Datasets:
ccdv
/
pubmed-summarization

Dataset card Data Studio Files
xet
 Community
8
article
stringlengths
0
826k
abstract
stringlengths
174
4.34k
autophagy is primarily a process that delivers cytoplasmic component to lysosomes for degradation . in its original definition , autophagocytosis and the latter heterophagocytosis , although these terms are less frequently used in modern parlance . the two processes can be distinguished according to what the ce...
salmonella enterica serovar typhimurium enter epithelial cells and take up residence there . within epithelial cells , a portion of the bacteria are surrounded by an autophagosome - like double - membrane structure , and they are still residing within the salmonella - containing vacuole ( scv ) . in this paper , we w...
spinal cord injury harms the physical and mental condition of patients and causes substantial economic burden to society . therefore , the prevention and treatment of spinal cord injury has become an important topic in medicine . scientists are investigating various avenues for treatment of spinal cord injury ; how...
backgroundspinal cord injury ( sci ) is the most critical complication of spinal injury . we aimed to identify differentially expressed genes ( degs ) and to find associated pathways that may function as targets for sci prognosis and therapy.material/methodsseven gene microarray expression profiles , downloaded from ...
we combined single molecule fluorescence resonance energy transfer ( smfret ) with single particle tracking in live cells to detect the in vivo conformation of individual proteins . we site - specifically labeled recombinant snare proteins with a fret donor and acceptor before microinjecting them into cultured cells ...
nonalcoholic fatty liver disease ( nafld ) affects 10% to 39% of the world population , 50% of diabetic patients , 57% to 74% of obese people , and up to 90% of the people with morbid obesity . its prevalence in obese adolescents is between 22.5% and 52.8% [ 1 , 2 ] . when not appropriately treated , nafld can prog...
objective . to assess the long - term effects of metformin in combination with lifestyle intervention and its association between insulin levels and the degree of steatosis at ultrasonography ( us ) in obese adolescents . methods . thirty - five postpubertal obese boys were randomized into two groups : one receivin...
the opercular syndrome , also known as foix - chavany - marie syndrome was first reported in 1926 , but was described first by magnus in 1837 . this term is usually used in relation to adults as it refers to damage that is acquired later in life . controversy exists in the literature regarding the nomenclature of ...
we present a 9-year - old boy with history of perinatal asphyxia and neonatal seizures ; who presented with delayed development of speech , with predominant dysarthria , dysphagia , and drooling of saliva and unable to protrude tongue along with delayed motor and mental milestones . he had complex partial seizures si...
laser - assisted in situ keratomileusis ( lasik ) is a widely used technique in refractive corneal surgery . many complications can occur during the preparation of the corneal flap , resulting in costly retreatments . a meta - analysis of 30 trials reported an incidence of 31% for intraoperative complications , of ...
purposefemtosecond lasers have become the standard for laser - assisted in situ keratomileusis ( lasik ) flap creation , but advanced mechanical microkeratomes are still an alternative , more cost - effective way to create the flap . the schwind carriazo - pendular microkeratome is one of the most commonly used micro...
our attempts to match memory performance across ieeg ( patient ) and fmri ( control ) groups ( by varying the number of sources , retention interval and encoding list length ; see methods ) were successful ( table 1 ) . a pr measure ( probability of correct minus probability of incorrect old decisions to studied...
in the endeavor to understand how our brains enable our multifaceted memories , much controversy surrounds the contributions of the hippocampus and perirhinal cortex ( prc ) . here we recorded functional magnetic resonance imaging ( fmri ) in healthy controls and intracranial electroencephalography ( eeg ) in patient...
in march 2014 , a 47-year - old woman was hospitalized at the bernhard nocht clinic ( hamburg , germany ) with chills , nausea , and fever ( temperature < 40c ) . the patient had a history of intravenous drug use ( cocaine and benzodiazepines ) and was currently enrolled in a methadone substitution program . she al...
we report a community - acquired bloodstream infection with acinteobacter ursingii in an hiv - negative woman who injected drugs . the infection was successfully treated with meropenem . species identification was performed by using matrix - assisted laser desorption / ionization time - of - flight mass spectrometr...
poland is a central european country with a population of more than 38 million inhabitants . from the beginning of the hiv epidemic in 1985 to 2004 , 8491 cases of hiv infection , 1421 aids cases , and 676 hiv / aids - associated deaths have been reported and confirmed . at the beginning of 2004 , more than 2000 hi...
summarybackgroundthis study was a retrospective analysis of drug resistance mutations among hiv-1 strains prevalent in silesia , poland , from the origin of the epidemic to 2004 . the investigations included both type and frequency of the reverse transcriptase inhibitors resistance mutations and estimation of the dru...
bipolar ii disorder is a chronic affective disorder characterised by episodes of major depression and hypomania . a hypomanic episode is characterised by symptoms such as flight of ideas , a decreased need for sleep , elation and talkativeness . these symptoms occur within an elevated or irritable mood which lasts ...
background : a number of studies have documented high levels of hypomanic symptoms in those diagnosed with depression , suggesting a potential misdiagnosis of bipolar disorder as unipolar depression . research suggests that undergraduate students have high levels of depression , but whether such misdiagnosis occurs i...
it is susceptible to neovascularization - inducing intervention , that is , microbial infection or ocular surface damage . the process of the new vessel formation in an injured cornea is orchestrated by a complex system of various growth factor signaling [ 15 ] . resident corneal cells and inflammatory cells invade...
to investigate the effects of loss of transient receptor potential vanilloid receptor 1 ( trpv1 ) on the development of neovascularization in corneal stroma in mice . blocking trpv1 receptor did not affect vegf - dependent neovascularization in cell culture . lacking trpv1 inhibited neovascularization in corneal st...
male and female lmna , lmna , and lmna mice were bred as described ( 12 , 15 ) . genotyping of mice was performed by pcr with genomic dna from tail biopsies ( 12 , 15 ) . mice were fed a chow diet and housed in a virus - free barrier facility with a 12 h light - dark cycle . an fti , abt-100 ( 18 ) , was administ...
hutchinson - gilford progeria syndrome ( hgps ) is caused by the accumulation of a farnesylated form of prelamin a ( progerin ) . previously , we showed that blocking protein farnesylation with a farnesyltransferase inhibitor ( fti ) ameliorates the disease phenotypes in mouse model of hgps ( lmnahg/+ ) . however ,...
the septic cavernous sinus thrombosis ( cst ) due to odontogenic infection is uncommon and leads to substantial morbidity and mortality . the peculiar anatomy of cervicofacial planes , dental structures , and its direct communication with cavernous sinus predisposes individual to development of septic cst in background...
septic cavernous sinus thrombosis ( cst ) related to dental infection is a rare clinical event . the septic cst is a disease of high morbidity and mortality . the prompt diagnosis and timely treatment of septic cst is cornerstone of successful outcome . the dental infection should be given due attention , as to p...
a 48-year - old man was incidentally detected as having a well - defined , heterogeneous enhancing soft tissue density lesion in the bilateral retroperitoneum . the lesions were found during ct while the patient was undergoing evaluation for a gallbladder polyp that was incidentally detected on ultrasonography . th...
adrenal myelolipoma is a rare , nonfunctional benign tumor that is composed of mature adipose tissue and hematopoietic elements . in the past , these tumors were accidentally discovered at autopsy . today , they are found much more frequently and incidentally , mainly because of the widespread use of noninvasive im...
frontal fibrosing alopecia ( ffa ) is a scarring alopecia characterized by progressive recession of the frontotemporal hairline . current treatment is aimed at stopping progression , and the combination of dutasteride and pimecrolimus is the most effective therapy . side effects associated with dutasteride are erec...
introductionfrontal fibrosing alopecia ( ffa ) is a scarring alopecia characterized by progressive recession of the frontotemporal hairline . current treatment is aimed at stopping progression , and the combination of dutasteride and pimecrolimus is the most effective therapy . side effects associated with dutaster...
limited rest time , high intensity , and competition rate of strenuous sports emphasize on the necessity of following the most suitable approach to manage the functional overload of professional athletes . a proper nutritional strategy is helpful in order to achieve proper recovery , with multiple competing periods a...
background : athletes recovery is important in improving their performance . nutritional strategies can be effective in enhancing recovery rate . choosing the best food items in appropriate intervals can play effective roles in resynthesis of fuels and recovery of muscle injury . beverage micro and macronutrient co...
von hippel - lindau disease ( vhl ; mim # 193300 ) is a hereditary multi - systemic tumour syndrome that pre - disposes affected individuals to haemangioblastomas of the central nervous system and retina , pheochromocytomas , clear - cell renal carcinomas , adenomas and carcinomas of the pancreas , paragangliomas , ren...
abstractvon hippel - lindau disease ( vhl ) is an autosomal dominant , familial neoplastic disorder with variable interfamilial and intrafamilial expression . vhl is characterized by pre - disposition to development of a combination of benign and malignant tumours affecting multiple organs . we provide molecular ev...
self - monitoring of blood glucose ( smbg ) provides real - time glucose readings for insulin and diet / exercise adjustments , and thus plays an important role in diabetes management for insulin - treated patients . its role in type 1 diabetes is well recognized and is recommended to practice at a certain frequency ...
background : the information - motivation - behavioral skills ( imb ) model of health behavior is an effective tool to evaluate the behavior of diabetes self - management . the purpose of this study was to explore behavioral factors affecting the practice of self - monitoring of blood glucose ( smbg ) within the frame ...
dogs are the source of several zoonotic diseases and their close contact with humans may increase the risk of zoonotic disease transmission particularly when dogs are free to roam . dogs in urban and rural areas can be used as sentinels in humans and wildlife to evaluate the diversity and environmental contamination ...
a cross - sectional study was made on 89 inhabitants and their dogs from a rural community of yucatan , mexico , to determine the serological prevalence of some zoonotic parasitic agents . samples were taken to monitor the presence and intensity of infection with gastrointestinal parasites in dogs . in humans , the s...
renal arteriovenous malformations ( avms ) are rare anomalous arterial and venous connections commonly presenting with spontaneous hematuria and recurrent flank pain . a liquid embolizer composed of ethylene - vinyl alcohol ( evoh ) dissolved in dimethyl sulfoxide ( dmso ) , mixing with tantalum powder for radio - op...
abstractonyx is an emerging treatment modality for visceral vascular malformations , especially in cases in which delicate nidal penetration of the arteriovenous malformation ( avm ) is desired . a computed tomography ( ct ) image presentation of hyperdense striations along the renal medulla secondary to the tantalum...
cobalamin , c63h88o14n14pco ( figure 1 ) , participates in only two known mammalian enzymatic reactions . yet , these two cbl - dependent enzymes , cytosolic methionine synthase ( ms ) [ ec 2.1.1.13 ] , requiring methylcobalamin ( mecbl ) , and mitochondrial methylmalonyl - coa mutase ( mu ) [ ec 5.4.99.2 ] , requiring...
background . nos/no inhibitors are potential therapeutics for sepsis , yet they increase clinical mortality . however , there has been no in vivo investigation of the ( in vitro ) no scavenger , cobalamin 's ( cbl ) endogenous effects on nos/no / inflammatory mediators during the immune response to sepsis . metho...
aortic valve stenosis is a quite frequent valvular disease which could require surgical treatment [ 1 , 2 ] . aortic valve replacement by open chest surgery is still considered the gold standard for symptomatic patients , but recently transcatheter aortic valve implantation ( tavi ) has become an option for patients ...
introductiontranscatheter aortic valve implantation is the option of choice for high surgical risk patients suffering from symptomatic aortic stenosis . we aimed to evaluate the influence of baseline global longitudinal strain on left ventricular mass regression after the procedure.methodswe enrolled 23 patients with...
rhinophyma , exuberant hypertrophic acne , with tumoral aspect of the skin of nasal pyramid is characterized by large , bulbous , erythematous appearance of the nose . there were incriminated several factors such as : the excess of steroid hormones ( androgens ) , the presence of a parasite ( demodex folicolorum)[1 ,...
the aim of the article is to present an update on the pathophysiology , clinical features and treatment of rhinophyma . a 56 years old patient , living in urban area , presented with a giant rhinophyma which caused him not only upper airways obstruction and difficulty in eating , but also aesthetic and psycho - social ...
hemangiopericytoma is a mesenchymal tumor that occurs most commonly in the soft tissues of the upper and lower extremities , pelvis , and retroperitoneal space and seldom in visceral organs ( 1 ) . due to its vascular origin transarterial embolization is a procedure which can be performed prior to surgery of highly v...
primary hemangiopericytoma of the rib is extremely rare and only a few cases have been reported . a 62-yr - old man presented with an aching chest pain and dyspnea . thoracic computed tomography revealed a homogenous mass expanding the right seventh rib . a diagnosis of hemangiopericytoma was established by percuta...
influenza is an acute respiratory disease caused by an rna virus belonging to the orthomyxoviridae family . influenza viruses are classified into three types ( a , b and c ) based on matrix protein ( m ) or nucleoprotein ( np ) and are further characterized by both hemagglutinin ( h ) and neuraminidase ( n ) proteins...
please cite this paper as : harmon et al . ( 2010 ) a matrix gene based multiplex realtime rtpcr for detection and differentiation of 2009 pandemic h1n1 and other influenza a viruses in north america . influenza and other respiratory viruses 4(6 ) , 405410 . background the emergence in humans of pandemic ( h1...
our work is funded by the medical research council , eu grant qlk6 - 2000 - 530 , and by the muscular dystrophy campaign .
gene - expression profiling has yielded important information about simple systems , but complex tissues have not yet been widely profiled . four recent studies of mammalian skeletal muscles have added to the catalogs of their gene expression differences , but have yet to lead to better understanding of the molecular...
postpneumonectomy syndrome ( pps ) is an ominous complication , with prevalence in children ranging from 1 in 6 to 1 in 5 pneumonectomies . it is caused by mediastinal shift following massive lung resection that results in compression and stretching of the great vessels and airways . it usually occurs after right...
highlightsafter esophageal atresia repair , if postpneumonectomy syndrome develops , an associated esophageal lung must be considered.contrast esophagography , with the patient lying on the side of collapsed lung , is the optimal diagnostic study.in infants with postpneumonectomy syndrome , infusion of normal saline in...
fifty to eighty - five percent of the population in a modern industrial society experience low back pain more than once in their lifetime . low back pain is one of the common symptoms having a prevalence rate of 40 - 67.6% and a point prevalence of 20% ( 1 - 4 ) . approximately 50% of patients who experience low ba...
many factors are associated with the development of low back pain . among them , exercise , obesity , smoking , age , educational level and stress are the most common . this study examined the association of these factors with low back pain . an additional aim was to determine a procedure for preventing low back pa...
cell - to - cell and interorgan exchange of nutrients and information is essential for growth , development , successful reproduction , and environmental adaptation of multicellular organisms . higher land plants have evolved a plant - specific symplastic network connected via plasmodesmata ( pd ) , cytoplasmic conne...
long - distance phloem transport of small metabolites has long been the subject of many different studies concentrating on resource allocation and signalling between plant organs . also , phloem movement of viruses has long been examined as the route for systemic infection of the plant . only recently , the transpo...
in 1980 the health care financing administration ( hcfa ) , in cooperation with the health policy center of brandeis university , began planning a demonstration program to provide and finance long - term care services . this demonstration program uses a social health maintenance organization ( s / hmo ) to combine ac...
in this article , case management departments and roles during the early years of the social health maintenance organization ( s / hmo ) demonstrations are compared . these organizations provide acute and chronic care services under a prepaid plan for the elderly . eligibility criteria for case management and chron...
the majority are benign ; however , inflammatory symptoms ( pain , reddened skin ) and facial asymmetry are characteristics that strongly suggest a malignant lesion . the duration of complaints in such a histologically diverse group of benign tumors and malignancies can vary greatly . facial nerve weakness alarms t...
the objectives of this article are to assess the frequency and significance of facial paralysis and undiagnosed nerve infiltration in patients with parotid malignancies . 103 patients with parotid gland malignancies were treated in a single institution , the tertiary center for ent at the university department in poz...
catatonia as a syndrome was described first in the year 1874 by the german psychiatrist karl karrl kahlbaum as cardinal features noticed are not communicating or repeating what others speak or gesturing what others gesture , extreme negativism or automatic obedience without interpretation of the command , which is su...
background : the term catatonia was first introduced in 1874 and several etiologies , both organic and psychiatric have been attributed to the clinical phenotype of catatonia . the interesting feature is their response to lorazepam irrespective of their etiology.patients and methods : four patients admitted with verb...
adrenal cyst thus a rare disease entity , lacks common clinical features , making it difficult to diagnose preoperatively , especially before the introduction of modern radiological devices , computerized tomograms and sonograms . although several hundred cases have been repoted in world literature , the majority of ...
adrenal lymphangiectatic cyst is a very rare pathological and clinical disease entity , and its clinical silence and lack of characteristic symptoms and signs makes it difficult to diagnose preoperatively . we experienced a case of adrenal lymphangiectatic cyst , accompanied by severe refractory hypertension , which ...
the renin - angiotensin system ( ras ) plays a key role in several target organs , such as heart , blood vessels , and lungs , exerting a powerful control in the maintenance of the homeostasis [ 14 ] . this system is activated by the conversion of the angiotensinogen to the inactive peptide angiotensin ( ang ) i thro...
angiotensin ( ang)-(17 ) is now recognized as a biologically active component of the renin - angiotensin system ( ras ) . the discovery of the angiotensin - converting enzyme homologue ace2 revealed important metabolic pathways involved in the ang-(17 ) synthesis . this enzyme can form ang-(17 ) from ang ii or less...
diosmin is a member of the citrus flavonoid family and is a modified form of hesperidin [ 1 - 4 ] . it is a semisynthetic drug that is used as an oral phlebotropic drug in the treatment of venous disease , i.e. , chronic venous insufficiency and hemorrhoidal disease . in some countries , daflon 500 mg ( which conta...
purposekidney stones ( nephrolithiasis ) are a widespread disease . thus , blocking stone formation and finding new therapeutic methods is an important area of study . diosmin ( a major component of the bile ) is known to have antioxidant as well as renoprotective effects . the present investigation aimed to eval...
invasive candidiasis ( ic ) is a serious infection associated with a high mortality rate and limited definitive diagnostic signs . colonization is a key component of ic pathogenesis , yet the significance of gastrointestinal candida colonization as a predictor of ic remains controversial . although yeast are normal b...
a matched case - control study was conducted to investigate gastrointestinal colonization with yeast as a predictor of invasive candidiasis ( ic ) in patients who underwent an enteric pathogen test . no significant association was detected between gastrointestinal colonization and ic . however , gastrointestinal co...
cellular and viral oncogenes , such as ras and adenovirus e1a , trigger p53 activation by inducing the expression of arf 9 , which inhibits mdm2 mediated p53 degradation . arf is lost in 58% of cancers9 , which had previously been invoked as the critical factor that prevents p53 activation in e1b-55k infected tumor c...
the transcription factor p53 guards against tumor and virus replication and is inactivated in almost all cancers . p53 activated transcription of target genes is thought to be synonymous with the stabilization of p53 in response to oncogenes and dna damage . during adenovirus replication , the degradation of p53 by...
hypokalemic periodic paralysis is a rare disorder characterized by transient attacks of flaccid paralysis of varying intensity and frequency . reported incidence of hypokalemic paralysis in patients with type 1 renal tubular acidosis ( rta ) type 1 rta or distal rta ( drta ) is a disorder of renal tubular acidificati...
we report recurrent hypokalemic periodic quadriparesis in a 30-year - old woman . patient had also symptoms of multiple large and small joint pain , recurrent oral ulceration , photosensitivity and hair loss that were persisting since last 6 months and investigations revealed systemic lupus erythematosus ( sle ) with...
to start the discussion , the relevant results from a survey of the isds community ( 3 ) were presented . there were 165 responders from 28 countries . when asked whether they collaborated regularly with workers from a sector different from theirs , 93% answered affirmatively . seventy - two percent of the responde...
motivated by the perception that human and veterinary medicines can cooperate in more ways than just fighting zoonoses , the authors organized a roundtable during the 2013 annual meeting of the international society for disease surveillance ( isds ) . collaborations between human and animal health sectors were report...
empathy is one of the most important aspects in the medical profession ( 110 ) and when it is employed in the right capacity it can be very effective in the relationship between doctor and patient ( 11 ) . empathy is a very important tool in understanding the concerns and suffering of the patient from their perspecti...
introductionempathy , an essential component of the physician patient relationship , may be linked to positive patient outcomes . this study aimed to determine the empathy score among student residence assistants ( ras).methodsin this descriptive design ( cross - sectional study ) , 102 iranian ras participated in t...
increased recognition and improved understanding of the neuropathic component of low back pain raises the potential for the development of mechanismbased therapies . open and retrospective studies suggest that agents like tapentadol and topical analgesics such as the capsaicin 8% patch and the lidocaine 5% medicated...
abstractbackground and objectivelow back pain ( lbp ) is one of the most common chronic pain conditions . this paper reviews the available literature on the role of neuropathic mechanisms in chronic lbp and discusses implications for its clinical management , with a particular focus on pharmacological treatments.data...
teaching methods with advanced technology have significantly increased in clinical nursing skills training over the past decade . today , due to constant technological changes in clinical environments , working with patients , especially in adverse conditions , has become more complicated for nurses . therefore , n...
background : new teaching methods are essential in the promotion of competence in nursing students . measuring blood pressure , which is one of the most essential skills , is the foundation of nursing care and clinical decision - making , and students should be trained to master this skill . this study aimed to deter...
conventional esophagogastroduodenoscopy ( egd ) is limited by the requirement for sedation and its associated recovery time , endoscopy suite resources , and anesthesia monitoring . these limitations likely decrease the effectiveness of current screening strategies for esophageal precancerous lesions 1 . unsedated sm...
background unsedated transnasal esophagoscopy ( tne ) may offer a less expensive , mobile alternative to sedated esophagogastroduodenoscopy ( egd ) for evaluations of reflux related complications . comparisons of imaging quality by these methods are lacking . methods two reviewers evaluated videos of tne and egd ...
the introduction and widespread use of antenatal ultrasonography has increased the diagnosis of fetal hydronephrosis in utero [ 1 - 3 ] . one of the most common causes of antenatally diagnosed hydronephrosis is ureteropelvic junction obstruction ( upjo ) . many reports deal with the unilateral idiopathic upjo with ...
purposethe management of prenatally detected bilateral ureteropelvic junction obstruction ( upjo ) remains controversial . we attempted to develop a treatment plan for patients with severe bilateral upjo.materials and methodswe evaluated the records of 13 patients with prenatally diagnosed grade 3 or more bilateral h...
insulin receptor is a tetramer protein composed by two extracellular subunits and two transmembrane subunits . the subunits have a binding site to insulin while the subunits contain an intrinsic tyrosine kinase activity towards intracellular side . insulin binding to the subunit leads to a conformational chang...
inflammation and insulin resistance are common in several chronic diseases , such as obesity , type 2 diabetes mellitus , metabolic syndrome , cancer , and cardiovascular diseases . various studies show a relationship between these two factors , although the mechanisms involved are not completely understood yet . her...
urinary incontinence ( ui ) after radical prostatectomy ( rp ) is not uncommon and one of a major postoperative complication , which has been reported in 2% to 87% of patients , depending on the definitions , types of surgery , and diagnostic methods . the cause of persistent postprostatectomy incontinence ( ppi ) is...
purposewe compared bladder and urethral functions following radical prostatectomy ( rp ) between men with and without urinary incontinence ( ui ) , using a large - scale database from snu - experts - of - urodynamics - leading ( seoul ) study group.materials and methodssince july 2004 , we have prospectively collected ...
autoantibodies are a hallmark in the diagnosis of many systemic autoimmune rheumatic diseases ( sard ) including idiopathic inflammatory myopathies ( iim ) ( reviewed in [ 1 , 2 ] ) . most of those autoantibodies are directed to intracellular proteins , including nuclear and cytoplasmic antigens , and based on their ...
diagnostic tests are needed to aid in the diagnosis of necrotizing myopathies associated with statin use . this study aimed to compare different technologies for the detection of anti - hmgcr antibodies and analyze the clinical phenotype and autoantibody profile of the patients . twenty samples from myositis patien...
the prevalence of prostate cancer in korea quadrupled between 2002 and 2008 , with the highest increased incidence rate in total forms of malignancy . the incidence of prostate cancer in korea increased up to 24.8 per 100,000 men in 2009 in comparison with 13 per 100,000 men in 2008 . certain environmental elements...
purposethe purpose of this article was to announce the establishment of the multicenter korean prostate cancer database ( k - cap ) and to provide urologists with details about k - cap 's methodology.materials and methodsthe initial participating k - cap institutions include five medical centers in korea . first , we...
posterior vitreous detachment ( pvd ) is defined as the separation of the posterior hyaloid from the internal limiting membrane . it is age - related and becomes noticeable after the sixth decade of life ( up to 63% prevalence ) and is related to synchysis senilis . vitreous separation can cause visual symptoms suc...
purpose . to determine the efficacy of 23-gauge pars plana vitrectomy ( ppv ) for symptomatic posterior vitreous detachment ( pvd ) on visual acuity ( va ) and quality after multifocal intraocular lenses ( iols ) . methods . in this prospective case series , patients who developed symptomatic pvd and were not satisfi...
as result of improved surgical techniques and newer immunosuppressive regimens contributing significantly to better graft survival , exocrine pancreas transplantation remains the standard treatment of choice for patients with diabetes mellitus complicated by end - stage renal disease . histological assessment continu...
a pancreas transplant is a surgical procedure to place a healthy pancreas from a donor into a patient whose pancreas no longer functions properly . exocrine pancreas transplantation remains the standard treatment of choice for patients with diabetes mellitus complicated by end - stage renal disease . the use of pan...
a 71-year - old man visited us with a chief complaint of a 1-year history of a mass in the right scrotum . the patient had a 15-year - history of stroke and hypertension , for which he was receiving medical treatment . the patient also had an 8-year - history of hypertensive end - stage renal disease , for which he...
various tumors can occur in the scrotum . of them , angiomyofibroblastoma - like tumors are very rare mesenchymal tumors . angiomyofibroblastoma - like tumors can not be easily differentially diagnosed from other malignant tumors invading the male genital tract on the basis of clinical characteristics and imaging s...
the hemoglobinopathies are the most common inherited single - gene disorders worldwide , resulting from the heterozygote advantage against malaria ( 1 ) . among the hemoglobin disorders , -thalassemias are found with high gene frequencies in african , asian and the mediterranean populations , whereas -thalassemias ar...
objective(s):iran is considered as one of the high - prevalence areas for -thalassemia with a rate of about 10% carrier frequency . molecular diagnosis of the disease is performed both by direct sequencing and indirectly by the use of polymorphic markers present in the beta globin gene cluster . however , to date the...
epidemiological data indicate that mortality is higher than 2530% in patients with sepsis and 4050% in patients with septic shock . delayed diagnosis and inadequate antimicrobial therapy choosing optimized antimicrobial therapy according to the causative pathogen of sepsis can drive significant improvements in the pr...
background : serum procalcitonin ( pct ) levels differ in patients with bacterial or fungal infections and are significantly elevated in patients with gram - negative bacteremia . we evaluated the diagnostic accuracy of different inflammatory markers to discriminate sepsis caused by different pathogens.materials and me...
the red reflex test is an effective screening test in the early diagnosis of various illnesses and disorders of eyes , such as cataracts , glaucoma , retinoblastoma , retinal disorders . the base of the red reflex test is that if the ophthalmoscope light directly placed on the optic axis of the dilated pupil , the...
objective : red reflex test is an effective screening tool in the early diagnosis of neonatal eye abnormalities . the aim of this study was to detect the sensitivity and specificity of red reflex assessment in neonates , performed by pediatricians ( or other care providers ) in comparison with ophthalmologists . also a...
approximately 150,000 species of flies are described in the world and more than 24,000 species are described in the neotropics . the genus zaprionus ( diptera , drosophilidae ) consists of approximately 60 species of which about 10 are grouped in the subgenus anaprionus and 50 in the subgenus zaprionus . phylogenet...
abstractthe genus zaprionus consists of approximately 60 species of drosophilids that are native to the afrotropical region . the phylogenetic position of zaprionus within the drosophilidae family is still unresolved . in the present study , ultrastructural features of spermatozoa of 6 species of zaprionus as well as...
allergy nurses work with various tests aimed at diagnosing allergic diseases and other hypersensitivity disorders . common tests are skin prick test ( spt ) , where different allergens are used , penicillin ( pc ) provocation tests , and tests with various respiratory irritants , such as methacholine ( mch ) . many...
background . allergy nurses are exposed to allergens and respiratory irritants , and there are no national guidelines addressing personnel safety when working with these agents . objective . to investigate the prevalence of allergies , asthma , and hypersensitivity symptoms among allergy nurses and the use of protect...
policy makers across the political spectrum , as well as many clinicians and physician professional associations , have proposed that better information on comparative clinical effectiveness should be a key element of any solution to the us health - care cost crisis . this superficial consensus hides intense disagree...
backgroundpolicy makers across the political spectrum , as well as many clinicians and physician professional associations , have proposed that better information on comparative clinical effectiveness should be a key element of any solution to the us health - care cost crisis . this superficial consensus hides intens...
yoga therapeutics is an increasingly appreciated discipline , particularly in india where it is overseen by the ministry of health and family welfare 's department of ayurveda , yoga and naturopathy , unani , siddha and homeopathy ( ayush ) . not many studies have assessed the influence of integral yoga practices on ...
objective : certain psychological and health variables are commonly measured in india . this study evaluates the effects of integral yoga practices on these variables and also the consistency of correlations observed between them.materials and methods : the study was a pre - post intervention study . the variables ...
ethics : the animal care and use committee of the national institute of animal health ( niah ) approved all animal procedures prior to initiation of this study ( authorization numbers : 12 - 027 , 12 - 056 , 12 - 081 , 13 - 024 , 13 - 054 and 14 - 009 ) . all experimental infections were performed in cubicles w...
an elisa kit for detection of antibodies to a nonstructural protein of foot - and - mouth disease ( fmdv ) was further evaluated using sequentially collected serum samples of experimentally infected animals , because the sensitivity of the kit used in a previous study was significantly low in field animals . th...
diffuse idiopathic skeletal hyperostosis ( dish ) is non - inflammatory systemic disease which leads to ossification of ligaments and entheses . especially ossification of longitudinal ligaments causes the ankylosing spine . according to utsinger , dish is diagnosed when radiographs present the ossification of at lea...
abstractdiffuse idiopathic skeletal hyperostosis ( dish ) is characterized by calcifications and ossification of ligaments and tendon insertions . the patients with dish are susceptible to spinal column injury with trivial trauma due to immobilization of vertebrae and this easily leads to spinal cord injury . howev...
renal cell carcinoma ( rcc ) accounts for approximately 2 to 3% of cancer in adults of the general population . compared with other types of cancer , rcc is difficult to diagnose and shows different clinical patterns . in particular , rcc is associated with such a low survival rate in kidney transplantation patient...
purposein a group of surgery patients diagnosed with renal cell cancer , those who underwent dialysis were compared with those who received a kidney transplant.materials and methodsthe 43 subjects included in this study were patients who had been undergoing dialysis because of end - stage renal disease or had undergone...
the subjects had been diagnosed as pd for the first time or diagnosed as pd by other clinicians but had never been treated before . the diagnosis of pd was established according to the criteria of the united kingdom parkinson s disease society brain bank.15 we excluded atypical or secondary parkinsonisms , and the di...
background and purposeorthostatic hypotension ( oh ) is known to be present even in patients with early parkinson s disease ( pd ) . to affirm the presence of oh and find correlation between oh and other dysautonomic symptoms in pd , this study has done in newly - diagnosed pd patients.methodsforty-five non - demented ...
nerve compression and traction may cause disorders of the intraneural microcirculation , lesions in the myelin sheath and the axon , as well as alterations in the supporting connective tissue . the entrapment of a peripheral nerve occurs as a result of its passage through an anatomical compartment that has become too...
carpal tunnel syndrome ( cts ) is the most common median nerve neuropathy , accounting for 90% of all neuropathies . carpal tunnel syndrome presents in 3.8% of the general population , with a higher prevalence among women . there are several risk factors associated with cts , including both medical and non medical ...
acquired factor viii deficiency is caused by the development of autoantibodies directed against circulating coagulation factor viii , which inhibits its function [ 1 , 2 ] . it may be associated with pregnancy , the postpartum period , autoimmune conditions , drugs , lymphoproliferative disorders , or malignancies . ...
acquired factor viii deficiency is very rare , often fatal . it is associated with pregnancy , autoimmune diseases , malignancy , and drugs , although no underlying cause is found in 50% . a 49-year - old male was referred with right shoulder bruising . the coagulation test showed a prolonged activated partial th...
however , acetylcholinesterase inhibitors have several disadvantages , such as development of residual blockade and hemodynamic adverse effects . sugammadex , a -cyclodextrin derivative , is a new reversing agent that has been in use recently . sugammadex is preferred because of its advantages during extubation and...
backroundsugammadex is a reversal agent with well known advantages but it s effects on haemostasis and bleeding have been a topic of interest . septoplasty is a common surgical procedure with postoperative respiratory complications and bleeding . the aim of this study is to investigate the effects of sugammadex on ...
depressive symptomatology has been recognized as a feature of schizophrenia since bleuler first introduced this term in 1908 . he described depressive symptoms as either directly triggered by the very process of the disorder in the acute stages ( i.e. as essential symptoms of schizophrenia ) or as secondary symptoms ...
depressive symptoms are common in schizophrenia and they can occur during any phase of the disorder . early diagnosis , adequate differential diagnosis and promptly initiated interventions have been shown to reduce further deterioration of illness and to improve patients quality of life . common psychiatric rating sc...
sample collection : 20 ml of fresh urine was collected from individual cattle in lopburi , chainat and nakhon nayok provinces in the central region of thailand from october 2012 to february 2014 for the propose of disease surveillance . after collection , the samples were kept in cool storage ( 4c ) and transport...
leptospirosis has been one of the worldwide zoonotic diseases caused by pathogenic leptospira spp . many molecular techniques have consecutively been developed to detect such pathogen including loop mediated isothermal amplification method ( lamp ) . the objectives of this study were to evaluate the diagnos...
mammals possess various muscle types that exhibit particular physiological properties to fulfill their diverse functions . for example , the heart muscle beats continuously throughout the life of the animal , slow skeletal muscle fibers support endurance exercises , and fast skeletal muscles empower peak forces but f...
in drosophila , fibrillar flight muscles ( ifms ) enable flight , while tubular muscles mediate other body movements . here , we use rna - sequencing and isoform - specific reporters to show that spalt major ( salm ) determines fibrillar muscle physiology by regulating transcription and alternative splicing of a larg...
rheumatoid arthritis ( ra ) is characterized by synovial inflammation and hyperplasia , autoantibodies production ( rheumatoid factor and anti - citrullinated protein antibodies [ acpa ] ) , and cartilage and bone destruction . numerous lines of evidence support the potential contribution of fibroblast - like synoviocy...
rheumatoid arthritis ( ra ) is characterized by synovial inflammation and hyperplasia . fibroblast - like synoviocytes ( flss ) are apoptosis - resistant and contribute to the pathogenesis of ra by producing cytokines and proteolytic enzymes , which degrade the extracellular matrix . we evaluated the proapoptotic a...
airway management in the obese patient can be challenging , as airway difficulties are often complicated by obesity . the morbidly obese patients may require several attempts at intubation and have a greater likelihood of use of accessory airway devices . application of positive end expiratory pressure ( peep ) at ...
background : the primary objective of this study was to compare the effect of ventilation using the proseal laryngeal mask airway ( plma ) with facemask and oropharyngeal airway ( fm ) , prior to laryngoscopy , on arterial oxygenation in morbidly obese patients undergoing bariatric surgery.methods:forty morbidly obese ...
fusion of haploid cells to form a diploid zygote is the defining event of sexual reproduction in eukaryotes ( lillie , 1913 ) . in organisms from every eukaryotic taxon , the plasma membranes of gametes of opposite sex or mating type come into intimate contact and then fuse to form the zygote ( bianchi et al . ver...
summarysexual reproduction is almost universal in eukaryotic life and involves the fusion of male and female haploid gametes into a diploid cell . the sperm - restricted single - pass transmembrane protein hap2-gcs1 has been postulated to function in membrane merger . its presence in the major eukaryotic taxa anim...
autoimmune pancreatitis is a fibro - inflammatory form of chronic pancreatitis that accounts for 5%-6% of chronic pancreatitis . type i involves both genders but is more prevalent among males and associated with hyperimmunoglobulin g4 , anti - nuclear antibody , anti - smooth muscle antibody , anti - lactoferrin anti...
autoimmune pancreatitis is a fibro - inflammatory form of chronic pancreatitis . it is diagnosed by the combination of imaging studies such as a ct scan and pancreatography , laboratory analyses that include igg4 and/or autoantibodies , histopathological evaluations and positive response to corticosteroid therapy . ...
cancer is one of the major causes of childhood death in the developed and developing countries . it accounts for 4% of death of children under 5 years of age and 13% of children 5 - 15 years of age in the iranian population ; contributing to 15% of total loss of life in the under 15- year age group . however , desp...
backgroundfindings demonstrated that parents of children with cancer experience elevated levels of distress , depression , anxiety , posttraumatic stress symptoms , and subjective symptoms of stress . in this study , we determined effectiveness of mindfulness - based cognitive therapy ( mbct ) on reduction of depressio...
chorea is the ceaseless occurrence of rapid , jerky , dyskinetic , involuntary flicking movement of hands , face , and other parts of body . huntington 's disease ( hd ) and drugs account for more than 50% of such patients . basic pathology involved in chorea and other hyperkinetic movements is damage to various pa...
a 3-year - old female patient developed chorea possibly due to an interaction between phenytoin , phenobarbital and clobazam used for generalized tonic clonic seizures . phenytoin withdrawal resulted in recovery within 24 hours . post reaction computerized tomography ( ct)-scan of brain was normal . combined use ...
cytosine methylation at cpg sites in the genomic dna is a well - characterized epigenetic modification involved in gene regulation and transposon silencing in mammals ( 1,2 ) . upon replication of methylated dna , cytosines in the newly synthesized strand are initially unmethylated ( resulting in a hemimethylated dup...
dna methylation is a well - characterized epigenetic modification involved in gene regulation and transposon silencing in mammals . it mainly occurs on cytosines at cpg sites but methylation at non - cpg sites is frequently observed in embryonic stem cells , induced pluriotent stem cells , oocytes and the brain . t...
anticipated pressures on fossil fuel resources in the coming decades mean that raw materials for the chemical industry must be found that can reduce our reliance on fossil - fuel - based feedstocks . hence , the development of new production processes for chemical syntheses from renewable resources is a challenge tha...
carbon dioxide utilisation ( cdu ) is currently gaining increased interest due to the abundance of co2 and its possible application as a c1 building block . we herein report the first example of atmospheric pressure carbon dioxide incorporation into oxetane to selectively form trimethylene carbonate ( tmc ) , which i...
cleft lip , cleft palate ( clp ) , or both are the most frequently occurring congenital facial deformities , with an incidence rate of 0.65% in newborns , influenced by ethnic and geographic variations.[1 - 2 ] the nasopharyngeal region is impacted by complex interactions of bony compartments , muscular functionality ,...
statement of the problem : individuals with cleft lip and cleft palate mostly have airway problems . introduction of cone beam computed tomography ( cbct ) and imaging software has provided the opportunity for a more precisely evaluating 3d volume of the airway . purpose : the purpose of this study was to analyze a...
the publication of the human genome sequence was a landmark in biological research ( lander et al . , 2001 ; venter et al . , 2001 ; www.ornl.gov/sci/techresources/human_genome/home.shtml ) . it provides the basis for understanding the role of all genes in normal physiology and disease pathology , particularly whe...
chemical probes for interrogating biological processes are of considerable current interest . cell permeable small molecule tools have a major role in facilitating the functional annotation of the human genome , understanding both physiological and pathological processes , and validating new molecular targets . to be...
decision - making strategies for optimal treatment of recurrent ovarian cancer ( roc ) are complex as new cytotoxic drugs and an increasing number of biological agents become available . this presents challenges in defining the optimal timing and sequencing of the drugs or treatment regimen . a controversial issue of...
most patients with recurrent ovarian cancer ( roc ) undergo a series of remissions and recurrences , therefore the additive or cumulative toxicity of chemotherapy must be factored into their treatment plan . there are challenges in defining tailored therapeutic approaches , including optimal timing and drug sequencin...
short anagen syndrome ( sas ) is a recently recognized congenital disease clinically characterized by persistently short fine hair since birth , due to a decreased duration of the anagen phase . the common complaint is that the hair does not grow long and that it has never been cut . only a few cases have been publ...
short anagen syndrome ( sas ) is a condition in which hair does not grow long . it usually perceived by parents in children around 2 - 4 years of age . it is a benign disease of the hair cycle . the condition is relevant from the standpoint of differential diagnosis with loose anagen syndrome . we report a case...
rheumatoid arthritis ( ra ) is one of the most prevailing inflammatory arthropathies that affects primarily able - to - work persons what attributes a high social significance to the disease . the development of ra is associated with the formation of a wide spectrum of autoantibodies , including rheumatoid factors ( ...
objective . to make individualised decisions regarding treatment is one of the most important challenges in clinical practise , and identification of sensitive and specific markers of prognosis is an important research question . the main objective of this study was to evaluate relationships between the level of auto...
pregestational type 1 diabetes mellitus is clearly associated with an increased incidence of adverse maternal , fetal , and neonatal outcome [ 14 ] , and several studies in the last two decades have shown that pregestational type 2 diabetes poses an emerging problem , with pregnancy outcomes at least as poor as in wome...
objective . to assess the incidence of adverse pregnancy outcome in native and nonnative dutch women with pregestational type 2 diabetes ( t2d ) in a multicenter study in the netherlands . methods . maternal characteristics and pregnancy outcome were retrospectively reviewed and the influence of ethnicity on outcom...
the vascular system is not only essential for the maintenance of tissue homeostasis , but also important for managing a wide variety of physiological processes . blood vessels are actively remodeled and reorganized depending on the tissue oxygen demand , suggesting that the maintenance of blood vessels is an active p...
as our understanding of molecular mechanisms leading to vascular formation increases , vessel maintenance including stabilization of new vessels and prevention of vessel regression began to be considered as an active process that requires specific cellular signaling . while signaling pathways such as vegf , fgf , and a...
black pakistani cobra ( naja naja karachiensis . ) is a highly venomous snake that is commonly found in southern parts of south asia . like other naja members , this cobra species found in southern pakistan produces potent venom , which is a major contributor in snake bite - related deaths in south asia . additiona...
using morphological analysis and biochemical testing , here for the first time , we determined the culturable gut bacterial flora ( aerobes and facultative anaerobes ) in the venomous black cobra ( naja naja karachiensis ) from south asia . the findings revealed that these snakes inhabit potentially pathogenic bacter...
cardiovascular diseases ( cvds ) are the prevalent cause of death in europe and the united states . this is despite general acceptance that a healthy lifestyle and risk factor management can prevent the development of cvd . furthermore , two - thirds of women who die suddenly from cvd have no previously recognize...
abdominal aortic calcifications ( aacs ) correlate strongly with coronary artery calcifications and can be predictors of cardiovascular mortality . we investigated whether size , shape , and distribution of aacs are related to mortality and how such prognostic markers perform compared to the state - of - the - art ac...
nineteenth and twentieth century biology was completely based on misleading ideological imposition that living entities are particular states of matter and in that era biologists have only made several attempts to deny the living organism of its veracity as an immortal soul , in favor of genes , molecules , atoms and s...
abstractthe author would like to thank professor gustavo caetano - anolls from department of crop sciences , university of illinois for his interest in his work . we may sometimes observe that there is a noticeable difference between the anecdote people narrate about the implications of a scientific paper and the rea...
numerous short and thick hairs set obliquely in the fibers of orbicularis oculi , corrugator and frontal part of occipito frontalis are inserted in the dermis of eye brows . the head of the eyebrows overlies the frontal sinus and the tail is usually in the region of zygomatiocofrontal suture . it is an appendage of...
eye brows are essential for esthetic and functional purposes . various kinds of eye brows are found in human species . protective function is one of the important functions of eye brows . double eye brow is a very rare condition found in human . this case report describes one of the rare cases of double eye bro...
involvement of the central nervous system ( cns ) in patients with carcinoma of the uterine cervix is rare and published studies state that only 1% of patients with cervical carcinoma develop cns metastases . most of the reports in the literature on cns metastases from cervical carcinoma are metastases to cerebral or...
abstractthis report describes the case of a 50-year - old woman with carcinomatous meningitis from squamous cell carcinoma of the uterine cervix . ultrasound showed an irregular hypoechoic mass in the cervix . contrast enhanced computed tomography imaging revealed intense linear enhancement along the falx cerebri s...
the great saphenous vein ( gsv ) is the most commonly used conduit for coronary artery bypass grafting ( cabg ) . the referenced standard method of harvesting the gsv is by way of the open surgical technique . depending on the required graft length , the average incision will vary between 20 and 40 centimetres . ...
conventional open harvest of the great saphenous vein ( gsv ) during cabg results in approximately 7% donor - site complications . using endoscopic vein harvesting ( evh ) the full gsv length can be harvested through a 3 cm incision . this nonsystematic review discusses several key issues concerning evh , based on...
gout is one of the oldest recognized afflictions in humans , with a documented history reaching back to the egyptians in 2640 bc . described by hippocrates as the arthritis of the rich due to its association with food and alcohol , gout is an inflammatory arthritis caused by precipitation of monosodium urate ( msu ) i...
gout is an inflammatory arthritis characterized by abrupt self - limiting attacks of inflammation caused by precipitation of monosodium urate crystals ( msu ) in the joint . recent studies suggest that orchestration of the msu - induced inflammatory response is dependent on the proinflammatory cytokine il-1 , underli...
the classic symptom of spinal canal stenosis is pseudoclaudication or neurogenic claudication.16 the classification of spinal stenosis proposed by arnoldi et al . ( 1976 ) remains useful.7 patients typically complain of pain , paresthesia , weakness , or heaviness in the buttocks radiating into lower extremities with w...
background : the long term outcomes of decompressive surgery on relief of pain and disability in degenerative lumbar canal stenosis are unclear . the aim of our study was to evaluate the outcome of surgical management of secondary degenerative lumbar canal stenosis and to analyze the effect on outcome variables using...
temporomandibular joint ankylosis is defined as the fusion of joint surfaces by bone or fibrous tissue . inability to open the mouth in temporomandibular joint ankylosis results in inability to maintain oral hygiene , inability to chew properly and esthetic problems.[13 ] this leads to dental caries , malocclusion , ...
aimthe purpose of this study was to evaluate the postoperative pain control and mouth opening in patients undergoing temporomandibular joint interpositional gap arthroplasty by either placing an epidural catheter in the incision wound and infusing ropivacaine 0.25% or by using a transdermal fentanyl patch.materials and...
metabolic and functional changes that derive from the natural aging process increase the number of diseases , fractures , and falls experienced by individuals , thereby causing patients to experience brief periods of inactivity , which culminate in joint immobilization and may directly influence the development o...
[ purpose ] to evaluate the efficacy of pre - exercise on immobilization and subsequent recovery of white gastrocnemius ( wg ) and soleus ( sol ) muscles of female rats . [ subjects and methods ] thirty , 8-month - old , female wistar rats were randomly and evenly allocated to six groups : sedentary ( s ) ; imm...
pompe disease is characterized by a deficiency of the glycogen - degrading lysosomal enzyme , acid alpha - glucosidase ( gaa ) , . in classic infantile - onset pompe disease ( iopd ) , glycogen deposition in cardiac , skeletal , and respiratory muscles causes severe cardiomyopathy , hypotonia , and respiratory failur...
correlations between angiotensin - converting enzyme ( ace ) genotype ( i / i , i / d , d / d ) , disease severity at baseline and response to enzyme replacement therapy ( ert ) were assessed in the pompe disease late - onset treatment study ( lots ) . no correlations were observed between ace genotype and disease se...
the amas was administered to 298 undergraduate students ( 133 males and 165 females ) of tabriz university in iran who majored in different disciplines of human sciences ; they were enrolled in entry - level mathematics courses and voluntarily participated in the study . college research examination board approved th...
objectivethe aim of this study is to explore the confirmatory factor analysis results of the persian adaptation of abbreviated math anxiety scale ( amas ) , proposed by hopko , mahadevan , bare & hunt.methodthe validity and reliability assessments of the scale were performed on 298 college students chosen randomly from...
respiratory syncytial virus ( rsv ) is one of the most prevalent causes of lower respiratory tract infection ( lrti ) related hospitalizations among infants younger than 2 years of age . almost all children are infected by rsv at least once before the age of 2 years , with a recurrent infection occurring in more than...
objectiveto determine the risk factors associated with lower respiratory tract infections ( lrti ) related hospitalizations in preterm infants receiving palivizumab throughout the high season for respiratory syncytial virus ( rsv ) infection.methodspremature infants who were commenced on palivizumab prophylaxis during ...
clinical trials of disease - modifying treatments for ad have been struck by adverse events involving the immune system . in the clinical trial of the active antiamyloid (a ) vaccine an1792 , a small but notable number of patients developed meningoencephalitis , and treatment with the passive anti - a immunotherapy a...
due to side effects in the form of meningoencephalitis in the interrupted phase ii an1792 trial of active antiamyloid (a ) immunization against alzheimer 's disease ( ad ) , there has been concern that anti - a immunization may cause destructive neuroinflammation . here , we report on two patients fulfilling clinical a...
the bioflavonoids hesperetin and naringenin are widely distributed in citrus fruits and juices as their glycosides , hesperidin and naringin , respectively . they are present in citrus aurantium as well as a wide variety of other citrus species 1 . the sugar moieties for both flavonoids consist of rhamnose plus glu...
bitter orange ( citrus aurantium ) extract is widely used in dietary supplements for weight management and sports performance . its primary protoalkaloid is p - synephrine . most studies involving bitter orange extract and p - synephrine have used products with multiple ingredients . the current study assessed th...
there is emerging evidence that time to biochemical failure is a robust prognostic factor for prostate cancer mortality and overall mortality in men receiving definitive radiotherapy [ 13 ] . interval to biochemical failure is also highly prognostic for prostate cancer mortality in men undergoing prostatectomy . on...
purposeto explore patterns of time to failure in men receiving high doses of permanent seed brachytherapy with or without external beam radiation therapy as a function of risk status.material and methodstwo thousand two hundred and thirty four patients were treated with prostate brachytherapy with median follow up of 8...
traditional systems of medicines have been in use for promotive , preventive , and curative health services since centuries in many parts of the world . being the oldest traditional system of medicine in india , ayurveda caters to about 80% of the population in developing countries as per the estimate of world health...
ash of silver is used in traditional systems of medicine for various neurological conditions like insomnias , neuralgias , anxiety disorders , and convulsions . the present study was conducted to evaluate the sedative - hypnotic activity of ash of silver in comparison to pentobarbitone ( standard drug ) in albino mic...