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pair_32842291
The National Standards for Students' Physical Health (2014 revision)is a standard for providing primary guidance for the national school education work and applicable to the evaluation of the physical health of primary school, secondary school and university students in China. This standard sets indicators and assessme...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
《国家学生体质健康标准(2014年修订)》是国家学校教育工作的基础性指导文件,适用于评价中国大、中、小学生的体质健康水平。该标准从身体形态、机能和素质3方面,分性别、年级设定指标和评定分值,综合评定学生体质健康水平。由于应用过程复杂、指标众多,在样本量大的情况下应用效率较低且容易误用。为此,本研究结合案例详细介绍了该标准的应用方法,并编制了相应的SPSS程序包供相关人员下载使用,有利于快捷且准确地评价学生体质健康水平。.
zh-cn
pair_32842294
Harmful drinking causes serious consequences to social security as well as physical and mental health of the general public. The Global Burden of Disease Study (2017) showed that the number of alcohol-related deaths in China in 2017 was 1.82 times higher than that in 1990, and the population attributable fraction incre...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
有害饮酒给社会安全和身心健康带来严重危害。全球疾病负担研究(2017)显示2017年我国饮酒致死的人数是1990年的1.82倍,导致的死亡人群归因分值增幅达44.13%。饮酒导致的疾病负担日益严重。通过与世界卫生组织提出的限制有害饮酒综合干预策略比对分析发现,我们认为当前我国有待完善的干预领域包括加强酒类生产、销售和流通环节的管控,通过企业自律、法规宣贯、家长和学校健康教育限制未成年人的酒类产品的可获得性;在医疗卫生体系中填补限酒/戒酒适宜技术和服务的空白,提供酒精依赖快速筛查、简短戒酒干预等服务;加强酒类广告的限制措施,尽快出台新媒体(如网络、社交媒体)酒类产品营销活动规范;针对酒税问题开展科学研究和评估,定期审查与通货膨胀和收入...
zh-cn
pair_32842303
In 2018, the myopia detection rate of children and adolescents aged 5-18 years old in Shaanxi Province was 54.9% (11 060/20 144). The myopia detection rate of girls [58.6%(5 830/9 949)] was higher than that of boys [58.6% (3 416/5 830)] (<i>P</i><0.001). In children and adolescents, the myopia detection rate increased ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2018年陕西省5~18岁儿童青少年近视检出率为54.9%(11 060/20 144),女生近视检出率[58.6%(5 830/9 949)]大于男生[58.6%(3 416/5 830)](<i>P</i><0.001)。儿童青少年近视检出率在16‌岁之前随年龄增加而增加,16‌岁之后呈平稳甚至下降的趋势。调整相关混杂因素后,与人均GDP<5万元地区相比,人均GDP>10万元地区的儿童青少年近视检出率均较高[<i>OR</i>(95%<i>CI</i>)值为1.58(1.34~1.87)]。.
zh-cn
pair_32842304
Rotaviruses infection is one of the main causes of diarrhea among infants and children in the world, resulting in rotavirus gastroenteritis, which is very harmful and has caused a huge disease burden and no specific drug treatment. This paper reviews the rotavirus etiology, epidemiological characteristics, disease burd...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
轮状病毒(RV)感染是目前全球婴幼儿腹泻的主要病原之一,直接导致轮状病毒胃肠炎,其危害严重、疾病负担巨大且尚无特效药物治疗。本文对RV病原学特性以及RV胃肠炎的流行特征、疾病负担和疫苗研发予以综述。通常A组RV为婴幼儿急性胃肠炎的最主要病因,各年龄段人群对RV普遍易感,其中3~24‌月龄的幼儿症状最重,且RVGE流行具有季节性,并在冬季会出现发病高峰,提高RV疫苗接种率可以显著降低婴幼儿轮状病毒腹泻发病率和死亡率,减轻相应疾病负担。重点介绍了目前使用的RV疫苗及其对预防RV感染的作用,并针对RV疫苗在我国应用相关技术问题提出思考与建议,为完善我国RV疫苗免疫策略及最终将RV疫苗纳入到国家儿童免疫规划的中国特色免疫规划策略提供循证依据...
zh-cn
pair_32842305
In 1999, since the Rotashield, the first generation of oral Rotavirus vaccine has been confirmed that there is a link to intussusception, mainly occurs in 7 days after first dose. With the second generation of RV vaccine has been listed globally and intussusception monitoring has continued. This study reviewed the curr...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
1999年第一代口服轮状病毒疫苗(ORV)Rotashield被发现与肠套叠发病风险增加有关,集中在首剂接种后7 d内,随之疫苗下市。后第二代ORV在全球陆续上市,并开展肠套叠风险监测及研究。本研究回顾了目前上市使用轮状病毒疫苗Ⅲ期临床及上市后研究相关证据,使用最广泛的2‌种轮状疫苗RV1和RV5在多国实践中发现ORV接种后的7 d内肠套叠风险增加。我国目前使用的国产口服轮状病毒减毒活疫苗(LLR)则缺乏相关研究。2018‌年RV5在我国正式上市,轮状病毒疫苗在防控轮状病毒重症腹泻的作用加大,故急需建立肠套叠主动监测系统以监控轮状病毒疫苗使用后肠套叠的发病情况,为轮状病毒疫苗上市后评估提供更多证据。.
zh-cn
pair_32842306
With the increasing number of environmental chemicals, the risk assessment system based on animal toxicity testing is difficult to satisfy the current demands and needs to be reformed urgently. With the wide application of high-throughput screening technology, the advantage of exposomics in risk assessment is gradually...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
进入环境化学物的数量日益增长导致基于动物毒性测试的风险评估体系难以满足当前需求,亟待变革。伴随高通量检测技术的广泛应用,暴露组学在风险评估中的应用价值逐渐显现,通过对环境外暴露和机体内暴露水平的动态监测,研究生命不同时期(尤其是生命早期)环境混合暴露对健康的影响。在风险评估中引入暴露组学,系统研究基因-环境交互作用,为构建暴露-生物标志物-疾病发生网络提供可靠依据。本综述从暴露组学研究进展、在风险评估中的应用和当前存在的问题、机遇与挑战,概述暴露组学在环境化学物风险评估中的重要性和应用前景。.
zh-cn
pair_32842307
Repeated measurement data is a common type of data in medicine, whichcan not be simply compared at each time point, and a professional statistical analysis method should be used to analysis this kind of data. Three common statistical methods were introduced for repeated measurement data, including repeated measurement ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
重复测量数据是医学中常见的一种数据,该数据的分析不能简单对每个时间点分别比较,而应采用专业的统计分析方法。本文介绍了目前重复测量数据常见的三种方法,即重复测量方差分析、广义估计方程和多水平模型,并基于实例对三种方法的具体软件实现、结果解读进行了详细解释,同时对三种方法实际应用的情形进行了分析比较,以期临床科研人员能够正确分析重复测量数据,提高数据的分析效率。.
zh-cn
pair_32842308
COVID-19 is a public health emergency currently. In this study, a scale-free network model is established based on the Spring Migration data in 2020.The cities is clustered into three different modules. The epidemic of the cities in the black module was the most serious, followed by the red and the cyan. The black modu...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
新型冠状病毒肺炎是当下重要的公共卫生问题。本文利用2020年农历春节前15天各城市流动人口数据建立无尺度网络模型,动态剪切树算法实现城市聚类,得到黑色、红色和青色三大城市模块。黑色模块内城市疫情最为严重,红色其次,青色最轻。黑色模块包含浙江省9座城市,广东省8座城市,且绝大部分位于东南沿海经济带,应作为疫情防控的重点城市。.
zh-cn
pair_32842318
To explore the relationship between parental hypertension history and hypertension in children and adolescents based on the relevant data of 6 049 children and adolescents aged 6 to 17 years old in Jinan city from September 2012 to September 2014. The results showed that the history of hypertension in parents was posit...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
基于2012年9月至2014年9月济南城区6 049名6~17岁儿童青少年的相关资料,探讨父母高血压史与儿童青少年高血压的关联。结果显示,父母高血压史与儿童青少年收缩压呈正相关,β(95%<i>CI</i>)值为0.91(0.23~1.59);父母一方有高血压史、父母双方均有高血压史的儿童青少年罹患高血压的可能性均较大,<i>OR</i>(95%<i>CI</i>)值分别为1.28(1.01~1.61)、2.24(1.09~4.61)。因此,建议针对父母有高血压史的儿童青少年,应尽早采取预防和干预措施。.
zh-cn
pair_32842319
From June 2017 to June 2018, female sanitation workers engaged in road cleaning in a district of Urumqi City, as well as government and logistics women participating in national health examination in the same community were recruited as particulate matter 2.5 (PM<sub>2.5</sub>) exposure group and control group respecti...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
于2017年6月至2018年6月,招募乌鲁木齐市某区从事道路清洁的环卫女工和同小区内参加全民健康体检的机关、后勤女性分别作为PM<sub>2.5</sub>暴露组和对照组,研究PM<sub>2.5</sub>长期暴露对环卫女工性激素水平的影响。PM<sub>2.5</sub>暴露组的促卵泡生成素(FSH)、促黄体生成素(LH)含量[分别为(7.85±9.87)、(8.74±10.51)mIU/ml]均低于对照组[分别为(14.40±19.14)、(13.17±14.57)mIU/ml](<i>P</i>值均<0.05)。进一步分析发现,35~39、40~44、45~49岁暴露组的FSH含量低于对照组,35~39岁和45~49岁暴露组...
zh-cn
pair_32842320
A total of 189 new cases of gastric cancer in Sheyang County from 2014 to 2018 were selected as the case group, and 189 other people without gastric cancer were matched according to age and gender as the control group. A case-control study was conducted on the relationship between drinking water and gastric cancer. Aft...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
选择2014—2018年射阳县189例胃癌新发病例作为病例组,按照年龄、性别匹配189名其他未患胃癌人群作为对照组,开展居民饮水情况与胃癌关联的病例对照研究。多因素logistic回归模型结果显示,调整体重指数、家庭年收入、饮食口味、每月腌菜食用量、每月辣椒食用量、每月豆制品食用量、经历不幸、患浅表性胃炎、胃癌家族史因素后,与10年前饮水末梢无污染源、饮用开水为主者相比,10年前饮水末梢有污染源、只喝生水者胃癌的患病风险较高[<i>OR</i>(95%<i>CI</i>)值分别为2.20(1.13~4.29)、6.12(1.25~29.93)];与饮水来源为自来水相比,饮用净水处理后水者胃癌患病风险较低[<i>OR</i>(95%<...
zh-cn
pair_32842321
In recent years, both benign and malignant thyroid tumors have grown rapidly in the world, and have become one of the most common tumors in the endocrine system. At present, the pathogenesis of thyroid tumor is still unclear, but more and more studies have found that certain factors are related to the occurrence and de...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
近年来在全球范围内,甲状腺良、恶性肿瘤均增长迅速,成为内分泌系统最常见肿瘤之一。目前甲状腺肿瘤发病机制仍不明确,但越来越多研究发现某些因素与甲状腺肿瘤的发生发展有关,对这些危险因素进行总结分析具有重要意义。本文将综述近年来其危险因素的研究进展,为甲状腺肿瘤的精准和科学防控提供依据。.
zh-cn
pair_32842322
With the wide application of nanomaterials in consumer products in the market, it is necessary to understand the existence and release of nanomaterials in consumer products, as well as the current situation of exposure assessment of consumers. China has been a large industrial producer with a huge consumer market, but ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着纳米材料在市场上消费品中广泛应用,了解纳米材料消费品中纳米材料的存在及释放,以及消费人群的暴露评估现状非常必要。中国是工业生产大国,拥有巨大的消费市场,但是对纳米材料消费品的监管几乎空白。本文对国际市场上现有的纳米材料消费品进行了汇总分类,探讨了重点纳米材料在消费品中的释放和消费人群的暴露评估方法,旨在为我国未来建立对纳米材料消费品的监管体系提供科学依据。.
zh-cn
pair_32842323
Joinpoint regression is a common method to investigate epidemiological time trend. Here we took cancer incidence trend analysis as an example to demonstrate the theory and practise of model from principles, steps, examples and attentions to give some references for following similar studies.
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Joinpoint回归模型分析是流行病学时间趋势分析的常用方法。本文以肿瘤发病时间趋势分析为例,从模型的基本原理、分析步骤、实例演示和注意事项等方面进行系统阐述,以期将模型的方法原理与操作实践有机结合,为读者开展类似的研究分析提供参考。.
zh-cn
pair_32842324
Since the founding of the People's Republic of China, the diagnosis and treatment technology of corneal diseases has developed rapidly. In the field of infectious keratopathy, China was the first country that discovered chlamydia trachomatis in the world, which promoted the study on the pathogenesis as well as the diag...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
新中国成立以来,角膜病的诊疗技术得到快速发展。在感染性角膜病诊疗、手术技术发展、眼库建设、角膜相关检查设备等方面,均取得了巨大进步,使得我国角膜病从新中国成立初期的首位致盲性眼病下降为第2位。在回顾我国角膜病诊疗技术70年的发展和瞩目成绩的同时,尚应认识到存在的不足。站在老一辈眼科工作者的肩上,我们应继续努力,为角膜盲患者的复明贡献更大的力量。谨以此文祝贺《中华眼科杂志》创刊70周年。<i>(中华眼科杂志,2020,56:401-408)</i>.
zh-cn
pair_32842325
Dry eye is a common ocular surface disease that can occur in more than half of cataract patients before surgery. The perioperative damage to ocular surface can lead to tear film insufficiency and a series of dry eye symptoms, which reduce the visual outcome and life quality of the patients. Therefore, clinicians should...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
干眼是一类常见的眼表疾病,超半数白内障患者白内障摘除手术前即患有干眼。围手术期多种原因引起的眼表损伤易导致患者术后泪膜稳定性下降,出现一系列干眼相关不适症状,降低患者视觉效果及生活质量。因此,临床医师应从术前眼表情况的评估及改善、术中眼表的保护以及术后干眼的诊断和治疗等多方面入手,在围手术期加强干眼及相关眼表疾病的规范化管理,进一步提升白内障患者的手术满意度。<i>(中华眼科杂志,2020,56:409-413)</i>.
zh-cn
pair_32842326
This article was published ahead of print on the official website of Chinese Journal of Ophthalmology on February 24, 2020. In China, the fight against the 2019 novel coronavirus (2019-nCoV) has been at a critical stage. It has been confirmed that the transmission of 2019-nCoV is mainly through respiratory droplets and...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
本文于2020年2月24日优先发布于中华眼科杂志官网。目前我国防治2019新型冠状病毒(2019-nCoV)疫情的工作到了关键时期。虽然已明确2019-nCoV主要通过呼吸道飞沫和接触传播,但也有学者指出消化道和眼部亦可能是病毒另外的传播途径。感染2019-nCoV是否会出现眼部症状以及疾病是否会通过眼部传染,是医学界和大众关注的问题,深入探讨该问题成为眼科工作者的重要责任。本文从病毒性疾病的眼部表现入手,分析眼部分泌物和泪液是否携带病毒、眼科医务人员和患者是否为病毒传播的另一高危人群,指出目前眼科研究的途径以及必要的防控措施,希望在抗击2019-nCoV的战役中贡献眼科医务工作者的一份力量。<i>(中华眼科杂志,2020,56:4...
zh-cn
pair_32842330
Vision is the receptive and cognitive process of converting light and pattern signals into nerve impulse signals. The main role of visual physiology is to elucidate the neural mechanism of vision. As an important part of visual physiology, visual electrophysiological examination, like electrocardiogram and electroencep...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
视觉是对周围世界各种光和图形信号转变为神经冲动信号的接受过程和认知过程。视觉生理学的主要任务是阐明视觉产生的神经机制,作为视觉生理学重要内容的视觉电生理检查以及心电、脑电检查均是通过机体器官组织活动时产生的生物电现象诊断疾病。从新中国成立至今,我国视觉生理学科经过数代人 70 余年的传承和艰苦努力,在相关基础研究、转化研究以及临床研究等方面均取得了显著成绩,但是还有很多未知领域需要进一步探索。回顾发展历程,让我们砥砺前行,在视觉生理学科领域留下更多中国学者里程碑式的贡献。谨以此文祝贺《中华眼科杂志》创刊 70 周年。<i>(中华眼科杂志,2020,56:481</i>-<i>488)</i>.
zh-cn
pair_32842331
Clinical visual electrophysiological examination is a method that can objectively reflect visual function. It has become one of the important methods of ophthalmological examination, and the operation process has strict specifications. This article introduces the history, formulation and content of international clinic...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
临床视觉电生理检查是可客观反映视功能的方法,已成为眼科检查的重要手段之一,其检查流程有严格的规范。本文通过介绍国际临床视觉电生理检查标准的来源、制定目的及核心内容,帮助广大眼科临床工作者理解加强检查流程规范化的重要意义,从而更加规范推广我国的眼科临床视觉电生理检查工作。<i>(中华眼科杂志,2020,56:489-491)</i>.
zh-cn
pair_32842337
A 19-year-old woman presented sudden visual loss in the left eye for 1 day. Ophthalmic examination showed superior hemi-retinal whitening with thickening of the inner retinal layer and shadowing of the outer retina layer and delayed perfusion of the superior hemi-retinal artery and cilioretinal artery. We performed sur...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
对1例左眼上方半侧视网膜中央动脉阻塞患者(女,19岁)在发病34 h内行玻璃体切除联合视网膜静脉插管术(附手术视频),术中向视盘周围颞上分支静脉推注平衡盐溶液,至液体经视网膜静脉逆流进入邻近视网膜中央动脉。术后尽管形态学仍有损伤,但术眼视力从术前0.05提高至术后1.0。采用该方法治疗视网膜中央动脉阻塞,值得尝试和进一步研究。<i>(中华眼科杂志,2020,56:536-538)</i>.
zh-cn
pair_32842338
Neuromyelitis optica spectrum disorders (NMOSD) related optic neuritis (NMOSD-ON) is a common neuro-ophthalmic disease which often results in permanent blindness. NMOSD is characterized by high recurrence rate and poor prognosis. Therefore the two key objectives of the therapeutic approach for patients with NMOSD are t...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
视神经脊髓炎谱系疾病相关性视神经炎是引起患者视力严重下降的常见神经眼科疾病。视神经脊髓炎谱系疾病具有复发率高、预后差的特点。控制急性炎性反应、预防复发是视神经脊髓炎谱系疾病治疗的两个主要目标。随着对视神经脊髓炎谱系疾病发病机制的深入研究,不断出现针对病变发生过程中不同阶段新的治疗方法。本文就视神经脊髓炎谱系疾病相关性视神经炎的治疗现状和治疗前景综述如下。<i>(中华眼科杂志,2020,56: 539-543)</i>.
zh-cn
pair_32842339
Crouzon syndrome is an autosomal dominant disorder characterized by acrocephaly, exophthalmos, hypertelorism, strabismus, parrot-beaked nose, and hypoplastic maxilla. It is usually caused by a pathogenic mutation in the fibroblast growth factor receptor 2 gene and premature fusion of the sutures of the cranium and the ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Crouzon综合征是一种常染色体显性遗传性疾病,主要表现为头颅畸形(舟状头或三角头畸形),面部畸形(鹦鹉嘴样鼻、下颌前突),双眼突眼及斜视。Crouzon 综合征主要由成纤维细胞生长因子受体2基因突变所致。颅底甚至部分颅骨穹窿的骨缝过早的闭合为Crouzon综合征发病的始动因素。本文从Crouzon综合征患者发病机制、眼科相关病变的发生、行颅面外科手术后可能的眼科并发症表现及发生机制、治疗方面的进展进行综述,旨在增加眼科医师对该病的了解。早期颅眶外科手术有利于防止视神经萎缩和暴露性角膜炎引起的视力损害。对就诊于眼科的患者早期应行验光和眼球运动检查,防止屈光不正和斜视导致的弱视发生,及时进行斜视矫正手术治疗。<i>(中华眼科杂志,2...
zh-cn
pair_32842341
Clear aligners are the fastest-growing appliances in this century, which are not only favored by patients, but also concerned by doctors. This article explains the significance of vertical control in orthodontic treatment, the advantages and disadvantages of vertical control with clear aligner. It also analyzes the cau...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
无托槽隐形矫治是本世纪发展最迅猛的矫治技术,不仅受到患者青睐,也颇受医师关注。本文阐述正畸治疗中垂直向控制的意义,无托槽隐形矫治在垂直向控制上的优势与不足,分析发生不足的原因以及如何利用现有技术和方法弥补这些不足,以期为正畸临床提供参考。.
zh-cn
pair_32842342
Clear aligner, covering the whole dentition, is considered to offer more stable anchorage units, which means the whole dentition would act as a strong anchorage except the teeth designed to move. Although we don't expect any movement of the anchorage teeth, it actually happens. It reminds us to pay attention to anchora...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
透明矫治器包裹整个牙列,被认为能提供更好的组牙支抗,即除拟移动的牙齿,牙列内剩余牙齿整体作为支抗。然而实际移动牙齿时不期望发生移动的支抗牙也可产生移动,提示无托槽隐形矫治同样需要关注支抗问题。本文就无托槽隐形矫治中支抗控制问题进行阐述,对比固定矫治与无托槽隐形矫治支抗的区别,并从垂直向、矢状向和横向3个方面探讨支抗设计的临床策略,以期为正畸临床提供参考。.
zh-cn
pair_32842343
Clear aligner (CA) treatment achieves therapeutic goals through digital dental models and tooth movement planning. In recent years, with the increasingly wider clinical application of CA, orthodontists are frequently faced with the important choice of tooth extraction or non-extraction in treatment planning. This artic...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
近年,无托槽隐形矫治在正畸临床应用得日益广泛,而正畸医师在进行方案设计时常需面对减数与非减数这一大方向的重要抉择。本文从无托槽隐形矫治提供间隙的方法,选择减数与非减数方案的重要性和依据,以及具体临床策略几方面进行论述,强调应通过切牙、磨牙的定位以及数字化矫治模拟进行减数与非减数方案的精准判断。.
zh-cn
pair_32842344
The application of clear aligner technique in the preventive and interceptive treatment of children with malocclusion is a new hot spot in orthodontics, which has an extensive application prospect. However, the main advantage of this technique is the ability of predictable tooth movements. Early treatment of malocclusi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
在儿童错牙合畸形的早期矫治中应用无托槽隐形矫治技术是目前正畸临床的新兴热点,有较广泛的应用前景。无托槽隐形矫治技术的主要优势在于精确移动牙齿,而错牙合畸形早期矫治常涉及肌功能调整、颌骨矫形治疗、乳恒牙替换等诸多问题。因此,选择无托槽隐形技术开展早期矫治,必须严格控制适应证,避免盲目应用,并且在方案设计及临床监控方面仔细斟酌,扬长避短,才能为广大儿童患者提供安全舒适的治疗。.
zh-cn
pair_32842345
Clear aligner is a kind of removable orthodontic appliance, which designed and manufactured using digital technology. It is more and more widely used in adults and patients with periodontal disease. Clear aligner treatment in patients with moderate and mild periodontal diseases can achieve good result. Meanwhile, there...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目前,无托槽隐形矫治被越来越多地应用于成人正畸治疗及牙周病患者的正畸治疗中。对于轻中度牙周病患者,无托槽隐形矫治可获得较好的矫治效果;对于重度牙周病患者,无托槽隐形矫治仍存在风险,需严格把控适应证。明确牙周病患者的正畸治疗目标,严格控制牙齿移动范围,多学科联合治疗疑难病例,是正畸临床需关注的内容。牙周病患者无托槽隐形矫治时需确定可行的矫治目标位,根据牙周情况进行合理分步、设置适当的附件以及设计减小牙龈刺激的矫治器边缘。本文针对无托槽隐形矫治在牙周病患者正畸治疗中的应用领域,从适应证选择、矫治目标、矫治器设计、多学科联合治疗中的作用以及矫治器对牙周健康的影响等方面进行探讨。.
zh-cn
pair_32842346
Deciduous caries and abnormal tooth development are common children's oral diseases which seriously harm the health of deciduous dentition, hinder the absorption of nutrients and affect the general growth and development. Caries of deciduous teeth progresses rapidly and can develop into rampant caries and other hard ti...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
乳牙龋病和牙齿发育异常等疾病严重危害乳牙列健康,妨碍营养吸收,影响生长发育。乳牙龋损进展快,可在短时间内发展为猖獗性龋等牙体硬组织疾病。金属预成冠是一种适用于儿童严重牙体组织损害修复治疗、由不锈钢预制的牙冠。金属预成冠的修复技术有一定的操作程序,需要专门的器械和材料,由合格的口腔执业医师完成。中华口腔医学会儿童口腔医学专业委员会组织专家,制定乳牙金属预成冠修复临床操作规范,规范乳牙金属预成冠在儿童龋病等乳磨牙修复治疗中的应用,以利其进一步推广应用。.
zh-cn
pair_32842351
Tooth loss is a common disease in the elderly, and periodontitis is the main cause of tooth loss. Alzheimer's disease is a primary degenerative brain disease which etiology remains unknown. The patients often demonstrate cognitive impairment with characteristic neuropathological and neurochemical changes. The present a...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
牙齿脱落是老年人常见疾病,其中慢性牙周炎是引起牙齿脱落的主要原因。阿尔茨海默病是一种病因未明的常伴有认知功能损害的原发性退行性大脑疾病,具有特征性神经病理和神经化学改变。本文就牙齿脱落与阿尔茨海默病的相关性及相关机制等作一综述。.
zh-cn
pair_32842352
Tooth loss caused by trauma, periodontitis or inherited disorders severely affects human physical and mental health. As an essential part of the tooth, tooth root is connected to periodontal tissues to maintain the tooth in the alveolar socket. To figure out the molecular mechanisms regulating tooth root development wi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
牙体牙髓病、牙周炎、牙外伤和遗传性疾病等导致的牙齿缺失严重影响着人类的身心健康。牙根作为牙体组织的重要组成部分,通过与牙周组织的连接将牙齿固定于牙槽窝内。深入探究牙根发育的调控机制将有助于对牙根再生治疗新方法的探索。牙根发育是一个复杂的过程,涉及上皮和间充质组织间的交流以及多种信号通路的调控。本文就牙根发育过程中各信号通路作用的研究进展作一综述。.
zh-cn
pair_32842353
Magnetic resonance imaging is most frequently used for pre-surgical diagnosis and follow-up in salivary gland neoplasms. As for traditional techniques, dynamic contrast-enhanced and diffusion-weighted imaging are two magnetic resonance sequences commonly used in clinic, in spite of their relatively lower sensitivity an...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
唾液腺肿瘤是常见的唾液腺组织疾病,MRI是其术前诊断及术后随访中最常用的辅助检查手段。其中,传统的动态对比增强及弥散加权成像虽是目前临床普遍使用的MRI技术,然其敏感性与特异性并不高。近年来,一种全新的MRI扫描技术——酰胺质子转移MRI(amide proton transfer-MRI,APT-MRI),因其特殊的成像原理以及在人体多种肿瘤组织检测中所具有的较高的敏感性及特异性而备受关注;同时也有一些研究开始将这一新技术成功应用于唾液腺肿瘤的诊断及良恶性鉴别诊断中。本综述将重点围绕APT-MRI技术原理、APT-MRI与传统MRI技术在唾液腺肿瘤诊断中的优劣比较等内容展开,并基于APT-MRI技术在唾液腺肿瘤诊断中的初步应用提出...
zh-cn
pair_32842391
A 4-month-old child with skin rash for 2 days and fever for 1 day was hospitalized in the Department of Pediatrics of Erdos Central Hospital in November 2019. According to the clinical symptoms, medical history and medication history at the time of admission, it was diagnosed as urticaria with angioneuroedema. In this ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
患儿4月龄,因'皮疹2 d,加重伴发热1 d' 2019年11月就诊于鄂尔多斯市中心医院儿内科,根据入院时的临床症状、病史以及用药史,诊断为荨麻疹伴血管神经性水肿,并经实验室等检查排除其他病因后,考虑由药物对乙酰氨基酚引起,临床医师给予多种抗过敏药物(地氯雷他定、葡萄糖酸钙、维生素C),临床药师建议停用证据不足的维生素C与葡萄糖酸钙,仅用地氯雷他定抗过敏治疗,医师采纳并治疗5 d后好转出院。患儿使用对乙酰氨基酚3 d后出现荨麻疹,属于迟发性反应。.
zh-cn
pair_32842397
In recent 20 years, the technology of negative-pressure wound therapy (NPWT) has been widely used in the field of wound repair. Basic research and clinical application have proved that NPWT plays a positive role in regulating wound repair in many aspects. Compared with the previous 10 years, NPWT has made great progres...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
近20年来负压伤口疗法(NPWT)在创面修复领域广泛应用,基础研究和临床应用均证实其在多个方面对创面修复起正向调控作用。而近10年来,NPWT无论在负压材料或负压发生设备上的完善,还是在使用方法、作用机制研究以及临床应用策略方面,较之前的10余年都有了较大的进展。严格准确把握NPWT的临床应用指征,科学运用NPWT调控创面愈合微环境,有效改善各类型创面愈合质量,不断提升创面修复水平,是规范应用NPWT的核心要义。.
zh-cn
pair_32842407
From July 2018 to April 2019, 10 patients (8 males and 2 females, aged 5 to 53 years) who need skin grafting with 17 hands were admitted to the Fourth Medical Center of PLA General Hospital. The method of glove bandaging was used for wound hemostasis in skin grafting. After the initial hemostasis, sterile latex gloves ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2018年7月—2019年4月,解放军总医院第四医学中心收治10例需植皮的患者(男8例、女2例,年龄5~53岁),共17只患手,将手套包扎法用于植皮术中止血。术中初步止血后,以无菌乳胶手套作为手的内层覆盖物,再以纱布加压包扎,20 min后由近及远依次去除纱布和手套,再次彻底止血,最后植皮。手套作为内层覆盖物避免了纱布纤维与创面粘连,不会在打开包扎时造成小血管再次出血,减少了电凝的过度使用及对创面的二次损伤,减少失血量、缩短止血时间。.
zh-cn
pair_32842408
From June 2017 to October 2018, 7 patients with pressure ulcers were admitted to Taiyuan Ninth People's Hospital, including 3 males and 4 females, aged 75-86 years. There were totally 10 stage 4 pressure ulcer wounds without bone exposure, with wound area ranging from 6 cm×4 cm to 11 cm×9 cm. Three wounds were accompan...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2017年6月—2018年10月,太原市第九人民医院收治7例压疮患者,其中男3例、女4例,年龄75~86岁。共10个无骨外露4期压疮创面,创面面积为6 cm×4 cm~11 cm×9 cm;3个创面伴有潜行腔隙,潜行区域体表投影面积5 cm×3 cm~12 cm×8 cm。入院后进行保守清创治疗持续至皮肤缺损区肉芽组织鲜红、易出血、基底基本平整,于病床上取面积为创面大小1/4~1/2的大腿前侧刃厚皮片,制成微粒皮和/或边长1~3 mm的矩形小皮片,移植于肉芽创面,于术后继续保守治疗。7个创面1次移植术后3~6周愈合;1个创面1次移植术后6周潜行区仍残余窦道,患者出院;1个创面经2次移植,于第1次术后8周愈合。1例患者(1个创面)因基...
zh-cn
pair_32842409
On February 6, 2017, one male patient aged 25 years with total burn area of 99% total body surface area (TBSA) and full-thickness burn area of 95% TBSA was transferred from a primary hospital to the Second Affiliated Hospital of Zhejiang University School of Medicine one day post injury. On admission, the patient was c...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2017年2月6日,浙江大学医学院附属第二医院收治1例25岁烧伤总面积99%体表总面积(TBSA)男性患者。患者伤后1 d由基层医院转入,其中Ⅲ度烧伤面积达95%TBSA。入院时患者意识清楚,气管切开呼吸机辅助通气,实施补液抗休克、抗感染及营养支持,清创植皮负压治疗等处理。住院期间病情危重,先后行28次中心静脉置管术和1次经外周穿刺中心静脉导管置入术。护士依托多学科合作,在做好充分风险评估的前提下,重点加强中心静脉导管相关性感染的护理,导管尖端附着物、创面分泌物和血微生物培养检出抗碳青霉烯类抗生素肺炎克雷伯菌后,改良中心静脉导管护理措施。积极预防中心静脉导管周围血栓形成。在翻身床使用、浸浴治疗、患者躁动期间重点做好非计划性拔管的预防...
zh-cn
pair_32842410
On January 31, 2018, a 21-year-old male patient with extremely severe burn-blast combined injury complicated with acute kidney injury caused by dust explosion of crospovidone was admitted to the Second Affiliated Hospital of Zhejiang University School of Medicine. The following nursing measures were carried out, aiming...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2018年1月31日,浙江大学医学院附属第二医院收治1例交联聚维酮粉尘爆炸致特重度烧冲复合伤并发急性肾损伤的21岁男性患者。针对患者的病情,落实下列护理措施:烧伤休克期合并急性肾损伤行连续性肾脏替代治疗期间,加强液体出入量管理、防范低体温和非计划下机;针对创伤性气胸做好胸腔闭式引流管护理,实施低潮气量、低呼气末正压的通气策略;感染耐碳青霉烯类抗生素肺炎克雷伯菌期间优化监护室环境消毒、做好多黏菌素B药物护理。经过71 d综合治疗和护理,患者康复出院。本病例提示,针对特重度烧冲复合伤患者的肾功能、肺功能情况,实施个体化治疗和护理措施有助于提高该类患者的治愈率,并改善预后。.
zh-cn
pair_32842411
A female patient aged 42 years with deep burn on right lower limb was admitted to Affiliated Hospital of Jining Medical University on January 25, 2019. The patient previously had cerebral infarction, hypertension, and hysteria, with long-term use of aspirin and risperidone. After admission, the patient underwent tangen...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2019年1月25日,济宁医学院附属医院收治1例42岁女性右下肢深度烧伤患者,患者既往患有脑梗死、高血压、癔症等疾病,长期服用阿司匹林、利培酮。入院后先后2次行削痂手术,在第2次削痂植皮术后第3天出现右侧肢体肌力减弱,急诊行颅脑核磁共振成像,提示急性脑梗死,立即给予改善脑循环、扩血管等处理。术后第5天患者患肢肌力逐渐恢复,出院时未遗留后遗症。笔者团队对此病例进行讨论,认为深度烧伤削痂出血和术后创面渗出导致血容量降低、血液浓缩及不充分的补液导致脑血流动力学改变为主要诱因,多发脑动脉狭窄为基础,多种因素叠加,导致术后急性脑梗死的发生。术中及术后适当增加补液,必要时输血以增加脑部供血供氧,可减少此类脑梗死的发生。.
zh-cn
pair_32842412
One 24 years old female patient who suffered extremely severe burn in the third trimester of pregnancy was admitted to the Department of Burns and Skin Repair Surgery of the Third Affiliated Hospital of Wenzhou Medical University on 9th May, 2015. Intrauterine distress occurred after injury and stillbirth was confirmed...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2015年5月9日,温州医科大学附属第三医院烧伤与皮肤修复外科收治1例24岁妊娠晚期特重度烧伤女性患者。患者在伤后即出现胎儿宫内窘迫,于伤后第12 h确诊死胎,通过与产科医师合作,在伤后5 d引产成功。伤后8 d,患者出现脓毒症休克、多器官功能障碍综合征,经抗感染、呼吸机辅助通气、强心利尿、切削痂+皮片移植等治疗,患者最终痊愈。该病例提示把握适当时机、选择合理引产方式,果断处理死胎极其关键;休克期过后经阴道引产的方案,值得探讨;引产后24 h内极端、阵发的呼吸、循环及尿量变化为本例患者主要特点,动态关注并及时有效调整呼吸循环支持,有可能为该类患者救治的另一关键;尽可能抓住时机切削痂、覆盖异种皮,及时行皮肤移植修复创面则是重中之重。.
zh-cn
pair_32842413
On February 11, 2019, a 37-year-old female patient with neuromyelitis optica spectrum disorders was admitted to the Second Affiliated Hospital of Zhejiang University School of Medicine, and her acute osteomyelitis was caused by infection of multiple pressure ulcer wounds with <i>Staphylococcus aureus</i>. The patient w...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2019年2月11日,浙江大学医学院附属第二医院收治1例37岁的视神经脊髓炎谱系疾病女性患者,其因多处压疮创面感染金黄色葡萄球菌引起急性骨髓炎。对其进行多学科协作诊疗,护士重点做好激素减量治疗期间视神经脊髓炎谱系疾病症候群的严密观察,警惕病情反跳;根据诊疗方案,分阶段落实创面护理,保持有效引流,确保负压合适,加强营养以促进创面愈合。经过积极治疗和精心护理,患者于入院后第39天康复出院。.
zh-cn
pair_32842414
The scar contracture of Achilles tendon in burn patients after operation is easy to cause ' foot drop' , which leads to ankle dorsiflexion dysfunction. To solve this problem, the authors designed and made a static progressive ankle foot orthosis. The foot support part and the crus support part of the orthotic device ar...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
烧伤患者术后跟腱部位的瘢痕挛缩极易形成足下垂,导致踝关节背屈功能障碍。针对此问题,笔者自行设计、制作了一款静态进展性踝足矫形器。该矫形器足底支撑部分与小腿支撑部分由铆钉连接,两侧的牵拉带牵拉足底支撑部分远心端与小腿支撑部分近心端,从而循序渐进地改善踝关节背屈功能。此静态进展性踝足矫形器制作简单、实用性强、经济有效,值得临床推广。.
zh-cn
pair_32842415
Hyperpigmentation and hypopigmentation are complications commonly seen in burn patients after wound healing, which may have seriously adverse impact on the appearances of the patients. The change of skin color in the exposed areas such as the face and hands may cause great psychological burden on the patients. While th...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
色素沉着与色素脱失是烧伤患者创面愈合后的常见并发症,可严重影响患者外观,位于面部、双手等暴露部位的肤色改变,常给患者造成极大的心理负担。烧伤后色素沉着与色素脱失的发生发展机制尚不明确,一般认为与表皮中黑色素含量过多或缺失有关。因而在治疗上,前者侧重于抑制黑色素合成、减少皮肤黑色素含量,而后者则通过改善黑色素细胞功能、促进黑色素合成,进而恢复正常肤色。近年来,针对烧伤后皮肤色素代谢异常的治疗技术迅速发展,本文中笔者对临床常用的光电治疗、药物及手术治疗方案进行归纳总结,以期为此类患者的治疗提供参考。.
zh-cn
pair_32842416
Pain is one of the most common complications of burn patients. Burn from onset to rehabilitation is a long and complex process, during which dressing change, debridement, operation, and rehabilitation may cause different degrees of pain to the patients. As one of the means of non-pharmaceutical pain management, the int...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
疼痛是烧伤患者最常见的并发症之一,烧伤从发病到康复是一个漫长复杂的过程,其间伤口换药、清创、手术及康复等均会为患者造成不同程度的疼痛。虚拟现实技术作为非药物疼痛管理的手段之一,其干预效果已逐渐得到了越来越多研究者的认可。本文对虚拟现实技术的定义及其对疼痛的干预机制和烧伤疼痛中的干预效果进行综述,为虚拟现实技术在临床烧伤患者疼痛管理方面的应用提供参考。.
zh-cn
pair_32842417
Scar is a kind of skin fibroproliferative disease characterized by excessive repair of skin tissue and disorganized deposition of extracellular matrix resulting from deep dermal injury caused by burns or trauma. Scar is accompanied by symptoms such as itching and pain, which could lead to appearance damage and psycholo...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
瘢痕是由烧伤或创伤导致皮肤真皮深层损伤引起的皮肤组织过度修复、细胞外基质沉积紊乱的一种皮肤纤维增生性疾病,伴有瘙痒、疼痛等症状,可导致患者外观毁损和心理障碍,是烧伤整形外科门诊常见的病种之一。当前,脂肪组织及脂肪成分移植被认为是瘢痕最前沿的治疗方法之一。脂肪成分移植包括纳米脂肪、脂肪来源干细胞基质胶、基质血管成分和脂肪源性间充质干细胞移植。越来越多的研究显示,脂肪组织及脂肪成分具有组织再生、细胞外基质重塑和抗纤维化的功能,局部移植可改善瘢痕的外观及症状。因此,本文就脂肪组织及脂肪成分移植在瘢痕治疗中的作用作一综述,旨在为瘢痕的脂肪疗法提供理论参考。.
zh-cn
pair_32842418
Chitosan nanofibers are widely used in the field of wound dressings due to their excellent biocompatibility, antibacterial activity, and healing ability. One of the research directions in this field is to composite and modificate chitosan with other medical materials to prepare nanofiber composite materials and to stud...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
None
zh-cn
pair_32842419
The Wilderness Medical Society updated and published the <i>Wilderness Medical Society practice guidelines for the prevention and treatment of frostbite</i> in July 2019. The guidelines provide evidence-based recommendations for the prevention and treatment of frostbite, mainly including pathophysiology, classification...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
国际荒野医学协会于2019年7月更新并发布了《荒野医学协会冻伤预防和治疗实践指南》,该指南针对冻伤的预防和治疗提供循证推荐意见,主要包括冻伤的病理生理、分类、预防及治疗等内容。本文重点对该指南进行解读,旨在让临床医务人员了解冻伤治疗的新进展,为临床实践提供借鉴。.
zh-cn
pair_32842420
Malignant tumor-associated acute abdomen refers to a non-perioperative acute abdominal disease caused by malignant tumors or caused by various anti-tumor treatments with acute abdominal pain as the main clinical manifestation. It is often critical and even life-threatening. For patients with malignant tumor-associated ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
恶性肿瘤相关急腹症是指由恶性肿瘤导致、或者各种抗肿瘤治疗手段引发的以急性腹痛为主要临床表现的一种非围手术期腹部急性病变。往往病情急重、甚至威胁生命。患者一旦出现恶性肿瘤相关急腹症,肿瘤的发生发展与急性并发症的演变过程往往互为因果,故诊疗通常需要施行以外科为主的多学科诊治模式(MDT),及时地根据患者临床病理影像特征和医疗资源可及性,在肿瘤内、外科医生的主要参与下,与其他相关专业团队通力合作,根据不同的肿瘤学评估和治疗目标,通过分层管理,制定最适当的治疗策略。国内外对于恶性肿瘤相关急腹症诊治共识尚属空白。因此,中国医师协会外科医师分会、中国医师协会肿瘤医师分会、中国医师协会外科医师分会多学科综合治疗专业委员会联合《中华胃肠外科杂志》,...
zh-cn
pair_32842421
Presacral recurrent rectal cancer which involves the presacral fascia and/or sacral bone is one subtype of locally recurrent rectal cancer. Presacral recurrent rectal cancer is fixed posteriorly to the pelvis due to presacral fascial and/or sacral bone involvement, which makes treatment difficult. There is lack of stan...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
直肠癌骶前复发是直肠癌患者术后局部复发的解剖分型之一,为直肠癌根治性切除术后,骶前区域肿瘤复发,向后累及骶骨前方软组织及(或)骨性结构。直肠癌骶前复发因肿瘤累及骶前组织及(或)骨性结构,与盆腔存在固定关系,治疗难度较大。当前关于直肠癌骶前复发的诊断、治疗策略、手术方法等缺乏统一规范的诊疗流程。本共识旨在提高我国结直肠肿瘤临床医生对于直肠癌骶前复发的认识,以期规范直肠癌骶前复发的诊断和治疗策略。本共识围绕直肠癌骶前复发的诊断(临床症状、影像学和内镜检查、肿瘤标志物检测和病理活检)和治疗(放疗、化疗和手术治疗)以及随访和预后共提出17条直肠癌骶前复发诊疗相关的推荐意见。重点强调,经多学科协作团队(MDT)讨论评估后进行外科根治性手术干预...
zh-cn
pair_32842422
Presacral recurrent rectal cancer (PRRC) which involves the presacral fascia or/and sacral bone is one of the classification of locally recurrent rectal cancer. Presacral fascia or/and sacral bone involvement and posterior fixation make treatment difficult. In recent years, there are many researches on the diagnosis, s...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
直肠癌骶前复发是直肠癌局部复发的解剖分型之一,因肿瘤向后累及骶前软组织及(或)骨性结构,与盆腔存在固定关系,使得治疗难度增大,同时严重影响患者生活质量。随着直肠癌骶前复发诊疗的不断完善,外科治疗不断发展,手术方法不断创新,已形成了经多学科综合小组评估患者诊疗方案和以根治性手术为中心的直肠癌骶前复发综合治疗策略。经腹或腹会阴联合切除术、单纯骶骨切除术及腹骶联合切除术是目前治疗直肠癌骶前复发的常用术式;此外,其他治疗直肠癌骶前复发的术式还包括局限性骶骨切除术,但需严格把握其适应证。随着微创技术的发展,腹腔镜技术在直肠癌骶前复发中的应用也逐渐得到体现。综上述,直肠癌骶前复发的外科治疗已从早期的单一追求根治手术目标,到如今在实现根治性切除的...
zh-cn
pair_32842423
Presacral recurrence, a special recurrence type in rectal cancer after surgical treatment, refers to recurrent cancer invading the presacral soft tissue or the bony structure of sacrum. It is also a major constituent of recurrent rectal cancer (15.63% to 41.67%). Reports show that presacral recurrence rate is about 2.8...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
直肠癌骶前复发是直肠癌术后局部复发的一种特殊类型,指复发肿瘤累及骶骨前方软组织和(或)骶骨骨性结构。骶前复发是直肠癌局部复发的常见形式,占局部复发类型比例的15.63%~41.67%。根据文献报道,骶前局部复发率在2.8%~4.8%之间。直肠癌骶前复发与肿瘤临床分期、病理学类型、手术方式、(新)辅助放化疗、肿瘤距肛门距离、环周切缘阳性、淋巴结转移以及单侧侧方淋巴结清扫等临床因素有关。术后定期复查是早期发现直肠癌骶前复发的重要措施。CT和MRI的诊断是骶前复发的重要检查方法。骶前复发往往合并其他部位局部复发和远隔脏器转移,我们将骶前复发分为以下3种情况:(1)骶前复发合并远处转移;(2)骶前复发合并盆侧壁或侧方淋巴结转移、或其他脏器及...
zh-cn
pair_32842424
Imaging plays a key role in the diagnosis and decision-making process including pre-treatment planning, surgical strategy, and follow-up. The critical point in diagnosis of presacral recurrent rectal cancer by imaging modalities is to distinguish the recurrent tumor from nonmalignant tissues induced by operation or rad...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
影像检查在直肠癌骶前复发的诊断、术前治疗、手术策略和随访中发挥着关键作用。直肠癌骶前复发影像诊断的关键问题在于:骶骨及骶前区域肿瘤复发与术后及治疗后非肿瘤性病的鉴别。对于直肠癌复发患者,指南推荐CT作为密切随访影像检查方法。与之相比,MRI是诊断直肠癌复发包括骶前复发时更为准确的方法,诊断敏感性、特异性均高于CT检查。当CT或MRI存在诊断疑问时,正电子发射断层显像(PET)-CT可协助明确诊断且具备高敏感性和高特异性,但需要重视假阴性和假阳性。随访中通过影像动态观察骶前病变的变化是确定诊断的重要方法。除了影像学随访,还必须结合直肠癌原发灶治疗前肿瘤和淋巴结分期、高复发风险因素、治疗方法、手术术式、手术标本质量及术后病理分期等因素,...
zh-cn
pair_32842434
Fecal microbiota transplant (FMT) has become an effective method for the treatment of recurrent C. difficile infection. In addition, it has shown certain effects in other diseases inside and outside the intestine. A large number of clinical trials have been carried out. However, there is still lack of uniform standard ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
菌群移植(FMT)已成为治疗复发性艰难梭菌感染的有效手段,除此之外,在其他肠道及肠外疾病的治疗尝试中也显示出一定的效果,大量临床试验相继开展。关于FMT具体方法尚缺乏统一标准。本文从FMT适应证、供体筛选、菌液质量控制、FMT方法学、随访及疗效判断、不良反应处理以及伦理监管等方面,针对FMT目前存在的热点与争议问题,并结合本团队临床治疗经验做综合介绍。.
zh-cn
pair_32842435
Colorectal cancer is one of the most common malignant tumors of digestive tract. There are a large number of microorganisms in the digestive tract. Under normal physiological conditions, intestinal microorganisms can help with digestion and absorption, resist pathogen invasion and regulate the proliferation of intestin...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
结直肠癌是最常见的消化道恶性肿瘤之一。人体肠道内存在大量的微生物,正常生理状态下,肠道微生物将有助于肠道对食物的消化吸收,抵抗病原体入侵和调节肠道黏膜细胞的增殖;但肠道菌群失调会影响肠道内部微环境和肠道细胞功能,并且与结直肠癌的发病及疾病进展密切相关。本综述通过介绍结直肠癌患者肠道菌群的改变,从宏观层面总结肠道菌群参与结直肠癌发生的作用模式,并从细胞因子依赖性慢性炎性反应、肠道上皮细胞DNA损伤、肠道菌群代谢产物和细胞酶致癌,以及肠道内免疫系统的改变等几个方面总结肠道菌群参与结直肠癌发病的作用机制,为进一步研究结直肠癌的发病机制提供参考。最后,从肠道菌群治疗的角度,分析益生菌和菌群移植对于结直肠癌治疗的作用,为结直肠癌的治疗提供一些...
zh-cn
pair_32842436
Cancer immunotherapy, especially the programmed death 1 (PD-1) and (or) programmed death ligand 1 (PD-L1) checkpoint inhibitors, has ushered in the modern oncology era and has achieved impressive success in the treatment of different tumors, including non-small-cell lung cancer (NSCLC). Yet, only a subset of patients a...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
免疫治疗,尤其是程序性死亡受体1(PD-1)和(或)程序性死亡配体1(PD-L1)免疫检查点抑制剂,重塑了肿瘤治疗模式,在包括非小细胞肺癌(NSCLC)在内的多种肿瘤治疗中部分患者均获得了显著的临床获益。如何筛选PD-1和(或)PD-L1抑制剂潜在获益人群成为免疫治疗时代面临的新挑战。NSCLC中PD-L1蛋白表达水平与PD-1和(或)PD-L1抑制剂疗效呈正相关,是重要的预测标志物之一。明确PD-L1检测的临床意义和检测时机,在PD-L1检测步骤、结果判读和质量控制等各个环节实现PD-L1检测的规范化和标准化,对提高检测的准确性和降低室间差异具有重要意义。针对PD-L1检测的实际问题,在结合文献、专家经验和委员会成员内部讨论基础上...
zh-cn
pair_32842437
Stereotactic body radiation therapy (SBRT) has become an important radical approach for early stage non-small cell lung cancer, especially for patients who are inoperable or refuse surgery. In China, this precision radiotherapy technology is being popularized. In order to standardize clinical application, improve the c...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
立体定向体部放射治疗(SBRT)已成为早期非小细胞肺癌的重要根治性手段,尤其在不可手术或拒绝外科手术的患者中是首选治疗手段。在中国,SBRT正在普及,为了规范临床应用、推动技术水平提升和科研协作,特制定本专家共识。共识包括SBRT发展简介、物理技术要求、临床实施规范和特殊临床问题等,期望本共识在临床实践中可以为临床医师提供指导以及造福于广大肺癌患者。.
zh-cn
pair_32842438
The current situation of pancreatic cancer is that the etiology is not clear and prevention is difficult. The sensitivity and specificity of the auxiliary detection method are low, and early diagnosis is a worldwide problem. The efficacy of existing treatment method is not satisfied and is difficult to break through in...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
胰腺癌的病因尚未完全明确,预防便尤为困难。辅助检测手段的灵敏度和特异度低,早诊是世界性难题,现有的治疗手段疗效不满意,且短期内难以突破,总的5年生存率仅7.2%。面对胰腺癌的现状,要加强基础研究、探究其病因和发病机制,去除病因、切断发生发展路径。研发高灵敏度、高特异度的外周血和尿液等检测技术以及影像诊断技术以提高早期诊断率和疗效,但基础和早期诊断技术的研究时间长、费用高,短期内难以见效。因此,急需解决的问题是通过规范的多学科综合治疗(MDT)、优化组合现有的诊疗方法,制定个性化的治疗方案,达到改善疗效的目的。本共识是在第1版的基础上,基于胰腺癌的诊治现状且短期内难以突破的窘境,参照国际、国内成功的诊治经验,结合中国国情、由国内业界众...
zh-cn
pair_32842439
Bone is the second most common metastatic site of renal cell carcinoma (RCC), about 35-40% of metastatic RCC patients are associated with bone metastasis. Bone metastasis can cause pain, pathological fracture, spinal cord compression, hypercalcemia and other skeletal related events (SREs), which may seriously affect pa...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
骨转移为肾癌第2常见的转移部位,约35%~40%的转移性肾癌合并骨转移。可致疼痛、病理性骨折、脊髓压迫和高钙血症等骨相关事件(SRE),严重影响患者的生活质量。肾癌骨转移单纯药物治疗疗效有限,预后不佳,需采用多学科综合治疗模式,制定个体化的综合治疗方案,以减少或延缓SRE的发生,维持患者较好的生存质量,延长疾病控制和生存时间。为提高中国肾癌骨转移患者的规范化诊疗,恶性肿瘤骨转移和骨相关疾病临床诊疗专家组制定了肾癌骨转移专家共识(2020版)。.
zh-cn
pair_32842453
With the continuous development of cancer treatment, the immune checkpoint inhibitors have been applied to the treatment of a variety of malignant tumors, which improved the patient's survival time and quality of life. However, immune-related adverse reactions occur inevitably. Like chemotherapeutics and targeted drugs...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着恶性肿瘤治疗的不断发展,免疫检查点抑制剂已应用于多种恶性肿瘤的治疗,使患者的生存时间和生活质量有所改善,但在应用的过程中不可避免地发生免疫相关不良反应。与化疗药物和靶向药物相同,免疫抑制剂也会引起心血管事件,从而影响肿瘤患者的死亡率。随着肿瘤患者生存时间的延长,会日益成为影响这类疾病预后的关键因素。文章重点论述免疫检查点抑制剂在肿瘤治疗过程中引起的心脏毒性机制、临床表现以及未来发展方向。.
zh-cn
pair_32842720
Restricted cubic spline Cox proportional hazard regression model analysis is an important method of epidemiological multivariate survival analysis. By comparing the typical Cox regression model and the restricted cubic spline Cox regression model, this study expounds the limitations of the typical Cox regression model,...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
限制性立方样条Cox比例风险回归模型分析是流行病学多因素生存分析的重要方法。本研究通过对典型Cox比例风险回归模型和限制性立方样条Cox比例风险回归模型比较,阐述了典型Cox比例风险回归模型的局限性,以及限制性立方样条Cox比例风险回归模型基本原理与实现过程。在随访数据不满足典型Cox比例风险回归模型应用条件时,可采用该方法实现连续性暴露与结局之间的关联分析。.
zh-cn
pair_32843744
Herpes simplex keratitis (HSK) is a common, potentially blinding condition characterised by recurrent infections of the cornea, seen by both general ophthalmologists and corneal specialists. Successful treatment of recurrences reduces disease duration, prevents progressive corneal scaring leading to vision loss and red...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
摘要: 单纯疱疹病毒性角膜炎(herpes simplex keratitis, HSK) 是一种常见、潜在的致盲性疾病, 其特征是角膜反复感染, 普通眼科医生和角膜专家都可见到该病。成功治疗其反复发作可缩短病程, 防止进行性角膜瘢痕形成所导致的视力丧失以及降低进一步复发的风险。在这篇综述中, 我们讨论了实验室诊断包括聚合酶链反应、病毒培养及基于荧光的免疫组化的相对优势。我们对HSK在某些方面的治疗策略进行了回顾, 以及针对治疗无效病例的处理方案。.
zh-cn
pair_32844485
To investigate the impact of promising a referral bonus and an autonomous referral request on nurses' referral likelihood and the quality of their referrals. We applied a 2 × 2 between-participants factorial design with referral bonus and autonomous referral request as experimental variables. In May 2019, 110 nurses wo...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目标: 调查转荐奖金许诺和自主转荐要求对护士转荐可能性及转荐质量的影响。 设计: 我们采用2×2参与者间的因素设计,以转荐奖金和自主转荐请求作为实验变量。 方法: 2019年5月,110名在比利时医院工作的护士收到一封虚构的电子邮件,信中表明院方想要雇佣一些新员工,并让其填写一份线上调查,以衡量其转荐的可能性和质量。 结果: 转荐奖金许诺不影响护士转荐的可能性和质量。与自决权支持理论恰恰相反,自主转荐请求的护士比面对掌控请求的护士进行转荐的可能性更高,且转荐质量有保证。 结论: 医院可以通过自主支持方式确定转荐请求,藉此提高护士转荐的可能性和质量。 影响: 身处于当下新冠肺炎危机之中,招聘护士比以往任何时候都显得重要。我们的研究发现...
zh-cn
pair_32845537
The purpose of this exploratory, cross-sectional study was to identify child-related factors associated with maternal parenting stress in toddlers born very preterm and followed in a neonatal follow-up (NFU) clinic. The study aimed to describe the associations of current medical complications and presence of developmen...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
这项探索性的横断面研究是为了确认新生儿随访 (NFU) 门诊中早产儿母亲育儿压力的儿童关联因素, 旨在描述现有医疗并发症、发育迟缓症与总育儿压力之间的关系。研究对象是53对在NFU门诊中就诊的母婴二人组。母亲填写了“简式育儿压力问卷 (PSI-SF) ”, 儿童接受了“布里根斯早期启蒙筛选测验II”, 并从儿童的病历中收集了医学变量。研究显示约24%的母亲在“PSI-SF”中至少有一个较高的因子评分。回归分析表明, 早产儿母亲育儿压力的增加与其接受早期干预服务有关, 而不是由现有医疗并发症数量引起的。早产儿父母正面临着育儿压力增加的风险, 而这种压力超过了从新生儿重症监护室 (NICU) 出院时所承受的范围。NFU门诊的临床医生应去...
zh-cn
pair_32845537
The purpose of this exploratory, cross-sectional study was to identify child-related factors associated with maternal parenting stress in toddlers born very preterm and followed in a neonatal follow-up (NFU) clinic. The study aimed to describe the associations of current medical complications and presence of developmen...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Developmental and Medical Factors Associated with Parenting Stress in Mothers of Toddlers Born Very Preterm in a Neonatal Follow-Up Clinic Le but de cette étude d'exploration transversale était d'identifier des facteurs liés à l'enfant associés au stress de parentage maternel chez de jeunes enfants nés très avant terme...
fr
pair_32845537
The purpose of this exploratory, cross-sectional study was to identify child-related factors associated with maternal parenting stress in toddlers born very preterm and followed in a neonatal follow-up (NFU) clinic. The study aimed to describe the associations of current medical complications and presence of developmen...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Entwicklungs- und Gesundheitsfaktoren im Zusammenhang mit dem elterlichen Stress bei Müttern von frühgeborenen Kleinkindern in einer Neugeborenen-Nachsorgeklinik Das Ziel dieser explorativen Querschnittsstudie bestand darin, kindbezogene Faktoren zu identifizieren, die mit dem Stress von Müttern frühgeborener Kleinkind...
de
pair_32845537
The purpose of this exploratory, cross-sectional study was to identify child-related factors associated with maternal parenting stress in toddlers born very preterm and followed in a neonatal follow-up (NFU) clinic. The study aimed to describe the associations of current medical complications and presence of developmen...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
El propósito de este estudio exploratorio y transversal fue identificar factores relacionados con el niño, asociados con el estrés de crianza maternal en niños pequeñitos nacidos muy prematuramente en una clínica de seguimiento neonatal (NFU). El estudio se propuso describir las asociaciones entre las complicaciones mé...
es
pair_32845554
Dermatophytosis is a common problem in cattle. The aetiological factors associated with this disease are filamentous fungi with the ability to digest and grow on keratinized substrates. In cattle, and less frequently in other domestic animals and people, the dermatophyte Trichophyton verrucosum is most commonly isolate...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
背景-皮肤癣菌病是牛的常见问题。致病因素是丝状真菌,具有消化角质底物并在其上生长的能力。在牛身上,最常从皮肤病变中分离出的皮肤癣菌是疣状毛癣菌,这种情况也较少见于其他家畜和人。疣状毛癣菌这种皮肤癣菌菌是一种重要的人畜共患病原菌,主要传染源是豚鼠和其他小型啮齿动物。 目的-在本报告中,在长期运输和接种毛癣菌病疫苗后,我们发现了犊牛(普通牛) 的多种感染。 动物-进口的60头动物中,有32头在接种皮肤癣菌病疫苗后9-12天观察到浅表感染。 方法和材料-将临床体征与培养真菌的显微镜和肉眼检查联合诊断。使用分子分化确认种属。 结果-其中8头犊牛单独感染疣状毛癣菌,24头犊牛同时感染疣状毛癣菌和本哈米毛癣菌。我们认为,此次爆发的原因是运输和接...
zh-cn
pair_32845554
Dermatophytosis is a common problem in cattle. The aetiological factors associated with this disease are filamentous fungi with the ability to digest and grow on keratinized substrates. In cattle, and less frequently in other domestic animals and people, the dermatophyte Trichophyton verrucosum is most commonly isolate...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
La dermatophytose est fréquente chez le bétail. Les facteurs étiologiques associés sont des champignons filamenteux ayant la capacité de digérer et de croitre sur des substrats kératinisés. Chez le bétail et moins fréquemment dans d’autres espèces animales et chez l’homme, le dermatophyte Trichophyton verrucosum est pl...
fr
pair_32845554
Dermatophytosis is a common problem in cattle. The aetiological factors associated with this disease are filamentous fungi with the ability to digest and grow on keratinized substrates. In cattle, and less frequently in other domestic animals and people, the dermatophyte Trichophyton verrucosum is most commonly isolate...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Die Dermatophytose ist ein häufiges Problem bei Rindern. Die ätiologischen Faktoren, die mit dieser Krankheit in Zusammenhang stehen, sind filamentöse Pilze mit der Fähigkeit keratinisierte Substraten zu verdauen und in ihnen zu wachsen. Bei Rindern, und weniger häufig bei anderen Haustieren und beim Menschen wird der ...
de
pair_32845554
Dermatophytosis is a common problem in cattle. The aetiological factors associated with this disease are filamentous fungi with the ability to digest and grow on keratinized substrates. In cattle, and less frequently in other domestic animals and people, the dermatophyte Trichophyton verrucosum is most commonly isolate...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
A dermatofitose é um problema comum no gado. Os fatores etiológicos associados a esta doença são fungos filamentosos que possuem a habilidade de digerir queratina e crescer em substratos queratinizados. No gado, e menos frequentemente em outros animais domésticos e pessoas, o dermatófito Trichophyton verrucosum é o mai...
pt
pair_32845554
Dermatophytosis is a common problem in cattle. The aetiological factors associated with this disease are filamentous fungi with the ability to digest and grow on keratinized substrates. In cattle, and less frequently in other domestic animals and people, the dermatophyte Trichophyton verrucosum is most commonly isolate...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
La dermatofitosis es un problema frecuente en la ganadería. Los factores etiológicos asociados a esta enfermedad son los hongos filamentosos con capacidad de digerir y crecer sobre sustratos queratinizados. En el ganado, y con menos frecuencia en otros animales domésticos y personas, el dermatofito Trichophyton verruco...
es
pair_32847332
Prevention of blindness is of paramount importance for eye care and health care in China. In the past 70 years, we have embraced a lot of advancements in practice, manpower and landmark studies for the prevention of blindness and development of ophthalmic epidemiology. This summary is dedicated to our predecessors and ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
防盲治盲工作是健康中国和眼科事业的重要组成部分。本文回顾了我国防盲治盲和眼病流行病学工作70年历程,从无到有,防盲治盲水平不断提高,眼病流行病学工作全面开展,眼科队伍不断壮大发展,标志性研究成果不断涌现。希望以此缅怀前辈,激励后人,为我国眼科事业和防盲治盲工作的发展砥砺前行。谨以此文向全国防盲治盲和眼病流行病学工作者致敬,并祝贺《中华眼科杂志》创刊70周年。<i>(中华眼科杂志,2020,56:561-566)</i>.
zh-cn
pair_32847333
Carrying out research on infectious epidemics is an important work contents stipulated in the Law on the Prevention and Control of Infectious Diseases in China. Nowadays, Based on the recent Chinese prevention and treatment system of infectious eye diseases, it is difficult to meet the needs of data collection, etiolog...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
开展传染病的流行病学调查是我国传染病防治法中规定的重要工作内容。但我国目前传染性眼病防治体系对于当今高速发展、日趋复杂的社会模式,在数据采集、病因确定和时空分析等各方面都难以满足传染性眼病流行病学调查的需要。本文探讨了如何采用现代社会流行病学方法去明确个体因素、社会因素和结构因素对眼病流行的影响,采用空间流行病学方法去描述、定量和解释人群眼病流行的空间分布特点及发展变化规律,采用信息流行病学和数字流行病学方法去即时、高效地分析传染性眼病信息等,希望能为提升我国眼科流行病学的研究水平,完善我国传染性眼病防治工作提供新的思路。<i>(中华眼科杂志,2020,56:567-570)</i>.
zh-cn
pair_32847339
Fungal keratitis is an important cause of corneal blindness in China. Delayed diagnosis and treatment contribute to its poor prognosis. In recent years, with the advancement of laboratory test techniques, imaging diagnostic techniques and treatment methods, the diagnosis and treatment of fungal keratitis has constantly...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
真菌性角膜炎是我国角膜盲的重要原因,该病诊断困难、治疗棘手、预后较差。近年来,新的微生物实验室诊断技术和眼前节影像学分析方法不断出现并应用于临床,同时治疗方法也得到进一步改进,使得真菌性角膜炎的诊治水平明显提高。本文针对近年来真菌性角膜炎在实验室诊断、影像学诊断及药物治疗、手术治疗等方面上出现的新进展进行综述,以期促进这些新技术在我国真菌性角膜炎临床诊治过程中的应用。<i>(中华眼科杂志,2020,56:631-636)</i>.
zh-cn
pair_32851797
This study examined the association between quality of processes of diabetes care in terms of adherence to American Diabetes Association (ADA)-recommended guidelines and health care utilization in patients with diabetes. Adults with diabetes were identified from the pool of five panels of the Medical Expenditure Panel ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
背景: 这项研究调查了糖尿病患者遵循美国糖尿病协会(ADA)推荐指南的糖尿病护理过程质量与卫生保健使用情况之间的关系。 方法: 2012~2017年, 从具有全国代表性的美国医疗支出固定样本调查的五个合并样本中确定成年糖尿病患者。糖尿病护理调查被用来确定是否遵守ADA推荐的糖尿病护理流程指南, 前提是每年进行以下所有检查:糖化血红蛋白检查、足部检查、眼底检查、脂类检查、流感免疫接种、血压检查和牙科检查。在住院、急诊科和门诊就诊方面的卫生保健利用情况使用双栏模型进行估计。 结果: 根据汇集的5个样本数据大约2 630万成人糖尿病患者资料, 7.8%符合ADA推荐的糖尿病护理流程指南, 每条推荐建议的遵从率低于50%。总体而言, 遵守A...
zh-cn
pair_32852067
Indigenous Peoples' lands cover over one-quarter of Earth's surface, a significant proportion of which is still free from industrial-level human impacts. As a result, Indigenous Peoples and their lands are crucial for the long-term persistence of Earth's biodiversity and ecosystem services. Yet, information on species ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
原住民的土地占地球表面四分之一以上的面积, 其中有很大一部分尚未受到人类工业的影响。因此, 原住民及其土地对地球生物多样性和生态系统服务的长期续存至关重要。然而, 在全球范围内, 关于这些土地上物种组成的信息仍然很有限。我们根据国际自然保护联盟评估的 4460 种哺乳动物栖息地的数据, 首次对原住民土地上陆生哺乳动物的组成进行了全面分析。我们将每个物种的栖息地范围叠加在现有的原住民土地地图上, 发现 2695 个物种 (占已评估哺乳动物的 60%) 有 10% 以上的分布范围与原住民土地重合, 1009 个物种 (占 23%) 在原住民土地上的分布面积超过其栖息地面积的 50% 。受威胁物种中有 473 种 (占 47%) 在原住民...
zh-cn
pair_32852067
Indigenous Peoples' lands cover over one-quarter of Earth's surface, a significant proportion of which is still free from industrial-level human impacts. As a result, Indigenous Peoples and their lands are crucial for the long-term persistence of Earth's biodiversity and ecosystem services. Yet, information on species ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
La Importancia de las Tierras de los Pueblos Indígenas para la Conservación de los Mamíferos Terrestres Resumen Las tierras pertenecientes a pueblos indígenas cubren más de un cuarto de la superficie del planeta, una proporción importante que se encuentra aún libre de impactos humanos a nivel industrial. Como resultado...
es
pair_32852131
To evaluate the effectiveness of non-pharmacological interventions for eating difficulties in people with dementia (PWD). Eat difficulties are common problems in PWD. Prolonged eating difficulties may lead to inadequate/excessive food and drink intake and other adverse outcomes. Overview of systematic reviews. Cochrane...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目标: 评估痴呆患者(PWD)进食困难的非药物干预措施的有效性。 背景资料: 痴呆患者普遍存在进食困难的问题。长期的进食困难可能导致食物和饮料摄入不足/过量以及其他不良后果。 设计: 系统回顾概述。 数据来源: 考克兰图书馆、JBI循证护理中心图书馆、国际文献数据库(PubMed)、荷兰医学文摘数据库(Embase)、护理学数据库(CINAHL)、心理学文摘(PsycINFO)和心理学和行为科学丛书、中国期刊全文数据库(CNKI)、万方数据库(WANFANG)自成立之初至2019年9月23日的内容。 评审方法: 本概述根据考克兰方法学建议进行。两名研究人员根据纳入标准独立选择研究,提取数据,使用AMSTAR 2和GRADE系统评估符...
zh-cn
pair_32856344
Recovery of the antecedents and assumptions of Goffman's frame analysis to illustrate learning contexts in baccalaureate nursing programs. A discussion paper on the secondary analysis of focus group data. Focus group data collected in a multi-site study conducted in 2017 to understand the challenges of transitioning to...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目标: 恢复戈夫曼框架分析的前因和假设,以说明本科护理课程的学习环境。 设计: 关于焦点小组数据二次分析的讨论论文。 数据来源: 在2017年进行的多地点研究中收集的焦点小组数据,以了解黎巴嫩实践过渡中存在的挑战。本文以实证数据进行说明,但本文只是一篇概念性论文,而非一篇研究报告。 护理的启示: 向实践研究的过渡需要研究大学护理学院中的互动性,以检验课堂教学的意义。 方法: 阐明并使用戈夫曼基本框架、主线(故事线)、键控和重键控等概念,以描述学习环境的差异如何加大实践过渡的难度。 结论: 护理学士教育是将学生在大学学到的知识重新输入到理想的护理实践中。这一故事情节以课堂学习为主导,并重新融入了临床单元中主导学习环境的护理实践的实用方...
zh-cn
pair_32856353
This study aimed to evaluate the effect of the stress management interventional program in reducing occupational stress and improving coping strategies among public health nurses. A double-blind, cluster-randomized approach was used as a randomization method for this study to evaluate the stress management intervention...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目标: 本研究旨在探讨压力管理干预计划对降低公共卫生护士职业压力及优化应对策略的效果。 设计: 本研究采用双盲、集群随机方法,对压力管理干预方案进行评估。 方法: 在约旦安曼市的8个综合医疗中心进行了一项集群随机对照试验;每个实验组和对照组随机分配4个中心。从2019年3月至2019年8月,随机抽取170名护士,采用护理压力量表和简明应对量表进行三次数据收集。采用描述性和推断统计学(重复测量方差分析、独立t检验和卡方检验)来回答本研究中所研究的问题。 结果: 结果表明,在三个数据采集点上,两个研究组的职业压力水平和应对策略均存在显著差异(p<0.05)。 结论: 基于本研究结果,压力管理计划是一种有效的非侵入性方法,可用于降低公共卫...
zh-cn
pair_32857428
The aim of this study is to describe a longitudinal research protocol for exploring the relationship of dyadic appraisal, dyadic coping (DC), and dyadic mental health among stroke survivors and their spouses and its action path. Stroke can be considered as a dyad phenomenon which affects the mental health of both the s...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目标: 本研究旨在探讨中风存活者及其配偶之间的二元评估、二元应对(DC)和二元心理健康关系的纵向研究方案及其行为路径。 背景资料: 中风可以被认为是一种二元现象,影响幸存者及其配偶照护者的心理健康。需要基于二元理论的研究来检验二元评估和二元应对在中风二元患者心理健康中的作用。 设计: 纵向研究。 方法: 从医院招募病情稳定并即将出院的中风幸存者及其配偶照顾者。将在参与者出院后的3、6、9和12个月内进行随访评估。将使用结构方程模型进行统计分析。 讨论: 本研究试图扩展发展情境模型的理论,以检查变量之间的联系,包括应对中风夫妇的二元评价、二元应对和心理健康问题。.
zh-cn
pair_32857432
To analyse the effects of nurse-driven self-management (SM) programs on physical and psychosocial health variables in people with chronic obstructive pulmonary disease (COPD). A systematic review and meta-analysis. An exhaustive scanning of PubMed, Cochrane Controlled Register of Trials, CINAHL, ScienceDirect and Medli...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目标: 分析护士驱动的自我管理计划对慢性阻塞性肺疾病(COPD)患者身心健康变量的影响。 设计: 系统回顾和荟萃分析。 数据来源: 对国际文献数据库(PubMed)、Cochrane 临床对照试验中心注册数据库、护理学数据库(CINAHL)、期刊全文数据库(ScienceDirect)和联机医学文献分析和检索系统(MEDLINE)数据库2010年1月至2019年12月期间的文章进行详尽的扫描。 评审方法: 纳入慢性阻塞性肺病患者群体中与护士驱动的自我管理计划相关的随机对照试验(RCT)。确定主要变量的标准化平均差(95%置信区间),并用I2检验分析异质性。应用系统回顾和荟萃分析的首选报告项目(PRISMA)。 结果: 纳入12篇研究...
zh-cn
pair_32865351
Occlusal reconstruction aims to restore the compromised dentition and rehabilitate its function; which is demanding and challenging, even to the well experienced prosthodontists. Analyzing the sophisticate clinical information gives fundamental validity to the subsequent treatment planning. In the whole process, the ap...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
设计咬合重建不仅要恢复牙列的形态和美观,还要使重建的咬合关系与口颌系统的功能相协调;其诊断和治疗需要的知识面广,治疗过程的步骤多;即使对有相当经验的医师而言难度也很大。要达到良好的治疗效果,需要全面系统地分析临床信息,制定周密的治疗计划并精准地实施。在整个咬合重建的治疗过程中,有些关键问题对治疗的结果有重要影响,需要妥善解决,以便达到良好且稳定的长期临床效果。.
zh-cn
pair_32865353
To investigate the prognostic value of plasma miR-1290 in patients with oral squamous cell carcinoma (OSCC). Seventy patients with OSCC admitted to Danzhou People's Hospital from January 2014 to December 2018 were included in this study. Real-time fluorescence quantitative polymerase chain reaction (PCR) was used to de...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 探讨血浆miR-1290表达水平对口腔鳞状细胞癌(OSCC)患者预后预测的价值。方法 选取2014年1月—2018年12月儋州市人民医院收治的OSCC患者70例,采用实时荧光定量聚合酶链反应检测OSCC患者血浆miR-1290表达水平。通过ROC曲线确定血浆miR-1290表达水平的最佳界值,并以此为标准将OSCC患者分为高miR-1290组(n=31)和低miR-1290组(n=39),对2组临床病理特征进行比较。应用Kaplan-Meier法绘制生存曲线,采用单因素及多因素COX回归模型分析影响OSCC患者预后不良的危险因素。结果 OSCC组血浆miR-1290表达水平(0.65±0.14)明显低于对照组(2.06±0.9...
zh-cn
pair_32865352
To explore the association between two single nucleotide polymorphisms (SNPs), namely, rs4691383 and rs7667857, in the platelet-derived growth factor-C (PDGF-C) gene, the genotypes, environmental exposure factors, and nonsyndromic cleft lip with or without cleft palate (NSCL/P) in Western Chinese population. A total of...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 探究中国西部汉族人群血小板源性生长因子C(PDGF-C)基因的靶向单核苷酸多态性(SNPs)位点rs4691383、rs7667857及其基因型以及环境暴露因素与非综合征型唇腭裂(NSCL/P)发生的相关性。方法 收集268个NSCL/P病例—父母核心三人家系,采用聚合酶链反应—限制性酶切片段长度多态法和直接测序法对2个靶向SNPs位点(rs4691383、rs7667857)进行基因分型,使用哈温平衡检验、连锁不平衡检验、传递不平衡检验、单倍型关联分析等方法进行统计学分析。同时收集纳入对象所填写的唇腭裂流行病学研究问卷,对PDGF-C基因和环境暴露因素之间是否存在交互作用进行条件Logistic回归分析。结果 PDGF-C基...
zh-cn
pair_32865354
This study aimed to compare the effects of water storage treatment and thermal cycling on the shear bond strength (SBS) of three self-adhesive dual-cure resin cements. Six cubic zirconia specimens with side length of 2 cm were obtained by cutting and sintering. Three self-adhering dual-cure resin cements (i.e., Clearfi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 比较在水浴24 h及冷热循环5 000次条件下,氧化锆表面不同处理方式对自粘接双固化树脂水门汀剪切粘接强度(SBS)的影响。方法 切割烧结6个边长为2 cm的正方体氧化锆试件。采用3种自粘接双固化树脂水门汀(Clearfil SAC、RelyX U200、Multilink Speed)进行粘接,根据粘接方式分为直接粘接组(直接涂布树脂水门汀)、粘接剂组(应用与树脂水门汀搭配的通用型粘接剂后涂布树脂水门汀)、底涂剂组(应用底涂剂Z-Prime Plus后涂布树脂水门汀),每组又根据处理方式分为37 ℃恒温水浴24 h和冷热循环5 000次2个亚组。对各组试件进行SBS测试,采用SPSS 19.0软件进行单因素方差分析。利用体视...
zh-cn
pair_32865355
To investigate the clinical efficacy of a modified paramedian lower lip-submandibular approach for maxillary (subtotal) total resection. Eleven patients of maxillary tumors underwent maxillary (subtotal) total resection through the modified paramedian lower lip-submandibular approach. Clinical follow-up visits were con...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 探讨一种新的改良下唇旁正中-颌下入路在上颌骨(次)全切除术中的应用价值。方法 对11例上颌骨肿瘤患者采用改良下唇旁正中-颌下入路进行上颌骨(次)全切除术。术后对患者面形恢复、面神经及腮腺功能状态、眶区并发症等进行分析。结果 随访6~36个月,所有患者面形恢复良好,切口瘢痕隐蔽,均无面神经、腮腺导管损伤症状,也无下睑水肿、睑外翻、溢泪等眶区并发症。结论 改良下唇旁正中-颌下入路行上颌骨(次)全切除术可有效降低下睑水肿、睑外翻、溢泪等眶区并发症的发生率,且切口瘢痕隐蔽,未增加其他并发症的发生,值得临床推广。.
zh-cn
pair_32865356
To evaluate the effect of scaling and root planing (SRP) on serum C-reactive protein (CRP) levels in patients with moderate to severe chronic periodontitis. We searched the PubMed, Web of Science, EMBASE, Cochrane, CNKI, Wanfang, and VIP databases from the inception to July 8th, 2019. Two reviewers independently screen...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 探索牙周洁刮治(SRP)对中重度慢性牙周炎患者血清C反应蛋白(CRP)水平的影响。方法 检索PubMed、Web of Science、EMBASE、Cochrane、中国知网、万方数据库、维普数据库,检索时间截止2019年7月8日。由2名研究人员独立筛选文献、提取数据及评估偏倚风险。利用RevMan 5.3软件对数据进行Meta分析。结果 共纳入13篇临床随机对照试验,12篇前瞻性临床试验。Meta分析结果显示,与治疗前相比,SRP后2个月、3个月血清CRP水平降低(P<0.05),6个月时血清CRP水平差异无统计学意义(P=0.49)。结论 有限的证据表明,对于无系统性疾病的中重度慢性牙周炎患者来说,SRP治疗可以在短期内...
zh-cn
pair_32865357
To evaluate the effectiveness of periodontal endoscope as an adjuvant therapy for the non-surgical periodontal treatment of patients with severe and generalized periodontitis. Patients (n=13) were divided into three groups: patients treated with conventional subgingival scaling and root planing (SRP) (n=7, 408 sites) (...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 评估牙周内窥镜在辅助治疗年轻患者的重度广泛型牙周炎非手术治疗中发挥的作用。方法 观察了13例重度广泛型牙周炎患者738个位点,在经过牙周非手术治疗前后各项牙周指标的差异。根据所接受的治疗分为3组:A组龈下刮治术+根面平整术(SRP)治疗(n=7,408个位点);B组内窥镜辅助下行SRP治疗(n=4,188个位点);C组SRP治疗后3个月在内窥镜辅助下再次行SRP治疗(n=2,142个位点)。根据每个位点的基线PD值再将各组分为2个亚组:4<PD≤6 mm记为亚组1,PD>6 mm记为亚组2。记录各组的牙周探诊深度(PD)、附着丧失(AL)、牙龈退缩程度(GR)、探诊出血(BOP)。结果 治疗后3个月,A1组PD、AL和GR的改...
zh-cn
pair_32865358
To explore the correlation among gingival thickness (GT), underlying alveolar bone thickness (BT), and other periodontal biotype characteristics in the maxillary anterior. A total of 40 young volunteers with healthy periodontal were involved in this research. The periodontal probe was previously used to divide the ging...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 运用锥形束CT测量上颌前牙唇侧牙龈厚度与唇侧牙槽骨厚度,通过口内及模型测量牙冠宽长比、角化龈宽度、游离龈缘曲度,分析各牙周生物型特征之间的相关性。方法 选取40位牙周健康的青年志愿者,运用牙周探诊法预先判断受试牙位的牙龈厚薄,运用锥形束CT间接显影方法测量受试者上颌前牙区唇侧釉牙骨质界处牙龈厚度,以及牙槽嵴顶根方1、3、5 mm处牙槽骨厚度,通过口内及模型测量牙冠宽长比、附着龈宽度及游离龈缘曲度。结果 牙周探诊法区分的厚龈型与薄龈型间牙龈厚度的差异有统计学意义(P<0.01)。厚龈型(牙龈厚度≥1 mm)与薄龈型(牙龈厚度<1 mm)相应的牙周生物型特征之间的差异有统计学意义(P<0.05)。上颌前牙唇侧牙龈厚度与牙槽骨厚度呈...
zh-cn
pair_32865359
To observe the changes of forward displacement of maxillary complete denture during centric occlusion, three different methods were used to record the changes of vertical overlap and the comfort level of patients before and after the selective grinding of the three dentures made according to maxillo-mandibular horizont...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 通过观察3种方法确定水平颌位关系的全口义齿在选磨前及选磨后正中咬合时,上颌全口义齿近中移位的变化、前牙区覆牙合的变化及患者舒适度差异,探寻确定无牙颌水平颌位关系的最佳方法。方法 在适宜垂直距离条件下,对12例口颌系统基本正常的无牙颌患者同时制作由哥特式弓轨迹顶点、哥特式弓轨迹顶点前1 mm以及直接咬合法确定水平颌位关系的3副全口义齿(分别记作义齿A、B和C),记录每副全口义齿义齿选磨前及选磨后正中咬合时上颌全口义齿近中移位量、前牙区的覆牙合以及患者的舒适度,通过SPSS 17.0软件包对全口义齿近中移位量、前牙区的覆牙合变化量以及患者的舒适度进行统计学分析。结果 选磨前,义齿A的近中移位量最大,明显大于义齿B和义齿C(P<0....
zh-cn
pair_32865360
To understand the current cognition of acquired immunodeficiency syndrome (AIDS) occupational protection among the managers of multi-level stomatology medical institutions in efforts to provide a reference for formulating technical standards for occupational protection. Eighteen managers of oral medical institutions we...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 了解多层级口腔医疗机构管理者艾滋病职业防护认知现状,以期为制定适用于各口腔医疗机构的艾滋病职业防护技术标准提供参考依据。方法 采用质性研究中的现象学研究方法,对18名口腔医疗机构管理者就艾滋病职业防护相关问题进行半结构式、个体化深入访谈,并采用Nvivo 12.0软件对访谈资料进行编码、分析,提炼出主题。结果 共提炼出3个主题:各口腔医疗机构艾滋病职业防护措施主要从规范操作、标准预防及暴露后处理三方面进行,但防护措施落实不到位;各口腔医疗机构均会定期进行艾滋病职业防护培训,但未追踪培训效果;口腔医疗机构艾滋病职业防护管理中存在较多局限,主要包括缺乏特异性口腔艾滋病职业防护制度、口腔门诊患者艾滋病筛查难度高、艾滋病职业防护监管难...
zh-cn
pair_32865361
The effects of different tube currents and voltages on image quality and radiation dose were studied to provide a theoretical basis for low-dose cone beam computed tomography (CBCT) scanning in children. Different tube currents and voltages were used to scan the incisor area of fresh Bama pig heads by CBCT. The radiati...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 研究不同管电流、管电压对新鲜巴马猪猪头切牙区锥形束CT(CBCT)扫描时图像质量和辐射剂量的影响,为实现低剂量CBCT扫描提供理论依据。方法 将新鲜巴马猪猪头固定在CBCT扫描视野的中央,使用不同的管电流、管电压围绕切牙区进行360°扫描,记录辐射剂量,评价图像质量。结果 随着管电流或管电压的降低,辐射剂量逐渐下降,图像质量也逐渐下降。扫描参数90 kV、2.5 mA组合与60 kV、7.0 mA组合的平均容积CT剂量指数(CTDIvol)均为1.7 mGy,前者的图像质量评分高于后者,二者间差异具有统计学意义(P<0.05)。结论 在保证图像质量的前提下,降低管电流更能实现低剂量CBCT扫描。.
zh-cn
pair_32865362
To analyze the morphological changes in the upper airway of obstructive sleep apnea syndrome (OSAS) patients treated with oral appliance in skeletal class Ⅱ malocclusion with different vertical features by using cone beam CT (CBCT). Thirty-six patients diagnosed with OSAS by polysomnography and daytime sleepiness scale...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的 通过锥形束CT(CBCT)影像比较研究口腔矫治器治疗不同垂直骨面型的骨性Ⅱ类错牙合畸形伴阻塞性睡眠呼吸暂停综合征(OSAS)患者前后上气道三维形态变化。方法 采用口腔矫治器对多导睡眠监测仪及白天嗜睡量表诊断为OSAS且为骨性Ⅱ类错牙合畸形的36例患者进行治疗,戴用矫治器治疗4个月后,进行CBCT扫描分析不同垂直骨面型的OSAS患者治疗前后腭咽、舌咽等不同部位上气道形态的三维改变。结果 与治疗前相比,在戴用可调式矫治器4个月时,所有患者的腭咽容积测量值均显著增加(P<0.05);低角和均角患者的舌咽各项测量值均显著提高(P<0.05),高角患者的舌咽测量值中仅矢状向变化有显著差异,其余测量值变化的差异无统计学意义。结论 口腔治疗...
zh-cn
pair_32865363
Circular RNA, a non-coding RNA that forms a covalently closed continuous loop, exists widely in eukaryotic cells. The biogenesis and biological function of this type of RNA indicate that it can play a crucial role in diseases such as tumors, neural system diseases, and cardiovascular diseases; moreover, this RNA may ha...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
环状RNA(circRNA)是一种在真核生物中广泛存在的闭合环状非编码RNA,其生成机制、生物学功能的研究进展显示环状RNA可能在包括肿瘤、神经系统疾病、心血管疾病的发生发展过程中扮演重要角色,具有作为疾病标志物的潜能。口腔鳞状细胞癌(OSCC)是口腔外科最常见的恶性肿瘤之一,具有难治疗、易转移、预后差等的特点,由于其发生机制尚不明确,从基因层面阻断OSCC尚不能实现。而环状RNA在OSCC领域的研究进展将为OSCC的生物治疗带来新的思路。本文归纳综述了环状RNA的成环机制、生物学功能及在肿瘤尤其是OSCC发展中的研究进展。.
zh-cn
pair_32865364
Oral cancer is the most common malignant tumor in the head and neck, and is one of the world's top ten malignancies. Microbial infection is an important risk factor of oral cancer. Candida albicans is the most popular opportunistic fungal pathogen. Epidemiological studies have shown that Candida albicans is closely tie...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
口腔癌是头颈部最常见的恶性肿瘤,也是全世界十大最流行的恶性病损之一。口腔微生物感染是口腔癌重要的危险因素。白色念珠菌作为口腔最常见的机会性致病真菌,大量流行病学资料证实,白色念珠菌感染与口腔黏膜恶变存在密切联系,而相关动物实验也证实,白色念珠菌感染能促进上皮癌变。现有研究表明,白色念珠菌可能的促癌机制涉及破坏上皮屏障、产生致癌物质(包括亚硝胺、乙醛)、诱导慢性炎症反应、激活免疫反应等。然而,目前关于这些机制的深入研究还不够充分,一些假说尚存在一定的争议。因此,本文就目前白色念珠菌对口腔黏膜疾病恶性转化作用的相关研究成果作一综述,为进一步的研究和临床口腔癌的防治工作提供参考。.
zh-cn
pair_32865365
Noncarious cervical sclerotic lesions (NCSL) are dental cervical lesions with noncarious sclerotic dentine (NCSD), which appears smooth, hard, and either light yellow or dark brown. Most NCSLs are wedge or dish shaped and commonly occur in canines and premolars, leading to dental hypersensitivity and aesthetic defect. ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
牙颈部非龋性硬化性病损(NCSL)是含有非龋性硬化性牙本质(NCSD)的牙颈部病损,大多数呈楔状或碟形,表面光亮,质硬,呈淡黄色或深棕色,好发于尖牙以及前磨牙,临床上可伴牙本质敏感,并影响美观。
目前,治疗NCSL的主要方法是复合树脂直接粘接修复,但存在充填体脱落率高等临床问题。NCSL的粘接界面
有NCSD和釉质2个部分,研究表明粘接修复前对这该界面进行特殊处理可以提高NCSL的粘接性能。本文对NCSL直接粘接修复术的表面处理方法及其对粘接性能的影响作一综述,为临床治疗提供参考。.
zh-cn
pair_32865366
Ankyloglossia is a congenital condition characterized by a short lingual frenulum, which may result in the restriction of tongue movement and function. Considerable controversy regarding the diagnosis, clinical significance, and management of the condition remains, and great variations in practice have been recorded. I...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
舌系带过短是一种先天性异常,可能会限制舌尖的活动能力,削弱舌的功能,然而对舌系带过短的诊断、临床表现、治疗存在的争议历史已久。不仅不同专业群体对舌系带过短的态度不同,甚至在同一专业的人之间观点也不同。本文对舌系带过短的胚胎学、遗传学、诊断、临床表现、治疗作一综述,以帮助各科医师更好地认识和治疗舌系带过短。.
zh-cn
pair_32865367
Oral squamous cell carcinoma (OSCC) is a common malignant tumor in the oral and maxillofacial region. At present, the treatment of OSCC is mainly based on surgical oriented comprehensive sequence therapy, especially the triple therapy of surgery, radiotherapy, and chemotherapy. However, the overall five-year survival r...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
口腔鳞状细胞癌(OSCC)是一种常见的口腔颌面部恶性肿瘤,目前对于OSCC的治疗主要是以手术为主的综合序列治疗,但5年生存率仍不高。因此,对OSCC发病机制及治疗的研究就显得极其重要。免疫检查点程序性死亡受体-1(PD-1)和程序性死亡受体-1配体(PD-L1)是近年来的研究热点,大量研究表明PD-1/PD-L1在多数OSCC微环境中高表达,有助于实现肿瘤的免疫逃逸。本文对PD-1/ PD-L1及其抑制剂在OSCC中的研究现状进行综述。.
zh-cn
pair_32865368
Severe congenital neutropenia is a rare disorder characterized by a consistently low absolute neutrophil count and periodontal disease. This report describes the case of an ELANE mutationin a patient with gingival bleeding and tooth mobility. Oral examination showed active periodontal infection of the primary dentition...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
重型先天性中性粒细胞缺乏症是一种罕见的外周血中性粒细胞绝对计数减少的疾病,常伴有全口牙周组织的损害。本文报道1例ELANE基因突变导致的重型先天性中性粒细胞缺乏症患儿严重的牙周病损,患儿因全口牙松动、刷牙出血前来就诊,口腔检查为全口乳牙活跃性牙周病损伴后牙区牙槽骨广泛性吸收,经多学科会诊,1年后确诊为重型先天性中性粒细胞缺乏症。该患儿追踪3年,经过全身系统性疾病治疗和有效的口腔健康宣教及维护,在一定程度上缓解了牙周损害。.
zh-cn
pair_32865369
Osteonecrosis of the jaw could occur after intake of bisphosphonate drugs, which are widely used to treat osteoporosis and bone metastasis of malignant tumors. This effect has aroused concern among dentists. In this paper, a case of bisphosphonate-related osteonecrosis caused by implant is reported, and the pathogenesi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着双膦酸盐类药物在骨质疏松、恶性肿瘤骨转移等方面的广泛应用,不断有颌骨坏死发生的报道,已逐渐引起口腔医生的高度关注。本文报道1例种植体植入术后引起双膦酸盐相关性颌骨坏死的病例,并结合相关文献阐述双膦酸盐类药物性颌骨坏死的发病机制、诊断、预防及治疗方法,进一步讨论使用双膦酸盐后对种植体的影响。.
zh-cn