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pair_25378758 | The World Health Organization is developing the 11th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-11), planned for publication in 2017. The Working Group on the Classification of Sexual Disorders and Sexual Health was charged with reviewing and making recommendat... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Всемирная организация здравоохранения разрабатывает 11-ю редакцию <i>Международной статистической классификации болезней и проблем, связанных со здоровьем</i> (МКБ-11), которую планируется опубликовать в 2017 году. Рабочей группе по классификации сексуальных расстройств и сексуальному здоровью было поручено рассмотреть... | ru |
pair_25378759 | Despite seven years of investment from the President's Emergency Plan For AIDS Relief (PEPFAR), the expansion of human immunodeficiency virus (HIV)-related services continues to challenge Mozambique's health-care infrastructure, especially in the country's rural regions. In 2012, as part of a national acceleration plan... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 尽管获得总统防治艾滋病紧急救援计划(PEPFAR)七年的投资,莫桑比克的医疗基础设施依然面临着扩大艾滋病毒(HIV)相关服务的挑战,在该国的农村地区尤其如此。 在2012年,作为全国性HIV护理和治疗加速计划的组成部分,纳玛库拉(Namacurra)地区采用移动诊所策略来提供临时人力和物理空间,以扩大四个农村外围诊所的服务。本文介绍了在开始18个月的实施过程中部署的战略、提供的服务和吸取的关键经验教训。 2012年,纳玛库拉成年人口估计为125425人,其中估计有15803人受到艾滋病毒的感染。虽然始终有抗逆转录病毒疗法(ART)项目的政府支持,但是这种治疗的全国覆盖率仍然很低,到2012年12月,有资格获得这种治疗的人群中仅有不到... | zh-cn |
pair_25378759 | Despite seven years of investment from the President's Emergency Plan For AIDS Relief (PEPFAR), the expansion of human immunodeficiency virus (HIV)-related services continues to challenge Mozambique's health-care infrastructure, especially in the country's rural regions. In 2012, as part of a national acceleration plan... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Malgré les 7 années d'investissement du Plan d'urgence du Président des États-Unis d'Amérique pour la lutte contre le SIDA (PEPFAR), l'expansion des services de lutte contre le virus de l'immunodéficience humaine (VIH) est toujours un défi pour les infrastructures de soins de santé du Mozambique, en particulier dans le... | fr |
pair_25378759 | Despite seven years of investment from the President's Emergency Plan For AIDS Relief (PEPFAR), the expansion of human immunodeficiency virus (HIV)-related services continues to challenge Mozambique's health-care infrastructure, especially in the country's rural regions. In 2012, as part of a national acceleration plan... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | A pesar de los siete años de inversión del Plan de Emergencia del Presidente de los Estados Unidos de América para luchar contra el SIDA (PEPFAR), la expansión de los servicios relacionados con el virus de la inmunodeficiencia humana (VIH) continúa suponiendo un desafío para la infraestructura sanitaria de Mozambique, ... | es |
pair_25378759 | Despite seven years of investment from the President's Emergency Plan For AIDS Relief (PEPFAR), the expansion of human immunodeficiency virus (HIV)-related services continues to challenge Mozambique's health-care infrastructure, especially in the country's rural regions. In 2012, as part of a national acceleration plan... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Несмотря на инвестиции, которые в течение семи лет выделялись в рамках Чрезвычайного плана Президента США по борьбе со СПИДом (PEPFAR), распространение услуг по борьбе с вирусом иммунодефицита человека (ВИЧ) продолжает оставаться проблемой для инфраструктуры здравоохранения Мозамбика, особенно в сельских регионах стран... | ru |
pair_25378760 | In 2010, dengue virus (DENV) serotype-4 was detected during a dengue outbreak in the Amazonian city of Boa Vista. At that time Brazil was already endemic for DENV-1, DENV-2 and DENV-3. This was the first time DENV-4 was observed in the country after it was initially detected and eliminated in 1981. To hinder the spread... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 2010年在亚马逊河城市博阿维斯塔爆发登革热期间检测到登革热病毒(DENV)血清分型-4。当时,巴西已经发生了DENV-1、DENV-2和DENV-3地方病。这是继1981年最初检测并消灭DENV-4之后,首次在该国发现DENV-4。 为防止DENV-4在巴西的全面蔓延,加强了标准病媒控制措施。病媒控制专业人员走访了博阿维斯塔31个区中22个区的56 837户家庭,以消除蚊虫孳生地点。使用杀幼虫剂二氟脲处理储水容器,喷洒溴氰菊酯对付成年埃及伊蚊。十五天后,执行第二次幼虫调查,并施用额外的溴氰菊酯。 巴西在所有三个政府层面进行登革热病媒控制的管理。每年进行四到六次埃及伊蚊定期监测,以便加强病媒密度高地区的蚊虫活动控制。社区中教育性的登... | zh-cn |
pair_25378760 | In 2010, dengue virus (DENV) serotype-4 was detected during a dengue outbreak in the Amazonian city of Boa Vista. At that time Brazil was already endemic for DENV-1, DENV-2 and DENV-3. This was the first time DENV-4 was observed in the country after it was initially detected and eliminated in 1981. To hinder the spread... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | En 2010, le sérotype-4 du virus de la dengue (DENV) a été détecté pendant une épidémie de dengue dans la ville amazonienne de Boa Vista. À l'époque, le Brésil était déjà endémique pour les sérotypes DENV-1, DENV-2 et DENV-3. C'était la première fois que le sérotype DENV-4 était observé dans le pays après avoir été init... | fr |
pair_25378760 | In 2010, dengue virus (DENV) serotype-4 was detected during a dengue outbreak in the Amazonian city of Boa Vista. At that time Brazil was already endemic for DENV-1, DENV-2 and DENV-3. This was the first time DENV-4 was observed in the country after it was initially detected and eliminated in 1981. To hinder the spread... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | En el año 2010 se detectó el serotipo 4 del virus del dengue (DENV) durante un brote de dengue en la ciudad amazónica de Boa Vista. En aquel momento, en Brasil ya eran endémicos los serotipos DENV-1, DENV-2 y DENV-3. Tras su detección inicial y eliminación en 1981, esta fue la primera vez que se volvía a observar el DE... | es |
pair_25378760 | In 2010, dengue virus (DENV) serotype-4 was detected during a dengue outbreak in the Amazonian city of Boa Vista. At that time Brazil was already endemic for DENV-1, DENV-2 and DENV-3. This was the first time DENV-4 was observed in the country after it was initially detected and eliminated in 1981. To hinder the spread... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | В 2010 году, во время вспышки лихорадки денге в городе Боа-Виста в бассейне реки Амазонки, был обнаружен вирус денге 4-го серотипа (DENV-4). К этому времени Бразилия уже являлась эндемичной по серотипам DENV-1, DENV-2 и DENV-3. Серотип DENV-4 наблюдалсяв страневпервыепосле первоначального выявления и ликвидации в 198... | ru |
pair_29860756 | The initiation of tumor is a complex process with multi-factor participation, particularly the activation of oncogenes and/or inactivation of tumor suppressor genes. Long non-coding RNAs (lncRNAs) play important roles in tumorigenesis. Additionally, as a metabolic process in cells, autophagy also contributes greatly to... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 肿瘤的发生是一个多因素参与的复杂过程,通常与癌基因的激活或抑癌基因的失活有关。长链非编码RNA(lncRNA)在肿瘤的形成过程中发挥了重要的生物学作用,而自噬作为细胞内的一种代谢过程,也在肿瘤细胞分化、转移及耐药等方面扮演了重要角色,成为近年来的研究热点。深入研究和了解lncRNA与自噬的关系以及具体作用机制,有助于揭示肿瘤发生、发展,为肿瘤的诊断和治疗提供新的思路。. | zh-cn |
pair_29860791 | The first national surveillance of COPD in mainland China was carried out in 2014, with the nationally representative data obtained. The national surveillance was significantly important for the monitoring of prevalence, risk factors, and changing trend of COPD among Chinese adults aged ≥ 40. The surveillance was also ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 2014年我国开展了中国居民COPD监测,获得全国代表性数据结果。COPD监测对于掌握中国≥40岁居民COPD患病及其危险因素的流行状况与变化趋势,制定国家COPD防控政策,评估防控效果,建立COPD综合监测系统以及建设专业的COPD监测与防控队伍具有重要意义。本期重点号文章介绍了COPD监测的方法与内容,报告了中国≥40岁人群肺功能检查率及COPD知识知晓率,分析了该人群的烟草烟雾暴露、职业粉尘暴露、生物燃料和煤燃料暴露等主要COPD危险因素的流行状况,以及COPD高危人群分布特征,为我国开展COPD综合防控工作提供了基础数据。. | zh-cn |
pair_29860792 | COPD refers to a group of chronic respiratory diseases which seriously influence the people's health and life quality. The national COPD surveillance in China has been implemented since 2014 with the goal of monitoring the prevalence and trend of COPD and related risk factors in China. The paper summarizes the item and... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | COPD是一类严重影响我国居民健康和生活质量的慢性呼吸系统疾病。2014年中国开展COPD监测项目,旨在掌握≥40岁居民COPD患病情况以及相关影响因素的流行和变化趋势。本文将对'中国居民COPD监测项目'内容和方法进行简要介绍。. | zh-cn |
pair_29860821 | The era of medical big data, translational medicine and precision medicine brings new opportunities for the study of etiology of chronic complex diseases. How to implement evidence-based medicine, translational medicine and precision medicine are the challenges we are facing. Systems epidemiology, a new field of epidem... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 医学大数据、转化医学、精准医学时代为慢性复杂疾病及其病因的研究带来新的契机。如何实现循证医学、科学转化、合理精准是我们目前面临的任务和挑战。系统流行病学是一种进行疾病危险因素风险识别的流行病学方法,是流行病学的新领域,其利用系统生物学、流行病学、计算数学等技术将健康大数据与系统生物学结合起来,在分子、细胞、组织、人群社会行为和生态环境等多水平、多组学上深入研究疾病发生风险的统计学模型,并对未来风险状况进行计算模拟和预警预测。由于数据来源的多样性、复杂性以及大数据的特征,为系统流行病学的设计方法和分析方法提出了新的挑战。本文详细介绍了系统流行病学的理论基础、概念、研究目的、研究内容、研究意义、研究设计、分析方法及其在公共卫生领域的应用... | zh-cn |
pair_29860822 | Lead time bias might exist in observational study for clinical outcomes. This paper summarizes the concept of lead time bias, causes and control of lead time bias by using the studies of influences of screening diagnostic test on cancer patients'survival and highly active antiretroviral therapy on HIV/AIDS patients' su... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 临床结局观察性研究中可能存在领先时间偏倚。本文以筛检诊断试验对肿瘤患者生存时间的影响研究、高效抗反转录病毒治疗对HIV/AIDS生存时间的影响研究,两个实例阐述领先时间偏倚的概念、产生原因及控制,为准确分析评价检测、治疗等干预措施对存在多个疾病病程或分期疾病的作用效果时提供控制该偏倚的思路和方法。. | zh-cn |
pair_29874716 | Chinese Medicine, being one of the most creative disciplines, with the superiority of its disciplinary theory and thinking pattern closely related to the studies of Sinology.Chinese Medicine has taken on its great aspect with good favorable prospects of timing, geographical and unity and coordination of human relations... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 中医学是最具原创优势的学科之一,其学科理论、思维方式与国学密不可分。中医学迎来了天时、地利、人和的大好局面,中医学的发展首先要认清其原创优势,理清其原创思维的来源。象思维是中国传统思维的本质内涵和基本特征,显示了中华民族文化的特殊品格,中医原创思维当与象思维紧密链接。西方文化的传入压抑了原发创生性的象思维,惟科学主义的概念思维与西医成为了主流。其实应该既不排斥概念思维,又要注重表达自己民族特有的原创思维及原创优势,东学西学兼收并蓄,中医西医融通共进。. | zh-cn |
pair_29874718 | In Gao Ruone's epitaph written by Wen Yanbo, it was mentioned that Gao studied medicine because of his mother's diseases, reflecting his filial piety as a Confucianist. It was recorded that 'more <i>Yun</i> people engaged in medical profession, especially proficient at treating cold damage diseases, and all followed Ga... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 在文彦博为高若讷撰写的《墓志铭》中,高若讷因母病而知医,体现了作为'儒者'的'孝'的一面。叶梦得《避暑录话》云:'郓人多医,尤工伤寒,皆本高氏',《宋史·高若讷传》进一步演绎为'名医多出卫州,皆本高氏学'。同时,高若讷被黄庭坚视为从黄帝、岐伯至张仲景以来,医学知识传承脉络中的重要一环。究其原因在于高若讷曾考校'张仲景《伤寒论诀》、孙思邈《方书》及《外台秘要》',使其得以流传,宋人也因此而知晓这些方书。宋人对高若讷记述的变化,突显了宋人对医学文本阅读在医学知识传承中重要作用的认同。. | zh-cn |
pair_29874719 | In traditional society, medical charity had strong moral and educational purposes. But this pursuit of morality faded away in modern times. As to the charity purpose, unlike the medical charity organizations that were eager to rebuild the morality and public ethics, instead, more and more interests were paid to utilita... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 传统社会中,救济贫病、施医给药的善举有着浓重的道德教化色彩。近代以降,民间医疗慈善的道德诉求日渐式微。从施善目的来看,医疗慈善组织不再像传统社会追求重塑社会道德与公众价值伦理,而是有着更多的功利性考量和世俗利益诉求于其中;从施善社会功能来看,此时的'病'者,不再被视为'贫'的延伸,而是作为最直接的救助指标;医疗行为变得更为单纯,在实践上向着更专业化的方向发展,在一定程度上促进了近代医疗体系的诞生;医疗慈善超越单纯的道德教化,被视为救国策略和社会改造的重要途径,体现出强烈的国家责任与政治意图。. | zh-cn |
pair_29874720 | The Mogan Mt.Sanatorium for Pulmonary Tuberculosis, founded in 1927, was the first tuberculosis sanatorium in modern China, with an initial intention of 'treating and caring the diseased, not seeking profits' , and its name was then changed to Mogan Mountain Sanatorium in 1931. During the early period of Anti-Japanese ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 莫干山肺病疗养院是近代中国成立最早的肺病疗养院,以'救济疾病,不杂营利观念'为初衷,成立于1927年,后于1931年更名为莫干山疗养院。抗日战争初期,疗养院成为难民避难所,并开展慈善救济。1939年5月,因日军飞机轰炸,疗养院被迫关停,后于1948年正式复业,并延续至今。莫干山疗养院的患者以政要、富商、文人雅士为主要群体;以天然疗养和药物治疗并重,并注重精神关怀;疗养院的经费源于疗养收费、患者资助、庚子赔款和名人字画展览等;疗养院借助广告,报告业务扩展与医务人员变更、宣传疗效以吸引患者。作为20世纪初的新事物,疗养院的出现是人们卫生观念增强、健康意识提高与主权意识觉醒的产物。. | zh-cn |
pair_29874721 | To encourage the collection and improve of purchase are the important measures to solve the shortage of Chinese medicine. In 1958, due to the large amount of rural manpower invested in the campaign of construction of water conservancy projects and the large-scale steel-making and iron-smelting, the planting of traditio... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 鼓励采集与改善收购,是解决中药材短缺的重要措施。1958年由于农村劳动力大量投入水利工程建设和大炼钢铁,导致中药种植减少和'药荒' 。为缓解中药材短缺的严重局面,国务院继1958年发出利用和收集野生植物原料的指示后,于1959年提出开展'小秋收' ,将野生中药材的采收纳入其中。此后20年间,广泛动员采收野生中药材的'小秋收' ,一直是解决中药材短缺的主要途径,为缓解中药材供应紧张问题发挥了重要作用。. | zh-cn |
pair_29875515 | To assess the magnitude of the Mexican epidemic of Zika virus infection and the associated risk of microcephaly. From the reported number of laboratory-confirmed symptomatic infections among pregnant women and the relevant birth rate, we estimated the number of symptomatic cases of infection that occurred in Mexico bet... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 旨在评估墨西哥寨卡病毒的感染率以及相关的头小畸型风险。. 据报告,经实验室确诊出现症状的孕妇感染案例数和相关出生率,我们估计了 2015 年 11 月 25 日(首例报告确诊的墨西哥案例)至 2016 年 8 月 20 日之间在墨西哥发生的出现症状的感染案例量。我们采用了出生证明上的数据以比较寨卡病毒传入前(2010 年 1 月 1 日至 2015 年 11 月 30 日)后(2015 年 12 月 1 日至 2017 年 9 月 30 日)先天性头小畸型平均每月的发病率,并根据母亲的居住地是否至少位于海拔 2200 米的高度上对数据进行分层。我们采用了间断泊松时间序列、统计建模和图像分析。. 我们对 2015 年 11 月 25 ... | zh-cn |
pair_29875515 | To assess the magnitude of the Mexican epidemic of Zika virus infection and the associated risk of microcephaly. From the reported number of laboratory-confirmed symptomatic infections among pregnant women and the relevant birth rate, we estimated the number of symptomatic cases of infection that occurred in Mexico bet... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Évaluer l'ampleur de l'épidémie d'infections à virus Zika au Mexique et estimer le risque associé de microcéphalie. En utilisant le nombre de cas signalés, confirmés en laboratoire, d'infections symptomatiques de femmes enceintes et le taux de natalité correspondant, nous avons fait une estimation du nombre de cas symp... | fr |
pair_29875515 | To assess the magnitude of the Mexican epidemic of Zika virus infection and the associated risk of microcephaly. From the reported number of laboratory-confirmed symptomatic infections among pregnant women and the relevant birth rate, we estimated the number of symptomatic cases of infection that occurred in Mexico bet... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Evaluar la magnitud de la epidemia de infección del virus Zika y el riesgo asociado de microcefalia en México. Del número de infecciones sintomáticas reportadas en laboratorio entre mujeres embarazadas y la tasa de nacimiento relevante, estimamos el número de casos de infección sintomática que ocurrieron en México entr... | es |
pair_29875515 | To assess the magnitude of the Mexican epidemic of Zika virus infection and the associated risk of microcephaly. From the reported number of laboratory-confirmed symptomatic infections among pregnant women and the relevant birth rate, we estimated the number of symptomatic cases of infection that occurred in Mexico bet... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Оценить масштабы эпидемии инфекции, вызываемой вирусом Зика, в Мексике и связанный с ней риск микроцефалии. На основе количества зарегистрированных, лабораторно подтвержденных случаев симптоматической инфекции среди беременных женщин и соответствующего коэффициента рождаемости авторы установили число случаев симптомати... | ru |
pair_29875516 | To provide a comprehensive overview of poisoning mortality patterns in China. Using mortality data from the Chinese national disease surveillance points system, we examined trends in poisoning mortality by intent and substance from 2006 to 2016. Differences over time between urban and rural residents among different ag... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 旨在全面综述中国中毒死亡概况。. 我们采用《中国疾病监测系统死因监测数据集》,根据意图和物质分类研究了 2006 年至 2016 年间的中毒死亡趋势。我们分别针对男性和女性采用了负二项模型,对不同年龄段城市和农村居民及中毒的外部原因随着时间的差异变化进行了量化。. 在 2016 年,84 060 559 人的样本中共有 4936 人中毒死亡(每 100 000 人中有 5.9 人;95% 置信区间:5.6–6.2)。2006 至 2016 年间,年龄标准化中毒死亡率从每 100 000 人中有 9.2 人降至 5.4 人。男性、农村居民和老年人群的中毒死亡率始终高于女性、城市居民和儿童或青壮年人群的中毒死亡率。大部分与杀虫剂有关的自... | zh-cn |
pair_29875516 | To provide a comprehensive overview of poisoning mortality patterns in China. Using mortality data from the Chinese national disease surveillance points system, we examined trends in poisoning mortality by intent and substance from 2006 to 2016. Differences over time between urban and rural residents among different ag... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Offrir un aperçu détaillé des schémas de mortalité par empoisonnement en Chine. À partir de données sur la mortalité provenant du système national chinois à points pour la surveillance des maladies, nous avons examiné les tendances de la mortalité par empoisonnement, suivant les intentions et les substances, de 2006 à ... | fr |
pair_29875516 | To provide a comprehensive overview of poisoning mortality patterns in China. Using mortality data from the Chinese national disease surveillance points system, we examined trends in poisoning mortality by intent and substance from 2006 to 2016. Differences over time between urban and rural residents among different ag... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Ofrecer una visión general integradora de los patrones de mortalidad por intoxicación en China. Utilizando datos de mortalidad del sistema nacional chino de puntos de vigilancia de enfermedades, examinamos las tendencias en la mortalidad por intoxicación con intención y fundamento de 2006 a 2016. Se cuantificaron las d... | es |
pair_29875516 | To provide a comprehensive overview of poisoning mortality patterns in China. Using mortality data from the Chinese national disease surveillance points system, we examined trends in poisoning mortality by intent and substance from 2006 to 2016. Differences over time between urban and rural residents among different ag... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Предоставить всесторонний обзор показателей смертности в результате отравления в Китае. Используя данные о смертности, полученные из национальной системы эпиднадзора Китая, авторы изучили тенденции смертности в результате отравления по фактору преднамеренности и по отравляющему веществу с 2006 по 2016 год. Динамика раз... | ru |
pair_29875517 | To describe a crowdsourced disease surveillance project (EpiCore) and evaluate its usefulness in obtaining information regarding potential disease outbreaks. Volunteer human, animal and environmental health professionals from around the world were recruited to EpiCore and trained to provide early verification of health... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 旨在描述众包疾病监测项目 (EpiCore) 并评估其在获取潜在疾病突发信息方面的有用性。. 从世界各地招募人类、动物和环境卫生方面的专业人员志愿者至 EpiCore,并且通过安全、易于使用的在线平台让志愿者在其所处的地理区域接受培训,从而提供公共卫生威胁警报的早期证实。新兴传染病领域的专家向这些志愿者发出针对尚未证实卫生威胁的信息请求,这些志愿者得以运用其对当地情况的了解和专业知识,对相应请求做出回应。专家对这些回应进行审查和归纳,同时通过现有基于事件的疾病监测网络——ProMED,将重要信息迅速传播至全球卫生社区。. 2016 年 3 月至 2017 年 9 月,来自 142 个国家的 2068 名 EpiCore 志愿者接受了... | zh-cn |
pair_29875517 | To describe a crowdsourced disease surveillance project (EpiCore) and evaluate its usefulness in obtaining information regarding potential disease outbreaks. Volunteer human, animal and environmental health professionals from around the world were recruited to EpiCore and trained to provide early verification of health... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Décrire un projet participatif de surveillance des maladies (EpiCore) et évaluer son utilité pour obtenir des informations sur d'éventuelles flambées épidémiques. Des professionnels bénévoles de la santé humaine, animale et environnementale du monde entier ont été recrutés dans le cadre du système EpiCore. Ces professi... | fr |
pair_29875517 | To describe a crowdsourced disease surveillance project (EpiCore) and evaluate its usefulness in obtaining information regarding potential disease outbreaks. Volunteer human, animal and environmental health professionals from around the world were recruited to EpiCore and trained to provide early verification of health... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Describir un proyecto de control de enfermedades con participación pública (EpiCore) y evaluar su utilidad para obtener información sobre potenciales brotes de enfermedad. Se reunieron a profesionales de salud humana, animal y medioambiental de todo el mundo para el proyecto EpiCore y se capacitaron para proporcionar v... | es |
pair_29875517 | To describe a crowdsourced disease surveillance project (EpiCore) and evaluate its usefulness in obtaining information regarding potential disease outbreaks. Volunteer human, animal and environmental health professionals from around the world were recruited to EpiCore and trained to provide early verification of health... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Описать проект для наблюдения и контроля заболеваний (EpiCore), организованный по принципу краудсорсинга, и оценить его практическую ценность в получении информации о потенциальных вспышках заболеваний. Компанией EpiCore со всего мира были на добровольных началах набраны специалисты по охране здоровья человека, животны... | ru |
pair_29875518 | To examine the empirical basis for including the diagnostic category of 'a single episode of harmful substance use' in the 11th revision of the <i>International statistical classification of diseases and related health problems</i> (ICD-11). We used data on patients admitted to emergency departments in 21 countries wit... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 旨在调查将“有害物质使用的单次发作”诊断类别纳入第 11 版《疾病和有关健康问题的国际统计分类》(ICD-11) 的经验基础。. 我们运用来自 21 个国家因饮酒致伤(即饮酒后 6 个小时之内)而进入急诊部的患者数据。根据第 10 版《疾病和有关健康问题的国际统计分类》(ICD-10) 的描述,这些患者无酒精中毒或者戒断迹象、血液中无酒精、无酒精依赖症或者有害饮酒的迹象。我们获取有关酒精相关伤害、患者饮酒致伤的因果归因、摄入的酒精量、血液中的酒精浓度和通常饮酒模式的数据。我们对有无酒精依赖症或者是否为有害饮酒的患者进行了对比。. 我们纳入了 18369 份患者样本。对不等概率抽样进行整理后,18.8% 的患者称受伤之前 6 个小时内... | zh-cn |
pair_29875518 | To examine the empirical basis for including the diagnostic category of 'a single episode of harmful substance use' in the 11th revision of the <i>International statistical classification of diseases and related health problems</i> (ICD-11). We used data on patients admitted to emergency departments in 21 countries wit... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Examiner les conditions empiriques de l'inclusion de la catégorie de diagnostic «épisode isolé de consommation nocive de substances» dans la 11<sup>e</sup> révision de la Classification internationale des maladies et des problèmes de santé connexes (CIM-11). Nous avons utilisé des données relatives à des patients admis... | fr |
pair_29875518 | To examine the empirical basis for including the diagnostic category of 'a single episode of harmful substance use' in the 11th revision of the <i>International statistical classification of diseases and related health problems</i> (ICD-11). We used data on patients admitted to emergency departments in 21 countries wit... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Examinar las bases empíricas para incluir la categoría diagnóstica de 'episodio único de consumo de sustancia nociva' en la undécima revisión de la <i>Clasificación internacional de enfermedades y problemas relacionados con la salud</i> (CIE-11). Utilizamos datos de pacientes admitidos en salas de emergencia en 21 país... | es |
pair_29875518 | To examine the empirical basis for including the diagnostic category of 'a single episode of harmful substance use' in the 11th revision of the <i>International statistical classification of diseases and related health problems</i> (ICD-11). We used data on patients admitted to emergency departments in 21 countries wit... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Изучить эмпирическую основу для включения диагностической категории «единичного эпизода употребления вредных веществ» в 11-ю редакцию <i>Международной классификации болезней и проблем, связанных со здоровьем</i> (МКБ-11). Авторы использовали данные о пациентах, поступивших в отделения неотложной помощи в 21 стране с тр... | ru |
pair_29875519 | To examine the potential for international travel to spread yellow fever virus to cities around the world. We obtained data on the international flight itineraries of travellers who departed yellow fever-endemic areas of the world in 2016 for cities either where yellow fever was endemic or which were suitable for viral... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 审核黄热病病毒通过国际旅行在全球各城市传播的可能性。. 我们获取了相关旅客国际航班线路的行程信息。这些旅客于 2016 年从全球黄热病流行区出发前往各个城市。这些目的地城市要么是黄热病流行区,要么是病毒易感区。我们运用登革热病毒传播的全球生态模型预测非病区城市的黄热病易感性。我们获取了旅客抵达的目的地城市针对黄热病疫苗接种的入境要求信息。. 2016 年,4520 万搭乘国际航班的旅客从全球黄热病流行区出发。其中,1170 万旅客的目的地位于 472 个非黄热病流行区的城市,但这些城市属于病毒易感区,770 万 (65.7%) 的旅客在抵达时并未被要求提供疫苗接种证明。巴西、秘鲁、墨西哥、美国、印度和中国拥有最多来自黄热病流行区的旅... | zh-cn |
pair_29875519 | To examine the potential for international travel to spread yellow fever virus to cities around the world. We obtained data on the international flight itineraries of travellers who departed yellow fever-endemic areas of the world in 2016 for cities either where yellow fever was endemic or which were suitable for viral... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Évaluer la capacité des déplacements internationaux à propager le virus de la fièvre jaune dans des villes du monde entier. Nous avons recueilli des données sur les itinéraires de vols internationaux de voyageurs qui quittaient des zones d'endémie de la fièvre jaune à travers le monde en 2016 pour se rendre dans des vi... | fr |
pair_29875519 | To examine the potential for international travel to spread yellow fever virus to cities around the world. We obtained data on the international flight itineraries of travellers who departed yellow fever-endemic areas of the world in 2016 for cities either where yellow fever was endemic or which were suitable for viral... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Examinar el potencial de los viajes internacionales de propagar el virus de la fiebre amarilla en ciudades de todo el mundo. Se obtuvieron datos de los itinerarios de vuelo internacionales de viajeros que partieron de áreas endémicas de la fiebre amarilla en el mundo en 2016 hacia ciudades donde la fiebre amarilla era ... | es |
pair_29875519 | To examine the potential for international travel to spread yellow fever virus to cities around the world. We obtained data on the international flight itineraries of travellers who departed yellow fever-endemic areas of the world in 2016 for cities either where yellow fever was endemic or which were suitable for viral... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Изучить потенциальное влияние международных поездок на распространение вируса желтой лихорадки в городах по всему миру. Авторы получили данные о маршрутах международных перелетов путешественников, которые в 2016 году отправлялись из районов мира, эндемичных по желтой лихорадке, для тех городов, где желтая лихорадка не ... | ru |
pair_29875520 | If universal health coverage (UHC) is to be achieved globally, it needs sustained promotion and political awareness and support. During its presidency of the Group of Seven (G7) industrialized nations in 2016, Japan aimed to raise the issue of UHC to the top of the global health agenda. Japan has promoted a health agen... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 如果要在全球范围内实现全民健康覆盖 (UHC),需持续推进工作、提高政治意识,并获得政策支持。. 在 2016 年担任七国集团轮值主席国期间,日本致力于将全民健康覆盖 (UHC) 问题提到全球医疗卫生发展议程的首要位置。. 自 2000 年以来,日本在历届七国集团 (G7) 峰会期间均提出了医疗卫生议程。数十年来,人类安全问题一直是日本外交政策的核心基石。因此,将全民健康覆盖 (UHC) 列入 2016 年七国集团峰会议程时,日本国内并未出现明显的反对声音。其他七国集团 (G7) 成员国也积极促进此项事业的发展。. 自 2016 年七国集团峰会以来,尽管联合国和世界卫生组织的领导者不断更迭,但全民健康覆盖 (UHC) 始终是这两大全... | zh-cn |
pair_29875520 | If universal health coverage (UHC) is to be achieved globally, it needs sustained promotion and political awareness and support. During its presidency of the Group of Seven (G7) industrialized nations in 2016, Japan aimed to raise the issue of UHC to the top of the global health agenda. Japan has promoted a health agen... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Une promotion durable ainsi qu'une prise de conscience et un soutien politiques sont indispensables pour parvenir à une couverture sanitaire universelle à l'échelle mondiale. En 2016, dans le cadre de sa présidence du Groupe des sept pays les plus industrialisés (G7), le Japon s'est proposé de mettre la question de la ... | fr |
pair_29875520 | If universal health coverage (UHC) is to be achieved globally, it needs sustained promotion and political awareness and support. During its presidency of the Group of Seven (G7) industrialized nations in 2016, Japan aimed to raise the issue of UHC to the top of the global health agenda. Japan has promoted a health agen... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Si se pretende lograr una cobertura sanitaria universal (CSU) en el mundo, se necesitan la promoción sostenida, y la conciencia y el apoyo políticos. Durante su presidencia en 2016 del Grupo de los Siete (G7) formado por las 7 naciones industrializadas, Japón se propuso elevar el tema de la CSU hasta el primer puesto d... | es |
pair_29875520 | If universal health coverage (UHC) is to be achieved globally, it needs sustained promotion and political awareness and support. During its presidency of the Group of Seven (G7) industrialized nations in 2016, Japan aimed to raise the issue of UHC to the top of the global health agenda. Japan has promoted a health agen... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Для обеспечения всеобщего охвата медико-санитарными услугами на глобальном уровне необходимо постоянное содействие, политическая осведомленность и поддержка. В период своего председательства в группе промышленно развитых стран «Большой семерки» (G7) в 2016 году Япония поставила перед собой задачу поднять вопрос о всеоб... | ru |
pair_29875521 | Urbanization, large dog populations and failed control efforts have contributed to continuing endemicity of dog-mediated rabies in KwaZulu-Natal province, South Africa. From 2007 to 2014 we used a OneHealth approach to rabies prevention, involving both the human and animal health sectors. We implemented mass vaccinatio... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 城市化进程、大量的狗群以及无效的控制工作导致犬类介导的狂犬病在南非共和国夸祖鲁纳塔尔省内持续流行。. 2007 年至 2014 年,我们使用了同一健康 (OneHealth) 方法研究狂犬病预防,其涉及人类和动物健康领域。为了控制狗群中的狂犬病,我们实施了大规模疫苗接种运动,同时采取了一些策略来提高公众对狂犬病的认识并为接触狂犬病的人群提供接触后的预防措施。. 狂犬病流行区——夸祖鲁纳塔尔省是南非共和国面积最小、人口最多的省份之一(估计人口为 10 900 000)。自 1976 年传入以来,狂犬病一直持续存在。1976 年至 2007 年本项目开始,夸祖鲁纳塔尔省每年平均发生的人类狂犬病病例为 9.2 例。. 2007 年至 20... | zh-cn |
pair_29875521 | Urbanization, large dog populations and failed control efforts have contributed to continuing endemicity of dog-mediated rabies in KwaZulu-Natal province, South Africa. From 2007 to 2014 we used a OneHealth approach to rabies prevention, involving both the human and animal health sectors. We implemented mass vaccinatio... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | L'urbanisation, les importantes populations canines et les mesures de lutte inefficaces ont contribué à l'endémicité persistante de la rage transmise par les chiens dans la province du KwaZulu-Natal, en Afrique du Sud. De 2007 à 2014, nous avons appliqué l'approche «Un monde, une santé» pour la prévention de la rage, e... | fr |
pair_29875521 | Urbanization, large dog populations and failed control efforts have contributed to continuing endemicity of dog-mediated rabies in KwaZulu-Natal province, South Africa. From 2007 to 2014 we used a OneHealth approach to rabies prevention, involving both the human and animal health sectors. We implemented mass vaccinatio... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | La urbanización, las grandes poblaciones de perros y los esfuerzos fallidos de control han contribuido a la continuación de la transmisión de la rabia por perros en la provincia de KwaZulu-Natal, Sudáfrica. De 2007 a 2014, se utilizó un enfoque «Una salud» para la prevención de la rabia, que involucraba a los sectores ... | es |
pair_29875521 | Urbanization, large dog populations and failed control efforts have contributed to continuing endemicity of dog-mediated rabies in KwaZulu-Natal province, South Africa. From 2007 to 2014 we used a OneHealth approach to rabies prevention, involving both the human and animal health sectors. We implemented mass vaccinatio... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Урбанизация, большие популяции собак и неудачные попытки контроля способствовали сохранению эндемичности по бешенству, переносимому собаками, в провинции Квазулу-Наталь, Южная Африка. С 2007 по 2014 год авторы использовали подход OneHealth к профилактике бешенства, включающий секторы здравоохранения как людей, так и жи... | ru |
pair_29883221 | The study aims to investigate the body composition and bone mineral density (BMD) characteristics and discuss the relationships among body composition, BMD and sex steroid level in POF. A total of 240 POF patients, 240 normal women, and peri/postmenopausal women (Peri-M/Post-M) (260 patients in each group) were include... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 摘要 本研究旨在探讨体成分和骨密度(BMD)特征, 并探讨POF患者体成分、骨密度和性类固醇水平之间的关系。共纳入240名POF患者、240名正常女性和围绝经期/绝经后女性(Peri-M/Post-M)(每组260名患者)。与对照组相比, POF患者左/右下肢力量(SLL/SRL)、下肢肌肉分布系数(MD)下降, 腰围(WC)和臀围(HC)增加。POF患者的体重、WC、HC、全身脂肪百分比(BF%)、平均脂肪分布(FD)、MD均低于Peri-M和Post-M;BMD均低于Peri-M, 即便如此, 仍高于Post-M。此外, BMD与BF%、FD、SLL、MD和雌二醇(E2)显著正相关。与L2-L4 BMD相关的因素是E2、SRL、... | zh-cn |
pair_25800567 | It has been proven that cancer stem cell existed in variety of cancer, which an significant difference of biological characteristics was observed between the cancer stem cells and non-cancer stem cells. And CD133 is considered to be cancer stem cell marker. So there may be significant differences in CD133- positive cel... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 背景与目的 研究表明多种实体肿瘤中存在肿瘤干细胞(cancer stem cells, CSCs),肿瘤干细胞与非肿瘤干细胞的生物学特性存在已有的明显差异,而CD133被认为是肿瘤干细胞的标记物,因此CD133阳性细胞与CD133阴性细胞可能存在明显差异。本研究通过分选人肺腺癌A549细胞中的CD133阳性及CD133阴性细胞,鉴定两组细胞的生物学特性并在人组织标本进行验证,利用基因芯片筛选转移相关差异基因。方法 采用磁式分选(magnetic activated cell sorting, MACS)的方法对人肺腺癌A549中CD133阳性细胞、CD133阴性细胞进行分选,通过无血清条件培养、平板克隆、血清诱导分化及基因芯片等实验... | zh-cn |
pair_25800571 | Mediastinal involvement in lung cancer is a highly significant prognostic factor for survival, and accurate staging of the mediastinum will correctly identify patients who will benefit the most from surgery. Positron emission tomography/computed tomography (PET/CT) has become the standard imaging modality for the stagi... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 背景与目的 肺癌纵隔淋巴结转移是非常重要的生存预后因素,准确的纵隔分期可以使患者最大程度地受益于手术,正电子发射体层显像/计算机体层成像(positron emission tomography/computed tomography, PET/CT )已成为肺癌患者分期的常规手段。本研究旨在探讨18氟-氟代脱氧葡萄糖(18-fluoro-2-deoxy-glucose, 18F-FDG )PET/CT在判断肺癌纵隔淋巴结转移上的价值。方法 回顾性分析72例肺癌患者术前全身PET/CT显像结果。72例患者均行根治性手术及系统纵隔淋巴结清扫,共取出413枚淋巴结,其中转移淋巴结为45枚。以病理结果作为标准,测量淋巴结短径、CT值、标准... | zh-cn |
pair_25800573 | Studies on combined small cell lung cancer (C-SCLC), which shows continuously increasing incidence, are rare. Accordingly, we explored the relationship between the clinicopathological characteristics and prognostic factors of C-SCLC patients and analyzed the treatment of this disease. Between January 2006 and December ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 背景与目的 复合型小细胞肺癌(combined small cell lung cancer, C-SCLC)的检出率逐年增高,但其相关报道仍较少,本研究探讨C-SCLC的临床病理特征与预后的关系,分析其治疗现状。方法 回顾性分析2006年1月-2011年12月间80例病理证实的C-SCLC患者的资料,采用Kaplan-Meier法计算生存率,Log-rank法进行单因素预后分析,Cox风险回归模型分析影响总生存(overall survival, OS)的因素。结果 全组的OS为0.3个月-81.4个月,中位OS为26.2个月。单因素分析显示:性别、治疗前卡氏评分、肿瘤直径、分期是影响OS的预后因素(P<0.05)。多因素分析显示... | zh-cn |
pair_25800576 | Cancer cells exhibit altered glucose metabolism characterized by a preference for aerobic glycolysis even when the oxygen content is normal, a phenomenon termed 'Warburg effect'. However the definite molecular mechanisms of Warburg effect remains unclear, recent works indicated that it might be related to the abnormal ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 肿瘤细胞葡萄糖代谢的一个特点就是在氧含量正常的情况下依然选择利用糖酵解,即Warburg效应。Warburg效应的内在机制十分复杂,可能与癌基因激活、抑癌基因失活,糖代谢酶表达异常和肿瘤微环境改变等有关,具体的机制还有待进一步研究。Warburg效应这种代谢重编程与肿瘤的发生发展有着密切联系,为肿瘤细胞提供生长优势,帮助其逃避凋亡,同时为肿瘤的转移创造合适的环境,促进肿瘤转移。本文概述了Warburg效应的发生机制及其对肿瘤转移的作用。. | zh-cn |
pair_25800577 | Human epididymis 4 (HE4) belongs to whey acidic 4-disulfide center protein family. It has the characteristics of inhibiting trypsin and high expression in the serum or malignant pleural effusion of patients with lung cancer. Clinical data showed that it has certain relevance to the diagnosis and prognosis of lung cance... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 人附睾蛋白4(human epididymis 4, HE4)属于乳清酸性4-二硫化中心(WFDC)蛋白家族,具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达,现有临床数据显示它与肺癌的诊断及预后有一定的相关性,因此可能成为临床上肺癌的诊断及预后评估的新指标。. | zh-cn |
pair_34636194 | Oxygen is an essential molecule for animal respiration, growth, and survival. Unlike in terrestrial environments, contamination and climate change have led to the frequent occurrence of hypoxia in aquatic environments, thus impacting aquatic animal survival. However, the adaptative mechanisms underlying fish responses ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 氧气是影响动物呼吸、生长和生存的重要环境因子。与陆地环境不同,水生环境受污染和气候变化等因素的影响,低氧现象频发,进而影响水生动物的生存。然而,迄今为止,鱼类应对环境低氧的适应机制尚未探明。该研究中,我们以大黄鱼( <i>Larimichthys crocea</i>)和大黄鱼仔鱼(LYCF)细胞为研究对象探讨了Hif-1α/Hsf1/Hsp70信号通路在调节细胞氧化还原稳态和细胞凋亡中的作用。结果显示,体内及体外低氧模型中,低氧诱导了大黄鱼Hif-1α、Hsf1及Hsp70的表达; <i>Hsp70</i>敲降及过表达分析表明,Hsp70是低氧胁迫下LYCF细胞维持氧化还原稳态及抗氧化应激所必需的;Hsp70可通过维持线粒体膜电位... | zh-cn |
pair_34636195 | YAP/TAZ are wild over-activated in head and neck squamous cell carcinoma (HNSCC) with high potential as a direct therapy target for HNSCC treatments. However, the efforts on the directly targeting-YAP/TAZ therapies over the past decade, have very limited impacts, mainly caused by: 1. There is still none effective and s... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | YAP/ TAZ在头颈肿瘤中普遍异常激活,且对肿瘤生长调控意义重大,故直接靶向YAP/TAZ在头颈部肿瘤治疗中具有极高的潜能。但是随着研究的深入,该策略的局限性也逐步体现,主要表现为两点:1)受限于当前技术水平,暂时还没有发展出安全特异的YAP/TAZ转录辅助激活抑制剂;2)YAP/TAZ调控正常细胞增殖和生存、维持组织成体干细胞的自我更新、参与器官发育、组织大小调节、组织再生等重要生理进程,直接靶向YAP/TAZ可能对这些重要的正常生理活动造成不良影响,存在较大的策略风险。值得注意的是,YAP/TAZ在头颈肿瘤中的异常分子变化比例有限,其异常激活主要源于上游异常分子事件。因此通过研究YAP/TAZ在头颈肿瘤中激活的上游异常分子事件... | zh-cn |
pair_34636196 | The maintenance of bone homeostasis is critical for bone health. It is vulnerable to cause bone loss, even severely osteoporosis when the balance between bone formation and absorption is interrupted. Growing evidence has shown that energy metabolism disorders, such as abnormal glucose metabolism, irregular amino acid m... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 骨稳态的维持对于骨骼健康极为重要,如果骨形成与骨吸收的平衡被打破,容易造成骨量丢失、骨质疏松等多种骨骼疾病。近期越来越多的研究表明,能量代谢失调,例如葡萄糖代谢异常、氨基酸代谢受阻以及脂代谢缺陷等等,都会对骨稳态的平衡造成破坏,从而引起或是加剧导致骨量减少和骨质疏松性骨折等疾病。本文将对能量代谢在成骨细胞以及破骨细胞中的研究进展进行总结分析,深入了解能量代谢,特别是葡萄糖代谢在骨稳态维持中对成骨、破骨细胞分化和功能的关键调控作用,为了解、治疗骨质疏松等骨相关疾病提供指导。. | zh-cn |
pair_34636212 | Parotid gland tumors are usually solitary tumors, and multiple tumors of the parotid gland are extremely rare. We present a highly unusual case of bilateral and simultaneous pleomorphic adenoma and basal cell adenoma of the parotid gland. We review the literature and discuss the clinical manifestations, diagnosis, and ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 腮腺肿瘤常常表现为单发,多发性的腮腺肿瘤发生概率极低。本文报道1例罕见的双侧腮腺肿瘤病例,且病理性质不同,一侧为多形性腺瘤,一侧为基底细胞腺瘤,并结合文献讨论这2种病理类型的腮腺肿瘤的临床表现、诊断及治疗。. | zh-cn |
pair_34636492 | Spinal cord injury (SCI) is one of the serious central nervous system injuries and the incidence of SCI continues to increase. Previous studies have indicated that electroacupuncture (EA) is beneficial for promoting recovery after SCI. In the present study, we attempted to evaluate how EA can promote the neural repair ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 脊髓损伤是一种严重的中枢系统损伤之一,它的发病率一直在升高。既往的研究报道了电针能促进脊髓损伤后的修复。在本研究中,我们试图通过观察Notch信号通路的变化,阐述电针(EA)促进脊髓损伤(SCI)模型大鼠恢复的机制。本实验将大鼠随机分为4组,每组的干预时间分别为1、7、14、28天,每组大鼠随机分为五个亚组,包括:空白对照组(B)、空白电针组(BE)、假手术组(S)、模型对照组(M)、电针组(EA) 。电针组和空白电针组在大椎(GV14)和命门(GV4)穴上进行EA治疗20分钟。每批干预结束后,采用(BBB)评分评估神经功能,我们发现EA组的BBB评分升高,采用苏木精-伊红(HE)染色技术观察各组大鼠受损脊髓局部病理改变,结果显示,... | zh-cn |
pair_34636498 | COVID-19 (coronavirus) has spread all over the world with a high infection rate. Currently, there are no targeted therapeutic drugs for COVID-19 as well as for stress induced by COVID-19. The unpredictable events of COVID-19 can trigger feelings of fear, worry, or unease in people, leading to stress-related disorders s... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 摘要:新冠状病毒(COVID-19)以较高传染率在世界范围内广泛传播。目前,COVID-19的靶向治疗药物仍在研究中。因此,人们对于COVID-19引起的不可预知事件,具有明显的恐惧、担忧或不安感,导致机体产生压力相关的障碍疾病风险增加,如抑郁和焦虑。据报道,在此次COVID-19的流行中,COVID-19患者、医务人员和普通人群,都承受着生理和心理上的双重压力,已经导致许多人患上抑郁症或焦虑症。中医药治疗抑郁症具有相对的安全性和有效性,在COVID-19引起的应激障碍中可能发挥重要作用。因此,本文从PubMed数据库和中国知识网数据库中收集整理了包括气功、针灸、五行音乐、五行情志、中药等在内的常用中医治疗,并阐述其治疗抑郁症的潜在... | zh-cn |
pair_34638183 | As we know, benign paroxysmal positional vertigo is a peripheral vestibular disorder,while vestibular migraine is a central vestibular disease. Although they are two different independent diseases, patients often choose to consult otolaryngology and neurology. The clinical manifestations of some patients with these two... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 良性阵发性位置性眩晕是外周性前庭疾病,前庭性偏头痛是中枢性前庭疾病,虽然二者是不同的独立疾病,但常选择耳鼻咽喉科和神经科两个专科就诊。这两种疾病的部分患者临床表现相似,诊断易混淆,但治疗手段完全不同,治疗方法不正确必然影响疗效和预后。前庭性偏头痛的特点是临床表现和体征具有多样性,部分患者的偏头痛症状与前庭症状不同步,约30%表现为孤立性发作性眩晕/头晕和眼震,极易与良性阵发性位置性眩晕混淆而需鉴别。在前庭疾病国际分类的框架下,依据Barany协会新颁布的眼震检查与分类,依据这两种疾病新的诊断标准进行甄别,可弥补由于学科专业化导致的对二者认识的片面性,提高对包括这两种疾病在内的前庭疾病诊疗水平,以期减少误诊误治。. | zh-cn |
pair_34638184 | Ankle sprains are a common cause of morbidity in the general and athletic population. The majority of sprains involve the lateral aspect of the ankle, affecting the anterior talofibular ligament. However, the extent and categories of injury will depend upon the mechanism of injury. The ankle injury caused by ankle spra... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 踝关节扭伤是普通人群和运动员人群发病的常见原因。大多数扭伤涉及踝关节外侧,影响距腓前韧带。然而,损伤类型和程度将取决于损伤机制。骨性结构和韧带特点是导致踝部扭伤好发的主要原因。踝部扭伤导致的踝关节损伤不止是外侧副韧带损伤,还容易引起距骨骨软骨损伤、前踝撞击症、后踝撞击症等。踝部扭伤除了踝关节受累外,常常导致距下关节和跗横关节损伤,甚至应力性骨折、特殊部位骨折或肌腱软组织伤病,也常常出现多种损伤并存,临床工作中务必高度重视。. | zh-cn |
pair_34638185 | Chronic ankle instability is a chronic sports injury disease characterized by recurrent sprains, feeling of instability, pain, swelling and other symptoms after an initial sprain. Research on the pathological mechanism of chronic ankle instability still cannot explain the diversity of symptoms. In the past, the surgica... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 慢性踝关节不稳是踝关节初次内翻扭伤后出现的以反复扭伤、感觉不稳、疼痛、肿胀等症状为特点的慢性运动损伤性疾病。对于慢性踝关节不稳的病理机制研究仍然无法解释疾病表现的多样性。慢性踝关节不稳的手术指征既往仅强调机械性关节松弛,但外踝扭伤后出现慢性症状前来就诊的患者,多数可能并没有典型的机械性不稳的主诉,更多的患者是以迁延不愈的疼痛或功能性不稳为主诉的。手术治疗对功能性不稳症状也有一定效果,但功能性不稳的手术指征主要依据主观症状,目前缺乏客观指标,仍有争议。需要进一步深入进行慢性踝关节不稳的机制研究,从而指导诊疗策略的制定。. | zh-cn |
pair_34638196 | This retrospective analysis was conducted on clinical obtained DCE-MR images of 198 patients, age from 21 to 79 years(45.5±13.7). The CBAM-ResNet model was developed to perform the classification automatically at the image-level based on deep learning method using the pathological examination as the reference standard,... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 本研究回顾性分析了198例女性患者的乳腺动态增强磁共振成像(DCE-MRI)图像序列,年龄21~79(45.5±13.7)岁。以病理检查为金标准,采用深度学习方法建立CBAM-ResNet自动分类模型,统计图像级别的分类结果,同时结合集成学习思想得到患者个体的分类结果。基于残差网络的CBAM-ResNet分类模型在单张图像层面对乳腺肿瘤的分类准确率达到82.69%,灵敏度为85.67%。采用投票机制后,在患者层面的分类准确率为88.24%,灵敏度为87.50%。试验结果表明该分类算法具有较高的诊断准确率。. | zh-cn |
pair_34638197 | Portal hypertension is an important predictor of the poor prognosis of patients with cirrhosis and hepatocellular carcinoma. The clinical research of portal hypertension should emphasize the cooperation of multidisciplinary team. At present, the quality and quantity of clinical research on portal hypertension in China ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 门静脉高压是导致肝硬化和肝癌患者不良预后的重要因素,其临床研究应强调多学科协同开展。当前,我国门静脉高压临床研究的质量和数量均有待提高。本文建议积极开展'创新技术应用驱动、多学科协作驱动、患者管理优化驱动'的临床研究,立足并服务于我国'门静脉高压共同体'建设。. | zh-cn |
pair_34638198 | Portal hypertension treatment has always been regarded as complex and diverse. With the innovation of concepts and technologies, its treatment model has been transformed from a single-disciplinary diagnosis and treatment model to a multidisciplinary collaborative diagnosis and treatment model. In the multidisciplinary ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 门静脉高压症的治疗一直被认为是复杂、多样的,随着理念与技术的革新,其治疗模式已经从单一学科诊疗模式过渡到多学科协作诊疗模式。在多学科诊疗模式下,门静脉高压症外科治疗并不是即将消失的治疗方式,而是多学科诊疗模式下不可或缺的治疗手段之一,并且将扮演越来越重要的角色。外科医生应该在新的理念影响下,发展个体化、规范化、微创化的治疗方法,把握门静脉高压症的手术适应证,掌握针对不同人群的个体化手术方式,最大程度优化外科治疗门静脉高压症的方法。因此,重新审视外科治疗在门静脉高压症诊疗中的作用是非常有必要的。. | zh-cn |
pair_34638199 | Due to its insidious nature, chronic liver disease usually only appears after a decompensating event, and delays in diagnosis lead to a high mortality. Non-invasive examination can help diagnose and intervene early stage liver fibrosis in patients with chronic liver disease. In a hospital population, this test has been... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 慢性肝病由于其发病的隐匿性,经常在出现失代偿事件后才就诊从而导致其死亡率居高不下。肝纤维化无创检查可以帮助慢性肝病患者早期诊断及干预。这些检查在医院人群中得到了广泛验证,但它们在社区人群中的价值尚不清楚。近年来,国外已有许多针对社区人群进行无创检查的研究,这些无创检查工具均能在社区人群中筛查出慢性肝病及肝硬化患者。进一步研究发现,针对具有肝病危险因素(大量饮酒、2型糖尿病、肥胖)的社区人群进行筛查,能更加高效地筛出社区人群中的慢性肝病患者。总之,相较于传统的依赖于异常肝功能化验的社区筛查,无创检查可以在社区人群中发现到大量之前未被发现的肝病患者。针对无创检查在社区人群中筛查慢性肝病展开讨论,以便于在我国寻找一条开创性的社区无创肝病筛... | zh-cn |
pair_34638214 | Gastric varices are one of the serious complications of liver cirrhotic portal hypertension. Balloon-occluded retrograde transvenous obliteration (BRTO), as an interventional treatment method, can effectively prevent and control gastroesophagel variceal bleeding. Simultaneously, it has an obvious effect in the treatmen... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 胃静脉曲张是肝硬化门脉高压症的严重并发症之一,球囊阻断逆行经静脉闭塞术(BRTO)作为一种介入治疗手段,能有效预防和控制胃静脉曲张出血,同时在治疗肝性脑病和改善肝功能上有明显的效果。就近年来国内外对BRTO的临床应用、研究进展作一综述,期望为临床治疗提供参考。. | zh-cn |
pair_34638215 | Chronic liver disease causes bleeding and coagulation system abnormalities through a variety of mechanisms. Thrombocytopenia is a common complication of chronic liver disease. Patients with chronic liver disease, especially liver cirrhosis, often face more invasive examinations or surgeries, which brings great challeng... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 慢性肝病通过多种机制引发出血和凝血系统异常,血小板减少是慢性肝病常见并发症,而慢性肝病,尤其是肝硬化患者往往面临较多的侵入性检查或手术,这给临床诊疗带来了较大的挑战。传统血小板输注是主要的临床干预措施,随着促血小板生成素受体激动剂的获批,慢性肝病相关血小板减少症的现行管理标准可能面临改变。综述慢性肝病相关血小板减少症目前主要非药物和药物干预措施,并基于这些干预措施的疗效和局限性,提出相应的临床管理改进策略。. | zh-cn |
pair_34638216 | Chemokine CXC ligand 12 (CXCL12)-chemokine receptor 4 (CXCR4) signal axis is involved in the regulation of liver injury repair and the occurrence and development of liver fibrosis. In case of acute and chronic liver injury, the expression of CXCL12 is up-regulated to collect CXCR4-positive immune cells to migrate to th... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 趋化因子CXC配体12(CXCL12)-趋化因子CXC受体4(CXCR4)信号轴参与调控肝损伤修复和肝纤维化的发生与发展。急慢性肝损伤时,CXCL12表达上调,募集CXCR4阳性免疫细胞向肝脏迁移。CXCL12-CXCR4通路通过促进肝星状细胞的活化和增殖参与肝纤维化的发生。CXCR4小分子抑制剂的出现使该受体成为抗纤维化治疗的一个有吸引力的靶点。目前,CXCR4已经被尝试用于多种脏器纤维化包括肺纤维化、慢性胰腺炎等抗纤维化治疗的靶点。但是部分研究显示单纯阻断CXCL12/CXCR4轴并不能改善肝纤维化,甚至加重肝损伤。近年来随着CXCR12另一受体CXCR7的发现和认识,CXCR4促纤维化通路和CXCR7促再生通路在肝再生和肝纤维... | zh-cn |
pair_34638217 | Adenosine, as an endogenous purine nucleoside, is widely distributed in various tissues and organs of the body. It binds to adenosine receptors to regulate a variety of important biological processes. Adenosine 2A receptors have a close relationship with the occurrence and development of various clinical diseases. This... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 腺苷,作为一种内源性嘌呤核苷,广泛分布于全身各组织器官,与腺苷受体结合,调节多种重要的生物过程,其中腺苷2A受体与多种临床疾病的发生、发展都有着密切的关系。现主要综述腺苷2A受体在非酒精性脂肪性肝病、急性免疫性肝炎、肝脏缺血-再灌注损伤和肝纤维化等多种肝脏损伤中的作用研究进展,以期为上述疾病的防治研究提供新的策略。. | zh-cn |
pair_34638218 | Exosome is a kind of biological nano-vesicle with a diameter of about 30-100 nm and is synthesized, secreted, and released in almost all types of body cells. Recent studies have found that exosomes contain a variety of functional proteins, including mRNA and microRNAs (miRNAs) and so on, which play an important role in... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 外泌体是一种生物纳米小囊泡、直径约30~100 nm,机体中几乎所有类型的细胞均可以合成、分泌、释放。最新研究发现,外泌体中包含多种功能蛋白质、mRNA和microRNAs (miRNAs)等,在细胞间进行物质传递和信息交流过程中起着非常重要的作用。而肿瘤细胞分泌的相关外泌体miRNA,对肿瘤的发生、发展、侵袭转移等生物学过程均发挥了重要的调控作用。因此,研究肿瘤相关外泌体miRNA,将有助于从肿瘤基因调控视角去研究肿瘤进展的作用机制,并挖掘新的肿瘤标志物,有助于肿瘤早期诊断、治疗及疾病监测和预后评估。. | zh-cn |
pair_34643070 | The pygmy marmoset, the smallest of the anthropoid primates, has a broad distribution in Western Amazonia. Recent studies using molecular and morphological data have identified two distinct species separated by the Napo and Solimões-Amazonas rivers. However, reconciling this new biological evidence with current taxonom... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 作为全球最小的类人猿, 倭狨在西亚马逊分布极广。近期整合分类学研究表明,目前认为的“倭狨”实际代表了两个独立的物种,二者分布以纳波河-索利蒙伊斯河为界,而其目前的两个亚种应提升为有效种。然而,由于倭狨指名亚种的模式产地相较河流的具体位置不明,因此难以确定两个已有学名与演化支系间的具体对应关系。在此,该研究首次提供了倭狨指名亚种模式标本的DNA分子数据,同时提供了模式产地界河两侧个体的线粒体基因组数据。基于上述数据,该研究确定了河流北部的狨猴种群对应真正的倭狨 <i>Cebuella pygmae</i>,而河流南部种群则对应新提升有效性的东部倭狨 <i>C. niveiventris</i>。结合已有的线粒体细胞色素b数据,研究重新... | zh-cn |
pair_34643071 | Salamanders are unique among tetrapods in their ability to regenerate their limbs throughout life. Like other poikilothermic amphibians, salamanders also show a remarkable capacity to survive long periods of starvation. Whether the physiological reserves necessary for tissue regeneration are preserved or sacrificed in ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 两栖类蝾螈具有独特的肢体再生能力。与其他两栖类动物类似,蝾螈也拥有极强的饥饿耐受能力。在饥饿的蝾螈体内,肢体再生是否能正常进行,禁食后蝾螈如何利用物质储存来促进再生还不得而知。我们对西班牙肋突螈 ( <i>Pleurodeles waltl</i>) 进行长期禁食处理,使其处于极端饥饿的状态,然后检测其断肢再生能力。经过长达近两年的禁食,动物形态与生理状态都发生了显著的变化,但仍能保持正常机体功能。禁食动物各种组织内的自噬水平都有所上升,肠道微生物的重塑也与细胞自噬相关。对禁食的动物进行截肢手术后,发生了大量细胞增殖并生成了再生芽基,但是再生的速率比正常喂食组有所减弱。在禁食动物中抑制自噬,能够减缓细胞增殖与再生芽基生成,而自噬抑制... | zh-cn |
pair_34643278 | There are a variety of educational interventions for families who have a relative with a mental health disorder. However, for those with one or more emotion dysregulation disorders, there are limited options. This article reports on the results of a pilot project using a quasi-experimental design with a sample of 270 (... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 对于亲属患有精神健康障碍的家庭有各种教育干预措施。然而,对于那些有一种或多种情绪失调障碍的人来说,选择则是有限的。本文报告了一个试点项目的研究结果,使用的是一项针对需要应对和管理亲人情绪调节障碍的准实验设计(干预=217,对照=53)来评估GOER家庭课程的干预效果(即get Off the Emotional Roller Coaster技能建设家庭教育课程)。他们的亲人的精神障碍疾病经常被误诊或与物质滥用是同时发生的。这种干预措施可以有效地减轻护理人员的负担 [F (1,120 )=12.25, p=.001],同时改善态度、知识和技能 [F (1,170)=6.16, p=.014]。面临这些精神疾病带来的挑战和责任的家庭,特... | zh-cn |
pair_34643278 | There are a variety of educational interventions for families who have a relative with a mental health disorder. However, for those with one or more emotion dysregulation disorders, there are limited options. This article reports on the results of a pilot project using a quasi-experimental design with a sample of 270 (... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Existen varias intervenciones educativas para las familias que tienen un familiar con un trastorno de salud mental. Sin embargo, para aquellos que padecen uno o más trastornos de desregulación emocional, existen pocas opciones. En este artículo se informan los resultados de un proyecto piloto usando un diseño cuasiexpe... | es |
pair_34645116 | The Christian missionaries preached through medicine by combining religious preaching with secularisation and social adaptiveness of medicine in the 19th century. They attempted to avoid the negative influence of culture differences between the West and China. Desjacques Marin, one of the missionaries in China, was ent... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 近代传教士借医传道,将传道的宗教性与医疗的世俗性和社会适应性结合起来,试图避开中西文化差异造成的不利影响。1864年,传教士杜若兰受法国领事爱棠的委托创办医院,名为General Hospital(综合医院)。1877年迁至苏州河北岸,取名公济医院。1940年,公济医院被日军指定为病囚医院。1945年,由国民政府作为敌产接管,成为公立医院,对国人开放。1953年,公济医院更名为“上海市立第一人民医院”。研究教会医院的历史变迁对于中国医学史的研究和中西医学交流具有重要意义。. | zh-cn |
pair_34645117 | Palliative and Hospice Care initially developed in Great Britain. It was founded by Cicely Saunders for the humane care of terminally ill cancer patients and her institution was established as the first modern hospice in England. The concept developed gradually into a systematic medical program for terminal ill patient... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 安宁疗护起源于英国,最初由桑德斯出于对癌末患者的人道关怀而创办安宁疗护机构,并逐渐发展成为一种独特的临终照护体系,在全世界得到推广。中国台湾地区的安宁疗护发展,呈现了政府与社会共同参与的特点。当下中国有着对安宁疗护的迫切需求,这些过往经验可以提供一些借鉴。. | zh-cn |
pair_34645118 | Animal drugs and their paintings were recorded in both <i>Ben Cao Tu Jing</i>(Illustrated Classic of Materia Medica) and Sman Thang of Tibetan medicine. By analyzing the species,techniques of expression, and facticity in the book and the paintings, different characteristics of animal drugs and their paintings were mani... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 《本草图经》和藏医80幅曼唐中均有对动物类药物的记载,并绘制了相应的药图。通过比较可以看出,两者在所收动物药范围、表现方法和真实度3个方面各有异同,分具特色。由此展现出不同民族在图像表达方面的差异,体现出不同文化异彩纷呈的面貌。. | zh-cn |
pair_34645120 | The Jiangpu Ding family was a Gentry Family with many scholars in Nanjing, running through the Ming and the Qing Dynasties. Successful in both medicine and the imperial examination, talents in various fields emerged in large numbers over more than ten generations. Their practice of medicine began with Ding Zhongbao fro... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 江浦丁氏是南京地区从明初开始传承延续,贯穿明清两朝的士人家族,科第繁荣,医风尤著,历经十余代,各领域人才辈出。丁氏行医自初代丁仲宝始,第二代丁毅由医入仕,业医之风初现,经数代积累,至丁凤医名大盛。但其整个世系专职业医者也仅丁毅、丁凤二人,本质上仍是一个传统士人家族。其特别之处在于,明中期丁凤之后,虽无专职医者,但后代医风未有衰减,家族仍将医术作为家族子弟必修技能。其家亦有《医方集宜》《痘科玉函集》《行医八事图》等医著传世。. | zh-cn |
pair_34645122 | Professor Ying-ao YU came from a family with medical background and studied under the guidance of Bo-wei QIN. He graduated from Shanghai Second Medical College. He also was a graduate of the first session of the Integrated Medicine in China. After that, he was assigned to the editorial office of the Academy of Chinese ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 余瀛鳌教授谦逊恭谨,出身世医家庭,师承秦伯未,毕业于上海第二医学院,参加首届全国西医离职学中医研究班,成绩优异,毕业后被分配在中医研究院编审室,从事中医临床文献研究工作,临床擅长中西医结合,曾与国医大师路志正教授赴内蒙古包钢职工医院支边开展中医医疗与培训,致力于中医临床文献和通治方研究60余年。在临床和文献研究的工作过程中,逐渐形成了“辨病辨证—通治法—通治方—临证化裁”的诊疗模式,成为研究通治方学者中的一员,著述丰厚,创立新说,在中医临床和临床文献研究方面做出了杰出的贡献。在跟师的过程中,系统访谈了余师在中医临床、中医临床文献学与中医师承的经历,整理成篇,以飨读者。. | zh-cn |
pair_34645123 | With the development of Huizhou studies and its medical history becoming a new growth area of Chinese historiography, the medical social history in Huizhou has been a focus in academic fields, and a series of research achievements have been reported. However, as far as the current research is concerned, some problems a... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 在徽学研究向纵深处开展和疾病医疗史成为中国史学新增长点的共同作用下,徽州医疗社会史日渐受到学界关注,取得了一系列研究成果。但就目前研究而言,仍存在下述问题与不足:对民间个体的生命缺乏关注;新安医学“内史”和“外史”的整合未受到足够关注;徽州与其他地域医疗史的比较研究过于薄弱。鉴于这些问题,未来的研究应从下述方面着手:徽州医疗社会史这一领域本身成为未来一个重要研究方向;呈现“人”的徽州日常医疗世界;更多触及新安医学知识这一内核;从比较中认识医学与地域的关系。. | zh-cn |
pair_34645144 | Regarding the relationship between malocclusions and temporomandibular disorders (TMD), from the leading cause to one of the local biological factors, the change in the understanding of the academic community since the 1980s has affected the clinical diagnosis, treatment behavior, and the direction of scientific resear... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 关于咬合异常与颞下颌关节紊乱病(temporomandibular disorders, TMD)的关系,从主导病因到仅为局部生物学因素之一,自1980年代以来学术界的认识转变影响到临床诊治行为和研究方向。目前认为TMD致病因素为多因素,咬合因素与TMD的发生关联性较弱,但是有一些共性的咬合异常比如非工作侧(牙合)干扰、最大牙尖交错位和后退接触位之间过度滑动、最大牙尖交错位不稳定等可能是促进TMD发生的危险因素。行为、生物学、环境、社会认知、精神心理等因素的综合作用可以促进TMD症状的发生。在教学和临床工作中不能忽视医源性咬合创伤对促进TMD发生的风险,应重视患者的社会心理环境对疾病的影响,推荐综合治疗方法。. | zh-cn |
pair_34645145 | The complexity of burn metabolism and limitations of its cognition are the core factors leading to dissatisfactory efficacy of nutritional therapy in severe burn patients. Precise understanding of burn metabolic rules is a prerequisite for improving the pertinence and effectiveness of nutritional therapy. The previous ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 烧伤代谢的复杂性和对其认识的局限性是导致重症烧伤患者营养疗效不甚理想的核心因素,对烧伤代谢规律的准确把握是提升营养针对性和有效性的前提。以往基于能量消耗的烧伤代谢分期对物质代谢关注不够,因而难以全面描述烧伤代谢的整体变化规律和阶段性特征。本文通过对烧伤代谢组学、生理组学和临床检测数据的有效整合,并结合烧伤临床分期的病理生理特征,将重症烧伤患者的代谢过程分为4期,并针对其代谢特征提出了相应的营养治疗策略与措施,以期为进一步提升烧伤营养疗效提供依据。. | zh-cn |
pair_34645155 | Severe burns can lead to persistent hypermetabolism. Studies have shown that early enteral nutrition therapy is related to improving the prognosis of severe burn patients, reducing the mortality rate, and reducing gastrointestinal complications and infectious complications. This article introduces the nutritional benef... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 严重烧伤会导致持续性的代谢亢进,研究显示尽早开展肠内营养治疗与改善严重烧伤患者预后、降低病死率、减少胃肠道并发症和感染性并发症等存在相关性。本文介绍了严重烧伤患者早期肠内营养治疗的营养益处及非营养益处(维持肠黏膜功能和结构的完整性及促进创面愈合)、营养治疗介入的时机和途径、能量评估方法及营养监测等,旨在为早期肠内营养治疗临床决策提供参考。. | zh-cn |
pair_34645156 | The vagus nerve plays an important role in regulating the homeostasis of inflammation. Inflammation signals in the body are passed to the vagus nerve efferent fibers via nerve reflexes, and the signals generated by efferent fibers will play an anti-inflammatory role in various inflammatory diseases through immune cells... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 迷走神经在调节全身的炎症稳态中起着重要作用。体内的炎症信号经由神经反射传递给迷走神经传出纤维,后者产生的信号通过巨噬细胞、表达胆碱乙酰转移酶的T细胞等免疫细胞在各种炎症疾病中发挥抑炎作用。但是炎症的解决不仅仅是促炎性细胞因子与抗炎细胞因子的相互角力,更是一个生物合成的主动过程,其中包括各种促分解介质的合成以及它们的生理效用过程。此外,胆碱能炎症反射在炎症消退过程中同样发挥着重要作用。本综述回顾并总结了胆碱能炎症反射及其在炎症消退过程中的重要作用。. | zh-cn |
pair_34645157 | At present, a variety of biocompatible materials have been applied in treating diabetic wounds, and some biocompatible materials have played an important role. Although biocompatible materials have advantages such as decreasing exposure and tension of wounds, and providing microenvironment to stimulate cell proliferati... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 目前多种生物相容性材料已经被应用于糖尿病创面的治疗中,且部分生物相容性材料发挥了重要作用。虽然生物相容性材料具有减少创面暴露、创面张力,提供促进细胞增殖、迁移的微环境等优点,但是仍然存在效果不稳定、机制不明确的不足。因此,本文综述了近期将生物相容性材料用于治疗糖尿病创面的进展,并讨论了生物相容性材料领域可能的发展方向。. | zh-cn |
pair_34645158 | Children are at a critical period of growth and development, their body function and quality of life will be greatly reduced by the direct or indirect impact of burns. Therefore, rehabilitation therapy after burns is very important for the treatment of burned children. Resistance training is one of the rehabilitation e... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 处于生长发育关键时期的儿童,受烧伤的直接或间接影响,其机体功能和生活质量都会大大降低。因此烧伤后的康复运动对烧伤患儿的救治至关重要。抗阻训练是患者进行康复运动的方式之一。本文综述了抗阻训练对烧伤患儿伤后康复的影响,总结了目前相关研究的优势和不足,为以后的研究提供了参考和思路,以期提高烧伤患儿的总体预后。. | zh-cn |
pair_34645159 | As the largest organ in mammals, skin is the first protective barrier against external stimuli. Sweat glands are one of the important cutaneous appendages and play an important role in maintaining electrolyte balance and regulating body temperature. Patients with extensive deep burns usually suffer from damage to deep ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 皮肤作为哺乳动物最大器官,是抵御外界刺激的第1道防护屏障。汗腺是皮肤重要附属器之一,在维持电解质平衡和调节体温方面起着重要作用。大面积深度烧伤患者通常损伤会达真皮深层甚至皮肤全层,损伤汗腺修复困难,甚至无法再生,患者排汗和体温调节功能受到严重影响,生活质量降低。如何实现汗腺的功能化成为损伤皮肤再生医学的重要研究内容之一。本文对干细胞、组织工程等汗腺再生修复的转化应用技术进行阐述,拟为汗腺再生研究提供理论参考。. | zh-cn |
pair_34645160 | Colorectal cancer is one of the malignant tumors with the highest morbidity and mortality in China. With the research of precision medicine concept and tumor-related molecular markers, appropriate detection and application of colorectal cancer-related molecular markers has become an important part of current clinical p... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 结直肠癌是目前我国发病率及死亡率最高的恶性肿瘤之一。随着精准医疗理念及对肿瘤相关分子标志物研究的逐年深入,合理的检测及应用结直肠癌相关分子标志物已经成为目前临床实践的重要部分。为了提高临床医师对结直肠癌分子标志物的了解及应用,中国临床肿瘤学会(CSCO)结直肠癌专家委员会组织相关领域专家,根据近年的国内外临床研究及实际诊疗经验,经专家组反复修改讨论,撰写了结直肠癌分子标志物临床检测的专家共识,旨在为临床医师提供参考及指导,为结直肠癌患者提供更加精准、有效的治疗。. | zh-cn |
pair_34645161 | Gastrointestinal cancer peritoneal metastasis(GICPM) is one of the biggest challenges of clinical treatment. The ultimate solution to the problem requires the clinicians to accurately understand cytologic and molecular pathological mechanisms behind GICPM, and apply such knowledge in the clinical decision-making proces... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 胃肠道癌腹膜转移是目前临床治疗的最大难题,解决该难题的根本之道在于临床医生准确把握胃肠道癌腹膜转移的核心细胞病理学机制,基本掌握分子病理学机制,并融会贯通地运用到每一例患者诊治的临床决策过程中,做到'防''治'并举,积极预防、主动治疗。与临床治疗决策密切相关的胃肠道癌腹膜转移的核心细胞病理学机制有4点:(1)腹腔游离癌细胞或微癌灶定植于腹膜,对腹膜间皮细胞造成不可逆病理性损害;(2)定植的癌细胞进一步侵袭腹膜特定结构乳斑,启动加速侵袭性生长过程;(3)腹膜间质纤维化过程加重腹膜的结构性破坏;(4)癌细胞与乳斑中免疫细胞的相互作用,形成促进腹膜转移癌生长的容受性免疫微环境。这4条核心细胞病理学机制互为因果,相互促进,构成腹膜转移发展的... | zh-cn |
pair_34645162 | Peritoneal metastasis is the most common distant metastasis of gastric cancer. As an end-stage event of gastric cancer, patients with peritoneal metastasis often have lost the chance of radical resection, and even after palliative surgical resection, the long-term outcomes are still not satisfactory. In recent years, w... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 腹膜种植转移是胃癌常见远处转移方式。作为胃癌终末期事件,发生腹膜转移的胃癌患者往往已经失去手术根治机会,即使行外科手术切除,远期预后仍不理想。近年来,随着腹腔镜技术、腹腔化疗、腹腔热灌注化疗等临床诊疗技术的应用与推广,在多学科诊疗模式及围手术期综合治疗策略的支持下,一部分已经发生腹膜转移的胃癌患者获得了根治性手术切除机会,提高了生活质量,延长了生存时间。考虑到近年胃癌腹膜转移治疗领域的进展,本文拟结合目前临床证据,对胃癌腹膜种植转移的临床诊疗过程中的关键问题,包括腹膜转移的影像学诊断、腹腔镜检查、腹膜转移的评估以及综合诊疗方案进行讨论。. | zh-cn |
pair_34645163 | Peritoneum is a common metastatic site of colorectal cancer and has worse prognosis compared with other metastatic sites. Peritoneal metastasis was previously considered as a terminal state of the disease, and palliative treatment with systemic chemotherapy was the main treatment method. With the gradual acceptance of ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 腹膜是结直肠癌常见的转移部位,与其他转移部位相比预后较差。早期的观点认为,腹膜转移是疾病的终末状态,全身化疗为主的姑息性治疗是其主要治疗手段。随着肿瘤细胞减灭术(CRS)+腹腔热灌注化疗(HIPEC)的治疗模式逐渐得到外科医生的认可,以及靶向治疗和免疫药物的应用,结直肠癌腹膜转移患者的预后得到了很大改善。然而,结直肠癌腹膜转移的诊治仍面临很多挑战和争议。本文从对结直肠癌腹膜转移的认识演变出发,讨论了腹膜转移可能的机制,包括'寡转移'学说和'种子-土壤'学说;进一步探讨了结直肠癌腹膜转移的诊治策略及面临的挑战,包括影像学检查的局限性、腹腔镜探查的争议、腹膜转移负荷评估困难、术后复发监测和疗效评估手段有限以及中国不同地区间诊治水平差异较... | zh-cn |
pair_34645164 | Peritoneal metastasis of gastrointestinal cancer is an independent factor that seriously affects the prognosis of patients. The 'seed-soil' theory is considered to be the main theory to explain peritoneal metastasis. Because of the small size of peritoneal metastatic nodules at the initial stage, early diagnosis is par... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 腹膜转移是严重影响胃肠道癌患者预后的独立不良因素,'种子-土壤'学说被认为是解释腹膜转移的主要理论。由于腹膜转移结节初发时体积小,早期诊断尤为困难,因此,腹膜转移的风险评估就显得尤为重要。目前诊断方法已由临床病理因素逐渐向细胞学、乃至分子层面纵深发展,而包括影像组学在内的多组学整合评估,也进一步丰富了腹膜转移的精准诊断。腹膜转移可导致癌性腹水、肠梗阻及恶液质等相关并发症,是胃肠道癌治疗的难点。以系统化疗为基础、手术和腹腔热灌注化疗(HIPEC)等多种方法相结合,是胃肠道癌腹膜转移的有效治疗手段。如何富集潜在获益的腹膜转移患者,如何判定转化手术的时机,如何进一步优化现有治疗方案,特别是转化手术后的患者如何制定治疗方案等,仍需通过完善研... | zh-cn |
pair_34645165 | Peritoneal carcinomatosis (PC) is one of the difficult problems in the treatment of colorectal cancer (CRC). Based on several retrospective analyses of large samples and prospective randomized controlled studies (RCTs), NCCN and PSOGI recommend cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 腹膜转移是结直肠癌治疗领域的热点和难点,NCCN指南和PSOGI推荐肿瘤细胞减灭术(CRS)加腹腔热灌注化疗(HIPEC)治疗轻中度结直肠癌腹膜转移。在CRS+HIPEC治疗结直肠癌腹膜转移领域,腹膜转移高风险患者行二次探查+HIPEC是否有生存获益,以及HIPEC在该整合治疗体系中的价值,是两个争议已久的重要问题。针对上述问题,法国学者开展了两项随机对照研究:PROPHYLOCHIP研究和PRODIGE 7研究。(1)PROPHYLOCHIP研究发现,腹膜转移高风险患者初次手术后,密切观察组与二次探查+HIPEC组的DFS、OS比较差异无统计学意义,认为若初次手术理想、肿瘤细胞减灭完全,则无必要行二次探查+HIPEC;(2)PRO... | zh-cn |
pair_34645166 | Colorectal surgery has been developed rapidly in China because of the advance of minimally invasive surgical techniques, perioperative comprehensive treatment strategies and clinical research in recent years. Comparing the current diagnosis and treatment of colorectal cancer between China and western industrialized cou... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 得益于近年来微创外科技术的发展、围手术期综合治疗策略和临床研究的进步,我国的结直肠外科也得到了快速发展。但对比我国与欧美发达国家的结直肠癌诊疗现状可以发现,西方发达国家的结直肠外科的专科化建设和规范化诊疗已经非常成熟,结直肠癌的多学科诊疗模式业已规范化运行。尽管我国东部沿海地区的高水平结直肠癌诊疗中心与西方国家相比已几乎无差距,但由于我国幅员辽阔且地区发展不平衡,结直肠外科的标准化手术以及规范化治疗理念仍有待普及。我国结直肠外科领域要寻求新的发展和突破,就要进一步开展更高质量的临床研究。笔者结合已参与和开展的国际国内临床研究经验,认为应该从以下两点对临床研究进行质量控制:(1)研究的结构化培训和质量控制;(2)数据库的建立和管理。总... | zh-cn |
pair_34645173 | Surgery is recognized as the core treatment for colorectal liver metastasis (CRLM), while its recurrence rate remains relatively high, even for resectable CRLM. This hints that the efficacy of treatment involves not only technological factors of surgery, but also biological behavior of tumor. For resectable CRLM, neoad... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 外科手术是结直肠癌肝转移(CRLM)治疗的核心手段,但即使是初始可切除的CRLM,仍存在较高的术后复发率。究其原因,除了外科因素,肿瘤生物学行为层面的'可切除'更能预测治疗的有效性。对于初始可切除CRLM,新辅助治疗有利于消灭微转移、降低术后复发率、筛选肿瘤生物学行为、改善预后。但是,哪一类CRLM患者更适合接受新辅助治疗,其方案该如何选择等问题仍存在较多争议。本文将从初始可切除CRLM的分层管理、新辅助治疗的策略和方案选择,特别是联合靶向药物的价值等方面,结合最新指南和研究进展进行综述。. | zh-cn |
pair_34645174 | The COVID-19 pandemic shows the defects of current public health law system and the necessity of the amendment to Law on Prevention and Treatment of Infectious Diseases. The institutional design of the prevention and control of emerging communicable disease shall be modified and Principle of Preventive Legislation shal... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 新型冠状病毒肺炎疫情显示出当前公共卫生法治体系的缺陷,应尽快修改完善《传染病防治法》:完善新发传染病防治的制度设计,确立新发传染病监测的风险预防原则,加强流行病学调查的法治保障;坚持疫情防控的多元协同,厘清中央和地方政府的责任,充分发挥专家和公众的作用;改革疫情信息发布制度,解决法律冲突问题,优化信息直报制度和直报系统;遵循疫情防控中的比例原则,保障防疫措施的妥当性、必要性和均衡性。. | zh-cn |
pair_34645175 | Antibody-dependent enhancement (ADE) refers to the process in which some virus-specific antibodies (generally non-neutralizing antibodies) bind to the virus and bind to some cells expressing FcR on the surface through their Fc segment, thereby mediating the endocytosis and replication of the virus and enhancing the inf... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 抗体依赖的增强作用(ADE)是指某些病毒特异性抗体(一般多为非中和抗体)与病毒结合后,通过其Fc段与某些表面表达FcR的细胞结合从而介导病毒内吞和复制,增强病毒感染的过程。本文概述了ADE在呼吸道合胞病毒、登革病毒、流感病毒等几种传染性疾病中的相关研究发现,借鉴ADE在几种病毒传染性疾病中发生的情况,探讨新型冠状病毒肺炎发生ADE的可能性及其作用机制,期望为新型冠状病毒肺炎发病机制、重症治疗和疫苗研发提供一些见解。. | zh-cn |
pair_34645189 | From December 2017 to December 2018, 3 509 subjects who had regular physical examination in Health Management Center, Tianjin Medical University General Hospital were enrolled in our study, including 399 cancer patients, 1 555 chronic disease patients, and 1 555 healthy control, respectively. The mean age was (55.87±11... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 2017年12月至2018年12月,在天津医科大学总医院健康管理中心定期健康体检的3 509名研究对象中,曾罹患肿瘤、罹患慢病和健康对照三组分别有399、1 555、1 555名。年龄为(55.87±11.98)岁,男性占31.38%。慢病组MS患病率(42.44%)高于曾罹患肿瘤组(34.59%)和健康对照组(18.65%)(<i>P</i><0.001)。与健康对照组相比,曾罹患肿瘤组和慢病组MS患病风险<i>OR</i>(95%<i>CI</i>)值分别为2.13(1.61~2.83)和2.85(2.23~3.66);曾罹患乳腺癌和甲状腺癌MS患病风险<i>OR</i>(95%<i>CI</i>)值分别为3.56(2.04~6... | zh-cn |
pair_34645190 | This study collected nasopharyngeal swab specimens from severe respiratory infection cases in First People's Hospital of Yuhang District during 2016-2019. Real-time PCR was used to detect respiratory syncytial virus (RSV). Rate of RSV positive detection were analysised in different age groups and different months. A to... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 收集2016年1月至2019年12月杭州市余杭区第一人民医院的严重急性呼吸道感染病例鼻咽分泌物标本,采用荧光定量PCR方法进行RSV病毒核酸检测;检测后分析不同年龄组、不同月份RSV阳性检出情况。结果显示,共收集并检测973份鼻咽拭子标本中,63份标本RSV核酸检测阳性,阳性检出率为6.47%;核酸检出率男性大于女性,但两者差异无统计学意义(<i>P</i>=0.230);RSV检出率与年龄呈负相关,0~1岁婴幼儿和1~2岁婴幼儿年龄组检出率最高,分别为15.2%和12%;RSV的流行有明显的季节性差异,每年冬季和春季是RSV流行高峰期。. | zh-cn |
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