revenue , riv is pollination rental revenues , ci is operation and maintenance costs , cv is a targeted varroa treatment cost , is the deterioration from a lack of effective varroa tre... | abstractover the past decade in north america and europe , winter losses of honey bee ( hymenoptera : apidae ) colonies have increased dramatically .
scientific consensus attributes these losses to multifactorial causes including altered parasite and pathogen profiles , lack of proper nutrition due to agricultural mo... |
astrocytes , a major glial cell type in the central nervous system , have emerged as powerful regulators of brain function where they maintain ion , metabolic , and neurochemical homeostasis .
astrocytes form organized networks that communicate through gap junctions formed by hemichannel proteins called connexins , p... | astrocytes use gliotransmitters to modulate neuronal function and plasticity . however , the role of small extracellular vesicles , called exosomes , in astrocyte - to - neuron signaling is mostly unknown .
exosomes originate in multivesicular bodies of parent cells and are secreted by fusion of the multivesicular bo... |
there is considerable evidence suggesting that cancer patients suffer from substantial and long - term psychological distress associated with different forms of cancer and its medical treatment .
cancers and any type of treatment may lead alteration in patients appearance . this issues can affect the quality of life ... | backgrounds and aim : cancer patients experience a high level of stress caused by the disease and treatment processes . dealing with cancer using more beneficial coping styles
can effectively improve the quality of life ( qol ) and reduce the side effects of cancer , and it is treatment . in this study , we aimed to ... |
to date , according to the hugo database ( www.genenames.org ) , 21 lysine demethylases have been identified in the human genome , most of which target histones in a residueselective manner.5 nineteen demethylases belong to the jumonji domaincontaining dioxygenase family , while lsd1 and lsd2 ( kdm1b ) are the only mem... | epigenetic mechanisms underlie the phenotypic plasticity of cells , while aberrant epigenetic regulation through genetic mutations and/or misregulated expression of epigenetic factors leads to aberrant cell fate determination , which provides a foundation for oncogenic transformation .
lysinespecific demethylase1 ( l... |
controlling increasing antimicrobial resistance in clinically important bacteria is a key challenge for clinicians and scientists , and there is an urgent need to prevent the emergence and subsequent spread of resistant isolates .
enterococcus faecium is a primary example of one such troublesome pathogen ; while inna... | abstractnosocomial outbreaks of vancomycin - resistant enterococcus faecium ( vrefm ) are thought to occur by transmission of vrefm between patients , predicting that infection control interventions will limit cross - transmission . despite implementation of such strategies
, the incidence of vrefm infections continu... |
genomics studies often start with the organization of a dataset retrieved from public databases , such as the ensembl.1 the ensembl database is currently in release 71 ( april 2013 ) and covers genomes from vertebrates and other eukaryotic species , and therefore holding a large amount of genomic data .
ensembl provi... | the rapid advances in genome sequencing technologies have increased the pace at which biological sequence databases are becoming available to the broad scientific community .
thus , obtaining and preparing an appropriate sequence dataset is a crucial first step for all types of genomic analyses . here
, we present ... |
mccune - albright syndrome ( mas ) is a rare disease presenting with the classical triad of
polyostotic fibrous dysplasia ( fd ) , skin hyperpigmentation ( caf - au - lait spots ) and
endocrine dysfunction , usually seen as precocious puberty in females .
the mosaicism of
mutations in the gnas1 gene results in ... | polyostotic fibrous dysplasia ( fd ) associated to mccune - albright syndrome ( mas ) often
leads to fractures , deformities , and bone pain resulting in bad quality of life .
parenteral bisphosphonates have been used in children and adolescents to improve
these symptoms with few adverse effects .
we evaluated ... |
prostate cancer ( pca ) is one of the most commonly diagnosed neoplasms in elderly men . in western europe and the usa , it is the most frequent malignant neoplasm in men and accounts for 30% of all newly diagnoses cases [ 1 , 2 ] .
the precancerous lesion of pca is considered a high grade of intraepithelial neoplas... | introductionprostate cancer ( pca ) is one of the most commonly diagnosed neoplasms in elderly men .
the precancerous lesion of pca is considered a high - grade prostate intraepithelial neoplasm ( hg - pin ) , while atypical small acinar proliferation ( asap ) is commonly considered as an under - diagnosed cancer .
... |
the etude epidemiologique de femmes de la mutuelle gnrale de l'education nationale ( e3n ) prospective cohort was initiated in france in 1990 to investigate risk factors for cancer in women ( 10 ) .
the cohort included 98,995 women living in france , aged 4065 years at baseline , who were covered by the mutuelle gnra... | objectiveobesity and increases in body weight in adults are considered to be among the most important risk factors for type 2 diabetes .
low birth weight is also associated with a higher diabetes incidence .
we aimed to examine to what extent the evolution of body shape , from childhood to adulthood , is related to... |
biological nanostructures can induce the perception of the entire range of a rainbow s color , but often only a reduced range of colors is produced in biological iridescence ; there are often sharp discontinuities between target areas that display iridescence and those that do not , and perceived colors can change dram... | summaryiridescence is a form of structural coloration , produced by a range of structures , in which hue is dependent on viewing angle [ 1 , 2 , 3 , 4 ] .
one of these structures , the diffraction grating , is found both in animals ( for example , beetles [ 2 ] ) and in plants ( on the petals of some animal pollina... |
one of the objectives of periodontal therapy is the reduction of bacterial deposits and
calculus on tooth surface .
this
objective can be achieved with hand scalers and curettes or ultrasonic scaling
instruments .
recent clinical
studies do not indicate a difference between ultrasonic / sonic and manual deb... | objectivesthe debridement of diseased root surface is usually performed by mechanical
scaling and root planing using manual and power driven instruments .
many new
designs in ultrasonic powered scaling tips have been developed .
however , their
effectiveness as compared to manual curettes has always been deba... |
these are peer - reviewed poster - platform submissions finalized by the scientific program committee . a total of 153 abstracts ( 14 platforms [ pp1 through pp14 ] & 139 posters [ 1 through 139 ] ) were selected from 161 submissions to be considered for presentation during november 4 8 , 2011 , at the hilton baltimor... | |
to address the roles of cytokines and t reg lymphocytes in immune - mediated inflammation , we have established a model in which a systemic autoimmune disease is caused by a monospecific t cell population that can be followed quantitatively in vivo . in this model , cd4 t cells from the do11.10 ( do11 ) t cell receptor... | to explore the interactions between regulatory t cells and pathogenic effector cytokines , we have developed a model of a t cell mediated systemic autoimmune disorder resembling graft - versus - host disease .
the cytokine responsible for tissue inflammation in this disorder is interleukin ( il)-17 , whereas interfe... |
in line with the global increase in prediabetes and diabetes , a significant rise in the proportion of diabetes during pregnancy has been reported .
women with diabetes are regarded as a high - risk group with respect to maternal , fetal , and neonatal outcomes . according to the medical birth registry in norway re... | aim . we regard consultations as cocreated communicatively by the parties involved . in this paper on verbal communication in midwife - led consultations , we consequently focus on the actual conversation taking place between the midwife and the pregnant woman with diabetes , especially on those sequences where the pre... |
the advent of digital fluorescence microscopy and the development of fluorescent proteins allows for unprecedented observation of molecular behavior during complex cellular processes . because visualization of fluorescent probes is possible in live cells , not only can the cellular location of proteins be studied , but... | digital fluorescence microscopy is commonly used to track individual proteins and their dynamics in living cells . however , extracting molecule - specific information from fluorescence images is often limited by the noise and blur intrinsic to the cell and the imaging system . here
we discuss a method called model ... |
alzheimer s disease ( ad ) is the most prevalent neurodegenerative condition that leads to dementia . along with memory loss and cognitive impairment
, patients with ad also suffer from dysfunctions of homeostatic and autonomic mechanisms , including mood regulation , pain perception , and sleep
wake cycles.1 such ... | objectiveamong patients with alzheimer s disease ( ad ) , sleep disturbances are common and serious noncognitive symptoms .
previous studies of ad patients have identified deformations in the brain stem , which may play an important role in the regulation of sleep .
the aim of this study was to further investigate ... |
ingestion of nitrates in drinking water has long been thought to be a primary cause of acquired infantile methemoglobinemia , often called blue baby syndrome . however ,
recent research and a review of historical cases offer a more complex picture of the causes of infantile methemoglobinemia .
gastrointestinal infe... | |
the world health organization attributes hypertension , or high blood pressure , as the leading cause of cardiovascular mortality .
an elevated arterial pressure is probably the most important public health problem in developed countries .
it is common , asymptomatic readily detectable and easily treatable , and if... | aim : the aim of this work was to determine the frequency and nature of oral manifestations in a hypertensive patient.materials and methods : the study sample consisted of 465 known hypertensive patients , between the age group of 20 - 80 years of which 250 patients were males and 215 were females .
105 were between ... |
traumatic brain injury ( tbi ) is a leading cause of morbidity and mortality in children , resulting in numerous physical , behavioral and cognitive deficits.1 ) cognitive deficits may involve problems with attention , memory and executive functions that worsen with increasing tbi severity.24 ) attention deficit hypera... | almost one - fifth of children who sustain a traumatic brain injury ( tbi ) are under the risk of attention problems after injury . the efficacy and tolerability of methylphenidate ( mph ) in children with a history of tbi
have not been completely identified . in this case report , mph - induced manic symptoms in an ... |
pantothenate - kinase - associated neurodegeneration ( pkan ) is an autosomal recessive neurodegenerative disorder that is characterized by progressive extrapyramidal signs , visual loss , and cognitive impairment .
pkan is caused by mutations in the pantothenate kinase gene ( pank2 ) , which is located on chromosome... | backgroundpantothenate - kinase - associated neurodegeneration ( pkan ) is an autosomal recessive neurodegenerative disorder that is characterized by progressive extrapyramidal signs , visual loss , and cognitive impairment .
pkan is caused by mutations in the pantothenate kinase gene ( pank2 ) , which is located on ... |
the main applications include ligand - based in silico ( virtual ) drug screening , adme - tox ( adsorption , distribution , metabolism , excretion , and toxicity ) property prediction , physical molecular property prediction ( 1-octanol - water partition coefficient , solubility ) , and measurement of the diversity of... | a molecular similarity measure has been developed using molecular topological graphs and atomic partial charges .
two kinds of topological graphs were used .
one is the ordinary adjacency matrix and the other is a matrix which represents the minimum path length between two atoms of the molecule . the ordinary adjac... |
hybrid organic inorganic
halides have been of interest since
the start of the 20th century ; however ,
the first report of a perovskite - structured hybrid halide appears
to have been by d. weber in 1978 . in the same
journal volume , he reported both ch3nh3pbx3 ( x = cl , br , i ) and the ch3nh3snbr1xix sol... | the
performance of solar cells based on hybrid halide perovskites
has seen an unparalleled rate of progress , while our understanding
of the underlying physical chemistry of these materials trails behind .
superficially , ch3nh3pbi3 is similar
to other thin - film photovoltaic materials : a semiconductor with... |
paragonimiasis is a food - borne illness of the lung caused by trematodes of the genus paragonimus .
humans can become infected with this lung fluke after consuming raw or undercooked freshwater crustaceans . before infecting mammalian hosts
, paragonimus species require a snail as the first intermediate host , and... | eggs of the lung fluke genus paragonimus were detected in red - capped mangabeys ( cercocebus torquatus ) in nigeria .
we assess the role of these primates as potential sylvatic hosts and the clinical effects of the parasite on monkeys .
dna sequenced from eggs in feces were 100% identical in the its2 region to par... |
this is a method in which one factor is varied while all other factors are fixed under certain conditions ( logothetis and wynn , 1989 ) .
however , this method does not take all factors into account at the same time .
rsm is a set of statistical techniques for designing experiments , creating models , evaluating t... | response surface methodology ( rsm ) is a useful set of statistical techniques for modeling and optimizing responses in research studies of food science . in the analysis of response surface data ,
a second - order polynomial regression model is usually used . however , sometimes we encounter situations where the fit... |
pemphigus vulgaris ( pv ) is an autoimmune disease characterized by blisters and erosion on skin and mucous membrane due to acantholysis .
it is caused by autoantibodies against desmosomal caderins desmoglein 3 ( dsg 3 ) which are cell adhesion molecules .
it affects men and woman equally and usually occurs in the ... | pemphigus vulgaris is an autoimmune disorder that involves intraepithelial blistering and sores of skin and mucous membrane .
it generally correlates with the levels of circulating autoantibodies ; their removal seems a reasonable therapeutic approach .
therapeutic plasma exchange is hypothesized to remove pathogen... |
in 2001 , an estimated 70 million americans had some form of arthritis or other rheumatic conditions , a major increase over the previous estimate of 43 million cases reported in 1997 . in 1992 ,
economy about $ 64.8 billion dollars ( about 24% was due to direct medical costs , 76% due to indirect costs from lost wag... | objectives . this study aimed to assess the health status of a nationwide sample of elderly persons having arthritis and determine the prevalence of depressive symptomatology in this population .
methods .
webtv technology was utilized to administer health status and depression surveys to a nationally representativ... |
small rna - seq raw data has been deposited in the ddbj sequence read archive ( dra ) under accession numbers dra003930 and dra004107 ( cc-124 replicate # 1 , drx040414 ; cc-124 replicate # 2 , ccdrx040415 ; gluc1( ) replicate # 1 , drx040416 ; gluc1( ) replicate # 2 , drx040417 ; ago31 replicate#1 , drr045098 ; ago31 ... | abstractwe have previously reported that the rna - binding protein dull slicer 16 ( dus16 ) plays a key role in the processing of primary mirnas ( pri - mirnas ) in the unicellular green alga chlamydomonas reinhardtii . in the present report , we elaborate on the interaction of dus16 with dicer - like 3 ( dcl3 ) during... |
laparoscopic ventral hernia repair has grown in popularity since it was first reported in the early 1990s .
lower recurrence rates , fewer complications , and shorter hospital stays have led some to believe that it sets the new standard of care for ventral hernia repair .
controversy exists regarding the optimal me... | background and objectives : mesh fixation in laparoscopic ventral hernia repair typically involves the use of tacks , transabdominal permanent sutures , or both of these . we compared postoperative pain after repair with either of these 2 methods.methods:patients undergoing laparoscopic ventral hernia repair at the mou... |
tyrosinase is a kind of oxidase enzyme that involves in reactions of melanin synthesis . in food industry ,
the inhibition of tyrosinase is very important , because this enzyme catalyzes the oxidation of phenolic compounds found in fruits and vegetables into quinones , which contribute in undesirable color and taste ... | objective(s):in food industry , the inhibition of tyrosinase is very important , because this enzyme catalyzes the oxidation of phenolic compounds found in fruits and vegetables into quinones , which contribute in undesirable color and taste of fruits and vegetables .
teucrium polium l. var .
gnaphalodes ( lamiacea... |
the story of sarcopenia has a rather recent beginning , although a search of the terms muscle wasting and sarcopenia in the online database pubmed buttresses its growing importance over the last years ( fig .
involutional changes of the musculature were described as early as 1931 by macdonald critchley , then junior ... | human muscle undergoes constant changes . after about age 50
, muscle mass decreases at an annual rate of 12 % .
muscle strength declines by 1.5 % between ages 50 and 60 and by 3 % thereafter .
the reasons for these changes include denervation of motor units and a net conversion of fast type ii muscle fibers i... |
about 80% of the rural population in sub - saharan africa depends on traditional herbal remedies for primary health care and veterinary use . in many developing countries antibiotic resistance , adverse drug reactions , and the high costs of antimicrobials
natural products of higher plants may be a source of new anti... | in kenya , leaves and roots from croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles , but reports on possible antimicrobial activity of stem bark do not exist . in this study , the antibacterial and antifungal effects of methanol , ethyl acetate and butanol extra... |
in september 1992 , 36 990 residents of takayama city , gifu , japan , aged 35 years who were not hospitalized were eligible to participate in the takayama study .
a total of 31 552 residents ( 85.3% ) participated in the baseline survey and completed a selfadministered questionnaire including an ffq .
the details ... | compared with the abundant data from western countries , evidence regarding meat consumption and colorectal cancer is limited in the japanese population .
we evaluated colorectal cancer risk in relation to meat consumption in a populationbased prospective cohort study in japan .
participants were 13 957 men and 16 ... |
a 40-year - old male patient was admitted to our hospital with amnesia , nervousness , personality changes , hostile attitudes , aggressive behaviors , hallucinations and illusions with a history of one year .
his symptoms started 3 years ago with complaints of unwillingness to move and loss of appetite .
he was co... | syphilis is a multisystem chronic infection caused by treponema pallidum .
it can cause psychiatric disorders including depression , mania , psychosis , personality changes , delirium and dementia . with the introduction of penicillin into practice ,
the number of cases with syphilis decreased and its incidence inc... |
between march 1999 and december 2002 , tae for nonvariceal upper gastrointestinal bleeding was performed in 93 patients at our institution .
the endoscopic approach had failed or was discarded because of its inability to control the bleeding in participating patients .
prospective collection of data about clinical ... | objectiveto evaluate the clinical efficacy and safety of transcatheter arterial embolization ( tae ) with n - butyl cyanoacrylate ( nbca ) for nonvariceal upper gastrointestinal bleeding.materials and methodsbetween march 1999 and december 2002 , tae for nonvariceal upper gastrointestinal bleeding was performed in 93 p... |
addressing the various needs and concerns faced by down 's syndrome ( ds ) subjects require the education of their caregivers by medical and dental professionals alike . thus providing dental health care services for individuals with special health care needs continue to be an important aspect in these patients .
oth... | objectives : to compare and quantify the presence of periodontal pathogens aggregatibacter actinomycetemcomitans ( aac ) and porphyromonas gingivalis ( pg ) in down 's syndrome ( ds ) and systemically healthy subjects with periodontitis and gingivitis.materials and methods : fifty - nine age - matched subjects were cat... |
beta - hemolytic streptococcal isolates from humans can be subdivided into large - colony and small - colony ( < 0.5 mm in diameter ) formers ( 1 ) .
the small colony - forming -hemolytic strains with lancefield group a , c , f , or g antigens belong to the anginosus or previously termed ' streptococcus milleri ' spe... | the aim of this study was to investigate antimicrobial susceptibilities and macrolide resistance mechanisms of -hemolytic viridans group streptococci ( vgs ) in a tertiary korean hospital .
minimum inhibitory concentrations ( mics ) of seven antimicrobials were determined for 103 -hemolytic vgs isolated from various ... |
a 28-year - old male visited our department with complaint of visual disturbance , hyperemia , and epiphora in his right eye , which had developed about four weeks earlier .
after symptoms developed , he visited a general ophthalmologist and was prescribed 3% acyclovir ointment ( 5 times / day ) , 1% topical predniso... | we report a case of a retained graphite anterior chamber foreign body that was masquerading as stromal keratitis .
a 28-year - old male visited with complaints of visual disturbance and hyperemia in his right eye for four weeks . on initial examination
, he presented with a stromal edema involving the inferior half... |
the effects of electromagnetic fields ( emfs ) on simple systems , such as colloids , particles in solution , and on living matter , have been investigated for many years [ 13 ] .
while high - frequency emfs produce microvibrations in the molecules that have been interpreted as resonance phenomena , elfs induce sligh... | this study investigated the effects of electromagnetic fields on enzymes involved in purine
metabolism in human peripheral blood mononuclear cells in vitro .
cells were obtained from 20
volunteers .
we tested both low - energy , extremely low frequency ( elf ; 100-hz ) electromagnetic
fields and the therapeut... |
kidney transplantation is the treatment of choice for most patients with stage five chronic kidney disease ( ckd ) .
the risk of death is less than half of that for dialysis patients regardless of the immunosuppression protocol used . furthermore , most recipients acknowledge improved quality of life .
the united n... | although current therapies for pretransplant desensitization and treatment of antibody - mediated rejection ( amr ) have had some success , they do not specifically deplete plasma cells that produce antihuman leukocyte antigen ( hla ) antibodies .
bortezomib , a proteasome inhibitor approved for the treatment of mult... |
demyelinating disorders like multiple sclerosis ( ms ) is a common cause of neurological morbidity and mortality among the general population .
rare variants of ms like balo concentric sclerosis ( bcs ) are classically considered to have a rapid progression , poor outcome , and poor response to treatment .
newer di... | the present report is a rare case of balo concentric sclerosis .
most cases have either been diagnosed post mortem or have succumbed to the disease after being diagnosed ante mortem . in our case ,
the patient showed a dramatic response to treatment , and after a one - year follow - up , he was asymptomatic , with ... |
orthodontic root resorption ( orr ) is one of the most difficult procedure - related adverse events to predict in cases of orthodontic tooth movement ( otm ) , and may cause permanent loss of the dental structure at the root apex . in an epidemiological study by kaley and phillips,1
all patients who underwent compreh... | objectiveroot mobility due to reciprocating movement of the tooth ( jiggling ) may exacerbate orthodontic root resorption ( orr ) . " jiggling " describes mesiodistal or buccolingual movement of the roots of the teeth during orthodontic treatment . in the present study ,
buccolingual movement is described as " jiggli... |
health claims are potentially powerful tools in consumer communication as they convey information on the health benefits of food or food components .
however , health claims also have the potential to misdirect consumers towards food choices that may be against their best interests .
thus , to help ensure correct h... | in this study , we investigated that consumers could differentiate between levels of claims and clarify how a visual aid influences consumer understanding of the different claim levels .
we interviewed 2,000 consumers in 13 shopping malls on their perception of and confidence in different levels of health claims usin... |
successful endodontic therapy depends on thorough chemo - mechanical preparation as well as three - dimensional obturation that provides a complete sealing of the root canal system . during cleaning and shaping procedure instrumentation with various root canal instruments leaves an amorphous , granular , and irregular ... | aim : the aim of this in vitro study is to compare the smear layer removal efficacy of different irrigating solutions at the apical third of the root canal.materials and methods : forty human single - rooted mandibular premolar teeth were taken and decoronated to standardize the canal length to 14 mm . they were prepar... |
lumbosacral nerve root anomalies are the main causes of failed lumbar surgery and intraoperative neural injury .
the most common ones are the adherent nerve root anomalies characterized by abnormal adherence of two adjacent roots . the prevalence of the disorder ranges between 1.2% and 17% , and it is as high as 6% i... | lumbosacral nerve root anomalies are the leading cause of lumbar surgery failures .
although co - occurrence of lumbar spondylolysis and disc herniation is common , it is very rare to observe that a nerve root anomaly accompanies these lesions . a 49-year - old male patient presented with sudden - onset right leg pai... |
the metabolic syndrome ( ms ) is a cluster of cardiometabolic alterations that include the presence of arterial hypertension , insulin resistance , dyslipidemia , cardiovascular disease ( cvd ) , and abdominal obesity [ 1 , 2 ] .
ms presents a prothrombotic state as a result of endothelial dysfunction , the presence ... | the metabolic syndrome is a cluster of cardiometabolic alterations that include the presence of arterial hypertension , insulin resistance , dyslipidemia , and abdominal obesity .
obesity is associated with a chronic inflammatory response , characterized by abnormal adipokine production , and the activation of proinf... |
quantitative compositional analysis of specific primary amines is applied in food science and agriculture to characterize samples for quality control .
primary amines in soil samples provide information about the available sources of organic and bioorganic n in an ecosystem , a boon for management of agriculture , an... | fluorescent probes enable detection of otherwise nonfluorescent species via highly sensitive laser - induced fluorescence .
organic amines are predominantly nonfluorescent and are of analytical interest in agricultural and food science , biomedical applications , and biowarfare detection .
alexa fluor 488 n - hydro... |
pterygium is a wing - shaped , fibrovascular growth of the bulbar conjunctiva that crosses the limbus and extends over the peripheral cornea.1 this invasion of the corneal surface can lead to significant visual morbidity caused by irritation of the ocular surface , irregular astigmatism , obstruction of the visual axis... | pterygium is a fibrovascular growth of the bulbar conjunctiva that crosses the limbus and extends over the peripheral cornea , in some cases resulting in significant visual morbidity . when treatment is indicated , surgery is necessary , and several management options exist .
these include excision , conjunctival aut... |
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