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Common side effect of colchicine among the following is
Colchicine inhibits the polymerization of tubulin into microtubules. The disruption of the microtubules probably leads to defective intracellular movement of impoant proteins, nutrients, and waste products Common side effects of colchicine include bloating, abdominal cramps, lactose intolerance, and diarrhoea. They can...
4
Neutropenia
Asthma
Fever
Diarrhea
Pharmacology
Other topics and Adverse effects
8cda239e-4db8-455b-83b1-d4c27fe78ac6
single
Blood supply of bronchogenic sequestration is:
Bronchogenic sequestration refers to a discrete area of lung tissue that lacks any connection to the airway system. It has abnormal blood supply arising from aoa.
1
Aoa
Pulmonary aery
Pulmonary Vein
Bronchogenic aery
Pediatrics
Congenital Malformations
d2fcd22b-6ee2-4d05-b2a0-bb2944d1a6d4
single
Which of the following is true regarding sampling?
Cluster sampling is cost effective. In stratified random sampling the population is divided into strata. Ref: Park, 20th Edition, Page 752
2
In simple random sampling the population is divided into strata
Snowball sampling is used for hidden population
Snowball sampling is used for hidden population More sample in systemic random sampling
Cluster sampling is less cost effective
Social & Preventive Medicine
null
a7156a0e-ece8-4484-8ee2-77b4b5a183dd
multi
True about NPCDCS is all, EXCEPT:
The NPCDCS program has two components viz. (i) Cancer & (ii) Diabetes, CVDs & stroke. These two components have been integrated at different levels as far as possible for optimal utilization of the resource. The activities at State, District, CHC and Sub Centre level have been planned under the programme and will be cl...
3
Separate centre for stroke, DM
Implementation in some 5 states over 10 district
CHC has facilities for diagnosis and treatment of CVD, Diabetes
Day care facilities are available at subcentre
Social & Preventive Medicine
null
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multi
Carbonic anhydrase inhibitor should not be given in:
Adverse effects of CA inhibitors: Acidosis, hypokalaemia, drowsiness, paresthesias, fatigue, abdominal discomfo. Hypersensitivity reactions-fever, rashes, sulphonamides also cause hypersensitivity reactions. so the combination of these two drugs is not recommended Bone marrow depression is rare but serious. It is contr...
1
Sulfonamide hypersensitivity
Glaucoma
High altitude sickness
Epilepsy
Pharmacology
Kidney
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single
A young man has recently been bitten by a stray dog. He has a penetrating wound to the right forearm. The dog is nowhere to be found. In the emergency room, the wound is cleaned with water and povidone-iodine solution. Which of the following is the most appropriate next step in management?
Rabies is transmitted through the saliva of infected animals. Once clinical signs develop, the disease is almost 100% fatal. Symptoms of rabies may include apathy as well as hyperexcitability. Finding Negri bodies in nerve cells of the brain in infected animals confirms the diagnosis. Polymerase chain reaction for dete...
2
start postexposure prophylaxis
contact the local public health professional for further advice
treat with oral doxycycline
treat with IV ceftriaxone
Medicine
Infection
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multi
A 68-year-old woman develops new symptoms of burning when voiding. She has no fever, chills, or back discomfort. Her urinalysis reveals numerous white cells and bacteria. Which of the following medical comorbidities is most likely to coexist in this patient?
Urinary tract infections (UTIs) are increased in diabetes mellitus as well as in pregnancy, sickle cell disease, polycystic disease, and structural abnormalities of the urinary tract.
3
anemia
exercise
diabetes mellitus
influenza
Medicine
Kidney
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single
Secreting active thyroid follicles are lined by which type of epithelium ?
Ans. is 'a' i.e., ColumnarThis question is different from the one which was asked in session- 3.Here the examiner is asking about lining of thyroid follicles, which are secreting actively.Normally, thyroid follicle is lined by low couboidal epithelium. But, when they are active, their lining is tall columnar like."When...
1
Columnar
Cuboidal
Squamous
Pseudostratified squamous
Anatomy
null
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single
Mania is a
According to ICD-10 mood disorders are classified as Manic episodes Depressive episodes Bipolar mood disorder Recurrent depressive disorder Persistent mood disorder Other mood disorders (including mixed effective episodes and recurrent brief depressive disorder) (Ref: a sho textbook of psychiatry, Niraj Ahuja, 7th edit...
1
Mood disorder
Psychological Disorder
Obsessive disorder
Neurotic disorder
Psychiatry
Mood disorders
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single
Necrotising fasciitis includes
null
4
Skin
Fascia
Muscle
All of the above
Surgery
null
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multi
All of the following is associated with gastric carcinoma EXCEPT
(D) Blood group B FACTORS ASSOCIATED WITH INCREASED INCIDENCE OF GASTRIC CARCINOMAEnvironmental FactorsHost FactorsGenetic* Infection by H. pylori* Present in most cases of intestinal-type carcinoma* Diet* Nitrites derived from nitrates (water, preserved food)* Smoked and salted foods, pickled vegetables* Lack of fresh...
4
H. pylori infection
Smoking
Nitrates
Blood group B
Pathology
Misc.
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The commonest cause of cataract –
Most common type of cataract is senile (age-related) cataract.
4
Hereditary
DM
Trauma
Age related
Ophthalmology
null
f1c9e71f-af9c-4142-ab4d-d43f1634abcf
single
Which is the principal virulence factor in C. tetani?
Tetanospasmin referred to as tetanus toxin, is the neurotoxin that causes the manifestations of tetanusClostridium tetani:General characteristicsCultural characteristics--Strict anaerobe, gram-positive bacilli--Stately motility--Spherical terminal spores--Drumstick appearance--Swarming growth --Blood agar - a hemolysis...
2
Tetanolysin
Tetanospasmin
Tetanotactin
Immobility factor
Microbiology
Bacteriology
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single
Which of the following structure does not pass through diaphragm?
Ans. D Cisterna chyliRef Clinically Oriented Anatomy by Keith, Moore, 5th ed. pg. 387; Gray's Anatomy 40th ed. pg. 180* The cisterna chyli is a normal anatomical structure seen as saccular area of dilatation in the lymphatic channels that is located in the retrocrural space, usually to the immediate right of the abdomi...
4
Aorta
IVC
Esophagus
Cisterna chyli
Anatomy
Abdomen & Pelvis
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single
In molecular cloning, Blue-white screening is used for
The blue-white screen is a screening technique that allows for the rapid and convenient detection of recombinant bacteria in vector-based molecular cloning experiments. DNA of interest is ligated into a vector.The vector is then inseed into a competent host cellble for transformation, which are then grown in the presen...
3
To screen for recombinant vectors
To detect gene mutations
To identify desired chromosal DNA inse in plasmid vectors
To detect host DNA in situ
Biochemistry
Metabolism of nucleic acids
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single
What is not the management of a 1.6 cm bulbar urethral stricture in a patient with h/o pelvic fracture?
Management of patients of urethral stricture:1. Dilatation2. Optical internal urethrotomy at 12"0 clock Position - only performed for sho bulbar stricture3. If length of stricture up to 2cm - Excisions with end to end Anastomoses4. If length of stricture > 2cm - Excision with tissue transfer for reconstruction (Buccal ...
4
Dilatation with a catheter
Internal Urethrotomy
Excision followed by end-to-end urethroplasty
Excision f/b reconstruction using buccal mucosa
Surgery
Urethra and penis
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A 72-year-old female presents with complaints of generalized lymphadenopathy. Her CBC showed total WBC count of 80,000. Flow cytometry revealed CD19 CD20, CD 5 +, CD 23 -ve. Cyclin D1 + GI examination was done and biopsy was taken. Peripheral blood smear Which of the following genetic abnormality one may expect to find...
1st image shows the small to intermediate sized cells with cleaved nuclei. 2nd image shows Lymphomatoid polyposis. Mantle cell lymphoma is a B cell lymphoma with CD5+ but CD 23-ve. It shows cyclin D1 positivity and lymphomatoid polyposis. t(11:14) leads to overexpression of cyclin D1- involved in mantle cell lymphoma. ...
3
t(8:21)
13q deletion
t(11:14)
t(11:18)
Anatomy
Integrated QBank
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In chronic alcoholism the rate limiting component for alcohol metabolism excluding enzymes is / are:
NAD
2
NADP
NAD
null
FADH
Biochemistry
null
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multi
All are advantages of split thickness skin graft except
null
3
good uptake
reusable donor site
less contraction
large grafts can be harvested
Surgery
null
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multi
The tourniquet test is positive if the petechiae are more than:
Ans. D: 20 petechiae per square inch Dengue fever and dengue hemorrhagic fever (DHF) are acute febrile diseases and caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae. Dengue is transmitted to humans by the Aedes aegypti (rarely Aedes albopictus) mosquito, which feeds during the...
4
50 petechiae per square inch
40 petechiae per square inch
30 petechiae per square inch
20 petechiae per square inch
Medicine
null
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single
Hassals corpuscles are seen in :
A i.e. Thymus
1
Thymus
Spleen
Lymph node
Appendix
Anatomy
null
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single
Water -lily sign is seen in
(Complicated hydatid disease) (400 Grainger's diagnostic radiology 4th)Hydatid disease of lung - lower lobes affected in 60% cases* Calcification of cyst wall is rare and seen only in 0.7% cases* When a mediastinum, vertebral erosion in addition to rib erosion may occur with posterior mediastinum being affected in 65% ...
2
Hamartoma
Complicated hydatid disease
Cavitatory lesion in metastasis of the lung
Aspergillosis
Medicine
Infection
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single
Which one of the following is a prodrug?
Few drugs are inactive as such and need conversion in the body to one or more active metabolites. Such a drug is called a prodrug Enalapril is conveed to Enalaprilat (active form) so its a prodrug Prednisolone, Dopamine ,Ampicillin are present in active form Ref-KD Tripathi Pharmacology 7th edition(page no;22)
2
Dopamine
Enalapril
Ampicillin
Prednisolone
Pharmacology
General pharmacology
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single
Features of hypocalcemia are A/E -
null
3
Numbness & tingling
Circumoral paresthesis
Depressed tendon reflexes
Skin irritability & sensitivity
Medicine
null
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single
WHO criteria for semen analysis, which of the following is the only TRUE statement
World Health Organization reference values: Semen volume: 1.5 ml or more pH: 7.2-7.8 Sperm concentration: 15 million spermatozoa per ml or more Total sperm number: 39 million spermatozoa per ejaculate or more ( Range 36-42 million /ml) Total motility : 40% or more motile or 32% or more with progressive motility Round c...
4
Progressive motility >15%
Normal morphology >25%
Volume of 2-5ml
Sperm count >39million
Gynaecology & Obstetrics
Infeility (Eggs'plantation!)
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multi
Mathematical representation of inverse square law is
null
2
I2/I1 = (D2)2 / (D1)2
I1/I2 = (D2)2 / (D1)2
I2/I1 = (D2) / (D1)
I1/I2 = (D2) / (D1)
Radiology
null
b2424b79-d471-4682-acc8-3f0f16ae61e4
single
Which of the following condition shows cystic glandular hyperplasia of all the endometrial components microscopically?
Metropathia haemorrhagica or cystic glandular hyperplasia or Schroeder's disease is a type of abnormal bleeding, usually met in premenopausal women. The basic pathology may lie in the ovaries or may be due to disturbance of the rhythmic secretion of the gonadotrophins. There is slow increase in secretion of estrogen bu...
4
Menorrhagia
Polymenorrhea
Oligomenorrhea
Metropathia haemorrhagica
Gynaecology & Obstetrics
null
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multi
NCPF is due to
Pathology of Non-cirrhotic poal fibrosis Characterized by fibrous intimal thickening of the poal vein or its branches Hallmark of disease is thrombosis/sclerosis of the poal vein branches Poal and peripoal fibrosis of varying extent (No bridging fibrosis) Poal vein is dilated with sclerosis of the walls and in autopsy ...
2
Extrahepatic obstruction
Intrahepatic pre sinusoidal obstruction
Intrahepatic sinusoidal obstruction
Intrahepatic post sinusoidal obstruction
Anatomy
G.I.T
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single
For a girl of 18 years, site for X-ray to determine her age is: PGI 07
Ans. Wrist
2
Elbow
Wrist
Knee
Ankle Joint
Forensic Medicine
null
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single
Malignant otitis externa is -
null
4
Malignancy of external ear
Caused by hemophilus influenzae
Blackish mass of aspergillus
Pseudomonas infection in diabetic patient
ENT
null
4865b3a2-69d3-422c-a3df-d6b06f8045d7
single
Which of the following is not an ototoxic drug ?
Ans. is 'b' i.e., Penicillin G Impoant ototoxic drugs o Aminoglycosides o Cisplatin o Furosemide o Deferoxamine o Quinine o Chloroquine o Interferons o Erythromycin o Bleomycin o Aspirin
2
Neosporin
Penicillin G
Kanamycin
Cisplatin
Pharmacology
null
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single
All of the following 'Reforms' have been proposed by the World Health Repo (2008), except -
Ans. is 'd' i.e. Economic Reforms
4
Service Reforms
Leadership Reforms
Policy Reforms
Economic Reforms
Social & Preventive Medicine
null
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multi
In Werner Syndrome, the most common site of Gastrinoma is?
"Gastrinomas are either associated with MEN I syndrome (30%) or sporadic (70%). Duodenal gastrinomas is the most frequent site for both the forms” Most gastrinomas (50-70%) are present in the duodenum, followed by the pancreas (20-40%) and other intraabdominal sites (mesentery, lymph nodes, biliary tract, liver, stomac...
3
Pancreas
Stomach
Small Intestine
Colon
Pathology
null
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multi
A 70 year old man is diagnosed to have Legionnaire's disease after he returns home attending a convention. He could have acquired it:
Legionnaires' disease is the designation for pneumonia caused by Legionella. Inhalation of the aerosol in the air-conditioned room is a proposed mode of acquiring this infection. However according to Harrison "Cooling towers and evaporative condensers have been overestimated as sources of Legionella. In many outbreaks ...
3
From a person suffering from the infection while travelling in the aeroplane
From a chronic carrier in the convention center
From inhalation of the aerosol in the air-conditioned room at convention center
By sharing an infected towel with a fellow delegate at the convention
Microbiology
null
4816f6a2-0d51-4bb1-a2bc-09e7955479f6
single
All are seen in acute Iridocyclitis except –
Pain, ciliary (circumcorneal) congestion and small pupil (meiosis) are seen in acute anterior uveitis. There is watery discharge (not mucopurulent). Mucopurulent discharge is seen in acute conjunctivitis, an important differential diagnosis of acute anterior uveitis.
3
Pain
Ciliary congestion
Mucopurulent discharge
Small pupil
Ophthalmology
null
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multi
Episodic generalized weakness can occur due to all of the following acute electrolyte disturbances, except :
Answer is B (Hypocalcemia): Episodic generalized weakness is associated with hypercalcemia and not Hypocakemia.
2
Hypokalemia
Hypocalcemia
Hyponatremia
Hypophastemia
Medicine
null
4d6e4b1d-4457-4c88-8e77-b60dd4aa545d
multi
Drug of choice for treatment of Steroid Resistant Nephrotic syndrome is:
Drug of choice for treatment of Steroid Resistant Nephrotic syndrome is: Calcineurin inhibitors (Cyclosporine or Tacrolimus)
4
Prednisolone
Levamisole
Cyclophosphamide
Cyclosporine
Pediatrics
Nephritic & Nephrotic Syndrome
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single
Persistent priapism is due to
Ans. is 'a' i.e., Sickle cell anemia Priapism is defined as erection lasting for > 4 hours. Low-flow priapism may be due to any of the following: An excessive release of neurotransmitters Blockage of draining venules (eg, mechanical interference in sickle cell crisis, leukemia, or excessive use of intravenous parentera...
1
Sickle cell anaemia
Hairy cell leukaemia
Paraphimosis
Urethral stenosis
Medicine
null
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single
Antifungal drug used for systemic fungal infection is -
Ans. is 'c' i.e., Amphotericin B
3
Griseofulvin
Clotrimazole
Amphotericin B
Econazole
Pharmacology
null
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single
Which of the following is appropriate first-line medical therapy for hypeension with pheochromocytoma in pregnancy?
Immediate control of hypeension and pheochromocytoma symptoms with an alpha blocker such as phenoxybenzamine is imperative. The dose is 10 to 30 mg, two to four times daily. After alpha-blockade is achieved, beta -blockers may be given for tachycardia if necessary.
3
Calcium-channel blockers
b -Blockers
a-Blockers
Apresoline
Gynaecology & Obstetrics
Pregnancy induced Hypeension
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single
A 32 week pregnant multigravida found to have abnormal glucose tolerance test and diagnosed as gestational diabetes. All of the following can be the complications in this newborn, EXCEPT:
Similar to pre gestational diabetes, GDM is associated with an increased risk of maternal and fetal complications including preeclampsia, stillbih, and macrosomia. Infants born to mothers with gestational diabetes are at increased risk of hypoglycemia, hyperbilirubinemia, hypocalcemia, and RDS.Offspring of mothers with...
2
Hyperbilirubinemia
Hyperglycemia
Hypocalcemia
Hypomagnesemia
Pediatrics
null
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multi
Indicated technique for histopathological examination of utrine cancer for mass screening.
null
1
Exfoliative cytology.
Brush cytology
FNAC
None of the above
Surgery
null
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multi
Decreased level off serum Vit B6 is seen ina) CRFb) CHF c) INH therapyd) Alcohol
null
3
ab
bc
cd
ac
Medicine
null
522aca8b-1d5a-492c-8f5b-fa78cb20d61d
single
True about Laron dwarfism is:
Laron dwarfism, Plasma GH is normal or elevated GH receptors are unresponsive as a result of loss-of-function mutations of the gene for the receptors. Resultsin growth hormone insensitivity. Plasma IGF-I is markedly reduced, along with IGFBP 3 (IGF-binding protein-3)
2
Growth hormone deficiency
Growth hormone insensitivity
Plasma IGF-1 is markedly increased
Plasma IGF-BP3 at normal levels
Physiology
Endocrine System
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multi
PCT absorbs all except:
PCT reabsorbs all of the filtered glucose and amino acids. PCT reabsorbs largest fraction (about 67%) of the filtered Na+, K+, Ca2+, Cl-, HCO3-, and water H+ is secreted by the PCT; it is for the re-absorption of the filtered HCO3-. Fluid at the end of the PCT is always Iso-osmotic to plasma. Glomerulotubular balance i...
3
Sodium
Glucose
Hydrogen ions
Amino acids
Physiology
Excretory System (Kidney, Bladder) Acid-Base Balance
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3rd person hallucinations are characteristic of:March 2011
Ans. B: SchizophreniaFRS of schizophrenia includes: Voices heard arguing: Two or more hallucinatory voices discussing the subject in third personSchizophrenia:First rank symptoms:HallucinationDelusional perceptionThought alienation phenomenon:Thought withdrawlThought inseionThought broadcastingPassivity phenomenonBleul...
2
Depression
Schizophrenia
Obsession
Mania
Psychiatry
null
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multi
Chalcosis is deposition of:September 2010, March 2013
Ans. C: CopperA deposit of fine paicles of copper in the lungs or other tissues is known as chalcosis.
3
Iron
Calcium
Copper
Lead
Pathology
null
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single
Congenital toxoplasmosis–False is –
null
4
Diagnosed by detection of IgM in cord blood
IgA is more sensitive than IgM for detection
Dye test is gold standard for IgG
Avidity testing must be done to differentiate between IgA & IgM
Pediatrics
null
b4a446b7-0d3e-48e5-af51-449807d209ec
multi
During autopsy, If spinal cord is to be examined what is the most commonly used approach -
To examine spinal cord the body is placed in prone position with head downwards. A wooden block is placed under chest and head is bent downwards. A midline incision is made from occipital protuberance to fouh lumbar veebra. Dr. Narayana Reddys Synopsis of Forensic Medicine & Toxicology 27 th edition pg. 60.
2
Anterior
Posterior
Lateral
Antero-lateral
Forensic Medicine
Death and postmortem changes
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single
Which is FALSE about horse-shoe kidney: March 2004
Ans. A i.e. Spider like appearance in IVP
1
Spider like appearance in NP
Ureteral obstruction is common
Lower calyx reversed
Not a contraindication to pregnancy
Surgery
null
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A child in status epilepticus should not be given
Seizures are one of the adverse effects of clonazepam Drugs Commonly Used In Status Epilepticus*Lorazepam *Midazolam*Diazepam*Phosphenytoin*Paraldehyde*Phenobarbital*Pentobarbital *Propofol*Thiopentone*ValproateSteps in management of status epilepticusIV Diazepam 0.1-0.3 mg/kg (or)Lorazepam 0.05-0.1 mg/kg|Fosphenytoin ...
1
Clonazepam
Phos Phenytoin
Phenobarbital
Diazepam
Anatomy
All India exam
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single
GV Black simply classified cavities as:
null
3
Two classes of smooth surface and three classes of pit and fissure lesions
Three classes of smooth surface and two classes of pit and fissure lesions
One class of pit and fissure and four classes of smooth surface lesions
None of the above
Dental
null
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multi
All of the following drugs are harmful in pregnancy except
Heparin does not cross the placenta. Hence it is safe for use in pregnant patients who needs anticoagulation.Ref: Katzung 13th ed Pg 589
4
Phenytoin
Diazepam
Warfarin
Heparin
Pharmacology
Other topics and Adverse effects
47a17120-8318-4f6c-b7fa-e325c70df3fe
multi
Posterior cruciate ligament prevents the following action of the tibia on femur?
Functions of posterior cruciate ligament:Stabilises kneePrevents posterior dislocation of the tibia on femurLimits hyper extension of knee only if the anterior cruciate is rupturedFunction of ACL: Prevents anterior dislocation of the tibia on femur Ref: BDC, 4th Volume, 2/145
2
Anterior dislocation
Posterior dislocation
Rotation
Limit hyperflexion
Anatomy
null
d2a58b1b-f3f0-4cf0-b7f7-1f1b8b0de990
single
Food causes reflex defecation-
Ans. is 'c' i.e., Gastrocolic reflex * From the cecum to the sigmoid colon mass movement (mass peristalsis or mass contraction) occurs. These movements usually occur only one to three times each day. A mass movement is a modified type of peristalsis.* Appearance of mass movements after a meal is facilitated by gastroco...
3
Enterogastric reflex
Defecation reflex
Gastrocolic reflex
Rectoanal reflex
Physiology
G.I.T.
02829364-5cd0-4ed8-9753-82c7c8de6e11
single
Which is true about the dislocation of hip joint?
Posterior dislocation is the commonest dislocation. Posterior dislocation has typical deformity of flexion, adduction and internal (medial) rotation. Anterior dislocation has deformity of flexion, abduction and external (lateral) rotation.
4
Posterior dislocation is commoner
In posterior dislocation whole lower limb is rotated medially
In anterior dislocation whole lower limb is rotated laterally
All of the above
Orthopaedics
null
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multi
A boy presents with diplopia and restriction of eye movements following blunt trauma to his eye. X- ray reveals blow out fracture of orbit. Which part of orbit is most likely damaged -
Blow out fracture mainly involve orbital floor (inferior wall) & medial wall.
2
Superior wall
Inferior wall
Lateral wall
Medial wall
Ophthalmology
null
88378383-4290-43ec-8106-2c14cfe72565
multi
Effect of GL P-1-
Ans. is 'c' i.e., Increased insulin secretion from beta-cells of pancreas o Recently, attention has been focused on glucagon - like polypeptide 1 (7-36) (GLP-1 ) as an additional gut factor for insulin secretion and GLP-1 (7-36) is more potent tnsulinotropic hormone.Regulation of insulin secretiono Factors affecting in...
3
Increased aldosterone secretion by adrenal
Increased PTH secretion
Increased insulin secretion from beta-cells of pancreas
Increased testosterone secretion from Ley dig cells
Physiology
Endocrinology metabolism
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single
The treatment of a patient with myocardial infarction is thrombolytic therapy, if the patient presents within ---- hours of Chest pain -
null
4
6 hours
12 hours
18 hours
24 hours
Medicine
null
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single
A 50-year-old man presents with feeling tired and unsteady on his feet. He has a poor appetite and has lost 10 lb. On examination, he appears cachectic, his heart and lungs are normal, but his liver span is 18 cm. His lab tests show a very low magnesium level (0.7 mEq/L). On further questioning, he reports drinking hea...
Magnesium deficiency is most commonly due to alcoholism. Renal loss and malabsorption are also common causes. Magnesium deficiency is not seen in hypervitaminosis E. Causes of magnesium deficiency also include milk diets in infants, the diuretic phase of acute tubular necrosis, chronic diuretic therapy, acute pancreati...
1
alcoholism
chronic malabsorption
diabetes mellitus (DM)
kwashiorkor
Medicine
Endocrinology
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single
One TB infected person can infect how many people in 1 yr -
An estimated annual average of 10-15 persons contact the infection from one case of infectious pulmonary TB. Ref: PARK&;S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 23rd edition , Page :181
3
20
30
10
5
Social & Preventive Medicine
Communicable diseases
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single
ISO has classified instrument on the basis of
null
1
Method of use
Use of instrument
Newer instruments
Cutting efficiency
Dental
null
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single
The exercise-induced hyperventilation during vigorrous exercise is produced due to the receptors present in
The exercise-induced hyperventilation during vigorous exercise is produced due to the receptors present in carotid bodies. When exercise becomes more vigourous,, buffering of the increased amounts of lactic acid that are produced liberates more CO2, and fuher increases ventilation. The additional increase in ventilatio...
3
Medulla oblongata
Lung parenchyma
Carotid bodies
Trachea and large bronchi
Physiology
Respiratory system
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single
In an after coming head the following bone is perforated during craniotomy :
Craniotomy : It consists of perforating the fetal skull, evacuating the contents and then delivering rest of the fetal pas Indications: Delivery of dead fetus in obstructed labour with a cephalic presentation Delivery of the arrested after coming head in vaginal breech delivery Hydrocephalus Ref: Datta Obs 9e pg 544.
1
Occiput
Parietal
Palate
Frontal
Anatomy
Abnormal labor
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single
Most sensitive and specific test for diagnosis of iron deficiency is
Ref Harrison 19 th ed pg 627,628 Under steady-state conditions, the serum ferritin level correlates with total body iron stores; thus, the serum ferritin level is the most convenient laboratory test to estimate iron stores. The normal value for ferritin varies according to the age and gender of the individual
2
Serum iron levels
Serum ferritin levels
Serum transferrin receptor population
Transferrin saturation
Anatomy
Haematology
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single
Nerve involved in exposure keratopathy: September 2009
Ans. C: Seventh cranial nerve Exposure keratitis may occur in any condition in which the ocular surface is not properly lubricated and covered by the eyelids. The most common conditions associated with the development of exposure keratitis include Bell's palsy, exophthalmos associated with Grave's disease, and ectropio...
3
Third cranial nerve
Fifth cranial nerve
Seventh cranial nerve
Ninth cranial nerve
Ophthalmology
null
9e2a6e92-9682-46d1-ad10-bc61d42992c3
single
A baby born to a couple who are 45 years each is at higher risk of development of:
Klinefelter syndrome Male hypogonadism that occurs when there are two or more X chromosomes and one or more Y chromosomes. Elderly maternal and paternal age are associated with multiple genetic condition. Due to defective gametogenesis which has higher chance of occurrence in older age. Age Syndrome Older age of father...
3
Down syndrome
Marfan syndrome
Klinefelter syndrome
Osteogenesis imperfecta
Pathology
Specific Cytogenetic Disorders
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single
Most common cause of abnormality in first trimester abortion
(Chromosomal anomaly) (161 - Dutta 6th)Common Causes of AbortionFirst Trimester -1. Genetic factor (50%) of early miscarriage are due to chromosomal abnormality in the conceptus, Autosomal trisomy is the commonest (50%) cytogenic abnormality2. Endocrine disorders (LPD) thyroid abnormalities DM3. Immunological disorders...
2
Cervical incompetance
Chromosomal ahnormolity
Placental & membrane abnormality
Retroversion
Gynaecology & Obstetrics
Miscellaneous (Gynae)
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single
Which of the following is NOT a characteristic of Carcinoma esophagus?
Adenocarcinoma and squamous cell carcinoma are the two common type of carcinoma esophagus. Other rare type of esophageal carcinoma include undifferentiated, carcinoma, malignant melanoma, lymphoma and sarcoma. Middle one third is most common site of carcinoma and is involved in about 60% of esophageal cancers. Dysphagi...
4
Adenocarcinoma
Middle one third affected
Dysphagia
Pernicious anemia often present
Surgery
null
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single
Meiotic crossover occurs in which of the following?
Crossover occurs during the pachytene stage of meiosis. Meiosis is the mechanism used by the reproductive organs to generate gametes-cells with the haploid number of chromosomes. DNA synthesis occurs before meiotic prophase begins and is followed by a G2 phase. Cells then enter meiotic prophase I. During meiotic propha...
3
Leptotene
Zygotene
Pachytene
Diplotene
Unknown
null
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single
Nasolacrimal duct opens into: (Repeat)
Ans: A (Inferior meatus) Ref: Gray's Anatomy, 40th edition. pg. 550Explanation:Lateral wall of the nose has 3 concha 3 meatusThe inferior concha is an independent bone.The space under cover of the inferior concha is known as the inferior meatus- largest meatusDuring postnatal development, the ostium of the nasolacrimal...
1
Inferior meatus
Superior meatus
Middle meatus
Sphenoethmoidal recess
Anatomy
Nose
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single
During application of the cup in Ventouse, 'knob' of the cup points towards: March 2013
Ans. D i.e. Occiput Ventouse Indications As an alternative to forceps operation. Deep transverse arrest with adequate pelvis Delay in descent of head of the second baby of twins Delay in first stage due to uterine ineia or primary cervical dystocia Contraindications Prematurity Head not engaged Fetal distress Pelvic co...
4
Brow
Chin
Neck
Occiput
Gynaecology & Obstetrics
null
908238a1-ca91-4ace-996b-38455d840b3e
single
A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting hea rate was 96/min blood pressure 170/104 mm Hg, but blood sugar level and lipid profile were normal. Select the most suitable antihypeensive for the initial therapy in his case:
(Ref: KDT 6/e p544) Tense personality and high resting hea rate (96/min.) makes b-blockers ideal candidate drugs to be used in this case. As blood sugar and lipid profile is normal, beta blockers can be used safely.
3
Nifedipine
Hydrochlorothiazide
Atenolol
Methyldopa
Anatomy
Other topics and Adverse effects
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single
A pathologist examines a renal biopsy from a 45 year old man with nephrotic syndrome and requested a congo red stain to confirm the nature of an amorphous acidophillic extracellular hyalin substances localized within the mesengial matrix of the glomeruli A positive test confirms the presence of
The answer is B. A positive congo red test confirms the presence of amyloid. Apple green birefringence is abserved under polarized light.
2
α 1 - antitrypsin
Amyloid
Copper
Glycogen
Pathology
null
2fc0d4b1-0333-422d-bea1-9bbbd119c9cb
single
In a patient with urethral syndrome, urine microscopy shows full of polymorph, but no bacteria. The most appropriate culture medium is__
The clinical picture is suggestive of Chlamydial infection hence the most appropriate culture medium is McCoy cells(human synol carcinoma cell line). Abnormal urethral Gram's stains showing >10 PMNs/1000A~ field in women with dysuria but without coliform bacteriuria suppo the diagnosis of chlamydial urethritis. Thayer-...
2
PPLO broth
McCoy cells
Robeson's cooked meat
Thayer main agar
Microbiology
Bacteriology
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single
Intrauterine fetal distress is indicated by:a) Acceleration of 15/minb) Deceleration of 30/minc) Variable deceleration 5-25/mind) Fetal HR<80/mine) Fetal HR 160-180/min
Fetal distress is an ill-defined term, used to express intrauterine fetal jeopardy, as a result of intrauterine fetal hypoxia. Indicators of Fetal Distress:
3
bce
abd
bcde
acde
Gynaecology & Obstetrics
null
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single
Aspiration of sperms from testes is done in :
Ans. is a i.e. TESA Friends, we have studied in detail IVF and IUI but either of them cannot be performed if appropriate methods for sperm recovery are not available in cases of male infeility. Sperm retrieval or Recovery can be done by : Microsurgical Epididymal Sperm aspiraton : MESAdeg Percutaneous Epididymal Sperm ...
1
TESA
MESA
ZIFT
GIFT
Gynaecology & Obstetrics
null
fca08fb1-11e0-434a-bf1f-91d6244e3540
single
Anterior lymphatics from nose drain into
Lymphatics from the anterior half of the lateral wall pass to the submandibular nodes, and from the posterior half, to the retropharyngeal and upper deep cervical nodes Anterior half of Nasal septum to the submandibular nodes. Posterior half of nasal septum to the retropharyngeal and deep cervical nodes . Ref - BDC vol...
3
Pretracheal nodes
Submandibular nodes
Deep cervical nodes
Submental nodes
Anatomy
Head and neck
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single
Which one of these is absorbed in ileum?
Vitamin B12 is predominantly absorbed in ileum Ref: guyton and hall textbook of medical physiology
2
Vitamin D
B12
Iron
Fat
Physiology
G.I.T
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single
Cherry red color of hypostasis is seen in-
Cherry red color of blood is characteristically found in CO poisoning and in about 50% cases in cyanide/HCN poisoning (in 50% cases of cyanide poisoning it is bright red colored).
1
CO poisoning
H2SO4
HNO3
Burns
Forensic Medicine
null
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single
Among the toxins produced by clostridium botulinum the non-neurotoxic one is -
null
4
A
B
C1
C2
Medicine
null
883f8ed7-af4b-4e71-91c1-275cedf5be9b
single
Epiphyseal plate fractures are classified by: September 2005
Ans. B: Salter-Harris Classification Salter-Harris classification (Type with the structure involved): Type I: The entire epiphysis Type II: Entire epiphysis + poion of the metaphysis Type III: Poion of the epiphysis Type IV: Poion of the epiphysis +poion of the metaphysis Type V: Nothing "broken off;" compression injur...
2
Herring's classification
Salter-Harris classification
Garden's classification
Pauwel's classification
Surgery
null
9dd107f1-6064-41b2-bd44-fe1d828516ce
single
A young man repos with history of 6 kg weight loss in 3 month and on examination found to have generalized lymph node enlargement. Likely possibilities are following EXCEPT -
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases it can cause yellow skin, seizures, coma, or death.Symptoms usually begin ten to fifteen days after being bitten by an infected ...
3
HIV-AIDS
Lymphoma
Chronic malaria
Disseminated tuberculosis
Medicine
Miscellaneous
37658109-810a-47de-983e-0612b866cd3b
multi
Epalrestat is used in
It is a aldose reductase inhibitor. Thereby it prevent conversion of glucose in to sorbitol. Sorbitol act like a tissue toxin & is responsible for many of the complica on of diabetes. So Epalrestat is use as a drug to prevent the complica on of diabetes. But it does not reduce the blood sugar level.
4
Hypeension
Hyperlipidemia
HIV
Diabetes
Pharmacology
All India exam
443b0936-1c78-4eed-8c4e-a31e907fedc3
single
Which of the following does not contain fat on mammography?
Fat containing breast lesions are Lipoma, Galactocele, Hamartoma, Traumatic lipid cyst (fat necrosis), oil cyst.
3
Post – traumatic cyst
Hamartoma
Seborrhea keratosis
Galactocele
Radiology
null
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single
Which of the following substances crosses capillary walls primarily through water-filled clefts between the endothelial cells?
Because O2, CO2 and CO are lipophilic, they cross capillary walls primarily by diffusion through the endothelial cell membranes. Glucose is water soluble; it cannot cross through the lipid component of the cell membrane and is restricted to the water-filled clefts, or pores, between the cells.
4
O2
CO2
CO
Glucose
Physiology
Transpo Processes
d8d74a40-9015-48cb-a48f-45146dd86852
multi
Daily requirement of Vitamin - A by an adult man is:
Vitamin Recommended daily requirement Vitamin A 600 mcg retinol Vitamin B1 (Thiamine) 1.4 mg Vitamin B2 (Riboflavin) 1.6 mg Vitamin B3 (Niacin) 18 mg Vitamin B5 (Pantothenic acid) 10 mg Vitamin B6 (Pyridoxine) 2 mg Vitamin B9 (Folic acid) 100 mcg Vitamin B12 (Cobalamin) 1 mcg Vitamin D 100 IU (2.5 mcg calciferol) Vitam...
3
350 mcg
100 mcg
600 mcg
2000 mcg
Social & Preventive Medicine
RDA, Nutritional Requirements
6b985d48-c7e9-4acf-8f3b-45b819116d4a
single
Battle's sign is seen ina) Fracture middle cranial fossab) Fracture base of skullc) Fracture anterior cranial fossad) All of the above
null
3
ac
a
ab
bc
Surgery
null
46c07f0d-5d5d-4718-9cf7-1663a70543b7
multi
Capgras syndrome is more common in:
null
2
Obsessive compulsive disorder
Paranoid schizophrenia
Hysteria
Schizoid personality disorder
Unknown
null
adee1baf-5855-4c5b-bf23-d2768f9164c3
single
Which of the following is true regarding the offspring of those with Huntington’s disease
As Huntington's disease is an autosomal dominant disease half of the offspring are affected . Age at which a patient becomes symptomatic is variable and has no effect on probability of transmitting the disease.
3
Half of the offspring are at risk only if the affected parent is male
Half of the offspring are at risk only if the affected parent is female
Half of the offspring are at risk for the disease
Half of the offspring are at risk if either parent is symptomatic for the disease before age of 30
Medicine
null
07d0d5d9-aca3-4d5b-9811-68a5e7aef8d6
multi
Which of the following is homogenously pink staining extracellular fibrillar protein on congo red staining?
Ans. is 'b' i.e., Amyloid * Congo red is most specific and most commonly used stain stain used for amyloidosis. Appearance of amyloid (fibrillary" 'extracellular protein) are:-a) Congo red stain on light microscopy: Pink or red color to tissue deposits.b) Congo red stain on polarized microscopy: Apple green birefringen...
2
Elastin
Amyloid
Collagen
Actin
Pathology
Histo Pathology
b5cd45ed-194b-48bc-b5fc-0641bf9d9829
single
Muscle most commonly affected by congenital absence is?
Pectoralis major and minor muscles are the most common congenitally absent muscles in humans. Ref: Ultrasound of the Musculoskeletal System, 2007, Pages 51, 285; Principles of Neurology By Allan H. Ropper, Raymond Delacy Adams, Maurice Victor, Robe H. Brown, Page 1245; Clinical Pediatric Urology By A. Barry Belman, Low...
1
Pectoralis major
Semi membranosus
Teres minor
Gluteus maximus
Surgery
null
6797f24d-5dba-4778-951d-3e78ff75edc7
single
Blood brain barrier is permeable to all except
D i.e. Protein In the brain, with the exception of choroid plexus, pituitary and the area postrema, cerebral blood vessels are unique in that the junctions between vascular endothelial cells are nearly fused (8 A pore size in comparison to 65 A of body's capillary). The paucity of pores is responsible for blood brain b...
4
Water
Gas
Lipophilic drug
Protein
Anaesthesia
null
886c87b9-5bf4-41e2-af42-b8aee00c799b
multi
Persistent diarrhoea is due to:
Persistent diarrhoea is due to EAEC (Enteroaggregative Escherichia coli). option 1 EAEC: Persistent diarrhea in developing countries. option 2 EPEC- Infantile diarrhea. Option 3 EIEC- ulceration of bowel, dysentery (resembling shigellosis). option 4 ETEC- most common cause of traveler's diarrhea.
1
EAEC
EPEC
EIEC
ETEC
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
dd13e4bc-849b-408b-bb39-5173271e9bd3
single
Which among the following is the most common site affected by psoriasis?
In psoriasis, classically patients develop sharply demarcated red plaques (raised plateaulike lesions) with silvery white scale distributed about the scalp, trunk, and limbs, with a predilection for extensor surfaces such as the elbows and knees.
2
Flexor surface
Extensor surface
Palms and soles
Oral mucosa
Skin
null
157f36d6-a55c-4d37-ac4c-f2ecc763f5fd
single
WHO regime for paucibacillary leprosy –
null
1
100 mg Dapsone daily + Rifampcin monthly (600 mg)
Dapsone daily + Rifampcin daily
Dapsone + Rifampcin + Clofazimine daily
Rifampcin + Clofazimine daily
Dental
null
c0e7e1e7-6279-4040-8396-848f54b06437
single
Colour of oxygen cylinder is –
Oxygen cylinder has black body with white shoulder.
3
Grey
Blue
Black with white shoulder
Orange
Anaesthesia
null
3f3a1918-2701-49b6-931f-aaf324d73174
single
According to the latest evidence the latent virus infection which is responsible for the pathogenesis of the achalasia is:
It is believed that cause of ganglion cell degeneration in achalasia is an autoimmune process attributable to a latent infection with human herpes simplex virus 1 combined with genetic susceptibility. Ref: Harrison, Edition-18, Page-2431.
1
Herpes simplex 1
Hepatitis C infection
Rubella
Measles
Medicine
null
257b4e93-aa6a-4a67-9047-137be86f2ca4
single
In a 27-year-old male, most common cause of a colovesical fistula would be:
Ans. (a) Crohn's diseaseRef: Sabiston 19th edition, Pages 1247, 1313* Young male most common cause of colovesical fistula: CD* Old age most common cause of colovesical fistula: Diverticular disease* Overall most common cause is diverticulitis
1
Crohn's disease
Ulcerative colitis
TB
Cancer colon
Surgery
Small & Large Intestine
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single
Chancroid may be caused by –
Besides, H. ducreyi chancroid can be caused by herpes virus hominis, corynebacterium species, staph. epidermidis, streptococci, B melaniogenicus, N. gonorrhea (rarely).
4
T. pallidium
G. donovani
Chlamydia trachomatis
Herpes hominis virus
Dental
null
810e0289-cc9a-4fc0-bbeb-235c4507e638
multi