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heart failure ( hf ) has a high incidence , is one of the major causes of mortality from cardiovascular diseases in the world and is a major health problem in society . hf is divided into heart failure with reduced ejection fraction ( hfref ) and heart failure with preserved ejection fraction ( hfpef ) . in the liter...
backgroundheart failure ( hf ) is divided into heart failure with reduced ejection fraction ( hfref ) and heart failure with preserved ejection fraction ( hfpef ) . mortality from hf is inversely related to left ventricular function . additional studies are required to distinguish between these two types of hf . ...
first described by gleason in 1903 , orbital myositis ( om ) or orbital pseudotumor is a benign idiopathic inflammatory disease that may affect any structure in the orbit . ocular myositis is now seen as a subgroup within the entity of idiopathic orbital inflammatory syndrome ( iois ) and it just represent 8% of al...
we report the case of a 43 year old man who presented recurrent left abducens palsy . his medical history included arterial hypertension , ischemic cardiomiopathy , dyslipidemia , rhinitis , maxillary sinusitis . physical examination revealed a overweight patient , horizontal gaze diplopia , left nerve vi paresis , m...
the nuclear envelope ( ne ) is a biostructure , which separates the nuclear and cytoplasmic parts of eukaryotic cells . the ne is a dynamic structure composed of the outer nuclear membrane ( onm ) and the inner nuclear membrane ( inm ) . the ne is embedded with nuclear pore proteins , through which molecules select...
the nuclear lamina is the structural scaffold of the nuclear envelope that plays multiple regulatory roles in chromatin organization and gene expression as well as a structural role in nuclear stability . the lamina proteins , also referred to as lamins , determine nuclear lamina organization and define the nuclear s...
a major innovation in endodontics has been the introduction of nickel - titanium ( niti ) alloy to manufacture root canal instruments , mainly due to the superelasticity of the niti alloy , which provides increased flexibility and allows the instruments to effectively follow the original path of the root canal.1 - 5 th...
background : the multiple uses of hyflex controlled memory ( cm ) rotary instruments ( coltene - whaledent , allstetten , switzerland ) have been recommended after sterilization . the purpose of this study was to analyze the surface defects on hyflex instruments after use and to determine their ability to return to t...
central venous catheters ( cvcs ) are needed for monitoring patients in special conditions and as a route for parenteral nutrition . depending on the catheter type , cannulation is performed at different sites such as the jugular , subclavian , femoral , and brachial veins . complications associated with the cvcs a...
catheterization of central veins is a routine technique which is widely used in emergency department and medical intensive care units . seldinger 's technique is widely used to place central venous and arterial catheters and is generally considered safe . the technique does have multiple potential risks . guide w...
plants are more susceptible to the toxic effects of nitrogen dioxide when exposure takes place in the dark . beta - carotene and other common carotenoids react with nitrogen dioxide in the dark to yield intermediate nitrosating agents consistent with the formation of nitrate esters . simultaneous exposure of caroteno...
ganglioneuroma ( gn ) is a rare ( 0% to 6% of incidentalomas ) , differentiated , benign , slow - growing tumor that commonly arises from sympathetic ganglion cells and is composed of mature schwann cells , ganglion cells , and nerve fibres . the family of tumors originating from ganglion cells includes gn which is a...
we report on a 23-year - old woman with a right adrenal tumor 13 cm in diameter who was treated by laparoscopy . the patient was asymptomatic , and the tumor was incidentally diagnosed on abdominal ultrasonography . a subsequent computed tomography ( ct ) of the abdomen confirmed a 1278-cm homogenous mass of the righ...
the cyclic amp ( camp ) pathway plays fundamental roles in the nervous system , where it is prominently involved in synaptic plasticity and memory formation ( kahsai and zars , 2011 , kandel et al . , 2014 ) . previous studies in vertebrate and invertebrate models have shown that camp can propagate from dendrites to...
summarythe second messenger cyclic amp ( camp ) plays an important role in synaptic plasticity . although there is evidence for local control of synaptic transmission and plasticity , it is less clear whether a similar spatial confinement of camp signaling exists . here , we suggest a possible biophysical basis for...
it is complicated to treat patients with composite bone non - union and soft tissue defect caused by high - energy injuries , and the period of the treatment is long . due to the lack of soft tissue surrounding it , the injured bone possesses worse ability to heal and fight infection than normal bone does . in order ...
backgroundpatients with composite bone non - union and soft tissue defects are difficult to treat . vacuum - assisted closure ( vac ) combined with open bone grafting is one of the most effective treatments at present . the aim of the present study was to preliminarily investigate the effect and mechanism of vac co...
surface sampling was conducted by using swabs , wipes , and hepa vacuum socks . to compare the sampling techniques , we selected locations where the three types of samples could be collected adjacent to each other on nonporous surfaces , with an emphasis on locations believed to be still contaminated with b. anthracis ...
during an investigation conducted december 1720 , 2001 , we collected environmental samples from a u.s . postal facility in washington , d.c . , known to be extensively contaminated with bacillus anthracis spores . because methods for collecting and analyzing b. anthracis spores have not yet been validated , our obje...
in most high - income countries access to good quality , evidence - based health - care continues to improve . because of the overwhelming burden of disability caused by mental health problems throughout the world , many high - income countries have begun to address the inequity of access to mental health care with i...
inequity in health - care delivery for those with mental illness is widespread throughout low- and middle - income countries . in the pacific island countries there are many barriers to addressing the growing mental health burden . in an effort to address this problem , the who is coordinating the pacific islands m...
the human eye is prone to a number of monochromatic aberrations , including spherical , coma , astigmatism , field - curvature , and image - distortion aberrations , all of which are principally generated in the cornea and the crystalline lens.1,2 the most common aberration ( spherical aberration ) occurs when light wa...
purposeto examine the effect of misalignment ( decentration and tilt ) of intraocular lenses ( iols ) on retinal image quality using a water - immersed model eye with corneal spherical aberration adjusted to the values found in normal human eyes ( spherical aberration 0.25 m ; pupil diameter 6 mm).methodsthree types of...
q fever was first described in 1935 in queensland , australia , during an outbreak of a febrile illness of unknown origin ( query fever ) among abattoir workers . b critical biological agent by the centre for diseases control and prevention and is considered a potential weapon for bioterrorism . q fever is a publ...
q fever is an ubiquitous zoonosis caused by an resistant intracellular bacterium , coxiella burnetii . in certain areas , q fever can be a severe public health problem , and awareness of the disease must be promoted worldwide . nevertheless , knowledge of coxiella burnetii remains limited to this day . its resistan...
families are a fundamental component of the fabric of society . however , across the world , we observe important distinctions in how societies arrange familial relations . , children are brought up within varying gendered , class - based , or age - based hierarchies in the setting of their natal home . but how can w...
this article introduces a new dataset of historical family characteristics based on ethnographic literature . the novelty of the dataset lies in the fact that it is constructed at the level of the ethnic group . to test the possibilities of the dataset , we construct a measure of family constraints on women s agenc...
intramedullary spinal cord tumors ( imscts ) compromise about 2 - 4% of all central nervous system neoplasm and about 20 - 25% of all spinal tumors2,12,35 ) . surgery of imscts is very challenging to neurosurgeons , which may result of devastating neurologic deficit . recently , surgical outcomes of patients with i...
objectiverecently , surgical outcomes of patients with intramedullary spinal cord tumors ( imsct ) have been improved due to advances of medicine . the purposes of our study were to evaluate the recent neurological outcomes after surgical treatment of imscts.methodswe retrospectively reviewed 69 patients who underwen...
periprosthetic joint infection ( pji ) is one of the most serious complications that could arise after total hip arthroplasty ( tha)12 ) . although the incidence of pji ranges from 0.2% to 1%34567 ) , the pji is a significant ( or major ) cause of implant failure and requires multiple operations including revision ar...
purposeperiprosthetic joint infection ( pji ) after total hip arthroplasty ( tha ) is a grave complication . urinary tract infection ( uti ) as a source for pji is controversial . our purposes were , ( 1 ) to evaluate the incidence of pji after elective primary tha and ( 2 ) to determine whether uti was associated ...
the utah lions eye bank has harvested 159 eyes from strangulations or hangings since 2003 . of these , 18 eyes ( 11% ) were not suitable for surgery , with 13 eyes being excluded during the screening process . the reasons for exclusion included hepatitis b positivity , human t lymphotrophic virus positivity , high ...
the eyes of a 25-year - old male were collected by the utah lions eye bank after his suicide by hanging . following dissection of the corneoscleral buttons from intact globes , bilateral detached descemet s membranes with subsequent scrolling in the periphery were observed . we believe these findings were caused by...
during march and april 2011 , diagnoses of acute hev infection were made for diagnosed for 5 patients admitted to 3 hospitals in lazio : 2 in rome and 1 in latina . diagnosis was made on the basis of clinical and laboratory signs of acute hepatitis and detection of igg and igm against hev by immunoassay ( radim s.p.a...
during 2011 , 5 persons in the area of lazio , italy were infected with a monophyletic strain of hepatitis e virus that showed high sequence homology with isolates from swine in china . detection of this genotype in italy parallels findings in other countries in europe , signaling the possible spread of strains new t...
study participants were recruited from the medical retina clinic at the eye ear nose & throat hospital of fudan university , shanghai , from july 2014 to april 2016 . this study was approved by the institutional review board of eent hospital of fudan university and informed consent was obtained from all participants ...
purposewe observed and analyzed the morphologic characteristics of polypoidal lesions and abnormal branching vascular network ( bvn ) in patients with polypoidal choroidal vasculopathy ( pcv ) by optical coherence tomography angiography ( octa).methodsa retrospective observational case series was done of patients with ...
epidemiological studies have indicated that physical inactivity is associated with a variety of noncommunicable diseases ( ncds ) , and overall 1.9 million deaths are attributable to physical inactivity . hypertension is one of the most common ncds affecting a quarter to about half of the adult population in many cou...
background : to formulate all intervention strategies for hypertension in the community , it is essential to quantify the magnitude of the disease and its risk factors . the patterns of physical activity have not been studied in terms of their being a risk factor or a predictor of hypertension in saudi arabia.materials...
there is strong epidemiological evidence of excess mortality in association with the diabetic foot syndrome . there is a greater than twofold increase of mortality in diabetic foot ulcer ( dfu ) patients compared to nonulcerated diabetic patients , regardless of age , type and duration of diabetes , treatment of diab...
diabetic foot ulcer ( dfu ) patients have a greater than twofold increase in mortality compared with nonulcerated diabetic patients . we investigated ( a ) cause of death in dfu patients , ( b ) age at death , and ( c ) relationship between cause of death and ulcer type . this was an eleven - year retrospective stu...
endotoxin - induced uveitis ( eiu ) is an animal model of acute ocular inflammation . usually , this experimental pathology lasts up to 72 hours and has similarities with the human pathology . cytokines , chemokines , nitric oxide ( no ) , and impairment of stress - sensitive enzymes such as heme oxygenase-1 increa...
this study investigated whether the administration of resolvin d1 to rats with endotoxininduced uveitis ( eiu ) ameliorates the immuno - inflammatory profile of the eye . 24 h after the administration of 200 g lps into the footpad of sprague - dawley rats , severe changes of the structure of the eye occurred concom...
adrenal disorders are multifaceted involving genetics , autoimmunity , infection and environmental endocrine influences as the etiological trigger . it includes various disorders in the form of adrenal insufficiency , cushing syndrome ( cs ) , secondary hypertension ( pheochromocytoma and conn 's syndrome ) , and con...
introduction : adrenal disorders could be a life - threatening emergency , hence requires immediate therapeutic management . for this awareness regarding its diagnosis , management , and treatment is prime important.aims and objective : to study the awareness of adrenal disorders among interns and postgraduates student...
self - determination theory is a well - known psychological framework to study people 's behavior , based on the assumption that humans are innately motivated toward growth and health , a process which can be nurtured or thwarted by the social environment [ 1 , 2 ] . much research on self - determination theory , par...
this study examined the association of autonomy - related variables , including exercise motivation , with psychological well - being and quality of life , during obesity treatment . middle - aged overweight / obese women ( n = 239 ) participated in a 1-year behavioral program and completed questionnaires measuring n...
thymosin alpha 1 ( t1 ) , a 28-amino - acid peptide with molecular weight ( mw ) of 3108 da , was first isolated from calf thymus in 1977 by goldstein et al . [ 1 , 2 ] . t1 is mainly produced in vivo by thymic epithelial cells and is stable at 8090c . t1 has no aromatic amino acids ( see figure 1 ) , and n...
human thymosin alpha 1 ( t1 ) is an important peptide in the development and senescence of immunological competence in human , and many studies have reported the expression of this peptide . in this study , we designed and synthesized the t1 gene according to the e. coli codon usage preference and constructed a 6t1 con...
contact dermatitis ( cd ) in the framework of occupational diseases remains prevalent among workers worldwide , impacting their quality of life and workability . the employees most affected by cd are hairdressers , healthcare workers , and metal workers because they are continuously exposed to harmful environments ...
the leaves of artemisia argyi lev . et vant . and a. princeps pamp . are well known medicinal herbs used to treat patients in china , japan , and korea with skin problems such as eczema and itching , as well as abdominal pain and dysmenorrhoea . we investigated the anti - inflammatory effects of artemisia leaf ex...
service learning enhances student learning and engagement in undergraduate biology courses ( 1 , 2 ) , but obtaining student buy - in can be frustrating . to alleviate this issue , i had students design their own service - learning projects in my senior - level undergraduate neurobiology course . by carefully guiding s...
one of the challenges in teaching a service - learning course is obtaining student buy - in from all students in the course . to circumvent this problem , i have let students in my undergraduate neurobiology course design their own service - learning projects at the beginning of the semester . although this can be ...
recently , there has been a considerable increase in the number of hepatectomies and mortality rates reduced to less than 5% . nevertheless , surgical approach to centrally located tumours close to the confluence of the hepatic veins is still a challenging issue . trisectionectomies are considered the first option ...
surgical resection is the treatment of choice for malignant liver tumours . nevertheless , surgical approach to tumours located close to the confluence of the hepatic veins is a challenging issue . trisectionectomies are considered the first curative option for treatment of these tumours . however , those procedu...
histoid leprosy is an uncommon variant of lepromatous leprosy characterized by cutaneous / subcutaneous nodules and plaques present over apparently normal skin , with unique histopathological findings , characteristic bacterial morphology and very high bacillary load . the term histoid leprosy was coined by wade as a...
histoid leprosy is a rare form of multibacillary leprosy with distinct clinical and histopathological features . it is a variant of lepromatous leprosy with a very high bacillary load . it appears in patients as relapse after dapsone monotherapy and resistance or rarely , de novo . although leprosy is slowly de...
prostate cancer is the most frequently diagnosed solid organ cancer in men and is the second most common cause of cancer death . psa screening and testing has been shown to reduce mortality from prostate cancer and increase life expectancy . however , this has caused a tendency towards over - detection of low risk pr...
introductionwe aim to present transperineal template - guided prostate biopsy ( template biopsy ) outcomes at a tertiary referral centre . furthermore , to identify the detection rate of prostate cancer in those with a previous negative transrectal ultrasound guided prostate biopsy and the upgrade rate of those on ac...
fat at birth is unique to humans among primates , suggesting that a recently evolved genetic component accounts for this difference . body fat accumulated during intrauterine development in humans is thought to serve as an energy source to support growth of the large human newborn brain in the early neonatal period ....
increased newborn adiposity is associated with later adverse metabolic outcomes . previous genome - wide association studies ( gwas ) demonstrated strong association of a locus on chromosome 3 ( 3q25.31 ) with newborn sum of skinfolds , a measure of overall adiposity . whether this locus is associated with childhood ...
little is known about longus colli tendinitis ( lct ) , a rare inflammatory condition believed to be caused by the deposition of calcium hydroxyapatite crystals in the longus colli muscle . also known as calcific tendinitis of the longus colli muscle or retropharyngeal tendinitis , lct is characterized by the acute p...
longus colli tendinitis ( lct ) is an acute inflammatory condition with symptoms typically consisting of acute neck pain and stiffness with or without dysphagia . once more severe etiologies for these symptoms are ruled out , this self - limiting condition usually resolves spontaneously with nonsteroidal anti - infla...
the stratus td - oct had a scanning rate of 400 a - scans per second and generated a standard scanning pattern that consisted of six radial , concentric , 6-mm - long b - scans centered on the fovea and offset by 30. image quality often depended on the cooperation of the patient and the skill of the operator , since tr...
purposeto explain the pivotal role optical coherence tomography ( oct ) imaging had in the development of antiangiogenic therapies for the treatment of neovascular age - related macular degeneration ( nvamd).methodsa historical literature review was combined with personal perspectives from the introduction of oct imagi...
hyperuricemia is a condition that is significantly associated with markers of metabolic syndrome such as dyslipidemia , glucose intolerance , high blood pressure , and central obesity , which are accepted as risk factors for developing cardiovascular disease . hyperuricemia is probably associated with glucose intoler...
to determine the relationship between serum concentrations of uric acid and insulin secretion with hyperglycaemic clamp technique among adults with type 2 diabetes mellitus ( dm2 ) without hyperuricemia , we carried out a cross - sectional study on 45 patients of both gender . we observed correlation between uric aci...
the short and long - term benefits of early intervention for childhood developmental disorders have been demonstrated in numerous studies ( 16 ) and an increasing urge has been developed for their early identification ( 6 ) . however , it is now well - known that relying on a clinician s clinical instincts and experi...
backgroundto provide the validated and standardized form of the persian version of the ages and stages questionnaires as an appropriate developmental screening tool for evaluation of iranian children s development.methods:this was a cross - sectional study . translation and back - translation , content validity deter...
ethiopia is one of the few countries with the highest number of people living with hiv / aids globally . according to ethiopian demographic and health survey ( edhs ) 2011 , federal ministry of health ( fmoh ) and hiv / aids prevention and control office ( hapco ) estimated that adult hiv prevalence was 1.5% a fee - ...
background . there has been a rapid scale up of antiretroviral therapy ( art ) in ethiopia since 2005 . we aimed to evaluate mortality , loss to followup , and retention in care at hiv clinic , university of gondar hospital , north - west ethiopia . method . a retrospective patient chart record analysis was perform...
conventional open surgery is the preferred treatment for tumor resection , as is for intrahepatic bile duct stones , especially in patients who have undergone previous upper abdominal surgery . in recent decades , continuous innovation and improvement of laparoscopic equipment and technology have led to the evolution...
background : laparoscopic liver resection has become an accepted treatment for liver tumors or intrahepatic bile duct stones , but its application in patients with previous upper abdominal surgery is controversial . the aim of this study was to evaluate the feasibility and safety of laparoscopic hepatectomy in these ...
recently , a possible disparity in the degree to which the right and left hand are susceptible to optical illusions when grasping or pointing at objects has received considerable attention ( de grave et al . 2009 ; gonzalez et al . the interest is motivated by the two - visual systems model for action and perception ...
we investigated whether the control of movement of the left hand is more likely to involve the use of allocentric information than movements performed with the right hand . previous studies ( gonzalez et al . in j neurophys 95:34963501 , 2006 ; de grave et al . in exp br res 193:421427 , 2009 ) have reported cont...
scientific workflows attempt to automate repetitive computation and analysis by chaining together related processes . automating repetitive time - consuming tasks allows scientists to keep pace with ever - growing volumes of data ( 1 ) . furthermore , workflows can aid in the reproducibility of scientific computation...
the bioextract server ( bioextract.org ) is an open , web - based system designed to aid researchers in the analysis of genomic data by providing a platform for the creation of bioinformatic workflows . scientific workflows are created within the system by recording tasks performed by the user . these tasks may inc...
lung cancer is the leading cause of cancer among men in india . according to international agency for research on cancer , 43,500 indian patients are diagnosed with lung cancer every year and 37,500 die of the disease . adjuvant chemotherapy is generally indicated for patients with resected stages ib through iiia n...
background : gefitinib , an epidermal growth factor receptor - tyrosine kinase inhibitor , represents a new treatment option for patients with advanced non - small - cell lung cancer ( nsclc ) . we analyzed the data of patients who received gefitinib for nsclc in a tertiary care center in south india.materials and me...
the widespread use of pesticides contributes to population declines and mortality of birds in agroecosystems . among the various categories of pesticides , insecticides typically present a higher risk of acute effects [ 2 , 3 ] because of their elevated inherent toxicities and high potential for exposure . document...
it is generally assumed that the toxicity of pyrethroid insecticides to birds is negligible , though few species have been tested . the oral acute toxicity of formulated beta - cyfluthrin was determined for canaries ( serinus sp . ) , shiny cowbirds ( molothrus bonariensis ) , and eared doves ( zenaida auriculata ) ....
factors contributing to the steady rise in prevalence of periodontal disease include poor oral health awareness . annual health budget is 2% of gross national product but no specific budget is earmarked for oral health . oral health knowledge is considered to be an essential prerequisite for health - related behavi...
background : according to world oral health report 2003 , the prevalence of periodontitis is 86% in india . dental care can sometimes be a forgotten part of a healthy life style . while its importance is often underestimated , the need for regular dental care can not be overstated . oral health has been neglected...
breast cancer ( bc ) is the most common cancer among american women , with more than 200,000 new cases diagnosed each year . the lifetime risk for developing breast cancer has been reported to be as high as 12% , whereas the risk of death has been reported to be as high as 5% . in mexico in 2007 , there were 16,340 r...
the purpose of this study was to analyze the prognostic and predictive factors that relate to locoregional or distant recurrences in breast cancer patients who have been treated at the national cancer institute of mexico . multivariate , time - dependent cox regression analyses indicate that the pn status ( positive ...
the temporal and spatial coupling between increased neuronal activity and cerebral blood flow ( cbf ) , known as functional hyperemia or neurovascular coupling , is a highly regulated phenomenon that ensures adequate supply of oxygen and glucose to the neurons at work during a given task . although intuitively appealin...
in this article , we will review molecular , anatomical , physiological and pharmacological data in an attempt to better understand how excitatory and inhibitory neurons recruited by distinct afferent inputs to the cerebral cortex contribute to the coupled hemodynamic response , and how astrocytes can act as intermedia...
coronary artery spontaneous dissection is a rare and uncommon cause of sudden cardiac death and acute coronary syndrome . we report a case of a 31-year - old male admitted to our hospital with an acute coronary syndrome . a dissection of the left main coronary artery was diagnosed with a multidetector computed tomo...
spontaneous dissection of the coronary arteries is a rare disease with a wide range of clinical presentations ranging from angina to myocardial infarction ( mi ) ; its pathophysiology has not yet been fully established . in this paper , we present the case of a 31-year - old male with an acute coronary syndrome . the...
reducing under - five mortality is now a global concern . in 2001 as part of the millennium development goals ( mdg ) for health , nations pledged to ensure a two - thirds reduction in under - five mortality between 1990 and 2015 and at once a series of articles in lancet by the bellagio study group described various a...
objectivesin india there has been a decline in overall under - five mortality , with some states still showing very high mortality rates . it is argued that there is family clustering in mortality among children aged < 5 years . we explored the effects of programmable ( proximate ) determinants on under - five mort...
thirty two consecutive patients with jme admitted at the epilepsy clinic of sina hospital , and 32 healthy controls in tehran , iran were enrolled in the study . jme was diagnosed using international league against epilepsy ( ilae ) classification ( 6 ) . entry criteria for patients included normal brain mri , age ...
objectivethe aim of present study was to verify possible cognitive dysfunction in the patients with juvenile myoclonic epilepsy ( jme ) and its correlation to factors related to epilepsy and patients demographic variables.material and methodsthirty two consecutive patients with jme and 32 healthy controls were evaluate...
type 2 diabetes is characterized by chronic hyperglycemia resulting in microvascular and macrovascular complications which may contribute to an increased risk of early cardiovascular morbidity and early mortality . now - a - days , the primary approach for type 2 diabetes management is steadily and continuously blood...
background : at present , china has listed the compound tablet containing a fixed dose of rosiglitazone and metformin , avandamet , which may improve patient compliance . the aim of this study was to evaluate the efficacy and safety of avandamet or uptitrated metformin treatment in patients with type 2 diabetes inade...
family planning is done for future pregnancies with the goal of prevention from unplanned pregnancies , which plays a major role in the improvement of maternal health , especially in developing countries . the negative outcome of not using a reliable contraceptive method is an unexpected pregnancy , which has physica...
background : quality of services , making communications with target groups , and educating them are among the most important success factors in implementation of family planning programs . provision of public access to contraception and related methods , counseling services , and paying attention to social specifica...
epidemiology of malocclusion and assessment of orthodontic treatment needs are of national importance in many countries and were thus included in numerous national level surveys [ 116 ] . malocclusion features the third highest prevalence among oral pathologies , secondarily to dental caries and periodontal disease a...
objective . to evaluate the prevalence of malocclusion and orthodontic treatment needs among 12- to 15-year - old schoolchildren in eastern nepal and compare the findings with those of other populations . methods . two thousand seventy - four children ( 1149 males and 925 females ) aged between 12 and 15 years were e...
we analyzed the sample of older adults ( 65 years of age or older , n = 3,810 ) participating in nhanes 19992004 , a continuing statistical survey of the noninstitutionalized civilian u.s . all study participants have blood pressure measurements taken , whereas those in the nhanes morning subset ( n = 1,556 ) also ha...
backgroundadults aged 65 and older are disproportionately affected by hypertension , dyslipidemia , and diabetes , which are established risk factors for cardiovascular disease ( cvd ) . although risk reduction strategies among older adults , including control of cvd risk factors , can lead to a decline in premature ...
acinetobacter baumannii was recently recognized as a successful nosocomial pathogen , with an increasing morbidity and mortality due the rise in multi- and pan - drug - resistant strains ( perez et al . its clinical importance led to extensive studies on different aspects of the biology and pathogenesis ( mcconnell e...
recent studies have demonstrated a high genomic plasticity in acinetobacter baumannii , which may explain its high capacity to acquire multiple antibiotic resistance determinants and to survive in the hospital environment . acinetobacter baumannii strain a118 ( ab a118 ) was isolated in the year 1995 from a blood cul...
among smokers who are aware of the ill effects of smoking , 3 out of 4 individuals are interested in quitting . one of the most important responsibilities of a countries health care system is to treat nicotine dependence . this effort consists of different methods such as simple clinical counseling , medications an...
background : during recent years , there have been many advances in different types of pharmacological and non - pharmacological tobacco control treatments . in this study , we aimed to identify the most effective smoking cessation methods used in quit based upon a review of the literature.methods:we did a search of pu...
the overall incidence of ovarian tumors in pregnancy is 2.4 - 5.7% ( 1 ) . of these tumors , currently , an ultrasound is routinely used early in pregnancy , and this has led to an early diagnosis and management of asymptomatic ovarian tumors . in contrast to previous guidelines for managing gynecological malignanc...
the aim of this study is to evaluate the clinical feature and pregnancy outcome in patients with ovarian cancer diagnosed during pregnancy . we retrospectively analyzed the medical records of 27 patients diagnosed with ovarian cancer during pregnancy at cheil general hospital & women 's healthcare center from january...
sincipital encephaloceles , also called frontal or anterior encephaloceles , are rare neural tube defects and are more common in south and southeast asian populations . in children with sincipital encephaloceles there are often significant associated intracranial anomalies , including intracranial cysts , complete / ...
objective : the aim of this study was to evaluate the associated intracranial malformations in patients with sincipital encephaloceles.materials and methods : a hospital - based cross - sectional study was conducted over 8 years from june 2007 to may 2015 on 28 patients . the patients were evaluated by either compute...
today , most newborns in the united states are vaccinated against the hepatitis b virus , usually in the first few days of life.1 the practice of vaccinating infants against hepatitis b , a blood - borne virus that attacks the liver , is a popular target for contemporary vaccine critics , who for the last decade have a...
in the decade following hepatitis b vaccine s 1981 approval , u.s . health officials issued evolving guidelines on who should receive the vaccine : first , gay men , injection drug users , and healthcare workers ; later , hepatitis b - positive women s children ; and later still , all newborns . states laws that ma...
endoscopic submucosal dissection ( esd ) has been performed widely and safely as an established treatment for superficial esophageal neoplasms.1 to date , the indication for esd has been gradually extended to larger lesions . however , as large superficial esophageal neoplasms became candidates for esd , a substantial ...
stricture frequently occurs after endoscopic submucosal dissection ( esd ) for superficial esophageal carcinoma with near- or whole - circumferential mucosal defects , and post - esd stricture is difficult to treat and usually requires multiple sessions of endoscopic balloon dilatation . intralesional steroid injecti...
the abuse of illicit drugs such as opiates is a worldwide problem for both the users and society . drug abuse is linked with a number of diseases , including hiv and hbv infections and other communicable diseases , and many drug addicts die of either the drug itself or complications from use everyday . in china , t...
summarybackgroundthere have been few studies conducted on the oral health status of illegal drug users in china , affecting the development of preventive and therapeutic approaches . the aim of the present study was to investigate and analyze the oral health status of former heroin users treated with methadone in che...
muscle specimens were also examined by electron microscopy , which was performed as described previously . b - cell clonality was assessed in both patients ' specimens by pcr amplification using a set of biomed-2 assays ( invivoscribe technologies , san diego , ca ) . loci for igh [ igha : fr1 ( variable region fra...
objective : to investigate the clinical and morphologic spectrum of early adult onset dermatomyositis ( dm ) , an inflammatory disease that affects small vessels of the muscle and the skin.methods:histologic evaluation of frozen muscle samples was employed to visualize the cellular organization of ectopic lymphoid str...
subclavian artery stenosis or occlusion has a low prevalence ( 1.9% ) and is asymptomatic in most cases . not all symptomatic patients require treatment . similar to the treatment of peripheral arterial disease in the lower limb ( tasc ii ) , we would expect endovascular revascularisation to be the preferable treat...
introductionstenosis of the subclavian artery is uncommon and it rarely causes symptoms . only symptomatic patients should be treated.presentation of casewe report a case of chronic left upper limb ischemia caused by subclavian artery stenosis after repetitive clavicular fixation . the stenosis was first treated with...
immunotherapies have shown promising results in cancer types previously hard to cure , such as melanoma,1 , 2 , 3 non - small cell lung cancer , and renal cell carcinoma . in addition to checkpoint - inhibiting antibodies , patient - derived t cells are a potent approach because they can be re - targeted against tum...
adoptive cell therapy holds much promise in the treatment of cancer but results in solid tumors have been modest . the notable exception is tumor - infiltrating lymphocyte ( til ) therapy of melanoma , but this approach only works with high - dose preconditioning chemotherapy and systemic interleukin ( il)-2 postcond...
the purpose of experiment 1 was to clarify whether a smaller balloon catheter can reduce bladder damage . the purpose of experiments 2 and 3 was to determine , if the catheter based on the results of experiment 1 can be used in a nutritional trial requiring daily urine collection . for this purpose , we investi...
abstractthis study proposed a modified procedure , using a small balloon catheter ( sb catheter , 45 ml ) , for reducing bladder damage in cows . holstein cows and the following catheters were prepared : smaller balloon catheter ( xsb catheter ; 30 ml ) , sb catheter and standard balloon catheter ( nb cathete...
diabetes mellitus is a heterogeneous group of metabolic diseases that is characterised by hyperglycaemia . it can result in blindness , kidney and heart disease , stroke , loss of limbs , and reduced life expectancy if left untreated and is recognized as a primary threat to human health in the 21st century . type 2...
animal models have provided important information for the genetics and pathophysiology of diabetes . here we have established a novel , nonobese rat strain with spontaneous diabetes , long - evans agouti ( lea ) rat derived from long - evans ( le ) strain . the incidence of diabetes in the males was 10% at 6 month...
carcinoid tumors represent a group of well - differentiated tumors originating from the diffuse endocrine system outside the pancreas and thyroid . the overall prevalence of carcinoid tumors in the united states is estimated to be one to two cases per 100,000 persons . various sites of origin of this neoplasm are a...
context : carcinoid tumors represent a group of well - differentiated tumors originating from the diffuse endocrine system outside the pancreas and thyroid . the overall prevalence of carcinoid tumors in the united states is estimated to be one to two cases per 100,000 persons . various sites of origin of this neop...
subtilisin solutions were prepared by mixing and vortexing of 1.25 , 5 , 8 , 12.5 , 15 , 17.5 , 20 , and 25 l of subtilisin stock solution ( sigma aldrich , catalogue number p4860 ; lot 056k1213 ) per ml of 100 mm phosphate buffer ( ph = 8 , filtered with a 0.25 m anotop filter ) , which yielded enzyme solutions at con...
the structural characterization of subtilisin mesoscale clusters , which were previously shown to induce supramolecular order in biocatalytic self - assembly of fmoc dipeptides , was carried out by synchrotron small - angle x - ray , dynamic , and static light scattering measurements . subtilisin molecules self - as...
porous ni materials , such as plaques and foams , are widely used in industry for the fabrication of electrodes for rechargeable batteries . nanostructured active materials are impregnated chemically or electrochemically into the porous ni structures , which are used as current collectors . ni plaques are current c...
manganese dioxide nanofibers with length ranged from 0.1 to 1 m and a diameter of about 46 nm were prepared by a chemical precipitation method . composite electrodes for electrochemical supercapacitors were fabricated by impregnation of the manganese dioxide nanofibers and multiwalled carbon nanotubes ( mwcnt ) into ...
gmc , also named injection contracture , is a clinical syndrome characterized by gait abnormality and limb dysfunction including restriction of adduction and internal rotation of the hip joint . it was first found by valderrama at a scientific meeting of the british orthopedic association in london in 1969 . its ...
abstractgluteal muscle contracture ( gmc ) , presented with hip abduction and external rotation when crouching , is common in several ethnicities , particularly in chinese . it remains unclear that the reasons why these children are weak and have no choice to accept repeated intramuscular injection . here , we foun...
non - traumatic convexal subarachnoid hemorrhage ( csah ) observed at the convexity of the brain is a relatively uncommon entity with various vascular and nonvascular causes . : cerebral venous thrombosis ( cvt),1 ) reversible cerebral vasoconstriction syndrome ( rcvs),4 ) vascular malformations , vasculitides,12 ) i...
non - traumatic convexal subarachnoid hemorrhage ( csah ) is a comparatively infrequent with various vascular and nonvascular causes , it rarely occurs concomitant to acute ischemic stroke . we report a case of a 59-year - old woman , visited emergency room with right side subjective weakness spontaneously . magnet...
adult obesity has become a disease of epidemic proportions , and it is well known as a root cause of multiple medical comorbidities . conservative treatment options for the obese , such as low - calorie diets , behavior modifications , and exercise , are still the mainstay of therapy . unfortunately , the results o...
background : gastrogastric fistula is a communication between the proximal gastric pouch and the distal gastric remnant , rarely described in the realm of bariatric procedures . the aim of this study was to review the existing literature about this topic and to demonstrate its laparoscopic treatment.methods:an extensiv...
hepatitis g virus ( hgv ) belongs to the flaviviridae , which includes three genus and more than 70 members . hepatitis g virus members are widely variable and biologically different ( 1 , 2 ) . despite the gene structure and duplication similarities , there is no antibody cross - reactivity among hgv members prote...
background : hepatitis g virus ( hgv ) is a member of flaviviridae . prevalence of hgv in healthy people is very low , but this virus is more prevalent in patients with hepatitis . besides , relative frequency of hgv in patients undergoing hemodialysis , and kidney recipients is very high . the role of hgv in patho...
while stoke incidence has declined in developed countries over the last decade , its incidence rose during the same period in low- and middle- income countries . although stroke is an ever - increasing problem in developing countries , little is known about its incidence and outcomes in sub - saharan africa ( ssa ) ....
the aim of the present study was to investigate the association of apoe , mthfr and ace polymorphisms with stroke in the zambian population . we analyzed 41 stroke patients and 116 control subjects all of zambian origin for associations between the genotype of the apoe , mthfr and ace polymorphisms and stroke . the...
chronic venous insufficiency ( cvi ) is characterised by the retrograde flow of blood in the lower extremity . cvi and its sequel of varicose veins and venous hypertension are among the most common disorders that affect daily life1 . the annual incidence of cvi is 26% and 1.9% in women and men , respectively2 ....
[ purpose ] this study was aimed to analyse the effects of short - term use of compression stockings ( cs ) on symptoms and qol in patients with chronic venous insufficiency ( cvi ) . [ subjects and methods ] based on the ceap classification c2 and c3 , 117 patients with cvi were enrolled in this study . the pa...
a 30-year - old caucasian woman presented to the emergency department with self - limited severe chest heaviness , which started at rest and lasted for three hours . medication usage included an oral contraceptive ( ocp ) , alprazolam , citalopram , and lansoprazole . laboratory data were significant for a white bl...
spontaneous coronary artery dissection ( scad ) is a rare and often lethal cause of acute coronary syndrome , which typically affects young women and otherwise healthy individuals . scad can be diagnosed in patients undergoing coronary angiography and can be underestimated . special techniques such as optical coher...
multiple myeloma ( mm ) is a malignant disorder characterized by multifocal proliferation of clonal , long - lived plasma cells within the bone marrow ( bm ) . mm presents clinically with a broad range of manifestations , including skeletal destruction , immune suppression , and end - organ sequelae . it is estimat...
backgroundsymptomatic multiple myeloma ( mm ) evolves from an asymptomatic precursor state termed monoclonal gammopathy of undetermined significance ( mgus ) and smoldering myeloma ( smm ) . angiogenesis plays a key role in the pathogenesis of mm but there are very limited data for angiogenesis in smm.material/method...
the pneumococcal polysaccharide conjugated vaccine ( 13-valent , adsorbed ; pcv13 , prevnar 13 ) is approved in adults 50 years for the prevention of pneumonia in the usa [ 13 ] . lichenoid dermatitis describes a skin condition that is microscopically characterized by band - like lymphocytic inflammation with altera...
backgroundcutaneous dermatoses and malignancies have occurred at the sites of vaccines.purposeto describe a man who developed a lichenoid dermatitis at the pneumococcal vaccine injection site and to review cutaneous dermatoses and malignancies occurring at vaccination sites.methodspubmed was used to search the followin...
substance use on american college campuses is a significant public health problem with adverse effects including but not limited to impaired academic performance , interpersonal violence , acute injuries , and increased risk of mortality . cigarette smoking is an established risk factor for coronary heart disease , a...
a randomized wait - list controlled trial ( n = 295 university students ) of the effects of the transcendental meditation program was conducted in an urban setting . substance use was assessed by self - report at baseline and 3 months later . for smoking and illicit drug use , there were no significant differences be...
rheumatic heart disease ( rhd ) , the primarily autoimmune sequelae of acute rheumatic fever ( arf ) , is an autoimmune disease that arises following infection by s. pyogenes in people ages 319 years . the disease remains a major cause of cardiovascular disability in the young , and imposes a heavy burden on public h...
backgroundrhd is an autoimmune disease that arises following infection by s. pyogenes and imposes a heavy burden on public health.material/methodswe detected 11 selected mirnas expressed in the cardiac tissues of 11 rhd patients and 11 controls . by employing dual - luciferase assay and western blot , we identified t...
a 72-year - old male patient visited smg - snu boramae medical center with exertional chest pain , which had been aggravated during the most recent 3 months . the initial electrocardiogram revealed sinus bradycardia with a heart rate of 50 beat per minute , and there was no st segment elevation . the serum cardiac ...
recurrent ventricular arrhythmia can be fatal and cause serious complications , particularly when it is caused immediately after an operation . incorrect placement of a swan - ganz catheter can trigger life - threatening ventricular arrhythmia , but even intensive care specialists tend to miss this fact . here , we r...
we report a novel method for the measurement of lipid nanotube radii . membrane translocation is monitored between two nanotube - connected vesicles , during the expansion of a receiving vesicle , by observing a photobleached region of the nanotube . we elucidate nanotube radii , extracted from spe vesicl...
since the first report on the use of the combination of gonadotropin - releasing hormone agonists ( gnrha ) and gonadotropins for in vitro fertilization ( ivf ) in 1984 ( 1 ) , gnrha has widely been used in controlled ovarian stimulation cycles for assisted reproduction . one known complication of pituitary down - re...
several case reports have indicated that a small subgroup of patients may develop ovarian hyperstimulation following the administration of gonadotropin - releasing hormone agonists ( gnrha ) without gonadotropins . however , since only few such cases have been published , it is unclear what course to follow in subseque...
asthma is a chronic inflammatory disease of the airways characterized by bronchial hyperresponsiveness , variable airflow limitation , and symptoms such as dyspnea , wheezing , and cough , which improve spontaneously or with treatment . the primary goals of asthma treatment include complete symptom control , optimal ...
objective : to evaluate respiratory muscle strength and six - minute walk test ( 6mwt ) variables in patients with uncontrolled severe asthma ( ucsa ) . methods : this was a cross - sectional study involving ucsa patients followed at a university hospital . the patients underwent 6mwt , spirometry , and measurements ...
mucus extravasation cysts or mucoceles are an extremely common lesion of the minor salivary glands . we report upon an unusual case of a submandibular gland mucocele presenting as a lateral neck swelling . the term plunging or cervical ranula refers to mucoceles that extend below the mylohyoid muscle , beyond the s...
mucus extravasation cysts or mucoceles are an extremely rare occurrence in the major salivary glands . we report upon an unusual case of a submandibular gland mucocele presenting as a neck lump . it should therefore be considered in the differential diagnosis of swellings in the lateral neck . diagnosis and manag...
increasing evidence from animal and human studies points to a nonnegligible role for the innate and adaptive immune system in the development of atherosclerosis , still the leading cause of cardiovascular morbidity and mortality in our western society [ 14 ] . in fact , it is estimated that approximately 30% of all d...
atherosclerosis remains the leading cause of death and disability in our western society . to investigate whether the dynamics of leukocyte ( sub)populations could be predictive for plaque inflammation during atherosclerosis , we analyzed innate and adaptive immune cell distributions in blood , plaques , and lymphoid...
' mesotherapy ' is a non - surgical , minimally invasive method of drug delivery that consists of multiple intradermal or subcutaneous injections of a mixture of compounds ' melange ' in minute doses . it has gained disrepute because of inadequate scientific evidence to prove its efficacy . in spite of this , many ...
mesotherapy refers to multiple injections of small quantity of the drug over a large area . the mesoguns available are expensive and the motor - driven models tends to waste the expensive material to be injected since the plunger stops after injecting without recoil . we searched for a less expensive device which w...
as antiretroviral therapy ( art ) coverage in sub - saharan african ( ssa ) populations continue to increase , deaths from hiv / aids has dramatically declined in the past decade . in ssa and other resource limited settings ( rls ) , where stavudine - containing art regimens have been extensively used , a wide range ...
introduction . while the introduction of highly active antiretroviral therapy decreased hiv - related morbidity and mortality rates in the sub - saharan africa , a subsequent increase in metabolic abnormalities has been observed . we sought to determine the prevalence of hiv - associated metabolic abnormalities among...
for decades , critical care medicine and nephrology have been fighting but finally emerged altogether with the concept of critical care nephrology almost 20 years ago.1 emergency and critical care medicine have grown into robust self - supporting disciplines with an increasing demand for dedicated highly - skilled phys...
emergency and critical care medicine have grown into robust self - supporting disciplines with an increasing demand for dedicated highly - skilled physicians . in the past , core specialists were asked to offer bedside advice in acute care wards . in the same regard , critical care medicine and nephrology have bee...
many exanthemata initially present very similarly , even though caused by different organisms ranging from virus to bacteria as well as having different rates of morbidity and mortality . in the majority of cases however , in some cases accurate and prompt diagnosis is paramount , since therapy and appropriate hygi...
childhood exanthemata are caused by a broad spectrum of common pathogens . many exanthemata initially present very similarly , even though caused by different organisms , ranging from virus to bacteria and their respective toxins . in the majority of cases the diagnosis is only of academic value , since therapy doe...
the two most common forms of senile dementia , alzheimer s disease ( ad ) and vascular dementia ( vad ) , share many of the same clinical signs and symptoms . both diseases are characterized by cognitive decline , functional deterioration and neuropsychiatric symptoms that may present as behavioral alterations.1 vasc...
although ideomotor limb apraxia is considered to be a typical sign of cortical pathologies such as alzheimer s disease ( ad ) , it has been also reported in subcortical neurodegenerative diseases and vascular lesions . we aimed to investigate the difference between ad , subcortical vascular dementia ( svad ) and mild...
heidelberger and his postdoctoral fellow forrest kendall who had been rendered one handed ( but , by all accounts , no less dextrous ) by a farm threshing machine took advantage of purified bacterial polysaccharides ( isolated during their earlier studies ) for their quantitative experiments . they incubated varyin...
having defined the protein nature of antibodies under the tutelage of oswald avery , michael heidelberger was the first to apply mathematics to the reaction of antibodies and their antigens ( the precipitin reaction ) . heidelberger 's calculations launched decades of research that helped reveal the specificity , f...
peripheral giant cell granuloma ( pgcg ) is the most common oral giant cell lesion appearing as a soft tissue extra - osseous purplish - red nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells . this lesion is probably not present as a true neo...
peripheral giant cell granuloma or the so - called giant cell epulis is the most common oral giant cell lesion . it normally presents as a soft tissue purplish - red nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells . this lesion probably...
prepare the following solutions ( see table 1 for compositions ) : ( a ) 1 liter nfr ( normal frog ringer ) , ( b ) 100 ml 10% saline , ( c ) 100 ml cmf ( ca /mg - free solution ) , ( d ) 1 ml its ( insulin - transferrin - selenium , sigma i1884 ) , ( e ) 100 ml l-15 culture medium , ( f ) 10 ml hcg ( human chorionic g...
much information about the coupling of presynaptic ionic currents with the release of neurotransmitter has been obtained from invertebrate preparations , most notably the squid giant synapse1 . however , except for the preparation described here , few vertebrate preparations exist in which it is possible to make simult...
central serous chorioretinopathy ( cscr ) is a condition characterized by the accumulation of subretinal fluid at the posterior pole of the fundus , causing single or multiple areas of serous retinal detachment . the pathophysiology of the disease is thought to involve retinal pigment epithelial ( rpe ) dysfunction ,...
we present a case of bilateral multifocal central serous chorioretinopathy in a 40-year - old male who suffered from myasthenia gravis and was receiving oral prednisolone . due to the severity of the underlying disease , it was not possible to reduce the corticosteroid dose . after initial unsuccessful treatment with...
talipes equinovarus is the most common congenital foot deformity diagnosed in newborns . serial manipulative casting by the use of plaster of paris ( pop ) has been accepted as the primary treatment modality to correct this multiplanar deformity . application of serial manipulative pop casts was first introduced and ...
abstractrandomized controlled clinical trial.the main purpose of the present study was to comparatively analyze the effectiveness , advantages , and the complications of using semirigid synthetic softcast with respect to plaster of paris ( pop ) during the treatment of clubfoot deformity.the study group consisted of 19...
diabetic nephropathy ( dn ) is one of the most common microvascular complications of diabetes mellitus ( dm ) and a leading cause of end - stage renal disease ( esrd ) . china currently has approximately 100 million adults with type-2 diabetes and 150 million people with prediabetes [ 2 , 3 ] . alarmingly , 120 mil...
purpose . the objective of this study is to investigate the effect of dual blockage of renin - angiotensin system ( ras ) on renal kallikrein expression and inflammatory response in diabetic nephropathy ( dn ) . methods . rats were randomly divided into 5 groups with 10 rats in each group : normal control ; dn mo...
a multiplex pcr solution specifies a forward and reverse primer for each single nucleotide polymorphism ( snp ) and assigns each primer pair to one of a finite set of tubes . in partitioning snp primers into individual tubes , care must be taken to ensure that all primers within a tube are mutually compatible , i.e. ...
we have developed a web - enabled system called muplex that aids researchers in the design of multiplex pcr assays . multiplex pcr is a key technology for an endless list of applications , including detecting infectious microorganisms , whole - genome sequencing and closure , forensic analysis and for enabling flexib...
a two - way process of exchanging or shaping ideas , feelings , and information between dentist and patient has created keen interest in dental society . the best way to achieve effectively exchanging and shaping ideas depend on the credibility of the dentist that is how he defines empathy practically . empathy is to...
background : empathy plays an important role in healthy dentist and patient relationship . hence , the aim of the study is to ( a ) to measure the self - reported empathy levels among dental undergraduate and postgraduate students . ( b ) to review the trend of changes in empathy level with experience , age , and g...
one of the most important objectives of endodontic therapy is to completely eliminate intracanal microorganisms from the root canal system to create favorable environment for healing and to prevent reinfection in order to achieve long - term success . are polymicrobial in nature with predominant anaerobic microorgani...
aim / objective : the aim of this study is to compare the antimicrobial efficacy of qmix 2 in 1 , sodium hypochlorite ( naocl ) , and chlorhexidine ( chx ) against enterococcus faecalis and candida albicans.materials and methods : eighty freshly extracted , single - rooted human mandibular premolar teeth were instrumen...
the incidence of laryngeal cancer has decreased in the usa in recent years as rates of smoking have declined . however , larynx cancer continues to be a serious problem for individuals suffering from this disease , with treatment frequently affecting the patient 's ability to phonate and swallow . this year , 12630 p...
background . salivary fistula is a common complication after salvage total laryngectomy . previous studies have not considered the number of layers of pharyngeal closure and have not classified fistulas according to severity . our objective was to analyze our institutional experience with salvage total laryngecto...
resistance training is a commonly prescribed and broadly researched rehabilitative strategy for older adults to maintain or improve muscle strength and function . resistance training interventions typically emphasize high - load , strengthening exercise ; however , muscle power ( force velocity ) has emerged as an i...
we examined whether high - speed power training ( hspt ) improved muscle performance and braking speed using a driving simulator . 72 older adults ( 22 m , 50 f ; age = 70.6 7.3 yrs ) were randomized to hspt at 40% one - repetition maximum ( 1rm ) ( hspt : n = 25 ; 3 sets of 1214 repetitions ) , slow - speed streng...
membranous glomerulonephritis ( mgn ) is the most important cause of nephrotic syndrome in adults . among patients > 60 years old , secondary mgn is more common , especially due to underlying malignancy . in 2009 , the m - type phospholipase a2 receptor ( pla2r ) was identified as the major podocyte antigen involve...
a 95-year - old woman was admitted to our hospital for evaluation of bilateral lower - limb edema persisting for 3 months . serum creatinine was 1.55 mg / dl , and urinary protein excretion was 9.1 g / day . renal biopsy revealed stage 1 membranous glomerulonephritis ( mgn ) with immunoglobulin g4-dominant staining...