harpreetmann/entity_extraction_ade · Datasets at Hugging Face

text stringlengths 22 455	pairs listlengths 1 24
On the 3rd day, an inferior vena cava (IVC) filter was placed with a heparin flush, after which massive IVC thrombosis developed.	[ [ "heparin", "IVC thrombosis" ] ]
We also describe a new, noninvasive method to assess magnesium-induced neuromuscular block when curariform muscle relaxant was given simultaneously.	[ [ "magnesium", "neuromuscular block" ] ]
We report the case of a patient with the acquired immunodeficiency syndrome treated with rifampicin who had a 'normal' screening test for adrenal insufficiency, yet had clinical evidence of adrenal failure.	[ [ "rifampicin", "adrenal failure" ] ]
The former patient had complained once that his visual acuity had decreased after the termination of IFN therapy, and the latter patient complained twice during IFN therapy that his visual acuity had decreased.	[ [ "IFN", "visual acuity had decreased" ] ]
We presented a patient with status asthmaticus treated with a combination of theophylline and prednisone who developed a perforated gastric ulcer.	[ [ "prednisone", "perforated gastric ulcer" ], [ "theophylline", "perforated gastric ulcer" ] ]
The azathioprine dose was low (1 mg/kg) and pancytopenia occurred after 56 days therapy.	[ [ "azathioprine", "pancytopenia" ] ]
Massive pulmonary embolism complicating streptokinase treatment for deep vein thrombosis.	[ [ "streptokinase", "Massive pulmonary embolism" ] ]
We believe that this is the first description of acute hepatitis caused by an idiosyncratic adverse reaction to gliclazide or to one of its metabolites.	[ [ "gliclazide", "acute hepatitis" ] ]
3. Thus, the decreased plasma cortisol level during alprazolam treatment of panic disorder was suggested to be caused not by symptom alleviation due to alprazolam but by alprazolam administration itself.	[ [ "alprazolam", "decreased plasma cortisol level" ] ]
Ifosfamide-associated neurotoxicity was noted within hours of drug administration and improved rapidly following hemodialysis.	[ [ "Ifosfamide", "neurotoxicity" ] ]
This case demonstrates the association of selective IgA deficiency with remission in rheumatoid arthritis induced by fenclofenac as well as aurothiomalate and sulphasalazine.	[ [ "sulphasalazine", "IgA deficiency" ], [ "aurothiomalate", "IgA deficiency" ], [ "fenclofenac", "IgA deficiency" ] ]
Nifedipine may induce, or aggravate, pre-existing, gastro-oesophageal reflux.	[ [ "Nifedipine", "gastro-oesophageal reflux" ] ]
Pulmonary edema as a delayed complication of ritodrine therapy.	[ [ "ritodrine", "Pulmonary edema" ] ]
A MEDLINE search identified all the reported cases of hypersensitivity reactions to cyclosporine.	[ [ "cyclosporine", "hypersensitivity reactions" ] ]
The authors report a case of Balint syndrome with irreversible posterior leukoencephalopathy on MRI following intrathecal methotrexate and cytarabine.	[ [ "methotrexate", "posterior leukoencephalopathy" ], [ "cytarabine", "Balint syndrome" ], [ "methotrexate", "Balint syndrome" ], [ "cytarabine", "posterior leukoencephalopathy" ] ]
Pure red cell aplasia associated with fenoprofen.	[ [ "fenoprofen", "Pure red cell aplasia" ] ]
Given that discontinuation of nitrofurantoin and introduction of methylprednisolon therapy significantly lowered liver enzyme levels, restoring most of them to normal, we concluded that this was probably the case of toxic liver damage caused by nitrofurantoin.	[ [ "nitrofurantoin", "toxic liver damage" ] ]
Vigabatrin-induced visual field defects are at present the most important safety issue in the use of the drug.	[ [ "Vigabatrin", "visual field defects" ] ]
CASE: A malignant mixed mesodermal tumor was diagnosed in a 64-year-old woman with a bicornuate uterus while she was taking raloxifene for osteoporosis prevention.	[ [ "raloxifene", "malignant mixed mesodermal tumor" ] ]
There is a dose-effect relationship between doxorubicin and the incidence of symptomatic cardiac failure.	[ [ "doxorubicin", "symptomatic cardiac failure" ] ]
Acute aluminum toxicity after continuous intravesical alum irrigation for hemorrhagic cystitis.	[ [ "alum", "aluminum toxicity" ] ]
On the other hand, aspirin may have promoted the enlargement of spontaneous hemorrhage from meningioma.	[ [ "aspirin", "enlargement of spontaneous hemorrhage" ] ]
A case of acute subdural haematoma originating spontaneously from an angiomatous meningioma in a patient receiving prophylactic aspirin therapy is presented.	[ [ "aspirin", "acute subdural haematoma" ] ]
Failure of plasmapheresis, corticosteroids and thionamides to ameliorate a case of protracted amiodarone-induced thyroiditis.	[ [ "amiodarone", "thyroiditis" ] ]
Anaphylaxis to cisplatin following nine previous uncomplicated cycles.	[ [ "cisplatin", "Anaphylaxis" ] ]
CONCLUSION: Although a definite association has not been proven, clinicians should be aware of the possibility of agranulocytosis while using quetiapine.	[ [ "quetiapine", "agranulocytosis" ] ]
Hyperkalaemia with renal tubular dysfunction by oral therapy of sulfamethoxazole-trimethoprim (co-trimoxazole) is described in 2 elderly Japanese patients with lymphoid malignancy, who developed Pneumocystis carinii pneumonia and improved.	[ [ "sulfamethoxazole-trimethoprim", "renal tubular dysfunction" ], [ "co-trimoxazole", "Hyperkalaemia" ], [ "co-trimoxazole", "renal tubular dysfunction" ], [ "sulfamethoxazole-trimethoprim", "Hyperkalaemia" ] ]
We report a case of contact dermatitis due to sodium bisulfite in Tathion eye drops.	[ [ "sodium bisulfite", "contact dermatitis" ] ]
Rifampicin-induced adrenal insufficiency in the acquired immunodeficiency syndrome: difficulties in diagnosis and treatment.	[ [ "Rifampicin", "adrenal insufficiency" ] ]
Peripheral neuropathy associated with capecitabine.	[ [ "capecitabine", "Peripheral neuropathy" ] ]
Children with acute lymphoblastic leukemia (ALL), treated with L-asparaginase are at risk for cerebral thrombosis or hemorrhage because of coagulation protein deficiencies.	[ [ "L-asparaginase", "coagulation protein deficiencies" ], [ "L-asparaginase", "hemorrhage" ], [ "L-asparaginase", "cerebral thrombosis" ] ]
Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac.	[ [ "amprenavir", "intracranial bleeding" ] ]
Uveitis associated with rifabutin therapy: a clinical alert.	[ [ "rifabutin", "Uveitis" ] ]
An asymptomatic HIV-infected woman experienced right-sided renal colicky pain during treatment with indinavir.	[ [ "indinavir", "renal colicky pain" ] ]
A 78-year-old man with a transvenous cardioverter defibrillator system developed frequent shocks during oral procainamide therapy.	[ [ "procainamide", "shocks" ] ]
Polysomnographic and pharmacokinetic findings in levodopa-induced augmentation of restless legs syndrome.	[ [ "levodopa", "restless legs syndrome" ] ]
CASE REPORT: We present a case of a 28-yr-old male who developed a severe case of nephrotic syndrome while being treated for relapsing/remitting Multiple Sclerosis (RRMS) with weekly injections of interferon beta 1a.	[ [ "interferon beta 1a", "nephrotic syndrome" ] ]
In this report we described a case of juvenile idiopathic arthritis patient who developed thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms under Etanercept treatment.	[ [ "Etanercept", "pleurisy" ], [ "Etanercept", "thymic hyperplasia" ], [ "Etanercept", "thymic enlargement" ], [ "Etanercept", "mediastinal lymphadenopathy" ] ]
A young diamond dealer developed visual impairment attributed to bilateral posterior subcapsular cataracts following only four courses of intermittent Decadron used as part of a five-drug antiemetic regimen for cisplatin-associated nausea.	[ [ "Decadron", "visual impairment" ], [ "Decadron", "bilateral posterior subcapsular cataracts" ], [ "cisplatin", "nausea" ] ]
Capecitabine was discontinued and the allergic reactions resolved after the woman took diphenhydramine for 1 week.	[ [ "Capecitabine", "allergic reactions" ] ]
We report the first case of rhabdomyolysis related to the administration of clarithromycin without concurrent use of other medications.	[ [ "clarithromycin", "rhabdomyolysis" ] ]
Dapsone syndrome in cutaneous lupus erythematosus.	[ [ "Dapsone", "Dapsone syndrome" ] ]
Widespread cutaneous vasculitis associated with diltiazem.	[ [ "diltiazem", "cutaneous vasculitis" ] ]
Severe visual loss after a single dose of vincristine in a patient with spinal cord astrocytoma.	[ [ "vincristine", "Severe visual loss" ] ]
An infant who developed pancreatitis during meglumine antimoniate treatment for visceral leishmaniasis and who was successfully treated with a combination of allopurinol and ketoconazole is reported.	[ [ "meglumine antimoniate", "pancreatitis" ] ]
We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.	[ [ "Viramune", "fulminant hepatitis" ], [ "nevirapine", "fulminant hepatitis" ] ]
CONCLUSIONS: We report the first case of gemcitabine-induced LABD.	[ [ "gemcitabine", "LABD" ] ]
This case supports the view that in gold-induced pneumonitis a prolonged treatment with corticosteroids may be necessary, as lung function continued to improve.	[ [ "gold", "pneumonitis" ] ]
Various case reports concerning dapsone-induced agranulocytosis are reviewed.	[ [ "dapsone", "agranulocytosis" ] ]
Gemcitabine therapy has been associated with radiation recall reactions when used in the treatment of carcinoma.	[ [ "Gemcitabine", "radiation recall reactions" ] ]
Due to the increasing use of TMP-SMX in children, clinicians should be aware of this potentially life-threatening, immunemediated hypersensitivity reaction.	[ [ "TMP-SMX", "immunemediated hypersensitivity reaction" ] ]
The purpose of this article is to present the first case-series of posterior reversible encephalopathy syndrome (PRES) associated with L-asparaginase treatment.	[ [ "L-asparaginase", "PRES" ], [ "L-asparaginase", "posterior reversible encephalopathy syndrome" ] ]
Three months following splenectomy, multiple abscesses occurred in the muscles of both thighs while the patient was receiving the third course of the CHOP regimen.	[ [ "CHOP", "multiple abscesses" ] ]
The neurotoxicity seen with HDARAC is dose-related and has occurred in up to 60 percent of treated patients.	[ [ "HDARAC", "neurotoxicity" ] ]
We report 3 patients with severe hepatocellular damage due to CPA therapy, 2 with fatal fulminant hepatitis.	[ [ "CPA", "fatal fulminant hepatitis" ], [ "CPA", "severe hepatocellular damage" ] ]
Pravastatin is associated with myotonia in animals.	[ [ "Pravastatin", "myotonia" ] ]
However, cyclosporine dependency is associated with the risk of nephrotoxicity.	[ [ "cyclosporine", "nephrotoxicity" ] ]
The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoproliferative diseases, but coincidence cannot be excluded.	[ [ "methotrexate", "lymphoproliferative diseases" ] ]
Eye movement disorders in bone marrow transplant patients on cyclosporin and ganciclovir.	[ [ "ganciclovir", "Eye movement disorders" ], [ "cyclosporin", "Eye movement disorders" ] ]
However, EO-induced noncardiogenic pulmonary edema has not been reported in human.	[ [ "EO", "noncardiogenic pulmonary edema" ] ]
Potential mechanisms involved in the occurrence of ischemic colitis in patients receiving tegaserod are also discussed.	[ [ "tegaserod", "ischemic colitis" ] ]
Agranulocytosis induced by vancomycin in an ESRD patient on CAPD.	[ [ "vancomycin", "Agranulocytosis" ] ]
He was started on oral lansoprazole 60 mg twice daily and, on hospital day 2, his platelet count decreased to 102 x 10(3)/mm(3); on hospital day 3, the platelet count was 36 x 10(3)/mm(3).	[ [ "lansoprazole", "platelet count decreased" ] ]
Dasatinib-induced pleural effusions: a lymphatic network disorder?	[ [ "Dasatinib", "pleural effusions" ] ]
In patients with swallowing dysfunction and pneumonia, a history of mineral oil use should be obtained and a diagnosis of ELP should be considered in the differential diagnoses if mineral oil use has occurred.	[ [ "mineral oil", "ELP" ], [ "mineral oil", "pneumonia" ], [ "mineral oil", "swallowing dysfunction" ] ]
First case of ivermectin-induced severe hepatitis.	[ [ "ivermectin", "severe hepatitis" ] ]
Many clinicians appear to be concerned about the potential hepatotoxicity of the opiate antagonist naltrexone (NTX) and this may be one reason why it is not used more widely in treating both heroin and alcohol abusers.	[ [ "naltrexone", "hepatotoxicity" ], [ "NTX", "hepatotoxicity" ] ]
Valproate-induced hyperammonemia as a cause of altered mental status.	[ [ "Valproate", "hyperammonemia" ], [ "Valproate", "altered mental status" ] ]
Immobilization, while Paget's bone disease was present, and perhaps enhanced activation of dihydrotachysterol by rifampicin, could have led to increased calcium-release into the circulation.	[ [ "dihydrotachysterol", "increased calcium-release" ] ]
A 37-year-old woman with relapsing invasive vertebral aspergillosis received intravenous VRC and developed angio-oedema 10 days after starting therapy.	[ [ "VRC", "angio-oedema" ] ]
Scrotal ulceration induced by all-trans retinoic acid in a patient with acute promyelocytic leukemia.	[ [ "retinoic acid", "Scrotal ulceration" ] ]
Amiodarone was discontinued, and thyrotoxicosis gradually abated.	[ [ "Amiodarone", "thyrotoxicosis" ] ]
Three patients who had experienced neuroleptic-induced akathisia in the past reported that the symptoms of fluoxetine-induced akathisia were identical, although somewhat milder.	[ [ "fluoxetine", "akathisia" ] ]
Anaphylactoid shock, disseminated intravascular coagulation, and anuric renal failure requiring dialysis occurred in a patient receiving zomepirac sodium for toothache.	[ [ "zomepirac", "disseminated intravascular coagulation" ], [ "zomepirac", "Anaphylactoid shock" ], [ "zomepirac", "anuric renal failure" ] ]
Hypercalcemia in an AIDS patient treated with growth hormone.	[ [ "growth hormone", "Hypercalcemia" ] ]
Pulmonary fibrosis subsequent to high doses of CCNU for chronic myeloid leukemia.	[ [ "CCNU", "Pulmonary fibrosis" ] ]
Recent reports have shown that Decadron (dexamethasone; Merck Sharp & Dohme, West Point, Pa) has a significant antiemetic effect on cisplatin-induced vomiting.	[ [ "cisplatin", "vomiting" ] ]
Phenobarbital hepatotoxicity in an 8-month-old infant.	[ [ "Phenobarbital", "hepatotoxicity" ] ]
Case report: life-threatening hypoglycaemia associated with sulfadoxine-pyrimethamine, a commonly used antimalarial drug.	[ [ "sulfadoxine-pyrimethamine", "life-threatening hypoglycaemia" ] ]
Severe corneal toxicity after topical fluoroquinolone therapy: report of two cases.	[ [ "fluoroquinolone", "Severe corneal toxicity" ] ]
Hyperammonemia has been described as a complication of valproic acid therapy but may often be overlooked as a cause of lethargy in the postictal patient who presents to the emergency department.	[ [ "valproic acid", "lethargy" ], [ "valproic acid", "Hyperammonemia" ] ]
OBJECTIVE: Clozapine causes few extrapyramidal symptoms and is recommended as a treatment drug for severe tardive dyskinesia (TD).	[ [ "Clozapine", "extrapyramidal symptoms" ] ]
In association with this tocolysis, urinary calculus of magnesium ammonium phosphate occurred at 34 weeks gestation.	[ [ "magnesium ammonium phosphate", "urinary calculus" ] ]
A 60-year-old white man with chronic bronchitis was noted to develop acute respiratory failure and metabolic acidosis four days after being started on methazolamide (Neptazane) for an ophthalmologic problem.	[ [ "methazolamide", "metabolic acidosis" ], [ "Neptazane", "acute respiratory failure" ], [ "methazolamide", "acute respiratory failure" ], [ "Neptazane", "metabolic acidosis" ] ]
RESULTS: Similar to previous findings of drug-induced vortex keratopathy, atovaquone vortex keratopathy is presumably caused by its lipophilic properties.	[ [ "atovaquone", "vortex keratopathy" ] ]
Adriamycin-induced cardiomyopathy aggravated by cis-platinum nephrotoxicity requiring dialysis.	[ [ "Adriamycin", "cardiomyopathy" ], [ "cis-platinum", "nephrotoxicity" ] ]
Nephrotic syndrome associated with lithium therapy.	[ [ "lithium", "Nephrotic syndrome" ] ]
Pellagra encephalopathy among tuberculous patients: its relation to isoniazid therapy.	[ [ "isoniazid", "Pellagra encephalopathy" ] ]
Abdominal wall ulceration and mucinosis secondary to recombinant human interferon-beta-1b.	[ [ "recombinant human interferon-beta-1b", "Abdominal wall ulceration" ], [ "recombinant human interferon-beta-1b", "mucinosis" ] ]
Severe histological osteomalacia developed in a woman with Crohn's disease 2 years after ileal resection and the start of cholestyramine therapy.	[ [ "cholestyramine", "osteomalacia" ] ]
We describe a patient with Wilson's disease who presented with neurologic disease, was treated with D-penicillamine, and suffered sudden neurologic deterioration coincident with therapy.	[ [ "D-penicillamine", "neurologic deterioration" ] ]
An immediate hemolytic reaction induced by repeated administration of oxaliplatin.	[ [ "oxaliplatin", "hemolytic reaction" ] ]
Rosaceiform eruption induced by erlotinib.	[ [ "erlotinib", "Rosaceiform eruption" ] ]
The known side effects of sibutramine, ie, hypertension and tachycardia, depend on its adrenergic and serotoninergic effects.	[ [ "sibutramine", "tachycardia" ], [ "sibutramine", "hypertension" ] ]
Spontaneous nasal septal perforation with antiangiogenic bevacizumab therapy.	[ [ "bevacizumab", "Spontaneous nasal septal perforation" ] ]
Gynaecomastia is a rarely reported adverse drug reaction due to isoniazid therapy.	[ [ "isoniazid", "Gynaecomastia" ] ]
Alopecia, nausea, and vomiting were attributed to the cyclophosphamide component of the therapy.	[ [ "cyclophosphamide", "vomiting" ], [ "cyclophosphamide", "nausea" ], [ "cyclophosphamide", "Alopecia" ] ]
METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.	[ [ "bimatoprost", "intense conjunctival hyperemia" ], [ "bimatoprost", "cystoid macula edema" ], [ "latanoprost", "cystoid macula edema" ], [ "latanoprost", "intense conjunctival hyperemia" ], [ "bimatoprost", "cystoid macular edema" ], [ "latanoprost", "cystoid macular edema" ] ]
We report five cases of restless legs syndrome (RLS) and periodic limb movements during sleep (PLMS) that were probably associated with olanzapine.	[ [ "olanzapine", "PLMS" ], [ "olanzapine", "periodic limb movements during sleep" ], [ "olanzapine", "RLS" ], [ "olanzapine", "restless legs syndrome" ] ]
A reversible toxic liver damage was observed in a non-alcoholic woman treated with disulfiram.	[ [ "disulfiram", "reversible toxic liver damage" ] ]

On the 3rd day, an inferior vena cava (IVC) filter was placed with a heparin flush, after which massive IVC thrombosis developed.

[ [ "heparin", "IVC thrombosis" ] ]

We also describe a new, noninvasive method to assess magnesium-induced neuromuscular block when curariform muscle relaxant was given simultaneously.

[ [ "magnesium", "neuromuscular block" ] ]

We report the case of a patient with the acquired immunodeficiency syndrome treated with rifampicin who had a 'normal' screening test for adrenal insufficiency, yet had clinical evidence of adrenal failure.

[ [ "rifampicin", "adrenal failure" ] ]

The former patient had complained once that his visual acuity had decreased after the termination of IFN therapy, and the latter patient complained twice during IFN therapy that his visual acuity had decreased.

[ [ "IFN", "visual acuity had decreased" ] ]

We presented a patient with status asthmaticus treated with a combination of theophylline and prednisone who developed a perforated gastric ulcer.

[ [ "prednisone", "perforated gastric ulcer" ], [ "theophylline", "perforated gastric ulcer" ] ]

The azathioprine dose was low (1 mg/kg) and pancytopenia occurred after 56 days therapy.

[ [ "azathioprine", "pancytopenia" ] ]

Massive pulmonary embolism complicating streptokinase treatment for deep vein thrombosis.

[ [ "streptokinase", "Massive pulmonary embolism" ] ]

We believe that this is the first description of acute hepatitis caused by an idiosyncratic adverse reaction to gliclazide or to one of its metabolites.

[ [ "gliclazide", "acute hepatitis" ] ]

3. Thus, the decreased plasma cortisol level during alprazolam treatment of panic disorder was suggested to be caused not by symptom alleviation due to alprazolam but by alprazolam administration itself.

[ [ "alprazolam", "decreased plasma cortisol level" ] ]

Ifosfamide-associated neurotoxicity was noted within hours of drug administration and improved rapidly following hemodialysis.

[ [ "Ifosfamide", "neurotoxicity" ] ]

This case demonstrates the association of selective IgA deficiency with remission in rheumatoid arthritis induced by fenclofenac as well as aurothiomalate and sulphasalazine.

[ [ "sulphasalazine", "IgA deficiency" ], [ "aurothiomalate", "IgA deficiency" ], [ "fenclofenac", "IgA deficiency" ] ]

Nifedipine may induce, or aggravate, pre-existing, gastro-oesophageal reflux.

[ [ "Nifedipine", "gastro-oesophageal reflux" ] ]

Pulmonary edema as a delayed complication of ritodrine therapy.

[ [ "ritodrine", "Pulmonary edema" ] ]

A MEDLINE search identified all the reported cases of hypersensitivity reactions to cyclosporine.

[ [ "cyclosporine", "hypersensitivity reactions" ] ]

The authors report a case of Balint syndrome with irreversible posterior leukoencephalopathy on MRI following intrathecal methotrexate and cytarabine.

[ [ "methotrexate", "posterior leukoencephalopathy" ], [ "cytarabine", "Balint syndrome" ], [ "methotrexate", "Balint syndrome" ], [ "cytarabine", "posterior leukoencephalopathy" ] ]

Pure red cell aplasia associated with fenoprofen.

[ [ "fenoprofen", "Pure red cell aplasia" ] ]

Given that discontinuation of nitrofurantoin and introduction of methylprednisolon therapy significantly lowered liver enzyme levels, restoring most of them to normal, we concluded that this was probably the case of toxic liver damage caused by nitrofurantoin.

[ [ "nitrofurantoin", "toxic liver damage" ] ]

Vigabatrin-induced visual field defects are at present the most important safety issue in the use of the drug.

[ [ "Vigabatrin", "visual field defects" ] ]

CASE: A malignant mixed mesodermal tumor was diagnosed in a 64-year-old woman with a bicornuate uterus while she was taking raloxifene for osteoporosis prevention.

[ [ "raloxifene", "malignant mixed mesodermal tumor" ] ]

There is a dose-effect relationship between doxorubicin and the incidence of symptomatic cardiac failure.

[ [ "doxorubicin", "symptomatic cardiac failure" ] ]

Acute aluminum toxicity after continuous intravesical alum irrigation for hemorrhagic cystitis.

[ [ "alum", "aluminum toxicity" ] ]

On the other hand, aspirin may have promoted the enlargement of spontaneous hemorrhage from meningioma.

[ [ "aspirin", "enlargement of spontaneous hemorrhage" ] ]

A case of acute subdural haematoma originating spontaneously from an angiomatous meningioma in a patient receiving prophylactic aspirin therapy is presented.

[ [ "aspirin", "acute subdural haematoma" ] ]

Failure of plasmapheresis, corticosteroids and thionamides to ameliorate a case of protracted amiodarone-induced thyroiditis.

[ [ "amiodarone", "thyroiditis" ] ]

Anaphylaxis to cisplatin following nine previous uncomplicated cycles.

[ [ "cisplatin", "Anaphylaxis" ] ]

CONCLUSION: Although a definite association has not been proven, clinicians should be aware of the possibility of agranulocytosis while using quetiapine.

[ [ "quetiapine", "agranulocytosis" ] ]

Hyperkalaemia with renal tubular dysfunction by oral therapy of sulfamethoxazole-trimethoprim (co-trimoxazole) is described in 2 elderly Japanese patients with lymphoid malignancy, who developed Pneumocystis carinii pneumonia and improved.

[ [ "sulfamethoxazole-trimethoprim", "renal tubular dysfunction" ], [ "co-trimoxazole", "Hyperkalaemia" ], [ "co-trimoxazole", "renal tubular dysfunction" ], [ "sulfamethoxazole-trimethoprim", "Hyperkalaemia" ] ]

We report a case of contact dermatitis due to sodium bisulfite in Tathion eye drops.

[ [ "sodium bisulfite", "contact dermatitis" ] ]

Rifampicin-induced adrenal insufficiency in the acquired immunodeficiency syndrome: difficulties in diagnosis and treatment.

[ [ "Rifampicin", "adrenal insufficiency" ] ]

Peripheral neuropathy associated with capecitabine.

[ [ "capecitabine", "Peripheral neuropathy" ] ]

Children with acute lymphoblastic leukemia (ALL), treated with L-asparaginase are at risk for cerebral thrombosis or hemorrhage because of coagulation protein deficiencies.

[ [ "L-asparaginase", "coagulation protein deficiencies" ], [ "L-asparaginase", "hemorrhage" ], [ "L-asparaginase", "cerebral thrombosis" ] ]

Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac.

[ [ "amprenavir", "intracranial bleeding" ] ]

Uveitis associated with rifabutin therapy: a clinical alert.

[ [ "rifabutin", "Uveitis" ] ]

An asymptomatic HIV-infected woman experienced right-sided renal colicky pain during treatment with indinavir.

[ [ "indinavir", "renal colicky pain" ] ]

A 78-year-old man with a transvenous cardioverter defibrillator system developed frequent shocks during oral procainamide therapy.

[ [ "procainamide", "shocks" ] ]

Polysomnographic and pharmacokinetic findings in levodopa-induced augmentation of restless legs syndrome.

[ [ "levodopa", "restless legs syndrome" ] ]

CASE REPORT: We present a case of a 28-yr-old male who developed a severe case of nephrotic syndrome while being treated for relapsing/remitting Multiple Sclerosis (RRMS) with weekly injections of interferon beta 1a.

[ [ "interferon beta 1a", "nephrotic syndrome" ] ]

In this report we described a case of juvenile idiopathic arthritis patient who developed thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms under Etanercept treatment.

[ [ "Etanercept", "pleurisy" ], [ "Etanercept", "thymic hyperplasia" ], [ "Etanercept", "thymic enlargement" ], [ "Etanercept", "mediastinal lymphadenopathy" ] ]

A young diamond dealer developed visual impairment attributed to bilateral posterior subcapsular cataracts following only four courses of intermittent Decadron used as part of a five-drug antiemetic regimen for cisplatin-associated nausea.

[ [ "Decadron", "visual impairment" ], [ "Decadron", "bilateral posterior subcapsular cataracts" ], [ "cisplatin", "nausea" ] ]

Capecitabine was discontinued and the allergic reactions resolved after the woman took diphenhydramine for 1 week.

[ [ "Capecitabine", "allergic reactions" ] ]

We report the first case of rhabdomyolysis related to the administration of clarithromycin without concurrent use of other medications.

[ [ "clarithromycin", "rhabdomyolysis" ] ]

Dapsone syndrome in cutaneous lupus erythematosus.

[ [ "Dapsone", "Dapsone syndrome" ] ]

Widespread cutaneous vasculitis associated with diltiazem.

[ [ "diltiazem", "cutaneous vasculitis" ] ]

Severe visual loss after a single dose of vincristine in a patient with spinal cord astrocytoma.

[ [ "vincristine", "Severe visual loss" ] ]

An infant who developed pancreatitis during meglumine antimoniate treatment for visceral leishmaniasis and who was successfully treated with a combination of allopurinol and ketoconazole is reported.

[ [ "meglumine antimoniate", "pancreatitis" ] ]

We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.

[ [ "Viramune", "fulminant hepatitis" ], [ "nevirapine", "fulminant hepatitis" ] ]

CONCLUSIONS: We report the first case of gemcitabine-induced LABD.

[ [ "gemcitabine", "LABD" ] ]

This case supports the view that in gold-induced pneumonitis a prolonged treatment with corticosteroids may be necessary, as lung function continued to improve.

[ [ "gold", "pneumonitis" ] ]

Various case reports concerning dapsone-induced agranulocytosis are reviewed.

[ [ "dapsone", "agranulocytosis" ] ]

Gemcitabine therapy has been associated with radiation recall reactions when used in the treatment of carcinoma.

[ [ "Gemcitabine", "radiation recall reactions" ] ]

Due to the increasing use of TMP-SMX in children, clinicians should be aware of this potentially life-threatening, immunemediated hypersensitivity reaction.

[ [ "TMP-SMX", "immunemediated hypersensitivity reaction" ] ]

The purpose of this article is to present the first case-series of posterior reversible encephalopathy syndrome (PRES) associated with L-asparaginase treatment.

[ [ "L-asparaginase", "PRES" ], [ "L-asparaginase", "posterior reversible encephalopathy syndrome" ] ]

Three months following splenectomy, multiple abscesses occurred in the muscles of both thighs while the patient was receiving the third course of the CHOP regimen.

[ [ "CHOP", "multiple abscesses" ] ]

The neurotoxicity seen with HDARAC is dose-related and has occurred in up to 60 percent of treated patients.

[ [ "HDARAC", "neurotoxicity" ] ]

We report 3 patients with severe hepatocellular damage due to CPA therapy, 2 with fatal fulminant hepatitis.

[ [ "CPA", "fatal fulminant hepatitis" ], [ "CPA", "severe hepatocellular damage" ] ]

Pravastatin is associated with myotonia in animals.

[ [ "Pravastatin", "myotonia" ] ]

However, cyclosporine dependency is associated with the risk of nephrotoxicity.

[ [ "cyclosporine", "nephrotoxicity" ] ]

The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoproliferative diseases, but coincidence cannot be excluded.

[ [ "methotrexate", "lymphoproliferative diseases" ] ]

Eye movement disorders in bone marrow transplant patients on cyclosporin and ganciclovir.

[ [ "ganciclovir", "Eye movement disorders" ], [ "cyclosporin", "Eye movement disorders" ] ]

However, EO-induced noncardiogenic pulmonary edema has not been reported in human.

[ [ "EO", "noncardiogenic pulmonary edema" ] ]

Potential mechanisms involved in the occurrence of ischemic colitis in patients receiving tegaserod are also discussed.

[ [ "tegaserod", "ischemic colitis" ] ]

Agranulocytosis induced by vancomycin in an ESRD patient on CAPD.

[ [ "vancomycin", "Agranulocytosis" ] ]

He was started on oral lansoprazole 60 mg twice daily and, on hospital day 2, his platelet count decreased to 102 x 10(3)/mm(3); on hospital day 3, the platelet count was 36 x 10(3)/mm(3).

[ [ "lansoprazole", "platelet count decreased" ] ]

Dasatinib-induced pleural effusions: a lymphatic network disorder?

[ [ "Dasatinib", "pleural effusions" ] ]

In patients with swallowing dysfunction and pneumonia, a history of mineral oil use should be obtained and a diagnosis of ELP should be considered in the differential diagnoses if mineral oil use has occurred.

[ [ "mineral oil", "ELP" ], [ "mineral oil", "pneumonia" ], [ "mineral oil", "swallowing dysfunction" ] ]

First case of ivermectin-induced severe hepatitis.

[ [ "ivermectin", "severe hepatitis" ] ]

Many clinicians appear to be concerned about the potential hepatotoxicity of the opiate antagonist naltrexone (NTX) and this may be one reason why it is not used more widely in treating both heroin and alcohol abusers.

[ [ "naltrexone", "hepatotoxicity" ], [ "NTX", "hepatotoxicity" ] ]

Valproate-induced hyperammonemia as a cause of altered mental status.

[ [ "Valproate", "hyperammonemia" ], [ "Valproate", "altered mental status" ] ]

Immobilization, while Paget's bone disease was present, and perhaps enhanced activation of dihydrotachysterol by rifampicin, could have led to increased calcium-release into the circulation.

[ [ "dihydrotachysterol", "increased calcium-release" ] ]

A 37-year-old woman with relapsing invasive vertebral aspergillosis received intravenous VRC and developed angio-oedema 10 days after starting therapy.

[ [ "VRC", "angio-oedema" ] ]

Scrotal ulceration induced by all-trans retinoic acid in a patient with acute promyelocytic leukemia.

[ [ "retinoic acid", "Scrotal ulceration" ] ]

Amiodarone was discontinued, and thyrotoxicosis gradually abated.

[ [ "Amiodarone", "thyrotoxicosis" ] ]

Three patients who had experienced neuroleptic-induced akathisia in the past reported that the symptoms of fluoxetine-induced akathisia were identical, although somewhat milder.

[ [ "fluoxetine", "akathisia" ] ]

Anaphylactoid shock, disseminated intravascular coagulation, and anuric renal failure requiring dialysis occurred in a patient receiving zomepirac sodium for toothache.

[ [ "zomepirac", "disseminated intravascular coagulation" ], [ "zomepirac", "Anaphylactoid shock" ], [ "zomepirac", "anuric renal failure" ] ]

Hypercalcemia in an AIDS patient treated with growth hormone.

[ [ "growth hormone", "Hypercalcemia" ] ]

Pulmonary fibrosis subsequent to high doses of CCNU for chronic myeloid leukemia.

[ [ "CCNU", "Pulmonary fibrosis" ] ]

Recent reports have shown that Decadron (dexamethasone; Merck Sharp & Dohme, West Point, Pa) has a significant antiemetic effect on cisplatin-induced vomiting.

[ [ "cisplatin", "vomiting" ] ]

Phenobarbital hepatotoxicity in an 8-month-old infant.

[ [ "Phenobarbital", "hepatotoxicity" ] ]

Case report: life-threatening hypoglycaemia associated with sulfadoxine-pyrimethamine, a commonly used antimalarial drug.

[ [ "sulfadoxine-pyrimethamine", "life-threatening hypoglycaemia" ] ]

Severe corneal toxicity after topical fluoroquinolone therapy: report of two cases.

[ [ "fluoroquinolone", "Severe corneal toxicity" ] ]

Hyperammonemia has been described as a complication of valproic acid therapy but may often be overlooked as a cause of lethargy in the postictal patient who presents to the emergency department.

[ [ "valproic acid", "lethargy" ], [ "valproic acid", "Hyperammonemia" ] ]

OBJECTIVE: Clozapine causes few extrapyramidal symptoms and is recommended as a treatment drug for severe tardive dyskinesia (TD).

[ [ "Clozapine", "extrapyramidal symptoms" ] ]

In association with this tocolysis, urinary calculus of magnesium ammonium phosphate occurred at 34 weeks gestation.

[ [ "magnesium ammonium phosphate", "urinary calculus" ] ]

A 60-year-old white man with chronic bronchitis was noted to develop acute respiratory failure and metabolic acidosis four days after being started on methazolamide (Neptazane) for an ophthalmologic problem.

[ [ "methazolamide", "metabolic acidosis" ], [ "Neptazane", "acute respiratory failure" ], [ "methazolamide", "acute respiratory failure" ], [ "Neptazane", "metabolic acidosis" ] ]

RESULTS: Similar to previous findings of drug-induced vortex keratopathy, atovaquone vortex keratopathy is presumably caused by its lipophilic properties.

[ [ "atovaquone", "vortex keratopathy" ] ]

Adriamycin-induced cardiomyopathy aggravated by cis-platinum nephrotoxicity requiring dialysis.

[ [ "Adriamycin", "cardiomyopathy" ], [ "cis-platinum", "nephrotoxicity" ] ]

Nephrotic syndrome associated with lithium therapy.

[ [ "lithium", "Nephrotic syndrome" ] ]

Pellagra encephalopathy among tuberculous patients: its relation to isoniazid therapy.

[ [ "isoniazid", "Pellagra encephalopathy" ] ]

Abdominal wall ulceration and mucinosis secondary to recombinant human interferon-beta-1b.

[ [ "recombinant human interferon-beta-1b", "Abdominal wall ulceration" ], [ "recombinant human interferon-beta-1b", "mucinosis" ] ]

Severe histological osteomalacia developed in a woman with Crohn's disease 2 years after ileal resection and the start of cholestyramine therapy.

[ [ "cholestyramine", "osteomalacia" ] ]

We describe a patient with Wilson's disease who presented with neurologic disease, was treated with D-penicillamine, and suffered sudden neurologic deterioration coincident with therapy.

[ [ "D-penicillamine", "neurologic deterioration" ] ]

An immediate hemolytic reaction induced by repeated administration of oxaliplatin.

[ [ "oxaliplatin", "hemolytic reaction" ] ]

Rosaceiform eruption induced by erlotinib.

[ [ "erlotinib", "Rosaceiform eruption" ] ]

The known side effects of sibutramine, ie, hypertension and tachycardia, depend on its adrenergic and serotoninergic effects.

[ [ "sibutramine", "tachycardia" ], [ "sibutramine", "hypertension" ] ]

Spontaneous nasal septal perforation with antiangiogenic bevacizumab therapy.

[ [ "bevacizumab", "Spontaneous nasal septal perforation" ] ]

Gynaecomastia is a rarely reported adverse drug reaction due to isoniazid therapy.

[ [ "isoniazid", "Gynaecomastia" ] ]

Alopecia, nausea, and vomiting were attributed to the cyclophosphamide component of the therapy.

[ [ "cyclophosphamide", "vomiting" ], [ "cyclophosphamide", "nausea" ], [ "cyclophosphamide", "Alopecia" ] ]

METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.

[ [ "bimatoprost", "intense conjunctival hyperemia" ], [ "bimatoprost", "cystoid macula edema" ], [ "latanoprost", "cystoid macula edema" ], [ "latanoprost", "intense conjunctival hyperemia" ], [ "bimatoprost", "cystoid macular edema" ], [ "latanoprost", "cystoid macular edema" ] ]

We report five cases of restless legs syndrome (RLS) and periodic limb movements during sleep (PLMS) that were probably associated with olanzapine.

[ [ "olanzapine", "PLMS" ], [ "olanzapine", "periodic limb movements during sleep" ], [ "olanzapine", "RLS" ], [ "olanzapine", "restless legs syndrome" ] ]

A reversible toxic liver damage was observed in a non-alcoholic woman treated with disulfiram.

[ [ "disulfiram", "reversible toxic liver damage" ] ]