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135
8d9a9100-31de-4735-bd40-479d139c0e63
Characteristic feature of Goodpasture's syndrome
Lumpy-bumpy deposits on immunofluorescence
Serum antibodies against alpha 3 NC1 domain of collagen - IV
Serum antibodies against alpha 1 NCI domain of collagen III
Anti DNAse antibodies positive
1b
single
Ans. (b) Serum antibodies against alpha 3 NC1 domain of collagen - IV(Ref: Robbins 9th/pg 912-913)Goodpasture syndromeIt is type 1 RPGN & a type II hypersensitivity reaction.It is characterized by serum antibodies against alpha 3 NC1 domain of collagen - IV.This shows linear GBM fluorescence, while all other Glomerulon...
Pathology
Kidney
372a754e-08b4-448e-8de6-16dd013941cd
Puppe's rule is associated with?
Sexual assault
Multiple impact injuries
Chemical injuries
Percentage of burns
1b
single
Puppe's rule is associated with multiple impact injuries. PUPPE'S RULE It states that when two fracture lines intersect each other, the second fracture line never crosses the first one. It tells us the sequence of shots when multiple bullets have struck the skull, and it is also applicable to the multiple blunt impacts...
Forensic Medicine
Mechanical Injuries
e1761ffa-a0f4-4815-9981-b5bcca82b757
If the 4% of thymine residues in DNA is 28% what is the % of cystosine
28%
44%
36%
22%
3d
single
this is solved acc to chargaff rules = A+T+G+C=100% REF : LIPINCOTT BIOCHEMISTRY
Biochemistry
All India exam
8482818b-12da-4982-9922-57934754518b
Which one of the following phenomenon is closely associated with slow wave sleep -
Dreaming
Sleep walking
Atonia
Irregular heart rate
1b
single
Slow wave sleep (stage 3 & 4 of NREM sleep) disorders:- Sleepwalking (somnambulism), night tenor (sleep terror or pavomoctumus), Nocturnal enuresis, Bruxism (teeth grinding), and sleep talking (somniloquy). REM sleep events/disorder :- Nightmares, nocturnal penile tumescence, Narcolepsy.
Psychiatry
null
0aed7f16-45cf-467b-b7d9-d01d0e8914c3
Which of the following signs of congestive cardiac failure constitute a major risk to the surgical patient undergoing anaesthesia ?
Jugular venous distention and third heart sound
Cardiomegaly
Pedal oedema
Basal crepitations on auscultation
0a
single
Higher perioperative risk is seen with :- Systemic hypertension, elevated jugular venous pressure, pulmonary rales, the presence of third heart sound, murmurs suggestive of significant valvular disease, and vascular bruits.
Anaesthesia
null
ad131fed-6354-4ad7-be5e-7d95e26f499a
All are true about treatment of migraine EXCEPT:
Naratriptan acts longer than sumatryptan
Sumatryptan is used in acute attack of migraine
Sumatryptan acts on 5HT. B/D receptors in great vessels
Sumatryptan is used for chronic migraine
3d
multi
ANSWER: (D) Sumatryptan is used for chronic migraineREF: Harrison's 17th ed chapter 15"By chronic migraine the examiner means to say prevention of migraine and sumatryptan is not used in prevention of migraine, but in acute attackNaratriptan, administered orally, reaches its peak plasma concentration in 2-3 hours and h...
Medicine
C.N.S.
b9752b65-8408-4f4d-8830-9002806bcd9e
Which of the following best describes the mechanism of action of d-Tubocurarine?
Competitive, non-depolarising block at Nm cholinergic receptors
Competitive , depolarising block at Nm cholinergic receptors
Non-competitive, non-depolarising block at Nm cholinergic receptors
Non-competitive, depolarising block at Nm cholinergic receptors
0a
single
D-tubocurarine is the prototype Non-depolarising neuromuscular blocking agents that causes a Competitive, non-depolarising block at Nicotinic (Nm) cholinergic receptors. Mechanism of Action of d-Tubocurarine and other Non-Depolarising Competitive Blockers: At low doses (Competitive Block) At high doses (Complete Blocka...
Pharmacology
Autonomic nervous system
132fa187-9ec5-43d6-bfaf-55d5910655c7
A patient of CSOM with cholesteatoma present with acute onset of veigo. Treatment is:
Immediate exploration
Antibiotics + steroids
Labyrinthine sedatives + antibiotics
Labyrinthine sedatives only
0a
single
Ans. A CSOM with cholesteatoma is the most common cause of labyrinthus, presents with transient veigo often induced by pressure on tragus, cleaning the ear or while performing val salva monoeuure * Coical mastoidectomy (in acute mastoiditis) or modified radical mastoidectomy (in chronic middle ear infection or choleste...
ENT
null
41aa38be-7a52-43aa-99e6-26e9ecc87a21
The sensory supply of the palate is through all of the following, except
Facial nerve
Hypoglossal nerve
Glossopharyngeal nerve
Maxillary division of trigeminal nerve
1b
multi
.
Anatomy
All India exam
83dcf2bd-6d11-425a-895d-68b24f4ff9db
Keratomalacia is due to -
Vit-A deficiency
Keratoconus
Vitamin E deficiency
Also seen in retinitis pigmentosa
0a
single
Ans. is 'a' i.e., Vit-A deficiency o Keratomalacia It is a common condition in developing countries and is due to deficiency of vitamin A.o The condition is usually bilateral.o In keratomalacia, the cornea becomes dull and insensitive, hazy and yellow infiltrates form until finally the whole tissue undergoes necrosis a...
Ophthalmology
Cornea
a15ab624-2911-4cd9-9e79-291b349a1d9a
Yersinia enterocolitica, formerly a Pasteurella, has more than 50 sero-types that can be isolated from rodents, sheep, cattle, swine, dogs, and cats and water contaminated by them, and is best described by which of the following?
Commonly inhabits the canine respiratory tract and is an occasional pathogen for humans; strongly urease-positive
Gram-negative bipolar stained bacilli that cause diarrhea by means of a heat-stable enterotoxin, with abdominal pain that may be mistaken for appendicitis
Pits agar, grows both in carbon dioxide and under anaerobic conditions, and is part of the normal oral cavity flora
Typically infects cattle, requires 5% to 10% carbon dioxide for growth, and is inhibited by the dye thionine
1b
multi
All the organisms are short, ovoid, gram-negative rods. For the most part, they are nutritionally fastidious and require blood or blood products for growth. These and related organisms are unique among bacteria in that, though they have an animal reservoir, they can be transmitted to humans. Humans become infected by a...
Microbiology
Bacteria
83eeacb4-9bce-4af3-b4c0-5ba9911c8140
In pterygium, which layer of cornea is involved most often -
Epithelium
Endothelium
Bowman's layer
Descemet's membrane
2c
single
Pterygium is a growth from conjunctiva, In cornea, it involves Bowman&;s layer. Reference : Yanoff & Duker 3rd edition ,page :712
Ophthalmology
Conjunctiva
9a3e2aa9-a4b3-4745-850f-b113a6ec519f
Anticoagulant of choice for prophylaxis of venous thromboembolism in patient with cancer surgery is:-
Heparin sulfate
Protamine sulfate
Low molecular weight heparin
Warfarin
2c
single
Venous Thromboembolism- precipitating factor -estrogen in females PREVENTION OF Venous Thromboembolism AMONG HOSPITALIZED PATIENTS Condition Prophylaxis High risk non - ohopedic surgery Unfractionated heparin Low molecular weight heparin (LMWH) Cancer surgery(associated thromboembolism ) LMWH Major ohopedic surgery War...
Pharmacology
Hematology
8927a11d-2af1-47e2-9275-1f2fe6a68be8
In MCH programme the sampling is done by which method-
Systemic
Stratified
Group
Cluster-30
3d
single
Ans. is 'd' i.e., Cluster-30
Social & Preventive Medicine
null
9b67ab79-55ec-4005-91e0-9874ad934308
A 60-year-old male, chronic smoker, presented with fatigue and chest pain. On examination, there was inset left eyeball with drooping upper left eyelid and reduced left pupil size. Which of the following is the most likely diagnosis in this condition?
Squamous cell carcinoma involving the apex of his left lung
Adenocarcinoma involving left mainstem bronchus
A small-cell carcinoma involving the hilum of his left lung
Bronchioloalveolar carcinoma involving the left lower lobe
0a
multi
Most tumors of the apex of the lung are adenocarcinomas Pancoast tumors - apical lung tumors in the superior pulmonary sulcus tend to invade the neural structures around the trachea, including the cervical sympathetic plexus. Involvement of sympathetic fibers gives rise to severe pain in the distribution of the ulnar n...
Pathology
Lung Tumor
f70683c6-b7ae-4d6d-9001-28746e4a5615
Bleeding that follows paial or complete placental separation and dilation of the cervical os in first 20 weeks is termed as
Threatened aboion
Complete aboion
Incomplete aboion
Preterm labor
2c
single
Incomplete Aboion: Bleeding that follows paial or complete placental separation and dilation of the cervical os is termed incomplete aboion. The fetus and the placenta may remain entirely within the uterus or paially extrude through the dilated os. Management options of incomplete aboion include curettage, medical aboi...
Gynaecology & Obstetrics
All India exam
c8385127-dbcd-4a33-b308-768c0e02b178
Drug with both antidepressant and antipsychotic propeies is?
Buspirone
Amoxapine
Trazodone
Minaserine
1b
multi
Ans. is 'b' i.e., Amoxapine o Amoxapine is the only antidepressant which blocks D2 receptors along with inhibition of NA reuptake --> has mixed antidepressant + neurolepic propey.
Pharmacology
null
524bc02e-c750-4342-bf19-f9fa01a6879e
All of the following are products of oxygenase pathway, EXCEPT:
PGE2
PGD2
PGF2
LT6
3d
multi
Arachidonate, which may be obtained from the diet, but is usually derived from the 2 position of phospholipids in the plasma membrane by the action of phospholipase A2,is the substrate for the synthesis of the PG2, TX2 series (prostanoids) by the cyclooxygenase pathway, or the LT4 and LX4 series by the lipoxygenase pat...
Biochemistry
null
e181fa74-7b41-40c5-a13a-879082db3c2d
Long term complications of bronchopulmonary dysplasia are all except :
Decreased FRC
Small airway disease
Large airway disease
Interstitial lung disease
2c
multi
Large airway disease Bronchopulmonary dysplasia is clinically diagnosed in neonate <32 weeks of gestation who requires at least 28 days of oxygen therapy. It is now infrequent in infants> 1200 gm of bih weight & gestation >30 wks. Histology : * Airway epithelial hyperplasia * Squamous metaplasia * Alveolar wall thicken...
Surgery
null
b24deff0-d5f3-4ea1-93a4-ea7dddc5ce97
A 31-year-old male patient complains of fatigue, yeast infection in his mouth, and enlarged lymph nodes under his arms. He said that he was involved in "high-risk" behavior 6 years ago while on a trip to eastern and southern Africa. He also indicated that his "HIV test" was negative. Which one of the following options ...
Initiate treatment for HIV disease
Order a test for human T cell leukemia virus (HTLV)
Repeat the test for HIV-1
Order an HIV test which would include antibodies to HIV-1 and HIV-2
3d
multi
HIV-2 is present in Africa, the Far East, and some pas of the Caribbean area. Many of the screening tests for HIV-1 will not detect antibodies to HIV-2. Either a separate HIV-2 antibody test or a combination HIV-1/2 is necessary. While HTLV disease is also seen in the same geographic areas, the symptoms are more akin t...
Microbiology
Immunology
b53aa4ed-4123-45cd-a8b9-f89c95aeb67e
How many lactiferous ducts open into nipple
0-10
15-20
25-50
50-75
1b
single
The gland consists of 15 to 20 lobes.Each lobe is a cluster of alveoli,and is drained by a lactiferous duct.The lactiferous ducts converge towards the nipple and open on it.Near it's termination each duct has a dilatation called a lactiferous sinus. Ref.B D Chaurasia's human anatomy.vol.1
Anatomy
Thorax
e0db3f09-26f1-487d-99ae-0c083a6983bd
Maximum chances of ABO isoimmunization is seen in?
O+VE Mother to A+VE child
O+VE mother to B+VE child
A+VE mother to 0+VE child
B+VE mother to O+VE child
0a
single
TEXT BOOK OF PATHOLOGY HARSHMOHAN 6THEDITION PG NO 341 HDN due to ABO incompatibility. About 20% pregnancies with ABO incompatibility between the mother and the foetus develop the HDN. Naturally-occurring anti-A and anti-B antibodies' which are usually of IgM class do not cross the placenta, while immune anti-A and ant...
Pathology
General pathology
317b43be-4ce9-471b-b249-a574ccee541a
Pancreaticoduodenectomy is not indicated in:
Multiple cyst and calcifications in head of the pancreas
Duodenal cancer
Failed drainage procedure for chronic pancreatitis
Ampullary carcinoma with secondaries in peritoneum
3d
single
Pancreaticoduodenectomy Indications Contraindications Carcinoma head of pancreas & Ampullary carcinoma Cystic tumors of pancreas Chronic pancreatitis Duodenal carcinoma Common bile duct cancer(Cholangiocarcinoma) Mucinous cystadenoma Pancreatic trauma Metastatic disease in abdominal cavity or nearby organ
Surgery
Pancreas
d86bd3e3-b804-4f5c-beed-448ed7291e6f
Pain in endometriosis correlates with:
Depth of invasion
Multiple sites
CA 125
Stage of disease
0a
single
Ans. is a, i.e. Depth of invasionRef: Leon Speroff, 8/ed, pl230-1231"The intensity of pain associated with deeply infiltrating endometriosis relates to the depth of penetration and to the proximity or direct invasion of nerves". - Ref: Leon Speroff, 8th/ed, pl230"However there is no relationship between stage, site or ...
Gynaecology & Obstetrics
Endometriosis
db2ce0cd-6c51-4430-975e-349167aa2a91
The dibucaine number refers to
Ach cholinesterase activity derangement
Potency of muscle relaxants
Potency of general anaesthetics
None
0a
multi
Dibucaine number: Dibucaine (a local anaesthetic) inhibits 80% of normal pseudocholinesterase and 205 of atypical (non-functional) pseudocholinesterase. Therefore normal dibucaine number is 70-80%. The dibucaine number is used to measure the activity of atypical pseudocholinesterase.(Refer: stoelting's pharmacology and...
Anaesthesia
All India exam
df5a4187-8358-415b-a0e1-a26978635007
NADPH used in which pathway-
Fatty acid synthesis
Gluconeogenesis
Beta oxidation
Glycogenolysis
0a
single
Ans. is 'a' i.e., Fatty acid synthesisUses of NADPH:* Reductive biosynthesis of lipids# Fatty acid synthesis# Cholesterol synthesis# Steroid hormone synthesis# Fatty acid elongation# Bileacid synthesis
Biochemistry
Carbohydrates
fba17273-bad2-4239-898c-4d5e17ec1820
Enzyme activated by decrease in Insulin: glucagon ratio:
Glucokinase
Hexokinase
PFK
Glucose 6 phosphatase
3d
single
Low Insulin: Glucagon ratio means=Catabolicstate (Aslow insulinmeansFasting stateor catabolic state).Insulinis released in Fed state. So, in fasting stateglucose-6-phosphatasewill be active as this enzyme is involved ingluconeogenesis,which occurs duringfasting. OTHER OPTIONS OPTION A: Glucokinase phosphorylates glucos...
Biochemistry
NEET Jan 2020
14f13ea0-4aa2-4611-9c1a-8f4013e24401
Vigorous treatment of nephritis in SLE is indicated in:
Class I & II
Class III & IV
Class IV & V
Class V & VI
1b
single
Renal Biopsy in SLE: The pattern and severity of injury are impoant in diagnosis and selecting the best therapy. Aggressive immunosuppressive treatment is indicated in : Class III and IV disease Class V accompanied by III or IV disease Treatment for lupus nephritis is not recommended in class I or II disease or with ex...
Medicine
null
725ce302-c9cd-45b6-a8ee-6f58b878c6c5
Which of the following is not an example of pure gold restorative material?​
E-Z gold​
Electralloy​
Goldent​
Mat gold​
1b
multi
Direct gold restorations are the only type of restorations that use pure metal, namely gold, with the exception of one type of direct gold, i.e., electralloy. Direct gold materials can be classified into two main categories: precipitated gold and gold foil. Electralloy is an actual alloy of gold and calcium, with the c...
Dental
null
f62c6bf3-2a91-4ea1-bd4e-d4dbc475fa86
About foreign body in a child true statement is:
unilateral fetid discharge
Presents with unilateral nasal obstruction
Has torrential epistaxis
Inanimate is more common than animate
1b
multi
A,B and D Foreign Bodies in children cAn be Animate-larvae,maggots,beetles; Inanimate-peas,beans,dried pulses,nuts,paoee,cotton wool and pieces of pencil. Ref Dhingra 6/e,p 161;Turber 10/e,p 62.
ENT
Nose and paranasal sinuses
708e5fd6-3ef0-48cd-a8e5-2f853102204b
HPV is associated with ?
Carcinoma lung
Carcinoma brain
Carcinoma kidney
Carcinoma head neck
3d
single
Ans. is 'd' i.e., Carcinoma head neck Cancers associated with HPV are :?Cervical carcinomaAnal carcinomaVulvar carcinomaPenile carcinomaVaginal carcinomaOropharyngeal carcinoma (soft palate, base of tongue, tonsils).
Microbiology
null
6e420333-def7-481d-8f85-c6dbb047e4bb
Congenital pyloric stenosis causes: 1. Bilious vomiting 2. Non- bilious vomiting 3. Projectile vomiting 4. Non projectile vomiting 5. Forceful
1,2 & 4
2,3,4 & 5
1,3 & 4
All are seen
1b
multi
The vomiting in pyloric stenosis may or may not be projectile, however non bilious vomiting after feed is the characteristic feature. In about 10-15% of infants vomiting may contain blood. This bleeding is due to reflux esophagitis, a common association with hyperophic pyloric stenosis. Also know: Associated anomalies ...
Surgery
null
2d639973-c053-4510-997f-8653a7814c04
Coagulation defects a/w ↑ed coagulation is seen in: A) ↑ Protein C B) ↑ Protein B C) ↑ Anti Thrombin HE D) Protein C resistance E) Dysflbrtnogenemia
AC
BC
AB
DE
3d
single
Surgery Orthopedic, thoracic, abdominal andgenitourinary procedures Neoplasms Pancreas, lung, ovary, testes, urinary tract, breast, stomach Trauma Fractures of spine, pelvis, femur, or tibia; spinal cord injuries Immobilization Acute myocardial infarction, congestive heart failure,stroke,postoperative convalescence pre...
Pathology
null
eaa6cc79-6101-4062-a663-9cf53fb1d1c7
Vegans are those who -
Eat both dairy products and eggs
Eat dairy products but not eggs
Eat eggs but not dairy products
Neither eat dairy products nor eggs
3d
multi
Ans. is 'd' i.e., Neither eat dairy products nor eggs Vegetarionso Vegetarions are divided into three groups -A) Vegans (Vegan vegetarians)# Vegans do not eat any animal or dairy products like meat, fish, cheese or leather.# The get all the proteins from cereals, nuts and seeds.B) Lacto Vegetarians# These people eat da...
Social & Preventive Medicine
General
ccdc8188-563f-4acc-bcea-18372a5b8476
Most common chronic arthritis seen in children –
JRA
Rheumatic arthritis
Rheumatic fever
Sepsis
0a
single
Amongst the given option only JRA causes chronic arthritis in children. Arthritis Arthritis in children is diagnosed if - A) There is swelling or effusion in a joint B) There are any 2 of the following features - Decreased ROM     Pain  Tenderness Increased local temperature Differential diagnosis of arthritis Acu...
Pediatrics
null
eecb4b1e-db37-4a60-b8cf-293535497338
Most common organ involved in retroperitoneal fibrosis is -
Aorta
Ureter
Inferior vena cava
Sympathetic nerve plexus
1b
single
The most important clinical aspect of retroperitoneal fibrosis is that the fibrotic process frequently entraps and constricts the ureters thereby causing obstructive uropathy. Retroperitoneal fibrosis - It is a nonspecific, nonsuppurative inflammation of fibro-adipose tissue of unknown cause that produces symptoms by ...
Surgery
null
42d6390f-2c22-40fc-b328-91ce816c247c
Which of the following is the MOST common type of female pelvis?
Gynecoid
Anthropoid
Android
Platypelloid
0a
single
Gynecoid is the most common type of female pelvis. In this type of pelvis the inlet is oval or round. In the midpelvis, sides of the pelvis are straight and the spines are not prominent. At the outlet the pubic arch is wide and the sacrum is neither inclined anteriorly nor posteriorly. The configuration of this type of...
Gynaecology & Obstetrics
null
344d849d-fe32-41d8-853f-b02b41028d71
A 35 years old male comes with complain of baldness. On examination, well-defined bald patches were seen with no scarring. Small broken hairs were seen in the surrounding area. What is the likely diagnosis?
Androgenetic alopecia
Alopecia areata
Anagen effluvium
Telogen Effluvium
1b
multi
Ans: B. Alopecia areata(Ref Rooks 8/e p66.13, Fitzpatrick 6/e p732)Findings are highly suggestive of alopecia areata.The scalp appears normal in alopecia areata.In affected areas, anagen is abruptly terminated prematurely and affected hairs move prematurely into telogen, with resultant often precipitous hair shedding.T...
Skin
null
3c1f53d2-1eff-4a95-b61d-648a67c9e993
Antiepileptic of choice in post diabetic peripheral neuropathy?
Pregabalin
Amitryptyline
Carbamazepine
Duloxetine
0a
single
Ans. (a) PregabalinRef: Harrison's Internal Medicine 18/e, chapter 344, p 2984
Medicine
Seizures and Epilepsy
e7eb4966-860c-4cda-9f09-698e382b6be9
A patient has small, oval multiple ulcers in oral cavity with red erythematous margins. The diagnosis is ?
Carcinoma
Aphthous ulcer
Tubercular ulcer
Syphilitic ulcer
1b
multi
Ans. is 'b' i.e., Aphthous ulcer Aphthous ulcers They are painful, recurrent, superficial ulcers, usually involving movable mucosa, i.e. inner surfaces of lips buccal mucosa, tongue, floor of mouth and soft palate while sparing mucosa of the hard palate and gingivae. It has 2 forms - minor & major In the minor form, wh...
Surgery
null
852a8a3d-d0eb-40c1-9c02-73bee8178aa5
Uterine-cervix ratio upto 10 years is:
2:01
1:02
3:01
3:02
1b
single
Explanation: Age Uterus:cervix ratio Before pubey 1:2 At pubey 2:1 Adults in reproductive age 3:1 to 4:1 After menopause Generalised atrophy Ref: ANATOMY Shaw 15th edition page: 8.
Gynaecology & Obstetrics
null
25343dd1-4569-4074-8725-88011983a38d
'Marchiaa-Bignami' syndrome is
Also called hospital addiction
Related to alcoholism
Congenital
Related to opium withdrawal
1b
multi
It is a complication of alcoholism Marchiaa-Bignami disease is a progressive neurological disease characterized by corpus Callosum demyelination and necrosis and subsequent atrophy. Ref - Harrison 20th edition pg3112
Medicine
All India exam
329edf54-1279-45d3-863f-625cb64001aa
An 81-year-old female falls and presents to the emergency department. What injury to this tissue or structure causes lower leg extremities to be externally rotated?
Sacroiliac joint
Neck of femur
Lateral meniscus
Intertrochanteric
2c
multi
Both subcapital and intertrochanteric fractures present with external rotation of the lower extremity. The lateral rotators are attached to the bone distal to the fracture line to cause this typical clinical sign. Trochanteric fractures have a better prognosis because the blood supply to the proximal segment remains in...
Surgery
Trauma
6555d05a-081c-4e90-b801-61bb89c95cec
Reinke's layer seen in:
Vocal cord
Tympanic membrane
Cochlea
Reissner's membrane
0a
single
Reinke's edema is the build-up of a gelatinous substance in the layer right underneath the surface lining of the vocal folds (superficial lamina propria orReinke's space). It may occur in one or both vocal folds. The superficial lamina propria, or Reinke's space, is not an empty space.
ENT
null
9f9b323d-577d-410b-b1c5-1e72d4541a43
'Row of tombstones' appearance is seen in :
Irritant dermatitis
Pemphigus
Pemphigoid
Harpes zoster
1b
single
B. i.e. Pemphigus
Skin
null
54aefb9f-0060-4922-86d5-4e9e65fdfbea
The absolute indications for dialysis include the following except -
Persistent Hyperkalaemia
Congestive cardiac failure
Pulmonary edema
Hyperphosphatemia
3d
multi
Answer- D. HyperphosphatemiaPericarditis or pleuritis (urgent indication).Progressive uremic encephalopathy or neuropathyPersistent metabolic disturbancesFluid overload refractory to diuretics.Hypeension poorly responsive to antihypeensive medications.Persistent nausea and vomiting.
Medicine
null
edde6c70-edc4-41f9-bd2a-c96a2a2397b1
Apocrine mode of secretion is classically seen in _______ glands?
Mammary
Sebaceous
Parotid
Meibomian gland
0a
multi
Apocrine mode of secretion is seen in Mammary gland Modes of Secretion of exocrine glands can be classified as - Merocrine Apocrine Holocrine
Dental
Disorders of sebaceous and sweat glands
9cfaf46e-8735-4c37-8570-d127e17812aa
CongenitalA-V fistulas in the thigh will be associated with all except -
Increased cardiac output
Increased skin temperature
Gigantism of limb
Superficial venous engorgement
1b
multi
Ans. is 'b' i.e., Increased skin temperature
Surgery
null
a4b1e523-853a-405f-9935-d9abd23dc1ea
Treatment of Acute lymphangitis requires ?
Antibiotic and rest
Immediate lymphangiography
Immediate multiple incisions
No special treatment
0a
single
Ans. is 'a' i.e., Antibiotic and rest
Surgery
null
afb2ec17-ea70-4bed-b791-3edb0d5e7579
Gastric tetany is due to -
Increased intestinal acidity
Vagal Hyperactivity
Increased Calcium Sequestration
Decreased Calcium absorption
3d
single
Ans. is 'd' i.e., Decreased Calcium absorption I could not find the answer but here is what I know Gastric tetanv is tetany due to disorders of stomach, especially with loss of HC1 by vomiting.
Surgery
null
3965fdc8-7a09-4ffe-88d2-88bd402e63e5
Breast Ca is not a/w -
BRCA 1 & BRCA 2
Apocrine metaplasia
Atypical ductal hyperplasia
All
1b
multi
Ans. is 'b' i.e., Apocrine metaplasiao Apocrine metaplasia and fibroadenoma (without atypical features) do not increase the risk of breast cancer.o Atypical epithelial hyperplasia moderately increases the risk and moderate to florid epithelial hyperplasia slightlyincreases the risk for breast carcinoma.o Mutations in B...
Pathology
null
70db1adc-1b39-4f5a-a757-0815dbff2df2
Rapid Reduction of blood pressure is indicated in :
Acute Aoic Dissection
Hypeensive Encephalopathy
Intracercbral haemorrhage
All of the above
3d
multi
Answer is D (All of the above) Acute Aoic Dissection, Hypeensive Encephalopathy and Intracerbral haemorrhage are all hypeensive emergenices that require rapid reduction of blood pressure Indications for rapid reduction of BP Rapid reduction of blood pressure is indicated in hypeensive emergencies and hypeensive urgenci...
Medicine
null
c46e998b-1bb0-4452-a79a-e45eecec57a8
Fibrinogen degradation products help in detection of
DIC
Hemophilia
TTP
ITP
0a
single
DIC - Disseminated intravascular coagulation Multiple coagulation factors are consumed and are therefore deficient Plasminogen bound to platelet-fibrin thrombi is converted to plasmin by plasminogen activators Plasmin cleaves fibrinogen as well as fibrin to generate fibrin degradation products.
Pathology
null
809f995e-7ab5-4f85-9b8b-09c2e54fd982
Who propounded the germ theory of disease -
Leeuwenhoek
Robert koch
Ambroise Pare
Louis Pasteur
3d
single
Louis Pasteur (1822-1895) demonstrated by the presence of bacteria in the air, thereby disproving the theory of “spontaneous generation” and proposed “germ theory of disease”
Social & Preventive Medicine
null
8ab72111-a3e3-4d1b-8c0b-84169ef1ae1d
Which of the following will cause Lathyrism
Kesari dhal
Mung dhal
chana dhal
Udardhal
0a
single
Ans) a (Kesari dhal) Ret Park 20th Edn P 558, 559Toxic principle is Beta oxalyl amino alanirie the diet containing over 30% of this dhal if taken over a period of 2-6 month will result in neurolathyrism.The disease mainly affects young males and manifests itself in stages.Interventions* Vitamin C prophylaxis* Banning t...
Social & Preventive Medicine
Nutrition and Health
bb9f545c-d992-4fbf-8a46-413fb4db6b5c
TRUE statement about achalasia cardia is:
Achalasia is a common disorder
Loss of ganglion cells within the esophageal myenteric plexus
Excess LES relaxation is the major pathology
Latent infection with rubella virus is responsible for it
1b
multi
Achalasia is a rare disease It is caused by loss of the ganglion cells within the esophageal myenteric plexus With long-standing disease, viual aganglionosis is noted. Pathology: Impaired deglutitive LES relaxation and absent peristalsis. It is believed that cause of ganglion cell degeneration in achalasia is an autoim...
Medicine
null
d5a5b0d8-36da-48ea-8a01-c197d4652ffc
A 48-yrs-old male alcoholic with cirrhosis has bilateral gynecomastia. Which physical findings has the same pathogenesis as gynecomastia?
Caput medusae
Asterixis
Ascites
Spider angioma
3d
single
Gynecomastia in male cirrhotics is caused by hyperes­trinism secondaty to the inability of the liver to metab­olize estrogens. Hyperestrinism results in the develop­ment of female secondary sex characteristics, palmar erythema, spider angioma, and testicular atrophy caused by decreased testosterone.
Unknown
null
e6d3571a-d5e6-4daf-8949-fafb06981f51
Skin and facia of great toe drains into
Veical group of superficial inguinal lymph node
Horizontal group of superficial inguinal lymph node
Obturator lymph nodes
Deep inguinal lymph nodes
0a
single
The superficial inguinal lymph nodes form a chain immediately below the inguinal ligament. They lie deep to Camper&;s fascia which overlies the femoral vessels at medial aspect of the thigh. They are found in the triangle bounded by the inguinal ligament superiorly, the border of the saorius muscle laterally, and the a...
Anatomy
Lower limb
8775df43-990f-4483-a7c4-4a115796c2a3
Obesity in a child of age 2 years is defined as:
Weight for height more than double of expected
Weight for age more than double of expected
BMI >30
BMI >95th percentile
3d
single
d. BMI >95th percentile(Ref: Nelson's 20/e p 307-315, Ghai 8/e p 528-529)Obesity in children is defined as BMI >95th percentile; Body mass index (BMI) is equal to weight/height2 (in kg/m2).
Pediatrics
Endocrinology
208c1491-3637-4305-8944-226459887ef3
Propoion of area from middle of curve to +1 standard detion-
0.68
0.17
0.12
0.34
3d
single
Ref:Parks 23rd edition pg 849. 1SD : confidence limit = 68% 2SD : confidence limit = 95% 3SD : confidence limit = 99.7% +/- 1SD: includes 68% of values, so +1SD will include half of it = 34%
Social & Preventive Medicine
Biostatistics
fc4f7069-ccbb-4b83-9ae6-4ae512ed6eaf
Red keratic precipitates are seen in -
Granulomatous uveits
Hemorrhagic uveitis
Old healed uveitis
Acute anterior uveitis
1b
single
Red KPs: These are formed when in addition to inflammatory cells, RBCs also take pa in composition. They may be seen in haemorrhagic uveitis.
Ophthalmology
Uveal tract
c6748709-6298-4e73-853d-8b1fee7f991d
In right middle ear pathology, Weber's test will be:
Normal
Centralised
Lateralised to right side
Lateralised to left side
2c
single
In Weber's test, tuning fork is placed on the forehead or vertex in the midline. Sound is conducted equally to both ears through bone vibration. In a normal person, the sound is centralised as it is heard equally in both ears.In conductive deafness, sound is localised to the affected ear (in this case right ear) becaus...
ENT
Ear
802b2d8d-6422-48ab-8413-b6aa4af426c3
Which of the following statements about GLUT is false?
GLUT-2 is needed in brain
GLUT-3 is present in placenta
GLUT-4 is present in adipose tissue
GLUT-3 is present in both intestine and testis
0a
multi
GluT2 present in the serosal surface of intestinal cells, liver, beta cells of the pancreas. GluT3 present in neurons, and brainRef: DM Vasudevan, 7th edition, page no: 106
Biochemistry
Metabolism of carbohydrate
4e0bffa5-ef60-4b1b-9755-389e4e93809c
Nerve supply to musculature of urinary bladder is ?
Symphathetic
Parasympathetic
Both
None
2c
multi
Ans. is 'c' i.e., BothParasympathetic supply is motor to detrusor muscle and inhibitory to sphinchter vesicae. Sympathetic supply is motor to sphincter vesicae and inhibitory to detrusor muscle.Nerve supply of bladderBladder is supplied by both sympathetic and parasympathetic fibers.Parasympathetic : Preganglionic fibe...
Anatomy
null
681ba8a4-9b92-47f2-8820-efb59a6c9ced
A 45-year-old chronic alcoholic male is brought to the emergency department with an alleged history of assaulting his neighbor. On examination, he is found to have irrelevant talk. He had not consumed alcohol for the past 4 days. He is diagnosed as a case of delirium tremens. In this condition, the person is:
Criminally responsible for his act
Partially responsible for his act
Has diminished responsibility of his act
Not responsible for his act under section 84, IPC
3d
multi
Ans. d. Not responsible for his act tinder section 84, IPC (Ref: Reddy 33/e p493, 29/e p432)"Delirium tremens is a severe form of alcohol withdrawal that involves sudden and severe mental or nervous system changes. It is considered as unsoundness of mind and not of intoxication. Thus if delirium tremens can be proved, ...
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
a04e1a1f-4c4c-493d-b153-82313b5addd7
Loss of hetrozygosity associated with ?
Acute myeloid leukemia
ALL
Retinoblastoma
Promyelocitic leukemia
2c
multi
Ans. is 'c' i.e., Retinoblastoma Retinoblastoma is a prime example of a tumour which is associated with loss of heterozygosity. This term is mostly used in the context of oncogenesis. o The mutations required to produce retinoblastomes involves the RB gene located on chromosome 13 q14. o RB gene is a tumour suppressor ...
Pathology
null
5a02ed5c-f452-4fd5-82f5-b775f2b3ab9a
A 40-year female has to undergo incisional surgery under general anesthesia. She complains of awaken during her past cesarean section. Which of the following monitoring techniques can be used to prevent such awareness?
Color Doppler
Bispectral index monitoring
Transesophageal echocardiography
Pulse plethysmography
1b
single
Ans. b. Bispectral index monitoring (Ref: Morgan 4/144-146; Lee's 12/e p146, 286, 447)Use of the bispectral index (BIS), developed front a processed electroencephalogram, has been reported to decrease the incidence of anesthesia awareness when the BIS value is maintained below 60.Bispectral Index Scale (BIS)It is based...
Anaesthesia
Miscellaneous General Anesthesia
42e9a245-8a62-42b4-9bc1-4c3bf7f5b64b
The kebab treatment is used for treatment of which of the following conditions
Paget's disease
Osteoahritis
Myositis ossificans
Osteogenesis imperfecta
3d
single
Osteogenesis imperfecta is characterized by multiple fractures and multiple deformities and one of the surgical treatment devised is the kebab treatment which consists of multiple osteotomies and threading of the multiple fragments over an intramedullary implant, thus a fanciful resemblance to the delicacy.
Pathology
All India exam
7011e887-803e-439e-9b20-37ea7dca95bd
A patient comes to hospital with a history of sore throat, diarrhea and sexual contact 2 weeks before. The best investigation to rule out HIV is -
p24 antigen assay
ELISA
Western blot
Lymph node biopsy
0a
single
The p24 antigen can be detected during window period, during which antibodies are not demonstrated in the serum. So, used for early detection. The p24 antigen appears within 2 weeks (average 16 days) after infection. So, it is the best investigation to rule out HIV among the options given above. Note: Nucleic acid test...
Microbiology
Virology Pa-2 (RNA Virus Pa-1,2 & Miscellaneous Viruses)
69b1b147-ad35-4899-bec8-ffd8b30c4e8f
Lesion in the optic chiasma causes
Bitemporal hemianopia
Upper nasal
Lower nasal
Upper temporal
0a
single
A i.e. Bitemporal hemianopia
Ophthalmology
null
8a82f9e4-b38f-43f6-9d8d-4ef8a6a4bcbf
40-year male patient who was a known smoker presents in AIIMS OPD with fever, latigue, jaundice, yellow colored urine with clay colored stools. For the past few days he had developed aversion to cigarette smoking. On examination scleral icterus was present. LFT are:Total Bill18.5Direct Bill7.5SGOT723SGPT812What investi...
HBsAg, IgM antiHBC, AntiHCV AntiHEV
AntiHAV, HBsAg, IgM antiHBc, AntiHCV
HBsAg, IgM antiHBC,AntiHDV AntiHCV AntiHEV
AntiHAV IgMantiHBC, AntiHCV, AntiHEV.
1b
single
Ans: B. AntiHAV, HBsAg, IgM antiHBc, AntiHCVRef: Harrison, I8't' ed., pg. 328, 2549-2552, 2550t, 2551tHB- sAgIgM Anti- HAVIgM Anti- HBcAnti-HCVDiagnostic Interpretation+ + Acute hepatitis B Chronic hepatitis B++ Acute hepatitis A superim? posed on chronic hepatitis B+++ Acute hepatitis A and B--+ Acute hepatitis A--++ ...
Medicine
null
9d63a551-761a-4db0-b8f5-fb9bfe7fe449
Parathormone increases calcium absorption by acting at ?
PCT
DCT
Loop of henle
Collecting duct
1b
single
Ans. is 'b' i.e., DCT ParatharmoneParatharmone is 84 aminoacid polypeptide hormone secreted from parathyroid glands.Its secretion is regulated by plasma Ca++ concentration -- fall in Ca++ concentration increases the secretion of paratharmone.ActionsPTH increases resorption of calcium from bone - most prominant action.P...
Physiology
null
e65fe6c0-a2e9-4267-812e-45f7ceb3b4b6
Not seen in serotonin withdrawal is?
Nausea
Irritability
Vivid dreams
Flushing
1b
single
Flushing REF: Harrison 17th ed t-e-35-4 "Flushing is seen in serotonin toxicity and not withdrawal" Serotonin withdrawal: Symptoms described as "brain zaps", "brain shocks", "brain shivers", "head shocks", or "cranial zings" are a withdrawal symptom experienced during discontinuation (or reduction of dose) of antidepre...
Surgery
null
ab5375ef-8f5d-4f38-8a8c-91c0da6ac2dc
In which of the following rigor mois is not seen?
Well built male
Well built female
Old patient> 80 years
Fetus <7 months
3d
single
Rigor mois is not seen in fetus less than 7 months. It develops slowly and is marked in healthy adults. It is feeble and rapid in infants. Dr. Narayana Reddys Synopsis of Forensic Medicine & Toxicology 27 th edition pg. 80.
Forensic Medicine
Death and postmortem changes
c122415e-cc6a-48cf-a112-0dc7369dca9d
Maximum absorption of short chain fatty acids produced by bacteria occurs in the
Colon
Duodenum
Jejunum
Ileum
0a
single
A. (Colon) (475. Ganong 22nd) / (458 - Ganong 23rd)Short-chain Fatty Acids in the colon (SCFAs) are produced in the colon and absorbed from it *** ** Absorption of long chain FA is greatest in the upper parts of the small intestine* Average normal concentration of about 80 mmol/ L in the lumen* About 60% of this total ...
Physiology
G.I.T.
0096fa6d-65d0-4de9-bbf7-57a73b0df7ba
According to 'Biomedical concept' health is?
Relative absence of pain and discomfo
Absence of disease
A sound mind in sound body, in a sound family, in sound environment
None
1b
multi
Ans. is 'b' i.e., Absence of disease
Social & Preventive Medicine
null
9f48500a-add3-4668-a297-3bb69833c8a1
Following gene when mutated, protects tumor cells from Apoptosis
BCL-2
BRCA
RB
TGF-b
0a
single
Ans. (a) BCL-2(Ref: Robbins 9th/pg 594-595)BCL2 antagonizes apoptosis and promotes survival of follicular lymphoma cells.BCL stands for 'B Cell Lymphoma'
Pathology
Misc. (W.B.C)
5a726423-4ba5-4d5d-8e8c-2e7d7ea1ce04
Method to represent qualitative data -
Histogram
Comulative frequency curve
Frequency polygon
Bar Chart
3d
single
Ans. is 'd' i.e., Bar Chart DataScaleGraph/DiagramQuantitativeInterval scale Ratio scaleHistogram Frequency polygon frequency curves line chart scatter diagram Cumulative frequency Curve Line Chart graphQualitativeNominal scale Ordinal scaleBar diagram Pie chart PictogramMap diagram or spot map
Social & Preventive Medicine
Data Variables
e744b2f1-a8d7-46ad-95d8-b8a357747e8b
A 15-year-old female presents with primary amenorrhea. Her breasts are Tanner 4 but she has no axillary or pubic hair. The most likely diagnosis is:
Turner's syndrome
Mullerian agenesis
Testicular feminization syndrome
Premature ovarian failure
2c
single
Ans. is c, i.e. Testicular feminization syndromeRef: Novak 14th/ed, p1037-1038When a female comes with complain of primary amenorrhea the first thing to do is see her secondary sexual characteristics:* In Turner's Syndrome all secondary sexual characteristics are absent where as in the question the female has proper br...
Gynaecology & Obstetrics
Sex Intersexuality
17946f81-1176-46f2-a290-6491c147abc8
Which of the following tumor causes polycythemia due to increased erythropoietin production?
Cerebellar hemangioblastoma
Medulloblastoma
Ependymoma
Oligodendroglioma
0a
single
Secondary erythrocytosis involves increased erythropoietin (EPO) signalling in the bone marrow. Several types of neoplasm are known to produce excess EPO, including renal cell carcinoma, uterine fibroids, hemangioblastoma, and hepatocellular carcinoma. EPO production can also be increased following renal transplant Ref...
Pathology
null
0ba29c66-1d9d-42f7-8b9e-c80710d430f5
What is false regarding dentate line:
Glands of Morgagni open below the line
Anal glands open at the line
Dentate line lies 2 cms above the anal verge
Transitional epithelium lies above the dentate line
3d
multi
D. i.e. Transitional epithelium lies above the dentate line
Anatomy
null
a8463c94-e7de-4e87-b3e2-b9c71d34a14f
Griffith experiment was done on ?
Streptococcus
Pneumococcus
Enterococcus
Staphylococcus
1b
single
Ans. is 'b' i.e., Pneumococcus In 1928, Frederick Griffith's experiment first demonstrated transformation in streptococcus pneumoniae.Frederick Griffith's experiment on pneumococcus (streptococcus pneumoniae) proved that genetic characters are transmitted from one generation to the other through transformation.
Microbiology
null
eb5772d5-41a2-40b1-973c-e31eddb16f88
Corynebacterium diphtheriae can be grown within 6-8 hour on
Potassiu, tellurite media with iron
McConkey's agar
Dorset egg medium
Loeffler's serum slope
3d
single
The usual media employed for the cultivation of diphtheria bacilli are Loeffler's serum slope and Tellurite blood agar. Loeffler's serum slope: Diphtheria bacilli grow on Loeffler's serum slope very rapidly and colonies can be seen in 6-8 hours, long before other bacteria grow. Colonies are first small, circular white ...
Microbiology
Bacteriology
c4488314-fa71-4f95-badd-13ecf7d3fdd3
Not a baby friendly hospital recommendation ?
Breast feeding with half-hour of bih
Breast feeding on demand
Use of aificial teats when required
No oral feed other than breast milk
2c
single
Ans. is 'c' i.e., Use of aificial teats when required Baby friendly hospital initiatives Baby friendly hospital initiative (BFHI) was launched for promotion, protection and suppo of breastfeeding. It was launched by WHO and UNICEF. BFHI has listed following ten steps, which the hospital must fulfill. Have a written bre...
Social & Preventive Medicine
null
63f483c7-82cf-472e-a85b-f619da9ed415
What is the COMMONEST cause of primary amenorrhea with ambiguous genitalia in a female with 46XX chromosome?
21 hydroxylase def
17 hydroxylase def
11 hydroxylase def
Desmolase hydrolase def
0a
single
21 hydroxylase deficiency is the most common cause of androgenization in chromosomal 46 XX females. In this condition there is a block in the synthesis of glucocoicoid and mineralocoicoid and increase in the level of 17 hydroxyprogesterone. Increased androgen synthesis in utero causes androgenization of the female fetu...
Physiology
null
61d7eb22-8729-4e4a-8523-e13c7559ff93
All of the following changes are seen in dysplasia of squamo-columnar junction, except :
Breaking of basement membrane
Change of epithelium
Hyperchromatic nuclei
Increased mitotic figure
0a
multi
Ans. is a i.e. Breaking of basement membrane Friends before discussing the answer to this question lets first have a look at some impoant terms and their meaning i. Cervical metaplasia :The cervix is composed of columnar epithelium which lines the Endocervix and squamous epithelium which covers the Ectocervix. The poin...
Gynaecology & Obstetrics
null
0df81e0b-355e-4585-82d4-f563f43d2988
Most common cause of unilateral proptosis in adults is -
Thyroid ophthalmopathy
Rhabdomyosarcoma
Orbital blow out fracture
Orbital cellulitis
0a
single
Ans. is a i.e., Thyroid ophthalmopathy * The most common cause of unilateral proptosis in children is orbital cellulitis* The most common cause of unilateral proptosis in adults is thyroid ophthalmopathy.* Most common cause of bilateral proptosis in children ->> Neuroblastoma (me), Leukemia (Chloroma)* Most common caus...
Ophthalmology
Orbit
62c16db5-644f-44fc-b389-11480a18dfa4
A method of strangulation of neck by the bend of elbow is called
Mugging
Garroting
Bansdola
Throttling
0a
multi
Refer the byte "Hanging and Strangulation".
Forensic Medicine
null
0391e13d-48ee-4b9e-b03b-dbe593e929e7
Muscles derived from visceral splanchnic lateral plate mesoderm is-
myoepitheliocytes of skin glands
iris muscles
smooth muscles of gut tube
detrusor
2c
single
Lateral plate mesoderm:- somatic mesoderm (dorsal) ventral visceral mesoderm SOMATIC MESODERM VISCERAL MESODERM parietal layers of pleura, peritoneum, pericardium visceral layers of pleura, peritoneum, pericardium visceral muscles- cardiac muscles of CV tube, smooth muscles of gut tube, respiratory tube EXCEPTIONS- myo...
Anatomy
General Embryology 2
5eaf4b28-096e-4e29-8d8f-e81bc46e456a
NADPH oxidase deficiency causes:
Chedickhigasi syndrome
Chronic granulomatous disease
Leucocyte adhesion defect type 1
Leucocyte adhesion defect type 2
1b
single
ANSWER: (B) Chronic granulomatous diseaseREF: Medical biochemistry at a glance J. G. Salway page 47, The Metabolic basis of inherited disease John Bruton Stanbury page 1971Chronic granulomatous disease is a rare, X-linked deficiency of NADPH oxidase activity which drastically impairs the ability of macrophages and neut...
Biochemistry
Miscellaneous (Bio-Chemistry)
dc8193fb-e33a-4a5d-ac28-8fa87b52401b
Which among the following is not a branch of Arch of Aorta?
Brachiocephalic
Right common carotid
Left common carotid
Left Subclavian
1b
single
ANSWER: (B) Right common carotidREF: Keith L. Moore 4th edition page 103The branches of the arch of the aorta are:Brachiocephalic trunk.Left common carotid artery.Left subclavian artery.The brachiocephalic trunk, the first and largest branch of the arch, arises posterior to the manubrium, where it lies anterior to the ...
Anatomy
Blood Vessels of Thorax
e3b5fcf8-7303-4b48-9382-a123cc4676e0
Not seen in cushing's syndrome: March 2009
Hypeension
Weight gain
Hirsutism
Hypoglycemia
3d
single
Ans. D: Hypoglycemia Symptoms of Cushing's syndrome include rapid weight gain, paicularly of the trunk and face with sparing of the limbs (central obesity). A common sign is the growth of fat pads along the collar bone and on the back of the neck (buffalo hump) and a round face often referred to as a "moon face". Other...
Medicine
null
d26e15bd-2d51-4211-9fa5-bb591a1c4a5d
If a 95% confidence Interval for prevalence of cancer smokers aged > 65 years is 56% to 76%, the chance that the prevalance could be less than 56% is ?
Nil
44%
2.50%
5%
2c
single
Ans. is 'c' i.e., 2.5% In this questions: 56 to 76 confidence interval covers 95% (2SD) of values. That means 5% of values will fall outside the range of 56-76 --4 2.5% values will be below 56 and 2.5% values will be above 76.
Social & Preventive Medicine
null
1d3d342b-c8c8-4b75-9188-a13c5d0165ea
Minimal reabsorption from kidney is of -
Na+
Glucose
HCO3-
Urea
3d
single
Ans. is 'd' i.e., Urea Renal handling of various plasma constrituents in a normal adult human on an average diet. Per 24 Hours SubstanceFitteredReabsorbedSecretedExcretedPercentage ReabsorbedNa+ (mEq)26,00025,850 15099.4K+(mEq)600560a5029093.3C1- (mEq)18,00017,850 15099.2HCO3-mEq)4,9004,900 0100Urea (mmol)870460 b 4105...
Physiology
Renal Tubular Reabsorption and Secretion
2605967e-d4d7-465c-964d-68bda01ebfaa
Prerenal and renal azotemia is differentiated on the basis of:
Creatinine clearance
Serum creatinine level
Sodium fraction excretion
Urine bicarbonate level
2c
single
Answer is C (Sodium Fraction Excretion):
Medicine
null
da593547-dcce-4f8d-9517-9cfbb34f20c3
Primary Membranous Nephropathy has antibodies against ?
Phospholipase Al receptor
Phospholipase A2 receptor
Phospholipase A3 receptor
Phospholipase A4 receptor
1b
single
Ans. is 'b' i.e., Phospholipase A2 receptorPrimary Membranous NephropathyPrimary (also called idiopathic) membranous nephropathy is considered to be an autoimmune disease linked to ceain HLA alleles such as HLA-DQA1 and caused in most cases by antibodies to a renal autoantigen.In many adult cases the autoantigen is the...
Pathology
null
78321c6d-8d6f-458e-ba35-fabf54a20e05
Which of the following should be considered as the cause of generalized convulsions 20 minutes postoperatively?
Halothane
Enflurane
Isoflurance
Sevoflurane
1b
single
Enflurane can precipitate seizures in epileptic patients and hence is usually avoided in them. Whereas the rest of the given drugs do not provoke seizures. From padmaja 4th edition Page no 190,191
Pharmacology
Anesthesia
da845024-bc4b-4c3f-b874-db4c4d0790e1
False about acute tubular necrosis
BUN/Creat>20
Una > 40
FeNa > 2%
Ucr/Pcr<40
0a
multi
BUN/Creat  < 20 in ATN. BUN/Creat  > 20 in pre-renal failure.
Medicine
null
59ae6373-0497-4761-994f-1cd60fc5503c
Cyclic GMP act on :
Insulin
Thyroxin
Atrial natriuretic peptide
Growth harmone
2c
single
C i.e. Atrial natriuretic peptide
Physiology
null
e969f78d-9c58-47a6-86f8-9939c855aa2f
A patient with dermatomyositis repos improvement of symptoms on steroids for last 6 months. Labs did today show Creatine kinase of 1300 Units/L. What is the next step in the management?
Continue the same dose of steroids
Raise dose of steroids
Sta mycophenolate
Perform muscle biopsy
0a
multi
The main objective of treatment in dermatomyositis is to improve muscle strength and reduce extra-muscular symptoms. Serum CK levels are monitored however dose adjustment of Steroids and other immuno-therapies are primarily based on the clinical examination and not CK levels. When no response is noted after adequate ph...
Medicine
Channelopathies and Neuropathies