term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
SLC superfamily of solute carriers
8
43
3.117467
0.001824
Q6NT16,O43772,Q8IXU6,Q70HW3,P41440,Q9H2D1,Q9H2H9,Q6N075
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
7,10,12,49,115,184,84,58
614,10,1131,889,818,2658,764,1048,969,2669,1980,1098,115,192,1786,1471,1686,58,7,713,2053,49,12,1030,528,511,1440,640,781,1342,1038,184,84,1915,1294,608,880,516,812,1215,1084,697,789
0.4225314103597223,4.396604319498196,0.02222921008355008,0.18589586847145548,0.23937792178355133,-1.8368287909913394,0.2923398612170866,0.07733177575208161,0.13188385952514886,-2.0740082524478405,-0.4699677127277454,0.0498499651371408,1.7398321727024608,1.3211587294181275,-0.350125356105606,-0.17512221304650355,-0.2911692129463672,2.436706104734128,4.50404309487471,0.3447912610633156,-0.5003402500028168,2.745005746127423,4.224818104379722,0.10467597056101892,0.5244829444562599,0.5496741112974982,-0.14649000038336524,0.4225314103597223,0.2923398612170866,-0.08967050071108885,0.10467597056101892,1.3645361307346424,2.090348997439926,-0.4097204049195783,-0.06148029559266701,0.4481994586006217,0.2127025180887077,0.5496741112974982,0.2659233011870234,-0.005531837066441173,0.07733177575208161,0.37082842982646413,0.2923398612170866
2,702
Dementia
12
49
3.091191
0.001994
P00403,P17900,P06865,Q9Y487,P61916,Q6Y7W6,Q13510,Q14108,O15118,P07602,P35637,Q9NQZ5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,70,168,78,142,110,111,19,24,57,155,60
790,24,926,363,2144,699,35,443,2383,210,168,57,891,1667,70,499,1717,345,2152,1719,1985,155,898,1780,1569,796,2394,2086,2088,1882,142,1838,1021,111,19,944,805,110,2572,1159,1744,1746,956,2593,1911,60,880,1041,78
0.2659233011870234,3.530739879481159,0.15895673427969537,0.747090864182487,-0.5924746168808616,0.3447912610633156,3.1141580717849924,0.6245521818790327,-0.8136248100970255,1.2333342498208812,1.4075642865122227,2.436706104734128,0.18589586847145548,-0.2911692129463672,2.2572569188414064,0.5496741112974982,-0.32056824010222307,0.7953385242734627,-0.5924746168808616,-0.32056824010222307,-0.4699677127277454,1.4714633126430223,0.18589586847145548,-0.350125356105606,-0.2328390217993925,0.2659233011870234,-0.8136248100970255,-0.5308810490428666,-0.5308810490428666,-0.4097204049195783,1.5554884161976426,-0.37984219227896826,0.10467597056101892,1.7799433878907398,4.111237733873485,0.15895673427969537,0.2659233011870234,1.7998858840313976,-1.1800104648843361,0.02222921008355008,-0.32056824010222307,-0.32056824010222307,0.15895673427969537,-1.2492972789568666,-0.4097204049195783,2.3835119137294205,0.2127025180887077,0.10467597056101892,2.2206204495029636
2,702
Transmembrane transport
28
186
3.09036
0.001999
Q99595,Q9NS69,Q6NT16,O75964,P62258,O43772,Q9BPX6,Q8IXU6,Q8NB49,P45880,P21796,P00403,Q9C0H2,O95831,Q13423,Q70HW3,Q9H2D1,P08183,P53985,Q8WTV0,Q6P4A7,O75844,Q9H2H9,Q15388,P23786,Q9UHG3,P41440,Q9HD20
Processes and pathways
GO Biological process
msigdb_gobp
5,6,7,256,257,10,139,12,146,23,31,35,165,39,177,49,184,189,192,69,75,74,84,86,88,95,115,252
440,1410,1867,614,1708,852,267,729,887,10,1131,460,1661,888,2561,1361,1456,2324,889,74,2575,1136,256,966,818,2658,39,699,35,443,764,968,1462,1048,619,292,560,2189,820,189,969,666,1268,765,2669,1269,1222,1980,1098,477,702,1012,1312,1503,649,823,1772,2257,31,1417,88,621,896,2565,1563,1463,2362,2118,1776,2364,1366,2688,1015,898,413,1780,115,1569,23,767,1370,1421,2394,379,900,368,2042,1277,192,1676,1943,369,347,2334,2335,414,1680,257,628,770,2127,1786,1107,1471,901,1839,1283,594,1284,177,2093,1062,2271,1287,86,1893,1686,1434,1379,1190,1288,7,713,2053,75,49,504,870,12,1794,836,146,948,2235,1030,528,2101,1586,69,1640,2467,2665,1956,955,511,2628,1440,2593,5,436,780,640,139,781,451,1342,2104,165,1038,184,84,1915,1294,607,608,252,470,6,1652,516,721,611,1923,95,1348,812,576,2176,329,1215,921,1043,644,1084,2616,789
0.6245521818790327,-0.14649000038336524,-0.4097204049195783,0.4225314103597223,-0.32056824010222307,0.2127025180887077,1.0072634916981495,0.31862879037972053,0.18589586847145548,4.396604319498196,0.02222921008355008,0.5997077106006617,-0.2911692129463672,0.18589586847145548,-1.1456872992127736,-0.1180065861783075,-0.17512221304650355,-0.7495318851344548,0.18589586847145548,2.2206204495029636,-1.2145462814230732,0.02222921008355008,1.0303037635203478,0.13188385952514886,0.23937792178355133,-1.8368287909913394,2.9408710467958437,0.3447912610633156,3.1141580717849924,0.6245521818790327,0.2923398612170866,0.13188385952514886,-0.17512221304650355,0.07733177575208161,0.4225314103597223,0.9141025725456303,0.473746678395286,-0.6235310490678561,0.23937792178355133,1.3428914236840213,0.13188385952514886,0.37082842982646413,-0.06148029559266701,0.2923398612170866,-2.0740082524478405,-0.06148029559266701,-0.03343454335768025,-0.4699677127277454,0.0498499651371408,0.5747486913303033,0.3447912610633156,0.10467597056101892,-0.08967050071108885,-0.2039047156366997,0.39674143767950243,0.23937792178355133,-0.350125356105606,-0.6861725882485472,3.281841750088034,-0.14649000038336524,2.0525300254302943,0.4225314103597223,0.18589586847145548,-1.1456872992127736,-0.2328390217993925,-0.17512221304650355,-0.7814856320202566,-0.5615918989070766,-0.350125356105606,-0.7814856320202566,-0.1180065861783075,-3.1850832781614544,0.10467597056101892,0.18589586847145548,0.673901466516914,-0.350125356105606,1.7398321727024608,-0.2328390217993925,3.587597806701549,0.2923398612170866,-0.1180065861783075,-0.14649000038336524,-0.8136248100970255,0.7228043903765459,0.18589586847145548,0.747090864182487,-0.5003402500028168,-0.06148029559266701,1.3211587294181275,-0.2911692129463672,-0.43976167580769304,0.747090864182487,0.7953385242734627,-0.7495318851344548,-0.7495318851344548,0.673901466516914,-0.2911692129463672,1.0303037635203478,0.4225314103597223,0.2923398612170866,-0.5615918989070766,-0.350125356105606,0.0498499651371408,-0.17512221304650355,0.18589586847145548,-0.37984219227896826,-0.06148029559266701,0.4481994586006217,-0.06148029559266701,1.386093528320324,-0.5308810490428666,0.07733177575208161,-0.6861725882485472,-0.06148029559266701,2.0714733698385936,-0.4097204049195783,-0.2911692129463672,-0.14649000038336524,-0.1180065861783075,-0.005531837066441173,-0.06148029559266701,4.50404309487471,0.3447912610633156,-0.5003402500028168,2.2206204495029636,2.745005746127423,0.5496741112974982,0.2127025180887077,4.224818104379722,-0.350125356105606,0.23937792178355133,1.5136414157872253,0.15895673427969537,-0.654763070997487,0.10467597056101892,0.5244829444562599,-0.5308810490428666,-0.2328390217993925,2.275479978158442,-0.2619266677946719,-0.9111757607706441,-1.9147862223575949,-0.43976167580769304,0.15895673427969537,0.5496741112974982,-1.4263717244472445,-0.14649000038336524,-1.2492972789568666,5.198120334434664,0.6492831048866388,0.2923398612170866,0.4225314103597223,1.5762892971839588,0.2923398612170866,0.6245521818790327,-0.08967050071108885,-0.5308810490428666,1.4289490678170462,0.10467597056101892,1.3645361307346424,2.090348997439926,-0.4097204049195783,-0.06148029559266701,0.4481994586006217,0.4481994586006217,1.0532456836169948,0.5997077106006617,4.890473754334426,-0.2619266677946719,0.5496741112974982,0.3447912610633156,0.4481994586006217,-0.4097204049195783,1.9567810941536743,-0.08967050071108885,0.2659233011870234,0.473746678395286,-0.5924746168808616,0.8431585826801586,-0.005531837066441173,0.18589586847145548,0.10467597056101892,0.4225314103597223,0.07733177575208161,-1.3548673355819485,0.2923398612170866
2,702
Azurophil granule
20
64
3.082589
0.002052
P42785,P16278,O00560,P61916,Q92820,P06280,P10619,P06865,P15586,P07602,O15260,Q07065,P17900,Q9H7Z7,Q9BTY2,O00584,O95721,P07437,P11279,P68371
Localization
GO Cellular component
msigdb_gocc
0,128,130,142,282,149,163,168,174,57,59,320,70,350,230,103,104,105,236,124
1925,130,103,2475,59,1357,926,1496,2144,104,2586,582,149,168,560,105,57,1096,701,463,163,1049,236,174,128,70,2191,1877,1179,0,2394,1989,2197,738,1831,2297,938,1882,2655,142,124,1181,1107,1730,320,348,1947,1999,750,637,548,282,1395,2348,1076,2210,530,230,1038,350,2583,880,1296,1706
-0.43976167580769304,1.6176488501837785,1.8395473434978173,-0.9440776667177786,2.419034532533944,-0.1180065861783075,0.15895673427969537,-0.2039047156366997,-0.5924746168808616,1.8395473434978173,-1.2492972789568666,0.4481994586006217,1.4925940643576996,1.4075642865122227,0.473746678395286,1.8395473434978173,2.436706104734128,0.0498499651371408,0.3447912610633156,0.5997077106006617,1.4289490678170462,0.07733177575208161,1.0988376535312658,1.386093528320324,1.638208714171853,2.2572569188414064,-0.6235310490678561,-0.4097204049195783,-0.005531837066441173,6.217718739388483,-0.8136248100970255,-0.4699677127277454,-0.6235310490678561,0.31862879037972053,-0.37984219227896826,-0.7177615370892623,0.15895673427969537,-0.4097204049195783,-1.7599354012543078,1.5554884161976426,1.6586894203500797,-0.005531837066441173,0.0498499651371408,-0.32056824010222307,0.8431585826801586,0.7953385242734627,-0.43976167580769304,-0.4699677127277454,0.31862879037972053,0.4225314103597223,0.49917415125399284,0.9608846498386505,-0.1180065861783075,-0.7495318851344548,0.07733177575208161,-0.6235310490678561,0.5244829444562599,1.1440456767678313,0.10467597056101892,0.7953385242734627,-1.2145462814230732,0.2127025180887077,-0.06148029559266701,-0.2911692129463672
2,702
Lipid localization
18
64
3.040451
0.002362
Q6P1A2,Q9BQE5,Q8WTV0,P17900,P23786,Q9H4L5,O43772,P61916,Q99720,P35790,Q8NB49,Q14108,Q9H6V9,P14174,O15118,P07602,O15260,P08183
Processes and pathways
GO Biological process
msigdb_gobp
164,37,69,70,88,100,10,142,14,237,146,19,51,218,24,57,59,189
389,2695,24,59,267,10,1131,615,1557,819,341,1874,443,583,560,57,1096,2251,189,2669,218,70,669,860,88,1463,2361,412,1776,1366,2688,237,2193,142,2267,1107,1839,19,484,1288,1999,164,2053,2100,146,1637,69,1643,14,37,915,1482,1648,2104,2059,1915,100,51,880,1296,455,576,2022,1548
0.698408241052304,-4.8821959377233615,3.530739879481159,2.419034532533944,1.0072634916981495,4.396604319498196,0.02222921008355008,0.4225314103597223,-0.2328390217993925,0.23937792178355133,0.7953385242734627,-0.4097204049195783,0.6245521818790327,0.4481994586006217,0.473746678395286,2.436706104734128,0.0498499651371408,-0.6861725882485472,1.3428914236840213,-2.0740082524478405,1.1888758808001145,2.2572569188414064,0.37082842982646413,0.2127025180887077,2.0525300254302943,-0.17512221304650355,-0.7814856320202566,0.673901466516914,-0.350125356105606,-0.1180065861783075,-3.1850832781614544,1.0988376535312658,-0.6235310490678561,1.5554884161976426,-0.6861725882485472,0.0498499651371408,-0.37984219227896826,4.111237733873485,0.5747486913303033,-0.06148029559266701,-0.4699677127277454,1.4289490678170462,-0.5003402500028168,-0.5308810490428666,1.5136414157872253,-0.2619266677946719,2.275479978158442,-0.2619266677946719,4.199796153109882,2.9887072724789827,0.18589586847145548,-0.17512221304650355,-0.2619266677946719,-0.5308810490428666,-0.5003402500028168,-0.4097204049195783,1.8789142803170127,2.7283466065358986,0.2127025180887077,-0.06148029559266701,0.6245521818790327,0.473746678395286,-0.4699677127277454,-0.2039047156366997
2,702
Organelle subcompartment
73
316
3.035682
0.0024
Q9BTU6,O00560,P30519,Q8IV08,Q70UQ0,Q9NZ08,Q16706,O60568,P09601,Q04323,O00264,P20645,Q13190,Q99720,Q6NUM9,Q8TCT8,Q9Y282,P07099,Q14108,Q8NB49,P24390,O00461,Q96HY6,P10321,Q9P2E9,Q16850,Q8NBN3,Q5BJF2,O95249,Q6NUQ4,P43307,P38435,Q6P1A2,Q9BQE5,Q9NPR9,O95487,Q96JJ7,P09497,Q15084,P48449,Q14789,O43852,P52292,P37268,Q9P2W9,Q9Y5M8,P09496,O15260,Q9UNZ2,Q96PC5,Q07065,Q8N2H4,Q9BRR6,O75844,Q86XL3,A0FGR8,Q9UBV2,O95197,Q9BUN8,O95674,O14578,Q9HD20,Q14739,Q9NRR5,Q9H4L5,Q15904,Q15392,Q8N2K0,O60725,P50402,Q8WWQ0,P11717,P55735
Localization
GO Cellular component
msigdb_gocc
264,130,3,4,133,135,132,136,137,259,255,268,269,14,400,144,145,18,19,146,21,266,276,376,423,26,150,28,279,419,160,413,164,37,166,167,307,409,432,43,431,179,300,53,310,312,424,59,328,324,320,199,336,74,206,389,351,214,215,341,338,252,359,362,100,234,112,113,114,367,119,120,380
389,1658,255,614,790,2691,266,2143,130,1301,338,535,1975,555,1868,1449,791,1927,2183,2476,59,727,2074,1928,1359,1978,1493,179,460,1601,136,114,1412,645,2353,2225,557,1457,74,2575,2032,855,664,1092,1498,214,279,1264,2291,648,1557,167,819,341,2382,2586,443,2414,1047,1875,1220,18,2325,732,424,409,137,376,120,561,1051,702,479,895,268,2257,669,2415,21,480,671,1718,2389,2260,734,3,2118,2390,1366,2037,766,53,413,1179,1420,1612,160,2264,1940,1723,43,2500,2193,1941,1674,1421,2394,367,900,1724,2418,1832,1180,300,1278,2044,2368,1834,1882,380,1058,2334,674,2546,1784,1785,1280,1425,2124,1680,2623,2200,1885,628,2203,2301,769,941,2127,1994,1573,2399,654,2602,259,677,320,2641,828,862,1514,1110,1626,679,1516,1996,269,2445,1629,829,19,430,484,359,431,1473,1737,1738,432,1287,596,112,1632,710,1893,1846,804,234,132,26,2309,1581,746,28,1527,545,1383,2096,2097,1476,2052,400,982,419,164,2053,1850,773,133,1897,1239,986,833,206,1240,4,870,2208,1158,199,113,836,1159,527,1068,146,507,150,637,1795,716,1796,528,2466,2101,144,717,1586,992,1196,119,547,777,1070,1954,872,2449,1695,1481,1244,2310,1395,2666,955,276,307,2491,1245,324,1591,639,1911,14,1801,2507,1592,37,336,1037,915,264,215,1482,2620,531,782,878,2104,1344,1038,1916,100,958,2109,2019,252,1701,1702,166,514,2574,362,787,1402,2172,1651,2173,135,1253,609,1296,423,310,882,660,642,351,611,643,2412,2176,1004,1760,328,145,2243,2179,2319,1128,2244,1864,312,1811,2673,726,1548
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2,702
Steroid binding
10
20
3.021489
0.002515
P38435,P30536,Q9H4L5,O00264,P61916,Q14108,P45880,O15118,O15173,P21796
Functions
GO Molecular function
msigdb_gomf
413,412,100,255,142,19,23,24,187,31
255,24,187,557,664,443,968,820,31,669,860,412,413,23,142,19,1643,1648,2104,100
1.0303037635203478,3.530739879481159,1.3428914236840213,0.473746678395286,0.37082842982646413,0.6245521818790327,0.13188385952514886,0.23937792178355133,3.281841750088034,0.37082842982646413,0.2127025180887077,0.673901466516914,0.673901466516914,3.587597806701549,1.5554884161976426,4.111237733873485,-0.2619266677946719,-0.2619266677946719,-0.5308810490428666,1.8789142803170127
2,702
Mitochondrial envelope
72
263
3.005092
0.002655
Q99595,Q9NS69,O75964,O00264,P09601,O43772,Q9BPX6,Q8N4H5,P11310,Q9UDX5,P14406,P45880,P21796,Q9NX63,P00403,P30536,O75600,O95831,P06576,Q99623,P43304,Q13423,Q14790,Q70HW3,O96000,O75880,Q9H2D1,Q14318,Q9Y2R0,Q9Y277,Q9NQZ5,O43169,Q567V2,Q13505,Q9BYT8,Q9BVV7,Q9NQG6,Q00796,Q69YU5,Q6P4A7,Q8N0X7,P22830,Q9BYD6,O75431,Q15388,P23786,P56385,Q8NBU5,Q9Y5J7,O95674,Q9Y3B7,Q15070,Q16891,Q14197,P52815,O00584,P18031,P13073,Q9NR28,Q9BUK6,O95139,P56134,Q96AY3,O14786,O60313,Q96NB2,Q9UBX3,P22695,Q8N983,Q9H2W6,Q6DKK2,O43676
Localization
GO Cellular component
msigdb_gocc
5,6,256,255,137,10,139,138,141,148,22,23,31,290,35,412,291,39,292,436,42,177,303,49,172,296,184,430,56,329,60,61,63,64,452,451,195,466,204,75,333,81,469,461,86,88,347,488,493,341,492,224,485,483,357,103,479,477,253,108,474,369,509,242,363,511,516,122,384,251,126,127
2142,255,790,1708,103,2695,242,852,1764,1450,1660,61,729,127,925,10,363,1601,888,1361,730,461,2324,646,291,1458,889,296,1136,256,1091,966,474,856,1415,1499,818,1931,2658,819,341,39,172,699,2586,35,1048,292,2292,666,1267,1311,137,1876,1268,765,141,1980,1098,1816,477,22,1669,1270,479,2149,1771,649,31,1717,2190,122,81,1053,88,621,896,1272,2362,412,1719,2364,1366,672,1317,540,1015,936,1824,1466,1468,1612,42,23,1370,1615,2394,2331,1571,1017,1277,357,2645,704,2088,1572,369,347,1509,940,827,741,1728,1182,2398,861,1786,466,2158,1471,1283,1110,1111,1996,2650,177,64,483,430,303,224,977,86,908,2504,1379,544,1998,485,1190,867,63,2571,1117,1118,204,126,713,75,1065,774,2572,2001,49,504,714,1951,1387,1240,2465,682,989,1692,333,138,1159,384,2132,488,2235,1743,2101,1640,2674,1162,1955,808,809,509,1338,2635,2665,954,572,2506,511,1247,2008,2593,1076,5,436,139,781,1036,2520,2010,108,1482,451,2409,846,2012,469,452,2103,1204,2314,184,1915,251,2429,606,1294,1859,2636,607,608,2509,2280,1918,785,195,60,253,1295,787,6,1165,757,961,290,1346,880,1807,1808,532,2643,516,721,148,1297,694,812,576,2023,329,1545,56,2651,2243,2071,2286,492,2320,1546,644,1490,493,884,1084,697,1971
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2,702
Golgi apparatus
29
143
2.988829
0.0028
P16278,Q6NT16,Q16706,P09601,O15439,Q8IXU6,Q13190,P24390,Q9NWM8,Q8NBN3,Q8N4Q0,Q92896,Q9HB40,Q5VW38,Q9NPR9,Q8IZA0,P50897,O15260,O15212,Q5KU26,O43760,O00231,Q96C57,Q5BKZ1,Q02818,P80303,O14976,P11717,Q9HD45
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
128,7,132,137,267,12,269,21,153,150,157,158,29,30,166,178,52,59,188,66,73,209,229,227,244,118,117,120,265
1658,459,2686,1812,209,266,535,1975,117,1927,2476,188,1869,59,1600,267,728,1359,2113,73,1601,441,1412,816,645,2290,965,1498,340,2414,1605,137,2358,2146,120,128,669,21,1608,2116,2261,1937,2037,540,1420,2264,2498,1723,1421,2394,379,900,1057,52,2332,1782,1278,2044,2368,769,118,2127,427,244,2641,828,1514,269,1185,1232,431,2306,132,227,66,1383,30,2625,1999,7,2052,982,419,657,2054,1850,945,983,2234,1952,2207,2100,1290,12,1333,178,2164,157,2447,150,1389,1030,1121,1335,1586,777,158,2467,529,2449,1695,229,2469,1398,1643,2541,349,1648,1915,2061,2013,958,1806,29,470,265,166,2574,787,1861,1402,153,2172,1210,642,1297,694,643,2175,920,471,2180,726
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2,702
Exopeptidase activity
12
28
2.968327
0.002994
P42785,P10619,Q9NZ08,O75976,O14773,Q9UIQ6,Q9H3G5,O75844,Q86TI2,Q92820,P55786,Q9HB40
Functions
GO Molecular function
msigdb_gomf
0,163,135,196,201,45,44,74,332,282,92,29
201,74,196,343,1815,163,2652,2389,1984,936,0,92,2400,1113,1897,332,282,1481,2311,2210,44,2013,29,879,693,1404,135,45
1.255425828169697,2.2206204495029636,1.2774266291404368,0.7953385242734627,-0.37984219227896826,1.4289490678170462,-1.7218791207703874,-0.8136248100970255,-0.4699677127277454,0.15895673427969537,6.217718739388483,2.0144383197469633,-0.8136248100970255,0.0498499651371408,-0.4097204049195783,0.8193015508006276,0.9608846498386505,-0.17512221304650355,-0.7177615370892623,-0.6235310490678561,2.827512784417395,-0.4699677127277454,3.341494967883903,0.2127025180887077,0.37082842982646413,-0.1180065861783075,1.5970092420957023,2.827512784417395
2,702
Transport
109
437
2.951358
0.003164
P20290,P84103,Q99595,Q9NS69,Q6NT16,Q9P0J0,O43772,Q9BVK6,Q8IXU6,Q93050,Q99720,Q8TB61,Q7Z3B4,P24390,P45880,O15118,Q5JRA6,Q9Y2T2,P21796,P00403,Q9BQE5,Q70HW3,Q6N075,O43169,Q13505,Q9Y487,Q6P4A7,Q9H2H9,Q15388,P23786,Q9H4L5,A6NIH7,Q9H0H5,O95721,P41440,P11717,P22695,P46379,Q6DKK2,O43676,Q8N4H5,Q9BPX6,P61916,Q9Y282,Q8NB49,Q13432,Q9C0H2,O95487,Q9H089,O96000,Q9H2D1,P08183,P53985,Q8N2H4,Q8NFH4,A0AVF1,O95197,Q9BUN8,Q15904,Q9HD20,Q07955,O75964,O15439,P20645,Q13190,O00461,Q12769,O43396,O95249,P06576,P52292,Q9P2W9,Q12768,Q9Y277,P53680,P49321,O15397,P56385,P22626,P82979,P51790,P56134,Q9Y5K8,Q9BVL2,P55735,P50542,Q9Y5X3,Q9H814,A0FGR8,P12270,O43823,Q9P2E9,Q13769,P61421,Q9Y3E0,Q9BVV7,O60749,Q9Y6M1,Q9HD26,Q9BTX1,O75431,Q92945,Q9Y5J7,O95139,Q96L92,Q96NB2,Q9UN86,Q8N1F7,Q9UBX3
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
498,500,5,6,7,532,10,531,12,529,14,528,525,21,23,24,545,554,31,35,37,49,58,61,64,78,75,84,86,88,100,101,102,104,115,120,122,123,126,127,138,139,142,145,146,161,165,167,171,172,184,189,192,199,212,208,214,215,234,252,260,256,267,268,269,266,280,277,279,292,300,310,308,329,318,317,313,347,345,358,368,369,388,385,380,379,406,402,389,394,390,423,418,414,457,451,442,472,470,468,461,489,493,474,510,511,517,506,516
208,389,101,1549,1925,1410,1812,2142,1867,614,1550,1492,266,1708,2322,1926,535,2522,1868,852,1764,1411,1355,1927,24,2183,2476,313,267,2184,61,1976,1928,277,853,814,729,2113,815,127,925,926,887,1978,10,1131,390,928,615,1360,442,1412,888,580,2144,1361,730,1456,2225,461,2185,646,763,854,889,1136,256,1663,1555,1092,1498,474,856,1415,1499,214,818,1176,279,1931,1009,1557,167,2658,104,1711,2382,172,699,35,1874,764,968,1462,1048,292,189,969,666,891,2669,1097,120,1980,1098,394,1223,702,2326,1771,1503,498,2482,1561,268,823,1772,31,1717,669,860,2190,345,122,1417,88,21,621,896,1463,1272,1719,1776,2364,2688,2037,2327,1565,1015,898,1879,1986,1780,1611,115,1568,1469,2518,23,123,2264,1370,1723,2193,1941,317,1421,1276,590,2331,379,1831,1422,1724,2418,1832,368,2042,1017,300,1423,1227,2044,2368,318,192,1834,1943,1944,1991,1882,380,369,347,705,2334,674,1784,1280,2157,1425,414,1680,142,2200,2487,1228,2126,1726,2301,1837,358,500,2127,1786,2267,1107,1471,260,1840,1684,1230,1514,308,280,679,1516,1996,269,1842,2047,2048,161,64,864,1788,418,1378,944,1947,1062,1473,596,86,1632,710,1893,1686,234,866,908,633,544,1998,2505,1190,1288,2519,1116,545,868,1790,1383,1329,126,58,7,713,982,2053,75,49,1385,2696,1691,525,1239,2581,2465,2100,834,12,807,1158,506,199,138,836,2447,146,1637,948,2235,1030,212,1391,1392,1479,528,2101,1121,1586,992,1797,2057,599,1242,1195,1122,1196,1480,777,2699,1031,1198,1641,489,873,529,2449,1695,752,1852,875,2665,1956,840,955,1908,1074,510,511,841,1589,1440,956,639,1643,1034,5,14,550,640,754,139,37,781,915,468,215,1482,531,385,451,1341,1647,1648,1342,878,783,2104,689,719,2136,165,171,102,1038,2238,2379,1751,184,84,691,1915,1916,100,402,1294,1535,608,2019,252,470,1701,2138,1650,6,2381,1040,2062,1594,1251,1863,880,1252,532,2217,423,310,882,1254,1654,516,721,611,1348,575,1213,812,2411,1042,2412,2176,1704,2022,517,1298,1004,1705,329,145,1215,1968,554,2319,1128,457,2072,2678,78,1043,493,884,388,1598,1707,1811,406,1084,726,2616,697,1216,472,789,1971
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2,702
Oxidoreductase
23
152
2.945725
0.003222
Q9BY49,P30519,O94788,O60568,P09601,P11310,P48735,Q16850,Q8N8N7,Q7Z4W1,Q8N4Q0,P30837,O95831,Q8NBX0,P43304,Q96LJ7,O75874,Q8NB78,Q32P28,O15254,O15460,Q9UHG3,Q15392
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
129,3,8,136,137,141,17,26,27,156,157,33,39,41,42,50,54,55,68,72,89,95,112
2142,2143,1301,1449,72,89,2029,1133,136,1454,1552,1361,730,646,54,2032,8,39,2382,930,2188,1219,700,2586,286,792,1932,375,2292,970,137,620,1221,141,1222,2597,2147,477,173,793,2294,2384,2698,1558,1051,1771,1717,2190,650,2036,2150,934,1272,2361,1877,1273,2295,1013,3,33,1719,2363,2153,1464,1564,936,1939,2328,1468,42,17,2556,2194,2681,1615,2331,2196,1180,1942,1833,2043,2087,2088,770,466,2158,2302,654,677,2269,1149,1626,742,1842,2204,2423,484,359,2624,274,112,1846,804,908,503,26,2505,68,746,1117,597,1476,400,657,205,681,1154,945,2001,1156,156,2208,1794,157,27,55,2132,41,1744,2674,1746,953,955,50,1076,1644,1801,422,349,129,2059,606,2636,2109,2684,2173,660,2493,788,95,1657,2179
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2,702
Protease
16
74
2.942081
0.00326
P42785,P10619,Q99538,Q9NZ08,P28074,O75976,Q9UIQ6,Q9H3G5,O75844,Q8TCT8,P42892,Q86UV5,Q16740,Q96K76,P55786,Q9HB40
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
0,163,99,135,38,196,45,44,74,144,80,183,25,90,92,29
1300,2321,201,1007,2324,74,196,967,2189,1815,163,2652,2552,622,38,2389,1984,2670,1567,937,0,80,1613,2296,2394,2645,1227,2396,2419,92,1785,769,2662,1113,2161,303,1737,25,1581,546,1791,2537,1897,332,183,144,717,1954,1199,1587,874,2007,90,2311,876,1247,284,2593,99,780,452,44,2013,2014,29,879,693,1404,135,848,45,725,644,2026
-0.08967050071108885,-0.7495318851344548,1.255425828169697,0.10467597056101892,-0.7495318851344548,2.2206204495029636,1.2774266291404368,0.13188385952514886,-0.6235310490678561,-0.37984219227896826,1.4289490678170462,-1.7218791207703874,-1.1115742979561345,0.4225314103597223,2.9568654023721628,-0.8136248100970255,-0.4699677127277454,-2.0740082524478405,-0.2328390217993925,0.15895673427969537,6.217718739388483,2.202206192643275,-0.2619266677946719,-0.7177615370892623,-0.8136248100970255,-1.646530754259767,-0.03343454335768025,-0.8136248100970255,-0.8459514851409792,2.0144383197469633,-0.350125356105606,0.2923398612170866,-1.8756727477583501,0.0498499651371408,-0.5924746168808616,0.890558218300318,-0.32056824010222307,3.502073656744272,-0.2328390217993925,0.49917415125399284,-0.350125356105606,-1.0439690553345753,-0.4097204049195783,0.8193015508006276,1.3645361307346424,1.5346059932631821,0.3447912610633156,-0.43976167580769304,-0.005531837066441173,-0.2328390217993925,0.2127025180887077,-0.4699677127277454,2.0335184987881214,-0.7177615370892623,0.2127025180887077,-0.03343454335768025,0.9608846498386505,-1.2492972789568666,1.8789142803170127,0.2923398612170866,0.6245521818790327,2.827512784417395,-0.4699677127277454,-0.4699677127277454,3.341494967883903,0.2127025180887077,0.37082842982646413,-0.1180065861783075,1.5970092420957023,0.23937792178355133,2.827512784417395,0.3447912610633156,0.4225314103597223,-0.4699677127277454
2,702
Sensorimotor neuropathy
7
29
2.914958
0.003557
Q5KU26,P00403,O95831,Q8N2K0,Q9NSE4,Q9Y2R0,P07602
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
66,35,39,113,87,56,57
790,2074,363,39,35,968,315,57,2080,1224,2599,1468,115,1143,1833,1882,1572,1886,348,830,66,113,1198,1851,453,87,880,56,644
0.2659233011870234,-0.5308810490428666,0.747090864182487,2.9408710467958437,3.1141580717849924,0.13188385952514886,0.8431585826801586,2.436706104734128,-0.5308810490428666,-0.03343454335768025,-1.2842660323097124,-0.17512221304650355,1.7398321727024608,0.02222921008355008,-0.37984219227896826,-0.4097204049195783,-0.2328390217993925,-0.4097204049195783,0.7953385242734627,0.23937792178355133,2.329773449633904,1.7599256653622593,-0.005531837066441173,-0.37984219227896826,0.6245521818790327,2.0714733698385936,0.2127025180887077,2.489366453233105,0.4225314103597223
2,702
RNA recognition motif domain [IPR000504]
54
110
2.909456
0.003621
P23588,O60506,P84103,P52597,Q07955,Q8IY67,P31943,P08579,Q9UHX1,P35637,Q9BWF3,P98175,Q13243,Q12849,P23246,P07910,P09012,Q15056,Q86U42,P43243,P38159,Q9P2N5,P31942,P52756,Q14103,P51991,Q96T37,O75494,Q96I25,Q9UKM9,Q92879,O43390,Q9Y6M1,Q01085,O14979,P78332,Q86V81,Q08170,Q15424,P62995,P22626,P11940,P19338,Q16629,P98179,Q13242,Q9UN86,Q8NDT2,Q96PK6,Q99729,Q9BY77,Q13247,Q01844,Q92804
Sequence
InterPro Domain
interpro_domain
378,496,500,626,260,776,395,393,553,155,687,416,802,801,411,293,408,543,305,796,176,438,298,673,570,566,450,558,449,723,600,314,472,331,330,706,598,593,709,465,345,585,344,633,106,370,517,245,246,247,783,249,382,250
885,1492,330,1086,963,314,927,496,558,1662,1095,293,393,1606,408,891,585,1817,1715,344,345,411,378,971,1363,1985,298,395,1178,155,176,2392,796,825,566,1018,626,673,799,1783,465,706,500,416,106,331,382,2618,260,593,801,1021,1022,370,802,249,2047,1112,1732,570,1430,1187,904,1024,543,831,1474,709,1234,907,633,1633,980,1950,305,598,947,776,2344,2003,245,1161,2167,911,250,600,914,449,246,450,1339,247,687,783,996,997,1000,1403,1251,1863,1211,438,553,1169,723,517,1082,1005,1707,472
0.18589586847145548,-0.2039047156366997,0.8193015508006276,0.0498499651371408,0.13188385952514886,0.8431585826801586,0.15895673427969537,0.5496741112974982,0.473746678395286,-0.2911692129463672,0.0498499651371408,0.9141025725456303,0.698408241052304,-0.2619266677946719,0.673901466516914,0.18589586847145548,0.4481994586006217,-0.37984219227896826,-0.32056824010222307,0.7953385242734627,0.7953385242734627,0.673901466516914,0.7228043903765459,0.13188385952514886,-0.1180065861783075,-0.4699677127277454,0.890558218300318,0.698408241052304,-0.005531837066441173,1.4714633126430223,1.386093528320324,-0.8136248100970255,0.2659233011870234,0.23937792178355133,0.473746678395286,0.10467597056101892,0.4225314103597223,0.37082842982646413,0.2659233011870234,-0.350125356105606,0.5997077106006617,0.3447912610633156,0.5496741112974982,0.673901466516914,1.8395473434978173,0.8193015508006276,0.7228043903765459,-1.3905052682383434,1.0303037635203478,0.4481994586006217,0.2659233011870234,0.10467597056101892,0.10467597056101892,0.747090864182487,0.2659233011870234,1.0532456836169948,-0.5003402500028168,0.0498499651371408,-0.32056824010222307,0.473746678395286,-0.14649000038336524,-0.005531837066441173,0.18589586847145548,0.10467597056101892,0.49917415125399284,0.23937792178355133,-0.17512221304650355,0.3447912610633156,-0.03343454335768025,0.18589586847145548,0.4225314103597223,-0.2619266677946719,0.13188385952514886,-0.43976167580769304,0.890558218300318,0.4481994586006217,0.15895673427969537,0.2923398612170866,-0.7495318851344548,-0.4699677127277454,1.0760900505966375,0.02222921008355008,-0.5924746168808616,0.18589586847145548,1.0532456836169948,0.4481994586006217,0.18589586847145548,0.6245521818790327,1.0760900505966375,0.6245521818790327,-0.08967050071108885,1.0760900505966375,0.37082842982646413,0.2923398612170866,0.13188385952514886,0.13188385952514886,0.13188385952514886,-0.1180065861783075,-0.03343454335768025,-0.37984219227896826,-0.005531837066441173,0.6492831048866388,0.49917415125399284,0.02222921008355008,0.3447912610633156,0.5496741112974982,0.07733177575208161,0.13188385952514886,-0.2911692129463672,0.5997077106006617
2,702
Membrane lipid metabolic process
8
30
2.908622
0.00363
P16278,Q8NCC3,P17900,Q8NBX0,Q13510,P50897,P06280,P07602
Processes and pathways
GO Biological process
msigdb_gobp
128,134,70,41,111,52,149,57
727,2074,648,443,582,149,168,57,1096,128,70,669,1314,52,677,111,1380,867,41,134,1954,2666,1591,1801,753,1651,2173,880,1253,1296
0.31862879037972053,-0.5308810490428666,0.39674143767950243,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,2.436706104734128,0.0498499651371408,1.638208714171853,2.2572569188414064,0.37082842982646413,-0.08967050071108885,2.678047917700652,0.37082842982646413,1.7799433878907398,-0.1180065861783075,0.2127025180887077,2.876397384907642,1.5970092420957023,-0.43976167580769304,-1.9147862223575949,-0.2328390217993925,-0.350125356105606,0.31862879037972053,-0.2619266677946719,-0.5924746168808616,0.2127025180887077,-0.03343454335768025,-0.06148029559266701
2,702
Glycosphingolipid metabolism
6
15
2.880712
0.003968
P16278,P10619,P17900,Q13510,P06280,P07602
Processes and pathways
Reactome Pathways
msigdb_reactome
128,163,70,111,149,57
389,926,443,149,168,57,1096,163,128,70,111,1380,915,1651,880
0.698408241052304,0.15895673427969537,0.6245521818790327,1.4925940643576996,1.4075642865122227,2.436706104734128,0.0498499651371408,1.4289490678170462,1.638208714171853,2.2572569188414064,1.7799433878907398,-0.1180065861783075,0.18589586847145548,-0.2619266677946719,0.2127025180887077
2,702
Oxidase
6
18
2.8792
0.003987
O15254,P11310,Q15067,P14406,O15260,O43169
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
72,141,274,22,59,61
72,59,61,296,1268,141,1223,22,1669,649,934,936,1615,274,804,945,2001,606
2.2389705497371217,2.419034532533944,2.365660090880429,0.890558218300318,-0.06148029559266701,1.5554884161976426,-0.03343454335768025,3.643834047397023,-0.2911692129463672,0.39674143767950243,0.15895673427969537,0.15895673427969537,-0.2619266677946719,0.9841240598522195,0.2659233011870234,0.15895673427969537,-0.4699677127277454,0.4481994586006217
2,702
Tetrapyrrole binding
7
15
2.847236
0.00441
P30519,O00264,P09601,Q8WUJ1,Q16850,O15173,O43169
Functions
GO Molecular function
msigdb_gomf
3,255,137,13,26,187,61
255,187,61,666,137,1052,3,26,681,504,13,1799,1202,350,2020
1.0303037635203478,1.3428914236840213,2.365660090880429,0.37082842982646413,1.5762892971839588,0.07733177575208161,5.249303056100748,3.487680492801992,0.37082842982646413,0.5496741112974982,4.212322514130888,-0.350125356105606,-0.005531837066441173,0.7953385242734627,-0.4699677127277454
2,702
Endoplasmic reticulum lumen
23
50
2.833429
0.004605
Q9NZ08,O60568,O75718,Q9NWM8,Q5JRA6,P30040,Q15084,P13674,O43852,Q07065,Q32P28,P14314,Q15293,Q13217,O15460,Q9Y680,Q9BTY2,Q7Z4H8,O00584,Q9P2K2,Q96AY3,Q02818,Q14257
Localization
GO Cellular component
msigdb_gocc
135,136,518,153,545,538,432,173,179,320,68,444,82,348,89,221,230,361,103,372,509,244,116
103,89,926,179,136,518,930,858,2293,2146,667,173,444,561,1502,2035,2388,671,1718,2191,538,734,1365,1016,740,244,320,348,116,1735,432,82,68,545,361,833,750,1071,509,955,1037,1443,230,2620,153,1347,135,372,1447,221
1.8395473434978173,2.0335184987881214,0.15895673427969537,1.3645361307346424,1.5762892971839588,0.5244829444562599,0.15895673427969537,0.2127025180887077,-0.7177615370892623,-0.5924746168808616,0.37082842982646413,1.386093528320324,0.6245521818790327,0.473746678395286,-0.2039047156366997,-0.5003402500028168,-0.8136248100970255,0.37082842982646413,-0.32056824010222307,-0.6235310490678561,0.49917415125399284,0.31862879037972053,-0.1180065861783075,0.10467597056101892,0.31862879037972053,1.0760900505966375,0.8431585826801586,0.7953385242734627,1.7398321727024608,-0.32056824010222307,0.6492831048866388,2.183727349455117,2.293640144931326,0.49917415125399284,0.7712686001756313,0.23937792178355133,0.31862879037972053,0.07733177575208161,0.5496741112974982,0.15895673427969537,0.10467597056101892,-0.14649000038336524,1.1440456767678313,-1.3905052682383434,1.4925940643576996,-0.08967050071108885,1.5970092420957023,0.747090864182487,-0.14649000038336524,1.1888758808001145
2,702
Cellular lipid metabolic process
30
178
2.833265
0.004608
P16278,Q9NPH0,Q9BY49,Q8NCC3,O94788,Q9Y263,P61916,P11310,P07099,Q8NHP8,P06280,Q8N8N7,Q9HB40,Q8N4Q0,Q6P1A2,Q8NBX0,P48449,Q13011,P50897,P37268,O75874,P07602,Q8WTV0,P17900,O15254,O75844,P23786,Q9BWD1,Q13510,Q8N2K0
Processes and pathways
GO Biological process
msigdb_gobp
128,1,129,134,8,140,142,141,18,147,149,27,29,157,164,41,43,48,52,53,54,57,69,70,72,74,88,94,111,113
1658,2585,923,2182,2691,2695,1301,555,1450,72,727,2074,1131,1601,1551,2353,557,1008,1457,1497,74,54,8,664,2291,648,819,341,2382,443,582,583,2693,1604,149,168,18,57,1096,2079,141,2597,1223,218,1713,2384,2698,1558,128,1051,70,1312,669,860,88,1504,934,1563,1463,2361,1877,1313,1314,1776,1366,237,53,1986,1468,1101,1140,2039,2518,43,2500,2194,1615,379,52,2086,1180,1833,2297,798,1572,2089,142,1107,1229,2399,1839,677,1149,482,1110,48,2697,111,2402,2624,274,1189,830,2050,1114,804,908,1434,1740,503,1380,2309,2446,746,867,1999,1476,400,164,2053,773,2001,2131,2626,113,157,27,1068,2132,41,134,637,147,69,1744,2674,1070,1954,1746,1338,2666,1439,1589,1591,2492,436,1644,1801,753,2507,264,2620,94,2508,129,2104,350,606,29,2109,1,1959,787,1402,2171,2172,1651,2173,880,1253,1296,351,1297,1923,576,140,2179,494
-0.2911692129463672,-1.2492972789568666,0.15895673427969537,-0.6235310490678561,-4.143157661047852,-4.8821959377233615,-0.08967050071108885,0.473746678395286,-0.17512221304650355,2.2389705497371217,0.31862879037972053,-0.5308810490428666,0.02222921008355008,-0.2619266677946719,-0.2328390217993925,-0.7814856320202566,0.473746678395286,0.10467597056101892,-0.17512221304650355,-0.2039047156366997,2.2206204495029636,2.558767311500275,4.492217400733412,0.37082842982646413,-0.7177615370892623,0.39674143767950243,0.23937792178355133,0.7953385242734627,-0.8136248100970255,0.6245521818790327,0.4481994586006217,0.4481994586006217,-4.501064891738855,-0.2619266677946719,1.4925940643576996,1.4075642865122227,4.111237733873485,2.436706104734128,0.0498499651371408,-0.5308810490428666,1.5554884161976426,-1.2842660323097124,-0.03343454335768025,1.1888758808001145,-0.32056824010222307,-0.8136248100970255,-5.288752019977064,-0.2328390217993925,1.638208714171853,0.07733177575208161,2.2572569188414064,-0.08967050071108885,0.37082842982646413,0.2127025180887077,2.0525300254302943,-0.2039047156366997,0.15895673427969537,-0.2328390217993925,-0.17512221304650355,-0.7814856320202566,-0.4097204049195783,-0.08967050071108885,-0.08967050071108885,-0.350125356105606,-0.1180065861783075,1.0988376535312658,2.6102209682067175,-0.4699677127277454,-0.17512221304650355,0.0498499651371408,0.02222921008355008,-0.5003402500028168,-1.0104720506565676,2.827512784417395,-0.977175681919584,-0.6235310490678561,-0.2619266677946719,0.7228043903765459,2.678047917700652,-0.5308810490428666,-0.005531837066441173,-0.37984219227896826,-0.7177615370892623,0.2659233011870234,-0.2328390217993925,-0.5308810490428666,1.5554884161976426,0.0498499651371408,-0.03343454335768025,-0.8136248100970255,-0.37984219227896826,0.37082842982646413,0.02222921008355008,0.5747486913303033,0.0498499651371408,2.745005746127423,-5.150367307121161,1.7799433878907398,-0.8136248100970255,-1.4263717244472445,0.9841240598522195,-0.005531837066441173,0.23937792178355133,-0.5003402500028168,0.0498499651371408,0.2659233011870234,0.18589586847145548,-0.14649000038336524,-0.32056824010222307,0.5496741112974982,-0.1180065861783075,-0.7177615370892623,-0.8784677570852006,0.31862879037972053,0.2127025180887077,-0.4699677127277454,-0.17512221304650355,0.698408241052304,1.4289490678170462,-0.5003402500028168,0.2923398612170866,-0.4699677127277454,-0.5615918989070766,-1.4263717244472445,1.7599256653622593,1.4714633126430223,3.385787138944637,0.07733177575208161,-0.5615918989070766,2.876397384907642,1.5970092420957023,0.4225314103597223,1.5136414157872253,2.275479978158442,-0.32056824010222307,-2.1553332825055893,0.07733177575208161,-0.43976167580769304,-0.32056824010222307,-0.08967050071108885,-1.9147862223575949,-0.14649000038336524,-0.2328390217993925,-0.2328390217993925,-0.9440776667177786,0.6492831048866388,-0.2619266677946719,-0.350125356105606,0.31862879037972053,-0.977175681919584,1.0303037635203478,-1.3905052682383434,1.9567810941536743,-0.977175681919584,1.638208714171853,-0.5308810490428666,0.7953385242734627,0.4481994586006217,3.341494967883903,-0.5308810490428666,6.184106568144779,-0.43976167580769304,0.2923398612170866,-0.1180065861783075,-0.5924746168808616,-0.5924746168808616,-0.2619266677946719,-0.5924746168808616,0.2127025180887077,-0.03343454335768025,-0.06148029559266701,0.7953385242734627,-0.06148029559266701,-0.4097204049195783,0.473746678395286,1.5762892971839588,-0.5924746168808616,0.5747486913303033
2,702
Mitochondrial protein import
7
34
2.818528
0.004824
Q13505,Q9NX63,Q99595,Q9NS69,Q8N4H5,Q15388,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
64,290,5,6,138,86,31
852,729,2249,461,2324,889,966,1415,699,292,666,765,1980,1098,31,896,1466,1110,64,86,1190,546,138,5,2169,451,607,6,290,812,2023,1490,493,884
0.2127025180887077,0.31862879037972053,-0.6861725882485472,0.5997077106006617,-0.7495318851344548,0.18589586847145548,0.13188385952514886,-0.14649000038336524,0.3447912610633156,0.9141025725456303,0.37082842982646413,0.2923398612170866,-0.4699677127277454,0.0498499651371408,3.281841750088034,0.18589586847145548,-0.17512221304650355,0.0498499651371408,2.3477474020211564,2.0714733698385936,-0.005531837066441173,0.49917415125399284,1.5762892971839588,5.198120334434664,-0.5924746168808616,0.6245521818790327,0.4481994586006217,4.890473754334426,0.9375444335085626,0.2659233011870234,-0.4699677127277454,-0.17512221304650355,0.5747486913303033,0.2127025180887077
2,702
Vascular skin abnormality
14
95
2.817744
0.004836
P16278,P21964,P00403,P10619,Q08J23,O60568,Q9Y487,P51812,O75844,P22830,Q14108,Q9NWM8,P06280,Q13126
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,34,35,163,40,136,78,11,74,81,19,153,149,62
1351,1353,1263,136,1814,339,730,74,2634,1265,35,374,443,582,149,857,584,163,1010,1979,2652,586,128,1012,1769,2385,2257,1716,1717,34,81,671,2528,2191,2119,1776,1564,1367,935,898,2038,413,1780,2460,1369,2500,1941,2194,1143,1180,2042,11,1834,2088,1677,2127,1147,1683,654,1839,677,2268,40,655,62,19,1891,1324,359,632,977,1234,710,1846,1383,2406,713,2053,524,178,435,2236,872,1339,2210,755,2059,1958,153,918,660,696,813,78,1598
-0.1180065861783075,-0.1180065861783075,-0.06148029559266701,1.5762892971839588,-0.37984219227896826,0.7953385242734627,0.31862879037972053,2.2206204495029636,-1.5353706399979128,-0.06148029559266701,3.1141580717849924,0.7228043903765459,0.6245521818790327,0.4481994586006217,1.4925940643576996,0.2127025180887077,0.4481994586006217,1.4289490678170462,0.10467597056101892,-0.4699677127277454,-1.7218791207703874,0.4481994586006217,1.638208714171853,0.10467597056101892,-0.350125356105606,-0.8136248100970255,-0.6861725882485472,-0.32056824010222307,-0.32056824010222307,3.1296283127460667,2.183727349455117,0.37082842982646413,-1.0439690553345753,-0.6235310490678561,-0.5615918989070766,-0.350125356105606,-0.2328390217993925,-0.1180065861783075,0.15895673427969537,0.18589586847145548,-0.5003402500028168,0.673901466516914,-0.350125356105606,-0.9111757607706441,-0.1180065861783075,-0.977175681919584,-0.43976167580769304,-0.6235310490678561,0.02222921008355008,-0.005531837066441173,-0.5003402500028168,4.3359171716292355,-0.37984219227896826,-0.5308810490428666,-0.2911692129463672,-0.5615918989070766,0.02222921008355008,-0.2911692129463672,0.39674143767950243,-0.37984219227896826,0.37082842982646413,-0.6861725882485472,2.892590824162729,0.39674143767950243,2.365660090880429,4.111237733873485,-0.4097204049195783,-0.08967050071108885,0.7712686001756313,0.4225314103597223,0.13188385952514886,-0.03343454335768025,0.3447912610633156,-0.37984219227896826,-0.1180065861783075,-0.8136248100970255,0.3447912610633156,-0.5003402500028168,0.5244829444562599,1.386093528320324,0.6492831048866388,-0.654763070997487,0.2127025180887077,-0.08967050071108885,-0.6235310490678561,0.31862879037972053,-0.5003402500028168,-0.43976167580769304,1.4925940643576996,0.18589586847145548,0.39674143767950243,0.37082842982646413,0.2659233011870234,2.2206204495029636,-0.2328390217993925
2,702
Peptidase activity
25
103
2.813555
0.0049
P42785,Q9NZ08,Q8TCT8,Q99436,Q92820,Q16740,Q9HB40,P28070,P10619,P28074,Q9UIQ6,Q9H3G5,Q14790,Q86UV5,P49721,O75976,O14773,Q99496,O75844,Q86TI2,P42892,Q96K76,P55786,Q99538,P22695
Functions
GO Molecular function
msigdb_gomf
0,135,144,284,282,25,29,159,163,38,45,44,303,183,67,196,201,335,74,332,80,90,92,99,122
1300,2321,201,1870,1007,2324,74,196,1091,967,343,2189,1815,163,2652,2114,2552,733,122,1936,159,622,38,2389,1984,734,2670,936,1567,937,0,80,1613,2296,1988,67,2394,2590,2645,1227,2396,2419,92,800,1785,769,2662,1110,2400,655,1113,2161,303,1737,25,1581,1847,546,1791,2052,2163,2537,1792,1897,332,183,144,717,548,1954,282,872,1199,1587,874,1481,2007,90,2311,876,1247,284,335,2593,99,780,2210,877,452,44,2013,2014,29,2109,879,693,1404,135,848,45,725,644,2026
-0.08967050071108885,-0.7495318851344548,1.255425828169697,-0.4097204049195783,0.10467597056101892,-0.7495318851344548,2.2206204495029636,1.2774266291404368,0.0498499651371408,0.13188385952514886,0.7953385242734627,-0.6235310490678561,-0.37984219227896826,1.4289490678170462,-1.7218791207703874,-0.5615918989070766,-1.1115742979561345,0.31862879037972053,1.6586894203500797,-0.43976167580769304,1.4502485272895491,0.4225314103597223,2.9568654023721628,-0.8136248100970255,-0.4699677127277454,0.31862879037972053,-2.0740082524478405,0.15895673427969537,-0.2328390217993925,0.15895673427969537,6.217718739388483,2.202206192643275,-0.2619266677946719,-0.7177615370892623,-0.4699677127277454,2.293640144931326,-0.8136248100970255,-1.2492972789568666,-1.646530754259767,-0.03343454335768025,-0.8136248100970255,-0.8459514851409792,2.0144383197469633,0.2659233011870234,-0.350125356105606,0.2923398612170866,-1.8756727477583501,0.0498499651371408,-0.8136248100970255,0.39674143767950243,0.0498499651371408,-0.5924746168808616,0.890558218300318,-0.32056824010222307,3.502073656744272,-0.2328390217993925,-0.37984219227896826,0.49917415125399284,-0.350125356105606,-0.5003402500028168,-0.5924746168808616,-1.0439690553345753,-0.350125356105606,-0.4097204049195783,0.8193015508006276,1.3645361307346424,1.5346059932631821,0.3447912610633156,0.49917415125399284,-0.43976167580769304,0.9608846498386505,0.2127025180887077,-0.005531837066441173,-0.2328390217993925,0.2127025180887077,-0.17512221304650355,-0.4699677127277454,2.0335184987881214,-0.7177615370892623,0.2127025180887077,-0.03343454335768025,0.9608846498386505,0.8193015508006276,-1.2492972789568666,1.8789142803170127,0.2923398612170866,-0.6235310490678561,0.2127025180887077,0.6245521818790327,2.827512784417395,-0.4699677127277454,-0.4699677127277454,3.341494967883903,-0.5308810490428666,0.2127025180887077,0.37082842982646413,-0.1180065861783075,1.5970092420957023,0.23937792178355133,2.827512784417395,0.3447912610633156,0.4225314103597223,-0.4699677127277454
2,702
Mitochondrial transmembrane transport
12
46
2.811578
0.00493
Q99595,O75964,P06576,O95831,O43772,Q9BPX6,Q6P4A7,Q9H2D1,Q15388,P23786,P56385,P21796
Processes and pathways
GO Biological process
msigdb_gobp
5,256,292,39,10,139,75,184,86,88,347,31
852,729,10,888,2324,889,1136,256,966,818,2658,39,699,1048,292,765,1980,1098,31,88,621,896,1015,1370,369,347,1786,86,1190,75,2235,2101,1640,2665,511,5,139,781,451,184,1294,607,812,576,644,1084
0.2127025180887077,0.31862879037972053,4.396604319498196,0.18589586847145548,-0.7495318851344548,0.18589586847145548,0.02222921008355008,1.0303037635203478,0.13188385952514886,0.23937792178355133,-1.8368287909913394,2.9408710467958437,0.3447912610633156,0.07733177575208161,0.9141025725456303,0.2923398612170866,-0.4699677127277454,0.0498499651371408,3.281841750088034,2.0525300254302943,0.4225314103597223,0.18589586847145548,0.10467597056101892,-0.1180065861783075,0.747090864182487,0.7953385242734627,-0.350125356105606,2.0714733698385936,-0.005531837066441173,2.2206204495029636,-0.654763070997487,-0.5308810490428666,-0.2619266677946719,-1.9147862223575949,0.5496741112974982,5.198120334434664,1.5762892971839588,0.2923398612170866,0.6245521818790327,1.3645361307346424,-0.06148029559266701,0.4481994586006217,0.2659233011870234,0.473746678395286,0.4225314103597223,0.07733177575208161
2,702
Regulation of blood pressure
6
15
2.810306
0.004949
P42785,Q9NZ08,P09601,Q9UIQ6,P42892,Q9HB40
Processes and pathways
GO Biological process
msigdb_gobp
0,135,137,45,80,29
792,968,197,137,2597,1503,0,80,2086,1323,1850,29,135,45,406
0.2659233011870234,0.13188385952514886,1.2774266291404368,1.5762892971839588,-1.2842660323097124,-0.2039047156366997,6.217718739388483,2.202206192643275,-0.5308810490428666,-0.08967050071108885,-0.37984219227896826,3.341494967883903,1.5970092420957023,2.827512784417395,0.698408241052304
2,702
protein modifying enzyme
7
19
2.806335
0.005011
Q15418,O60568,P51812,P13674,O60725,P50897,O15460
Functions
Panther Protein class
panther_protein_class
2,136,11,173,114,52,89
2143,1763,1660,89,136,1551,114,518,173,52,11,654,1626,1631,2,2642,272,1912,1491
-0.5924746168808616,-0.350125356105606,-0.2911692129463672,2.0335184987881214,1.5762892971839588,-0.2328390217993925,1.7398321727024608,0.5244829444562599,1.386093528320324,2.678047917700652,4.3359171716292355,0.39674143767950243,-0.2619266677946719,-0.2619266677946719,5.468469224387756,-1.6092322015717255,1.0072634916981495,-0.4097204049195783,-0.17512221304650355
2,702
Rhoa gtpase cycle
10
38
2.789795
0.005274
P30519,Q9H0H5,Q15904,Q13190,P41440,Q96HY6,Q8NBN3,O15173,P02786,O14578
Processes and pathways
Reactome Pathways
msigdb_reactome
3,102,234,269,115,276,150,187,343,338
1925,338,187,2184,1661,965,1264,343,1269,894,1463,3,115,1828,1368,1722,1941,1832,2395,974,269,803,743,359,234,2051,833,150,1196,838,1395,276,102,1080,1650,1208,609,552
-0.43976167580769304,0.7953385242734627,1.3428914236840213,-0.6235310490678561,-0.2911692129463672,0.13188385952514886,-0.06148029559266701,0.7953385242734627,-0.06148029559266701,0.18589586847145548,-0.17512221304650355,5.249303056100748,1.7398321727024608,-0.37984219227896826,-0.1180065861783075,-0.32056824010222307,-0.43976167580769304,-0.37984219227896826,-0.8136248100970255,0.13188385952514886,1.0072634916981495,0.2659233011870234,0.31862879037972053,0.7712686001756313,1.1214892721063172,-0.5003402500028168,0.23937792178355133,1.4925940643576996,-0.005531837066441173,0.23937792178355133,-0.1180065861783075,0.9841240598522195,1.8592673659235324,0.07733177575208161,-0.2619266677946719,-0.005531837066441173,0.4481994586006217,0.49917415125399284
2,702
Lipase activity
6
15
2.789537
0.005278
Q8IV08,Q8NCC3,P09601,Q8N2K0,Q9H6V9,Q8NHP8
Functions
GO Molecular function
msigdb_gomf
4,134,137,113,51,147
1497,2291,137,1312,1877,734,233,4,113,1068,134,147,51,1651,2246
-0.2039047156366997,-0.7177615370892623,1.5762892971839588,-0.08967050071108885,-0.4097204049195783,0.31862879037972053,1.1214892721063172,5.2288928568634425,1.7599256653622593,0.07733177575208161,1.5970092420957023,1.5136414157872253,2.7283466065358986,-0.2619266677946719,-0.654763070997487
2,702
Nuclear outer membrane endoplasmic reticulum membrane network
57
262
2.780651
0.005425
O00560,P30519,Q8IV08,Q70UQ0,Q9NZ08,Q04323,O60568,P09601,O00264,P10321,Q13190,Q6NUM9,Q99720,A0FGR8,Q8TCT8,Q9Y282,P07099,Q14108,Q8NB49,P24390,Q96HY6,Q9P2E9,Q16850,Q6NUQ4,Q5BJF2,P43307,P38435,Q6P1A2,Q9BQE5,O95487,Q96JJ7,P48449,O43852,P52292,P37268,Q9P2W9,Q9Y5M8,O15260,Q96PC5,Q07065,Q9BRR6,O75844,Q86XL3,Q9UBV2,O95197,Q9BUN8,O95674,Q14739,Q9NRR5,Q9H4L5,Q15904,Q15392,Q8N2K0,O60725,P50402,Q9HD20,P55735
Localization
GO Cellular component
msigdb_gocc
130,3,4,133,135,259,136,137,255,376,269,400,14,389,144,145,18,19,146,21,276,423,26,419,28,160,413,164,37,167,307,43,179,300,53,310,312,59,324,320,336,74,206,351,214,215,341,359,362,100,234,112,113,114,367,252,380
389,1658,255,614,790,2143,130,1301,535,1975,555,1449,791,1355,1927,59,727,2074,1928,1359,179,460,1601,136,114,2353,2225,557,74,2575,2032,855,664,1092,1498,214,1264,648,1557,167,819,341,2382,2586,2414,1047,1875,1220,2596,18,2325,732,137,376,561,1051,702,479,895,669,2415,21,480,671,1718,2260,734,3,2118,2390,1366,2037,766,53,413,1179,1612,1469,160,1940,1723,43,2500,2193,1941,1674,1421,2394,590,367,1724,1832,1180,300,2044,2368,1834,1882,380,1058,2334,674,2546,1785,1280,1425,2124,1680,2623,2200,2487,1885,628,2203,2301,769,941,654,2602,259,677,320,828,862,1626,1516,1996,269,2445,829,19,430,484,359,1737,1738,432,596,112,1632,710,1893,1846,804,234,26,2309,746,28,1527,545,2096,1476,2052,400,982,419,164,2053,1850,773,133,1897,1239,986,833,206,1240,4,870,2208,113,836,1159,527,1068,146,507,637,1795,716,1796,528,2466,2101,144,717,1121,1586,992,1196,547,1070,1954,872,1695,1481,1244,2310,1395,2666,955,276,307,1245,324,1591,639,14,1801,2507,37,336,1037,915,215,1482,2620,531,2104,1038,1916,100,958,2109,2019,252,1701,1702,514,362,787,1402,1651,2173,135,1253,609,1296,423,310,882,660,642,351,611,643,2412,2176,1760,145,2243,2179,2319,1128,2244,1864,1598,312,2673,726,1548
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2,702
Lipid metabolic process
43
235
2.77822
0.005466
P16278,Q9NPH0,Q9BY49,Q8NCC3,O94788,Q9Y263,P61916,P11310,P07099,Q8NHP8,O15118,P06280,Q16850,Q8N8N7,Q9HB40,Q8N4Q0,P21964,Q6P1A2,Q9BQE5,P06865,Q8NBX0,P48449,Q13011,Q9H6V9,P50897,P37268,O75874,P07602,P53985,Q8WTV0,P17900,O15254,O14773,O75844,P23786,P14174,Q9BWD1,Q99538,Q9H4L5,P38571,Q13510,Q15392,Q8N2K0
Processes and pathways
GO Biological process
msigdb_gobp
128,1,129,134,8,140,142,141,18,147,24,149,26,27,29,157,34,164,37,168,41,43,48,51,52,53,54,57,192,69,70,72,201,74,88,218,94,99,100,233,111,112,113
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2,702
Envelope
107
416
2.777121
0.005484
Q99595,Q9NS69,O43772,Q99720,P14406,P45880,O15118,Q5BJF2,P21796,P00403,O95831,P43304,Q70HW3,Q9Y2R0,Q9NQZ5,O43169,Q567V2,Q13505,Q6P4A7,O75844,P22830,Q15388,P23786,Q9H4L5,O00584,P07437,Q9BUK6,P80303,P11717,P22695,Q6DKK2,O43676,O00560,P09601,Q8N4H5,Q9BPX6,P11310,Q9UDX5,Q13423,O96000,Q9H2D1,O15173,Q9NQG6,Q69YU5,Q8NFH4,Q15070,Q96C57,O14786,Q8NDT2,Q9NR28,Q9H2W6,Q8IXM6,O75964,O00264,Q12769,Q9NX63,O75600,P06576,Q14790,P49454,O75880,Q9Y277,P45973,O15397,Q8N0X7,Q9Y2U8,P56385,O95674,Q14739,P52815,P56134,P50402,O60313,Q9BVL2,Q8N983,P55735,P02545,Q6NUM9,P12270,P67809,P30536,Q99623,Q03252,Q14318,Q96T37,Q9BYT8,Q9BVV7,Q00796,Q9BTX1,Q9BYD6,P62995,O95619,O75431,Q8NBU5,Q9Y5J7,Q9Y3B7,Q16891,Q14197,P18031,P13073,O95139,Q96AY3,Q96NB2,Q8N1F7,Q9NQC3,Q9UBX3,P20700
Localization
GO Cellular component
msigdb_gocc
5,6,10,14,22,23,24,28,31,35,39,42,49,56,60,61,63,64,75,74,81,86,88,100,103,105,108,118,120,122,126,127,130,137,138,139,141,148,177,172,184,187,195,204,212,224,229,242,245,253,251,263,256,255,280,290,291,292,303,299,296,329,316,313,333,353,347,341,359,357,369,367,363,385,384,380,374,400,394,415,412,436,428,430,450,452,451,466,468,469,465,462,461,488,493,492,485,483,479,477,474,509,511,506,514,516,499
1549,2142,255,1867,1550,790,1708,2322,130,103,1926,2695,1975,242,1449,852,1764,1355,24,187,1450,1660,313,61,814,729,815,698,127,925,10,363,1601,888,1361,730,461,2324,646,1414,291,1497,1458,763,889,74,296,1136,256,1091,2032,966,474,856,1415,1499,818,1931,1009,2658,819,462,341,39,172,699,2586,35,374,1932,1048,292,2596,2292,105,666,1267,2563,1311,137,1876,2357,584,1268,765,141,120,2551,1980,1098,394,1816,477,2114,22,1669,1270,479,1559,2149,1771,649,499,31,1717,2190,122,81,1053,88,621,896,2388,671,1272,2362,412,1719,2364,1366,672,1317,2327,540,1015,936,2701,1824,1879,1466,1468,1828,1368,1612,1469,2518,796,42,797,23,316,1721,1370,299,1615,2394,1276,590,2331,1881,367,738,1571,1017,1423,1277,357,2645,1227,938,704,2088,1991,1572,380,369,347,1058,1509,705,2487,2126,465,2301,415,1837,118,940,827,741,1728,1182,2398,861,1786,466,2158,1471,2602,428,1283,1110,2400,280,1111,1996,2650,568,1184,177,64,483,944,430,359,303,1473,224,977,86,908,2504,1379,544,1998,485,1190,867,63,28,1475,1382,868,1790,2571,1236,1117,1118,204,126,713,400,75,1065,774,945,2572,2001,49,504,714,525,1951,1387,986,1898,1240,2465,682,1290,989,1692,263,1903,333,506,138,1159,384,2132,488,245,1638,2235,212,1391,1795,1743,2101,1121,992,1242,1122,1640,547,1480,2674,1162,1031,1955,808,809,2310,509,1338,229,2635,875,2665,954,572,2506,1245,511,841,1439,639,450,1247,2008,2593,1076,718,1034,5,436,14,1801,2210,139,781,1036,1443,468,2520,2010,108,1482,2011,385,451,1341,2409,846,2012,469,452,2103,1957,2104,2136,1204,2314,2238,184,1915,251,2429,100,606,1294,1859,2636,607,1124,608,2509,2280,1918,785,514,195,60,253,1650,1295,787,6,1040,2214,1165,757,961,290,1651,1346,880,1252,1807,1808,1253,532,1296,2643,848,660,1654,516,721,148,1297,694,919,575,1213,883,812,576,1042,1704,1760,1966,2023,329,1545,56,2651,353,2243,2071,2286,492,2320,1546,2072,2244,644,1490,2245,493,884,1598,1044,1084,697,1971
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2,702
Outer membrane
24
78
2.770221
0.005602
Q9NS69,O00264,P09601,Q8N4H5,Q6NUM9,Q99720,P45880,P21796,Q9NX63,P30536,Q99623,Q14790,Q9Y277,Q9NQZ5,O43169,Q13505,Q9NQG6,Q8N0X7,O75431,Q15388,Q8NBU5,Q9BUK6,P50402,O60313
Localization
GO Cellular component
msigdb_gocc
6,255,137,138,400,14,23,31,290,412,436,303,329,60,61,64,195,333,461,86,488,108,367,363
255,790,2695,61,363,1601,461,966,819,699,2586,2596,1311,137,2149,31,412,1366,1824,1466,1612,1469,23,2394,367,1277,1572,1509,2487,1283,2650,64,303,977,86,1379,485,867,1117,1118,400,774,2572,1951,682,989,1692,333,138,1159,488,1743,547,808,572,2008,1076,436,14,108,1482,1204,785,195,60,787,6,1165,757,290,1651,880,660,694,329,2071,1490,697
1.0303037635203478,0.2659233011870234,-4.8821959377233615,2.365660090880429,0.747090864182487,-0.2619266677946719,0.5997077106006617,0.13188385952514886,0.23937792178355133,0.3447912610633156,-1.2492972789568666,-1.2842660323097124,-0.08967050071108885,1.5762892971839588,-0.5924746168808616,3.281841750088034,0.673901466516914,-0.1180065861783075,-0.37984219227896826,-0.17512221304650355,-0.2619266677946719,-0.17512221304650355,3.587597806701549,-0.8136248100970255,0.747090864182487,-0.06148029559266701,-0.2328390217993925,-0.2039047156366997,-0.9440776667177786,-0.06148029559266701,-1.6840786597335329,2.3477474020211564,0.890558218300318,0.13188385952514886,2.0714733698385936,-0.1180065861783075,0.5747486913303033,0.2127025180887077,0.0498499651371408,0.0498499651371408,0.698408241052304,0.2923398612170866,-1.1800104648843361,-0.43976167580769304,0.37082842982646413,0.13188385952514886,-0.2911692129463672,0.8193015508006276,1.5762892971839588,0.02222921008355008,0.5747486913303033,-0.32056824010222307,0.49917415125399284,0.2659233011870234,0.473746678395286,-0.4699677127277454,0.07733177575208161,0.6492831048866388,4.199796153109882,1.8197536917866635,-0.17512221304650355,-0.005531837066441173,0.2923398612170866,1.2993373623907043,2.3835119137294205,0.2923398612170866,4.890473754334426,0.02222921008355008,0.31862879037972053,0.9375444335085626,-0.2619266677946719,0.2127025180887077,0.39674143767950243,0.37082842982646413,0.8431585826801586,-0.5003402500028168,-0.17512221304650355,0.37082842982646413
2,702
Sterol metabolic process
9
32
2.751987
0.005923
Q6P1A2,Q9BQE5,Q8WTV0,P48449,P61916,Q15392,P37268,O15118,Q16850
Processes and pathways
GO Biological process
msigdb_gobp
164,37,69,43,142,112,53,24,26
24,557,2032,664,2586,443,1222,1713,1051,2190,53,233,2039,43,1615,2297,142,2267,1229,2402,484,359,2050,112,1846,804,26,164,69,37,660,455
3.530739879481159,0.473746678395286,-0.5003402500028168,0.37082842982646413,-1.2492972789568666,0.6245521818790327,-0.03343454335768025,-0.32056824010222307,0.07733177575208161,-0.6235310490678561,2.6102209682067175,1.1214892721063172,-0.5003402500028168,2.827512784417395,-0.2619266677946719,-0.7177615370892623,1.5554884161976426,-0.6861725882485472,-0.03343454335768025,-0.8136248100970255,0.5747486913303033,0.7712686001756313,-0.5003402500028168,1.7599256653622593,-0.37984219227896826,0.2659233011870234,3.487680492801992,1.4289490678170462,2.275479978158442,2.9887072724789827,0.39674143767950243,0.6245521818790327
2,702
RNA-binding domain superfamily [IPR035979]
53
122
2.745117
0.006049
P23588,O60506,P84103,P52597,Q07955,Q9UKV3,P31943,P08579,Q9UHX1,Q71RC2,P35637,Q9BWF3,Q9BXP5,P98175,P23246,P07910,P09012,Q9BZI7,Q15056,Q86U42,Q9P2N5,P38159,P31942,P52756,Q14103,P51991,Q96T37,O75494,Q96I25,Q9UKM9,Q92879,O43390,Q9Y6M1,Q01085,O14979,P78332,Q86V81,Q08170,Q9Y2U8,P62995,P22626,P11940,P19338,Q16629,P98179,Q13242,Q9UN86,Q8NDT2,Q96PK6,Q99729,Q13247,Q01844,Q92804
Sequence
InterPro Superfamily
interpro_homologous_superfamily
378,496,500,626,260,533,395,393,553,420,155,687,688,416,411,293,408,689,543,305,438,176,298,673,570,566,450,558,449,723,600,314,472,331,330,706,598,593,353,465,345,585,344,633,106,370,517,245,246,247,249,382,250
885,1492,330,1086,963,314,927,496,558,1662,1265,1095,293,393,1606,408,891,585,1817,1715,344,345,411,378,971,1363,1985,298,395,1178,155,176,2392,796,825,566,1018,626,673,799,1783,465,706,500,416,106,331,382,2444,2618,260,593,801,1021,1022,370,802,249,2047,1112,1732,570,1430,1187,904,1024,543,831,1474,709,1234,907,633,1633,980,420,1950,305,598,947,776,2344,2003,245,1391,1161,2167,911,2004,250,600,914,449,246,450,1339,247,2312,687,688,783,996,689,997,1536,1000,1403,1251,1863,1211,438,1654,553,1169,723,533,517,353,1082,1005,1707,472
0.18589586847145548,-0.2039047156366997,0.8193015508006276,0.0498499651371408,0.13188385952514886,0.8431585826801586,0.15895673427969537,0.5496741112974982,0.473746678395286,-0.2911692129463672,-0.06148029559266701,0.0498499651371408,0.9141025725456303,0.698408241052304,-0.2619266677946719,0.673901466516914,0.18589586847145548,0.4481994586006217,-0.37984219227896826,-0.32056824010222307,0.7953385242734627,0.7953385242734627,0.673901466516914,0.7228043903765459,0.13188385952514886,-0.1180065861783075,-0.4699677127277454,0.890558218300318,0.698408241052304,-0.005531837066441173,1.4714633126430223,1.386093528320324,-0.8136248100970255,0.2659233011870234,0.23937792178355133,0.473746678395286,0.10467597056101892,0.4225314103597223,0.37082842982646413,0.2659233011870234,-0.350125356105606,0.5997077106006617,0.3447912610633156,0.5496741112974982,0.673901466516914,1.8395473434978173,0.8193015508006276,0.7228043903765459,-0.8784677570852006,-1.3905052682383434,1.0303037635203478,0.4481994586006217,0.2659233011870234,0.10467597056101892,0.10467597056101892,0.747090864182487,0.2659233011870234,1.0532456836169948,-0.5003402500028168,0.0498499651371408,-0.32056824010222307,0.473746678395286,-0.14649000038336524,-0.005531837066441173,0.18589586847145548,0.10467597056101892,0.49917415125399284,0.23937792178355133,-0.17512221304650355,0.3447912610633156,-0.03343454335768025,0.18589586847145548,0.4225314103597223,-0.2619266677946719,0.13188385952514886,0.673901466516914,-0.43976167580769304,0.890558218300318,0.4481994586006217,0.15895673427969537,0.2923398612170866,-0.7495318851344548,-0.4699677127277454,1.0760900505966375,-0.1180065861783075,0.02222921008355008,-0.5924746168808616,0.18589586847145548,-0.4699677127277454,1.0532456836169948,0.4481994586006217,0.18589586847145548,0.6245521818790327,1.0760900505966375,0.6245521818790327,-0.08967050071108885,1.0760900505966375,-0.7177615370892623,0.37082842982646413,0.37082842982646413,0.2923398612170866,0.13188385952514886,0.37082842982646413,0.13188385952514886,-0.2039047156366997,0.13188385952514886,-0.1180065861783075,-0.03343454335768025,-0.37984219227896826,-0.005531837066441173,0.6492831048866388,-0.2619266677946719,0.49917415125399284,0.02222921008355008,0.3447912610633156,0.5244829444562599,0.5496741112974982,0.7953385242734627,0.07733177575208161,0.13188385952514886,-0.2911692129463672,0.5997077106006617
2,702
Molecular transducer activity
9
29
2.738342
0.006175
Q5KU26,Q8WTV0,Q99720,O14786,Q14108,Q9BUN8,O15118,O15173,P11717
Functions
GO Molecular function
msigdb_gomf
66,69,14,242,19,215,24,187,120
242,663,24,187,1304,619,2358,120,268,412,2460,2194,1511,902,482,975,19,1893,1686,522,66,1850,69,2467,14,215,423,611,643
1.0760900505966375,0.37082842982646413,3.530739879481159,1.3428914236840213,-0.08967050071108885,0.4225314103597223,-0.7814856320202566,1.6994156728204817,1.0072634916981495,0.673901466516914,-0.9111757607706441,-0.6235310490678561,-0.2039047156366997,0.18589586847145548,0.5747486913303033,0.13188385952514886,4.111237733873485,-0.4097204049195783,-0.2911692129463672,0.5244829444562599,2.329773449633904,-0.37984219227896826,2.275479978158442,-0.9111757607706441,4.199796153109882,1.2111511761503668,0.673901466516914,0.4481994586006217,0.4225314103597223
2,702
Sphingolipid metabolic process
7
25
2.701978
0.006893
P16278,Q8NCC3,P17900,Q13510,P50897,P06280,P07602
Processes and pathways
GO Biological process
msigdb_gobp
128,134,70,111,52,149,57
727,2074,648,443,149,168,57,1096,128,70,669,1314,52,677,111,1380,867,134,2666,753,1651,2173,880,1253,1296
0.31862879037972053,-0.5308810490428666,0.39674143767950243,0.6245521818790327,1.4925940643576996,1.4075642865122227,2.436706104734128,0.0498499651371408,1.638208714171853,2.2572569188414064,0.37082842982646413,-0.08967050071108885,2.678047917700652,0.37082842982646413,1.7799433878907398,-0.1180065861783075,0.2127025180887077,1.5970092420957023,-1.9147862223575949,0.31862879037972053,-0.2619266677946719,-0.5924746168808616,0.2127025180887077,-0.03343454335768025,-0.06148029559266701
2,702
Peptide binding
22
61
2.684902
0.007255
P10321,Q14978,Q9NZ08,O00264,P24390,P09497,Q9UIQ6,P52292,P09496,O15212,Q8WTV0,O14773,Q99471,P42892,Q9H7Z7,Q15388,P55786,P40855,Q9UHV9,Q15392,Q9BVL2,P50542
Functions
GO Molecular function
msigdb_gomf
376,398,135,255,21,409,45,300,424,188,69,201,207,80,350,86,92,223,373,112,385,379
255,1550,2322,1926,201,188,2247,1304,1360,966,2414,1416,424,409,376,2552,2617,2035,21,671,1563,2362,1821,1365,2327,1938,223,80,2484,1276,590,379,300,1423,1227,92,2335,1680,2199,1726,1684,1428,1473,398,86,112,1797,69,873,1852,207,1801,385,452,1487,350,1445,135,2021,373,45
1.0303037635203478,-0.2328390217993925,-0.7495318851344548,-0.43976167580769304,1.255425828169697,1.3428914236840213,-0.6861725882485472,-0.08967050071108885,-0.1180065861783075,0.13188385952514886,-0.8459514851409792,-0.14649000038336524,0.6492831048866388,0.673901466516914,0.7228043903765459,-1.1115742979561345,-1.3905052682383434,-0.5003402500028168,3.6717230671513654,0.37082842982646413,-0.2328390217993925,-0.7814856320202566,-0.37984219227896826,-0.1180065861783075,-0.7495318851344548,-0.43976167580769304,1.1665076288666967,2.202206192643275,-0.9440776667177786,-0.06148029559266701,0.4481994586006217,0.7228043903765459,0.890558218300318,-0.14649000038336524,-0.03343454335768025,2.0144383197469633,-0.7495318851344548,-0.2911692129463672,-0.6235310490678561,-0.32056824010222307,-0.2911692129463672,-0.14649000038336524,-0.17512221304650355,0.698408241052304,2.0714733698385936,1.7599256653622593,-0.350125356105606,2.275479978158442,0.2127025180887077,-0.37984219227896826,1.255425828169697,-0.350125356105606,0.7228043903765459,0.6245521818790327,-0.17512221304650355,0.7953385242734627,-0.14649000038336524,1.5970092420957023,-0.4699677127277454,0.747090864182487,2.827512784417395
2,702
Ion transport
16
53
2.683453
0.007287
Q9C0H2,O75964,P06576,P56385,Q9H0H5,Q9Y487,Q9BPX6,Q15904,P51790,P56134,Q9H2H9,P45880,Q6N075,Q9Y277,Q9Y5K8,P21796
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
165,256,292,347,102,78,139,234,368,369,84,23,58,329,388,31
1867,1136,256,818,699,764,968,1462,292,702,1503,823,1772,31,1417,621,896,1015,898,1780,23,1370,368,2042,1943,369,347,414,2127,1062,234,1288,58,948,2235,1030,1586,529,2665,1440,639,139,165,102,84,1348,2176,329,1215,78,388,2616,789
-0.4097204049195783,0.02222921008355008,1.0303037635203478,0.23937792178355133,0.3447912610633156,0.2923398612170866,0.13188385952514886,-0.17512221304650355,0.9141025725456303,0.3447912610633156,-0.2039047156366997,0.23937792178355133,-0.350125356105606,3.281841750088034,-0.14649000038336524,0.4225314103597223,0.18589586847145548,0.10467597056101892,0.18589586847145548,-0.350125356105606,3.587597806701549,-0.1180065861783075,0.747090864182487,-0.5003402500028168,-0.43976167580769304,0.747090864182487,0.7953385242734627,0.673901466516914,-0.5615918989070766,0.07733177575208161,1.1214892721063172,-0.06148029559266701,2.436706104734128,0.15895673427969537,-0.654763070997487,0.10467597056101892,-0.2328390217993925,0.5244829444562599,-1.9147862223575949,-0.14649000038336524,0.4225314103597223,1.5762892971839588,1.4289490678170462,1.8592673659235324,2.090348997439926,-0.08967050071108885,-0.5924746168808616,0.8431585826801586,-0.005531837066441173,2.2206204495029636,0.7228043903765459,-1.3548673355819485,0.2923398612170866
2,702
Hepaticobiliary system development
8
34
2.675064
0.007472
Q15418,Q16706,O94788,P09601,P11310,O75844,P11717,P00813
Processes and pathways
GO Biological process
msigdb_gobp
2,132,8,137,141,74,120,93
1599,338,1763,1552,74,8,93,583,792,137,141,120,1979,444,587,1716,1504,1607,2488,802,1788,570,2,304,2464,132,1740,2406,2101,200,2169,604,1345,611
-0.2619266677946719,0.7953385242734627,-0.350125356105606,-0.2328390217993925,2.2206204495029636,4.492217400733412,1.9760700997311131,0.4481994586006217,0.2659233011870234,1.5762892971839588,1.5554884161976426,1.6994156728204817,-0.4699677127277454,0.6245521818790327,0.4481994586006217,-0.32056824010222307,-0.2039047156366997,-0.2619266677946719,-0.9440776667177786,0.2659233011870234,-0.350125356105606,0.473746678395286,5.468469224387756,0.890558218300318,-0.9111757607706441,1.5970092420957023,-0.32056824010222307,-0.8136248100970255,-0.5308810490428666,1.2774266291404368,-0.5924746168808616,0.4481994586006217,-0.08967050071108885,0.4481994586006217
2,702
Metabolism of lipids
27
161
2.67045
0.007575
P16278,Q9NPH0,Q9BY49,Q8IV08,Q8NCC3,O43772,P11310,P06280,Q16850,Q8N8N7,P10619,Q6P1A2,O95487,P48449,P43304,P50897,P37268,P07602,Q9NQZ5,P17900,O15254,P23786,Q9BWD1,Q99538,Q9H4L5,Q13510,Q15392
Processes and pathways
Reactome Pathways
msigdb_reactome
128,1,129,4,134,10,141,149,26,27,163,164,167,43,42,52,53,57,60,70,72,88,94,99,100,111,112
389,923,2182,2691,2695,1301,555,1450,72,727,2074,926,10,1131,1601,615,1496,2186,1008,2032,1264,648,1557,167,819,341,2382,443,2693,1604,149,168,57,1096,2079,1815,163,141,1713,2384,2698,1558,128,1012,70,587,2482,1561,1052,669,860,2190,88,1504,1313,412,1366,2688,237,1465,1824,53,413,1468,1101,1140,2039,42,43,2500,2193,2194,1615,52,1180,1833,2297,1834,1572,1425,1374,2440,2126,2580,1107,1229,2399,677,1149,482,1110,2697,111,2402,484,359,2624,1473,274,2050,262,1114,112,1632,304,1846,804,503,26,1380,2505,2446,746,867,1476,164,773,2001,2642,4,2131,1794,27,1068,134,637,1744,2674,1070,2005,2666,1439,2427,1643,99,2492,2210,2507,915,264,94,129,2104,100,350,1,1649,60,787,1402,1651,2173,880,1253,1296,660,1297,695,405,1349,494
0.698408241052304,0.15895673427969537,-0.6235310490678561,-4.143157661047852,-4.8821959377233615,-0.08967050071108885,0.473746678395286,-0.17512221304650355,2.2389705497371217,0.31862879037972053,-0.5308810490428666,0.15895673427969537,4.396604319498196,0.02222921008355008,-0.2619266677946719,0.4225314103597223,-0.2039047156366997,-0.6235310490678561,0.10467597056101892,-0.5003402500028168,-0.06148029559266701,0.39674143767950243,-0.2328390217993925,1.4075642865122227,0.23937792178355133,0.7953385242734627,-0.8136248100970255,0.6245521818790327,-4.501064891738855,-0.2619266677946719,1.4925940643576996,1.4075642865122227,2.436706104734128,0.0498499651371408,-0.5308810490428666,-0.37984219227896826,1.4289490678170462,1.5554884161976426,-0.32056824010222307,-0.8136248100970255,-5.288752019977064,-0.2328390217993925,1.638208714171853,0.10467597056101892,2.2572569188414064,0.4481994586006217,-0.9440776667177786,-0.2328390217993925,0.07733177575208161,0.37082842982646413,0.2127025180887077,-0.6235310490678561,2.0525300254302943,-0.2039047156366997,-0.08967050071108885,0.673901466516914,-0.1180065861783075,-3.1850832781614544,1.0988376535312658,-0.17512221304650355,-0.37984219227896826,2.6102209682067175,0.673901466516914,-0.17512221304650355,0.0498499651371408,0.02222921008355008,-0.5003402500028168,2.827512784417395,2.827512784417395,-0.977175681919584,-0.6235310490678561,-0.6235310490678561,-0.2619266677946719,2.678047917700652,-0.005531837066441173,-0.37984219227896826,-0.7177615370892623,-0.37984219227896826,-0.2328390217993925,-0.14649000038336524,-0.1180065861783075,-0.8784677570852006,-0.5615918989070766,-1.2145462814230732,0.0498499651371408,-0.03343454335768025,-0.8136248100970255,0.37082842982646413,0.02222921008355008,0.5747486913303033,0.0498499651371408,-5.150367307121161,1.7799433878907398,-0.8136248100970255,0.5747486913303033,0.7712686001756313,-1.4263717244472445,-0.17512221304650355,0.9841240598522195,-0.5003402500028168,1.0303037635203478,0.0498499651371408,1.7599256653622593,-0.2619266677946719,0.890558218300318,-0.37984219227896826,0.2659233011870234,0.5496741112974982,3.487680492801992,-0.1180065861783075,-0.977175681919584,-0.8784677570852006,0.31862879037972053,0.2127025180887077,-0.17512221304650355,1.4289490678170462,0.2923398612170866,-0.4699677127277454,-1.6092322015717255,5.2288928568634425,-0.5615918989070766,-0.350125356105606,3.385787138944637,0.07733177575208161,1.5970092420957023,0.4225314103597223,-0.32056824010222307,-2.1553332825055893,0.07733177575208161,-0.4699677127277454,-1.9147862223575949,-0.14649000038336524,-0.8459514851409792,-0.2619266677946719,1.8789142803170127,-0.9440776667177786,-0.6235310490678561,-0.977175681919584,0.18589586847145548,1.0303037635203478,1.9567810941536743,1.638208714171853,-0.5308810490428666,1.8789142803170127,0.7953385242734627,6.184106568144779,-0.2619266677946719,2.3835119137294205,0.2923398612170866,-0.1180065861783075,-0.2619266677946719,-0.5924746168808616,0.2127025180887077,-0.03343454335768025,-0.06148029559266701,0.39674143767950243,-0.06148029559266701,0.37082842982646413,0.698408241052304,-0.08967050071108885,0.5747486913303033
2,702
Calcium-binding protein
6
14
2.658593
0.007847
P43307,Q9BPX6,Q15293,O43852,Q14257,P80303
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
160,139,82,179,116,118
179,671,623,160,1373,397,118,244,116,82,1290,990,139,921
1.3645361307346424,0.37082842982646413,0.4225314103597223,1.4502485272895491,-0.1180065861783075,0.698408241052304,1.7196623603455143,1.0760900505966375,1.7398321727024608,2.183727349455117,-0.06148029559266701,0.13188385952514886,1.5762892971839588,0.18589586847145548
2,702
Transport of small molecules
31
147
2.653009
0.007978
P30519,P09601,O15439,Q9BPX6,P61916,Q8NB49,Q99436,P45880,O15118,P21796,P28070,Q9C0H2,P28074,Q70HW3,Q9Y277,P08183,P53985,P49721,P53680,Q8WTV0,Q9Y487,O00231,Q9H2H9,Q9UBV2,Q9BUN8,P02786,P40855,P38571,Q15904,P51790,Q9HD20
Processes and pathways
Reactome Pathways
msigdb_reactome
3,137,267,139,142,146,284,23,24,31,159,165,38,49,329,189,192,67,318,69,78,209,84,351,215,343,223,233,234,368,252
209,2352,473,614,2321,1354,24,267,1262,888,2324,557,1135,2456,664,1555,818,1711,343,764,968,1462,1048,1310,858,189,969,424,137,1010,2669,1980,1098,1011,702,1012,1099,1503,1560,733,823,1772,2516,31,1417,2387,1100,933,1936,1983,159,622,38,1463,3,2118,2688,1317,539,766,2263,540,898,233,1780,223,2329,2436,23,1830,1988,67,2590,368,2042,318,192,1943,1882,800,591,414,142,1617,2228,2299,1726,1727,653,2127,2267,1994,1183,1110,1626,1150,2445,2422,2232,2272,1686,234,1288,2053,49,1952,836,146,1638,2235,1030,528,1586,69,1640,808,529,1852,2628,1440,1247,284,2348,436,780,640,139,215,165,1038,84,252,1542,351,516,1756,1348,576,1170,1924,2511,329,1215,78,644,388,789
1.2333342498208812,-0.7814856320202566,0.5747486913303033,0.4225314103597223,-0.7495318851344548,-0.1180065861783075,3.530739879481159,1.0072634916981495,-0.06148029559266701,0.18589586847145548,-0.7495318851344548,0.473746678395286,0.02222921008355008,-0.9111757607706441,0.37082842982646413,-0.2328390217993925,0.23937792178355133,-0.32056824010222307,0.7953385242734627,0.2923398612170866,0.13188385952514886,-0.17512221304650355,0.07733177575208161,-0.08967050071108885,0.2127025180887077,1.3428914236840213,0.13188385952514886,0.6492831048866388,1.5762892971839588,0.10467597056101892,-2.0740082524478405,-0.4699677127277454,0.0498499651371408,0.10467597056101892,0.3447912610633156,0.10467597056101892,0.0498499651371408,-0.2039047156366997,-0.2328390217993925,0.31862879037972053,0.23937792178355133,-0.350125356105606,-1.0104720506565676,3.281841750088034,-0.14649000038336524,-0.8136248100970255,0.0498499651371408,0.15895673427969537,-0.43976167580769304,-0.4699677127277454,1.4502485272895491,0.4225314103597223,2.9568654023721628,-0.17512221304650355,5.249303056100748,-0.5615918989070766,-3.1850832781614544,-0.08967050071108885,0.49917415125399284,0.2923398612170866,-0.6861725882485472,0.49917415125399284,0.18589586847145548,1.1214892721063172,-0.350125356105606,1.1665076288666967,-0.7495318851344548,-0.8784677570852006,3.587597806701549,-0.37984219227896826,-0.4699677127277454,2.293640144931326,-1.2492972789568666,0.747090864182487,-0.5003402500028168,0.8431585826801586,1.3211587294181275,-0.43976167580769304,-0.4097204049195783,0.2659233011870234,0.4481994586006217,0.673901466516914,1.5554884161976426,-0.2619266677946719,-0.654763070997487,-0.7177615370892623,-0.32056824010222307,-0.32056824010222307,0.39674143767950243,-0.5615918989070766,-0.6861725882485472,-0.4699677127277454,-0.005531837066441173,0.0498499651371408,-0.2619266677946719,0.02222921008355008,-0.8784677570852006,-0.8459514851409792,-0.654763070997487,-0.6861725882485472,-0.2911692129463672,1.1214892721063172,-0.06148029559266701,-0.5003402500028168,2.745005746127423,-0.43976167580769304,0.23937792178355133,1.5136414157872253,-0.2619266677946719,-0.654763070997487,0.10467597056101892,0.5244829444562599,-0.2328390217993925,2.275479978158442,-0.2619266677946719,0.2659233011870234,0.5244829444562599,-0.37984219227896826,-1.4263717244472445,-0.14649000038336524,-0.03343454335768025,0.9608846498386505,-0.7495318851344548,0.6492831048866388,0.2923398612170866,0.4225314103597223,1.5762892971839588,1.2111511761503668,1.4289490678170462,0.10467597056101892,2.090348997439926,1.0532456836169948,-0.2039047156366997,0.7953385242734627,0.5496741112974982,-0.32056824010222307,-0.08967050071108885,0.473746678395286,0.02222921008355008,-0.4097204049195783,-0.977175681919584,0.8431585826801586,-0.005531837066441173,2.2206204495029636,0.4225314103597223,0.7228043903765459,0.2923398612170866
2,702
Oxidoreductase activity
30
209
2.649938
0.008051
Q9BY49,P30519,O94788,O60568,P09601,P11310,P48735,P14406,Q16850,Q8N8N7,Q7Z4W1,Q8N4Q0,P30837,P00403,O95831,Q8NBX0,P61457,P43304,Q13423,P13674,Q96LJ7,O75874,Q8NB78,O43169,Q32P28,O15254,O15460,Q9UHG3,Q15392,O43676
Functions
GO Molecular function
msigdb_gomf
129,3,8,136,137,141,17,22,26,27,156,157,33,35,39,41,169,42,177,173,50,54,55,61,68,72,89,95,112,127
923,2142,1599,2143,1708,1301,1449,72,267,89,61,2029,277,127,925,1813,1929,1133,136,1454,1552,1361,730,646,1457,54,2456,2032,8,474,856,1415,1499,1931,39,2382,930,172,2188,1219,700,2586,286,35,2478,792,1932,375,2292,858,970,666,2079,137,620,1667,1268,1221,141,1222,2564,2597,2147,477,667,173,1223,793,22,2294,2384,2698,1558,1051,1771,649,1717,2190,650,2036,2150,934,2565,1563,1272,2361,1877,1273,2295,1013,734,3,33,1719,2363,2364,2153,1464,1564,936,1986,1939,2328,1468,42,366,17,2556,2194,2681,1615,2331,2196,1180,1942,1833,1017,2043,2087,2088,1572,169,770,466,2158,2302,654,677,2269,1149,1626,742,1842,2204,177,2423,484,359,2624,274,432,112,1846,804,908,544,1998,503,26,2505,68,219,746,1117,597,1476,400,657,205,2000,681,1154,945,2001,504,1156,156,2208,1794,157,27,55,2132,41,658,1744,2674,1746,953,955,307,50,2593,1076,1644,1801,1749,422,349,129,2059,1916,350,606,2636,2109,2684,2173,532,660,2493,788,721,95,1657,2241,2243,2179,1971
0.15895673427969537,-0.5924746168808616,-0.2619266677946719,-0.5924746168808616,-0.32056824010222307,-0.08967050071108885,-0.17512221304650355,2.2389705497371217,1.0072634916981495,2.0335184987881214,2.365660090880429,-0.5003402500028168,0.9608846498386505,1.638208714171853,0.15895673427969537,-0.37984219227896826,-0.43976167580769304,0.02222921008355008,1.5762892971839588,-0.17512221304650355,-0.2328390217993925,-0.1180065861783075,0.31862879037972053,0.39674143767950243,-0.17512221304650355,2.558767311500275,-0.9111757607706441,-0.5003402500028168,4.492217400733412,0.5747486913303033,0.2127025180887077,-0.14649000038336524,-0.2039047156366997,-0.43976167580769304,2.9408710467958437,-0.8136248100970255,0.15895673427969537,1.386093528320324,-0.6235310490678561,-0.03343454335768025,0.3447912610633156,-1.2492972789568666,0.9375444335085626,3.1141580717849924,-0.9440776667177786,0.2659233011870234,-0.43976167580769304,0.7228043903765459,-0.7177615370892623,0.2127025180887077,0.13188385952514886,0.37082842982646413,-0.5308810490428666,1.5762892971839588,0.4225314103597223,-0.2911692129463672,-0.06148029559266701,-0.03343454335768025,1.5554884161976426,-0.03343454335768025,-1.1456872992127736,-1.2842660323097124,-0.5924746168808616,0.5747486913303033,0.37082842982646413,1.386093528320324,-0.03343454335768025,0.2659233011870234,3.643834047397023,-0.7177615370892623,-0.8136248100970255,-5.288752019977064,-0.2328390217993925,0.07733177575208161,-0.350125356105606,0.39674143767950243,-0.32056824010222307,-0.6235310490678561,0.39674143767950243,-0.5003402500028168,-0.5924746168808616,0.15895673427969537,-1.1456872992127736,-0.2328390217993925,-0.06148029559266701,-0.7814856320202566,-0.4097204049195783,-0.06148029559266701,-0.7177615370892623,0.10467597056101892,0.31862879037972053,5.249303056100748,3.160430985084966,-0.32056824010222307,-0.7814856320202566,-0.7814856320202566,-0.5924746168808616,-0.17512221304650355,-0.2328390217993925,0.15895673427969537,-0.4699677127277454,-0.43976167580769304,-0.7495318851344548,-0.17512221304650355,2.827512784417395,0.747090864182487,4.123983608212495,-1.1115742979561345,-0.6235310490678561,-2.5804238826626027,-0.2619266677946719,-0.7495318851344548,-0.6235310490678561,-0.005531837066441173,-0.43976167580769304,-0.37984219227896826,0.10467597056101892,-0.5003402500028168,-0.5308810490428666,-0.5308810490428666,-0.2328390217993925,1.4075642865122227,0.2923398612170866,0.5997077106006617,-0.5924746168808616,-0.7177615370892623,0.39674143767950243,0.37082842982646413,-0.6861725882485472,0.02222921008355008,-0.2619266677946719,0.31862879037972053,-0.37984219227896826,-0.6235310490678561,1.386093528320324,-0.8459514851409792,0.5747486913303033,0.7712686001756313,-1.4263717244472445,0.9841240598522195,0.6492831048866388,1.7599256653622593,-0.37984219227896826,0.2659233011870234,0.18589586847145548,0.49917415125399284,-0.4699677127277454,0.5496741112974982,3.487680492801992,-0.977175681919584,2.293640144931326,1.1888758808001145,0.31862879037972053,0.0498499651371408,0.4481994586006217,-0.17512221304650355,0.698408241052304,0.39674143767950243,1.255425828169697,-0.4699677127277454,0.37082842982646413,0.02222921008355008,0.15895673427969537,-0.4699677127277454,0.5496741112974982,0.02222921008355008,1.4714633126430223,-0.6235310490678561,-0.350125356105606,1.4714633126430223,3.385787138944637,2.5415030973697146,-0.5615918989070766,2.876397384907642,0.39674143767950243,-0.32056824010222307,-2.1553332825055893,-0.32056824010222307,0.15895673427969537,0.15895673427969537,0.890558218300318,2.7283466065358986,-1.2492972789568666,0.07733177575208161,-0.2619266677946719,-0.350125356105606,-0.32056824010222307,0.673901466516914,0.7953385242734627,1.638208714171853,-0.5003402500028168,-0.4097204049195783,0.7953385242734627,0.4481994586006217,-1.5353706399979128,-0.5308810490428666,-2.7143982394363206,-0.5924746168808616,0.5244829444562599,0.39674143767950243,-0.9440776667177786,0.2923398612170866,0.3447912610633156,1.9567810941536743,-0.2619266677946719,-0.654763070997487,-0.654763070997487,-0.5924746168808616,-0.43976167580769304
2,702
transporter
18
56
2.64912
0.00807
P53985,Q15070,P55735,Q9HD45,Q99595,O15397,O43772,Q7Z3B4,Q9UI26,Q8NFH4,P52292,Q9H2D1,Q12769,P41440,Q8N1F7,Q6N075,Q9NR77,Q567V2
Functions
Panther Protein class
panther_protein_class
192,224,380,265,5,313,10,525,575,212,300,184,280,115,506,58,453,63
1550,2322,1926,2522,1355,313,729,926,10,1360,763,1009,2327,1879,115,2193,1276,300,1423,1227,192,1279,1991,380,705,1680,280,1473,224,63,58,525,506,212,992,1797,912,873,875,841,1034,5,753,640,1749,2136,184,1915,1535,265,453,575,1213,576,1598,1084
-0.2328390217993925,-0.7495318851344548,-0.43976167580769304,-1.0439690553345753,-0.1180065861783075,0.8431585826801586,0.31862879037972053,0.15895673427969537,4.396604319498196,-0.1180065861783075,0.2923398612170866,0.10467597056101892,-0.7495318851344548,-0.4097204049195783,1.7398321727024608,-0.6235310490678561,-0.06148029559266701,0.890558218300318,-0.14649000038336524,-0.03343454335768025,1.3211587294181275,-0.06148029559266701,-0.4699677127277454,0.7228043903765459,0.3447912610633156,-0.2911692129463672,0.9608846498386505,-0.17512221304650355,1.1665076288666967,2.365660090880429,2.436706104734128,0.5244829444562599,0.5496741112974982,1.2333342498208812,0.13188385952514886,-0.350125356105606,0.18589586847145548,0.2127025180887077,0.2127025180887077,0.23937792178355133,0.10467597056101892,5.198120334434664,0.31862879037972053,0.4225314103597223,-0.32056824010222307,-0.5615918989070766,1.3645361307346424,-0.4097204049195783,-0.2039047156366997,1.0303037635203478,0.6245521818790327,0.473746678395286,-0.005531837066441173,0.473746678395286,-0.2328390217993925,0.07733177575208161
2,702
Alternative mrna splicing via spliceosome
19
38
2.625406
0.008655
Q07955,Q9Y2W1,Q9UHX1,Q96MU7,Q9BWF3,P98175,P23246,P17844,Q07666,P38159,Q96T37,Q96I25,Q92879,P51116,P51114,P62995,Q13242,Q8NDT2,Q13247
Processes and pathways
GO Biological process
msigdb_gobp
260,405,553,684,687,416,411,537,678,176,450,449,600,71,203,465,370,245,249
1352,1133,891,1817,537,411,1363,1985,176,825,203,71,1105,1018,673,465,416,1729,678,260,1840,1577,370,249,1474,1327,776,245,1243,600,449,684,450,687,553,405,1970,1707
-0.1180065861783075,0.02222921008355008,0.18589586847145548,-0.37984219227896826,0.49917415125399284,0.673901466516914,-0.1180065861783075,-0.4699677127277454,1.386093528320324,0.23937792178355133,1.255425828169697,2.2572569188414064,0.0498499651371408,0.10467597056101892,0.37082842982646413,0.5997077106006617,0.673901466516914,-0.32056824010222307,0.37082842982646413,1.0303037635203478,-0.37984219227896826,-0.2328390217993925,0.747090864182487,1.0532456836169948,-0.17512221304650355,-0.08967050071108885,0.2923398612170866,1.0760900505966375,-0.03343454335768025,0.4481994586006217,0.6245521818790327,0.37082842982646413,0.6245521818790327,0.37082842982646413,0.49917415125399284,0.698408241052304,-0.43976167580769304,-0.2911692129463672
2,702
Skin nodule
6
20
2.619768
0.008799
Q9NZ08,Q13510,P48735,O75874,Q9NSE4,P06280
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
135,111,17,54,87,149
54,149,2551,702,1717,1776,1367,155,17,2194,826,2399,1839,111,710,507,951,87,135,353
2.558767311500275,1.4925940643576996,-1.1115742979561345,0.3447912610633156,-0.32056824010222307,-0.350125356105606,-0.1180065861783075,1.4714633126430223,4.123983608212495,-0.6235310490678561,0.23937792178355133,-0.8136248100970255,-0.37984219227896826,1.7799433878907398,0.3447912610633156,0.5496741112974982,0.15895673427969537,2.0714733698385936,1.5970092420957023,0.7953385242734627
2,702
Abnormal circulating fatty acid concentration
10
20
2.618774
0.008825
Q16836,P50542,O43772,Q9H845,P11310,O75880,O75431,P09622,P23786,P40855
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
503,379,10,606,141,296,461,620,88,223
10,1456,461,616,296,620,141,1558,88,1465,223,1468,1615,379,1833,1572,1149,503,1153,606
4.396604319498196,-0.17512221304650355,0.5997077106006617,0.4225314103597223,0.890558218300318,0.4225314103597223,1.5554884161976426,-0.2328390217993925,2.0525300254302943,-0.17512221304650355,1.1665076288666967,-0.17512221304650355,-0.2619266677946719,0.7228043903765459,-0.37984219227896826,-0.2328390217993925,0.02222921008355008,0.5496741112974982,0.02222921008355008,0.4481994586006217
2,702
Serine hydrolase activity
6
18
2.618237
0.008839
P42785,P10619,O75976,Q9H3G5,Q16740,Q9HB40
Functions
GO Molecular function
msigdb_gomf
0,163,196,44,25,29
201,196,163,2114,1984,2670,1567,0,2296,1227,769,25,1581,546,2052,332,44,29
1.255425828169697,1.2774266291404368,1.4289490678170462,-0.5615918989070766,-0.4699677127277454,-2.0740082524478405,-0.2328390217993925,6.217718739388483,-0.7177615370892623,-0.03343454335768025,0.2923398612170866,3.502073656744272,-0.2328390217993925,0.49917415125399284,-0.5003402500028168,0.8193015508006276,2.827512784417395,3.341494967883903
2,702
Inner mitochondrial membrane protein complex
26
70
2.602907
0.009244
Q99595,O75964,Q9P0J0,Q9BPX6,O75489,P14406,Q16718,Q9NX63,P00403,P06576,Q99623,O96000,Q9BVV7,Q13505,Q9HAV7,O75431,P56385,Q9Y5J7,Q16891,P13073,O95139,P56134,Q9Y4W6,P22695,P24539,O43676
Localization
GO Cellular component
msigdb_gocc
5,256,532,139,646,22,544,290,35,292,436,172,451,64,607,461,347,493,485,477,474,369,644,122,621,127
2142,1708,852,1764,127,925,1361,730,461,646,1136,256,474,856,1415,1499,1931,172,35,292,666,1876,1268,1098,477,22,1669,1771,649,1717,122,621,896,1272,1719,2364,1317,1015,1466,1370,2331,1017,369,347,64,544,1998,485,1190,867,1118,774,2465,2235,2506,5,436,139,1482,451,607,757,290,532,721,2023,644,1490,493,1971
-0.5924746168808616,-0.32056824010222307,0.2127025180887077,-0.350125356105606,1.638208714171853,0.15895673427969537,-0.1180065861783075,0.31862879037972053,0.5997077106006617,0.39674143767950243,0.02222921008355008,1.0303037635203478,0.5747486913303033,0.2127025180887077,-0.14649000038336524,-0.2039047156366997,-0.43976167580769304,1.386093528320324,3.1141580717849924,0.9141025725456303,0.37082842982646413,-0.4097204049195783,-0.06148029559266701,0.0498499651371408,0.5747486913303033,3.643834047397023,-0.2911692129463672,-0.350125356105606,0.39674143767950243,-0.32056824010222307,1.6586894203500797,0.4225314103597223,0.18589586847145548,-0.06148029559266701,-0.32056824010222307,-0.7814856320202566,-0.08967050071108885,0.10467597056101892,-0.17512221304650355,-0.1180065861783075,-0.7495318851344548,0.10467597056101892,0.747090864182487,0.7953385242734627,2.3477474020211564,0.49917415125399284,-0.4699677127277454,0.5747486913303033,-0.005531837066441173,0.2127025180887077,0.0498499651371408,0.2923398612170866,-0.9111757607706441,-0.654763070997487,-0.977175681919584,5.198120334434664,0.6492831048866388,1.5762892971839588,-0.17512221304650355,0.6245521818790327,0.4481994586006217,0.31862879037972053,0.9375444335085626,0.5244829444562599,0.3447912610633156,-0.4699677127277454,0.4225314103597223,-0.17512221304650355,0.5747486913303033,-0.43976167580769304
2,702
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]
51
121
2.600201
0.009317
P23588,O60506,P84103,P52597,Q07955,Q9UKV3,P31943,P08579,Q9UHX1,P35637,Q9BWF3,P98175,P23246,P07910,P09012,Q9BZI7,Q15056,Q86U42,Q9P2N5,P38159,P31942,P52756,Q14103,P51991,Q96T37,O75494,Q96I25,Q9UKM9,Q92879,O43390,Q9Y6M1,Q01085,O14979,P78332,Q86V81,Q08170,Q9Y2U8,P62995,P22626,P11940,P19338,Q16629,P98179,Q13242,Q9UN86,Q8NDT2,Q96PK6,Q99729,Q13247,Q01844,Q92804
Sequence
InterPro Superfamily
interpro_homologous_superfamily
378,496,500,626,260,533,395,393,553,155,687,416,411,293,408,689,543,305,438,176,298,673,570,566,450,558,449,723,600,314,472,331,330,706,598,593,353,465,345,585,344,633,106,370,517,245,246,247,249,382,250
885,1492,330,1086,963,314,927,496,558,1662,1265,1095,293,393,1606,408,891,585,1817,1715,344,345,411,378,971,1363,1985,298,395,1178,155,176,2392,796,825,566,1018,626,673,799,1783,1619,465,706,500,416,106,331,382,2618,260,593,801,1021,1022,370,802,249,2047,1112,1732,570,1430,1187,904,1024,543,831,1474,709,1234,907,2504,633,1633,1116,980,1950,305,598,947,776,2344,2003,245,1391,1161,2167,911,2004,250,600,914,449,246,450,1339,247,687,783,996,689,997,2349,1000,1403,1251,1863,1211,438,1654,553,1169,723,533,517,353,1082,1005,1707,472
0.18589586847145548,-0.2039047156366997,0.8193015508006276,0.0498499651371408,0.13188385952514886,0.8431585826801586,0.15895673427969537,0.5496741112974982,0.473746678395286,-0.2911692129463672,-0.06148029559266701,0.0498499651371408,0.9141025725456303,0.698408241052304,-0.2619266677946719,0.673901466516914,0.18589586847145548,0.4481994586006217,-0.37984219227896826,-0.32056824010222307,0.7953385242734627,0.7953385242734627,0.673901466516914,0.7228043903765459,0.13188385952514886,-0.1180065861783075,-0.4699677127277454,0.890558218300318,0.698408241052304,-0.005531837066441173,1.4714633126430223,1.386093528320324,-0.8136248100970255,0.2659233011870234,0.23937792178355133,0.473746678395286,0.10467597056101892,0.4225314103597223,0.37082842982646413,0.2659233011870234,-0.350125356105606,-0.2619266677946719,0.5997077106006617,0.3447912610633156,0.5496741112974982,0.673901466516914,1.8395473434978173,0.8193015508006276,0.7228043903765459,-1.3905052682383434,1.0303037635203478,0.4481994586006217,0.2659233011870234,0.10467597056101892,0.10467597056101892,0.747090864182487,0.2659233011870234,1.0532456836169948,-0.5003402500028168,0.0498499651371408,-0.32056824010222307,0.473746678395286,-0.14649000038336524,-0.005531837066441173,0.18589586847145548,0.10467597056101892,0.49917415125399284,0.23937792178355133,-0.17512221304650355,0.3447912610633156,-0.03343454335768025,0.18589586847145548,-0.977175681919584,0.4225314103597223,-0.2619266677946719,0.0498499651371408,0.13188385952514886,-0.43976167580769304,0.890558218300318,0.4481994586006217,0.15895673427969537,0.2923398612170866,-0.7495318851344548,-0.4699677127277454,1.0760900505966375,-0.1180065861783075,0.02222921008355008,-0.5924746168808616,0.18589586847145548,-0.4699677127277454,1.0532456836169948,0.4481994586006217,0.18589586847145548,0.6245521818790327,1.0760900505966375,0.6245521818790327,-0.08967050071108885,1.0760900505966375,0.37082842982646413,0.2923398612170866,0.13188385952514886,0.37082842982646413,0.13188385952514886,-0.7495318851344548,0.13188385952514886,-0.1180065861783075,-0.03343454335768025,-0.37984219227896826,-0.005531837066441173,0.6492831048866388,-0.2619266677946719,0.49917415125399284,0.02222921008355008,0.3447912610633156,0.5244829444562599,0.5496741112974982,0.7953385242734627,0.07733177575208161,0.13188385952514886,-0.2911692129463672,0.5997077106006617
2,702
Neuronal system
13
52
2.597707
0.009385
Q15418,P21964,P53680,P51812,Q9Y2J2,P52292,Q9H2H9,P04350,O95197,P41440,Q9BVA1,P68371,Q13885
Processes and pathways
Reactome Pathways
msigdb_reactome
2,34,318,11,213,300,84,210,214,115,220,124,190
1175,853,2575,965,1307,1555,214,1711,210,2568,375,315,732,2358,1010,892,1097,1011,1012,34,2388,2191,115,2264,1103,1942,11,300,318,798,2203,1726,653,124,2445,190,1733,501,743,1287,2,2308,1852,1440,603,220,84,1542,2411,1704,213,1761
-0.005531837066441173,0.2127025180887077,-1.2145462814230732,0.13188385952514886,-0.08967050071108885,-0.2328390217993925,1.2111511761503668,-0.32056824010222307,1.2333342498208812,-1.1800104648843361,0.7228043903765459,0.8431585826801586,0.31862879037972053,-0.7814856320202566,0.10467597056101892,0.18589586847145548,0.0498499651371408,0.10467597056101892,0.10467597056101892,3.1296283127460667,-0.8136248100970255,-0.6235310490678561,1.7398321727024608,-0.6861725882485472,0.0498499651371408,-0.43976167580769304,4.3359171716292355,0.890558218300318,0.8431585826801586,0.2659233011870234,-0.6235310490678561,-0.32056824010222307,0.39674143767950243,1.6586894203500797,-0.8784677570852006,1.3428914236840213,-0.32056824010222307,0.5496741112974982,0.31862879037972053,-0.06148029559266701,5.468469224387756,-0.7177615370892623,-0.37984219227896826,-0.14649000038336524,0.4481994586006217,1.1888758808001145,2.090348997439926,-0.2039047156366997,-0.8136248100970255,-0.2911692129463672,1.2333342498208812,-0.32056824010222307
2,702
Late endosome
10
52
2.577737
0.009945
Q99538,Q8IV08,Q8TCT8,P11279,Q14108,Q9BUN8,O15118,Q9Y4G8,P07602,P11717
Localization
GO Cellular component
msigdb_gocc
99,4,144,236,19,215,24,254,57,120
2221,1411,24,1357,1976,815,560,57,820,1010,892,236,120,1935,268,2388,2191,1566,1569,1422,1724,368,1425,1683,482,19,2097,1999,4,806,807,144,1122,2628,956,1643,99,2492,754,215,782,1648,2379,1751,880,1252,2217,1254,2022,1004,2072,254
-0.654763070997487,-0.14649000038336524,3.530739879481159,-0.1180065861783075,-0.4699677127277454,0.23937792178355133,0.473746678395286,2.436706104734128,0.23937792178355133,0.10467597056101892,0.18589586847145548,1.0988376535312658,1.6994156728204817,-0.43976167580769304,1.0072634916981495,-0.8136248100970255,-0.6235310490678561,-0.2328390217993925,-0.2328390217993925,-0.14649000038336524,-0.32056824010222307,0.747090864182487,-0.14649000038336524,-0.2911692129463672,0.5747486913303033,4.111237733873485,-0.5308810490428666,-0.4699677127277454,5.2288928568634425,0.2659233011870234,0.2659233011870234,1.5346059932631821,0.0498499651371408,-1.4263717244472445,0.15895673427969537,-0.2619266677946719,1.8789142803170127,-0.9440776667177786,0.31862879037972053,1.2111511761503668,0.2923398612170866,-0.2619266677946719,-0.7814856320202566,-0.32056824010222307,0.2127025180887077,-0.03343454335768025,-0.6235310490678561,-0.03343454335768025,-0.4699677127277454,0.13188385952514886,-0.5003402500028168,1.0532456836169948
2,702
Lipid catabolic process
15
67
2.57555
0.010008
Q8NCC3,Q8WTV0,P17900,O15254,P11310,Q13510,Q13011,Q8N2K0,Q8NHP8,Q9H6V9,P50897,O75874,P23786,P06280,Q9BWD1
Processes and pathways
GO Biological process
msigdb_gobp
134,69,70,72,141,111,48,113,147,51,52,54,88,149,94
1658,2695,72,1131,1008,54,2291,648,443,582,2693,1604,149,168,1096,2079,141,2551,1223,1558,70,1312,860,88,1504,934,1463,1877,1313,1776,1986,233,1468,1101,2039,2518,1615,379,52,1422,1833,1572,901,1149,48,111,274,1631,908,1740,503,2053,2001,2131,2626,113,1068,134,147,69,1746,1644,1801,94,51,2171,1651
-0.2911692129463672,-4.8821959377233615,2.2389705497371217,0.02222921008355008,0.10467597056101892,2.558767311500275,-0.7177615370892623,0.39674143767950243,0.6245521818790327,0.4481994586006217,-4.501064891738855,-0.2619266677946719,1.4925940643576996,1.4075642865122227,0.0498499651371408,-0.5308810490428666,1.5554884161976426,-1.1115742979561345,-0.03343454335768025,-0.2328390217993925,2.2572569188414064,-0.08967050071108885,0.2127025180887077,2.0525300254302943,-0.2039047156366997,0.15895673427969537,-0.17512221304650355,-0.4097204049195783,-0.08967050071108885,-0.350125356105606,-0.4699677127277454,1.1214892721063172,-0.17512221304650355,0.0498499651371408,-0.5003402500028168,-1.0104720506565676,-0.2619266677946719,0.7228043903765459,2.678047917700652,-0.14649000038336524,-0.37984219227896826,-0.2328390217993925,0.18589586847145548,0.02222921008355008,2.745005746127423,1.7799433878907398,0.9841240598522195,-0.2619266677946719,0.18589586847145548,-0.32056824010222307,0.5496741112974982,-0.5003402500028168,-0.4699677127277454,-0.5615918989070766,-1.4263717244472445,1.7599256653622593,0.07733177575208161,1.5970092420957023,1.5136414157872253,2.275479978158442,-0.32056824010222307,-0.2619266677946719,-0.350125356105606,1.9567810941536743,2.7283466065358986,-0.5924746168808616,-0.2619266677946719
2,702
Receptor
8
25
2.564595
0.01033
Q9UQB8,Q13432,Q8WTV0,A6NIH7,Q14108,Q9BUN8,P11717,Q567V2
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
32,161,69,101,19,215,120,63
101,1355,1978,1456,1555,1711,619,120,268,1509,482,161,446,19,63,2052,69,1195,215,1535,453,2594,2633,32,1761
1.8592673659235324,-0.1180065861783075,-0.4699677127277454,-0.17512221304650355,-0.2328390217993925,-0.32056824010222307,0.4225314103597223,1.6994156728204817,1.0072634916981495,-0.2039047156366997,0.5747486913303033,1.4502485272895491,0.6245521818790327,4.111237733873485,2.365660090880429,-0.5003402500028168,2.275479978158442,-0.005531837066441173,1.2111511761503668,-0.2039047156366997,0.6245521818790327,-1.2492972789568666,-1.4988015177811698,3.281841750088034,-0.32056824010222307
2,702
Increased susceptibility to fractures
10
43
2.562478
0.010393
Q32P28,O60568,P48735,P06753,Q14108,Q9Y2U8,O75874,Q8WWQ0,P22626,Q13126
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
68,136,17,297,19,353,54,119,345,62
2143,727,2074,136,1814,518,54,2477,1265,443,1266,857,297,858,891,1010,1051,1012,345,2035,1564,1367,2460,17,2042,1882,2399,1149,1886,62,829,19,359,68,635,119,509,686,1344,1700,918,1652,353
-0.5924746168808616,0.31862879037972053,-0.5308810490428666,1.5762892971839588,-0.37984219227896826,0.5244829444562599,2.558767311500275,-0.9440776667177786,-0.06148029559266701,0.6245521818790327,-0.06148029559266701,0.2127025180887077,0.890558218300318,0.2127025180887077,0.18589586847145548,0.10467597056101892,0.07733177575208161,0.10467597056101892,0.7953385242734627,-0.5003402500028168,-0.2328390217993925,-0.1180065861783075,-0.9111757607706441,4.123983608212495,-0.5003402500028168,-0.4097204049195783,-0.8136248100970255,0.02222921008355008,-0.4097204049195783,2.365660090880429,0.23937792178355133,4.111237733873485,0.7712686001756313,2.293640144931326,0.4225314103597223,1.7196623603455143,0.5496741112974982,0.37082842982646413,-0.08967050071108885,-0.2911692129463672,0.18589586847145548,-0.2619266677946719,0.7953385242734627
2,702
serine protease
6
17
2.557033
0.010557
P42785,P10619,Q9H3G5,Q8N2K0,Q16740,Q9HB40
Functions
Panther Protein class
panther_protein_class
0,163,44,113,25,29
201,163,2146,2114,1984,2670,1567,0,2296,769,25,1581,332,113,44,29,2064
1.255425828169697,1.4289490678170462,-0.5924746168808616,-0.5615918989070766,-0.4699677127277454,-2.0740082524478405,-0.2328390217993925,6.217718739388483,-0.7177615370892623,0.2923398612170866,3.502073656744272,-0.2328390217993925,0.8193015508006276,1.7599256653622593,2.827512784417395,3.341494967883903,-0.5003402500028168
2,702
Subcutaneous nodule
6
18
2.556722
0.010566
Q9NZ08,Q13510,P48735,O75874,Q9NSE4,P06280
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
135,111,17,54,87,149
54,149,2551,1717,1776,1367,155,17,2194,826,2399,1839,111,710,507,87,135,353
2.558767311500275,1.4925940643576996,-1.1115742979561345,-0.32056824010222307,-0.350125356105606,-0.1180065861783075,1.4714633126430223,4.123983608212495,-0.6235310490678561,0.23937792178355133,-0.8136248100970255,-0.37984219227896826,1.7799433878907398,0.3447912610633156,0.5496741112974982,2.0714733698385936,1.5970092420957023,0.7953385242734627
2,702
Selective autophagy
8
28
2.550667
0.010752
Q9NS69,P08670,Q8N4H5,P04350,Q15388,P68371,Q13885,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
6,202,138,210,86,124,190,31
1976,615,966,699,210,1768,202,892,587,31,379,798,1882,768,2580,124,2048,190,1947,86,682,138,572,2593,603,220,6,1216
-0.4699677127277454,0.4225314103597223,0.13188385952514886,0.3447912610633156,1.2333342498208812,-0.350125356105606,1.255425828169697,0.18589586847145548,0.4481994586006217,3.281841750088034,0.7228043903765459,0.2659233011870234,-0.4097204049195783,0.2923398612170866,-1.2145462814230732,1.6586894203500797,-0.5003402500028168,1.3428914236840213,-0.43976167580769304,2.0714733698385936,0.37082842982646413,1.5762892971839588,0.473746678395286,-1.2492972789568666,0.4481994586006217,1.1888758808001145,4.890473754334426,-0.005531837066441173
2,702
Activation of nmda receptors and postsynaptic events
7
23
2.54904
0.010802
Q15418,P51812,P52292,P04350,Q9BVA1,P68371,Q13885
Processes and pathways
Reactome Pathways
msigdb_reactome
2,11,300,210,220,124,190
1175,210,315,1010,1011,1012,2388,2191,1103,11,300,798,2203,124,2445,190,1733,501,1287,2,2308,603,220
-0.005531837066441173,1.2333342498208812,0.8431585826801586,0.10467597056101892,0.10467597056101892,0.10467597056101892,-0.8136248100970255,-0.6235310490678561,0.0498499651371408,4.3359171716292355,0.890558218300318,0.2659233011870234,-0.6235310490678561,1.6586894203500797,-0.8784677570852006,1.3428914236840213,-0.32056824010222307,0.5496741112974982,-0.06148029559266701,5.468469224387756,-0.7177615370892623,0.4481994586006217,1.1888758808001145
2,702
Glycerophospholipid biosynthesis
6
27
2.547117
0.010862
Q9NPH0,Q6P1A2,Q8IV08,Q8NCC3,P43304,Q9NQZ5
Processes and pathways
Reactome Pathways
msigdb_reactome
1,164,4,134,42,60
555,1450,1496,341,587,237,1468,42,2500,2193,1572,2580,867,164,773,4,1794,134,637,1070,2210,2507,2104,1,60,787,1297
0.473746678395286,-0.17512221304650355,-0.2039047156366997,0.7953385242734627,0.4481994586006217,1.0988376535312658,-0.17512221304650355,2.827512784417395,-0.977175681919584,-0.6235310490678561,-0.2328390217993925,-1.2145462814230732,0.2127025180887077,1.4289490678170462,0.2923398612170866,5.2288928568634425,-0.350125356105606,1.5970092420957023,0.4225314103597223,0.07733177575208161,-0.6235310490678561,-0.977175681919584,-0.5308810490428666,6.184106568144779,2.3835119137294205,0.2923398612170866,-0.06148029559266701
2,702
Protein targeting to mitochondrion
14
39
2.546294
0.010887
Q9BVV7,P30536,Q99595,Q9NS69,O95831,Q9P0J0,Q8N4H5,Q99496,Q9HAV7,Q15388,O14737,P55786,Q9Y5J7,Q5JRX3
Processes and pathways
GO Biological process
msigdb_gobp
451,412,5,6,39,532,138,335,607,86,217,92,493,546
1351,217,852,729,2324,966,2525,39,699,1768,765,587,412,2084,1941,1832,92,1375,1110,86,1190,867,546,2343,138,1743,335,5,780,451,1204,607,6,532,1653,2071,1490,493,884
-0.1180065861783075,1.1888758808001145,0.2127025180887077,0.31862879037972053,-0.7495318851344548,0.13188385952514886,-1.0439690553345753,2.9408710467958437,0.3447912610633156,-0.350125356105606,0.2923398612170866,0.4481994586006217,0.673901466516914,-0.5308810490428666,-0.43976167580769304,-0.37984219227896826,2.0144383197469633,-0.1180065861783075,0.0498499651371408,2.0714733698385936,-0.005531837066441173,0.2127025180887077,0.49917415125399284,-0.7495318851344548,1.5762892971839588,-0.32056824010222307,0.8193015508006276,5.198120334434664,0.2923398612170866,0.6245521818790327,-0.005531837066441173,0.4481994586006217,4.890473754334426,0.5244829444562599,-0.2619266677946719,-0.5003402500028168,-0.17512221304650355,0.5747486913303033,0.2127025180887077
2,702
Calmodulin
6
11
2.543941
0.010961
Q9BPX6,Q15293,O43852,Q14257,P80303,Q02818
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
139,82,179,116,118,244
179,623,1373,397,118,244,116,82,1290,990,139
1.3645361307346424,0.4225314103597223,-0.1180065861783075,0.698408241052304,1.7196623603455143,1.0760900505966375,1.7398321727024608,2.183727349455117,-0.06148029559266701,0.13188385952514886,1.5762892971839588
2,702
Intracellular calcium-sensing protein
6
11
2.543941
0.010961
Q9BPX6,Q15293,O43852,Q14257,P80303,Q02818
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
139,82,179,116,118,244
179,623,1373,397,118,244,116,82,1290,990,139
1.3645361307346424,0.4225314103597223,-0.1180065861783075,0.698408241052304,1.7196623603455143,1.0760900505966375,1.7398321727024608,2.183727349455117,-0.06148029559266701,0.13188385952514886,1.5762892971839588
2,702
Negative regulation of mrna metabolic process
19
43
2.540448
0.011071
O60506,Q9Y2W1,Q5VTR2,P35637,P98175,P67809,P07910,P38159,P61978,Q14103,O75494,P50750,Q08170,P22626,P11940,Q13242,Q99729,Q13247,Q92804
Processes and pathways
GO Biological process
msigdb_gobp
496,405,523,155,416,415,293,176,301,570,558,564,593,345,585,370,247,249,250
1866,1352,496,1089,558,1134,293,585,2480,1715,345,971,1363,155,176,564,301,415,416,1729,974,593,1840,1577,1021,1022,370,249,570,1474,907,1434,633,523,1331,1193,1384,2004,250,247,1205,1863,405
-0.4097204049195783,-0.1180065861783075,0.5496741112974982,0.0498499651371408,0.473746678395286,0.02222921008355008,0.9141025725456303,0.4481994586006217,-0.9440776667177786,-0.32056824010222307,0.7953385242734627,0.13188385952514886,-0.1180065861783075,1.4714633126430223,1.386093528320324,0.473746678395286,0.890558218300318,0.673901466516914,0.673901466516914,-0.32056824010222307,0.13188385952514886,0.4481994586006217,-0.37984219227896826,-0.2328390217993925,0.10467597056101892,0.10467597056101892,0.747090864182487,1.0532456836169948,0.473746678395286,-0.17512221304650355,0.18589586847145548,-0.14649000038336524,0.4225314103597223,0.5244829444562599,-0.08967050071108885,-0.005531837066441173,-0.1180065861783075,-0.4699677127277454,1.0532456836169948,1.0760900505966375,-0.005531837066441173,-0.37984219227896826,0.698408241052304
2,702
Abnormal retinal artery morphology
6
20
2.532238
0.011334
P16278,P21964,P10619,P17900,Q13510,P07602
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,34,163,70,111,57
536,2648,168,57,1096,163,1714,128,70,34,1937,1834,1624,111,543,2236,872,880,661,1864
0.49917415125399284,-1.6840786597335329,1.4075642865122227,2.436706104734128,0.0498499651371408,1.4289490678170462,-0.32056824010222307,1.638208714171853,2.2572569188414064,3.1296283127460667,-0.43976167580769304,-0.37984219227896826,-0.2619266677946719,1.7799433878907398,0.49917415125399284,-0.654763070997487,0.2127025180887077,0.2127025180887077,0.39674143767950243,-0.37984219227896826
2,702
Ion transmembrane transporter activity
22
98
2.515986
0.01187
O75964,O43772,O15439,P45880,P21796,P00403,Q9C0H2,P06576,Q13423,Q70HW3,Q9H2D1,Q6N075,Q9Y277,P53985,Q9Y487,Q6P4A7,Q9H2H9,P56385,P51790,P56134,P41440,Q9HD20
Functions
GO Molecular function
msigdb_gomf
256,10,267,23,31,35,165,292,177,49,184,58,329,192,78,75,84,347,368,369,115,252
1867,614,267,926,10,1131,889,1136,256,818,2658,35,764,968,1462,1048,292,560,820,969,666,1268,2669,1980,1098,477,702,1503,649,823,1772,31,1417,621,896,2364,2688,1015,898,1780,115,23,1370,2394,368,2042,192,369,347,414,1680,2127,1786,1471,177,1062,1686,1288,58,713,2053,75,49,504,836,2235,1030,528,1586,2467,529,2665,1956,511,1440,639,640,781,1342,165,1038,184,84,1294,608,252,516,721,1348,812,2176,329,1215,78,388,1084,2616,789
-0.4097204049195783,0.4225314103597223,1.0072634916981495,0.15895673427969537,4.396604319498196,0.02222921008355008,0.18589586847145548,0.02222921008355008,1.0303037635203478,0.23937792178355133,-1.8368287909913394,3.1141580717849924,0.2923398612170866,0.13188385952514886,-0.17512221304650355,0.07733177575208161,0.9141025725456303,0.473746678395286,0.23937792178355133,0.13188385952514886,0.37082842982646413,-0.06148029559266701,-2.0740082524478405,-0.4699677127277454,0.0498499651371408,0.5747486913303033,0.3447912610633156,-0.2039047156366997,0.39674143767950243,0.23937792178355133,-0.350125356105606,3.281841750088034,-0.14649000038336524,0.4225314103597223,0.18589586847145548,-0.7814856320202566,-3.1850832781614544,0.10467597056101892,0.18589586847145548,-0.350125356105606,1.7398321727024608,3.587597806701549,-0.1180065861783075,-0.8136248100970255,0.747090864182487,-0.5003402500028168,1.3211587294181275,0.747090864182487,0.7953385242734627,0.673901466516914,-0.2911692129463672,-0.5615918989070766,-0.350125356105606,-0.17512221304650355,1.386093528320324,0.07733177575208161,-0.2911692129463672,-0.06148029559266701,2.436706104734128,0.3447912610633156,-0.5003402500028168,2.2206204495029636,2.745005746127423,0.5496741112974982,0.23937792178355133,-0.654763070997487,0.10467597056101892,0.5244829444562599,-0.2328390217993925,-0.9111757607706441,0.5244829444562599,-1.9147862223575949,-0.43976167580769304,0.5496741112974982,-0.14649000038336524,0.4225314103597223,0.4225314103597223,0.2923398612170866,-0.08967050071108885,1.4289490678170462,0.10467597056101892,1.3645361307346424,2.090348997439926,-0.06148029559266701,0.4481994586006217,1.0532456836169948,0.5496741112974982,0.3447912610633156,-0.08967050071108885,0.2659233011870234,-0.5924746168808616,0.8431585826801586,-0.005531837066441173,2.2206204495029636,0.7228043903765459,0.07733177575208161,-1.3548673355819485,0.2923398612170866
2,702
Cellular lipid catabolic process
14
60
2.51168
0.012016
Q8NCC3,Q8WTV0,P17900,O15254,P11310,Q13510,Q13011,Q8N2K0,Q8NHP8,P50897,O75874,P23786,P06280,Q9BWD1
Processes and pathways
GO Biological process
msigdb_gobp
134,69,70,72,141,111,48,113,147,52,54,88,149,94
1658,2695,72,1131,1008,54,2291,648,443,582,2693,1604,149,168,1096,2079,141,1223,1558,70,1312,860,88,1504,934,1463,1877,1313,1776,1986,1468,1101,2039,1615,379,52,1833,1572,1149,48,111,274,908,1740,503,2053,2001,2131,2626,113,1068,134,147,69,1746,1644,1801,94,2171,1651
-0.2911692129463672,-4.8821959377233615,2.2389705497371217,0.02222921008355008,0.10467597056101892,2.558767311500275,-0.7177615370892623,0.39674143767950243,0.6245521818790327,0.4481994586006217,-4.501064891738855,-0.2619266677946719,1.4925940643576996,1.4075642865122227,0.0498499651371408,-0.5308810490428666,1.5554884161976426,-0.03343454335768025,-0.2328390217993925,2.2572569188414064,-0.08967050071108885,0.2127025180887077,2.0525300254302943,-0.2039047156366997,0.15895673427969537,-0.17512221304650355,-0.4097204049195783,-0.08967050071108885,-0.350125356105606,-0.4699677127277454,-0.17512221304650355,0.0498499651371408,-0.5003402500028168,-0.2619266677946719,0.7228043903765459,2.678047917700652,-0.37984219227896826,-0.2328390217993925,0.02222921008355008,2.745005746127423,1.7799433878907398,0.9841240598522195,0.18589586847145548,-0.32056824010222307,0.5496741112974982,-0.5003402500028168,-0.4699677127277454,-0.5615918989070766,-1.4263717244472445,1.7599256653622593,0.07733177575208161,1.5970092420957023,1.5136414157872253,2.275479978158442,-0.32056824010222307,-0.2619266677946719,-0.350125356105606,1.9567810941536743,-0.5924746168808616,-0.2619266677946719
2,702
Hydrolase activity hydrolyzing o glycosyl compounds
7
18
2.502232
0.012341
P16278,P54802,P17900,Q16706,P06865,O60502,P06280
Functions
GO Molecular function
msigdb_gomf
128,98,70,132,168,46,149
2475,46,443,582,149,168,1096,701,463,128,70,2529,98,829,1735,132,230,847
-0.9440776667177786,2.7781653386568346,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,0.0498499651371408,0.3447912610633156,0.5997077106006617,1.638208714171853,2.2572569188414064,-1.0439690553345753,1.8789142803170127,0.23937792178355133,-0.32056824010222307,1.5970092420957023,1.1440456767678313,0.23937792178355133
2,702
Hepatic failure
17
40
2.500664
0.012396
Q16836,P04062,P50542,P38571,O43772,Q9H845,Q13043,Q13510,P22830,P16930,O75648,P09622,O15118,O15460,Q9UDY2,P23786,P40855
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
503,443,379,233,10,606,655,111,81,364,616,620,24,89,552,88,223
24,89,10,1814,1456,616,1265,443,857,666,620,364,81,88,1463,1823,233,223,1468,2391,1369,379,1572,1059,1110,655,111,1740,503,982,1634,1901,842,606,918,1595,552,2651,1598,1084
3.530739879481159,2.0335184987881214,4.396604319498196,-0.37984219227896826,-0.17512221304650355,0.4225314103597223,-0.06148029559266701,0.6245521818790327,0.2127025180887077,0.37082842982646413,0.4225314103597223,0.747090864182487,2.183727349455117,2.0525300254302943,-0.17512221304650355,-0.37984219227896826,1.1214892721063172,1.1665076288666967,-0.17512221304650355,-0.8136248100970255,-0.1180065861783075,0.7228043903765459,-0.2328390217993925,0.07733177575208161,0.0498499651371408,0.39674143767950243,1.7799433878907398,-0.32056824010222307,0.5496741112974982,0.13188385952514886,-0.2619266677946719,-0.4097204049195783,0.23937792178355133,0.4481994586006217,0.18589586847145548,-0.2328390217993925,0.49917415125399284,-1.6840786597335329,-0.2328390217993925,0.07733177575208161
2,702
Peroxisome
6
29
2.491055
0.012736
Q9BY49,O15254,Q13011,P48735,O75874,P40855
Processes and pathways
KEGG Pathways
msigdb_kegg
129,72,48,17,54,223
923,1450,72,1131,1601,1456,1008,54,819,792,2079,860,1463,2295,1366,1465,223,17,379,1833,1149,48,274,2050,1744,2102,129,453,2241
0.15895673427969537,-0.17512221304650355,2.2389705497371217,0.02222921008355008,-0.2619266677946719,-0.17512221304650355,0.10467597056101892,2.558767311500275,0.23937792178355133,0.2659233011870234,-0.5308810490428666,0.2127025180887077,-0.17512221304650355,-0.7177615370892623,-0.1180065861783075,-0.17512221304650355,1.1665076288666967,4.123983608212495,0.7228043903765459,-0.37984219227896826,0.02222921008355008,2.745005746127423,0.9841240598522195,-0.5003402500028168,-0.32056824010222307,-0.5308810490428666,1.638208714171853,0.6245521818790327,-0.654763070997487
2,702
Arthritis
16
35
2.477978
0.013213
O15460,P10321,P28070,P02545,P21964,Q9NZ08,P04062,Q14739,Q8NBM4,O75844,Q13510,Q14108,Q96HY6,Q9Y2U8,P06280,P14174
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
89,376,159,374,34,135,443,359,507,74,111,19,276,353,149,218
1351,89,74,2077,374,443,149,2513,376,2564,218,34,2415,159,2194,1057,2042,2368,1834,1677,1680,2399,111,19,359,1061,505,635,507,2236,872,276,135,353,813
-0.1180065861783075,2.0335184987881214,2.2206204495029636,-0.5308810490428666,0.7228043903765459,0.6245521818790327,1.4925940643576996,-1.0104720506565676,0.7228043903765459,-1.1456872992127736,1.1888758808001145,3.1296283127460667,-0.8459514851409792,1.4502485272895491,-0.6235310490678561,0.07733177575208161,-0.5003402500028168,-0.7814856320202566,-0.37984219227896826,-0.2911692129463672,-0.2911692129463672,-0.8136248100970255,1.7799433878907398,4.111237733873485,0.7712686001756313,0.07733177575208161,0.5496741112974982,0.4225314103597223,0.5496741112974982,-0.654763070997487,0.2127025180887077,0.9841240598522195,1.5970092420957023,0.7953385242734627,0.2659233011870234
2,702
Dysphagia
22
113
2.47299
0.013399
Q9Y263,P61916,Q99720,P48735,Q15067,Q14108,O15118,P35637,Q86U42,Q8IZA0,P06753,P15586,O75874,P07602,Q99496,Q8N0X7,P29372,P04350,Q14739,Q01105,Q6Y7W6,Q13510
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
140,142,14,17,274,19,24,155,305,178,297,174,54,57,335,333,346,210,359,238,110,111
790,1974,1353,24,1600,363,2144,730,646,54,664,1092,2634,1415,1264,2077,443,210,297,57,1177,2251,1934,1979,1980,174,1770,499,1716,1717,2083,1272,346,1719,155,1566,1879,1140,1469,1569,796,17,2394,2086,2198,2088,1882,1677,1836,142,2301,2580,827,741,1994,238,417,1838,1787,2630,1148,482,1886,1021,111,19,944,1947,1891,1324,359,274,977,831,1998,869,1478,110,305,178,333,1120,949,1198,1746,1072,956,1339,335,1911,1644,14,844,686,2520,603,1204,1805,1487,453,880,1652,1041,788,1756,1757,553,2495,724,140,1545,2070,644
0.2659233011870234,-0.4699677127277454,-0.1180065861783075,3.530739879481159,-0.2619266677946719,0.747090864182487,-0.5924746168808616,0.31862879037972053,0.39674143767950243,2.558767311500275,0.37082842982646413,0.0498499651371408,-1.5353706399979128,-0.14649000038336524,-0.06148029559266701,-0.5308810490428666,0.6245521818790327,1.2333342498208812,0.890558218300318,2.436706104734128,-0.005531837066441173,-0.6861725882485472,-0.43976167580769304,-0.4699677127277454,-0.4699677127277454,1.386093528320324,-0.350125356105606,0.5496741112974982,-0.32056824010222307,-0.32056824010222307,-0.5308810490428666,-0.06148029559266701,0.7953385242734627,-0.32056824010222307,1.4714633126430223,-0.2328390217993925,-0.4097204049195783,0.02222921008355008,-0.17512221304650355,-0.2328390217993925,0.2659233011870234,4.123983608212495,-0.8136248100970255,-0.5308810490428666,-0.6235310490678561,-0.5308810490428666,-0.4097204049195783,-0.2911692129463672,-0.37984219227896826,1.5554884161976426,-0.7177615370892623,-1.2145462814230732,0.23937792178355133,0.31862879037972053,-0.4699677127277454,1.0988376535312658,0.673901466516914,-0.37984219227896826,-0.350125356105606,-1.4624695189023518,0.02222921008355008,0.5747486913303033,-0.4097204049195783,0.10467597056101892,1.7799433878907398,4.111237733873485,0.15895673427969537,-0.43976167580769304,-0.4097204049195783,-0.08967050071108885,0.7712686001756313,0.9841240598522195,0.13188385952514886,0.23937792178355133,-0.4699677127277454,0.2127025180887077,-0.17512221304650355,1.7998858840313976,0.890558218300318,1.386093528320324,0.8193015508006276,0.0498499651371408,0.15895673427969537,-0.005531837066441173,-0.32056824010222307,0.07733177575208161,0.15895673427969537,-0.08967050071108885,0.8193015508006276,-0.4097204049195783,-0.2619266677946719,4.199796153109882,0.23937792178355133,0.37082842982646413,-1.0104720506565676,0.4481994586006217,-0.005531837066441173,-0.350125356105606,-0.17512221304650355,0.6245521818790327,0.2127025180887077,-0.2619266677946719,0.10467597056101892,0.2923398612170866,-0.32056824010222307,-0.32056824010222307,0.49917415125399284,-0.9440776667177786,0.3447912610633156,1.5762892971839588,-0.2039047156366997,-0.5003402500028168,0.4225314103597223
2,702
Intra golgi and retrograde golgi to er traffic
18
78
2.472186
0.013429
Q13561,Q9H0H5,Q16706,O95721,Q8N2H4,Q02241,P20645,Q13190,O00461,P04350,P24390,O95249,O75935,P11717,Q9BVA1,O15260,P68371,Q13885
Processes and pathways
Reactome Pathways
msigdb_reactome
261,102,132,104,199,258,268,269,266,210,21,279,180,120,220,59,124,190
1865,266,535,59,2184,1976,1928,615,2225,180,1176,1093,279,104,210,120,2326,268,21,1673,2037,1420,2518,2264,2589,1141,1723,1421,1724,826,1725,2044,2368,1944,1679,2200,1228,124,258,1109,828,862,1886,1996,269,2048,261,190,944,1947,1061,1631,596,132,1383,982,987,1158,199,2447,1121,777,1910,550,603,220,531,2060,102,1701,2583,310,882,2472,1128,613,726,1216
-0.4097204049195783,1.0072634916981495,0.49917415125399284,2.419034532533944,-0.6235310490678561,-0.4699677127277454,-0.43976167580769304,0.4225314103597223,-0.654763070997487,1.3645361307346424,-0.005531837066441173,0.0498499651371408,0.9608846498386505,1.8395473434978173,1.2333342498208812,1.6994156728204817,-0.7495318851344548,1.0072634916981495,3.6717230671513654,-0.2911692129463672,-0.5003402500028168,-0.14649000038336524,-1.0104720506565676,-0.6861725882485472,-1.2492972789568666,0.02222921008355008,-0.32056824010222307,-0.14649000038336524,-0.32056824010222307,0.23937792178355133,-0.32056824010222307,-0.5003402500028168,-0.7814856320202566,-0.43976167580769304,-0.2911692129463672,-0.6235310490678561,-0.03343454335768025,1.6586894203500797,1.0303037635203478,0.0498499651371408,0.23937792178355133,0.2127025180887077,-0.4097204049195783,-0.4699677127277454,1.0072634916981495,-0.5003402500028168,1.0303037635203478,1.3428914236840213,0.15895673427969537,-0.43976167580769304,0.07733177575208161,-0.2619266677946719,0.4481994586006217,1.5970092420957023,-0.1180065861783075,0.13188385952514886,0.13188385952514886,0.02222921008355008,1.2774266291404368,-0.8784677570852006,0.0498499651371408,0.2923398612170866,-0.4097204049195783,0.49917415125399284,0.4481994586006217,1.1888758808001145,0.5244829444562599,-0.5003402500028168,1.8592673659235324,-0.2911692129463672,-1.2145462814230732,0.8669105116207638,0.2127025180887077,-0.9111757607706441,0.0498499651371408,0.4481994586006217,0.3447912610633156,-0.005531837066441173
2,702
Outer mitochondrial membrane protein complex
6
16
2.462105
0.013812
Q13505,Q9NX63,Q9NS69,Q8N4H5,O75431,Q15388
Localization
GO Cellular component
msigdb_gocc
64,290,6,138,461,86
461,966,699,1466,64,86,485,1118,774,682,138,1482,6,757,290,1490
0.5997077106006617,0.13188385952514886,0.3447912610633156,-0.17512221304650355,2.3477474020211564,2.0714733698385936,0.5747486913303033,0.0498499651371408,0.2923398612170866,0.37082842982646413,1.5762892971839588,-0.17512221304650355,4.890473754334426,0.31862879037972053,0.9375444335085626,-0.17512221304650355
2,702
Intrinsic component of plasma membrane
22
76
2.442703
0.014578
Q9BTU6,O00560,P10321,O00264,P20645,Q8NB49,O15118,Q9UIQ6,P53985,Q8WTV0,O43657,Q9H2H9,P02786,P51790,Q8N2K0,P11279,O14786,P41440,O96005,P11717,Q9Y4G8,Q9NR28
Localization
GO Cellular component
msigdb_gocc
264,130,376,255,268,146,24,45,192,69,79,84,343,368,113,236,242,115,243,120,254,253
389,255,614,130,242,663,24,2184,79,1304,441,2032,2382,243,343,2414,968,1462,1048,619,376,2358,2669,236,120,1980,702,1270,1502,1503,268,1417,1718,2688,1317,766,936,115,2394,1832,368,192,1943,2566,1786,1471,902,1516,975,446,2591,2271,1287,1686,833,2207,113,146,1796,1586,69,548,1440,780,753,640,264,1038,84,253,45,812,1004,1215,254,1761
0.698408241052304,1.0303037635203478,0.4225314103597223,1.6176488501837785,1.0760900505966375,0.37082842982646413,3.530739879481159,-0.6235310490678561,2.202206192643275,-0.08967050071108885,0.6245521818790327,-0.5003402500028168,-0.8136248100970255,1.0760900505966375,0.7953385242734627,-0.8459514851409792,0.13188385952514886,-0.17512221304650355,0.07733177575208161,0.4225314103597223,0.7228043903765459,-0.7814856320202566,-2.0740082524478405,1.0988376535312658,1.6994156728204817,-0.4699677127277454,0.3447912610633156,-0.06148029559266701,-0.2039047156366997,-0.2039047156366997,1.0072634916981495,-0.14649000038336524,-0.32056824010222307,-3.1850832781614544,-0.08967050071108885,0.2923398612170866,0.15895673427969537,1.7398321727024608,-0.8136248100970255,-0.37984219227896826,0.747090864182487,1.3211587294181275,-0.43976167580769304,-1.1456872992127736,-0.350125356105606,-0.17512221304650355,0.18589586847145548,-0.2039047156366997,0.13188385952514886,0.6245521818790327,-1.2492972789568666,-0.6861725882485472,-0.06148029559266701,-0.2911692129463672,0.23937792178355133,-0.6235310490678561,1.7599256653622593,1.5136414157872253,-0.350125356105606,-0.2328390217993925,2.275479978158442,0.49917415125399284,-0.14649000038336524,0.2923398612170866,0.31862879037972053,0.4225314103597223,1.0303037635203478,0.10467597056101892,2.090348997439926,1.0532456836169948,2.827512784417395,0.2659233011870234,0.13188385952514886,-0.005531837066441173,1.0532456836169948,-0.32056824010222307
2,702
Transmission across chemical synapses
10
43
2.437854
0.014775
Q15418,P21964,P53680,P51812,P52292,Q9H2H9,P04350,Q9BVA1,P68371,Q13885
Processes and pathways
Reactome Pathways
msigdb_reactome
2,34,318,11,300,84,210,220,124,190
1175,2575,1307,1555,1711,210,2568,375,315,732,1010,892,1011,1012,34,2388,2191,2264,1103,1942,11,300,318,798,2203,1726,653,124,2445,190,1733,501,1287,2,2308,1852,1440,603,220,84,1542,1704,1761
-0.005531837066441173,-1.2145462814230732,-0.08967050071108885,-0.2328390217993925,-0.32056824010222307,1.2333342498208812,-1.1800104648843361,0.7228043903765459,0.8431585826801586,0.31862879037972053,0.10467597056101892,0.18589586847145548,0.10467597056101892,0.10467597056101892,3.1296283127460667,-0.8136248100970255,-0.6235310490678561,-0.6861725882485472,0.0498499651371408,-0.43976167580769304,4.3359171716292355,0.890558218300318,0.8431585826801586,0.2659233011870234,-0.6235310490678561,-0.32056824010222307,0.39674143767950243,1.6586894203500797,-0.8784677570852006,1.3428914236840213,-0.32056824010222307,0.5496741112974982,-0.06148029559266701,5.468469224387756,-0.7177615370892623,-0.37984219227896826,-0.14649000038336524,0.4481994586006217,1.1888758808001145,2.090348997439926,-0.2039047156366997,-0.2911692129463672,-0.32056824010222307
2,702
Lytic vacuole organization
7
18
2.436906
0.014814
P54802,P04062,O14773,Q14108,P50897,P11117,Q12768
Processes and pathways
GO Biological process
msigdb_gobp
98,443,201,19,52,83,308
1812,201,762,443,1096,463,83,1612,52,1422,98,1425,308,19,1999,956,2217,2072
-0.37984219227896826,1.255425828169697,0.2923398612170866,0.6245521818790327,0.0498499651371408,0.5997077106006617,2.1465741639128653,-0.2619266677946719,2.678047917700652,-0.14649000038336524,1.8789142803170127,-0.14649000038336524,0.8669105116207638,4.111237733873485,-0.4699677127277454,0.15895673427969537,-0.6235310490678561,-0.5003402500028168
2,702
Organelle biogenesis and maintenance
19
85
2.430798
0.015066
Q13561,O75964,P62258,P48735,Q9NX63,P06576,Q15648,O75935,Q13885,Q13505,P04350,A0AVF1,P56385,Q9BVA1,Q7Z4L5,A6NIH7,P07437,O43924,P68371
Processes and pathways
Reactome Pathways
msigdb_reactome
261,256,257,17,290,292,304,180,190,64,210,208,347,220,97,101,105,235,124
208,101,760,2545,235,461,854,180,1136,256,1460,1219,792,210,1220,292,105,1768,1270,1012,1818,2326,2527,621,896,1314,1565,1015,1466,2518,1370,2499,17,2040,2197,2041,1990,2122,798,369,347,1784,1679,627,257,124,1181,1059,542,1110,2048,64,261,190,1518,944,1947,1233,304,712,1434,2308,485,1118,774,2206,97,2642,807,1390,1479,1639,777,873,1074,603,1482,220,1647,692,757,290,1705,613,1490
1.2333342498208812,1.8592673659235324,0.2923398612170866,-1.0776690173461208,1.0988376535312658,0.5997077106006617,0.2127025180887077,1.3645361307346424,0.02222921008355008,1.0303037635203478,-0.17512221304650355,-0.03343454335768025,0.2659233011870234,1.2333342498208812,-0.03343454335768025,0.9141025725456303,1.8395473434978173,-0.350125356105606,-0.06148029559266701,0.10467597056101892,-0.37984219227896826,-0.7495318851344548,-1.0439690553345753,0.4225314103597223,0.18589586847145548,-0.08967050071108885,-0.2328390217993925,0.10467597056101892,-0.17512221304650355,-1.0104720506565676,-0.1180065861783075,-0.977175681919584,4.123983608212495,-0.5003402500028168,-0.6235310490678561,-0.5003402500028168,-0.4699677127277454,-0.5615918989070766,0.2659233011870234,0.747090864182487,0.7953385242734627,-0.350125356105606,-0.2911692129463672,0.4225314103597223,1.0303037635203478,1.6586894203500797,-0.005531837066441173,0.07733177575208161,0.49917415125399284,0.0498499651371408,-0.5003402500028168,2.3477474020211564,1.0303037635203478,1.3428914236840213,-0.2039047156366997,0.15895673427969537,-0.43976167580769304,-0.03343454335768025,0.890558218300318,0.3447912610633156,-0.14649000038336524,-0.7177615370892623,0.5747486913303033,0.0498499651371408,0.2923398612170866,-0.6235310490678561,1.8984886025018775,-1.6092322015717255,0.2659233011870234,-0.1180065861783075,-0.17512221304650355,-0.2619266677946719,0.2923398612170866,0.2127025180887077,0.07733177575208161,0.4481994586006217,-0.17512221304650355,1.1888758808001145,-0.2619266677946719,0.37082842982646413,0.31862879037972053,0.9375444335085626,-0.2911692129463672,0.4481994586006217,-0.17512221304650355
2,702
Signaling
8
16
2.42363
0.015366
Q96PC5,O00264,Q8WUJ1,Q7Z4V5,Q13123,Q5JRA6,O15173,P43490
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
324,255,13,526,567,545,187,287
255,187,929,1828,287,565,1283,567,1379,545,526,1066,13,324,1077,1923
1.0303037635203478,1.3428914236840213,0.15895673427969537,-0.37984219227896826,0.9375444335085626,0.473746678395286,-0.06148029559266701,0.473746678395286,-0.1180065861783075,0.49917415125399284,0.5244829444562599,0.07733177575208161,4.212322514130888,0.8431585826801586,0.07733177575208161,-0.4097204049195783
2,702
Intrinsic component of organelle membrane
30
111
2.415639
0.015708
P10321,Q99595,Q8N766,Q9BPX6,A0FGR8,Q8TCT8,Q9Y282,Q9P2E9,O15118,Q9NX63,O75880,Q14318,Q9Y2R0,Q13505,Q8N2H4,L0R6Q1,Q6P4A7,O75844,Q86XL3,P42892,Q9Y2U8,O75431,Q9BUN8,Q15388,O43505,Q15070,Q14739,Q16891,Q96NB2,Q9NQC3
Localization
GO Cellular component
msigdb_gocc
376,5,527,139,389,144,145,423,24,290,296,430,56,64,199,440,75,74,206,80,353,461,215,86,96,224,359,485,511,514
389,440,1301,852,24,2183,1869,1359,96,1131,461,74,296,2032,966,1498,648,2658,699,2414,376,1980,1270,1503,1561,671,1718,734,1466,80,1422,1832,1058,1509,2157,1680,2127,1786,828,1996,64,430,359,1738,224,86,1893,908,1379,485,867,1527,1118,2052,75,774,945,833,206,2100,682,989,1692,199,836,527,2235,1743,528,144,717,1744,1954,1244,2665,511,1591,5,139,915,1443,2010,215,1482,1204,2429,1294,2636,608,2019,1702,514,757,290,2173,1253,609,423,660,1297,694,919,643,2176,145,56,353,1864,644,1490,1548
0.698408241052304,0.6245521818790327,-0.08967050071108885,0.2127025180887077,3.530739879481159,-0.6235310490678561,-0.4097204049195783,-0.1180065861783075,1.9374215068382623,0.02222921008355008,0.5997077106006617,2.2206204495029636,0.890558218300318,-0.5003402500028168,0.13188385952514886,-0.2039047156366997,0.39674143767950243,-1.8368287909913394,0.3447912610633156,-0.8459514851409792,0.7228043903765459,-0.4699677127277454,-0.06148029559266701,-0.2039047156366997,-0.2328390217993925,0.37082842982646413,-0.32056824010222307,0.31862879037972053,-0.17512221304650355,2.202206192643275,-0.14649000038336524,-0.37984219227896826,0.07733177575208161,-0.2039047156366997,-0.5924746168808616,-0.2911692129463672,-0.5615918989070766,-0.350125356105606,0.23937792178355133,-0.4699677127277454,2.3477474020211564,0.6492831048866388,0.7712686001756313,-0.32056824010222307,1.1665076288666967,2.0714733698385936,-0.4097204049195783,0.18589586847145548,-0.1180065861783075,0.5747486913303033,0.2127025180887077,-0.2039047156366997,0.0498499651371408,-0.5003402500028168,2.2206204495029636,0.2923398612170866,0.15895673427969537,0.23937792178355133,1.255425828169697,-0.5308810490428666,0.37082842982646413,0.13188385952514886,-0.2911692129463672,1.2774266291404368,0.23937792178355133,0.5244829444562599,-0.654763070997487,-0.32056824010222307,0.5244829444562599,1.5346059932631821,0.3447912610633156,-0.32056824010222307,-0.43976167580769304,-0.03343454335768025,-1.9147862223575949,0.5496741112974982,-0.2328390217993925,5.198120334434664,1.5762892971839588,0.18589586847145548,-0.14649000038336524,-0.4699677127277454,1.2111511761503668,-0.17512221304650355,-0.005531837066441173,-0.8459514851409792,-0.06148029559266701,-1.5353706399979128,0.4481994586006217,-0.4699677127277454,-0.2911692129463672,0.5496741112974982,0.31862879037972053,0.9375444335085626,-0.5924746168808616,-0.03343454335768025,0.4481994586006217,0.673901466516914,0.39674143767950243,-0.06148029559266701,0.37082842982646413,0.18589586847145548,0.4225314103597223,-0.5924746168808616,1.5346059932631821,2.489366453233105,0.7953385242734627,-0.37984219227896826,0.4225314103597223,-0.17512221304650355,-0.2039047156366997
2,702
Regulation of rna splicing
32
79
2.408525
0.016017
P84103,P52597,Q07955,Q9Y2W1,P31943,Q13573,Q9UHX1,Q96MU7,P35637,Q9BWF3,P98175,P17844,Q07666,P38159,P61978,P31942,Q96T37,O75494,Q92879,P51116,P51114,P62995,Q08170,P22626,P19338,Q09666,Q5BKZ1,Q16629,P98179,Q13242,Q8NDT2,Q13247
Processes and pathways
GO Biological process
msigdb_gobp
500,626,260,405,395,520,553,684,155,687,416,537,678,176,301,298,450,558,600,71,203,465,593,345,344,594,227,633,106,370,245,249
1352,1455,558,1606,891,892,1817,537,1770,344,345,1505,971,1363,1877,1985,298,395,155,176,1275,825,203,71,1105,626,673,1227,799,301,2125,465,2443,500,416,106,1729,2444,974,678,260,593,1230,594,801,1577,370,802,249,520,1732,1187,2049,1474,1234,2425,633,1327,227,947,776,2408,245,1243,600,914,684,1589,1440,1909,450,687,1401,1251,553,1169,1596,405,1707
-0.1180065861783075,-0.17512221304650355,0.473746678395286,-0.2619266677946719,0.18589586847145548,0.18589586847145548,-0.37984219227896826,0.49917415125399284,-0.350125356105606,0.7953385242734627,0.7953385242734627,-0.2039047156366997,0.13188385952514886,-0.1180065861783075,-0.4097204049195783,-0.4699677127277454,0.890558218300318,0.698408241052304,1.4714633126430223,1.386093528320324,-0.06148029559266701,0.23937792178355133,1.255425828169697,2.2572569188414064,0.0498499651371408,0.4225314103597223,0.37082842982646413,-0.03343454335768025,0.2659233011870234,0.890558218300318,-0.5615918989070766,0.5997077106006617,-0.8784677570852006,0.5496741112974982,0.673901466516914,1.8395473434978173,-0.32056824010222307,-0.8784677570852006,0.13188385952514886,0.37082842982646413,1.0303037635203478,0.4481994586006217,-0.03343454335768025,0.4481994586006217,0.2659233011870234,-0.2328390217993925,0.747090864182487,0.2659233011870234,1.0532456836169948,0.5244829444562599,-0.32056824010222307,-0.005531837066441173,-0.5003402500028168,-0.17512221304650355,-0.03343454335768025,-0.8459514851409792,0.4225314103597223,-0.08967050071108885,1.1440456767678313,0.15895673427969537,0.2923398612170866,-0.8136248100970255,1.0760900505966375,-0.03343454335768025,0.4481994586006217,0.18589586847145548,0.37082842982646413,-0.2328390217993925,-0.14649000038336524,-0.4097204049195783,0.6245521818790327,0.37082842982646413,-0.1180065861783075,-0.03343454335768025,0.49917415125399284,0.02222921008355008,-0.2328390217993925,0.698408241052304,-0.2911692129463672
2,702
Carbohydrate derivative transport
9
18
2.395933
0.016578
Q8WTV0,L0R6Q1,O15439,Q99808,P61916,Q8TB61,Q9HC21,P41440,P07602
Processes and pathways
GO Biological process
msigdb_gobp
69,440,267,640,142,528,608,115,57
440,614,267,1131,1048,57,1980,1098,115,142,902,713,528,1586,69,640,608,880
0.6245521818790327,0.4225314103597223,1.0072634916981495,0.02222921008355008,0.07733177575208161,2.436706104734128,-0.4699677127277454,0.0498499651371408,1.7398321727024608,1.5554884161976426,0.18589586847145548,0.3447912610633156,0.5244829444562599,-0.2328390217993925,2.275479978158442,0.4225314103597223,0.4481994586006217,0.2127025180887077
2,702
Sphingolipid metabolism
6
24
2.394134
0.01666
P16278,P10619,P17900,Q13510,P06280,P07602
Processes and pathways
Reactome Pathways
msigdb_reactome
128,163,70,111,149,57
389,727,2074,926,1264,648,443,149,168,57,1096,163,128,70,669,1180,677,111,1380,2666,915,1651,880,1296
0.698408241052304,0.31862879037972053,-0.5308810490428666,0.15895673427969537,-0.06148029559266701,0.39674143767950243,0.6245521818790327,1.4925940643576996,1.4075642865122227,2.436706104734128,0.0498499651371408,1.4289490678170462,1.638208714171853,2.2572569188414064,0.37082842982646413,-0.005531837066441173,0.37082842982646413,1.7799433878907398,-0.1180065861783075,-1.9147862223575949,0.18589586847145548,-0.2619266677946719,0.2127025180887077,-0.06148029559266701
2,702
Membrane trafficking regulatory protein
7
18
2.391918
0.016761
O00560,O43760,P11279,P24390,Q9UNZ2,P55735,P50542
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
130,73,236,21,328,380,379
1410,130,73,442,1264,236,21,379,380,864,1287,2057,1196,875,2379,1296,2217,328
-0.14649000038336524,1.6176488501837785,2.2389705497371217,0.6245521818790327,-0.06148029559266701,1.0988376535312658,3.6717230671513654,0.7228043903765459,0.7228043903765459,0.2127025180887077,-0.06148029559266701,-0.5003402500028168,-0.005531837066441173,0.2127025180887077,-0.7814856320202566,-0.06148029559266701,-0.6235310490678561,0.8431585826801586
2,702
Muscle weakness
48
247
2.383703
0.017139
Q15165,P50542,O43772,P51812,Q9BPX6,Q9Y263,Q99720,P11310,Q15067,Q9NWM8,Q9NQT5,P35637,P00403,O95831,P06865,Q86U42,P61978,Q70HW3,O96000,P06753,Q12768,P07602,Q13126,Q5KU26,P53680,P17900,P07196,P51114,Q99496,Q8N0X7,O14979,P23786,O15460,P22626,P40855,O43505,Q14739,P52815,O95721,Q9BUK6,Q13510,P50402,P41440,O60313,Q8WWQ0,Q92804,Q6DKK2,O43676
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
262,379,10,11,139,140,14,141,274,153,152,155,35,39,168,305,301,49,172,297,308,57,62,66,318,70,315,203,335,333,330,88,89,345,223,96,359,357,104,108,111,367,115,363,119,250,126,127
1085,2142,614,1974,2522,1353,1175,330,727,2074,89,96,127,926,10,1872,363,1601,816,1361,730,2353,1456,2324,646,616,664,1415,1264,1931,104,39,172,700,35,2478,374,2577,1461,1266,2640,968,2458,857,297,168,315,2189,57,1096,1177,2513,1934,891,463,1010,765,141,1979,1980,477,1223,1558,1012,70,2149,1771,499,1716,1717,2415,345,2080,88,1272,1719,1315,1985,1776,672,1224,2529,155,1566,936,2417,1879,1986,1780,2599,2460,223,2328,1468,1826,115,1140,1469,1569,2518,796,1880,2500,2085,2461,1615,590,2331,367,379,900,738,203,1422,2086,1990,2042,11,1017,357,2485,318,2198,2156,2088,1882,1572,1677,2298,1836,2370,301,627,827,1994,466,654,1787,1839,2630,1148,1149,1110,1886,308,1888,62,1021,111,2093,944,1947,2305,1891,1520,359,632,2273,274,830,977,262,831,1433,908,978,1190,1581,867,1382,805,66,1064,1582,1118,126,2098,713,1478,1028,524,49,1691,505,305,2465,807,333,949,1743,2101,1121,1744,119,547,1198,250,1851,1587,2005,601,2610,1696,1247,335,1911,1644,14,1592,139,844,781,1443,686,2520,603,108,1344,689,1204,606,608,1918,152,453,1650,153,880,1808,532,1652,1212,1757,1923,1405,553,140,2023,2219,1215,2070,1809,644,1598,2595,1971,494
0.0498499651371408,-0.5924746168808616,0.4225314103597223,-0.4699677127277454,-1.0439690553345753,-0.1180065861783075,-0.005531837066441173,0.8193015508006276,0.31862879037972053,-0.5308810490428666,2.0335184987881214,1.9374215068382623,1.638208714171853,0.15895673427969537,4.396604319498196,-0.4097204049195783,0.747090864182487,-0.2619266677946719,0.23937792178355133,-0.1180065861783075,0.31862879037972053,-0.7814856320202566,-0.17512221304650355,-0.7495318851344548,0.39674143767950243,0.4225314103597223,0.37082842982646413,-0.14649000038336524,-0.06148029559266701,-0.43976167580769304,1.8395473434978173,2.9408710467958437,1.386093528320324,0.3447912610633156,3.1141580717849924,-0.9440776667177786,0.7228043903765459,-1.2145462814230732,-0.17512221304650355,-0.06148029559266701,-1.6092322015717255,0.13188385952514886,-0.9111757607706441,0.2127025180887077,0.890558218300318,1.4075642865122227,0.8431585826801586,-0.6235310490678561,2.436706104734128,0.0498499651371408,-0.005531837066441173,-1.0104720506565676,-0.43976167580769304,0.18589586847145548,0.5997077106006617,0.10467597056101892,0.2923398612170866,1.5554884161976426,-0.4699677127277454,-0.4699677127277454,0.5747486913303033,-0.03343454335768025,-0.2328390217993925,0.10467597056101892,2.2572569188414064,-0.5924746168808616,-0.350125356105606,0.5496741112974982,-0.32056824010222307,-0.32056824010222307,-0.8459514851409792,0.7953385242734627,-0.5308810490428666,2.0525300254302943,-0.06148029559266701,-0.32056824010222307,-0.08967050071108885,-0.4699677127277454,-0.350125356105606,0.37082842982646413,-0.03343454335768025,-1.0439690553345753,1.4714633126430223,-0.2328390217993925,0.15895673427969537,-0.8459514851409792,-0.4097204049195783,-0.4699677127277454,-0.350125356105606,-1.2842660323097124,-0.9111757607706441,1.1665076288666967,-0.7495318851344548,-0.17512221304650355,-0.37984219227896826,1.7398321727024608,0.02222921008355008,-0.17512221304650355,-0.2328390217993925,-1.0104720506565676,0.2659233011870234,-0.4097204049195783,-0.977175681919584,-0.5308810490428666,-0.9111757607706441,-0.2619266677946719,0.4481994586006217,-0.7495318851344548,0.747090864182487,0.7228043903765459,0.18589586847145548,0.31862879037972053,1.255425828169697,-0.14649000038336524,-0.5308810490428666,-0.4699677127277454,-0.5003402500028168,4.3359171716292355,0.10467597056101892,0.7712686001756313,-0.9440776667177786,0.8431585826801586,-0.6235310490678561,-0.5924746168808616,-0.5308810490428666,-0.4097204049195783,-0.2328390217993925,-0.2911692129463672,-0.7177615370892623,-0.37984219227896826,-0.7814856320202566,0.890558218300318,0.4225314103597223,0.23937792178355133,-0.4699677127277454,0.5997077106006617,0.39674143767950243,-0.350125356105606,-0.37984219227896826,-1.4624695189023518,0.02222921008355008,0.02222921008355008,0.0498499651371408,-0.4097204049195783,0.8669105116207638,-0.4097204049195783,2.365660090880429,0.10467597056101892,1.7799433878907398,-0.5308810490428666,0.15895673427969537,-0.43976167580769304,-0.7177615370892623,-0.4097204049195783,-0.2039047156366997,0.7712686001756313,0.4225314103597223,-0.6861725882485472,0.9841240598522195,0.23937792178355133,0.13188385952514886,1.0303037635203478,0.23937792178355133,-0.14649000038336524,0.18589586847145548,0.13188385952514886,-0.005531837066441173,-0.2328390217993925,0.2127025180887077,-0.1180065861783075,0.2659233011870234,2.329773449633904,0.07733177575208161,-0.2328390217993925,0.0498499651371408,1.6586894203500797,-0.5308810490428666,0.3447912610633156,-0.17512221304650355,0.10467597056101892,0.5244829444562599,2.745005746127423,-0.2911692129463672,0.5496741112974982,0.890558218300318,-0.9111757607706441,0.2659233011870234,0.8193015508006276,0.15895673427969537,-0.32056824010222307,-0.5308810490428666,0.0498499651371408,-0.32056824010222307,1.7196623603455143,0.49917415125399284,-0.005531837066441173,1.0532456836169948,-0.37984219227896826,-0.2328390217993925,-0.4699677127277454,0.4481994586006217,-1.3194551620520436,-0.2911692129463672,-0.03343454335768025,0.8193015508006276,-0.4097204049195783,-0.2619266677946719,4.199796153109882,-0.2328390217993925,1.5762892971839588,0.23937792178355133,0.2923398612170866,-0.14649000038336524,0.37082842982646413,-1.0104720506565676,0.4481994586006217,1.8197536917866635,-0.08967050071108885,0.37082842982646413,-0.005531837066441173,0.4481994586006217,0.4481994586006217,-0.4097204049195783,1.4925940643576996,0.6245521818790327,-0.2619266677946719,1.4925940643576996,0.2127025180887077,-0.350125356105606,0.5244829444562599,-0.2619266677946719,-0.005531837066441173,-0.32056824010222307,-0.4097204049195783,-0.1180065861783075,0.49917415125399284,1.5762892971839588,-0.4699677127277454,-0.6235310490678561,-0.005531837066441173,-0.5003402500028168,-0.350125356105606,0.4225314103597223,-0.2328390217993925,-1.2492972789568666,-0.43976167580769304,0.5747486913303033
2,702
EF-Hand 1, calcium-binding site [IPR018247]
9
31
2.373969
0.017598
Q9UBV8,Q9BPX6,P43304,Q15293,O43852,Q14257,P80303,Q9NWM8,Q9Y680
Sequence
InterPro Binding site
interpro_binding_site
77,139,42,82,179,116,118,153,221
887,179,2353,889,818,2189,1050,2653,444,1312,2118,623,1568,42,118,244,2602,903,116,2160,82,713,989,1692,509,139,1079,153,77,724,221
0.18589586847145548,1.3645361307346424,-0.7814856320202566,0.18589586847145548,0.23937792178355133,-0.6235310490678561,0.07733177575208161,-1.7218791207703874,0.6245521818790327,-0.08967050071108885,-0.5615918989070766,0.4225314103597223,-0.2328390217993925,2.827512784417395,1.7196623603455143,1.0760900505966375,-1.2842660323097124,0.18589586847145548,1.7398321727024608,-0.5924746168808616,2.183727349455117,0.3447912610633156,0.13188385952514886,-0.2911692129463672,0.5496741112974982,1.5762892971839588,0.07733177575208161,1.4925940643576996,2.2206204495029636,0.3447912610633156,1.1888758808001145
2,702
External side of plasma membrane
10
20
2.365411
0.01801
O15439,P42892,P11279,P41440,Q9H2H9,O96005,P02786,P08183,P00813,P00390
Localization
GO Cellular component
msigdb_gocc
267,80,236,115,84,243,343,189,93,286
267,965,243,286,93,343,583,619,858,189,236,2552,671,115,80,2194,368,2591,522,84
1.0072634916981495,0.13188385952514886,1.0760900505966375,0.9375444335085626,1.9760700997311131,0.7953385242734627,0.4481994586006217,0.4225314103597223,0.2127025180887077,1.3428914236840213,1.0988376535312658,-1.1115742979561345,0.37082842982646413,1.7398321727024608,2.202206192643275,-0.6235310490678561,0.747090864182487,-1.2492972789568666,0.5244829444562599,2.090348997439926
2,702
Vesicles
40
249
2.358457
0.018351
P42785,P16278,P30519,Q8NCC3,Q8TCT8,P24390,Q9UL15,O15118,Q8N8N7,Q8N4Q0,P21964,P10619,Q9NPR9,O95487,P06865,Q8NBX0,P13674,P50897,P07602,Q8N1G2,Q5KU26,Q32P28,Q8WTV0,P17900,Q96JB5,Q9Y487,Q9UBV8,Q6P4A7,Q9NRY5,O15460,Q96K76,Q3SXM5,O75153,Q9HD20,Q99538,Q5BKZ1,P38571,Q9UPN9,O14976,P11717
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
0,128,3,134,144,21,154,24,27,157,34,163,166,167,168,41,173,52,57,191,66,68,69,70,200,78,77,75,85,89,90,219,222,252,99,227,233,241,117,120
1658,1973,614,790,2691,2475,1868,117,1355,285,1260,24,2183,2476,89,1709,1978,496,222,2144,1455,1457,731,965,2032,1555,1092,1498,1557,167,2497,1711,2188,582,1932,168,57,701,424,409,2514,821,463,163,892,120,2598,173,894,2434,128,1051,70,1561,823,34,21,1608,1936,1563,1506,1273,3,1366,2670,766,2554,233,1780,1825,651,1612,1568,0,1056,1721,2498,1141,1723,2193,1941,590,52,368,1782,1277,1675,1278,2044,938,1834,1676,1616,380,2370,2157,1425,541,2199,2533,1726,415,1994,331,654,942,902,482,1514,1231,1517,1428,1628,1732,2591,903,1430,1232,743,484,595,1844,904,1739,2654,2376,596,2536,1632,710,866,1327,68,219,2519,2558,867,227,545,1475,66,1383,981,1329,1999,2406,2053,75,2054,1850,2099,1691,2275,361,2100,834,2615,1901,835,1585,191,157,2447,27,41,2426,134,1637,1479,528,144,69,599,1195,1393,2699,1198,1641,272,1587,529,2449,1695,993,1956,1907,1908,200,90,1074,510,1397,841,779,1643,99,2492,325,1803,1249,1857,995,2104,2059,2450,2647,2137,1958,1915,386,326,1917,252,265,2612,166,2574,641,2020,85,787,1861,2171,1537,2583,515,1167,1254,77,788,2594,2411,2452,723,154,695,1759,1004,241,1705,457,2244,78,1043,1598,406,1548,2512,2246
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2,702
Cristae formation
7
20
2.357542
0.018396
Q13505,Q9NX63,O75964,P06576,P56134,O75431,P56385
Processes and pathways
Reactome Pathways
msigdb_reactome
64,290,256,292,369,461,347
461,1136,256,292,1270,621,896,1015,1466,1370,369,347,64,485,1118,774,1482,757,290,1490
0.5997077106006617,0.02222921008355008,1.0303037635203478,0.9141025725456303,-0.06148029559266701,0.4225314103597223,0.18589586847145548,0.10467597056101892,-0.17512221304650355,-0.1180065861783075,0.747090864182487,0.7953385242734627,2.3477474020211564,0.5747486913303033,0.0498499651371408,0.2923398612170866,-0.17512221304650355,0.31862879037972053,0.9375444335085626,-0.17512221304650355
2,702
Proton transmembrane transporter activity
17
34
2.357344
0.018406
P61421,P00403,O75964,P06576,P13073,Q9Y487,P51790,Q93050,P08574,Q13423,P56134,P20674,Q9Y5K8,O00400,P56385,Q7KZN9,P24539
Functions
GO Molecular function
msigdb_gomf
414,35,256,292,477,78,368,529,666,177,369,649,388,614,347,504,621
614,1136,256,818,35,1048,292,666,1268,1980,477,649,823,1772,621,896,2364,1015,898,1780,1370,368,369,347,414,1786,177,504,529,1956,721,1348,78,388
0.4225314103597223,0.02222921008355008,1.0303037635203478,0.23937792178355133,3.1141580717849924,0.07733177575208161,0.9141025725456303,0.37082842982646413,-0.06148029559266701,-0.4699677127277454,0.5747486913303033,0.39674143767950243,0.23937792178355133,-0.350125356105606,0.4225314103597223,0.18589586847145548,-0.7814856320202566,0.10467597056101892,0.18589586847145548,-0.350125356105606,-0.1180065861783075,0.747090864182487,0.747090864182487,0.7953385242734627,0.673901466516914,-0.350125356105606,1.386093528320324,0.5496741112974982,0.5244829444562599,-0.43976167580769304,0.3447912610633156,-0.08967050071108885,2.2206204495029636,0.7228043903765459
2,702
Regulation of alternative mrna splicing via spliceosome
15
29
2.351427
0.018702
Q92879,Q9Y2W1,P17844,P51116,Q07666,P51114,P38159,P62995,Q8NDT2,Q96T37,Q9UHX1,Q96MU7,Q13247,Q9BWF3,P98175
Processes and pathways
GO Biological process
msigdb_gobp
600,405,537,71,678,203,176,465,245,450,553,684,249,687,416
1352,891,1817,537,1363,1985,176,825,203,71,1105,673,465,416,1729,678,249,1474,1327,776,245,1243,600,684,450,687,553,405,1707
-0.1180065861783075,0.18589586847145548,-0.37984219227896826,0.49917415125399284,-0.1180065861783075,-0.4699677127277454,1.386093528320324,0.23937792178355133,1.255425828169697,2.2572569188414064,0.0498499651371408,0.37082842982646413,0.5997077106006617,0.673901466516914,-0.32056824010222307,0.37082842982646413,1.0532456836169948,-0.17512221304650355,-0.08967050071108885,0.2923398612170866,1.0760900505966375,-0.03343454335768025,0.4481994586006217,0.37082842982646413,0.6245521818790327,0.37082842982646413,0.49917415125399284,0.698408241052304,-0.2911692129463672
2,702
Constitutional symptom
39
202
2.348736
0.018837
Q15165,Q9NZ08,Q02241,P51812,Q99720,P11310,P48735,Q14108,Q96HY6,Q12769,P06280,P35637,P21964,P28070,Q14566,Q13423,Q70HW3,P06753,O75874,Q12768,P07602,P53680,P07196,Q99496,O75844,P42892,Q8NFH4,Q9Y2U8,P23786,O15460,P22626,P14174,Q14739,Q9BUK6,Q13510,P50402,O60313,Q01844,Q92804
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
262,135,258,11,14,141,17,19,276,280,149,155,34,159,36,177,49,297,54,308,57,318,315,335,74,80,212,353,88,89,345,218,359,108,111,367,363,382,250
1351,790,1974,2475,1353,1175,727,2074,89,926,887,2648,363,1601,557,964,74,54,1264,2188,2478,374,443,2577,1266,2568,149,2078,857,297,315,2189,57,1096,1177,1666,891,1010,765,2669,1097,1269,141,1222,2564,1980,218,444,894,586,1012,1769,1502,2385,1670,499,1716,1717,34,1052,2415,345,2036,88,1504,2152,671,159,2191,1719,1315,2119,1776,1367,1937,155,1465,936,2417,1419,2599,2460,2328,1468,80,796,1056,1369,2588,17,2194,1615,367,900,738,2086,1990,2042,11,2395,1782,826,2044,2368,318,1834,2088,1882,1572,705,2486,2335,1624,427,1147,382,258,1471,428,1839,974,2268,1149,828,308,280,1888,655,1021,1842,1322,177,111,2093,19,1060,944,2305,36,1735,359,632,680,543,977,262,2403,1846,804,2404,1190,2446,1581,867,1478,524,49,1691,506,635,1794,507,212,1242,1744,1069,547,1031,2236,250,872,1587,2005,601,276,335,1911,14,1443,686,108,1341,689,1487,1700,606,453,135,880,2316,1041,611,1405,661,812,2495,353,1810,1864,1407,1598,494
-0.1180065861783075,0.2659233011870234,-0.4699677127277454,-0.9440776667177786,-0.1180065861783075,-0.005531837066441173,0.31862879037972053,-0.5308810490428666,2.0335184987881214,0.15895673427969537,0.18589586847145548,-1.6840786597335329,0.747090864182487,-0.2619266677946719,0.473746678395286,0.13188385952514886,2.2206204495029636,2.558767311500275,-0.06148029559266701,-0.6235310490678561,-0.9440776667177786,0.7228043903765459,0.6245521818790327,-1.2145462814230732,-0.06148029559266701,-1.1800104648843361,1.4925940643576996,-0.5308810490428666,0.2127025180887077,0.890558218300318,0.8431585826801586,-0.6235310490678561,2.436706104734128,0.0498499651371408,-0.005531837066441173,-0.2911692129463672,0.18589586847145548,0.10467597056101892,0.2923398612170866,-2.0740082524478405,0.0498499651371408,-0.06148029559266701,1.5554884161976426,-0.03343454335768025,-1.1456872992127736,-0.4699677127277454,1.1888758808001145,0.6245521818790327,0.18589586847145548,0.4481994586006217,0.10467597056101892,-0.350125356105606,-0.2039047156366997,-0.8136248100970255,-0.2911692129463672,0.5496741112974982,-0.32056824010222307,-0.32056824010222307,3.1296283127460667,0.07733177575208161,-0.8459514851409792,0.7953385242734627,-0.5003402500028168,2.0525300254302943,-0.2039047156366997,-0.5924746168808616,0.37082842982646413,1.4502485272895491,-0.6235310490678561,-0.32056824010222307,-0.08967050071108885,-0.5615918989070766,-0.350125356105606,-0.1180065861783075,-0.43976167580769304,1.4714633126430223,-0.17512221304650355,0.15895673427969537,-0.8459514851409792,-0.14649000038336524,-1.2842660323097124,-0.9111757607706441,-0.7495318851344548,-0.17512221304650355,2.202206192643275,0.2659233011870234,0.07733177575208161,-0.1180065861783075,-1.2492972789568666,4.123983608212495,-0.6235310490678561,-0.2619266677946719,0.747090864182487,0.18589586847145548,0.31862879037972053,-0.5308810490428666,-0.4699677127277454,-0.5003402500028168,4.3359171716292355,-0.8136248100970255,-0.350125356105606,0.23937792178355133,-0.5003402500028168,-0.7814856320202566,0.8431585826801586,-0.37984219227896826,-0.5308810490428666,-0.4097204049195783,-0.2328390217993925,0.3447912610633156,-0.9440776667177786,-0.7495318851344548,-0.2619266677946719,0.6492831048866388,0.02222921008355008,0.7228043903765459,1.0303037635203478,-0.17512221304650355,0.6492831048866388,-0.37984219227896826,0.13188385952514886,-0.6861725882485472,0.02222921008355008,0.23937792178355133,0.8669105116207638,0.9608846498386505,-0.4097204049195783,0.39674143767950243,0.10467597056101892,-0.37984219227896826,-0.08967050071108885,1.386093528320324,1.7799433878907398,-0.5308810490428666,4.111237733873485,0.07733177575208161,0.15895673427969537,-0.7177615370892623,3.0045553572629977,-0.32056824010222307,0.7712686001756313,0.4225314103597223,0.37082842982646413,0.49917415125399284,0.13188385952514886,1.0303037635203478,-0.8136248100970255,-0.37984219227896826,0.2659233011870234,-0.8136248100970255,-0.005531837066441173,-0.8784677570852006,-0.2328390217993925,0.2127025180887077,-0.17512221304650355,0.5244829444562599,2.745005746127423,-0.2911692129463672,0.5496741112974982,0.4225314103597223,-0.350125356105606,0.5496741112974982,1.2333342498208812,-0.03343454335768025,-0.32056824010222307,0.07733177575208161,0.49917415125399284,0.10467597056101892,-0.654763070997487,1.0532456836169948,0.2127025180887077,-0.2328390217993925,-0.4699677127277454,0.4481994586006217,0.9841240598522195,0.8193015508006276,-0.4097204049195783,4.199796153109882,-0.14649000038336524,0.37082842982646413,1.8197536917866635,-0.08967050071108885,0.37082842982646413,-0.17512221304650355,-0.2911692129463672,0.4481994586006217,0.6245521818790327,1.5970092420957023,0.2127025180887077,-0.7177615370892623,0.10467597056101892,0.4481994586006217,-0.1180065861783075,0.39674143767950243,0.2659233011870234,-0.9440776667177786,0.7953385242734627,-0.350125356105606,-0.37984219227896826,-0.1180065861783075,-0.2328390217993925,0.5747486913303033
2,702
EF-hand domain [IPR002048]
9
35
2.348305
0.018859
Q9UBV8,Q9BPX6,P43304,Q15293,O43852,Q14257,P80303,Q9NWM8,Q9Y680
Sequence
InterPro Domain
interpro_domain
77,139,42,82,179,116,118,153,221
887,179,2353,889,818,2189,1050,2653,444,1312,2118,623,1568,42,1373,118,244,2602,903,116,2160,82,772,713,989,1692,637,509,139,1079,153,77,812,724,221
0.18589586847145548,1.3645361307346424,-0.7814856320202566,0.18589586847145548,0.23937792178355133,-0.6235310490678561,0.07733177575208161,-1.7218791207703874,0.6245521818790327,-0.08967050071108885,-0.5615918989070766,0.4225314103597223,-0.2328390217993925,2.827512784417395,-0.1180065861783075,1.7196623603455143,1.0760900505966375,-1.2842660323097124,0.18589586847145548,1.7398321727024608,-0.5924746168808616,2.183727349455117,0.2923398612170866,0.3447912610633156,0.13188385952514886,-0.2911692129463672,0.4225314103597223,0.5496741112974982,1.5762892971839588,0.07733177575208161,1.4925940643576996,2.2206204495029636,0.2659233011870234,0.3447912610633156,1.1888758808001145
2,702
Receptor mediated endocytosis
14
50
2.343098
0.019124
O00560,P53680,P09497,P20645,P61978,Q14108,P50897,P09496,P41440,O14976,P11717,P02786,Q5VW38,Q13432
Processes and pathways
GO Biological process
msigdb_gobp
130,318,409,268,301,19,52,424,115,117,120,343,30,161
1973,130,117,1978,2144,965,1555,1711,343,619,560,424,409,120,794,1561,268,1718,1365,115,1568,2394,900,52,318,301,675,2203,1726,1994,1730,161,1428,864,1629,19,1431,1232,1287,30,1333,488,1852,1911,1700,2411,2412,920,1407,1811
-0.4699677127277454,1.6176488501837785,1.7196623603455143,-0.4699677127277454,-0.5924746168808616,0.13188385952514886,-0.2328390217993925,-0.32056824010222307,0.7953385242734627,0.4225314103597223,0.473746678395286,0.6492831048866388,0.673901466516914,1.6994156728204817,0.2659233011870234,-0.2328390217993925,1.0072634916981495,-0.32056824010222307,-0.1180065861783075,1.7398321727024608,-0.2328390217993925,-0.8136248100970255,0.18589586847145548,2.678047917700652,0.8431585826801586,0.890558218300318,0.37082842982646413,-0.6235310490678561,-0.32056824010222307,-0.4699677127277454,-0.32056824010222307,1.4502485272895491,-0.14649000038336524,0.2127025180887077,-0.2619266677946719,4.111237733873485,-0.14649000038336524,-0.03343454335768025,-0.06148029559266701,3.311754425692945,-0.08967050071108885,0.5747486913303033,-0.37984219227896826,-0.4097204049195783,-0.2911692129463672,-0.8136248100970255,-0.8136248100970255,0.18589586847145548,-0.1180065861783075,-0.350125356105606
2,702
Protease
17
104
2.339657
0.019301
P42785,Q99538,P10619,P22695,Q9NZ08,Q9UIQ6,Q9H3G5,O75844,P55786,P42892,Q13510,Q8N2K0,Q8TCT8,Q8NHP8,Q96K76,Q5BJF2,Q9HB40
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
0,99,163,122,135,45,44,74,92,80,111,113,144,147,90,28,29
1300,1492,2321,201,1870,1007,2075,2324,74,967,343,2189,1933,163,2147,2652,2114,2552,1501,2190,122,2360,2389,1984,2364,2670,1567,937,0,80,1613,2296,2394,737,1105,2590,2645,1227,2156,2396,2419,92,1785,2371,301,769,1575,2630,1110,630,111,1113,1630,2161,303,1522,2307,2378,1847,28,546,1791,772,2537,1792,1897,332,113,147,1334,1241,144,717,1954,282,1199,1032,489,874,952,2007,1200,90,2311,876,1247,2593,99,780,452,44,2014,29,454,1404,135,1863,848,2064,45,1446,644,2026,472
-0.08967050071108885,-0.2039047156366997,-0.7495318851344548,1.255425828169697,-0.4097204049195783,0.10467597056101892,-0.5308810490428666,-0.7495318851344548,2.2206204495029636,0.13188385952514886,0.7953385242734627,-0.6235310490678561,-0.43976167580769304,1.4289490678170462,-0.5924746168808616,-1.7218791207703874,-0.5615918989070766,-1.1115742979561345,-0.2039047156366997,-0.6235310490678561,1.6586894203500797,-0.7814856320202566,-0.8136248100970255,-0.4699677127277454,-0.7814856320202566,-2.0740082524478405,-0.2328390217993925,0.15895673427969537,6.217718739388483,2.202206192643275,-0.2619266677946719,-0.7177615370892623,-0.8136248100970255,0.31862879037972053,0.0498499651371408,-1.2492972789568666,-1.646530754259767,-0.03343454335768025,-0.5924746168808616,-0.8136248100970255,-0.8459514851409792,2.0144383197469633,-0.350125356105606,-0.7814856320202566,0.890558218300318,0.2923398612170866,-0.2328390217993925,-1.4624695189023518,0.0498499651371408,0.4225314103597223,1.7799433878907398,0.0498499651371408,-0.2619266677946719,-0.5924746168808616,0.890558218300318,-0.2039047156366997,-0.7177615370892623,-0.7814856320202566,-0.37984219227896826,3.3710652583540575,0.49917415125399284,-0.350125356105606,0.2923398612170866,-1.0439690553345753,-0.350125356105606,-0.4097204049195783,0.8193015508006276,1.7599256653622593,1.5136414157872253,-0.08967050071108885,-0.03343454335768025,1.5346059932631821,0.3447912610633156,-0.43976167580769304,0.9608846498386505,-0.005531837066441173,0.10467597056101892,0.5747486913303033,0.2127025180887077,0.15895673427969537,-0.4699677127277454,-0.005531837066441173,2.0335184987881214,-0.7177615370892623,0.2127025180887077,-0.03343454335768025,-1.2492972789568666,1.8789142803170127,0.2923398612170866,0.6245521818790327,2.827512784417395,-0.4699677127277454,3.341494967883903,0.6245521818790327,-0.1180065861783075,1.5970092420957023,-0.37984219227896826,0.23937792178355133,-0.5003402500028168,2.827512784417395,-0.14649000038336524,0.4225314103597223,-0.4699677127277454,0.5997077106006617
2,702
Diarrhea
15
53
2.336678
0.019456
P54802,P00403,Q14566,Q02241,Q08J23,P38571,Q15904,Q14790,P11310,Q13423,P42892,Q13510,P15586,P06280,P00813
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,35,36,258,40,233,234,303,141,177,80,111,174,149,93
816,2561,2477,35,93,343,1266,149,1096,584,141,174,1769,1770,1504,1823,1465,936,233,1468,2517,80,1369,1057,98,704,2335,258,40,177,111,36,2535,303,977,2657,234,503,2446,1634,2572,2205,1069,2168,874,1244,2593,844,1958,1700,1652,812,1447
0.23937792178355133,-1.1456872992127736,-0.9440776667177786,3.1141580717849924,1.9760700997311131,0.7953385242734627,-0.06148029559266701,1.4925940643576996,0.0498499651371408,0.4481994586006217,1.5554884161976426,1.386093528320324,-0.350125356105606,-0.350125356105606,-0.2039047156366997,-0.37984219227896826,-0.17512221304650355,0.15895673427969537,1.1214892721063172,-0.17512221304650355,-1.0104720506565676,2.202206192643275,-0.1180065861783075,0.07733177575208161,1.8789142803170127,0.3447912610633156,-0.7495318851344548,1.0303037635203478,2.892590824162729,1.386093528320324,1.7799433878907398,3.0045553572629977,-1.0439690553345753,0.890558218300318,0.13188385952514886,-1.7982508277275122,1.1214892721063172,0.5496741112974982,-0.8784677570852006,-0.2619266677946719,-1.1800104648843361,-0.6235310490678561,0.07733177575208161,-0.5924746168808616,0.2127025180887077,-0.03343454335768025,-1.2492972789568666,0.23937792178355133,-0.43976167580769304,-0.2911692129463672,-0.2619266677946719,0.2659233011870234,-0.14649000038336524
2,702
Autophagy
8
38
2.334247
0.019583
Q9NS69,P08670,Q8N4H5,P04350,Q15388,P68371,Q13885,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
6,202,138,210,86,124,190,31
1976,815,615,966,699,210,1768,1416,202,892,587,31,1612,379,798,1882,674,768,2580,124,2048,190,1947,86,1999,682,138,1122,572,2593,2492,754,603,220,6,2381,2072,1216
-0.4699677127277454,0.23937792178355133,0.4225314103597223,0.13188385952514886,0.3447912610633156,1.2333342498208812,-0.350125356105606,-0.14649000038336524,1.255425828169697,0.18589586847145548,0.4481994586006217,3.281841750088034,-0.2619266677946719,0.7228043903765459,0.2659233011870234,-0.4097204049195783,0.37082842982646413,0.2923398612170866,-1.2145462814230732,1.6586894203500797,-0.5003402500028168,1.3428914236840213,-0.43976167580769304,2.0714733698385936,-0.4699677127277454,0.37082842982646413,1.5762892971839588,0.0498499651371408,0.473746678395286,-1.2492972789568666,-0.9440776667177786,0.31862879037972053,0.4481994586006217,1.1888758808001145,4.890473754334426,-0.7814856320202566,-0.5003402500028168,-0.005531837066441173
2,702
Abnormal vertebral morphology
12
93
2.331586
0.019723
P16278,P54802,P10619,Q32P28,O95831,O60568,P51812,P48735,Q14108,O75874,Q9NSE4,P00813
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,98,163,68,39,136,11,17,19,54,87,93
1351,2143,2475,1353,1450,2648,1263,1133,136,2290,518,54,818,39,407,93,443,582,858,701,163,1010,2653,174,128,1051,1770,823,2257,1716,2035,2081,1776,1564,1937,1565,1567,1466,1467,1369,17,1016,2042,11,98,705,2335,301,2301,1624,940,741,2399,654,1110,308,1889,2204,19,359,1061,543,1234,1632,1846,68,545,597,713,982,2547,2205,1157,1903,1120,1390,509,276,2559,2620,2213,87,1961,1652,660,553,661,2176,1545,1969,1864,1707,1084
-0.1180065861783075,-0.5924746168808616,-0.9440776667177786,-0.1180065861783075,-0.17512221304650355,-1.6840786597335329,-0.06148029559266701,0.02222921008355008,1.5762892971839588,-0.7177615370892623,0.5244829444562599,2.558767311500275,0.23937792178355133,2.9408710467958437,0.673901466516914,1.9760700997311131,0.6245521818790327,0.4481994586006217,0.2127025180887077,0.3447912610633156,1.4289490678170462,0.10467597056101892,-1.7218791207703874,1.386093528320324,1.638208714171853,0.07733177575208161,-0.350125356105606,0.23937792178355133,-0.6861725882485472,-0.32056824010222307,-0.5003402500028168,-0.5308810490428666,-0.350125356105606,-0.2328390217993925,-0.43976167580769304,-0.2328390217993925,-0.2328390217993925,-0.17512221304650355,-0.17512221304650355,-0.1180065861783075,4.123983608212495,0.10467597056101892,-0.5003402500028168,4.3359171716292355,1.8789142803170127,0.3447912610633156,-0.7495318851344548,0.890558218300318,-0.7177615370892623,-0.2619266677946719,0.15895673427969537,0.31862879037972053,-0.8136248100970255,0.39674143767950243,0.0498499651371408,0.8669105116207638,-0.4097204049195783,-0.6235310490678561,4.111237733873485,0.7712686001756313,0.07733177575208161,0.49917415125399284,-0.03343454335768025,-0.2619266677946719,-0.37984219227896826,2.293640144931326,0.49917415125399284,0.4481994586006217,0.3447912610633156,0.13188385952514886,-1.0776690173461208,-0.6235310490678561,0.02222921008355008,-0.4097204049195783,0.0498499651371408,-0.1180065861783075,0.5496741112974982,0.9841240598522195,-1.1115742979561345,-1.3905052682383434,-0.6235310490678561,2.0714733698385936,-0.43976167580769304,-0.2619266677946719,0.39674143767950243,0.49917415125399284,0.39674143767950243,-0.5924746168808616,-0.2039047156366997,-0.43976167580769304,-0.37984219227896826,-0.2911692129463672,0.07733177575208161
2,702
Lipid droplet
7
27
2.321432
0.020264
Q07065,Q8NBX0,O43760,Q01105,P48449,Q99720,Q9H6V9
Localization
GO Cellular component
msigdb_gocc
320,41,73,238,43,14,51
1928,73,1601,615,819,2586,1932,560,43,1831,1422,1832,1882,238,320,1846,333,41,637,777,1395,14,51,2451,1701,1596,1548
-0.43976167580769304,2.2389705497371217,-0.2619266677946719,0.4225314103597223,0.23937792178355133,-1.2492972789568666,-0.43976167580769304,0.473746678395286,2.827512784417395,-0.37984219227896826,-0.14649000038336524,-0.37984219227896826,-0.4097204049195783,1.0988376535312658,0.8431585826801586,-0.37984219227896826,0.8193015508006276,2.876397384907642,0.4225314103597223,0.2923398612170866,-0.1180065861783075,4.199796153109882,2.7283466065358986,-0.8784677570852006,-0.2911692129463672,-0.2328390217993925,-0.2039047156366997
2,702