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9fa6b487-0676-4dd9-8fc8-5048634216e9 | The lower angle of scapula lies at the level of? | T5 | T6 | T7 | T8 | 2c | single | The root of the spine of the scapula is on a level with the tip of the spinous process of the third thoracic veebra, and the inferior angle with that of the seventh. Landmarks and internal structures found at various veebral levels. Thoracic Veebral LevelLandmarkInternal SignificanceT1Sternoclavicular jointHighest poin... | Anatomy | null |
119054fe-881d-45a5-8adb-ce09128ca903 | Carcinoma breast spread to other breast is more common in which of the Carcinoma breast: | Lobular carcinoma | Scirrhous Carcinoma | Both of the above | None of the above | 0a | multi | Invasive lobular carcinoma accounts for 10% of breast cancers. LCIS(LOBULAR CARCINOMA IN SITU) originates from the terminal duct lobular units and develops only in the female breast. It is characterized by distention and distoion of the terminal duct lobular units by cancer cells, which are large but maintain a normal ... | Surgery | null |
317dc19e-ae9b-4d18-8c77-31171ff78dbc | Drug of Choice for absence seizure in children < 3 years of age is | Ethosuximide | Carbamazepine | Lamtrigine | Phenytain | 0a | single | Answer- A. EthosuximideEthosuximide is the DOC for absence seizures in children below 3 years of age as Na valproate may cause fulminant hepatitis in children below 3 years of age. Broadly. Na valproate is the DOC for absence seizures. | Medicine | null |
fff46d71-cb03-48bf-af76-5643ae527467 | When capillary and interstitial hydrostatic pressures are 30 mm of Hg and 5 mm of Hg and colloid oncotic pressure of capillaries and interstitum if 25 mm of Hg and 5 mm of Hg, what is the Net filtration pressure? | 5 mm Hg | 10 mm Hg | 15 mm Hg | 20 mm Hg | 0a | single | Forces that our filtration - capillary hydrostatic pressure & plasma colloid oncotic pressure. Forces that opposes filtration - interstitial hydrostatic pressures & capillary oncotic pressure. Net filtration pressure -sum of hydrostatic & colloid osmotic forces that either our or oppose filtration across capillaries. T... | Physiology | JIPMER 2017 |
d5842784-949f-45db-b0b8-33dbfd3fee9f | A patient is admitted with 3rd episode of deep venous thrombosis. There is no history of any associated medial illness. All of the following investigations are required for establishing the diagnosis except | Antibodies to factor VIII | Antibodies to cardiolipin | Antithrombin II deficiency | Protein C deficiency | 0a | multi | It is a cqpillary vascular malformation also called as naevus simplex. Commonly seen in 40% of new borns. It is present at bih,usually involves nape of neck,face,scalp,limbs. With age,it goes for spontaneous regression and disappears completely,usually in one year. | Surgery | Vascular surgery |
29ea452b-ca7a-4a9f-9651-63dc65859cde | IL-2 is produced by: | T cells | B cells | Monocytes | Neutrophils | 0a | single | Answer is A (T cells) : IL-2 is produced by T helper cells (CD4 cells). Its actions include: Promotes growth and differentiation of T and B cells: interestingly, receptors for IL-2 are present on T cells themselves, and so the secreted IL-2 acts on these very receptors and promotes growth & differentiation of T cells. ... | Medicine | null |
acced176-0fe1-403b-b526-ccf9a9b5c482 | Following condition is caused by: | Treponema | HSV 2 | Small Pox virus | Syphilis | 1b | multi | Genital herpes - Infection of the genitals caused by HSV. Either have no or mild symptoms. Blisters break open to form painful ulcers. Flu-like symptoms, such as fever, aching, or swollen lymph nodes. Onset is within 4 days after exposure with symptoms lasting up to 4 weeks. Antiviral medications, such as acyclovir, va... | Dental | Sexually Transmitted Infections |
5533d652-5bc9-469f-9548-7ba4298ecb01 | Proteins in nucleosome are made up of - | Histidine | Asparagine | Aspartate | Glutamate | 0a | single | Ans. is 'a' i.e., Histidine* Histones are positively charged by virtue of their composition. They are made up of positively charged or basic aminoacids - Histidine and Arginine* Human chromosome when fully extended will measure a few metres long* Such a long chromosome is packed inside a nucleus of few microns in diame... | Biochemistry | Molecular Genetics |
81d61a2d-8dcc-4b3c-8c01-ad249160e09a | Which method is used for destroying useless hospital waste products? | Hot air oven | Incineration | Autoclave | Heat sterilization | 1b | single | Ans: b (Incineration) Ref: Ananthanarayan, 7th ed, p. 25; Park, 18th ed, p. 599Incineration is an excellent method of safely destroying materials such as contaminated cloth, animal carcasses and pathological materials.Categorization of biomedical waste and its disposal:Cat IHuman anatomical wasteIncinerationCat IIAnima... | Microbiology | General |
fc83df2a-e58c-4bb9-b4e8-d20541d3f9c4 | The prevalence of disease in a population is expected to be 50%. An investigator is interested in the range of 45 to 55% with 95% confidence. The minimum sample size required for the study is: | 100 | 200 | 300 | 400 | 3d | single | Answer- D (400)In this question, use Standard Error of propoions.The 95% confidence limits for a propoion are p +- 1.96 s.e.p, where s.e.p is the standard error of a propoion.p = sample propoion = propoion of diseased persons = 0.5 q = 1-p = 0.5 s.e.p .NI(p x q / n) Now here, the range of propoions with 95% confidence ... | Social & Preventive Medicine | null |
e950f219-9481-4278-9599-877db0d1544e | All are true about epidemiological features of cholera except ? | Epidemic is self limiting | Poor sanitation is a cause of epidemic | El Tor biotype has decreased endemicity | Onset of epidemic is abrupt | 2c | multi | The El Tor biotypes have greater endemic tendency than its classical counterpa in that it causes a higher infection-to-case ratio (i.e. more inapparent infections and mild cases). About other options Cholera epidemic has an abrupt onset. It stas as common source epidemic and often treat an acute health problem. Then it... | Social & Preventive Medicine | null |
cabe5655-284d-4c9d-9eb1-5fc79b08dbb7 | Which one of the following is NOT an epithelial tumour of the ovary: September 2012 | Serous cystadenoma | Brenner tumour | Clear cell tumour | Endodermal sinus tumour | 3d | single | Ans. D i.e. Endodermal sinus tumour Endodermal sinus (yolk sac) tumour is a rare tumour but the second most common of germ cell origin | Gynaecology & Obstetrics | null |
3c55835a-0901-45c8-8712-413be4c613de | All are true about DNA methylation except: | It usually occurs in the cytosine | Can alters the gene expression pattern in cells | Role in genomic imprinting | No role in carcinogenesis | 3d | multi | Ans: (D) No role in carcinogenesisCytosine in the sequence CG of DNA gets methylated to form 5'-methylcytosine. A major poion of CG (about 20%) in human DNA exists in methylated form.In DNA, methylation usually occurs in the CpG islands, a CG rich region, upstream of the promoter region. In humans, DNA methylation is c... | Biochemistry | null |
a5044d26-6c5b-40fd-a1f2-8f0351f35e1a | Ramsay Hunt syndrome is caused by: | H. simplex | H. zoster | Influenza | HIV | 1b | single | (b) H. zoster(Ref. Cummings, 6th ed., 2622)Herpes Zoster of external ear with facial palsy is known as Ramsay Hunt syndrome.H. simplex is being reported to be associated with Bell's palsy.Facial nerve palsy can also be caused by other viruses, for example HIV, influenza, polio, EBV, etc. | ENT | Facial Nerve And Its Disorders |
e22676e3-ebf4-464b-8af3-ab81a4f2e4b2 | Which one of the following clinical findings excludes the diagnosis of polymyositis? | Neck muscle involvement | Extraocular muscle involvement | Dysphagia | Abdominal muscle involvement | 1b | single | PM don't have any of the following:rashes ,involvement of extraocular and facial muscles ,family history of neuromuscular disease,history of exposure to myotonic drugs or toxins ,endocrinopathy ,neurogenic disease,muscular dystrophy ,biochemical muscle disorder. Ocular muscles are never involved in generalized polymyos... | Medicine | C.N.S |
a832aaf7-91a0-421e-ba63-0a977d5d0d4b | All are true about cluster sampling except ? | Sample size is same as that of simple random sampling | It is a two stage sampling | It is cheapter than other methods of sampling | It has a disadvantage of higher sampling error | 0a | multi | Ans. is 'a' i.e., Sample size is same as that of simple random sampling o Cluster sampling is an example of "two-stage sampling" or "mulistage sampling" - i) In first stage a sample or areas is chosen In the second stage a sample of respondent within those areas is selected. o Cluster sampling generally increases the v... | Social & Preventive Medicine | null |
0b02c7c1-9590-4466-bfea-75a3e8a07f81 | A 20 year old male presents with extrapyramidal symptoms and liver damage. Diagnosis | Wilson's disease | Huntington's disease | Parkinsons's disease | Hemochromatosis | 0a | single | Wilson's disease It is characterized by excessive deposition of copper in the liver, brain and other tissues Clinical features Liver disease during first decade of life or with neuropsychiatric illness during 3rd decade Kayser-Fleischer ring - due to deposition of copper in Descemet's membrane in the limbs of corners R... | Anatomy | G.I.T |
c281e5fa-ce51-4f13-9f4b-0543d8552a6f | Mesangial deposition of electron dense substance seen in? | IgA nephropathy | Membranous nephropathy | Minimal change disease | Post streptococcal glomerulonephritis | 0a | single | Ans. is 'a' i.e., IgA nephropathyIgA Nephropathy: shows presence of electron dense deposits in the mesangium. | Pathology | null |
a02325df-f7f3-43ee-bc9f-e50503e74938 | Which of the following is physiological uncoupler? | Thermogenin | 2, 4 nitrophenol | 2, 4 Dinitrophanal | Oligomycin | 0a | single | Physiological uncouplers i. Thyroxine, in high doses ii. Thermogenin in brown adipose tissueRef: DM Vasudevan Textbook of Medical Biochemistry, 6th edition, page no: 234 | Biochemistry | Respiratory chain |
b6a96562-ddcf-47da-bc81-fc18a7933fb5 | Which of the following is used as an antidote to nicotine poisoning | Neostigmine | Atropine | Phentolamine | Trimethaphan | 3d | single | Ref: HL Sharma 3rd ed pg:195 Nicotine is an agonist for NN receptors Ganglion blockers are antagonists for NN receptors eg: hexamethonium, trimethaphan, Mecamylamine etc | Pharmacology | Autonomic nervous system |
40d73166-800e-4cc7-9366-441c86a45b41 | According to the latest guidelines of vaccination, which of the following is applicable at the age of 5 years :- | DT Booster + Vitamin A | DT | DPT + OPV | DPT booster + Vitamin A | 3d | single | According to Latest National immunization Schedule - NIS 2020-21: - Total 3 doses of DPT vaccine each at 6,10 & 14 weeks; & 2 booster doses each at & 5yrs of age are given respectively. - Vitamin A should be staed at 9months of age & given for every 6months till 5yrs of age. - Hence DPT booster & Vit A are applicable a... | Social & Preventive Medicine | National Immunization Schedule 2020-21 |
5c2d4711-a8a9-494b-8c16-3f0932e1588b | Soft water has hardness levels of - | <50 | 100 | 150 | >200 | 0a | single | Level of hardness is expressed in terms of milliequivalents per litre where one milliequivalent is equal to 50mg calcium carbonate in one litre of water. The level of hardness of hard water is equal to 3-6mEq/L or 150-300 mg/L. CLASSIFICATION LEVEL OF HARDNESS (mEq./L) LEVEL OF HARDNESS (mg/L) soft water <1 <50 moderat... | Social & Preventive Medicine | Environment and health |
60fb0cdc-63d4-49fe-892a-a193bb5982e5 | The surface marking of the arch of aoa is as follows | Behind the manubrium sterni | 2nd intercostal space | 3rd intercostal space | Left 2nd costal cailage | 0a | single | ARCH OF AOA It lies behind the lower half of the manubrium sterni.Its upper convex border is marked by a line which begins at the right end of the sternal angle,arches upwards and to the left through the centre of the manubrium and ends at the sternal end of the left second costal cailage.Note that the beginning and en... | Anatomy | Thorax |
a399dec9-8d88-48ed-a9b9-c98c7d52f209 | Intrinsic causes of hemolytic anemia are all except | GCPD deficiency | Hereditary spherocytosis | Hypersplenism | Pyruvate kinase deficiency | 2c | multi | Hypersplenism is an extracorpuscular cause of heamolytic anemia. All other options are intracorpus cular / intrinsic causes of heamolytic anemia. | Pathology | null |
1c30645f-b97c-4f13-bccb-2b66c6dc0d97 | Birbeck granules are present in | Merkel cells | Langerhans cells | Langhans cells | Melanocytes | 1b | single | Ref Robbins 9/e p662 Birbeck granules, also known as Birbeck bodies, are rod shaped or "tennis-racket" cytoplasmic organelles with a central linear density and a striated appearance. First described in 1961 (where they were simply termed "characteristic granules"), they are solely found in Langerhans cells. | Anatomy | General anatomy |
c34ffe33-7feb-42de-a781-639642d8ab59 | Not a tumor marker | Tartarate resistant alkaline phosphatase | CEA | AFP | Alpha-1 antitrypsin | 3d | single | Ans. d (Alpha-1 antitrypsin). (Ref. Robbins, Pathologic Basis of Disease, 6th/pg.325) Alpha-1 Antitrypsin Blood Levels as Indicator for the Efficacy of Cancer Treatment Ref- Our data came to confirm this suggestion and to strongly conclude that the measurement of a1-AT blood levels during the course of cancer treatment... | Unknown | null |
2bb5625e-d6dc-479e-8a84-29a05f69b24d | The rash which is not central in predisposition is: | Epidemic typhus | Measles | Secondary syphilis | Typhoid | 2c | single | Centripetal rash (Primarily central/truncal) Mnemonic: "Red Rashes Scare Parents Very Much" Centrifugal rash (Primarily on extremities) Mnemonic: You drive CARS with your Hands and Feet Rubella CA - Coxsackie A Virus (Hand, Foot, Mouth disease) Roseola R-Rocky Mountain spotted fever Scarlet fever S-Secondary syphilis P... | Dental | Viral infections |
fc217272-cd6a-4ca7-a37a-ee233eb36a2d | Uronic acid level in urine is elevated in- | Tyrosinosis | Maple syrup urine disease | Nieman picks disease | mucopolysaccharidosis | 3d | single | Uronic acid (glucuronic acid) is one of the essential components of mucopolysaccharide (glycosaminoglycans). So, it is increased in mucopolysaccharidosis.
In mucopolysaccharidosis, glucuronic acid and iduronic acid are excreted in urine. | Biochemistry | null |
bec20479-ded9-4b55-8092-75b483c12ee2 | The muscle which makes an angle of about 51deg with the optical axis is | Superior oblique | Superior rectus | Inferior rectus | Lateral rectus | 0a | single | The extraocular muscles rotate the eyeball around veical, horizontal and antero-posterior axes. Medial and lateral rectus muscles are almost parallel to the optical axis of the eyeball; so they have got only the main action. While superior and inferior rectus muscles make an angle of 23deg and reflected tendons of the ... | Ophthalmology | Ocular motility and squint |
b93c40bb-b87e-4eb8-9780-a7a82944491b | The expectant line of management in placenta prae is contraindicated in | Pre term foetus | Live foetus | Breech presentation | Active labour | 3d | single | Active InterferenceThe indication of active treatment in placenta pre are: Bleeding is continuingBaby is dead or known to be congenitally deformed Bleeding occurs at or beyond 38 weeks of pregnancy Patients is in emarginated state on admissionPatient is labour. | Gynaecology & Obstetrics | General obstetrics |
80410736-345d-4285-842e-4779ea5a3728 | Perforins are produced by - | Cytotoxic T cells | Suppressor T cells | Memory helper T cells | Plasma cells | 0a | single | A protein found in the cytoplasmic granules of both T-cytotoxic lymphocytes and natural killer cells Reff: Ananthanarayan & Panikers textbook of microbiology 9th edition pg: 137 | Microbiology | Immunology |
895b0a22-7c6c-4abc-9bc9-29f257185b1f | In rectus sheath which branch of aoa make anastmosis with superior epigastric aery | Subclan aery | External iliac aery | Internal iliac aery | External carotid A | 1b | single | The external iliac aeries are two major aeries which bifurcate off the common iliac aeries anterior to the sacroiliac joint of the pelvis. They proceed anterior and inferior along the medial border of the psoas major muscles. They exit the pelvic girdle posterior and inferior to the inguinal ligament about one third la... | Anatomy | Abdomen and pelvis |
611bd245-e86d-4a2c-b23b-bdfda797043d | A drug X is secreted through renal tubles,tubular secretion of this drug can be confirmed if renal cleraclea of drug X is | More than the GFR | Equals to the GFR | Less than the GFR | More than volume of distrubtion | 0a | single | Ref-KDT 6/e p30 Atter filtration from glomerulus, a drug may undergo two processes (tubular reabsorption and tubular secretion) before going out from the body i.e renal clearance. Suppose 100 mg of a drug is filtered by glomerulus and the ren clearance is 150mg,it mean 50mg is coming from somewhere else, i.e. tubular s... | Anatomy | Other topics and Adverse effects |
589d2a09-343a-4bcc-be7a-7f21180ff398 | Manifestation of nephritic syndrome is- | Syphilis | Hypotension | Hematuria | Plyuria | 2c | single | In acute nephritic syndrome, 1-2g/24 hr of proteinuria. Hematuria with rbc casts pyuria hypeension, fluid retention Rise in serum creatinine associated with reduction in GFR. Ref:Harrison 20 th edition pg no 2134. | Medicine | Kidney |
193b42a5-b08b-4c48-8958-ca2aaa52485f | Not true about Fosphenytoin | Used for GTCS | Prodrug of Phenytoin | Lipid soluble | Highly protein bound | 2c | multi | Fosphenytoin, a more soluble phosphate prodrug of phenytoin, is well absorbed. Fosphenytoin sodium is available for intravenous or intramuscular use and replaces intravenous phenytoin sodium, a much less soluble form of the drug. Used in generalized Tonic-clonic seizures and paial seizures. Highly bound to plasma prote... | Pharmacology | Central Nervous system |
0e98c3a6-c4dc-430f-8a5c-a9d0c7d8da76 | A 14 year old male was presented to the casualty on a saturday night with left sided upper abdominal pain. Clinical examination revealed massive splenomegaly. He has history of massive hematemesis 2 year back, and was diagnosed to have Extrahepatic Poal Venous Obstruction (EHPVO) and bleeding was controlled by ligation... | Acute pancreatitis | Aoic dissection | Splenic infarction | Intussusception | 2c | single | EHPVO is a common cause of poal hypeension in children. It commonly presents with stable massive variceal bleeding during childhood. Patients have massive splenomegaly. Splenic infarction and mesenteric vein thrombosis are the two possibilities if EHPVO develops sudden onset of abdominal pain. Here we have splenic infa... | Medicine | null |
34d46769-dea9-4050-8bbf-78d84276ffea | In future replacement of questionable mandibular teeth is anticipated, the major connector of choice is: | Lingual bar. | Lingual plate. | Sublingual bar. | Sublingual plate. | 1b | single | When one or more incisor teeth have to be replaced in the future, the lingual plate is preferred because additional teeth can be added by attaching retention loops to it. | Dental | null |
a8a6a579-d0ad-4a83-b41f-73815ca025e0 | Contributory negligence is by the pa of: | Doctor | Patient | Both of the above | Paramedics | 2c | multi | Contributory negligence is defined as a concurrent negligence by the patient and doctor resulting in delayed recovery or harm to the patient. The negligence of both paies has contributed to this harm. Contributory negligence is good defense for the physician in civil cases but not in criminal cases. | Forensic Medicine | null |
2c3adf10-2bb9-4f73-a3f7-963a05a2267c | Which of the following fracture is known for Malunion ? | Femur neck | Supracondylar Humerus | Scaphoid | Lateral condyle of humerus | 1b | single | SCFH is known for malunion- gun stock defrmity. other fractures complication is non union. | Orthopaedics | Upper Limb Traumatology |
c7698d98-4ea2-4527-aa11-d3af40295b40 | Subdural haematoma most commonly results from | Rupture of intracranial aneurysm | Rupture of cerebral AVM | Injury to coical bridging veins | Hemophilia | 2c | single | C i.e. Rupture of coical bridging veins | Radiology | null |
9bc097d7-1b9e-4e6c-a3ae-5f9c7c556bca | Parkinsonism is characterised by all of the following characteristic features except : | Rigidity | Akinesia | Tremors at rest | Past pointing | 3d | multi | Answer is D (Past pointing): Past pointing is a feature of 'Cerebellar disease'. It is not seen in an extrapyramidal syndrome. Other features mentioned are all true for Parkinsonism. | Medicine | null |
6c27bb46-4947-416a-81eb-7099918af748 | Estradiol is a powerful inhibitor of FSH (follicle stimulating hormone). What is another factor that is a powerful inhibitor of FSH in the female? | Testosterone | Progesterone | LH | Inhibin | 3d | single | Inhibin, as its name implies, is an inhibitor. The specific action of inhibin is to inhibit the release of FSH. Inhibin occurs as a heterodimer It is produced in the male and the female. Inhibin is produced by the ovarian granulosa cells to prevent more than one follicle (in general) from becoming a mature follicle. Th... | Physiology | null |
0b214d33-6177-40b8-9044-59c2ccdbd0ea | Following resection of 2/3rd of the liver, regeneration is complete within | 2-3 months | 8-10weeks | 4-6 months | 4-5 weeks | 2c | single | Following resection of 2/3rd of liver, regeneration is complete within 5-6 months | Anatomy | G.I.T |
56dfafcc-6dcf-475c-80be-fd226e6238cf | A newborn with Down syndrome has constipation. Rectal examination shows no stool in the rectal ampulla. The proximal rectosigmoid is dilated on radiograph. The mechanism most likely responsible for the patient's disease is | An imperforate anus | An inflammatory lesion in the rectosigmoid area | Inspissated meconium owing to a defect in exocrine secretions | Absent ganglion cells in the submucosal and myenteric plexus | 3d | single | Down syndrome patients have an increased incidence of Hirschsprung disease (10% of all cases), which commonly presents with inability to pass meconium after 24 hours. * Hirschsprung disease, or congenital megacolon, is a deficiency of ganglion cells in Meissner submucosal plexus and Auerbach myenteric plexus, which cau... | Surgery | null |
0880cc30-1133-4c54-b950-eb4b6f0a136c | Transfer factor is an example of: | Artificial active immunity | Natural active immunity | Adoptive immunity | Artificial passive immunity | 2c | single | Acquired by injection of immunologically competent T-lymphocytes known as Transfer factor
Used for treatment when the CMI is low, e.g. Lepromatous leprosy. | Microbiology | null |
498663c2-362c-46c8-aa28-096b1b5dd33e | Gartner's duct cyst is seen in: | Vagina | Cervix | Hymen | Labia minora | 0a | single | Ans. A. VaginaThe most Gammon type of vaginal cysts is Gartner's duct Cyst. These cysts arise from the caudal remnants of the mesonephric or Wolffian duct system. They are usually located along the anterolateral aspect of the vaginal walls and are frequently bilateral.Gartner's ducts are remnants of the mesonephric (Wo... | Gynaecology & Obstetrics | Obstetrical Anatomy |
d035418a-f5af-4fc5-b25c-2c642f85da35 | Ureters are identified during surgery by - | Peristalsis d/t flow of urine | Rich arterial plexus | Relation to renal vein & artery | Relation to lumbar plexus | 0a | single | Ureters are muscular ducts situated retroperitoneally and are identified by peristalsis. | Anatomy | null |
e4771b94-3f76-48a0-aeac-8999c03b554a | HRT in post-menopausal women is given for all except:(AIIMS May 2013, Nov 2011) | Vaginal dry ness | Hot flushes | Prevention of coronary artery disease | Prevention of osteoporosis | 2c | multi | Ans. c. Prevention of coronary artery disease (Ref: Novak's Gynae 14/e p1330-1333)HRT in post-menopausal women is effective treatment available for relief of the menopausal symptoms hot flashes, vaginal dryness, urinary symptoms, emotional lability, and osteoporosis. Coronary artery disease is an absolute contraindicat... | Gynaecology & Obstetrics | Disorders in Menstruation |
c69f4c7e-ee9d-449b-a706-439a586d5558 | Radiological sign of coarctation of aorta | Dock's sign | E - sign | Inverted 3 sign | All of the above | 3d | multi | Others :
Revesed E sign.
Figure of 3 sign. | Radiology | null |
960fa5fb-6968-4e6d-a0a8-b8d8fe659e00 | 34 years old male with femur shaft fracturedevelops petechiae over chest 4 days after the injury. What is the most probable diagnosis? | Fat embolism | Air embolism | Thrombocytopenia | Hypocomplimentemia | 0a | single | Ans. is 'a' i.e., Fat embolism o Fat embolism means circulation of fat globule away from its site of origin,o When fat embolism causes symptoms it is called fat embolism syndrome,o Causes of fat embolism1. Fracture of long bone (most common) - Blunt trauma2. Soft tissue trauma3. Bums4. Parenteral lipid infusion5. Sickl... | Orthopaedics | Fracture Shaft Femur |
4a32fc1f-ad4a-4781-bad9-3e2162dae3ed | An obese, 25-year-old G1P0 comes to your office at 8 weeks gestational age for her first prenatal visit. She is delighted to be pregnant and wants to do whatever is necessary to ensure a healthy pregnancy. She is currently 5 ft, 2 in. tall and weighs 300 lb. She is concerned because she is overweight and wants you to h... | Marked obesity in pregnancy increases the risk of developing diabetes, hypertension, and fetal macrosomia | She should gain at least 25 lb during the pregnancy because nutritional deprivation can result in impaired fetal brain development and intrauterine fetal growth retardation | Obese women will still have adequate fetal growth in the absence of any weight gain during pregnancy | She should avoid initiating a vigorous exercise program to get in shape | 1b | multi | Women who are markedly obese are at increased risk of developing complications during pregnancy. Obese women are more likely to develop diabetes and hypertension during pregnancy. In addition, these women are more likely to develop fetal macrosomia and undergo cesarean section for delivery. Morbidly obese women who do ... | Gynaecology & Obstetrics | Fetus & New Born and their Diseases |
189ab8ce-de10-4356-b843-1073d6755fa6 | Which is not a perceptional disorder | Hallucination | Illusion | Synaesthesia | Imagery | 3d | multi | Imagery: awareness of a percept that has been generated within the mind, can be terminated by an effo of will. It is a pa of a normal phenomenon Hallucination: False sensory perception occurring in the absence of any relevant stimulation of the sensory modality involved. Types: auditory, Visual, tactile, gustatory, sme... | Psychiatry | All India exam |
825f74cd-4217-4bdf-9c66-81ca99f0e82a | A child of phenyl ketonuria mother may develop – | Microcephaly, mental retardation, congenital heart disease | Mental retardation, cataract, congenital heart disease | HydrocephaluS, cataract. | Microcephaly, cataract, renal dysplasia. | 0a | single | Children born to phenyl ketonuria mothers have following features
Mental retardation
Microcephaly
Growth retardation
Congenital heart disease | Pediatrics | null |
a696a24c-bdd3-46ab-a52c-ea5dc3b09422 | Sensorimotor neuropathy may be caused by all, except: | DM | Lead poisoning | Arsenic | Isoniazid | 1b | multi | Answer is B (Lead poisoning): Inorganic lead poisoning is not associated with a sensorimotor neuropathy Inorganic lead poisoning is primarily associated with a pure motor neuropathy. Selective motor neuropathy with wrist drop is characteristic of lead poisoning. Conditions that may cause Sensorimotor Neuropathies Polyn... | Medicine | null |
b4188801-88a1-4838-afa5-c1a1e3c1674e | Perinatal Moality rate includes: | Still borns and death within 7 days of bih | Neonatal deaths within 30 days of bih | Aboions and Death within 7 days of bih | Deaths between 7 and 28 days of bih | 0a | single | Perinatal moality rate has great significance in assessment of both obstetric and pediatric care before and around the time of bih. It includes both stillbihs and early neonatal deaths (neonatal deaths under one week of age). Perinatal moality accounts for 90% of all fetal and infant moality in the developed countries.... | Social & Preventive Medicine | null |
652a77e0-0b71-420a-8f09-e27ea1702a6e | Energy production enzymes are located in: | Rough endoplasmic reticulum | Ribosomes | Golgi apparatus | Mitochondria | 3d | single | Ans. (d) Mitochondria(Ref: Ganong, 25th ed/p.36)Mitochondria is involved in the synthesis of energy-rich compound ATP by oxidative phosphorylationAlso called as "powerhouse of the cell" | Physiology | General |
4a5c8ffe-3f91-4af1-8bf5-c7955fe4d1be | First symptom in tuberculous cord compression is- | Sensory change | Decrease tendon reflex | Spasticity | Lower limb weakness | 2c | single | Tubercular paraplegia is usually spastic to start with. | Orthopaedics | null |
7c49925d-cb65-46a4-93a4-aa5e7273cc6f | Rodent ulcer is | Basal cell cancer | Squamous cell ca | Rhinophyma | Adenocarcinoma | 0a | single | Basal cell cancer Aka Rodent ulcer Locally invasive Destruction of surrounding tissues - Aka Tear Cancer Seen in face above the line joining ear lobule to angle or corner of mouth - Arises from Basal layer of epidermis - Most common site - Nose > Inner canthus Types of BCC (based on pathology) - Nodular MC type Classic... | Surgery | FMGE 2019 |
5b52d6a7-c4d5-44fd-a817-4c6d8782aedb | Unilateral injury to hypoglossal nerve leads to all, EXCEPT? | Hemiatrophy of involved side | Detion of tongue towards the same side | Loss of taste sensation over the opposite half of the tongue | Fasciculation of the tongue | 2c | multi | Hypoglossal nerve is not involved in the transmission of taste sensation.General sensation from anterior 2/3rd of tongue is carried by lingual nerve, taste sensation is carried by chorda tympani a branch of facial nerve. Glossopharyngeal nerve carries both taste and general sensation from posterior 1/3rd of tongue. Pos... | Anatomy | null |
3d0125db-6375-4b2e-9da3-adf1d2a974d1 | A 30-year-old female complaints of fatigue and is unable to gain weight. On examination, her body felt warm. Which of the following investigation can be helpful in reaching the diagnosis? | High TSH with normal T3, T4 | Low TSH with high T3, T4 | High TSH with euthyroid status | Increased uptake of T3, decreased level of T4 | 1b | single | On the basis of above clinical scenario patient is suffering fromprimary Hypehyroidism. Primary Hypehyroidism CLINICAL FEATURES: Sympathomimetic stimulation : Palpitations - beta1 activation Fine Tremors - beta 2 activation Sweat on palms/soles Hypeension - alpha1 activation 2. BMR | -Weight loss 3. Calorigenesis | - H... | Medicine | NEET Jan 2020 |
7b95b699-c173-4e0a-8cad-9d4f102d3949 | All of the following are true about the Papovavirus, except | They are non-enveloped icosahedral viruses | Produce papilloma | RNA virus | Oncogenic | 2c | multi | Pox virus, Herpes virus, Adenovirus, HBV, Papilloma, Papova , Polyoma virus are DNA virus. Papillomaviruses cause infections at cutaneous and mucosal sites, sometimes leading to the development of different kinds of was, including skin was, plantar was, flat was, anogenital was, laryngeal papillomas, and several cancer... | Microbiology | Virology |
ae2c497a-a3df-4311-a392-ab95f9111afe | The most virulent plasmodium species causing malaria is: March 2013 (c) | Vivax | Ovale | Falciparum | Malariae | 2c | single | Ans. C i.e. Falciparum malaria Plasmodium falciparum It is a protozoan parasite, one of the species of Plasmodium that cause malaria in humans. It is transmitted by the female Anopheles mosquito. Malaria caused by this species (also called malignant or falciparum malaria) is the most dangerous form of malaria, with the... | Microbiology | null |
d795f77e-52f6-4b0e-9a9f-bdd755255735 | Gastric motility is increased in: | Acid in duodenum | Tryptophan in duodenum | Distension of stomach | Fatty food in stomach | 0a | single | Acid in duodenum | Physiology | null |
3127320e-04d9-462f-81c1-73789b27a6e9 | A 47-year-old man has had dull, constant pain in the midsection of the right thigh for the past 4 months. On physical examination, there is pain on palpation of the anterior right thigh, which worsens with movement. The right thigh appears to have a larger circumference than the left thigh. A radiograph of the right up... | Chondrosarcoma | Liposarcoma | Metastatic adenocarcinoma | Nodular fasciitis | 1b | single | A large, deep soft-tissue mass suggests cancer, most likely a sarcoma. Liposarcomas are located in deep soft tissues, can be indolent, and can reach a large size. They are the most common sarcomas of adulthood. Chondrosarcomas can be seen over a wide age range, but they arise within the bone. Carcinomas are far more co... | Pathology | Osteology |
a9573619-714a-41fd-bd4c-393298355791 | Drug of choice for acute congestive glaucoma is : | 1-2% pilocarpine | Timolol | Levobunanol | Atropine | 0a | single | A i.e. 1-2% Pilocarpine | Ophthalmology | null |
a283ed15-4339-4c4d-9967-0b3ab4006e6e | Esophagus enters abdomen through | Central tendon of diaphragm | Along aortic opening | Muscular part of diaphragm | Right crus | 2c | single | Oesophageal opening
- Level- T10
- At muscular portion derived from right crus
- Structures transmitted
Oesophagus
Oesophageal branch of left gastric artery
Vagus nerve | Anatomy | null |
4cca43d7-4de8-4c01-9e68-39aad581997e | Histamine release is one of the common features with administration of | Atracurium | Adrenaline | Thiopentone | Ketamine | 0a | single | histamine is released by atracurium , all skeletal musle relaxants release histamine other drugs releasing histamine are morphine,vancomycin etc. Ref: kd tRipathi 8th ed. | Pharmacology | All India exam |
5ef4139f-92cc-46b5-8b8d-4ddd7fbf450a | True about ASD : | Foramen ovale is patent | Left parasternal heeve is due to increased pulmonary aery flow | S2 is wide and variable | Systolic murmur is due to rapid flow of blood across the shunt. | 1b | multi | Answer is B (Left parasternal heeve is due to increased pulmonary aery flow) In ASD large volume of blood reaches the left atrium, right atrium, right ventricle and Pulmonary circulation. Consequently there is enlargement of LA, RV as well as of the pulmonary aery and its branches, and this may contribute to the left p... | Medicine | null |
40a735be-aa32-4120-aa04-942908fe366d | Which of the following biological fluids has the highest pH value? | Bile | Pancreatic juice | Saliva | Gastric juice | 1b | single | Pancreatic juice is alkaline and has the highest pH (7.8 - 8.0). Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions. | Physiology | null |
15f37dd5-de99-41ac-a77c-a0e107839a3b | Which field of vision is last to go in chronic simple glaucoma? | Nasal | Peripheral | Central | Temporal | 3d | single | Ans. d (Temporal). (Ref. Parson, Diseases of Eye, 18th/pg.216)# In POAG (chronic simple glaucoma) glaucomatous disc changes are characteristic with cupping starting in inferior temporal quadrant, followed by bayoneting sign, baring of circumlinear vessels, splinter haemorrhages, temporal neural rim, polar notching, lam... | Ophthalmology | Glaucoma |
f822dfed-f142-4583-b7c2-779cf63ccad6 | Fish tail deformity in a child is seen after injury to? | Distal Tibia | Distal Femur | Distal humerus | Distal Radius | 2c | single | Fishtail deformity of the elbowis characterized by a contour abnormality of the distal humerus, which develops when the lateral trochlear ossification centers fails to develop or resorbs. It is an uncommon complication usually following a distal humeral fracture in childhood.Whilst initially presumed to be a benign con... | Orthopaedics | AIIMS 2020 |
ee998901-aeb1-4859-a627-b2475c045118 | Commonest cause of hypothyroidism is | Defective synthesis of thyroxine | Defect of iodide transport | Defect of the thyroglobulin synthesis | Thyroid dysgenesis | 3d | single | (Thyroid dysgenesis) (1872-73-Nelson 17th) (481-Ghai 7th)HYPOTHYROIDISM results from deficient production of thyroid hormone or a defect in thyroid hormone or a defect in thyroid hormonal receptor activity* Someform of thyroid dysgenesis (aplasia, hypoplasia or an ectopic gland) is the most common cause of congenital h... | Pediatrics | Endocrinology |
883904fc-e3c3-47d1-b1c3-26113f0b1ee8 | Anuria is defined passing Less than _____ ml urine/day | 400ml | 3L | 100ml | 1000ml | 2c | single | Anuria <100ml.
Oliguria < 400ml. | Medicine | null |
03b310ff-2d80-422e-8b96-d774012a2807 | In which case Anterior resection is the method of tit ? | Ca sigmoid colon | Ca rectum | Ca colon | Ca anal canal | 1b | single | Ans 'b' ie Ca Rectum Anterior resection is the general term used to describe operations in which rectosigmoid pa is resected from an abdominal approach with no need for perineal, sacral or other incision. Resection of the rectosigmoid colon performed above the pelvic peritoneum is called high anterior resection. wherea... | Surgery | null |
ba9d8012-8259-4a60-a6ff-436e2fa96237 | Carpel tunnel syndrome is due to compression of - | Radial nerve | Ulnar nerve | Palmer branch of the Ulnar nerve | Median nerve | 3d | single | Carpal tunnel syndrome occurs when the median nerve is compressed in the carpal tunnel below flexor retinaculum. | Orthopaedics | null |
9e5fecdf-a0f4-45bb-851f-e731a236da06 | In pregnancy with increased MSAFP which of the following should be done : | Repeat measurement of MSAFP at later date | USG | Amniocentesis | Termination of pregnancy | 1b | single | Ans. is b i.e. USG "MSAFP values above 2.5 mom are considered abnormal. When a patient has an elevated MSAFP level, an ultrasound examination should be performed. This need not be a level scan. The reason for this examination is that it can detect several of the most common non genetic reasons causing high MSAFP values... | Gynaecology & Obstetrics | null |
812f0803-e05f-4a56-81c2-6b48ccc22df8 | The clinical manifestation of canda equina lesion include the following except- | Urinary retention | Radicular pain | Saddle anasthesia | Extensor plantar reflexes | 3d | multi | Cauda equina syndrome (CES) signifies an injury of multiple lumbosacral nerve roots within the spinal canal distal to the termination of the spinal cord at L1-2. Low back pain, weakness and areflexia in the legs, saddle anesthesia, or loss of bladder function may occur. The problem must be distinguished from disorders ... | Medicine | C.N.S |
a52cb630-0feb-4135-8742-2bf4768e2580 | In a case of hypertensive uveitis, most useful drug to reduce intraocular pressure is – | Pilocarpine | Latanoprost | Physostigmine | Dipivefrine | 3d | single | Glaucoma associated with uveitis is one of the most difficult complications to address and manage.
Medical therapy with topical or systemic antiglaucoma medications is the first step in the treatment of glaucoma-associated uveitis P-blockers, carbonic anhydrase inhibitors (acetamezolanzide), and dipivefrine.
β-blockers... | Ophthalmology | null |
1c737d8a-a416-4b4c-aa20-a885bfefec07 | Most Impoant component of level of living is | Health | Education | Occupation | Housing | 0a | single | Impairment of health always means impairment of the level of living. hence health is the most impoant. Level of living is a parallel term for standard of living used in United Nations. It includes 9 components. Ref : Park&;s Textbook of Preventive and Social Medicine; 23rd edition - Pgno 16 | Social & Preventive Medicine | Concept of health and disease |
1b39db12-8ac8-41d9-9a2f-25cc08ffa23b | Heterotopic ossification is a condition in which there is deposition of bone around the joints. Which of the following parameters is the most useful for this condition - | Serum calcium | Serum phosphate | Serum alkaline phosphatase | Serum PTH | 2c | single | Bone scan ( Tc 99 three phase scan) is the most sensitive for early detection of heterotropic ossification. ALKALINE PHOSPHATASE and 24hr PGE2 are screening tests for heterotropic ossification. REF:Essential ohopaedics- Maheshwari- 5th edn - pg no 53. | Orthopaedics | Miscellaneous |
6e4a6483-9d7e-461c-962c-f4d3bc734856 | Most common presentation of adult rhinosporidiosis is - | Halitosis | Pain | Anosmia | Polypoidal mass | 3d | single | Ans. is 'd' i.e., Polypoidal mass Rhinosporidiosiso Rhinosporidiosis is a chronic granulomatous infection of the mucous membrane that usually manifests as vascular friable polyps that arise from the nasal mucosa. The etiological agent is Rhinosporidium seeberi. Rhinosporidium seeberi is an aquatic protozoan (not a fung... | Unknown | null |
3ad5b6f1-0144-4eb6-9a87-b6367e8b957b | Drug of choice for Bupivacaine induced cardiac arrythmia | Amiodarone | Procainamide | Bretylium | Flecainide | 2c | single | Bretylium is a class III Antiarrythmic used to treat Bupivacaine induced ventricular tachycardia. | Pharmacology | null |
e9103675-9d86-40bd-b089-991b3f3c1e78 | Dinner fork deformity is seen in? | Colle's fracture | March fracture | Lateral condyle fracture | Supracondylar fracture | 0a | single | Ans. is 'a' i.e., Colle's fracture Complications of colle's fracture Complications in colle's fracture are high (50-60%). Following complications may occur 1) Stiffness of fingers and joints Stiffness of finger, wrist and shoulder is the most common avoidable complication of colle's fracture. This occurs due to lack of... | Surgery | null |
392e6ccf-3b93-4409-9218-030b727eb95c | UMN includes | Pyramidal cells | Peripheral nerves | Anterior horn cells | Glial cells | 0a | single | Upper motor neuron- Pyramidal cells, corticospinal tract, corticobulbar tract, extrapyramidal tracts. | Physiology | null |
28bc2ada-72f4-4c94-9575-2b972c09b5f2 | True about pelvic abscess | Uncommon cause of intraperitoneal abscess | Identified by CT if there is a full bladder | Associated with pyothorax | May spontaneously drain via rectum | 3d | multi | Ans. (d) May spontaneously drain via rectumRef: Sabiston I9th edition Page 1312* Pelvic abscess is the mc site of abscess formation in sitting position.* Rutherford Morrison pouch is the mc site of abscess formation in lying position.* Pelvic abscess is drained via rectum.* Pelvic abscess is associated with diverticuli... | Surgery | Peritoneum |
3849bd4f-bb31-4a49-9fce-7e5aaec758fa | Diagnosis of a man with diffuse hair loss involving crown & frontal scalp with maintenance of frontal hairline – | Alopecia areata | Anagen effluvium | Male pattern baldness | Female pattern baldness | 3d | single | Information in this question are :-
Diffuse hair loss involving crown and frontal scalp.
Maintenance of frontal hair live.
These two suggest the diagnosis of female pattern hair loss :-
Information (i) above suggests the diagnosis of androgenic alopecia which may be either male pattern or female pattern → Essenti... | Dental | null |
ced99966-5f49-4182-beff-3b34ee188939 | Primary level of prevention is? | Prevention of emergence of risk factors | Prevention of disease in Pre-pathogenesis phase | Prevention of disease in incipient stage | Prevention of disability and rehabilitation | 1b | single | Modes Primordial Before the emergence of risk factor Health education Primary Risk factor but no disease yet Health promotion, specific protection Secondary Disease possible staed in the body Early diagnosis, Treatment Teiary Disease is already in progression Disability limitation , Rehabilitation | Social & Preventive Medicine | Levels of Prevention of Disease |
19b6e22b-9edc-4b84-b665-0d97ff001c55 | All of the following is/are true regarding candidiasis: | Commonly involve mucosa & skin | Not involve nails | Caused by yeast like fungus | Diabetes is most impoant risk factor | 1b | multi | Ans: (B) Not involve nails.It is an infection of skin, mucosa & rarely of internal organsIt is caused by yeast like fungus, Candida albicans & occasionally by other candida speciesUbiquitous in nature, these organisms are found on inanimate objects, in foods, and on animals and are normal commensals of humans. They inh... | Microbiology | null |
3de6c2e1-a9d9-43a2-9e67-00d621063fc7 | All of the following statements about mosquito are true except - | It is definitive host in malaria | It is a definitive host in filaria | Its life cycle is completed in 3 weeks | The female can travel upto 3 kilometers | 1b | multi | Man is the definitive host and mosquito is the intermediate host of Bancroftian and Brugian filariasis. Park's Textbook of Preventive and Social Medicine, 25th edition, Page No. 832 | Social & Preventive Medicine | Environment and health |
b59da329-20a5-4d6d-a676-1cd6957c9dfb | Which of the following antibacterial drug is polar? | Ampicillin | Penicillin G | Clavulanic acid | Cefepime | 0a | single | Ans. is 'a' i.e., Ampicillin Ampicillin: It is an ionized highly polar drug. In the duodenum it exes a zwitter ion effect and thus has a lower bioavailabilty. Though the oral absorption is incomplete it is adequate. It is an antibacterial drug acting both on gram positive and gram negative organisms. Main mode of excre... | Pharmacology | null |
a579d0f2-cb44-487f-9c4a-8541345173da | In myocardial infarction, the infarct acquires hyperemic rim with a yellow center at | 1-2 hours | 3-7 days | 7-14 days | 10-20 days | 1b | single | Findings of infarct at 3 - 7 days: Gross examinationHyperemia borderSoftening yellow-tan center Histopathology (light microscopy)The beginning of the disintegration of dead muscle fibersNecrosis of neutrophilsThe beginning of macrophage removal of dead cells at the border | Microbiology | All India exam |
d7b8c89c-2a57-4126-8e09-503ad154c2cb | All of the following are true about Darier's disease except: | Defect in calcium ATPase because of mutation in ATP2A2 gene | Corps ronds and corps grains are seen | Subepidermal blister | V-shaped nicking of nail is present | 2c | multi | Both Hailey Hailey disease and Darier's disease are characterized by suprabasal acantholysis / suprabasal blister. | Dental | null |
8604e8f7-fcae-46d6-8170-e87fb1ed3d2b | Cervical veebrae can be differentiated from thoracic veebrae on the basis of which of the following features? | Triangular body | Presence of foramen transversarium | Superior aicular facet which is directed backwards and sidewards | Presence of a large veebral body | 1b | single | Foramen transversarium is a characteristic feature of cervical veebrae. Foramen transversarium of transverse process of cervical veebrae transmits:Veebral aery,Veebral veins,Branch from the inferior cervical sympathetic ganglion.Thoracic veebrae is chracterised by the presence of costal facets in the body.Lumbar veebra... | Anatomy | null |
5422becb-68b8-4687-bf6a-ccba263b206b | Stoke Adam's associated with | Sinoatrial arrest | Tachyrhythmias | High degree AV Block | Polymorphic ventricular tachycardia | 2c | single | (C) High degree AV Block # Those with syncope due to high degree AV block (Stokes-Adams-Morgagni syndrome) may have evidence of conduction system disease (e.g., prolonged PR interval, bundle branch block).> Bradyarrhythmias may occur as a result of an abnormality of impulse generation (e.g., sinoatrial arrest) or impul... | Medicine | Miscellaneous |
1964ea00-b5e0-4185-8489-5ddb249a804c | Increased level of 5 HLAA is present in: | Alkaptonuria | Albinism | Carcinoid tumor | Phenylketonuria | 2c | single | Ans. c. Carcinoid tumorRef: Bailey and Loves Short Practice of Surgery 27th Ed; Page No-1251CARCINOIPSYN DROMEDue to the metastasis of carcinoid tumors, which most commonly arise from the ileum and appendix and produce serotonin. Prior to metastasis, most secreted hormones undergo first-pass metabolism by the liver and... | Surgery | Pancreas |
b7d6c50b-262f-4a30-a633-d06e5ad1f82d | A patient with nephritic syndrome will not have September 2009 | Hematuria | Mild to moderate proteinuria | Hypeension | Normal RBC | 3d | single | Ans. D: Normal RBC | Pathology | null |
361ac9e6-7fe0-4b6e-9351-3f62528b5103 | Rinne's test is negative if minimum deafness is - | 15-20 dB | 25-30 dB | 35-40 dB | 15-50 dB | 0a | single | As discussed in the text in Rinnies test—air conduction of the ear is compared with its bone conduction.
Hence there is false negative Rinne test (BC > AC). | ENT | null |
9dbd4d81-99ae-4131-8921-14c2942c26ab | The initial pharmacologic therapy of choice in this stable patient (refer to Q 87) is | Adenosine 6 mg rapid IV bolus | Verapamil 2.5 to 5 mg IV over 1 to 2 min | Diltiazem 0.25 mg /kg IV over 2 min | Digoxin 0.5 mg IV slowly | 0a | single | Vagotonic maneuvers such as carotid massage or the Valsalva maneuver could ceainly be tried first. If these are unsuccessful, adenosine, with its excellent safety profile and extremely sho half-life, is the drug of choice for supraventricular tachycardia at an initial dose of 6 mg. Dosage can be repeated if necessary a... | Surgery | null |
5c985d2c-e69f-455a-b449-1b841b442372 | Major aim of phase 1 clinical trials is to know the | Safety | Efficacy | Maximum Tolerable Dose | Pharmacokinetics | 2c | single | Phase I trial is designed as a dose-escalation study to determine the maximum tolerable dosage (MTD), that is, the maximum dose associated with an acceptable level of dose-limiting toxicity. Phase 1 Clinical Trials: The drug is tested in healthy human volunteers (extremes of ages ; elderly and children are excluded). A... | Pharmacology | CLINICAL TRIALS, DRUG LABEL |
5544a8ec-67c9-4e42-b710-4db90dccc329 | True statement regarding inverse agonists is? | Binds to receptor and causes intended action | Binds to receptor and causes opposite action | Binds to receptor and causes no action | Binds to receptor and causes submaximal action | 1b | multi | Ans. is 'b' i.e., Binds to receptor and causes opposite action | Pharmacology | null |
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