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Wilson disease protein (WND), also known as ATP7B protein, is a copper-transporting P-type ATPase which is encoded by the ATP7B gene. The ATP7B protein is located in the trans-Golgi network of the liver and brain and balances the copper level in the body by excreting excess copper into bile and plasma. Genetic disorder... | Wikipedia/Wilson_disease_protein |
Polycystin-2 (PC2) is a protein that in humans is encoded by the PKD2 gene.
The gene PKD2 also known as TRPP2, encodes a member of the polycystin protein family, called TRPP, and contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-c... | Wikipedia/Polycystic_kidney_disease_2 |
Odorant-binding proteins (OBPs) are small (10 to 30 kDa) soluble proteins secreted by auxiliary cells surrounding olfactory receptor neurons, including the nasal mucus of many vertebrate species and in the sensillar lymph of chemosensory sensilla of insects. OBPs are characterized by a specific protein domain that comp... | Wikipedia/Odorant_binding_protein |
Photosynthetic reaction centre proteins are main protein components of photosynthetic reaction centres (RCs) of bacteria and plants. They are transmembrane proteins embedded in the chloroplast thylakoid or bacterial cell membrane.
Plants, algae, and cyanobacteria have one type of PRC for each of its two photosystems. N... | Wikipedia/Photosynthetic_reaction_centre_protein_family |
Calcium-binding proteins are proteins that participate in calcium cell signaling pathways by binding to Ca2+, the calcium ion that plays an important role in many cellular processes. Calcium-binding proteins have specific domains that bind to calcium and are known to be heterogeneous.
One of the functions of calcium bi... | Wikipedia/Calcium-binding_protein |
The insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1).
== Function ==
Approximately 98% of IGF-1 is always bound to one of six binding proteins (IGF-BP). IGFBP-3, the most abundant protein, accounts for 80% of all IGF binding. IGF-1 binds to IGFB... | Wikipedia/Insulin-like_growth_factor-binding_protein |
Porins are beta barrel proteins that cross a cellular membrane and act as a pore, through which molecules can diffuse. Unlike other membrane transport proteins, porins are large enough to allow passive diffusion, i.e., they act as channels that are specific to different types of molecules. They are present in the outer... | Wikipedia/Porin_(protein) |
Growth hormone-binding protein (GHBP) is a soluble carrier protein for growth hormone (GH). The full range of functions of GHBP remains to be determined. However, current research suggests that the protein is associated with regulation of the GH availability and half-life in the circulatory system, as well as modulati... | Wikipedia/Growth_hormone-binding_protein |
Retinol binding protein 4, also known as RBP4, is a transporter protein for retinol (vitamin A alcohol). RBP4 has a molecular weight of approximately 21 kDa and is encoded by the RBP4 gene in humans. It is mainly, though not exclusively, synthesized in the liver and circulates in the bloodstream as a hepatokine bound ... | Wikipedia/Retinol_binding_protein_4 |
The acyl carrier protein (ACP) is a cofactor of both fatty acid and polyketide biosynthesis machinery. It is one of the most abundant proteins in cells of E. coli. In both cases, the growing chain is bound to the ACP via a thioester derived from the distal thiol of a 4'-phosphopantetheine moiety.
== Structure ==
The ... | Wikipedia/Acyl_carrier_protein |
A tetrameric protein is a protein with a quaternary structure of four subunits (tetrameric). Homotetramers have four identical subunits (such as glutathione S-transferase), and heterotetramers are complexes of different subunits. A tetramer can be assembled as dimer of dimers with two homodimer subunits (such as sorbit... | Wikipedia/Tetrameric_protein |
Multi-antimicrobial extrusion protein (MATE) also known as multidrug and toxin extrusion or multidrug and toxic compound extrusion is a family of proteins which function as drug/sodium or proton antiporters.
== Function ==
The MATE proteins in bacteria, archaea and eukaryotes function as fundamental transporters of ... | Wikipedia/Multi-antimicrobial_extrusion_protein |
Multidrug resistance-associated protein 2 (MRP2) also called canalicular multispecific organic anion transporter 1 (cMOAT) or ATP-binding cassette sub-family C member 2 (ABCC2) is a protein that in humans is encoded by the ABCC2 gene.
== Function ==
MRP2 is a member of the superfamily of ATP-binding cassette (ABC) tr... | Wikipedia/Multidrug_resistance-associated_protein_2 |
Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene.
== Function ==
Heart-type Fatty Acid-Binding Protein (H-FABP) is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. L... | Wikipedia/Heart-type_fatty_acid_binding_protein |
The fatty-acid-binding proteins (FABPs) are a family of transport proteins for fatty acids and other lipophilic substances such as eicosanoids and retinoids. These proteins are thought to facilitate the transfer of fatty acids between extra- and intracellular membranes. Some family members are also believed to transp... | Wikipedia/Fatty_acid-binding_protein |
Major urinary proteins (Mups), also known as α2u-globulins, are a subfamily of proteins found in abundance in the urine and other secretions of many animals. Mups provide a small range of identifying information about the donor animal, when detected by the vomeronasal organ of the receiving animal. They belong to a lar... | Wikipedia/Major_urinary_proteins |
F-box proteins are proteins containing at least one F-box domain. The first identified F-box protein is one of three components of the SCF complex, which mediates ubiquitination of proteins targeted for degradation by the 26S proteasome.
== Core components ==
F-box domain is a protein structural motif of about 50 ami... | Wikipedia/F-box_protein |
Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In t... | Wikipedia/Sodium-glucose_transport_proteins |
Calmodulin-binding proteins are, as their name implies, proteins which bind calmodulin. Calmodulin can bind to a variety of proteins through a two-step binding mechanism, namely "conformational and mutually induced fit", where typically two domains of calmodulin wrap around an emerging helical calmodulin binding domain... | Wikipedia/Calmodulin-binding_proteins |
Riboflavin carrier proteins (RFCPs) together with human serum albumin transport flavin mononucleotide (FMN) in the blood circuit. RFCPs are important in pregnancy.
Studies from India have identified a riboflavin carrier protein (RCP) present in bird (e.g., chicken) eggs, which is considered to be specific for riboflavi... | Wikipedia/Riboflavin_carrier_protein |
The anion exchanger family (TC# 2.A.31, also named bicarbonate transporter family) is a member of the large APC superfamily of secondary carriers. Members of the AE family are generally responsible for the transport of anions across cellular barriers, although their functions may vary. All of them exchange bicarbonate.... | Wikipedia/Bicarbonate_transporter_protein |
aP2 (adipocyte Protein 2) is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages. aP2 is also called fatty acid binding protein 4 (FABP4). Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease and the metabolic syndrome.... | Wikipedia/Adipocyte_protein_2 |
The G protein-coupled inwardly rectifying potassium channels (GIRKs) are a family of lipid-gated inward-rectifier potassium ion channels which are activated (opened) by the signaling lipid PIP2 and a signal transduction cascade starting with ligand-stimulated G protein-coupled receptors (GPCRs). GPCRs in turn release ... | Wikipedia/G_protein-coupled_inwardly_rectifying_potassium_channel |
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to androgens and estrogens. When produced by the Sertoli cells in the seminiferous tubules of the testis, it is called androgen-binding protein (ABP).
Other steroid hormones such as progesterone, cortisol, and other ... | Wikipedia/Androgen-binding_protein |
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population, and application of this knowledge to prevent diseases.
It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by i... | Wikipedia/epidemiology |
The Journal of Clinical Epidemiology is a peer-reviewed journal of epidemiology. The journal was originally established as the Journal of Chronic Diseases in 1955 as a follow-up to Harry S. Truman's 1951 Presidential Task Force on national health concerns and the subsequently written Magnuson Report.
Under the editoria... | Wikipedia/Journal_of_Clinical_Epidemiology |
The Caerphilly Heart Disease Study, also known as the Caerphilly Prospective Study (CaPS), is an epidemiological prospective cohort, set up in 1979 in a representative population sample drawn from Caerphilly, a typical small town in South Wales, UK.
The initial aim was to examine relationships between a wide range of s... | Wikipedia/Caerphilly_Heart_Disease_Study |
Disease diffusion occurs when a disease is transmitted to a new location. It implies that a disease spreads, or pours out, from a central source. The idea of showing the spread of disease using a diffusion pattern is relatively modern, compared to earlier methods of mapping disease, which are still used today. Accord... | Wikipedia/Disease_diffusion_mapping |
Targeted immunization strategies are approaches designed to increase the immunization level of populations and decrease the chances of epidemic outbreaks. Though often in regards to use in healthcare practices and the administration of vaccines to prevent biological epidemic outbreaks, these strategies refer in general... | Wikipedia/Targeted_immunization_strategies |
Public health surveillance (also epidemiological surveillance, clinical surveillance or syndromic surveillance) is, according to the World Health Organization (WHO), "the continuous, systematic collection, analysis and interpretation of health-related data needed for the planning, implementation, and evaluation of publ... | Wikipedia/Clinical_surveillance |
Sodium citrate may refer to any of the sodium salts of citric acid (though most commonly the third):
Monosodium citrate
Disodium citrate
Trisodium citrate
The three forms of salt are collectively known by the E number E331.
== Applications ==
=== Food ===
Sodium citrates are used as acidity regulators in food and ... | Wikipedia/Sodium_citrate |
DTaP-IPV vaccine is a combination vaccine whose full generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed and inactivated poliovirus vaccine (IPV).
It is also known as DTaP/IPV, dTaP/IPV, DTPa-IPV, or DPT-IPV. It protects against the infectious diseases diphtheria, tetanus, pertussis, and pol... | Wikipedia/DTaP-IPV_vaccine |
The Oxford Vaccine Group (OVG) is a vaccine research group within the Department of Paediatrics at the University of Oxford. It was founded in 1994 by Professor E. Richard Moxon, was initially based at the John Radcliffe Hospital, and moved in 2003 to its current location in the Centre for Clinical Vaccinology and Trop... | Wikipedia/Oxford_Vaccine_Group |
The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. For its development, BioNTech collaborated with the American company Pfizer to carry out clinical trials, logistics, and manufacturing. It is authorized fo... | Wikipedia/Pfizer-BioNTech_COVID-19_vaccine |
Science Translational Medicine is an interdisciplinary biomedical journal established in October 2009 by the American Association for the Advancement of Science.
It publishes basic, biomedical, translational, and clinical research about human diseases. According to Web of Science, the journal has a 2023 impact factor o... | Wikipedia/Science_Translational_Medicine |
Circumsporozoite protein (CSP) is a secreted protein of the sporozoite stage of the malaria parasite (Plasmodium sp.) and is the antigenic target of RTS,S and other malaria vaccines. The amino-acid sequence of CSP consists of an immunodominant central repeat region flanked by conserved motifs at the N- and C- termini ... | Wikipedia/Circumsporozoite_protein |
PfSPZ Vaccine is a metabolically active non-replicating whole sporozoite (SPZ) malaria vaccine being developed by Sanaria against Plasmodium falciparum (Pf) malaria. Clinical trials have been safe, extremely well tolerated and highly efficacious. The first generation PfSPZ product is attenuated by gamma irradiation; th... | Wikipedia/PfSPZ_Vaccine |
A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which modify lipids, carbohydrates, or other molecules. Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activ... | Wikipedia/Protein_kinases |
The mainstay of malaria diagnosis has been the microscopic examination of blood, utilizing blood films. Although blood is the sample most frequently used to make a diagnosis, both saliva and urine have been investigated as alternative, less invasive specimens. More recently, modern techniques utilizing antigen tests or... | Wikipedia/Diagnosis_of_malaria |
Merozoite surface proteins are both integral and peripheral membrane proteins found on the surface of a merozoite, an early life cycle stage of a protozoan. Merozoite surface proteins, or MSPs, are important in understanding malaria, a disease caused by protozoans of the genus Plasmodium. During the asexual blood stag... | Wikipedia/Merozoite_surface_protein |
Drug nomenclature is the systematic naming of drugs, especially pharmaceutical drugs. In the majority of circumstances, drugs have 3 types of names: chemical names, the most important of which is the IUPAC name; generic or nonproprietary names, the most important of which are international nonproprietary names (INNs); ... | Wikipedia/Drug_nomenclature |
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a family of proteins present on the membrane surface of red blood cells (RBCs or erythrocytes) that are infected by the malarial parasite Plasmodium falciparum. PfEMP1 is synthesized during the parasite's blood stage (erythrocytic schizogony) inside the R... | Wikipedia/Plasmodium_falciparum_erythrocyte_membrane_protein_1 |
Mosquito control manages the population of mosquitoes to reduce their damage to human health, economies, and enjoyment. Control strategies range from habitat modification and chemical insecticides to biological agents and mechanical traps. Climate change, artificial intelligence (AI), and community participation are in... | Wikipedia/Mosquito_control |
Vaccine refrigerators are designed to store vaccines and other medical products at a stable temperature to ensure they do not degrade. In developing countries with a sunny climate, solar-powered vaccine refrigerators are common.
== Requirements for vaccine refrigeration ==
Many vaccines must be stored at low tempera... | Wikipedia/Vaccine_refrigerator |
Many vaccines require refrigeration to remain active, and the lack of infrastructure to maintain the cool chain to reliably bring vaccines into more remote areas of developing countries poses a serious challenge to national immunization programs. Portable vaccine cooler units have been proposed by several technologists... | Wikipedia/Vaccine_cooler |
Cysteine-rich secretory proteins, often abbreviated as CRISPs, are a group of glycoproteins. They are a subgroup of the CRISP, antigen 5 and Pr-1 (CAP) protein superfamily and also contain a domain related to the ShK toxins. They are substantially implicated in the functioning of the mammalian reproductive system. CRIS... | Wikipedia/Cysteine-rich_secretory_protein |
An academic clinical trial is a clinical trial not funded by pharmaceutical or biotechnology company for commercial ends but by public-good agencies (usually universities or medical trusts) to advance medicine. These trials are a valuable component of the health care system; they benefit patients and help determine th... | Wikipedia/Academic_clinical_trial |
The DPT vaccine or DTP vaccine is a class of combination vaccines to protect
against three infectious diseases in humans: diphtheria, pertussis (whooping cough), and tetanus (lockjaw). The vaccine components include diphtheria and tetanus toxoids, and either killed whole cells of the bacterium that causes pertussis or... | Wikipedia/DTaP_vaccine |
Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated poliovirus given by injection (IPV) and a weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all children be fully vaccinated against polio. The two vaccines have eliminated polio ... | Wikipedia/Inactivated_poliovirus_vaccine |
Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated poliovirus given by injection (IPV) and a weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all children be fully vaccinated against polio. The two vaccines have eliminated polio ... | Wikipedia/Inactivated_polio_vaccine |
Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication. The suboptimal antibodies can result from natural infection or from vacci... | Wikipedia/Antibody-dependent_enhancement |
The DrugBank database is a comprehensive, freely accessible, online database containing information on drugs and drug targets created and maintained by the University of Alberta and The Metabolomics Innovation Centre located in Alberta, Canada. As both a bioinformatics and a cheminformatics resource, DrugBank combines ... | Wikipedia/DrugBank |
Whole-cell vaccines are a type of vaccine that has been prepared in the laboratory from entire cells. Such vaccines simultaneously contain multiple antigens to activate the immune system. They induce antigen-specific T-cell responses.
Whole-cell vaccines have been researched in the fields of bacterial infectious diseas... | Wikipedia/Whole-cell_vaccine |
The Randomised Evaluation of COVID-19 Therapy (RECOVERY Trial) is a large-enrollment clinical trial of possible treatments for people in the United Kingdom admitted to hospital with severe COVID-19 infection. The trial was later expanded to Indonesia, Nepal and Vietnam. The trial has tested ten interventions on adults:... | Wikipedia/RECOVERY_Trial |
The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose. It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. The related terms therapeutic w... | Wikipedia/Maximum_tolerated_dose |
The Solidarity trial for treatments is a multinational Phase III-IV clinical trial organized by the World Health Organization (WHO) and partners to compare four untested treatments for hospitalized people with severe COVID-19 illness. The trial was announced 18 March 2020, and as of 6 August 2021, 12,000 patients in 30... | Wikipedia/Solidarity_trial |
An ecosystem model is an abstract, usually mathematical, representation of an ecological system (ranging in scale from an individual population, to an ecological community, or even an entire biome), which is studied to better understand the real system.
Using data gathered from the field, ecological relationships—such ... | Wikipedia/Ecological_model |
In immunology, antiserum is a blood serum containing antibodies (either monoclonal or polyclonal) that is used to spread passive immunity to many diseases via blood donation (plasmapheresis). For example, convalescent serum, or passive antibody transfusion from a previous human survivor, was the only known effective tr... | Wikipedia/Serotherapy |
COVI-VAC (codenamed CDX-005) is a COVID-19 vaccine developed by Codagenix, Inc. In December 2020, COVI-VAC started a Phase I clinical trial, involving 48 participants. The trial was scheduled to complete in June 2021, with results to be reported by May 2022. On September 29, 2021, Codagenix presented positive phase 1 d... | Wikipedia/COVI-VAC_(U.S._COVID-19_vaccine) |
The treatment and management of COVID-19 combines both supportive care, which includes treatment to relieve symptoms, fluid therapy, oxygen support as needed, and a growing list of approved medications. Highly effective vaccines have reduced mortality related to SARS-CoV-2; for those awaiting vaccination, as well as fo... | Wikipedia/Treatment_and_management_of_COVID-19 |
The AbC-19 rapid antibody test is an immunological test for COVID-19 exposure developed by the UK Rapid Test Consortium and manufactured by Abingdon Health. It uses a lateral flow test to determine whether a person has IgG antibodies to the SARS-CoV-2 virus that causes COVID-19. The test uses a single drop of blood obt... | Wikipedia/AbC-19_rapid_antibody_test |
COVID-19 Response Acceleration Task Force (Indonesian: Gugus Tugas Percepatan Penanganan COVID-19) was a task force that coordinated and oversaw the Indonesian government's efforts to accelerate the mitigation of the COVID-19 pandemic. It was established on 13 March 2020, coordinated by the Indonesian National Board fo... | Wikipedia/COVID-19_Response_Acceleration_Task_Force |
Broad-spectrum antivirals (BSAs) are a class of molecules or compounds, which inhibit the infection of multiple viruses from the same (intra-family BSAs) or different (inter-family BSAs) virus families. BSAs could be divided into experimental and investigational agents, and approved drugs. BSAs work by inhibiting viral... | Wikipedia/Broad-spectrum_antiviral_drug |
A booster dose is an extra administration of a vaccine after an earlier (primer) dose. After initial immunization, a booster provides a re-exposure to the immunizing antigen. It is intended to increase immunity against that antigen back to protective levels after memory against that antigen has declined through time. F... | Wikipedia/Booster_vaccine |
Vabiotech COVID-19 vaccine is a COVID-19 vaccine candidate developed by the Vaccine and Biological Production Company No. 1 (Vabiotech) in Vietnam.
== Clinical trials ==
=== Preclinical ===
In May 2020, Vietnam declared that their COVID-19 vaccine was developed after scientists successfully generated the novel coro... | Wikipedia/Vabiotech_COVID-19_vaccine |
Minhai COVID-19 vaccine (Chinese: 康泰民海新冠疫苗), trademarked as KCONVAC (Chinese: 可维克; pinyin: Kěwéikè), is a COVID-19 vaccine developed by Shenzhen Kangtai Biological Products Co. Ltd and its subsidiary, Beijing Minhai Biotechnology Co., Ltd.
== Clinical trials ==
In October 2020, KCONVAC started phase I clinical trials... | Wikipedia/Minhai_COVID-19_vaccine |
Noora (Persian: نورا) is a COVID-19 vaccine candidate developed by Baqiyatallah University of Medical Sciences in collaboration with Plasma Darman Sarv Sepid Co. (lit. White Cypress Plasma Treatment) in Iran. Introduced in June 2021, it was announced as having "successfully passed the first phase of its clinical trial"... | Wikipedia/Noora_(vaccine) |
Kandakadu Treatment and Rehabilitation Centre previously known as the Kandakadu Drug Rehabilitation Centre is a rehabilitation center located in the Welikanda, Polonnaruwa District, North Central Province in Sri Lanka. It is currently operated by the Bureau of the Commissioner General of Rehabilitation under the Minist... | Wikipedia/Kandakadu_Treatment_and_Rehabilitation_Centre |
V451 was a COVID-19 vaccine candidate developed by the University of Queensland and the Australian pharmaceutical company CSL Limited. The vaccine candidate used the University of Queensland's molecular clamp technology and the MF59 adjuvant.
== Description ==
V451 is a protein subunit vaccine. As part of the vaccin... | Wikipedia/V451_vaccine |
Abdala, technical name CIGB-66, is a COVID-19 vaccine developed by the Center for Genetic Engineering and Biotechnology in Cuba. This candidate, named after a patriotic drama by Cuban independence hero José Martí, is a protein subunit vaccine containing COVID-derived proteins that trigger an immune response. The full r... | Wikipedia/Abdala_(vaccine) |
The MVC COVID-19 vaccine (Chinese: 高端新冠肺炎疫苗; pinyin: Gāoduān xīnguàn fèiyán yìmiáo; Wade–Giles: Kaotuan hsinkuan feiyen imiao), designated MVC-COV1901 and also known as the Medigen COVID-19 vaccine, is a protein subunit COVID-19 vaccine developed by Medigen Vaccine Biologics Corporation in Taiwan, American company Dyna... | Wikipedia/MVC_COVID-19_vaccine |
Vaccine diplomacy, a form of medical diplomacy, is the use of vaccines to improve a country's diplomatic relationship and influence of other countries. Meanwhile, vaccine diplomacy also "means a set of diplomatic measures taken to ensure access to the best practices in the development of potential vaccines, to enhance ... | Wikipedia/Vaccine_diplomacy |
The COVID-19 Immunity Task Force (CITF) is one of the Government of Canada's early efforts to track the 2020 coronavirus pandemic. An external, dedicated secretariat was established in order to maximize the efficiency of the CITF's work.
== Purpose ==
The CITF was to use a serology "to survey representative samples o... | Wikipedia/COVID-19_Immunity_Task_Force |
The White House Coronavirus Task Force was the United States Department of State task force during the Trump administration. The goal of the Task Force was to coordinate and oversee the administration's efforts to monitor, prevent, contain, and mitigate the spread of coronavirus disease 2019 (COVID-19). Also referred t... | Wikipedia/White_House_Coronavirus_Task_Force |
ScienceUpFirst is a Canadian initiative launched to counter misinformation online, especially about COVID-19. Launched January 25, 2021, it brings together independent scientists, health care providers and science communicators.
== Goals and history ==
The initiative is the result of conversations between Senator Sta... | Wikipedia/ScienceUpFirst |
In connection with the COVID-19 pandemic, navies from several countries deployed hospital ships to combat the disease. Aside from providing health services, hospital ships would allow civilian hospitals to offload some of the patients, relieving the pressure on facilities ashore. However, this also means that each ship... | Wikipedia/Hospital_ships_designated_for_the_COVID-19_pandemic |
COVID-19 Contact-Confirming Application (COCOA) is a COVID-19 application for smartphones provided by the Ministry of Health, Labour and Welfare of Japan. The application uses Bluetooth to detect and record suspected close contacts between users. If the contact is diagnosed with COVID-19, the user will be notified. Aft... | Wikipedia/COVID-19_Contact-Confirming_Application |
The CureVac COVID-19 vaccine (abbreviated CVnCoV) was a COVID-19 vaccine candidate developed by CureVac N.V. and the Coalition for Epidemic Preparedness Innovations (CEPI). The vaccine showed inadequate results in its Phase III trials with only 47% efficacy. In October 2021 CureVac abandoned further development and pro... | Wikipedia/CureVac_COVID-19_vaccine |
The ImmunityBio COVID-19 vaccine, codenamed hAd5, is a non replicating viral vector COVID-19 vaccine developed by the United States-based pharmaceutical company ImmunityBio.
== Manufacturing ==
The BioVac Institute, a state-backed South African vaccine company, plans to use a deal it won to manufacture coronavirus va... | Wikipedia/ImmunityBio_COVID-19_vaccine |
The COVID-19 lab leak theory, or lab leak hypothesis, is the idea that SARS-CoV-2, the virus that caused the COVID-19 pandemic, came from a laboratory. This claim is highly controversial; there is a scientific consensus that the virus is not the result of genetic engineering, and most scientists believe it spilled into... | Wikipedia/COVID-19_lab_leak_theory |
A global energy crisis began in the aftermath of the COVID-19 pandemic in 2021, with much of the globe facing shortages and increased prices in oil, gas and electricity markets. The crisis was caused by a variety of economic factors, including the rapid post-pandemic economic rebound that outpaced energy supply, and es... | Wikipedia/2021–2023_global_energy_crisis |
The Daily Telegraph, known online and elsewhere as The Telegraph, is a British daily broadsheet conservative newspaper published in London by Telegraph Media Group and distributed in the United Kingdom and internationally. It was founded by Arthur B. Sleigh in 1855 as The Daily Telegraph and Courier. The Telegraph is c... | Wikipedia/The_Daily_Telegraph |
Stemirna COVID-19 vaccine is a COVID-19 vaccine candidate developed by Stemirna Therapeutics. The Stemirna COVID-19 vaccine is labeled as a mRNA vaccine which means it causes the body to make a protein specific to the vaccine which triggers a immune response from the body. Stemirna first started the production of vacci... | Wikipedia/Stemirna_COVID-19_vaccine |
The Sinopharm WIBP COVID-19 vaccine, also known as WIBP-CorV, is one of two inactivated virus COVID-19 vaccines developed by Sinopharm. Peer-reviewed results show that the vaccine is 72.8% effective against symptomatic cases and 100% against severe cases (26 cases in vaccinated group vs. 95 cases in placebo group). The... | Wikipedia/Sinopharm_WIBP_COVID-19_vaccine |
Media coverage of the COVID-19 pandemic includes reporting on the deaths of anti-vaccine advocates from COVID-19 as a phenomenon occurring during the COVID-19 pandemic. The media also reported on various websites documenting such deaths, with some outlets questioning whether this practice was overly unsympathetic. Repo... | Wikipedia/Deaths_of_anti-vaccine_advocates_from_COVID-19 |
Inovio COVID-19 vaccine is a COVID-19 vaccine candidate developed by Inovio Pharmaceuticals.
== History ==
In February 2020 after receiving details of the genetic sequence of the coronavirus, Inovio announced that it had produced a preclinical DNA-based vaccine as a potential therapy for COVID-19. Inovio is in compet... | Wikipedia/Inovio_COVID-19_vaccine |
The Community Activities Restrictions Enforcement or CARE (Indonesian: Pemberlakuan Pembatasan Kegiatan Masyarakat, commonly referred to as the PPKM) was a cordon sanitaire policy of the Indonesian government since early 2021 to deal with the COVID-19 pandemic. Prior to the implementation of CARE, the government had im... | Wikipedia/Community_Activities_Restrictions_Enforcement |
The Vaccine Taskforce in the United Kingdom of Great Britain and Northern Ireland was set up in April 2020 by the Second Johnson ministry, in collaboration with Chief Scientific Advisor Patrick Vallance and Chief Medical Officer Professor Chris Whitty, in order to facilitate the path towards the introduction of a COVID... | Wikipedia/Vaccine_Taskforce |
COVID-19 drug development is the research process to develop preventative therapeutic prescription drugs that would alleviate the severity of coronavirus disease 2019 (COVID-19). From early 2020 through 2021, several hundred drug companies, biotechnology firms, university research groups, and health organizations were ... | Wikipedia/COVID-19_drug_development |
AWcorna, originally termed ARCoV and also known as the Walvax COVID-19 vaccine, is an mRNA COVID-19 vaccine developed by Walvax Biotechnology, Suzhou Abogen Biosciences, and the PLA Academy of Military Science. In contrast to other mRNA COVID-19 vaccines, such as those by Pfizer-BioNTech and Moderna, this vaccine prima... | Wikipedia/Walvax_COVID-19_vaccine |
A cancer vaccine, or oncovaccine, is a vaccine that either treats existing cancer or prevents development of cancer. Vaccines that treat existing cancer are known as therapeutic cancer vaccines or tumor antigen vaccines. Some of the vaccines are "autologous", being prepared from samples taken from the patient, and are ... | Wikipedia/Tumor_antigen_vaccine |
The Inter-Agency Task Force for the Management of Emerging Infectious Diseases (IATF-EID) is an inactive task force organized by the executive of the government of the Philippines to respond to affairs concerning emerging infectious diseases in the country.
== History ==
The IATF-EID was created through Executive Ord... | Wikipedia/Inter-Agency_Task_Force_for_the_Management_of_Emerging_Infectious_Diseases |
A vaccine passport or proof of vaccination is an immunity passport employed as a credential in countries and jurisdictions as part of efforts to control the COVID-19 pandemic via vaccination. A vaccine passport is typically issued by a government or health authority, and usually consists of a digital or printed record.... | Wikipedia/Vaccine_passports_during_the_COVID-19_pandemic |
The PANORAMIC trial (short for Platform Adaptive Trial of Novel Antivirals for Early Treatment of COVID-19 in the Community) is a clinical trial in the United Kingdom testing the effectiveness of new antiviral drugs at the early stages of COVID-19 infections. The study aims to find out if antivirals can prevent death a... | Wikipedia/PANORAMIC_trial |
COVID-19 vaccine clinical research uses clinical research to establish the characteristics of COVID-19 vaccines. These characteristics include efficacy, effectiveness, and safety. As of November 2022, 40 vaccines are authorized by at least one national regulatory authority for public use:
one DNA vaccine: ZyCoV-D
four... | Wikipedia/COVID-19_vaccine_clinical_research |
The Sanofi–Translate Bio COVID-19 vaccine, also known as MRT5500 or VAW00001, was a COVID-19 vaccine candidate developed by Sanofi Pasteur and Translate Bio. The development was stopped in September 2021.
== History ==
In June 2020, Sanofi, after lagging behind its competitors, "accelerated" the development of the va... | Wikipedia/Sanofi–Translate_Bio_COVID-19_vaccine |
The Moderna COVID‑19 vaccine, sold under the brand name Spikevax, is a COVID-19 vaccine developed by the American company Moderna, the United States National Institute of Allergy and Infectious Diseases (NIAID), and the Biomedical Advanced Research and Development Authority (BARDA). Depending on the jurisdiction, it is... | Wikipedia/Moderna_vaccine |
Vaccine Maitri ("Vaccine Friendship") is a humanitarian initiative undertaken by the Indian government to provide COVID-19 vaccines to countries around the world. The government started providing vaccines from 20 January 2021. As of 21 February 2022, India had delivered around 16.29 crore (162.9 million) doses of vacci... | Wikipedia/Vaccine_Maitri |
As of 12 August 2024, 13.53 billion COVID-19 vaccine doses have been administered worldwide, with 70.6 percent of the global population having received at least one dose. While 4.19 million vaccines were then being administered daily, only 22.3 percent of people in low-income countries had received at least a first va... | Wikipedia/Deployment_of_COVID-19_vaccines |
The dendritic cell-based cancer vaccine is an innovation in therapeutic strategy for cancer patients.
Dendritic cells (DCs) are antigen presenting cells for the induction of antigen specific T cell response. DC-based immunotherapy is safe and can promote antitumor immune responses and prolonged survival of cancer patie... | Wikipedia/Dendritic_cell-based_cancer_vaccine |
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