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A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology). Usually this common ancestry is inferred from structural alignment and mechanistic similarity, even if no sequence similarity is evident. Sequence homology can then be deduced even if not apparent... | Wikipedia/Protein_superfamilies |
The Enzyme Function Initiative (EFI) is a large-scale collaborative project aiming to develop and disseminate a robust strategy to determine enzyme function through an integrated sequence–structure-based approach. The project was funded in May 2010 by the National Institute of General Medical Sciences as a Glue Grant ... | Wikipedia/Enzyme_Function_Initiative |
In molecular biology, an intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure, typically in the absence of its macromolecular interaction partners, such as other proteins or RNA. IDPs range from fully unstructured to partially structured and include random coil, ... | Wikipedia/Intrinsically_disordered_proteins |
The Worldwide Protein Data Bank (wwPDB) is an organization that maintains the archive of macromolecular structure. Its mission is to maintain a single Protein Data Bank Archive of macromolecular structural data that is freely and publicly available to the global community.
The organization has five members:
Research... | Wikipedia/Worldwide_Protein_Data_Bank |
In biology, a protein structure database is a database that is modeled around the various experimentally determined protein structures. The aim of most protein structure databases is to organize and annotate the protein structures, providing the biological community access to the experimental data in a useful way. Dat... | Wikipedia/Protein_structure_database |
The Zebrafish Information Network (ZFIN) is an online biological database of information about the zebrafish (Danio rerio). The zebrafish is a widely used model organism for genetic, genomic, and developmental studies, and ZFIN provides an integrated interface for querying and displaying the large volume of data genera... | Wikipedia/Zebrafish_Information_Network |
Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the conference is on the development and application of advanced computational met... | Wikipedia/Intelligent_Systems_for_Molecular_Biology |
The Protein Information Resource (PIR), located at Georgetown University Medical Center, is an integrated public bioinformatics resource to support genomic and proteomic research, and scientific studies. It contains protein sequences databases
== History ==
PIR was established in 1984 by the National Biomedical Rese... | Wikipedia/Protein_Information_Resource |
The Protein Data Bank (PDB) file format is a textual file format describing the three-dimensional structures of molecules held in the Protein Data Bank, now succeeded by the mmCIF format. The PDB format accordingly provides for description and annotation of protein and nucleic acid structures including atomic coordinat... | Wikipedia/Protein_Data_Bank_(file_format) |
Before the emergence of electron microscopy in the 1950s, scientists did not know the structure of a cell membrane or what its components were; biologists and other researchers used indirect evidence to identify membranes before they could actually be visualized. Specifically, it was through the models of Overton, Lan... | Wikipedia/Membrane_models |
In chemistry, a solution is defined by IUPAC as "A liquid or solid phase containing more than one substance, when for convenience one (or more) substance, which is called the solvent, is treated differently from the other substances, which are called solutes. When, as is often but not necessarily the case, the sum of t... | Wikipedia/Dilute_solution |
The Protein Data Bank (PDB) is a database for the three-dimensional structural data of large biological molecules such as proteins and nucleic acids, which is overseen by the Worldwide Protein Data Bank (wwPDB). This structural data is obtained and deposited by biologists and biochemists worldwide through the use of ex... | Wikipedia/Protein_data_bank |
Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly inherited. It typically presents as a triad of progressive psychiatric, cognitive, and motor symptoms. The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities, which p... | Wikipedia/Huntington's_disease |
Protein disulfide isomerase (EC 5.3.4.1), or PDI, is an enzyme in the endoplasmic reticulum (ER) in eukaryotes and the periplasm of bacteria that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. This allows proteins to quickly find the correct arrangement ... | Wikipedia/Protein_disulfide_isomerase |
Medical model is the term coined by psychiatrist R. D. Laing in his The Politics of the Family and Other Essays (1971), for the "set of procedures in which all doctors are trained". It includes complaint, history, physical examination, ancillary tests if needed, diagnosis, treatment, and prognosis with and without trea... | Wikipedia/Disease_model |
In molecular biology, protein aggregation is a phenomenon in which intrinsically-disordered or mis-folded proteins aggregate (i.e., accumulate and clump together) either intra- or extracellularly. Protein aggregates have been implicated in a wide variety of diseases known as amyloidoses, including ALS, Alzheimer's, Pa... | Wikipedia/Protein_aggregation |
A protein contact map represents the distance between all possible amino acid residue pairs of a three-dimensional protein structure using a binary two-dimensional matrix. For two residues
i
{\displaystyle i}
and
j
{\displaystyle j}
... | Wikipedia/Protein_contact_map |
Nuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins, and also nucleic acids, and their complexes. The field was pioneered by Richard R. Ernst and Kurt W... | Wikipedia/Protein_NMR |
In molecular biology, molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a number of classes of molecular chaperones, all of which function to assist large proteins in proper protein folding during or after synthesis, an... | Wikipedia/Chaperone_(protein) |
In structural biology, a protein subunit is a polypeptide chain or single protein molecule that assembles (or "coassembles") with others to form a protein complex.
Large assemblies of proteins such as viruses often use a small number of types of protein subunits as building blocks.
A subunit is often named with a Greek... | Wikipedia/Protein_subunit |
Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation to heat shock, but are now known to also be expressed during other stresses including exposure to cold, UV light and during wound healing or tissue remodeling. Man... | Wikipedia/Heat_shock_protein |
Fenvalerate is a synthetic pyrethroid insecticide. It is a mixture of four optical isomers which have different insecticidal activities. The 2-S alpha (or SS) configuration, known as esfenvalerate, is the most insecticidally active isomer. Fenvalerate consists of about 23% of this isomer.
Fenvalerate is an insecticid... | Wikipedia/Fenvalerate |
Pest Control is an English hardcore punk band from Leeds, West Yorkshire. They have released one studio album, in addition to their 2020 demo. A 2023 article by Metal Hammer writer Dom Lawson called the band "the single most exciting band in the UK right now".
== History ==
Leah Massey-Hay, Joseph Kerry and Ben Jones... | Wikipedia/Pest_Control_(band) |
Hunting strategy or hunting method is any specific techniques or tactics that are used to target, pursue, and hunt an animal. The term mostly applies to humans catching and killing wild animals, but can also be used in ethology and nature documentaries to describe predation strategies adopted by carnivores.
The hunting... | Wikipedia/Hunting_strategy |
Mechanical pest control is the management and control of pests using physical means such as fences, barriers or electronic wires. It includes also weeding and change of temperature to control pests. Many farmers at the moment are trying to find sustainable ways to remove pests without harming the ecosystem.
== Method... | Wikipedia/Mechanical_pest_control |
Plant disease resistance protects plants from pathogens in two ways: by pre-formed structures and chemicals, and by infection-induced responses of the immune system. Relative to a susceptible plant, disease resistance is the reduction of pathogen growth on or in the plant (and hence a reduction of disease), while the t... | Wikipedia/Plant_disease_resistance |
Physical pest control is a method of getting rid of insects and small rodents by killing, removing, or setting up barriers that will prevent further destruction of one's plants. These methods are used primarily for crop growing, but some methods can be applied to homes as well.
== Methods ==
=== Barriers ===
Row c... | Wikipedia/Physical_pest_control |
Phorate is an organophosphate used as an insecticide and acaricide.
== Overview ==
At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target o... | Wikipedia/Phorate |
Pest Control is an exclusive to audio Doctor Who story, produced as part of BBC Books' New Series Adventures line, and the first entry in the series to be produced. Written by author Peter Anghelides and read by series star David Tennant, it is also the first non-televised Doctor Who adventure to feature the companion ... | Wikipedia/Pest_Control_(Doctor_Who) |
A zoonosis ( ; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a virus, bacterium, parasite, fungi, or prion) that can jump from a non-human vertebrate to a human. When humans infect non-humans, it is called reverse zoonosis or anthroponosis.
Ma... | Wikipedia/Zoonotic_disease |
People for the Ethical Treatment of Animals (PETA; PEE-tə) is an American animal rights nonprofit organization based in Norfolk, Virginia, and led by Ingrid Newkirk, its international president.
Founded in March 1980 by Newkirk and animal rights activist Alex Pacheco, the organization first gained attention in the sum... | Wikipedia/People_for_the_Ethical_Treatment_of_Animals |
Biological control or biocontrol is a method of controlling pests, whether pest animals such as insects and mites, weeds, or pathogens affecting animals or plants by using other organisms. It relies on predation, parasitism, herbivory, or other natural mechanisms, but typically also involves an active human management ... | Wikipedia/Biological_pest_control |
Electronic pest control is the name given to any of several types of electrically powered devices designed to repel or eliminate pests, usually rodents or insects. Since these devices are not regulated under the Federal Insecticide, Fungicide, and Rodenticide Act in the United States, the EPA does not require the same ... | Wikipedia/Electronic_pest_control |
A field trial is a competitive event for gun dogs. Field trials are conducted for pointing dogs and setters, retrievers and spaniels, with each assessing the different types various working traits. In the United States, field trials are also conducted for basset hounds, beagles, and dachshunds.
== Pointer and setter ... | Wikipedia/Field_trial |
Integrated pest management (IPM), also known as integrated pest control (IPC) integrates both chemical and non-chemical practices for economic control of pests. The UN's Food and Agriculture Organization defines IPM as "the careful consideration of all available pest control techniques and subsequent integration of app... | Wikipedia/Integrated_pest_management |
The drugstore beetle (Stegobium paniceum), also known as the bread beetle, biscuit beetle, and misnamed as the biscuit weevil (despite not being a weevil), is a small brown beetle that infests a wide variety of dried plant products, where it is among the most common non-weevils. It is the only living member of the genu... | Wikipedia/Drugstore_beetle |
Population control is the practice of artificially maintaining the size of any population. It simply refers to the act of limiting the size of an animal population so that it remains manageable, as opposed to the act of protecting a species from excessive rates of extinction, which is referred to as conservation biolo... | Wikipedia/Population_control |
A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphorylation is one of the most common forms of reversible protein posttranslational modification (PTM), with up to 30% of all proteins being phosphorylated at any... | Wikipedia/Protein_phosphatase |
Inborn errors of carbohydrate metabolism are inborn errors of metabolism that affect the catabolism and anabolism of carbohydrates.
An example is lactose intolerance.
Carbohydrates account for a major portion of the human diet. These carbohydrates are composed of three principal monosaccharides: glucose, fructose and ... | Wikipedia/Inborn_errors_of_carbohydrate_metabolism |
A glycogen storage disease (GSD, also glycogenosis and dextrinosis) is a metabolic disorder caused by a deficiency of an enzyme or transport protein affecting glycogen synthesis, glycogen breakdown, or glucose breakdown, typically in muscles and/or liver cells.
GSD has two classes of cause: genetic and environmental. G... | Wikipedia/Glycogen_storage_disease |
A nanoparticle–biomolecule conjugate is a nanoparticle with biomolecules attached to its surface. Nanoparticles are minuscule particles, typically measured in nanometers (nm), that are used in nanobiotechnology to explore the functions of biomolecules. Properties of the ultrafine particles are characterized by the com... | Wikipedia/Nanoparticle–biomolecule_conjugate |
A neutralizing antibody (NAb) is an antibody that defends a cell from a pathogen or infectious particle by neutralizing any effect it has biologically. Neutralization renders the particle no longer infectious or pathogenic.
Neutralizing antibodies are part of the humoral response of the adaptive immune system against ... | Wikipedia/Broadly_neutralizing_antibody |
Strategies for engineered negligible senescence (SENS) is a range of proposed regenerative medical therapies, either planned or currently in development, for the periodic repair of all age-related damage to human tissue. These therapies have the ultimate aim of maintaining a state of negligible senescence in patients a... | Wikipedia/Strategies_for_engineered_negligible_senescence |
Precision BioSciences, Inc. is a publicly traded American clinical stage gene editing company headquartered in Durham, North Carolina. Founded in 2006, Precision is focused on developing both in vivo and ex vivo gene editing therapies using its proprietary "ARCUS" genome editing platform.
== History ==
Derek Jantz an... | Wikipedia/Precision_Biosciences |
Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279). PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell surface receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and... | Wikipedia/Programmed_cell_death_protein_1 |
Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly insert genetic material into a host genome, genome editing targets the insertions... | Wikipedia/Human_gene_editing_therapy |
The retina (from Latin rete 'net'; pl. retinae or retinas) is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerv... | Wikipedia/Retinal_disease |
The retina (from Latin rete 'net'; pl. retinae or retinas) is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerv... | Wikipedia/Retinal_diseases |
Deoxyribonucleic acid ( ; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic aci... | Wikipedia/Naked_DNA |
The Collingridge dilemma is a methodological quandary in which efforts to influence or control the further development of technology face a double-bind problem:
An information problem: impacts cannot be easily predicted until the technology is extensively developed and widely used.
A power problem: control or change i... | Wikipedia/Collingridge_dilemma |
Differential technological development is a strategy of technology governance aiming to decrease risks from emerging technologies by influencing the sequence in which they are developed. Using this strategy, societies would strive to delay the development of harmful technologies and their applications while acceleratin... | Wikipedia/Differential_technological_development |
Apolipoprotein E (Apo-E) is a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in Alzheimer's disease and cardiovascular diseases. It is encoded in humans by the gene APOE.
Apo-E belongs to a family of fat-binding proteins called apolipoproteins. In the circulation, it is prese... | Wikipedia/Apolipoprotein_E |
Peripheral artery disease (PAD) is a vascular disorder that causes abnormal narrowing of arteries other than those that supply the heart or brain. PAD can happen in any blood vessel, but it is more common in the legs than the arms.
When narrowing occurs in the heart, it is called coronary artery disease (CAD), and in t... | Wikipedia/Peripheral_artery_disease |
Gene therapy is being studied for some forms of epilepsy. It relies on viral or non-viral vectors to deliver DNA or RNA to target brain areas where seizures arise, in order to prevent the development of epilepsy or to reduce the frequency and/or severity of seizures. Gene therapy has delivered promising results in earl... | Wikipedia/Gene_therapy_for_epilepsy |
The United States Food and Drug Administration (FDA) initiated the FDA Accelerated Approval Program in 1992 to allow faster approval of drugs for serious conditions that fill an unmet medical need. The faster approval relies on use of surrogate endpoints. Drug approval typically requires clinical trials with endpoints ... | Wikipedia/Accelerated_approval_(FDA) |
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. It is the most common of the cardiovascular diseases. CA... | Wikipedia/Coronary_artery_disease |
The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment. For drug development, the clinical phases start with testing for drug safety in a few human subjects, then expand to ... | Wikipedia/Phase_I_clinical_trial |
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilica... | Wikipedia/Stem-cell_therapy |
Lipoprotein lipase deficiency is a genetic disorder in which a person has a defective gene for lipoprotein lipase, which leads to very high triglycerides, which in turn causes stomach pain and deposits of fat under the skin, and which can lead to problems with the pancreas and liver, which in turn can lead to diabete... | Wikipedia/Lipoprotein_lipase_deficiency |
Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density lipoproteins (VLDL) or chylomicrons and exchanges them for cholestery... | Wikipedia/Cholesteryl_ester_transfer_protein |
Robot-assisted surgery or robotic surgery are any types of surgical procedures that are performed using robotic systems. Robotically assisted surgery was developed to try to overcome the limitations of pre-existing minimally-invasive surgical procedures and to enhance the capabilities of surgeons performing open surger... | Wikipedia/Robot-assisted_surgery |
Retinal gene therapy holds a promise in treating different forms of non-inherited and inherited blindness.
In 2008, three independent research groups reported that patients with the rare genetic retinal disease Leber's congenital amaurosis had been successfully treated using gene therapy with adeno-associated virus (AA... | Wikipedia/Gene_therapy_of_the_human_retina |
An aging-associated disease (commonly termed age-related disease, ARD) is a disease that is most often seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself because all adult animals age (with rare exceptions) but not all... | Wikipedia/Aging-associated_diseases |
Human HGF plasmid DNA therapy of cardiomyocytes is being examined as a potential treatment for coronary artery disease (a major cause of myocardial infarction (MI)), as well as treatment for the damage that occurs to the heart after MI. After MI, the myocardium suffers from reperfusion injury which leads to death of c... | Wikipedia/Human_HGF_plasmid_DNA_therapy |
Technology in science fiction is a crucial aspect of the genre.
As science fiction emerged during the era of Industrial Revolution, the increased presence of machines in everyday life and their role in shaping of the society was a major influence on the genre. It appeared as a major element of the Proto SF, represent... | Wikipedia/Technology_in_science_fiction |
Dow AgroSciences LLC was a wholly owned subsidiary of the Dow Chemical Company specializing in not only agricultural chemicals such as pesticides, but also seeds and biotechnology solutions. The company was based in Indianapolis, Indiana, in the United States. On 31 January 2006, Dow AgroSciences announced that it ha... | Wikipedia/Dow_AgroSciences |
Neurological disorders represent a complex array of medical conditions that fundamentally disrupt the functioning of the nervous system. These disorders affect the brain, spinal cord, and nerve networks, presenting unique diagnosis, treatment, and patient care challenges. At their core, they represent disruptions to th... | Wikipedia/Neurological_disease |
Chronic granulomatous disease (CGD), also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome, is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defecti... | Wikipedia/Chronic_granulomatous_disease |
Breakthrough therapy is a United States Food and Drug Administration designation that expedites drug development that was created by Congress under Section 902 of the 9 July 2012 Food and Drug Administration Safety and Innovation Act. The FDA's "breakthrough therapy" designation is not intended to imply that a drug is ... | Wikipedia/Breakthrough_therapy |
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular he... | Wikipedia/Heart_disease |
Ablation (Latin: ablatio – removal) is the removal or destruction of something from an object by vaporization, chipping, erosive processes, or by other means. Examples of ablative materials are described below, including spacecraft material for ascent and atmospheric reentry, ice and snow in glaciology, biological tis... | Wikipedia/Ablation_therapy |
Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time.
In neurodegenerative diseases, cells of the central nervous system stop working or die via neurodegeneration. An example of this is Alzheimer's disea... | Wikipedia/Degenerative_disease |
BASF Plant Science is a subsidiary of BASF in which all plant biotechnology activities are consolidated. The company was founded in 1998 and employs approximately 700 people at 6 different locations worldwide. The headquarters of BASF Plant Science is located in Research Triangle Park (North Carolina, US) and has resea... | Wikipedia/BASF_Plant_Science |
A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosome abnormality. Although polygenic disorders are the most common, the term is mostly used when discussing disorders with a s... | Wikipedia/Hereditary_diseases |
Tay–Sachs disease is an inherited lysosomal storage disease that results in the destruction of nerve cells in the brain and spinal cord. The most common form is infantile Tay–Sachs disease, which becomes apparent around the age of three to six months of age, with the infant losing the ability to turn over, sit, or craw... | Wikipedia/Tay–Sachs_disease |
Hematology (spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the production of blood and its components, such as blood cells, hemoglobin, blood proteins, b... | Wikipedia/Blood_disease |
Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editi... | Wikipedia/Jennifer_Doudna |
Lipoprotein lipase (LPL) (EC 3.1.1.34, systematic name triacylglycerol acylhydrolase (lipoprotein-dependent)) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found i... | Wikipedia/Lipoprotein_lipase |
Gene therapy for color blindness is an experimental gene therapy of the human retina aiming to grant typical trichromatic color vision to individuals with congenital color blindness by introducing typical alleles for opsin genes. Animal testing for gene therapy began in 2007 with a 2009 breakthrough in squirrel monkeys... | Wikipedia/Gene_therapy_for_color_blindness |
Gene therapy in Parkinson's disease consists of the creation of new cells that produce a specific neurotransmitter (dopamine), protect the neural system, or the modification of genes that are related to the disease. Then these cells are transplanted to a patient with the disease. There are different kinds of treatments... | Wikipedia/Gene_therapy_in_Parkinson's_disease |
A protein corona is a dynamic coating of biomolecules, usually proteins, around the surface of a nanoparticle that forms spontaneously in colloidal nanomaterials upon exposure to biological mediums. Protein coronas can form in many different patterns depending on their size, shape, composition, charge, and surface func... | Wikipedia/Protein_corona |
The University of Tennessee Health Science Center (UTHSC) is a public medical school in Memphis, Tennessee. It includes the Colleges of Health Professions, Dentistry, Graduate Health Sciences, Medicine, Nursing, and Pharmacy. Since 1911, the University of Tennessee Health Science Center has educated nearly 57,000 healt... | Wikipedia/University_of_Tennessee_Health_Science_Center |
Gene therapy for osteoarthritis is the application of gene therapy to treat osteoarthritis (OA). Unlike pharmacological treatments which are administered locally or systemically as a series of interventions, gene therapy aims to establish sustained therapeutic effect after a single, local injection.
The main risk facto... | Wikipedia/Gene_therapy_for_osteoarthritis |
Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
... | Wikipedia/Vectors_in_Gene_Therapy |
A designer baby is an embryo or fetus whose genetic makeup has been intentionally selected or altered, often to exclude a particular gene or to remove genes associated with disease, to achieve desired traits. This process usually involves preimplantation genetic diagnosis (PGD), which analyzes multiple human embryos to... | Wikipedia/Designer_baby |
Lentiviral vectors in gene therapy is a method by which genes can be inserted, modified, or deleted in organisms using lentiviruses.
Lentiviruses are a family of viruses that are responsible for diseases like AIDS, which infect by inserting DNA into their host cells' genome. Many such viruses have been the basis of res... | Wikipedia/Lentiviral_vector_in_gene_therapy |
Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
... | Wikipedia/Vectors_in_gene_therapy |
Rab escort protein 1 (REP1) also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene.
== Function ==
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases a... | Wikipedia/Rab_escort_protein |
A subclinical infection—sometimes called a preinfection or inapparent infection—is an infection by a pathogen that causes few or no signs or symptoms of infection in the host. Subclinical infections can occur in both humans and animals. Depending on the pathogen, which can be a virus or intestinal parasite, the host ma... | Wikipedia/Subclinical_infection |
Diseases of poverty, also known as poverty-related diseases (PRDs), are diseases that are more prevalent in low-income populations. They include infectious diseases, as well as diseases related to malnutrition and poor health behaviour. Poverty is one of the major social determinants of health. The World Health Report ... | Wikipedia/Diseases_of_poverty |
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency under the Department of Health and Human Services (HHS), and is headquartered in Atlanta, Georgia. The CDC's current nominee for director is Susan Monarez. She became acti... | Wikipedia/Centers_for_Disease_Control |
Unnecessary health care (overutilization, overuse, or overtreatment) is health care provided with a higher volume or cost than is appropriate.
In the United States, where health care costs are the highest as a percentage of GDP, overuse was the predominant factor in its expense, accounting for about a third of its heal... | Wikipedia/Overtreatment |
An idiopathic disease is any disease with an unknown cause or mechanism of apparent spontaneous origin.
For some medical conditions, one or more causes are somewhat understood, but in a certain percentage of people with the condition, the cause may not be readily apparent or characterized. In these cases, the origin ... | Wikipedia/Cryptogenic_disease |
Female genital disease is a disorder of the structure or function of the female reproductive system that has a known cause and a distinctive group of symptoms, signs, or anatomical changes. The female reproductive system consists of the ovaries, fallopian tubes, uterus, vagina, and vulva. Female genital diseases can be... | Wikipedia/Female_genital_disease |
A rare disease is any disease that affects a small percentage of the population. In some parts of the world, the term orphan disease describes a rare disease whose rarity results in little or no funding or research for treatments, without financial incentives from governments or other agencies. Orphan drugs are medicat... | Wikipedia/Rare_disease |
A non-communicable disease (NCD) is a disease that is not transmissible directly from one person to another. NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others. NCDs may be ch... | Wikipedia/Non-communicable_disease |
A chronic condition (also known as chronic disease or chronic illness) is a health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time. The term chronic is often applied when the course of the disease lasts for more than three months.
Common chronic disease... | Wikipedia/Chronic_disease |
A disease is an abnormal condition that affects the body of an organism.
Disease or The Disease may also refer to:
Disease (Beartooth album) or the title song, 2018
Disease (G.G.F.H. album) or the title song, 1993
The Disease EP or the title song, by the Eyes of a Traitor, 2011
"Disease" (Matchbox Twenty song), 2002
"... | Wikipedia/Disease_(disambiguation) |
A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosome abnormality. Although polygenic disorders are the most common, the term is mostly used when discussing disorders with a s... | Wikipedia/Genetic_disease |
In epidemiology, environmental diseases are diseases that can be directly attributed to environmental factors (as distinct from genetic factors or infection). Apart from the true monogenic genetic disorders, which are rare, environment is a major determinant of the development of disease. Diet, exposure to toxins, path... | Wikipedia/Environmental_disease |
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