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27% of pregnant women are affected from preeclampsia ( pe ) which occurred in the second half of pregnancy and is defined mainly by the symptoms hypertension and proteinuria . 58% of these women develop hellp syndrome ( hemolysis , elevated liver enzymes , and low platelet count ) . preeclampsia is one of the lea...
preeclampsia is one of the leading causes of maternal and fetal morbidity and mortality . new molecular insights offer new possibilities of early diagnosis of elevated maternal risk . maternal risk factors , biophysical parameters like doppler examination of the uterine arteries and biochemical parameters allow ear...
after its composition was firstly described by billroth1 in 1856 , tcherkoff and sedlis2 reported lesions of the same type in the uterine cervix . later baggish and woodruff3 recognized it as a distinct type of cervical neoplasm from adenoid cystic carcinoma . the incidence of adenocarcinoma of the uterine cervix i...
adenoid basal carcinoma of the uterine cervix is uncommon neoplasia mostly occurring in postmenopausal women . it has excellent prognosis and a favorable clinical course . in addition , adenoid basal carcinoma is differentiated from adenoid cystic carcinoma by histologic and cellular morphologies , and immunohistoc...
nicotine is a chemical that is present in the mount of about 1% of the weight of cigarette tobacco . nicotine is the main active ingredient of tobacco and is also the main factor that leads to smoking addiction or dependence producing . cotinine , a major degradation product of nicotine metabolism , has been an imp...
a simple and sensitive high performance liquid chromatography - tandem mass spectrometry ( hplc - esi - ms - ms ) method was developed and validated for the quantification of creatinine in human urine . the analysis was carried out on an agilent zorbax eclipse xdb - c18 column ( 2.1 150 mm , 3.5 m ) . the mobile...
animals : adult male wistar - imamichi strain rats ( body weight ( bw ) , 220250 g ) were obtained from the imamichi institute for animal reproduction ( tsuchiura , japan ) . the animals were housed at constant ambient temperature of 24c with controlled lighting ( lights on , 05001900 hr ) and given free access to fo...
abstractwe have previously suggested that activation of the hypothalamic - pituitary - adrenal ( hpa ) axis is dependent on cyclooxygenase ( cox)-2-related signaling under infectious and restraint stresses , but less dependent on it under hypoglycemic stress . in the present study , we evaluated the neuronal activity...
this study included 25 patients of both sexes with mandibular fractures in the age group of 18 - 48 years , presenting no medical contra indications for the planned procedure . data collected from the patients included pre and postoperative panoramic radiographs , age at the time of injury , sex , and site of madibul...
introduction : the purpose of this study was to evaluate teeth involved in the line of fracture , clinically and radiographically , and their associated complications so as to indicate if they should be managed conservatively or extracted.materials and methods : data were collected from patients records treated of mand...
there is strong epidemiological and genetic evidence that genetic factors play a major , though variable role , in its pathogenesis . migraine patients are characterized between attacks on various cns - evoked responses by a deficit of habituation [ 1 , 2 ] , which may have a familial character [ 35 ] . by contrast...
in previous studies , we described subclinical abnormalities of neuromuscular transmission and cerebellar functions in migraineurs . the aim of this study was to search if these two functions are correlated in the same patient . thirteen migraineurs [ five without aura ( mo ) and eight with aura ( ma ) ] underwent ...
bladder cancer is the second most common genitourinary malignancy and the sixth most common cancer in the world . in china , the incidence of bladder cancer also increases with age , and the peak is reached approximately at the age of 60 years ; bladder cancer is three times more common in men than in women . among t...
backgrounds . tsp-1 is a glycoprotein that functions in the biology of bladder cancer . we investigated the relationship between the distribution of tsp-1 - 1223 a / g polymorphism ( rs2169830 ) and the clinical characteristics of bladder cancer . materials and methods . taqman assay was performed to determine th...
a 38-year - old male patient with a 40-pack - year history of smoking initially presented with sudden - onset right - sided facial nerve palsy which was diagnosed as idiopathic bell 's palsy and was treated with prednisolone . three weeks later , the patient developed a new left - sided facial palsy in addition to hi...
leptomeningeal carcinomatosis is rare , and its precise incidence is unknown . it is associated with a wide spectrum of solid and hematological malignancies . to complicate its diagnosis , the clinical presentation of leptomeningeal carcinomatosis can be variable . we report a case of a 38-year - old male with bilate...
since the advent of the hiv - aids pandemic across the globe , pneumocystis jiroveci pneumonia has been one of the most common defining illnesses of this condition . idiopathic cd4 lymphocytopenia is one such condition where the patient presents with such aids defining illnesses but with negative serological marker f...
idiopathic cd4 + lymphocytopenia ( icl ) is a rare disorder characterized by the presence of depleted cd4 cell line without the presence of hiv infection . slight male preponderance is noticed and is usually seen in the middle age group . opportunistic infections are the reason for their discovery and here we descr...
diabetes is a metabolic disease with the main symptom of chronic hyperglycemia caused by insufficient insulin action . most symptoms can not be noticed when the degree of the metabolic disorders caused by insufficient insulin action is mild . however , thirst , polydipsia , polyuria , and weight loss are observed i...
abstractin the evidencebased practice guideline for the treatment for diabetes in japan 2013 , a new concept of the glycemic control in patients with diabetes in japan has been declared from the japan diabetes society . the main objective value of hba1c was set to < 7% from the perspective of preventing microvascula...
urethritis in males that is caused by sexual transmission is a major health - care concern worldwide . gonococcal urethritis ( gu ) is a common sexually transmitted disease ( std ) that is caused by neisseria gonorrhoeae . common signs and symptoms in males are purulent discharge from the urethra with dysuria , per...
background : poor follow - up compliance of patients with infectious urethritis is a recognized and serious public health problem in thailand.aim:the aim of this study was to determine treatment outcomes and loss to follow - up rate of male patients with gonococcal urethritis ( gu ) and non - gu ( ngu ) at a sexually t...
for decades , tracking studies with eels have been conducted to reveal the oceanic migration routes to their mysterious spawning areas6,000 km from the european coast by using acoustic and archival tags ( tesch 2003 ) . recently , the use of pop - up satellite tags ( psats ) , developed for tracking large animals (...
the journey of the european eel to the spawning area in the sargasso sea is still a mystery . several trials have been carried out to follow migrating eels with pop - up satellite tags ( psats ) , without much success . as eels are very efficient swimmers , tags likely interfere with their high swimming efficiency ...
over the past years in italy , the current affairs press has produced ample information on the subject of haccp ( hazard analysis and critical control points ) with the goal of providing support to those in charge of food companies and to allow these companies to conform to that provided for by italian legislative decr...
with respect to food safety , many works have studied the effectiveness of self - monitoring plans of food companies , designed using the hazard analysis and critical control point ( haccp ) method . on the other hand , in - depth research has not been made concerning the adherence of the plans to haccp standards . d...
estrogen - based therapies decrease hot flashes by up to 90% , but their use is generally discouraged in breast cancer survivors and in women with an increased risk of breast cancer.13 several hormonal and nonhormonal therapies are claimed to alleviate hot flashes . these include hormonal agents , such as progestatio...
aimsin breast cancer survivors , we aimed to describe the frequency of hot flashes and night sweats , frequency and type of treatment , and the association of hot flashes and use of calcium supplements.methodscharts of breast cancer survivors were reviewed for information about hot flashes , treatment for hot flashes ,...
antidepressant medication is a standard treatment and the first choice for depressed patients in current psychiatric guidelines.1 approximately 60% of patients respond well to active treatment,24 but ~40%50% of patients using the full dosage and duration of antidepressant medications still have residual symptoms and ca...
objectiveoverlap of obstructive sleep apnea ( osa ) complicates diagnosis of depressive disorder and renders antidepressant treatment challenging . previous studies have reported that the incidence of osa is higher in patients with depression than in the general population . the purpose of this article was to inves...
adverse drug reactions ( adrs ) occur frequently with cardiovascular drugs leading to change in therapy , compliance , and increasing morbidity and mortality and inflating the healthcare cost . angiotensin - converting enzyme ( ace ) inhibitors have been increasingly used for the therapeutic management of several con...
background : adverse drug reactions ( adrs ) occur frequently with cardiovascular drugs leading to change in therapy , increasing morbidity , and mortality.aim:the study was conducted to evaluate the incidence of adrs due to angiotensin - converting enzyme inhibitors in cardiology department.materials and methods : a c...
melioidosis , a febrile illness with disease states ranging from acute pneumonia or septicemia to chronic or localized abscess formation , was first documented by whitmore and krishnaswami ( 1912 ) . the causative agent , burkholderia pseudomallei , was subsequently identified as a motile , gram - negative bacillus ,...
burkholderia pseudomallei and burkholderia mallei are closely related gram - negative bacteria responsible for the infectious diseases melioidosis and glanders , respectively . autotransporters ( ats ) comprise a large and diverse family of secreted and outer membrane proteins that includes virulence - associated inv...
repetitive lifting and unloading as well as moving with excessive weights have been known to be major causes of various musculoskeletal disorders and low back pain1 . such carrying or actions may increase the load on the spine while decreasing the pressure that protects the spine , thereby increasing the risk of ...
[ purpose ] the aim of this study was to determine the effect of low - frequency electrical stimulation on fatigue recovery of the erector spinae with cumulative fatigue induced by repeated lifting and lowering work . [ subjects ] thirty - two healthy men volunteered to participate in this study and they were ran...
cemento - ossifying fibroma ( cof ) is considered a benign osseous tumor , very closely related to other lesions such as fibrous dysplasia , cementifying periapical dysplasia , or cemento - osseous florid dysplasia , however , creating its own entity in the 1992 who classification . consequently , one of its principa...
cemento - ossifying fibroma ( cof ) is considered a benign osseous tumor . herewith , we present a case of multiple central ossifying fibroma in a 35-yeaold woman . intraorally , there was swelling in the left upper posterior teeth region and another diffused swelling in the fourth quadrant . radiographs revealed...
radiography is generally used in determining dental maturation and two - dimensional panoramic radiographs are mainly used in radiography as seen in the dental and forensic literature . however , different dental age estimation methods have been used to measure tooth development , which include diagrams , charts , an...
objectives : the aim was to investigate mandibular third molar ( 3 m ) 's maturation in the crossbite and normal sides by two- and three - dimensional analyses using cone beam computed tomography ( cbct).materials and methods : a retrospective study was performed using cbct of 25 patients ( 16 females and 9 males ; mea...
anemia represents a frequent complication in cancer patients as well as in chronic inflammatory diseases . it is an important cause of cancer - related fatigue , which considerably affects quality of life . anemia is in fact considered as a bad prognostic factor for survival regardless of tumor type . up to 40% of ...
anemia of cancer and chronic inflammatory diseases is a frequent complication affecting quality of life . for cancer patients it represents a particularly bad prognostic . low level of erythropoietin is considered as one of the causes of anemia in these pathologies . the deficiency in erythropoietin production resu...
acidithiobacillus ferrooxidans ( a. ferrooxidans ) is a gram - negative , extremely acidophilic , mesophilic , chemolithotrophic bacterium and the most well - studied acidophilic organism which is usually found in acid environments such as acid mine drainage , . due to its bioleaching capabilities , it is an impor...
acidithiobacillus ferrooxidans type strain dlc-5 , isolated from wudalianchi in heihe of heilongjiang province , china . here , we present the draft genome of strain dlc-5 which contains 4,232,149 bp in 2745 contigs with 57.628% gc content and includes 32,719 protein - coding genes and 64 trna - encoding genes . the...
protooncogenes expressed in murine embryonal carcinoma ( ec ) cells or their differentiated daughter cells include more or less ubiquitously expressed protooncogenes such as c - myc , c - k - ras , and c - abl , as well as c - onc genes with a very restricted expression pattern . examples of the latter are n - myc , ...
hiv / aids is increasingly affecting the health and welfare of children and undermining hard - won gains of child survival in highly affected countries . recent estimates from the joint united nations programs on hiv / aids ( unaids ) suggest that globally about 2.5 million children younger than 15 years of age are i...
introduction . clinical reports have indicated positive outcomes associated with disclosure of hiv - positive status in children . this study assessed the level and associated factors of hiv - positive status disclosure to hiv - infected children in northwest ethiopia . methods . institution - based cross - sec...
decreasing healthcare costs while maintaining optimal patient outcomes has been a recent focus of many institutions given changes in united states healthcare . cost reduction with optimal outcomes has been shown by switching from intravenous ( iv ) to oral ( po ) antibiotics for the treatment of pneumonia in the non ...
background : controlling healthcare costs without compromising patient care is a focus given recent healthcare changes in the united states . the purpose of this study was to assess clinical improvement in surgical intensive care unit ( sicu ) patients initiated on or transitioned to enteral antibiotics compared to t...
ganciclovir , a drug against cytomegalovirus ( cmv ) infection , is generally well tolerated , but can cause neurotoxicity such as encephalopathy . although ganciclovir - induced encephalopathy has been described in several reports , a literature search revealed that ganciclovir concentrations in the blood or cerebro...
backgroundganciclovir , a drug against cytomegalovirus ( cmv ) infection , is generally well tolerated , but can cause neurotoxicity such as encephalopathy . although ganciclovir - induced encephalopathy has been described in several reports , a literature search revealed that ganciclovir concentrations in the blood ...
plasma proteins are the primary targets of glycation following elevated levels of glucose in diabetes . amongst plasma proteins , albumin is one of the heavily glycated proteins because of its abundance , comparatively longer half - life and a higher number of free lysine and arginine residues . glycation accelerat...
background : protein glycation plays a significant role in diabetic complications . glycated hemoglobin ( hba1c ) is a known predictor of diabetes and its complications . albumin , found to be profoundly glycated in diabetes , and its level could regulate plasma protein as well as hemoglobin glycation.aim:we aimed to...
rup has long championed public access to research articles via a six - month embargo , and we thus support this aspect of the wellcome trust policy and the new rcuk policy . however , we question the value of a provision in their policies that specifies licensing terms for reuse of content by third parties . both o...
the existing public access policy for our three journals the journal of cell biology , the journal of experimental medicine , and the journal of general physiology is fully compliant with new policies from the research councils uk ( rcuk ) and the wellcome trust . in addition to mandating public access , the new po...
the relation between spatial and numerical cognition was first assumed by galton ( 1880 ) at the end of the nineteenth century . taking into account introspective reports he proposed that magnitude information might be analogically arranged through the location of numbers along a spatial axis oriented from left to ri...
a structural representation of the hand embedding information about the identity and relative position of fingers is necessary to counting routines . it may also support associations between numbers and allocentric spatial codes that predictably interact with other known numerical spatial representations , such as th...
ticks are blood - sucking ectoparasites which transmit serious diseases to animals and humans . they are considered as main vectors for transmission of many viral , bacterial , rickettsial and parasitical pathogens ( garcia 2007 ) . several tick species are important in veterinary medicine as vectors of theileriosis ...
background : ticks are important vectors of human and animal pathogens . they are considered as main vectors for transmission of many viral , bacterial , rickettsial and parasitical pathogens . the aim of the present study was to find out species diversity of ticks , which infested the domestic ruminants in zabol c...
modest cognitive dysfunction is consistently reported in children and young adults with type 1 diabetes ( t1d ) ( 1 ) . mental efficiency , psychomotor speed , executive functioning , and intelligence quotient appear to be most affected ( 2 ) ; studies report effect sizes between 0.2 and 0.5 ( small to modest ) in ch...
objectivethe aim of this study was to investigate the presence and correlates of clinically relevant cognitive impairment in middle - aged adults with childhood - onset type 1 diabetes ( t1d).research design and methodsduring 20102013 , 97 adults diagnosed with t1d and aged < 18 years ( age and duration 49 7 and 41 6...
a 57-year - old woman developed multiple ( > 20 ) melanoma in - transit metastatic nodules on her right thigh ( figure 1a ) , as confirmed by histological examination , after removal , six months earlier , of a primary 2.2 mm thick ulcerated nodular melanoma on her right leg for which the initial sentinel lymph node bi...
complete response can be difficult to assess after isolated limb perfusion ( ilp ) for metastatic in - transit melanoma , especially when numerous and unresectable post - necrotic persisting pigmented lesions occur . these residual lesions are mainly seen in the more superficial and pigmented types of metastatic dise...
prior to np[xl184 ] synthesis , the biodegradable copolymer plga 50:50 ( 17 kda ; 0.18 dlg ; lake shore biomaterials ) was modified to incorporate a peg moiety ( cooh - peg - nh2 ; 3.5 kda ; jenkem technology ) , which enhances both nanoparticle stability and circulation time . nanoparticles were synthesized with var...
nanoscale drug delivery vehicles can facilitate multimodal therapies of cancer by promoting tumour - selective drug release . however , few are effective because cancer cells develop ways to resist and evade treatment . here , we introduce a photoactivatable multi - inhibitor nanoliposome ( pmil ) that imparts ligh...
a 66-year - old woman with sjgren syndrome presented with a 5-year history of bilateral shoulder pain that was significantly worse on the right than the left side . the pain was reported to be constant in nature but worse at night , and completely prohibited activities above shoulder height . examination of the ...
we report the case of a patient with end - stage osteoarthritis who received a successful copeland resurfacing hemiarthroplasty through a mackenzie anterosuperior approach , which involves taking the anterior portion of the deltoid attachment from the acromion along with an osteo - periosteal sleeve . the patient wen...
hemophilia is a coagulation disorder characterized by acute hemorrhages into the musculoskeletal system leading eventually to arthropathy and disability . deficiency of factor viii ( hemophilia a ) accounts for 85% of cases and 15% are due to factor ix deficiency ( hemophilia b ) . acute bleeding increases the pres...
objective . to find out the presence of osteoporosis in hemophilic arthropathy patients and its correlation with clinical severity and serum levels of magnesium , copper , and zinc . methods . joint score , functional assessment score , bone densitometry , and serum magnesium , copper and zinc were done in twenty m...
irritable bowel syndrome ( ibs ) is a heterogeneous , idiopathic , gastrointestinal syndrome characterized by abdominal pain or discomfort , diarrhea , and/or constipation . a questionnaire survey conducted in students from a chinese university found that only 5.7% of respondents could be diagnosed with ibs , but epi...
backgroundseveral polymorphisms have been reported to be associated with irritable bowel syndrome ( ibs ) , including c825 t , the single nucleotide polymorphism ( snp ) , responsible for a truncated g protein 3 subunit ( gn3 ) , and the vall158met substitution in catechol - o - methyltransferase ( comt ) . we invest...
progression of chronic obstructive pulmonary disease ( copd ) assessed by decline in forced expiratory volume in one second ( fev1 ) is closely related to active tobacco smoking . it has been shown that smoking cessation decelerates the fev1 decline in patients with mild - to - moderate copd.1,2 it is also widely ass...
backgroundin addition to smoking , acute exacerbations are considered to be a contributing factor to progression of chronic obstructive pulmonary disease ( copd ) . however , these findings come from studies including active smokers , while results in ex - smokers are scarce and contradictory . the purpose of this st...
their general metabolic pathway in mammals involves cytochrome p-450 ( cyp ) enzyme - mediated oxidation to form hydroxylated metabolites and epoxides and further conjugation with glucuronide or glutathione to create corresponding conjugates , leading further to methylsulfonyl metabolites catalyzed by glutathione s - t...
polychlorinated biphenyls ( pcbs ) are widely distributed persistent organic pollutants . in vitro research has shown that plant cell cultures might transform lower chlorinated congeners to hydroxylated pcbs , but there are few studies on in vivo metabolism of pcbs by intact whole plants . in this research , poplar p...
the most frequently used neck disability questionnaires are the neck pain and disability scale ( npad ) and neck disability index ( ndi ) , which are validated in several languages [ 4 , 16 , 21 , 22 , 38 ] . to evaluate the effect of treatment programs for neck disorders it is necessary that questionnaires are res...
purposeto investigate relevant change on the neck pain and disability scale ( npad ) and neck disability index ( ndi ) and which questionnaire is the most responsive in patients with non - specific chronic neck pain ( cnp).methodsseventy - six patients with non - specific cnp in an outpatient tertiary rehabilitation se...
peritonitis is the most troublesome complication in patients on continuous ambulatory peritoneal dialysis ( capd ) . gram - positive organisms , especially staphylococcus aureus and staphylococcus epidermidis , are the most frequent causative pathogens the prevalence of vancomycin resistant enterococci ( vre ) in h...
peritonitis in a continuous ambulatory peritoneal dialysis patient by two different species of enterococci is a rare condition . we report a case of peritonitis from which vancomycin sensitive enterococcus faecalis and vancomycin resistant enterococcusc faecium were isolated . it also emphasizes the effectiveness o...
obesity results from the accumulation of excess adipose tissue ; however , it is not a single disorder but a heterogeneous group of conditions with multiple causes . major causes of the increasing prevalence of obesity include behavioral and environmental factors , such as excessive consumption of energy - dense food...
the gut microbiota refers to the trillions of microorganisms residing in the intestine and is integral in multiple physiological processes of the host . recent research has shown that gut bacteria play a role in metabolic disorders such as obesity , diabetes , and cardiovascular diseases . the mechanisms by which t...
curing type acetoxycolor tranlucentdensity approximately 1.04 g / ccskin formation time approximately 5 min at 30ccuring time approximately 24 h. for 2 mm thickness at 30cmovement accommodation approximately 0.61 n / mmelasticity approximately 260% curing type acetoxy density approximately 1.04 g / cc skin...
this article describes an industrial elastic silicone as a material for the laboratory fabrication of ear prosthesis . it has been tested for toxicity in lab animals by the sgs india pvt . ltd and approved as a material to pass the parameter of abnormal toxicity . this material therefore can be safely recommended...
during 20082013 , a total of 68 satellite or global positioning system radio collars were deployed on african buffalo captured in southern gonarezhou np ; in northern kruger np , south of the limpopo river ; and in zimbabwe , north of limpopo river ( on sengwe communal land ) . of the 68 buffalo , 47 were adult femal...
we report on the long - distance movements of subadult female buffalo within a transfrontier conservation area in africa . our observations confirm that bovine tuberculosis and other diseases can spread between buffalo populations across national parks , community land , and countries , thus posing a risk to animal a...
while nigeria has only two percent of the global population , it contributes 10% to the global maternal mortality burden . the average national maternal mortality rate is 545 per 100,000 while in the north eastern zone , it is 1,549 per 100,000 . annually , an estimated 52,900 nigeria women die ( about 1,000 per we...
background : maternal mortality remains a leading cause of death among women of reproductive age . while nigeria has only two percent of the global population , it contributes 10% to the global maternal mortality burden . antenatal care ( anc ) reduces the incidence of maternal mortality . however , financial capab...
early in life , parental interactions can serve as a buffer against the negative consequences of stress on physiology and learning ( stanton and levine , 1990 , kirschbaum et al . , 2003 , shionoya et al . , 2007 , taylor et al . , 2008 , however , if rearing conditions are suboptimal , parental stress or disrup...
disruptions in early life care , including neglect , extreme poverty , and trauma , influence neural development and increase the risk for and severity of pathology . significant sex disparities have been identified for affective pathology , with females having an increased risk of developing anxiety and depressive d...
primary cardiac tumors are quite rare , especially in the pediatric age group,13 and their atypical presentations often prevent a timely diagnosis.4 most primary cardiac tumors in the pediatric age group are benign ; autopsy studies in children have reported incidence rates ranging from 0.027% to 0.08%.4 one echocardio...
primary cardiac tumors are quite rare , especially in the pediatric age group , and their atypical presentations often prevent a timely diagnosis . most primary cardiac tumors in the pediatric age group are benign . fibromas are generally reported as the second most common primary cardiac tumors in the pediatric ag...
breast cancer is the most common cancer among women globally and one of the main concerns of societies , especially for women . according to the american cancer society report , breast cancer is diagnosed in about 1.3 million women annually worldwide and around 465,000 will die from the disease . present data is sh...
there is some evidence to suggest that a benefit might be derived from a program that incorporated both annual physical examination of the breast ( bpx ) and the teaching of breast self - examination ( bse ) . current investigation presents the profile of a multicenter community based intervention for evaluating the ...
overweight or obesity among american children has reached epidemic proportions . over the past 25 years , childhood overweight or obesity has nearly quadrupled in the united states , affecting almost 17% of children and adolescents aged 219 in 2007 - 2008 [ 2 , 3 ] . childhood overweight or obesity is defined as ha...
increasing epidemic proportions of overweight children in the united states presents formidable challenges for education and healthcare . given the popularity and pervasiveness of video gaming culture in north american children , the perfect opportunity arises to investigate the potential of video games to promote he...
since first described by quain in 1847 ( 1 ) , hundreds of abdominal aortic stenosis have been reported with many variations in anatomy . though , the complete absence of infrarenal aorta , seen in presenting case , is extremely rare . this represents the first case of complete segmental occlusion of infrarenal aor...
we describe a case of infrarenal aortic hypoplasia in a 52-yr - old woman who presented with claudication . computed tomographic angiography revealed an abrupt absence of the infrarenal aorta , with collateral flow reconstituting the iliofemoral systems . after a polytetrafluoroethylene graft was interposed between...
every time we discuss about immunization program in adult and in elderly people , we should consider two important changes that happened in our current society : the increasing ageing of population and a different old age compared with the past . it has been estimated that since 2005 to 2030 world population over 65 ...
summaryvaccine - preventable disease significantly contributes to the morbidity and mortality of adults worldwide . the rates of vaccination against influenza , pneumococcal disease and tetanus in adults and in high - risk group of people are far from the optimal coverage as suggested by minister of health . genera...
substantial coronal and radicular tooth structure is lost as a result of endodontic therapeutic procedures . hence , endodontically treated teeth are known to present increased susceptibility for mechanical and biological failures than intact vital teeth . the higher risk of fracture is also attributed to other facto...
background : remaining dentin wall thickness may influence the fracture resistance of tooth.aims:to investigate the effect of various coronal dentin wall widths on the fracture strength of root canal treated teeth.materials and methods : fifty recently extracted single canal mandibular premolars were used for the study...
in refractory temporal lobe epilepsy ( tle ) , it is important to be able to determine which hemisphere is dominant and hosts the majority of the language areas . when a patient is evaluated as a potential candidate for resective surgery , language mapping should be able to indicate which hemisphere is dominant and p...
temporal lobe epilepsy ( tle ) in children is a slightly different entity than tle in adults not only because of its semiology and pathology but also because of the different approach to surgical treatment . presurgical investigations for eloquent cortex , especially language , must take these differences into accoun...
diabetes mellitus ( dm ) which is characterized by hyperglycemia is a common metabolic disorder that happens due to insulin deficiency and insulin resistance ( 1 ) . it is associated with central nervous system ( cns ) and peripheral nervous system ( pns ) neurological complication ( 2 ) . dm in long - term causes ...
diabetes mellitus is one of the most common causes of neuropathy . although antioxidant and antidiabetic effects of the aqueous extract of purslane ( portulaca oleracea ) ( aeop ) have been demonstrated before by other researchers , we did not find any study that assessed the psychobiological effects of aeop in diabe...
carbon nanotubes have been extensively studied because of their interesting physical properties and potential applications . motivated by this success , scientists have been exploring nanotubes and nanostructures made of different materials . in particular , theoretical studies have also been carried out to investi...
the symmetry properties of the single - walled bc2n nanotubes were investigated . all the bc2n nanotubes possess nonsymmorphic line groups . in contrast with the carbon and boron nitride nanotubes , armchair and zigzag bc2n nanotubes belong to different line groups , depending on the index n ( even or odd ) and the...
the online version of this article ( doi:10.1007/s00239 - 009 - 9239 - 0 ) contains supplementary material , which is available to authorized users . alpha-2-fucosyltransferases ( 2fts ) are enzymes required for the biosynthesis of the terminal glycan motif fuc2gal-r found in abh and lewis histo - blood group antigen...
the alpha-2-fucosyltransferases ( 2fts ) are enzymes involved in the biosynthesis of 2fucosylated glycan structures . in mammalian genomes , there are three 2 ft genes located in tandem fut1 , fut2 , and sec1each contained within a single exon . it has been suggested that these genes originated from two successive...
testosterone is the main androgen hormone and exerts its physiological effects through a genomic mechanism that is mediated by the androgen receptor . these non - genomic effects are considered to be rapid , in contrast to the genomic effects , and several possible pathways have been identified . the activation of ...
summarybackgroundandrogen abuse is an increasing problem amongst professional and amateur athletes . moreover , testosterone , apart from its widely accepted indications , is used for a variety of other indications such as aging and ischemia . its actions are mainly attributed to a specific genomic mechanism throug...
several important novel structures evolved in ancestral vertebrates , including a complicated nervous system equipped with integrated sensory systems , bones , and acquired immune systems . importantly , these novel structures probably did not evolve all at once , but via sequential steps . therefore , to understan...
it is now accepted that ancestral vertebrates underwent two rounds of genome duplication . here we test the possible utility of these genome duplication events as a reference time for the evolutionary history of vertebrates , by tracing the molecular evolutionary history of the genes involved in vertebrate neural cre...
recent advances in brain imaging techniques facilitate the investigation of brain activity levels during movement by unrestrained human subjects . imaging studies using single photon emission computed tomography and functional near - infrared spectroscopy ( fnirs ) have demonstrated that , in the frontal lobe , t...
to understand cortical mechanisms related to truncal posture control during human locomotion , we investigated hemodynamic responses in the supplementary motor area ( sma ) with quadrupedal and bipedal gaits using functional near - infrared spectroscopy in 10 healthy adults . the subjects performed three locomotor ta...
a total of 20,653 women delivered in our hospital between january 2002 and december 2010 . we did not include the women with known diabetes ( n = 204 ) or those for whom the status for either one of the five risk factors was not known ( n = 1674 ) . therefore , 18,775 pregnancies were analyzed . data are routinely ...
objectivewe aimed to evaluate a selective screening strategy for gestational diabetes mellitus ( gdm ) based on the presence of risk factors : bmi 25 kg / m2 , age 35 years , family history of diabetes , personal history of gdm , or birth of a child with macrosomia.research design and methodsof 20,630 deliveries betwee...
atrial fibrillation ( af ) is a common arrhythmia with an estimated clinical prevalence of approximately 1% in the general population and as high as 9% in individuals by the age of 80 years myocardial dysfunction observed in sepsis could contribute to arrhythmias and inflammation per se could induce or provoke af . ...
atrial fibrillation ( af ) is a common arrhythmia with an estimated clinical prevalence of approximately 1% in the general population and as high as 9% in individuals by the age of 80 years . the aetiology is multifactorial . systemic disease , e.g. , inflammatory processes , sarcoidosis , autoimmune disorders , ha...
when vaginal hysterectomy ( vh ) is not possible , many surgeons are reluctant to use laparoscopic techniques on obese patients and instead use the abdominal approach . current evidence suggests that there is no significant difference in outcomes for normal weight versus obese women undergoing laparoscopic hysterecto...
objective : our objective was to compare the surgical outcomes of obese women having hysterectomy according to the route ( abdominal , vaginal , or laparoscopic ) of the procedure.methods:a chart review of 293 hysterectomy procedures was performed . data were collected including operative and anesthesia time , estima...
posterior reversible encephalopathy syndrome ( pres ) relates to a transient pattern of brain edema mostly involving the parietal and occipital regions . severe hypertension may lead to pres when overcoming brain autoregulation with subsequent breakthrough brain edema . we describe a case of asymmetric pres associate...
we describe a case of asymmetric pres due to the presence of hyperplastic anterior choroidal artery ( acha ) in a man affected by sever hypertension . posterior reversible encephalopathy syndrome ( pres ) has become synonymous with a unique pattern of brain vasogenic edema and predominates in the parietal and occipit...
electrochemical water oxidation , also known as the oxygen evolution reaction ( oer ) , is a key energy conversion reaction in a number of clean energy technologies , including rechargeable metal air batteries , electrolysis cells , and solar fuel production . widespread commercialization of these technologie...
to develop active nonprecious metal - based electrocatalysts for the oxygen evolution reaction ( oer ) , a limiting reaction in several emerging renewable energy technologies , a deeper understanding of the activity of the first row transition metal oxides is needed . previous studies of these catalysts hav...
there is concern that older people with reduced respiratory muscle strength may be misclassified as having copd on the basis of spirometric results and receive unnecessary and potentially harmful treatment . with increasing age , the smaller pulmonary airways more readily collapse and forced vital capacity ( fvc ) , fo...
objectiveolder people with reduced respiratory muscle strength may be misclassified as having copd on the basis of spirometric results . we aimed to evaluate the relationship between lung function and grip strength in older hospitalized patients without known airways disease.methodspatients in acute medical wards wer...
focal choroidal excavation ( fce ) was first described by jampol et al1 as an anomalous excavation of the choroid ; it is typically observed by optical coherence tomography ( oct).1,2 this condition has been associated with several chorioretinal conditions and asymptomatic status , including central serous chorioretino...
we describe focal choroidal excavation ( fce ) in a case of vogt koyanagi harada ( vkh ) disease and compare the findings with different chorioretinal conditions . a 55-year - old man was diagnosed with vkh based on panuveitis and exudative retinal detachments . spectral - domain optical coherence tomography demo...
levocetirizine ( lcz ) , an active enantiomer of cetirizine , is a second - generation antihistamine that was approved by the us food and drug administration in 2008 for the relief of symptoms associated with allergic diseases in adults and children [ 1 - 3 ] . although it has some side effects such as sleepiness , ...
levocetirizine is a second - generation nonsedative antihistaminic agent that has been demonstrated to be safe and effective for treating allergic disease . there was only one case report of levocetirizine - induced liver toxicity , but a liver biopsy was not performed . in this article , we present the first case of...
bacterial vaginosis ( bv ) is a common condition causing various symptoms such as vaginal discharge , odor and irritation , and has been associated with increased acquisition of many sexually transmitted diseases [ 1 , 2 ] . pregnant women with bv have an increased risk of preterm labor and preterm delivery w...
the presence of semen in vaginal fluid , as identified by an acid phosphatase spot test , does not influence vaginal proinflammatory cytokine concentrations . objective : determine whether semen , as detected by acid phosphatase , influences vaginal cytokines or secretory leukocyte protease inhibitor concentrations ....
longipalpis were obtained from santarm and camar colonies , maintained at the department of entomology , oswaldo cruz foundation , rio de janeiro ( rj ) , brazil . salivary glands of three - five days - old non blood - fed adult female lu . longipalpis were dissected , transferred to microtubes containing p...
leishmania parasites expose phosphatidylserine ( ps ) on their surface , a process that has been associated with regulation of host 's immune responses . in this study we demonstrate that ps exposure by metacyclic promastigotes of leishmania amazonensis favours blood coagulation . l. amazonensis accelerates...
eligible patients were drawn from 2 truven marketscan databases : commercial claims & encounters and medicare supplemental & coordination of benefits . large selfinsured employers , health plans , hospitals , and medicare contribute claims data to these databases . the full population includes 26 million people an...
backgroundcardiac implantable electric devices are commonly used to treat heart failure . little is known about temporal and geographic variation in use of cardiac resynchronization therapy ( crt ) devices in usual care settings.methods and resultswe identified new crt with pacemaker ( crtp ) or defibrillator generat...
lateral elbow pain is common with a population prevalence of 1%3%.1 the peak incidence occurs at around 4050 years of age group and in women aged 4246 years , incidence increases to 10%.23 in the uk , the netherlands , and scandinavia , the annual incidence of lateral elbow pain in general practice is 4 - 7/1000 popula...
background : lateral elbow pain is common with a population prevalence of 1%3% . the study was a comparative trial to validate the efficacy of single injection of platelet - rich plasma ( prp ) for tennis elbow as compared with single injections of triamcinolone and placebo ( normal saline ) over a short term period....
arsenic is recognized as one of the most serious inorganic contaminants in soil and groundwater worldwide , with significant public health implications . arsenic often makes its way into soil and water courses by the natural processes of weathering and dissolution of minerals such as arsenian pyrite , fe(as...
reactive mineral water interfaces exert control on the bioavailability of contaminant arsenic species in natural aqueous systems . however , the ability to accurately predict as surface complexation is limited by the lack of molecular - level understanding of as water mineral interactions . in the present ...
the incidence of parenchymal brain metastasis ( pbm ) from primary systemic cancer has been increasing along with prolonged survival of the patients with cancer . recent report showed that up to 30% of cancer patients can be expected to develop pbm according to the types of primary cancer6,12 ) . a population - bas...
objectivethe objective of study is to evaluate the incidence of leptomeningeal carcinomatosis ( lmc ) in breast cancer patients with parenchymal brain metastases ( pbm ) and clinical risk factors for the development of lmc.methodswe retrospectively analyzed 27 patients who had undergone surgical resection ( sr ) and 15...
subarachnoid - pleural fistula ( spf ) is an abnormal communication between the subarachnoid and pleural spaces that normally can arise from blunt or penetrating trauma or as a complication of chest operation . this occurs infrequently following cardiothoracic surgery for lung or chest wall resection and closure of...
subarachnoid - pleural fistula ( spf ) is a rare complication of chest or spine operations for neoplastic disease . concomitant dural and parietal pleural defects permit flow of cerebrospinal fluid into the pleural cavity or intrapleural air into the subarachnoid space . dural injury recognized intraoperatively per...
thus , the high prevalence of olfactory dysfunction after surgery or head trauma has a great effect on overall quality of life . following head injury with a fracture across the cribriform plate , a minor blow to the occipital area may result in anosmia due to tearing or shearing of olfactory nerve filaments . the ...
olfactory dysfunction may influence the quality of life tremendously . this study investigated the strength of the human olfactory nerve at the frontal skull base using cadavers . a total of 180 olfactory nerves were examined in 90 human cadaveric heads . the cut edges of the olfactory nerves were pulled until th...
in the absence of telomerase , telomere shortening limits the replicative lifespan of human cells thus providing a stringent tumor suppressive mechanism . however if dna damage checkpoints are compromised , cells can continue to divide until the telomeres lose their end - capping function and are subjected to dna do...
telomere dysfunction and fusion play key roles in driving genomic instability and clonal evolution in many tumor types . we have recently described a role for dna ligase iii ( lig3 ) in facilitating the escape of cells from crisis induced by telomere dysfunction . our data indicate that lig3-mediated telomere fusio...
the renin - angiotensin - aldosterone system ( raas ) plays an important role in the control of cardiovascular and renal homeostasis by regulating vascular tone , blood pressure ( bp ) , and fluid volume [ 1 , 2 ] . angiotensin ii ( ang ii ) is a physiologically active component of the raas , produced via an enzy...
hypertensive mice that express the human renin and angiotensinogen genes are used as a model for human hypertension because they develop hypertension secondary to increased renin - angiotensin system activity . our study investigated the cellular localization and distribution of cox-1 , cox-2 , mpges-1 , and mpges-2 ...
extensive surgical resection is often abandoned on identification of wide and deep tumor invasion at the hilar bile duct intraoperatively , because it is difficult to achieve curative resection . on determining that curative resection of the perihilar cholangiocarcinoma is not possible , an intraoperative decision abou...
secure reconstruction of multiple hepatic ducts that are severely damaged by tumor invasion or iatrogenic injury is a challenge . failure of percutaneous or endoscopic biliary stenting requires lifelong placement of one or more percutaneous transhepatic biliary drainage ( ptbd ) tubes . for such difficult situations ...
structural genomics has been successful in determining the structures of many unique proteins in a high throughput manner . since 2001 , these efforts have resulted in more than 6,772 structure depositions to the pdb , 3,251 of which are from the nih - sponsored protein structure initiative ( psi ) centers . nevert...
structural genomics has been successful in determining the structures of many unique proteins in a high throughput manner . still , the number of known protein sequences is much larger than the number of experimentally solved protein structures . homology ( or comparative ) modeling methods make use of experimental...
polymers are pervasive throughout all aspects of the modern age and , as described by rolf mlhaupt , without polymers , modern life would be impossible because polymers secure the high quality of life and serve as pacemakers for modern technologies . consequently , the urge to find renewable resources to re...
ferulic acid ( fa ) , a bio - based resource found in fruits and vegetables , was coupled with a hydroxyl - amino acid to generate a new class of monomers to afford poly(carbonate amide)s with potential to degrade into natural products . l - serine was first selected as the hydroxyl - amino partner for fa...
electromagnetic interference ( emi ) is a transient disruption or alteration in a devices normal function caused by an external signal . in implantable cardiac rhythm devices , the lead creates a loop antenna allowing a magnetic field to induce a current between the lead and the generator . the power of the externa...
backgroundover 140 million ipads have been sold worldwide . the ipad2 , with magnets embedded in its frame and smart cover and 3 g cellular data capability , can potentially cause electromagnetic interference in implantable cardioverter defibrillators . this can lead to potentially lifethreatening situations in pat...
the content of each peptide flask was dissolved by addition of hepes buffer 100 mm , ph 7.4 ( a128 ) or ultrapure milli - q water ( a116 ) . the concentration of a was then measured by uv - visible spectroscopy ( 276 nm ( tyr10)=1410 m cm ) . uv - visible spectra were recorded on a biochrom libra s50 or a spec...
the accumulation of redox - active metal ions , in particular copper , in amyloid plaques is considered to the cause of the intensive oxidation damage to the brain of patients with alzheimers disease ( ad ) . drug candidates based on a bis(8-aminoquinoline ) tetradentate ligand are able to efficiently extract cu2 + f...
as obesity is becoming increasingly more prevalent in the united states , weight loss to reduce adipose tissue mass is strongly promoted as a means to decrease the disease risk associated with excess adiposity ( 5 , 57 ) . unfortunately , the majority of individuals who lose weight are unlikely to maintain the reduce...
research indicates that weight cycling , or yo - yo dieting is a common occurrence in overweight and obese populations . the long term negative health consequences of weight cycling are debated and it is unclear whether or not this weight change pattern poses a greater disease risk compared to obesity maintenance ....
complications of foot ulcers are the major cause of hospitalization and amputation in diabetic patients and lead to significant health care costs as evidenced by the fact that 2040% of health care resources are spent on diabetes - related diabetic foot [ 1 , 2 ] . diabetic foot syndrome ( dfs ) is defined , according...
diabetic foot ulcerations have been extensively reported as vascular complications of diabetes mellitus associated with a high degree of morbidity and mortality ; in fact , some authors showed a higher prevalence of major , previous and new - onset , cardiovascular , and cerebrovascular events in diabetic patients with...
down syndrome ( ds ) is the most common chromosomal aneuploidy in live births and a leading cause of mental retardation . prenatal detection of chromosomal anomalies , such as trisomy 21 , in cases with ds relies on invasive practices such as amniocentesis or chorionic villi sampling . these procedures are associat...
currently no specific biomarkers exist for the screening of pregnancies at risk for down syndrome ( ds ) . since a quantitative proteomic approach with isobaric labelling ( itraq ) has recently been suggested to be highly suitable for the discovery of novel plasma biomarkers , we have now used this method to ex...
nonsteroidal anti - inflammatory drugs ( nsaids ) are one of the most commonly prescribed classes of medication , and they are routinely employed for their analgesic , antipyretic , and antiinflammatory properties . because they are potent inhibitors of cyclooxygenase ( cox ) enzymes , they reduce the synthesis of pro ...
nonsteroidal anti - inflammatory drugs ( nsaids ) are nowadays widely used in ophthalmology to reduce eye inflammation , pain , and cystoid macular edema associated with cataract surgery . recently , new topical nsaids have been approved for topical ophthalmic use , allowing for greater drug penetration into the vitr...
t4 lysozyme , as a member of the lysozyme family produced by bacteriophage , breaks down the bacterial cell wall by catalyzing the hydrolysis of poly saccharide chains during infection of the bacteria . the enzyme specifically cleaves the glycosidic bonds connecting the repeating subunits of cell walls betwee...
conformational motions of proteins are highly dynamic and intrinsically complex . to capture the temporal and spatial complexity of conformational motions and further to understand their roles in protein functions , an attempt is made to probe multidimensional conformational dynamics of proteins besides the t...
pancreatic lipase immunoreactivity ( spec fpl ) is currently considered to be the most accurate blood test for the diagnosis of feline pancreatitis . in this study , we measured lipase activity in cats using a newer catalytic lipase assay of dry - chemistry system ( fdc - v - lip ) to determine the reference rang...
the results of cancer patient treatment in poland remain unsatisfactory . according to eurocare reports , polish oncology patients have a much lower chance of surviving 5 years after diagnosis than elsewhere in europe [ 1 , 2 ] . this problem , which undoubtedly reflects poland s low healthcare budget , has for seve...
cancer patient treatment in poland remains unsatisfactory when compared to that in other countries . in 2005 , this alarming situation prompted the polish government to launch the national program for combating neoplastic diseases ( npcnd ) . one part of this project was to improve the quality of oncology instructi...
the study took place at a 300-bed community hospital that is the primary hospital for an acgme - accredited 3-year internal medicine residency with 36 residents , approved by the institutional review board . as a mandatory part of the residency curriculum , all residents had received formal training in clue as detail...
backgroundin actual clinical practice as opposed to published studies , the application of bedside ultrasound requires a perception of need , confidence in one 's skills , and convenience.objectiveas the frequency of ultrasound usage is evidence to its perceived value in patient care , we observed the pattern of autono...
the human environment together with the biological processes contributes significantly to free radical production . when these free radicals overwhelm the antioxidant defense mechanisms , oxidative stress sets in with its deleterious effects that lead to cell injury , degenerative diseases , and compromised immune syst...
gongronema latifolium fruit has wide application in ethnomedicine , especially in maintaining healthy living and general body healing . we therefore investigated the antioxidant , immunomodulatory activities , and safety of its ethanol extract and fractions . the in vitro antioxidant activities of the extract and f...
sexual health education ( she ) has been recognized by international organizations as a human right , a necessity for development , and a promoter of equity . nevertheless , most young people do not receive sufficient education for their sexual lives . worldwide , earlier sexual maturity and marriage at later ages ma...
background : despite so many unmet sexual health education ( she ) needs of adolescents , socio - cultural challenges have caused this issue to be ignored in different scoieties . this study investigated iranian female adolescents experiences and perceptions with respect to she that they received at schools , and wha...
however , the exact mechanisms of vasoconstriction of pulmonary vessels during hypoxia ( hpv ) have not been identified yet . many investigators have reported the role of reactive oxygen species ( ros ) in hpv . however , there are conflicting results on whether ros decreases or increases during hpv . furthermore , t...
background : the mechanism of hypoxic pulmonary vasoconstriction ( hpv ) is still debatable . it has been proposed that reactive oxygen species ( ros ) might be involved in hpv . however , there is no special transporter for superoxide anion in the cell membrane and it may release from the cells via anion exchanger ....
osteoblastoma is a rare benign tumor that accounts for less than 1% of all bone tumors and most commonly involves the spine and sacrum of young individuals . less than 10% of osteoblastoma are localized to skull and nearly half of these cases affecting the mandible , especially the posterior segments . the first we...
the clinical facts and radiologic findings are very important in the diagnostic evaluation of jaw swellings , and must be considered along with histologic findings . osteoblastoma , an uncommon primary lesion of the bone that occasionally arises in the jaws , is one such lesion causing a localized jaw swelling . clin...
over 500 000 gene sequences have been discovered encoding glycoside hydrolases that are grouped into more than 130 families according to the carbohydrate active enzyme classification ( cazy : www.cazy.org ) . endo--1,2-mannosidases are eukaryotic proteins involved in n - linked glycan maturation , folding , ...
inhibitor design incorporating features of the reaction coordinate and transition - state structure has emerged as a powerful approach for the development of enzyme inhibitors . such inhibitors find use as mechanistic probes , chemical biology tools , and therapeutics . endo--1,2-mannosidases and endo--1,2-...
a previously healthy teenage girl , who had immigrated to oregon from mexico as an infant , sought care in january 2000 for progressively severe headaches of several months duration . autopsy showed no evidence of trauma , and results of a toxicology screening were negative . examination of the brain showed obstruc...
the unexpected death of a teenager from neurocysticercosis prompted an investigation of this disease in oregon . we found 89 hospitalizations , 43 newly diagnosed cases , and 6 deaths from 1995 to 2000 . at least five cases occurred in persons who had not traveled or lived outside the united states . enhanced sur...
pact suicides are those wherein two or more individuals mutually agree and execute to terminate their lives together . the usual profile of persons involved in pact suicides includes those females , older , married and of high social class . if one relies on the media reports , whenever two or more deaths occur toget...
pact suicides involving families have been reported in the scientific literature , but reports have been few from india . we report the case of a family , in which the father and three children had entered into a suicidal pact and executed it due to social reasons . a 41-year - old man , with no past psychiatric or s...
to report a case of corneal perforation associated with oral administration of erlotinib and its spontaneous healing after temporary discontinuation of drug treatment . a 65-year - old man with metastatic lung cancer was treated with erlotinib ( 150 mg / day ) , a specific tyrosine kinase inhibitor of the epidermal g...
purposeto report a case of corneal perforation associated with oral administration of erlotinib and its spontaneous healing after temporary discontinuation of drug treatment.case reporta 65-year - old man with metastatic lung cancer was treated with erlotinib ( 150 mg / day ) , a specific tyrosine kinase inhibitor of t...
a 23-year - old healthy female was admitted to our hospital with a new - onset tender bulge in her left groin , associated with subjective fevers and chills . four days prior to presentation , she noted a sudden protrusion in her left groin with associated pain . given worsening pain and intermittent nausea , she pre...
endometriosis is a common gynecologic disorder wherein ectopic endometrial glands and stroma are found at extrauterine sites . extrapelvic endometriosis is a well - documented , yet rare , disease entity that can affect almost any organ system . inguinal endometriosis is an extremely rare disease entity characteriz...
cell culture systems are instrumental in elucidating regulation of normal function and mechanisms of its perturbation by toxic substances . to this end , three applications of epithelial cells cultured with 3t3 feeder layer support are described . first , treatment of the premalignant human epidermal keratinocyte l...
lactic acid bacteria ( lab ) isolated from dairy products have received increased attention as a potential food preservative due to their antagonistic activity against many food born pathogen such as listeria monocytogenes . lab are widely distributed in the nature , they are typically involved in a large number of t...
in the present study , the antibacterial effect of 20 lactic acid bacteria isolates from a traditional cheese was investigated . 6 isolates showed antibacterial effect against gram positive bacteria . streptococcus thermophilus t2 strain showed the wide inhibitory spectrum against the gram positive bacteria . gro...