Subset (2)

section · 133k rows

Split (3)

train · 120k rows

article stringlengths 0 826k	abstract stringlengths 174 4.34k
in an effort to develop effective vaccines against pathogens that severely affect humans , the concept of original antigenic sin ( oas ) has become a guiding light , making sense of baffling observations on the infection profiles of foreign pathogens and vaccine efficacies in humans . oas was first described by daven...	the human immune system has evolved to fight against foreign pathogens . it plays a central role in the body 's defense mechanism . however , the immune memory geared to fight off a previously recognized pathogen , tends to remember an original form of the pathogen when a variant form subsequently invades . this ...
when there is a mass such as a congenital anomaly or lymphangioma in the oral cavity of a pediatric patient , the airway can be compressed and intubation can be difficult . wa , usa ) is a laryngoscope with a micro - video camera and a 7-inch display monitor . it can be used in conventional intubation , but is most...	lymphangioma is a congenital malformation of lymphatic system and often involves the oral cavity . when lymphangioma is located on the mouth floor and enlarges , it can compress the airway and make intubation difficult . the glidescope video laryngoscope is sometimes used in routine intubation , but is most commonl...
double - j ( dj ) stents are used to drain urine from the kidney to the bladder and are effective in managing and preventing upper urinary tract ( ut ) obstruction in various urological conditions ( 1 ) . the most common indication of stenting is to prevent and relieve upper ut obstruction ( 2 , 3 ) . the known com...	double - j ( dj ) stents are the main tools used in urological practice for prevention and treatment of obstruction . stenting is also mandatory after complicated ureteroscopy or tul ( transureteral lithotripsy ) . known complications are upper migration of dj stents into the kidney and lower migration to the bladd...
	as part of our ongoing effort to expand the scope of cross - coupling reactions of alkyl electrophiles , we have pursued a strategy wherein the nucleophilic coupling partner includes a pendant olefin ; after transmetalation by such a substrate , if -migratory insertion proceeds faster than direct cross - coup...
malaria is a major public health problem with 300500 million new infections each year and an estimated 584,000 deaths from malaria were reported worldwide , with most ( 90% ) of the deaths occurring in africa . the decline of susceptibility of plasmodium falciparum to chloroquine and sulfadoxine - pyrimethamine in ma...	aim . to assess the self - medication against malaria infection in population of congolese students in kinshasa , democratic republic of congo ( drc ) . methods . a cross - sectional study was carried out in university of kinshasa , kinshasa , democratic republic of congo . medical records of all students with ma...
today , deep - water benthic habitats , i.e. those areas below the euphotic zone at a water depth of more than c. 200 m , account for more than 65% of the earth 's surface . however , these regions are much more difficult to access than shallow waters and thus , despite considerable effort during the past decades , ...	a bivalve assemblage from the lower cretaceous puez formation at the type locality , piz de puez ( dolomites , south tyrol , northern italy ) is described . given the large amount of sedimentary rock screened during the course of this study , the < 50 bivalves examined here , although occurring in very low abundance ...
in the movie contagion , laurence fishburne ( as ellis cheever ) , chief of special pathogens at the centers for disease control , tells jennifer ehle ( as ally hextall ) , an epidemiological intelligence service officer coordinating research on the fictional henipavirus mev-1 , to move all research from bsl-3 ( biosaf...	abstractthe discussion of h5n1 influenza virus gain - of - function research has focused chiefly on its risk - to - benefit ratio . another key component of risk is the level of containment employed . work is more expensive and less efficient when pursued at biosafety level 4 ( bsl-4 ) than at bsl-3 or at bsl-3 as ...
female urethral cancer ( uca ) is a rare malignancy ; it accounts for approximately 1% of all female urological cancer ( 1 ) . initial signs of uca , such as voiding symptoms and bloody spotting , are ignored in most patients with female uca because they are not pathognomonic . in fact , voiding symptoms and blo...	the aim of this study was to evaluate female urethral cancer ( uca ) patients treated and followed - up during a time period spanning more than 20 yr at single institution in korea . we reviewed medical records of 21 consecutive patients diagnosed with female uca at our institution between 1991 and 2012 . after exc...
gastric cancer is the fifth most common cancer among males and seventh most common cancer among females in india . the aggressiveness of the disease and need for improvement in therapeutic options is discerned by the fact the gastric cancer is the second most common cause of cancer death globally . the high inciden...	the incidence of gastric cancer in india is low compared to developed countries , though there are certain geographical areas ( southern part and northeastern states of country ) where the incidence is comparable to high - incidence areas of world . despite the large number of patients being treated for gastric cancer ...
the dengue virus is a single - stranded rna virus of the flaviviridae family causing dengue fever and dengue hemorrhagic fever . dengue encephalopathy is usually secondary to multisystem derangement like shock , hepatitis , coagulopathy , and concurrent bacterial infection . dengue encephalitis is a different entit...	we report a case of dengue fever with features of encephalitis . the diagnosis of dengue was confirmed by the serum antibodies to dengue and the presence of a dengue antigen in the cerebrospinal fluid . this patient had characteristic magnetic resonance imaging brain findings , mainly involving the bilateral thalam...
lipomas are the most common benign mesenchymal tumors developing in any location where fat is normally present . the etiology of lipomas is uncertain and the tumors mainly affect the region of the trunk , shoulders , neck , and axilla . involvement of the oral cavity is rare , with lipomas corresponding to less tha...	the lipoma is a very common benign tumor of adipose tissue , but its presence in the oral and oropharyngeal region is relatively uncommon . fibrolipoma , a histological variant of lipoma , mostly affect the buccal mucosa and causes functional and cosmetic disabilities . hence , accurate histopathological examinatio...
author do not report any financial or personal links with other persons or organizations , which might affect negatively the content of this publication and/or claim authorship rights to this publication .	it is estimated that 3.4% of patients qualified for cholecystectomy due to cholelithiasis have a coexisting choledocholithiasis . for decades , endoscopic ascending retrograde cholangiopancreatography has been the golden diagnostic standard in cases of suspected choledocholithiasis . the method is associated with a...
in cross - sectional analyses , we evaluated the likelihood that americans with previously unrecognized pre - diabetes would meet ada consensus panel recommendations for consideration of metformin in addition to change in lifestyle . criteria for consideration of metformin included the presence of both ifg and igt , ...	objectiveto determine the proportion of the american population who would merit metformin treatment , according to recent american diabetes association ( ada ) consensus panel recommendations to prevent or delay the development of diabetes.research design and methodsrisk factors were evaluated in 1,581 screening for im...
several randomized controlled trials have demonstrated a survival benefit with an implantable cardioverter - defibrillator ( icd ) among patients who are at high risk for sudden cardiac death in primary prevention settings . it is of major importance to identify patients who will benefit from icd implantation and gen...	the purpose of this study was to evaluate predictors of appropriate therapy in patients with implantable cardioverter - defibrillators ( icd ) for primary prevention of sudden cardiac death . a retrospective cohort of 321 patients with systolic heart failure undergoing icd placement for primary prevention of sudden c...
living donor liver transplants ( ldlt ) are associated with a higher rate of biliary complications than deceased donor liver transplants ( ddlt ) . biliary leaks and subsequent biliary strictures have been reported to occur in up to 30% of the patients undergoing ldlt . management of biliary complications involves ...	aim : to retrospectively analyze the percutaneous transhepatic techniques and their outcome in the management of biliary strictures in living donor liver transplant ( ldlt ) recipients.materials and methods : we retrieved the hospital records of 400 ldlt recipients between 2007 and 2015 and identified 45 patients with ...
the conventional surgery for curative treatment of distal gastric cancer is resection of the distal stomach with all of the greater omentum and lesser omentum . but a less invasive procedure such as laparoscopic - assisted distal gastrectomy ( ladg ) has become more popular as the detection rate of early gastric canc...	omental infarction occurring after open and laparoscopic - assisted distal gastrectomy with partial omentectomy for gastric cancer was a very rare disease in the past , but its incidence has increased as more partial omentectomies are now being performed . but there are few case reports or radiologic studies on its i...
diabetes is the most frequent endocrine disease in developed countries and one of the most common noncommunicable diseases ( ncds ) globally , estimated to have affected more than 371 million people in 2012 and projected to affect 552 million by 2030 . it is the fourth or fifth leading cause of death worldwide with 4...	purpose . the pathogenesis of diabetic retinopathy ( dr ) is insufficiently understood but may possibly involve chronic , low - grade inflammation . the aim of this cross - sectional study was to investigate the relationship between inflammatory and haemostatic markers , other markers of endothelial dysfunction and...
metabolic syndrome ( ms ) is a disorder comprised of a combination of glucose intolerance , hypertension , dyslipidemia , and visceral fat accumulation , which promotes the development of cardiovascular diseases and atherosclerosis [ 1 , 2 ] . inflammation , demonstrated primarily by elevated levels of serum c - reac...	metabolic syndrome ( ms ) is a cluster of glucose intolerance , hypertension , and dyslipidemia with visceral fat accumulation . this study was undertaken to assess which components of metabolic syndrome ( ms ) , including uric acid and proinflammatory markers , are related to adiponectin levels in overweight and obe...
the egg batches of h. nigrescens were collected in niigata prefecture , japan , in april 2012 . arrows indicate the level of the line between epaxial muscles and hypaxial muscles . a : st 38 , b : st 50 , c : st 58 , d : st 63a , e : st 66 , f : st 68 . scale bar=5 mm . and table 1table 1.specimens of hynobius nigr...	we investigated ontogenetic changes in the trunk muscles of the japanese black salamander ( hynobius nigrescens ) before , during and after metamorphosis . given that amphibians change their locomotive patterns with metamorphosis , we hypothesized that they may also change the structure of their trunk muscles . the t...
although breast cancer is the most common cancer among women in both developed and developing countries , it has a higher survival rate than other cancers ( 15 ) . improvements in the breast cancer survival rate over recent decades have been attributed to progressive developments in early diagnosis and use of adjuvan...	introductioncoping with breast cancer is an important health issue that results in adjustments to the disease in survivors . the present systematic review aims to synthesize the evidence about the coping strategies used by women who are primary breast cancer survivors to adjust to their new situations in their lives....
nonmuscle - invasive bladder cancer seldom shows distant metastasis . in addition , it is extremely rare for bladder cancer staged as ta under the international union against cancer guidelines to result in distant metastasis . we present the case of a patient with a distant pulmonary metastasis of ta bladder cancer ;...	a 66-year - old man with a history of multiple transurethral resections for recurrent bladder tumors , staged as ta according to the international union against cancer staging guidelines , presented with a complaint of dry cough . a round nodule with a diameter of 7.5 cm was detected in the lung by chest computed tom...
during recent decades methicillin - resistant staphylococcus aureus ( mrsa ) have emerged as human nosocomial pathogens throughout the world . mrsa were found to colonize and infect various animal species comprising horses [ 24 ] , cows , dogs and cats [ 6 , 7 ] , rabbits and other companion animals . a special f...	the aim of this study was to evaluate the prevalence and molecular characteristics of methicillin - resistant staphylococcus aureus ( mrsa ) among pigs and estimate the impact of this animal reservoir on human healthcare . nasal swabs were derived from 1,600 pigs at 40 german farms . the mrsa were characterized usi...
	within influenza viral particles , the intricate balance between host cell binding and sialic acid receptor destruction is carefully maintained by the hemagglutinin ( ha ) and neuraminidase ( na ) glycoproteins , respectively . a major outstanding question in influenza biology is the function of a secondary sialic ac...
hyper - immunoglobulin m syndrome ( higm ) is a rare heterogeneous group of disorders , 70% of which are due to cd40-ligand deficiency . these patients are susceptible to recurrent sinopulmonary infections and opportunistic infections , especially pneumocystis jiroveci pneumonia . bronchiectasis is characterized by...	the x - linked hyper - immunoglobulin m syndrome ( higm-1 ) is a rare genetic disorder characterized by elevated serum igm levels and low to undetectable levels of serum igg , iga and ige . these patients characteristically present with recurrent sinopulmonary infections and recurrent diarrhea . they also have high...
	the intestinal absorption of the nephrotoxic environmental pollutant cadmium increases markedly when iron stores are depleted . this may be mediated by an up regulation of the recently identified mucosal transporter dmt1 ( nramp2 or dct1 ) for divalent cations . we tested whether the highly increased iron absorption ...
excessive sweating is a medical condition in which a person sweats much more than needed . the medical name of this disorder is hyperhidrosis known as a common dermal problem that affects people of all ages and leads to negative impact on the quality of life . during the last decades , several studies have shown that...	background : excessive sweating is a medical condition in which a person sweats much more than needed . the medical name of this disorder is hyperhidrosis known as a common dermal problem that affects people of all ages and leads to negative impact on the quality of life . during the last decades , several studies ha...
paraneoplastic syndromes ( ps ) represent a heterogeneous group of disorders that reflect the remote effects of cancer arising in any specific organ system . some ps affect the nervous system and may precede the detection of the actual cancer by months or even years ; they can also be indicative for the specific site...	we report a 66-year - old woman with slowly progressive ataxia due to cerebellar atrophy . imaging studies revealed multiple lesions in both the lungs and dorsal subpleural space . a biopsy identified the lesions as metastases of a low - grade endometrial stromal sarcoma containing sex - cord elements . the histo...
. they can be either pedunculated or sessile and are more common in the extremities . we present a case of 18 year female , who came with a swelling in right groin since 2 years which was diagnosed to be osteochondroma on x - ray and magnetic resonance imaging . excision biopsy was done as the patient wanted it to ...	introduction : osteochondroma are benign neoplasms which arise from small cartilage nodules within the periosteum . they can be either pedunculated or sessile and are more common in the extremities . they rarely develop in bones like scapula , feet , hands and pelvis . management of the lesion is by en - bloc exc...
as demand for food and energy grows , innovative ways to meet demand while enhancing environmental quality will be needed . anaerobic digesters ( ads ) can produce renewable energy from livestock manure , prevent the release of methane , and reduce air and water pollution , and digested manure can be applied to crops...	livestock husbandry in the u.s . significantly contributes to many environmental problems , including the release of methane , a potent greenhouse gas ( ghg ) . anaerobic digesters ( ads ) break down organic wastes using bacteria that produce methane , which can be collected and combusted to generate electricity . ...
strabismus is an important medical condition with a prevalence ranging between 2% and 4% in the general population , which affects the population and causes severe complications.13 in most forms of strabismus , patients motor fusion mechanisms are anomalous or are inadequate for the maintenance of ocular alignment . ...	purposeto compare four stereo tests ( lang i , lang ii , titmus , and tno ) and assess their effectiveness . the main focus of this study is to identify the most useful stereo test as a challenging tool in the screening of strabismus.patients and methodsa total of 143 caucasian subjects , 74 males ( 52% ) and 69 female...
etec , the causative agent of travelers ' diarrhea , is the most common bacterial diarrheal disease of children in latin america , asia and africa , and it is contracted upon ingestion of contaminated food or water . it is estimated that this disease is responsible for 400 million cases annually resulting in 300 000 d...	to date , efforts to treat autoimmune diseases have primarily focused on the disease symptoms rather than on the cause of the disease . in large part , this is attributed to not knowing the responsible auto - antigens ( auto - ags ) for driving the self - reactivity coupled with the poor success of treating autoimmune ...
the type 1 boston keratoprosthesis ( kpro ) is a poly ( methyl methacrylate ) device that has gained acceptance in many types of end - stage corneal diseases as a viable surgical option.13 the kpro is assembled using a carrier donor tissue , and its optics afford excellent visual acuity and field of vision4 assuming th...	the type 1 boston keratoprosthesis preparation requires a 3-mm central punch and an 8.5 mm or larger punch in the carrier tissue . these punches are ideally concentric , but we have found difficulty in achieving concentric punches when the larger punch is performed first . we present a modification in the preparati...
	values of ( kcat / km)gap for triosephosphate isomerase - catalyzed reactions of ( r)-glyceraldehyde 3-phosphate and kcat / khpikga for reactions of the substrate pieces glycolaldehyde and hpo32 have been determined for wild - type and the following tim mutants : i172v , i172a , l232a , and p168a ( tim from t...
the rate of end - stage failure of several vital organs ( e.g. , kidneys , liver , heart , and lungs ) is increasing expeditiously due to scientific advancements and the ability to sustain brain dead patients over a long period of time ( 1 ) . organ transplantation is known as the treatment of choice for patients wit...	introductionorgan transplantation is the treatment of choice for some diseases . however , the need for cadaveric organ donation has either plateaued or is on a decreasing trend in some countries , especially in developed ones . in this study , we aimed to identify the barriers to organ donation in brain dead patie...
kimura disease ( kd ) presents as a subcutaneous mass , most frequently occurring in the head and neck regions . the histological characteristics of the disease are hyperplastic lymphoid tissue that contains well - developed lymphoid follicles , marked infiltration of eosinophils , vascular proliferation , and fibros...	kimura disease ( kd ) is an eosinophilic , granulomatous , benign , chronic inflammatory disease with an unknown etiology . a 33-year - old woman visited our hospital because of a palpable , left subclavian mass , a left scapulo - anterior pseudoaneurysm , and nephrotic syndrome . her subclavian lymph node biopsy e...
the use of the waterpipe , or shisha , for smoking tobacco is an old tradition in the eastern mediterranean region that goes back centuries . this habit is relatively rare in singapore , a country with a predominantly chinese population . carbon monoxide ( co ) poisoning can be notoriously deceptive and non - speci...	carbon monoxide poisoning has been reported as a result of exposure to various sources of smoke , such as car exhaust fumes , home water heaters and tobacco smoke . we describe a case of symptomatic , moderately severe carbon monoxide ( co ) poisoning in a young mediterranean man after smoking a waterpipe , or shisha...
lichen planus pigmentosus ( lpp ) , an uncommon variant of lp , is characterized by mottled or reticulated hyperpigmented , dark brown macules in sun - exposed areas and flexural folds . the histopathologic findings of lpp consist of hyperkeratosis , atrophic epidermis with vacuolar alteration of the basal cell layer...	we report two cases of lichen planus pigmentosus ( lpp ) that developed in a unilateral linear pattern . the patients presented with unilateral linear brown macules on the extremities . skin biopsy showed orthokeratosis , basal hydropic degeneration with scarce lymphohistiocytic infiltrates , and numerous melanophage...
crimean congo hemorrhagic fever ( cchf ) is a viral disease with approximate mortality rate of 30% in humans ( ergonul 2006 ) . the disease can be transmitted via contact with blood or secretions of infected animals and tick bite or manipulation and squishing of cchf infected ticks . human to human transmission i.e. ...	background : crimean - congo hemorrhagic fever ( cchf ) is a feverous and hemorrhagic disease endemic in some parts of iran and caused by an arbovirus related to bunyaviridae family and nairovirusgenus . the main virus reservoir in the nature is ticks , however small vertebrates and a wide range of domestic and wild ...
futsal has been growing as a relatively new sport since fifa standardised the regulations and international competitions ( i.e. , the first world championship was played in 1989 , rotterdam , the netherlands ) . however , from a scientific perspective , there is a lack of research in futsal , in particular when compa...	abstractthe aim of this study was to identify which variables were the best predictors of success in futsal ball possession when controlling for space and task related indicators , situational variables and the participation of the goalkeeper as a regular field player or not ( 5 vs. 4 or 4 vs. 4 ) . the sample consis...
this paper focuses on estimates of the australian population 's ( including women of child bearing age , the target group for folic acid fortification ) intake of folic acid from voluntary and mandatory fortified foods , and not their intake of total dietary folate from all foods consumed . folic acid as used in this...	mandatory folic acid fortification of wheat flour for making bread was implemented in australia in september 2009 , to improve the dietary folate status of women of child - bearing age , and help reduce the incidence of neural tube defects in the population . this paper presents estimates of folic acid intake in the ...
micro- and nanoscale photonic devices require miniaturized glass - based photonic components . in this context , silica nanofibers have a great potential as low - loss waveguides for nano - optics and microphotonics applications . the large tensile strength of these fibers allows for the development of micro- and n...	we report the unique growth of nanofibers in silica and borosilicate glass using femtosecond laser radiation at 8 mhz repetition rate and a pulse width of 214 fs in air at atmospheric pressure . the nanofibers are grown perpendicular to the substrate surface from the molten material in laser - drilled microvias where...
increasing longevity is one of the great achievements of our civilization , but it has also given rise to discussion about good and successful aging . the concept of successful aging has attracted much debate , but there is still no universally accepted definition or standard measurement tool for it . the encyclope...	objectives . this study was designed ( 1 ) to estimate the prevalence of successful aging among nonagenarians based on six different models and ( 2 ) to investigate whether successful aging is associated with socio - demographic factors . methods . a mailed survey was conducted with people aged 90 + in tampere in 2...
the ncic clinical trials group ma.17 study was a prospective , randomized , double - blind , placebo - controlled , phase iii trial of letrozole as extended adjuvant therapy for 5 years in postmenopausal breast cancer patients who remained disease - free after having completed approximately 5 years of standard adjuvant...	backgroundbiomarkers to optimize extended adjuvant endocrine therapy for women with estrogen receptor ( er)positive breast cancer are limited . the hoxb13/il17br ( h / i ) biomarker predicts recurrence risk in er - positive , lymph node negative breast cancer patients . h / i was evaluated in ma.17 trial for progn...
the essential features of the olmsted county , minnesota , usa , impaired glycemia ( oc ig ) survey were identification of persons with ig and non - ig in local population - based medical and laboratory registries , obtaining consent by letter , assessing their glycemia status ( non - ig , ig , and new diabetes ) at st...	objectiveto test whether diabetic polyneuropathies ( dpns ) , retinopathy , or nephropathy is more prevalent in subjects with impaired glycemia ( ig ) ( abnormality of impaired fasting glucose [ ifg ] , impaired glucose tolerance [ igt ] , or impaired hba1c [ ia1c ] ) than in healthy subjects ( non - ig).research desig...
according to ims institute for healthcare informatics estimates , health care costs caused by improper and unnecessary use of medicines exceeded $ 200 billion in 2012 ( ims institute for healthcare informatics , 2013 ) . in 2013 , the estimated health care expenditures related to potentially inappropriate medications...	objective : this study aims to examine potentially inappropriate medication ( pim ) prevalence and factors that affect the use of pims in a military treatment facility . method : admission and discharge medication lists of 60 patients aged 65 years were retrospectively reviewed by a clinical pharmacist and a member of ...
a 31-year - old female patient consulted to our outpatient clinic because of a mass protruding from her right nipple . on her breast examination , an 8 mm prolapsed mass was seen on the right breast areola ( figure 1 ) . during physical examination any abnormality was not detected on other parts of the breast , and h...	intraductal papillomas ( ip ) are benign papillary lesions caused by proliferation of mammary ductal epithelium . ip occurs in the breast tissue . prolapse of ip from nipple can be rarely seen . ips are generally treated with total excision . a 31-year - old female patient was admitted to our clinic because of ...
malignancies of the thyroid gland are relatively rare worldwide , but incidence has steadily increased over the last few decades . the majority of thyroid cancers are differentiated carcinomas of the papillary or of follicular type , which typically have a good prognosis and highest cure rate . here , we report a cas...	malignancies of the thyroid gland has steadily increased over the last few decades , out of which mostly are differentiated carcinomas of the papillary or of follicular type , have a good prognosis and highest cure rate if treatment commences early . here , we report a case of an 18-years - old boy with a huge multin...
in companion animals , the healing of large skin defects resulted from traumatic accidents can be challenging to treat since they need a complex management consisting of accurate debridement of damaged and necrotic tissues , local and/or systemic infection control , protection of the underlying tissues and induction of...	key clinical messageextensive full - thickness skin wounds are quite common in domestic animals . in these report , following the failure of reconstructive surgery , adipose tissue - derived mesenchymal stem cells , and platelet - rich plasma were successfully used in a dog to improve speed and quality of skin tissue...
the papillomaviruses ( pvs ) are viruses that require the environment of a differentiating epithelium for their replication cycle . pvs infect mammals , including man , and are related to development of benign lesions that can progress to cancer . uterine cervical cancer , the second most frequently occurring cance...	the majority of malignant cells present genetic instability with chromosome number changes plus segmental defects : these changes involve intact chromosomes and breakage - induced alterations . some pathways of chromosomal instability have been proposed as random breakage , telomere fusion , and centromere fission . ...
the complications related to drug abuse such as myocardial insufficiency , myocardial infarction , endocarditis , myocarditis , aortic dissection , neurologic damage , ischemic colitis and renal failure are known , but have been reported very rarely . amongst the illicit drugs , cocaine , amphetamines and cannabis have...	amongst the illicit drugs cocaine , amphetamines and cannabis have been studied and documented well to cause myocardial infarction by different mechanisms but there is very sparse data available on myocardial involvement after heroin abuse . we report a young man who developed acute myocardial injury after heroin inh...
hypothyroidism is a complex disorder characterized by an increase in body weight . about 1530% of hypothyroid patients are reported to be overweight and sufficient replacement therapy generally induces significant weight loss . however , 7% of the patients were observed to preserve their original weight in spite of...	aim . we aimed to observe the effects of l - thyroxine replacement therapy on body fat content determined with various anthropometric methods and a bioelectrical impedance analysis method in patients with hypothyroidism . methods . forty - two women with naive autoimmune hypothyroidism were included . also , 40 h...
diabetes especially diabetes mellitus ( dm ) has become a disease of concern for both developed and developing countries [ 1 , 2 ] . in adults , the prevalence of dm worldwide was estimated to be 8.3% in 2011 and is expected to rise to 9.9% by the year 2030 largely due to the global obesity epidemic and other factors...	type 2 diabetes mellitus ( type 2 dm ) has become a disease of public health concern worldwide . obesity and elevated blood pressure have been shown to be comorbidities of type 2 dm . in this cross - sectional study in tamale , ghana , we determined the prevalence of abdominal obesity among type 2 dm patients . fur...
patient 1 was a 60-year - old man who was hospitalized on 5 august 2013 , because of two weeks of fever , arthralgias and malaise . furthermore , no plasmodium parasite was observed on the giemsa stained blood smears obtained on the first day of hospitalization . the patient had a temperature of 38.5c , low platele...	babesiosis is a tick - borne , zoonotic disease caused by babesia spp . two cases of babesiosis were detected by nested polymerase chain reaction ( pcr ) in yunnan province , china , and further confirmed by molecular assay . the blood smears showed intraerythrocytic ring form and tetrads typical of small b. microt...
diabetes mellitus is one of the chronic metabolic diseases characterized by high blood glucose level , due to the absence of insulin and/or defect in insulin action . the chronic elevation of blood glucose level in diabetic patient leads to complications and failure of many organs in the body such as heart , kidney ,...	background : omentin is a newly identified adipokine that has beneficial influence against cardiovascular disorders . hence , considering the impact of anti - diabetic drug on omentin levels may provide an adjuvant strategy to protect diabetic patients against valuable clinical hazards.aim of the study : to investiga...
the total contamination of fukushima - daiichi nuclear power plant ( f1npp ) accident was about a tenth comparing to that of the chernobyl accident , and a hundred times to that of the windscale accident [ 1 , 2 ] . most of the radioactive materials dispersed to the pacific ocean by the dominant westerly wind occurri...	the fukushima daiichi nuclear power plant ( f1npp ) accident is an iaea level 7 event , the same as that of chernobyl , while the amount of radionuclides released is not comparable . radioactivity attributed to the f1npp accident was detected 250 km away from the f1npp . although we have not yet systematically stu...
microorganisms such as fungi , viruses and bacteria are recognized as biocontrol agents ( 1 ) . nematodes are a large group of parasites which cause serious economic and hygienic problems in plants , animals and humans . several programs are developed to minimize the unfavorable effects of gastrointestinal parasite...	background : biological control of parasitic nematodes by microorganisms is a promising approach to control such parasites . microorganisms such as fungi , viruses and bacteria are recognized as biocontrol agents of nematodes.objectives:the current study mainly aimed to evaluate the in vitro potential of various sapr...
all videos were viewed and included in subsequent analyses if tcg was discussed or shown . most of the search terms used in the current study were obtained from the orlando sentinel and additional terms commonly used in tcg research , including the following : the choking game ; space cowboy ; space monkey ; funky ch...	the choking game ( tcg ) is an adolescent activity in which asphyxiation is used to obtain a high , occasionally resulting in seizures or death . a plethora of tcg information is available through youtube , though this content has not been evaluated recently . the current study described tcg as portrayed in youtu...
due to ageing populations and increased survival rates from myocardial infarction , heart failure ( hf ) is now at epidemic levels in high - income countries [ 1 , 2 ] . as a result , the costs of caring for people with hf are very high and rising . over past decades , a primary strategy in reducing the personal and ...	to improve patient support , it is important to understand how people view and experience heart failure ( hf ) self - care . this systematic review of qualitative studies included all published studies that examine the influence of sex and gender on hf self - care . a systematic search was done for papers ( 1995201...
all tissues were obtained from north carolina eye bank donors without a clinical history of glaucoma or glaucoma - associated conditions , elevated iop , or the use of glaucoma medications or steroids . the ocular tissues were dissected out by the surgeon ( rra ) and immersed in rnalater ( ambion , waltham , ma , usa...	purposebecause micrornas ( mirnas ) have been associated with eye diseases , our study aims to profile ocular mirna expression in normal human ciliary body ( cb ) , cornea , and trabecular meshwork ( tm ) using mirna - seq to provide a foundation for better understanding of mirna function and disease involvement in the...
pregnancy is a transient condition , but when it is complicated by preeclampsia it has lasting effects on both the mother and the child . this paper describes the short- and long - term consequences of preeclampsia to both the mother and the child , with an emphasis on the children 's vulnerability to vascular diseas...	this paper reviews the literature pertaining to the impact of preeclampsia not only on the mother but particularly on the children . the review points to the higher blood pressure in children born to preeclamptic mothers compared to controls , their increased tendency to suffer strokes , the reduction in their cognit...
professor marthanda varma sankaran valiathan is currently chairman of the task force in ayurvedic biology of the department of science and technology and an honorary advisor , manipal university . earlier , he was professor of cardiac surgery and director of the sree chitra tirunal institute for medical sciences and ...	professor marthanda varma sankaran valiathan , fellow of the royal college of surgeons , ex president of the indian national science academy , is a reputed cardiac surgeon who made original contributions to cardiology and the development of medical technology . he is widely recognized for his role in pioneering the j...
lung carcinoma is the mostly frequently diagnosed cancer in the world and is also the most common cause of cancer deaths in males and females all over the world . female lung cancer , with mortality higher than that of the combined mortality from breast and colon / rectum cancer , accounted for 26% of the estimated c...	backgroundnon - small cell lung cancer ( nsclc ) accounts for approximately 80% of lung carcinoma cases , which becomes more and more important in the field of lung carcinoma as well as primary lung carcinoma in females.material/methodswe analyzed the medical history of 62 female nsclc patients . immunohistochemistry...
glucocorticoid ( gc ) excess , including cushing 's syndrome , is a common cause of secondary osteoporosis . several reports have confirmed the high prevalence of various degrees of osteopenia / osteoporosis in patients with hypercortisolism . the prevalence of osteopenia and osteoporosis in cushing 's syndrome is ...	glucocorticoid ( gc ) excess , including cushing 's syndrome , is a common cause of secondary osteoporosis . thirty to fifty percent of cushing 's syndrome patients experience non - traumatic fractures , which is often the presenting manifestation of cushing 's syndrome . however , there have been rare cases of cushi...
diabetes mellitus is an important public health issue due to its high prevalence and increased morbidity and mortality . cardiac injury is caused by coronary atherosclerosis and diabetes - related cardiomyopathy . as first reported by rubler et al . , diabetic cardiomyopathy is a single form of heart disease charac...	we evaluated the effects of a low intensity aerobic exercise protocol on cardiac remodeling and myocardial function in diabetic rats . wistar rats were assigned into four groups : sedentary control ( c - sed ) , exercised control ( c - ex ) , sedentary diabetes ( dm - sed ) , and exercised diabetes ( dm - ex ) . di...
intravenous ( iv ) induction during general anesthesia ( ga ) is common practice in modern anesthesia . avoidance of neuromuscular blocking ( nmb ) drugs is an unusual requirement , in surgical procedures that mandates no paralysis ( e.g. , selective nerve stimulation to aid in dissection ) , anticipated difficult...	background and aims : a target bispectral index ( bis ) value of 40 is considered adequate for depth of anesthesia , but no consensus exists regarding bis value for tracheal intubation without neuromuscular blocking drugs . the aim of this randomized , double - blinded study was to compare the total duration from sev...
eight male new zealand white rabbits , weighing approximately 3 kilograms each , were included in this study . these rabbits were anesthetized with an intravenous injection of ketamin ( 40 mg / kg ) and xylazine ( 5 mg / kg ) , and placed in the right decubitus position ; thus , allowing a retroperitoneal approach to...	objectiveto characterize the imaging features on gray - scale and contrast - enhanced color doppler us images which differentiate renal ischemia from renal infarction.materials and methodsthe segmental renal arteries of eight healthy rabbits were surgically ligated . in four of these rabbits , the ligated renal arter...
the seronegative spondyloarthopathies ( spa ) that include ankylosing spondylitis ( as ) , reactive arthritis , and arthritis associated with psoriasis or inflammatory bowel disease , and juvenile onset spondyloarthropathy , share certain common articular and peri - articular features that differ from rheumatoid arthri...	the seronegative spondyloarthopathies ( spa ) share certain common articular and peri - articular features that differ from rheumatoid arthritis ( ra ) and other forms of inflammatory arthritis . these include the tendency of the spas to involve the axial skeleton in addition to the diarthrodial joints , and the prom...
given the 1:500 prevalence of hypertrophic obstructive cardiomyopathy ( hocm ) in the general population , it may present to the anaesthesiologist more often than anticipated . we hereby describe how our anaesthetic technique ( general anaesthesia with peripheral nerve blocks ) for bilateral knee arthroplasty was wel...	this case report exemplifies how the anaesthetic technique of general anesthesia with continuous bilateral femoral nerve block for bilateral knee arthroplasty was well chosen for the management of perioperative complications in an elderly patient with hypertrophic obstructive cardiomyopathy ( hocm ) . a 69-year - old...
bladder cancer is the fifth most common malignancy in europe with more than 151,000 new cases diagnosed annually , accounting for 4.4% of all cancers excluding non - melanoma skin cancer . 70 to 80% of bladder tumors are classified as non - muscle invasive bladder cancer ( nmibc ) . it was repeatedly demonstrated t...	introductionone of the factors responsible for the risk of recurrence after complete transurethral resection of the bladder tumor ( turbt ) in patients with non - muscle invasive bladder cancer ( nmibc ) is the quality of surgery that may vary between individual surgeons . the aim of the study was to evaluate the imp...
studies suggest that localized renal cell carcinoma ( t12n0m0 ) is best treated by nephron - sparing surgery ( nss ) rather than by radical nephrectomy irrespective of the surgical approach . although the ideal outcome remains partial nephrectomy ( pn ) , patient characteristics , tumor radiologic features , surgeon ...	abstractthis study sought to evaluate the predictive value of the dap ( diameter - axial - polar ) nephrometry system on surgical outcomes following partial nephrectomy ( pn).this was a retrospective study of 237 patients who underwent open or minimally invasive pn for renal tumors at a single tertiary care center betw...
	tooth carving is an important practical preclinical exercise in the curriculum in indian dental education setup . it forms the basis of introduction to tooth anatomy , morphology and occlusion of primary and permanent teeth through practical approach . it requires enormous time and manpower to master the skill . ...
traumatic crown fractures , which are caused from dental injuries , are a serious dental public health problem.1 a majority of the crown fractures involve the maxillary incisors.2 today s dental patients are demanding a youthful , attractive smile.3 single - appointment direct restorations should ideally be restricted ...	coronal fractures of permanent dentition are the most frequent type of dental injury . if the original tooth fragment is retained following fracture , the natural tooth structures can be reattached using adhesive protocols . the development and use of fiber - reinforced composite root canal posts make possible of t...
every year between the 1200 to 1400 persons per million develop urinary calculosis with a male to female ratio of 3:1 ( 1 ) . urology is probably the oldest branch of surgery , knowing that one of the first operations was safe and resolve stone jammed on the outer opening of the urethra ( 2 ) . creation of stones i...	introduction : elimination of stone is determined by size and its localization . stone from the ureter in 80% of cases can be eliminated spontaneously . if the stone by its characteristics is not spontaneously eliminated , taken are further steps and therapeutic protocols to solve this problem.material and methods : ...
atherosclerosis is a common degenerative disorder , which is closely related to the aging process . because of the aging of the general population , atherosclerotic renal artery stenosis ( aras ) is anticipated to become increasingly prevalent over the coming decades . aras is a common cause of hypertension and chron...	abstractthe aim of this study was to investigate the risk factors associated with end - stage renal disease ( esrd ) in patients with atherosclerotic renal artery stenosis ( aras).information about the study participants was extracted from the national health insurance research database of taiwan for the years 1999 thr...
these extrahepatic lesions are most commonly found in the lungs , lymph nodes , and bones . there have been reports of extrahepatic lesions found in urogenital sites , such as the kidneys , testes , and bladder [ 24 ] . we encountered a patient with a metastatic hcc lesion presenting as a tender right inguinal mass...	most spermatic cord masses are benign , and malignant spermatic cord tumors are uncommon . spermatic cord metastases originating from hepatocellular carcinoma ( hcc ) have not been previously reported in the english language literature as determined by a pubmed search . we report a male patient who presented with a...
severe growth hormone deficiency ( ghd ) in adults can give rise to several abnormalities . a growing recognition of this clinical syndrome in the last 20 years has led to the therapeutic use of growth hormone ( gh ) replacement in adults with severe ghd . this treatment is now available in approximately 80 countri...	adult growth hormone ( gh ) deficiency is a recognised syndrome associated with adverse phenotypic , metabolic , and quality - of - life features which improve in many patients when gh is substituted . the appropriate selection of patients at risk of growth hormone deficiency ( ghd ) is the crucial first step in arri...
to detect bim deletion polymorphism , we performed two types of polymerase chain reaction ( pcr ) analysis , according to the method of ng et al . in brief , we used a single primer set that contains the deletion area in intron 2 and two separate primer sets designed for wild - type and deletion alleles . the dna was...	background : germline alterations in the proapoptotic protein bcl-2like 11 ( bim ) can have a crucial role in tumor response to treatment . to determine the clinical utility of detecting bim deletion polymorphism in non small - cell lung cancer positive for epidermal growth factor receptor ( egfr ) mutation , we exami...
contrast - enhanced computed tomography colonography ( ce - ctc ) is the best technique for colorectal cancer sites and staging ( 12 ) , as well as to diagnose synchronous colonic lesions ( 3 ) in patients with obstructing cancers . ce - ctc is also useful to preoperatively evaluate others colorectal diseases , such ...	contrast - enhanced computed tomography colonography ( ce - ctc ) is a useful guide for the laparoscopic surgeon to avoid incorrectly removing the colonic segment and the failure to diagnose of synchronous colonic and extra - colonic lesions . lymph node dissection and vessel ligation under a laparoscopic approach ca...
primary hyperparathyroidism ( php ) is a rare life - threatening condition that can present during the pregnancy . most of the cases are due to parathyroid adenoma , but rarely parathyroid carcinoma may be the cause of php . diagnosis can be difficult to establish during the pregnancy , given the non - specific sym...	incidence of primary hyperparathyroidism ( php ) in pregnancy is 8/100,000 population / year with less than 200 cases reported . physiological changes associated with pregnancy make a diagnosis of php difficult and 80% are asymptomatic . high index of suspicion is required as physiological hypocalcemia related to h...
unilocular adipocytes are the principal component of white adipose tissue and have a classical role in the regulation of triglycerides and fatty acid accumulation during energy expenditure and deprivation 1 - 2 . the regulation of adipocyte differentiation is controlled by several factors , includin...	age - associated thymic involution is characterized by decreased thymopoiesis , adipocyte deposition and changes in the expression of various thymic microenvironmental factors . in this work , we characterized the distribution of fat - storing cells within the aging thymus . we found an increas...
a 24-year - old woman with mild pre - eclampsia was admitted for induction of labor under normal - term labor after 40 weeks gestation . ten days before her admission she was admitted for 6 days for mild hypertension and moderate edema of her legs . her blood pressure at the time of admission was 152/82 mm hg and h...	we report a complication related to epidural analgesia for delivery in a 24- year - old woman who was admitted with mild pre - eclampsia and for induction of labor . at the first postpartum day she developed a postdural puncture headache , which was unresponsive to conservative measures . on the fifth day an epidural...
resin - bonded fixed partial dentures ( fpds ) are inexpensive and there are more conservative treatment options for replacing missing teeth [ 1 , 2 ] . metal resin - bonded fpds continue to decrease demand because of the existing several disadvantages . while metal substrate is durable and stiff , it has considera...	objective : color match between fiber - reinforced composite ( frc ) restorations and teeth is an imperative factor in esthetic dentistry . the purpose of this study is to evaluate the influence of veneering composites and fibers on the color change of frc restorations.materials and methods : glass and polyethylene f...
initially we performed a pilot study with a yorkshire pig model , but because thin - section ct showed that the bronchi of this animal were relatively thick - walled and small - calibered , and the response to airway stimulating agents was thus minimally visible , the model was rejected as unsuitable . these animals ...	objectiveto determine the extent to which thin - section and volumetric three - dimensional ct can depict airway reactivity to bronchostimulator , and to assess the effect of different airway sizes on the degree of reactivity.materials and methodsin eight dogs , thin - section ct scans were obtained before and after th...
papillary lesions of the breast include benign ( papilloma ) as well as malignant ( papillary carcinoma ) entities . both the ends of the spectrum are characterized by the presence of fibrovascular cores lined by epithelial proliferation with varying degrees of atypia . though a definite diagnosis of the nature of ...	papillary lesions of the breast pose diagnostic challenges on aspiration cytology due to overlapping features of benign and malignant entities . accurate cytologic diagnosis of papillary breast carcinoma can not usually be made pre - operatively . we present the case of an adult female who underwent fine - needle a...
understanding the rules that govern protein folding is one of the great challenges of molecular biology . studies of protein folding , combining experiment and simulation , have led to a solid understanding of the physical process of folding and the forces that stabilize proteins . the last 10 years have witnessed ...	we have developed a new database that collects all protein folding data into a single , easily accessible public resource . the protein folding database ( pfd ) contains annotated structural , methodological , kinetic and thermodynamic data for more than 50 proteins , from 39 families . a user - friendly web interf...
the impetus to frame a new area of physiology often arises at the interface of existing fields of inquiry . as prime examples , neuroendocrinology emerged when nerve endings in the hypothalamus , near the base of the brain , were observed to release hormones that cue the anterior pituitary to regulate an array of end...	biofield physiology is proposed as an overarching descriptor for the electromagnetic , biophotonic , and other types of spatially - distributed fields that living systems generate and respond to as integral aspects of cellular , tissue , and whole organism self - regulation and organization . medical physiology , cel...
coexistence of systemic lupus erythematosus and vitiligo has been infrequently reported . however , cases of vitiligo coexisting with discoid lupus erythematosus ( dle ) have been much rarer . this is an important consideration as the presence of one disorder may affect the therapy of the second and require detail cl...	there have been rare published cases of discoid lupus erythematosus ( dle ) with other autoimmune cutaneous and systemic disorders . we describe a 36 years old female patient with dle lesions on the face and hands with coexistence of lip - tip vitiligo and hypothyroidism . we discuss how the treatment has to be mod...
in global era and resulting from asean economic community ( aec ) s policy to induce rapid economic , social , and environmental changes . these changes led to the change of employee system , especially , thai immigrant employees in asia . the characteristic of employees movement among all employees in many countri...	background : the aim of this study was to verify a path model of job stress using thai-jcq.methods:the population of this cross - sectional study was 800 immigrant employees in the central region of thailand in 2015 by stratified random sampling . instruments used both the applied and standard questionnaires . job ...
the mammalian target - of - rapamycin inhibitor ( mtor ) everolimus has been licensed in europe since 2004 for the prevention of organ rejection in adult patients at low to moderate immunological risk receiving an allogeneic kidney , liver or heart transplant . it was developed to improve the pharmacokinetics of the ...	the evidence base relating to the use of everolimus in heart transplantation has expanded considerably in recent years , providing clinically relevant information regarding its use in clinical practice . unless there are special considerations to take into account , all de novo heart transplant patients can be regard...
older people 's participation in leisure activities , such as involvement in cultural , social , and physical activities , is known to be positively associated with health and survival . it is therefore important to improve the understanding of the risk factors that might cause a decline in such participation . acc...	objectives . this study aims to investigate the impact of medical conditions , mobility difficulties , and activity limitations on older people 's engagement in leisure activities . methods . the analyses are based on a cross regional survey carried out in 2010 in the bothnia region ( northern sweden and western finl...
multidrug resistance ( mdr ) is one of the main causes of the failure of cancer chemotherapy . one of the major mechanisms of drug resistance is mediated by overexpression of p - glycoprotein ( p - gp , abcb1 , mdr1 ) . p - gp is a membrane - bound protein that functions as a drug efflux transporter . thi...	acquired drug resistance in cancer continues to be a challenge in cancer therapy , in part due to overexpression of the drug efflux transporter p - glycoprotein ( p - gp , mdr1 , abcb1 ) . nsc73306 is a thiosemicarbazone compound that displays greater toxicity against cells expressing functional p - gp than...
increase in the prevalence of neurodegenerative diseases and neural damage has caused the scientists to search for various approaches such as cell therapy to improve the neurogenesis techniques . a lot of investigations confirmed the presence of adult stem cells in various tissues including breast milk . breast mil...	objectives . human breast milk contains a heterogeneous population of cells that have the potential to provide a noninvasive source of cells for cell therapy in many neurodegenerative diseases without any ethical concern . the objectives of this study were to differentiate the breast milk - derived stem cells ( bmdsc...
the morphology of the human face varies with individuals and even more with races and ethnic group.1 the identification of aesthetic facial qualities began with ancient civilizations such as egyptians and greeks , who captured their ideals of facial beauty in artform.2 some of the classical greek canons of facial propo...	background : a carefully performed facial analysis can serve as a strong foundation for successful facial reconstructive and plastic surgeries , rhinoplasty or orthodontics.aim:the purpose of this study is to determine the facial features and qualities of the igbo nigerian adult male using photometry.materials and meth...
we present a case of an 80-year - old gentleman presenting to the emergency department with a swelling on the anterior abdominal wall in the right upper quadrant extending over the right costal margin . the swelling had developed spontaneously , was painless and increasing in size over two months . he had specifica...	abdominal wall abscess secondary to spontaneous cholecystocutaneous gallstone fistulation is an uncommon presentation of a rare pathological process . having been described relatively frequently in the 19th century , it is now much less common in the late 20th and early 21st century , probably due to earlier recognit...
pulmonary arteriovenous malformations ( pavms ) are unusual abnormalities of the pulmonary vasculature and are often associated with hereditary hemorrhagic telangiectasia ( hht ) ( 1 ) . they lead to a right - to - left shunt due to a direct connection between a pulmonary artery and a pulmonary vein . most of the c...	pulmonary arteriovenous malformations ( pavms ) are thin - walled aneurysms caused by abnormal communication between the pulmonary arteries and veins . migraine headaches are sometimes the presenting clinical manifestation of pavms . although embolotherapy , using detachable balloons or stainless steel coils , is gen...
cardiovascular diseases are the most important medical challenge worldwide including iran . 30% of the mortality and 10% of the global burden of diseases are attributed to cardiovascular diseases . myocardial infarction ( mi ) has the highest contribution among cardiovascular diseases in iran . in 2012 , only 4% of 4...	background : regarding failure to establish the statistical presuppositions for analysis of the data by conventional approaches , hierarchical structure of the data as well as the effect of higher - level variables , this study was conducted to determine the factors independently associated with hospital mortality due ...
we obtained tumor specimens from 231 patients with invasive breast carcinoma and from 200 matched preoperative plasma and tumor specimens from 90 patients with intraductal carcinoma who underwent surgical resection at samsung medical center from may 2002 through december 2004 . all of the tissues had been fixed in 10...	backgroundthe p16ink4a gene methylation has been reported to be a major tumorigenic mechanism.methodswe evaluated the methylation status of the p16ink4a genes in 231 invasive breast cancer and 90 intraductal carcinoma specimens using a methylation - specific polymerase chain reaction and p16 protein expression using im...
larvae of d. pini and n. sertifer were collected in northern italy . in detail , a total of 300 larvae of d. pini were collected on pinus sylvestris plants in 2007 , in two sampling sites in the municipalities of san martino in monte ( bolzano county ) and san dorligo ( trieste county ) della valle ( trento county ) ...	sawflies are important pests of various plant species . diprion pini ( l. ) and neodiprion sertifer ( geoffroy ) ( hymenoptera : diprionidae ) are two of the most important sawfly pests in italy , and both species are parasitized by the hymenopteran parasitoid dahlbominus fuscipennis ( zetterstedt ) . bacterial end...
twenty - three pgdm and eight women without any risk factors for type 2 diabetes serving as controls ( con ) were recruited from the outpatient service of the division of endocrinology and metabolism , department of internal medicine iii , medical university of vienna . gdm was diagnosed according to the criteria of ...	objectiveectopic lipid storage in muscle ( intramyocellular lipids [ imcl ] ) and liver ( hepatocellular lipids [ hcl ] ) coexists with impaired myocellular flux through atp synthase ( fatpase ) in certain cohorts with increased risk of type 2 diabetes . because women with a history of gestational diabetes mellitus ( p...
in the past decade , cardiac resynchronization therapy ( crt ) has become an important treatment option for symptomatic heart failure patients with reduced left ventricular ( lv ) ejection fraction and abnormal qrs duration mostly in the form of left bundle branch block ( lbbb ) . until recently , little was known abou...	cardiac resynchronization therapy ( crt ) aims to treat selected heart failure patients suffering from conduction abnormalities with left bundle branch block ( lbbb ) as the culprit disease . lbbb remained largely underinvestigated until it became apparent that the amount of response to crt was heterogeneous and that...

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.