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### Question: Should preoperative chest computed tomography be performed in all patients with colorectal cancer? ### Context: A review was conducted of all preoperative CCTs and X-rays performed in patients submitted to elective resection of CRC at our institution between 2005 and 2012. All scans were revised by an ind... |
### Question: Is traffic-related air pollution exposure associated with allergic sensitization , asthma , and poor lung function in middle age? ### Context: Traffic-related air pollution (TRAP) exposure is associated with allergic airway diseases and reduced lung function in children, but evidence concerning adults, es... |
### Question: Is the association between temperature and mortality modified by age, gender and socio-economic status? ### Context: A number of studies have examined the relationship between high ambient temperature and mortality. Recently, concern has arisen about whether this relationship is modified by socio-demograp... |
### Question: Are cardiac structure and function altered in adults with non-alcoholic fatty liver disease? ### Context: Non-alcoholic fatty liver disease (NAFLD) is associated with a twofold greater risk of developing cardiovascular disease. Despite this, little is known about the effect of NAFLD upon cardiac function,... |
### Question: Does long-term treatment with TGFbeta1 impair mechanotransduction in bovine aortic endothelial cells? ### Context: Vascular endothelial cells play a role in the physiological response to mechanical stress. Transforming growth factor beta1 (TGFbeta1) induces morphological changes in endothelial cells, and ... |
### Question: Are serum concentrations of beta-carotene and alpha-tocopherol associated with diet , smoking , and general and central adiposity? ### Context: Previous studies of associations between diet, obesity, and blood concentrations of alpha-tocopherol and beta-carotene have been equivocal. Furthermore, most stud... |
### Question: Should Intravenous Contrast be Administered in MRI Evaluation of Pediatric Outpatients with Chronic Headache? ### Context: The practice of administering intravenous contrast to children varies by institution depending on their routine.To assess the necessity of routine contrast administration in brain mag... |
### Question: Is for avid glucose tumors , the SUV peak the most reliable parameter for [ ( 18 ) F ] FDG-PET/CT quantification , regardless of acquisition time? ### Context: This study is an assessment of the impact of acquisition times on SUV with [(18)F]FDG-PET/CT on healthy livers (reference organ with stable uptake... |
### Question: Does magnetic resonance support vector machine discriminate essential tremor with rest tremor from tremor-dominant Parkinson disease? ### Context: The aim of the current study was to distinguish patients who had tremor-dominant Parkinson's disease (tPD) from those who had essential tremor with rest tremor... |
### Question: Does a Strong B-cell Response be Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases? ### Context: In high-grade serous ovarian cancer (HGSOC), higher densities of both B cells and the CD8Unmatched pre and post-chemotherapy HGSOC metastases were studied. B-cell localization was asse... |
### Question: Is early enteral feeding in conservatively managed stage II necrotizing enterocolitis associated with a reduced risk of catheter-related sepsis? ### Context: To compare the effect of fasting period duration on complication rates in neonates managed conservatively for necrotizing enterocolitis (NEC) Bell s... |
### Question: Does sMOKING be A RISK FACTOR FOR PROLIFERATIVE VITREORETINOPATHY AFTER TRAUMATIC RETINAL DETACHMENT? ### Context: To determine the incidence of retinal redetachment due to proliferative vitreoretinopathy after open-globe trauma in smokers and nonsmokers.A total of 892 patients comprising 893 open-globe i... |
### Question: Are localization of antibodies on spermatozoa and sperm movement characteristics good predictors of in vitro fertilization success in cases of male autoimmune infertility? ### Context: To define sperm factors related to in vitro fertilization (IVF) failure in cases of antisperm autoimmunity.A detailed ana... |
### Question: Is ser ( P ) -1292 LRRK2 in urinary exosomes elevated in idiopathic Parkinson 's disease? ### Context: Mutations in Leucine-rich repeat kinase 2 (LRRK2) enhance levels of the autophosphorylated LRRK2 protein and are the most common known cause of inherited Parkinson's disease (PD). LRRK2 has been further ... |
### Question: Is perilipin-5 regulated by statins and controls triglyceride contents in the hepatocyte? ### Context: Perilipin-5 (PLIN5) is a member of the perilipin family of lipid droplet (LD)-associated proteins. PLIN5 is expressed in oxidative tissues including the liver, and is critical during LD biogenesis. Studi... |
### Question: Does active immunotherapy with transiently transfected cytokine-secreting tumor cells inhibit breast cancer metastases in tumor-bearing animals? ### Context: Metastatic disease remains the most frequent cause of treatment failure in the management of patients with breast cancer. A novel method that allows... |
### Question: Does duration of antibiotics after microsurgical breast reconstruction change surgical infection rate? ### Context: Infection rates for breast surgery are 3 to 15 percent, higher than average for a clean surgical procedure. Preoperative and postoperative antibiotics have lowered infection rates in other s... |
### Question: Is qT dispersion related to infarct size or inducibility in patients with coronary artery disease and life threatening ventricular arrhythmias? ### Context: To relate QT parameters to infarct size and inducibility during electrophysiological studies.Analysis of a prospective register.University hospital.6... |
### Question: Is arterial wall hyperplasia increased in placental compared with myoendometrial radial uterine arteries from late-pregnant rats? ### Context: This study compared myoendometrial versus placental radial uterine arteries from late-pregnant rats to evaluate differences in passive mechanical properties and ar... |
### Question: Is elevated plasma homocysteine concentration in elderly patients with mental illness mainly related to the presence of vascular disease and not the diagnosis? ### Context: Plasma total homocysteine (tHcy) is often elevated in patients with mental illness. Since patients with mental illness and vascular d... |
### Question: Is neither long-term statin use nor atherosclerotic disease associated with risk of colorectal cancer? ### Context: Statin use has been reported to reduce risk for colorectal cancer (CRC) whereas atherosclerotic disease has been reported to increase risk, but findings have been inconsistent. We aimed to e... |
### Question: Does gonadotropin releasing hormone ( GnRH ) agonist induce down-regulation of the CD3+CD25+ lymphocyte subpopulation in peripheral blood? ### Context: To test whether GnRH agonist could alter in vivo human immune cells and whether the alteration is related to the success of pregnancy in an in vitro ferti... |
### Question: Do the effectiveness of four methods for stain removal from direct resin-based composite restorative materials? ### Context: Few studies investigated the best method for removing stains from different types of resin-based composite restorations and compared them to the more recently introduced nanocomposi... |
### Question: Do probiotics inhibit immune fluctuation in the intestinal mucous layer in rats? ### Context: Innate lymphocytes play a key role in maintaining the immune bowel barrier, which provides resistance to infection. However, the effects of probiotics on changes in the function of innate lymphocytes in the posto... |
### Question: Is the ankle brachial index associated with prognosis in patients with diabetic kidney disease? ### Context: Peripheral arterial disease (PAD) could be an additional risk factor for the clinical outcomes in different populations. The purpose of this study was to evaluate the influence of PAD on patients w... |
### Question: Are higher serum nitrate levels associated with poor survival in lung cancer patients? ### Context: Angiogenic factors induce tumour growth and angiogenesis which leads to tumour metastasis and a poor survival rate. This study aimed to assess the possible roles of nitric oxide (NO) and vascular endothelia... |
### Question: Does loss of function mutation in toll-like receptor-4 offer protection against obesity and insulin resistance induced by a diet high in trans fat in mice? ### Context: Toll-like receptor-4 (TLR4) triggers inflammatory signaling in response to microbial lipoploysaccharide. It has been reported that loss o... |
### Question: Does gastric Anatomic Type be Associated with Obesity and Gender? ### Context: To enhance our understanding of the associations among gastric anatomy, obesity, and gender.777 randomly selected participants received health checkups, including a series of radiographs of the upper gastrointestinal tract (UGI... |
### Question: Is eplerenone superior to older and less expensive aldosterone antagonists? ### Context: Eplerenone is publicized to be extremely effective in reducing mortality from heart failure, with a reasonable side-effect profile. However, it is much more expensive compared with older aldosterone antagonists. We re... |
### Question: Does strand-specific RNA-Seq reveal widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum? ### Context: Advances in high-throughput sequencing have led to the discovery of widespread transcription of natural antisense transcripts (NATs) in a large... |
### Question: Do mesenchymal stem cells overexpressing MiR-126 enhance ischemic angiogenesis via the AKT/ERK-related pathway? ### Context: This study was designed to examine whether transplantation of mesenchymal stem cells (MSCs) overexpressing miR-126 enhances angiogenesis in the infarcted myocardium of mice.MSCs wer... |
### Question: Is plasma atrial natriuretic peptide elevated in patients with hypertrophic cardiomyopathy? ### Context: To determine if plasma levels of atrial natriuretic peptide are elevated in patients with hypertrophic cardiomyopathy and to determine the relationship of atrial natriuretic peptide to symptoms and ech... |
### Question: Is irbesartan projected to be cost and life saving in a Spanish setting for treatment of patients with type 2 diabetes , hypertension , and microalbuminuria? ### Context: The purpose of this study was to project the cumulative incidence of end-stage renal disease (ESRD), life expectancy, and costs in a Sp... |
### Question: Pulmonary valve replacement in adults late after repair of tetralogy of fallot: are we operating too late? ### Context: The purpose of this study is to evaluate right ventricular (RV) volume and function after pulmonary valve replacement (PVR) and to address the issue of optimal surgical timing in these p... |
### Question: Does extended-release trospium chloride improve quality of life in overactive bladder? ### Context: Overactive bladder syndrome (OAB) is a urinary condition that often exerts detrimental effects on an individual's quality of life (QoL). A once-daily, extended-release (ER) formulation of the quaternary ami... |
### Question: Insured versus uninsured patients in the emergency room: is there a difference? ### Context: To define the differences in emergency room usage patterns between patients with and without medical insurance coverage.A retrospective analysis of the database of 34 642 consecutive patient visits to an urban hos... |
### Question: Does olfactory stimulation by vanillin prevent apnea in premature newborn infants? ### Context: Apnea is one of the most common problems in premature newborns. The present study aimed to determine the effect of olfactory stimulation by vanillin on prevention of apnea in premature newborns.In this randomiz... |
### Question: Is intestinal biopsy always needed for diagnosis of celiac disease? ### Context: Intestinal biopsy is required for a diagnosis of celiac disease (CD). The aim of this study was to assess diagnostic accuracy of transglutaminase antibodies (TGA) in comparison and in association with that of antiemdomysial a... |
### Question: Do aberrant cytokines/chemokines production correlate with proteinuria in patients with overt diabetic nephropathy? ### Context: Diabetic nephropathy (DN) occurs in 20% to 30% of all patients with type 2 diabetes mellitus (DM) and is the most common cause of end-stage renal disease. However, the definite ... |
### Question: Does serum 25-hydroxyvitamin D predict severity and prognosis in stroke patients? ### Context: We aimed to evaluate the association between 25-hydroxyvitamin D (25(OH)D) levels and both clinical severity at admission and outcome at discharge in stroke patients.From February 2010 to December 2010, consecut... |
### Question: Are gender differences associated with the clinical features of systemic lupus erythematosus? ### Context: Systemic lupus erythematosus (SLE) mostly occurred in young women. This study was undertaken to investigate the different clinical characteristics of SLE between male and female patients, and to iden... |
### Question: Does inflammation-based prognostic score predict biliary stent patency in patients with unresectable malignant biliary obstruction? ### Context: An inflammation-based prognostic score, the modified Glasgow prognostic score (mGPS), has been reported to be useful for predicting postoperative survival in pat... |
### Question: Does change in filling pattern with preload reduction reflect left ventricular relaxation? ### Context: The early diastolic mitral valve pressure gradient and the rate of left ventricular filling are determined by the rate of left ventricular relaxation and left atrial pressure at the time of mitral valve... |
### Question: Is interleukin-12 essential for silicosis in mice? ### Context: Silicosis features foci of inflammation where macrophages and lymphocytes precede and accompany fibroblast proliferation, alveolar epithelial hyperplasia, and increased deposition of connective tissue matrix material. In the mouse following s... |
### Question: Are lumpectomy specimen margins reliable in predicting residual disease in breast conserving surgery? ### Context: In breast conserving surgery, the concordance between lumpectomy margin (LM) status and the status of the corresponding lumpectomy cavity remains uncertain.We analyzed pathology reports of lu... |
### Question: Is preoperative laparoscopy useful for impalpable testis? ### Context: Laparoscopic assessment of pelvic anatomy has gained wide popularity over the years. Today surgical treatment of impalpable testis is nearly always preceded by diagnostic laparoscopy. The actual role of such a procedure remains undefin... |
### Question: Are modified energy settings mandatory to minimize oesophageal injury using the novel multipolar irrigated radiofrequency ablation catheter for pulmonary vein isolation? ### Context: The multipolar irrigated radiofrequency (RF) ablation catheter (nMARQ™) is a novel tool for pulmonary vein isolation (PVI).... |
### Question: Does addition of 5-fluorouracil to doxorubicin-paclitaxel sequence increase caspase-dependent apoptosis in breast cancer cell lines? ### Context: The aim of the study was to evaluate the activity of a combination of doxorubicin (Dox), paclitaxel (Pacl) and 5-fluorouracil (5-FU), to define the most effecti... |
### Question: Does injury pattern in correlation with the height of fatal fall? ### Context: Death due to blunt trauma as a sequel of falls, as a cause of an increased life span is expected. The aim of this retrospective study was to examine the correlation between the height of fall and the frequency, the extensivenes... |
### Question: Are sleep deprivation , physical activity and low income risk factors for inadequate weight gain during pregnancy : a cohort study? ### Context: To determine the possible risk factors for inadequate gestational weight gain.A population-based cohort study was carried out in Sri Lanka from May 2001 to April... |
### Question: Do nutritional screening tools and anthropometric measures associate with hospital discharge outcomes in older people? ### Context: To examine the association of nutritional screening tools (NSTs) and anthropometric measures with hospital outcomes in older people.In 172 patients aged ≥70 years admitted to... |
### Question: Does capsule endoscopy improve outcomes in obscure gastrointestinal bleeding? ### Context: Capsule endoscopy improves the diagnostic yield in patients with obscure gastrointestinal (GI) bleeding, but whether it improves outcomes is uncertain.Patients with obscure GI bleeding and negative upper endoscopy, ... |
### Question: Is phosphorylation of cAMP response element-binding protein in the extended amygdala of male rats induced by novel environment and attenuated by estrous female-bedding? ### Context: We examined whether female pheromone, which would be contained in female-soiled bedding, affected the expression of phosphor... |
### Question: Pancreatogram findings for carcinoma in situ (CIS) of the pancreas seen on endoscopic retrograde cholangiopancreatography and postoperative pancreatography of resected specimens: can CIS be diagnosed preoperatively? ### Context: From 1992 to 2003, 7 carcinomata in situ (CIS) were incidentally discovered d... |
### Question: Do chemical compounds that target thiol-disulfide groups on mononuclear phagocytes inhibit immune mediated phagocytosis of red blood cells? ### Context: Patients having immune cytopenias produce antibodies that target hematopoietic cells resulting in their phagocytosis and intracellular destruction. Early... |
### Question: Is abundance of interstitial eosinophils in renal allografts associated with vascular rejection? ### Context: The authors investigated the possible relevance of significant interstitial graft eosinophilic infiltrate (SIGEI) to the pathologic diagnosis of renal transplants.The authors performed a clinical ... |
### Question: Do IgA, IgE, and IgG avidity tests have any value in the diagnosis of toxoplasma infection in pregnancy? ### Context: In a retrospective study, current serological tests (dye test and three IgM assays with different sensitivities) were compared with immunosorbent agglutination assays (ISAGA) for specific ... |
### Question: Does ethanol washing attenuate the hypocholesterolemic potential of soy protein? ### Context: A feeding study in rats investigated the principal active component for the hypocholesterolemic effect of soy protein isolate (SPI) by comparing the effect before and after ethanol washing.Five-week-old male Spra... |
### Question: Do human retinal Müller cells synthesize collagens of the vitreous and vitreoretinal interface in vitro? ### Context: To investigate the capacity of cultured Müller cells to synthesize collagens, since previous studies indicated that Müller cells could be involved in collagen remodeling at the vitreoretin... |
### Question: Does bilirubin treatment suppress pulmonary inflammation in a rat model of smoke-induced emphysema? ### Context: Cigarette smoking is a significant risk factor for emphysema, which is characterized by airway inflammation and oxidative damage.To assess the capacity of bilirubin to protect against smoke-ind... |
### Question: Is off-pump bypass grafting safe in patients with left main coronary disease? ### Context: Because of a concern about the ability to tolerate beating heart grafting, patients with left main coronary artery stenosis have been excluded from off-pump bypass. We reviewed our experience with off-pump coronary ... |
### Question: Does theory of Reasoned Action predict milk consumption in women? ### Context: To determine the factors influencing the consumption or avoidance of milk in women.One hundred women completed food frequency questionnaires and a milk attitudes questionnaire framed within the Theory of Reasoned Action and per... |
### Question: Does hearing lead to understanding? ### Context: Theory of Mind (ToM) refers to the ability to understand the subjectivity of people's intentions, desires, and beliefs. Research shows that ToM in deaf children is delayed, yet the few studies that examined ToM in deaf children with a cochlear implant (CI) ... |
### Question: Is gH response to growth hormone releasing hormone and hypoglycaemia unaltered by high endogenous plasma calcitonin levels in patients with medullary thyroid carcinoma? ### Context: As it has previously been reported that calcitonin suppresses stimulated growth hormone release, we have studied the serum g... |
### Question: Sternal fracture in growing children : A rare and often overlooked fracture? ### Context: Sternal fractures in childhood are rare. The aim of the study was to investigate the accident mechanism, the detection of radiological and sonographical criteria and consideration of associated injuries.In the period... |
### Question: Does elevated childhood serotonergic function protect against adolescent aggression in disruptive boys? ### Context: This longitudinal study examined whether responsiveness of the neurotransmitter serotonin (5-HT) in childhood predicts adolescent aggression.Boys (N = 33) with disruptive behavior disorders... |
### Question: Does sleep restriction worsen mood and emotion regulation in adolescents? ### Context: The relationship between inadequate sleep and mood has been well-established in adults and is supported primarily by correlational data in younger populations. Given that adolescents often experience shortened sleep on ... |
### Question: Does psychosocial and lifestyle correlate of premenstrual symptoms among military women? ### Context: This study examines the prevalence and correlates of self-reported premenstrual symptoms among a large, population-based sample of reproductive age, active-duty women.Data were obtained from a combined da... |
### Question: Do chemokine receptors CXCR2 and CX3CR1 differentially regulate functional responses of bone-marrow endothelial progenitors during atherosclerotic plaque regression? ### Context: Atherosclerosis manifests itself as arterial plaques, which lead to heart attacks or stroke. Treatments supporting plaque regre... |
### Question: Comparing the toxicity of digoxin and digitoxin in a geriatric population: should an old drug be rediscovered? ### Context: Little information is available regarding toxicity rates of the two available forms of cardiac glycosides (digoxin, digitoxin) when used in elderly patients.We retrospectively analyz... |
### Question: Thromboembolism in chronic atrial flutter: is the risk underestimated? ### Context: We sought to evaluate the risk of thromboembolic events in the presence of chronic atrial flutter and to determine the impact of anticoagulation therapy, if any, on this risk.Thromboembolic events are thought to be rare af... |
### Question: Employment in retirement: continuation of a working career or essential additional income? ### Context: This article investigates employment of retired persons with different ethnic backgrounds, namely Germans, ethnic Germans and immigrants. The central issue of this paper addresses the influencing factor... |
### Question: Do elevated plasma thrombomodulin and angiopoietin-2 predict the development of acute kidney injury in patients with acute myocardial infarction? ### Context: Acute kidney injury (AKI) following acute myocardial infarction (AMI) is associated with unfavorable prognosis. Endothelial activation and injury w... |
### Question: Defining the optimal spacing between repeat radioantibody doses in experimental models: is there an accurate measurement for hematopoietic recovery? ### Context: Single doses of radioantibody are effective at treating single cells or small clusters of cancer cells. However, large tumor masses require eith... |
### Question: Does the choice of mobile C-arms lead to a reduction of the intraoperative radiation dose? ### Context: Mobile C-arm imaging is commonly used in operating rooms worldwide. Especially in orthopaedic surgery, intraoperative C-arms are used on a daily basis. Because of new minimally-invasive surgical procedu... |
### Question: Are polymorphisms in ADAM33 associated with allergic rhinitis due to Japanese cedar pollen? ### Context: A recent report provided evidence that a disintegrin and metalloprotease domain 33 (ADAM33), a member of the ADAM family, is a novel susceptibility gene in asthma linked to bronchial hyper-responsivene... |
### Question: Does hyperventilation elicit epileptic seizures? ### Context: Voluntary hyperventilation has been advocated for many decades as an "activating" procedure to provoke clinical seizures and epileptiform discharges in subjects with suspected epilepsy who undergo standard EEG recordings. This study was underta... |
### Question: Does variation in IgG1 heavy chain allotype contribute to differences in biological activity of two human anti-Rhesus ( D ) monoclonal antibodies? ### Context: Pooled human anti-Rhesus D antiserum is currently administered for the prevention of RhD alloimmunization. Increased demand, and decreased supply,... |
### Question: Do monocytes from metabolic syndrome subjects exhibit a proinflammatory M1 phenotype? ### Context: The metabolic syndrome is a highly prevalent state affecting one in three US adults and comprises a cluster of cardiometabolic risk factors. While metabolic syndrome is a proinflammatory state, there is a pa... |
### Question: Do medical students respond empathetically to a virtual patient? ### Context: Significant information exchange occurs between a doctor and patient through nonverbal communication such as gestures, body position, and eye gaze. In addition, empathy is an important trust-building element in a physician: pati... |
### Question: Does monitoring of loss of heterozygosity in serum microsatellite DNA among patients with gastrointestinal stromal tumors indicate tumor recurrence? ### Context: Patients with gastrointestinal stromal tumors (GIST) harbor increased levels of circulating tumor DNA in their peripheral blood. In the current ... |
### Question: Mechanical thrombectomy with the Trevo ProVue device in ischemic stroke patients: does improved visibility translate into a clinical benefit? ### Context: To investigate the efficacy and safety of the Trevo ProVue (TPV) stent retriever in stroke patients with large artery occlusions, with particular atten... |
### Question: Do dendritic cells combining with cytokine-induced killer cells synergize chemotherapy in patients with late-stage non-small cell lung cancer? ### Context: Lung cancer is the leading cause for cancer-related mortality and morbidity, and the survival of late-stage non-small cell lung cancer (NSCLC) remains... |
### Question: Is Enterobius vermicularis infestation associated with acute appendicitis? ### Context: Enterobius vermicularis might be seen in specimens of patients who underwent surgery due to acute appendicitis. There is still debate as to E. vermicularis infestation causes acute appendicitis. The primary aim of this... |
### Question: Does prestorage gamma irradiation induce oxidative injury to red cells? ### Context: Gamma irradiation of blood results in the formation free radicals, which interact with lipids and proteins in the membranes of red blood cells. We have investigated oxidative injury to gamma-irradiated red cells by measur... |
### Question: Do radiation-blocking glasses allow vision during ophthalmic plaque radiation therapy? ### Context: To evaluate the use of leaded safety glasses to block radiation and allow for vision during ophthalmic plaque radiation therapy.Interventional case series.Eight patients were treated with palladium 103 opht... |
### Question: Do location of positive surgical margin and its association with biochemical recurrence rate differ significantly in four different types of radical prostatectomy? ### Context: To analyze the location of the positive surgical margin (PSM) and its association with the biochemical recurrence (BCR) rate in c... |
### Question: Do phylogeography and historical demography of the Lusitanian snail Elona quimperiana reveal survival in unexpected separate glacial refugia? ### Context: Present day distributions of Palearctic taxa in northern latitudes mainly result from populations having survived in local patches during the Late Plei... |
### Question: Are serum levels of advanced glycation end products ( AGEs ) inversely associated with the number and migratory activity of circulating endothelial progenitor cells in apparently healthy subjects? ### Context: Endothelial progenitor cells (EPCs) have been shown to participate in the process of vascular re... |
### Question: Are pathways of carcinogenesis reflected in patterns of polyp pathology in patients screened for colorectal cancer? ### Context: There are multiple genetic routes to colorectal cancer, including chromosomal instability, mismatch repair dysfunction, and global hypermethylation. Few consider the possibility... |
### Question: Does nectin-like molecule-5 regulate intimal thickening after carotid artery ligation in mice? ### Context: Intimal thickening is considered to result from the dedifferentiation of medial smooth muscle cells (SMCs) from a contractile to a synthetic phenotype, and their subsequent migration and proliferati... |
### Question: Does lipoteichoic acid from Staphylococcus aureus enhance allergen-specific immunoglobulin E production in mice? ### Context: Our previous study demonstrated that lipoteichoic acid (LTA) from Staphylococcus aureus induced T helper type 2 (Th2)-prone dermatitis resembling that seen in atopic dermatitis (AD... |
### Question: Does inhibition of white blood cell adhesion at reperfusion decrease tissue damage in postischemic striated muscle? ### Context: To determine the impact of white blood cell (WBC)-endothelium adhesion on tissue damage in the setting of ischemia-reperfusion injury in striated muscle.The cremaster muscle of ... |
### Question: Does transition to the adult nephrologist induce acute renal transplant rejection? ### Context: In spite of the overall increased renal graft survival, long-term allograft survival has remained least successful in adolescent recipients. A major change in their care is the transition from the paediatric to... |
### Question: Do intrasac flow velocities predict sealing of type II endoleaks after endovascular abdominal aortic aneurysm repair? ### Context: The purpose of this study was to determine whether intrasac spectral Doppler flow velocities can predict whether or not a type II endoleak will spontaneously seal and to relat... |
### Question: Is the MCH ( 1 ) receptor , an anti-obesity target , allosterically inhibited by 8-methylquinoline derivatives possessing subnanomolar binding and long residence times? ### Context: Melanin-concentrating hormone receptor 1 (MCH1 receptor) antagonists are being considered as anti-obesity agents. The presen... |
### Question: Is arg188 in rice sucrose transporter OsSUT1 crucial for substrate transport? ### Context: Plant sucrose uptake transporters (SUTs) are H+/sucrose symporters related to the major facilitator superfamily (MFS). SUTs are essential for plant growth but little is known about their transport mechanism. Recent ... |
### Question: Does limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 support the development of effective multi-allele vaccines? ### Context: Polymorphism in antigens is a common mechanism for immune evasion used by many important pathogens, and presents major challenges in vaccine developm... |
### Question: Does microRNA-130b regulate the tumour suppressor RUNX3 in gastric cancer? ### Context: Accumulating evidence indicates that RUNX3 is an important tumour suppressor that is inactivated in many cancer types. This study aimed to assess the role of microRNA (miRNA) in the regulation of RUNX3.Four bioinformat... |
### Question: Is advanced parental age at birth associated with poorer social functioning in adolescent males : shedding light on a core symptom of schizophrenia and autism? ### Context: Evidence indicates an association between older parents at birth and increased risk for schizophrenia and autism. Patients with schiz... |
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