dataset
string
id
string
question
string
choices
list
rationale
string
answer
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subject
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medmcqa
medmcqa_49494
All are features of Alagille syndrome, EXCEPT:
[ "Posterior embryotoxon", "Hepatocellular jaundice", "Peripheral pulmonary stenosis", "Butterfly veebrae" ]
Syndromic paucity of interlobular bile ducts (Alagille syndrome) is the most common form of familial intrahepatic cholestasis. Chronic cholestasis affects 95% of patients. Peripheral pulmonic stenosis is observed in approximately 90%. Veebral arch defects are seen (e.g., butterfly veebrae, hemiveebrae, and a decrease i...
B
null
medmcqa
medmcqa_21371
One of the following activities is not meditated through beta 2 adrenergic receptor
[ "Stimulation of lipolysis", "Increased hepatic gluconeogenesis", "Increased muscle gluconeogenesis", "Smooth muscle relaxation" ]
Beta-agonist produce smooth muscle relaxation, bronchodilation, vasodilatation and uterine stimulation through beta 2 receptors. Also, Beta 3 receptors are located on adipocytes, not beta 2 beta 1- hea From medical pharmacology Padmaja 4th edition page no 101,105
A
null
medmcqa
medmcqa_8029
DMPA is an injectible contraceptive given every -
[ "Three weeks", "Two months", "Three months", "Two years" ]
park's textbook of preventive and social medicine 23rd edition. *DMPA has been in use since 1960s.The standard dose is an I'M injection of 150 mg every 3 months.It gives protection from pregnancy in 99% of women for at least 3 months.
C
null
medmcqa
medmcqa_36932
Eleven years after undergoing right modified radical mastectomy, a 61-year-old woman develops raised red and purple nodules over the right arm. What is the most likely diagnosis?
[ "Lymphangitis", "Lymphedema", "Lymphangiosarcoma", "Hyperkeratosis" ]
Lymphangiosarcoma is a rare complication of long-standing lymphedema, most frequently described in a patient who has previously undergone radical mastectomy (Stewart-Treves syndrome). It usually presents as blue, red, or purple nodules with satellite lesions. Early metastasis, mainly to the lung, may develop if it is n...
C
null
medmcqa
medmcqa_12117
Wrong statement about SGLT (sodium-glucose linked transpoer)
[ "SGLT1 is present in the intestine and kidneys", "SGLT1 has low capacity and high affinity", "SGLT2 inhibitors worsen hea failure", "SGLT2 inhibitors produce weight loss" ]
SGLT2 inhibitors reduce hospitalisation for hea failure as demonstrated by multiple cardiovascular outcome trials of various SGLT2 inhibitors. They produce glycosuria and weight loss. SGLT2 is a high capacity low affinity transpoer in contrast to SGLT1. In kidneys, SGLT2 is present in the proximal pa of the tubules whi...
C
null
medmcqa
medmcqa_14277
"Lead time" is,
[ "Time between disease onset and first possible point of diagnosis", "Time between first possible point of diagnosis and usual time of diagnosis", "Time between disease onset and final critical diagnosis", "Time between disease onset and usual time of diagnosis" ]
null
B
null
medmcqa
medmcqa_7166
Spur cells and stomatocytes in the peripheral smear is suggestive of:
[ "Alcoholic hepatitis", "Chronic liver disease", "Chronic kidney disease", "Hemolytic uraemic syndrome" ]
A mild hypoproliferative anemia may develop in patients with chronic liver disease. The peripheral blood smear shows spur cells and stomatocytes from the accumulation of excess cholesterol in the membrane due to deficiency of lecithin-cholesterol acyltransferase. Reference: Harrisons Principles of Internal Medicine, 18...
B
null
medmcqa
medmcqa_51211
All are risk factor for postoperative pulmonary complications except ?
[ "ASA class 3 and 4 patients", "Longer surgeries >2 hr", "Upper Abdominal surgery", "Age > 60 years" ]
Risk factor for postoperative pulmonary complications: Patients >=60 years of age COPD Markedly reduced exercise tolerance and functional dependence Hea failure ASA class 3 and 4 Cigarette smoking Longer surgeries (>4 h), Ceain types of surgery Abdominal Thoracic Aoic aneurysm Head and neck Emergency surgery GA (compar...
B
null
medmcqa
medmcqa_15699
Which of the following is not a feature of rhinosporidiosis-
[ "Bleeding polyp", "Russel bodies are seen", "Oral dapsone is useful in treatment", "Excision with the knife is the treatment" ]
Because the polyps are vascular & friable, they bleed easily upon manipulation. Complete excision of mass is done with diathermy knife & cauterization of base. Dapsone is being tried for treating rhinosporidiosis but with limited success. Russel bodies are not seen in Rhinosporidiosis but are a diagnostic feature of Rh...
B
null
medmcqa
medmcqa_8381
Acetic acid staining of cervix shows the following, except:
[ "Squamous metaplasia", "Cervical carcinoma in situ", "Cervical polyp", "Cervical dysplasia" ]
Cervical polyp is a common benign tumor on the surface of the cervical canal which has tissues much like the smooth muscle cells seen in a fibroid. The polyp does not pick up active staining with aceti acid because it has mosty 'resting' cells Acetic acid used coagulate the proteins - make the area Acetowhite. Biopsy t...
C
null
medmcqa
medmcqa_30994
A 4 year old female patient complains of decayed teeth. Intra-oral examination reveals occlusal caries with 55. The laser which can be used in this patient?
[ "CO2", "HeNe", "Excimer", "Ho:YAG" ]
Lasers are used primarily for either soft tissue applications or hard tissue surface modification. They generally are not used for tooth preparations because they are inefficient and awkward for removing large amounts of enamel or dentin, and that process with a laser can generate intolerable amounts of heat. Therefore...
D
null
medmcqa
medmcqa_2266
In a certain population, there were 4050 births in the last one year. There were 50 still births. 50 infants died within 7 days whereas 150 died within the first 28 days. What is the neonatal mortality rate?
[ "62.5", "50", "12.5", "49.4" ]
null
B
null
medmcqa
medmcqa_34074
A 25-year-old male comes to his physician for a follow up visit with weakness of his right hand. Two months ago, he suffered a motor vehicle accident in which his right hand was affected. On examination, he is unable to flex the metacarpophalangeal joints of the ring and index fingers, and is unable to adduct the same ...
[ "Flexor digitorum profundus", "Palmar interossei", "Extensor digitorum", "Dorsal interossei" ]
Answer: b) Palmar interosseiMusclesNerve supplyFunctionFlexor digitorum profundusLateral half by median nerve (anterior interosseous nerve); medial half by ulnar nerve Flexes distal interphalangeal joints of the index, middle, ring, and little fingers; can also flex metacarpophalangeal joints of the same fingers and th...
B
null
medmcqa
medmcqa_20016
A four year old boy was admitted with a history of abdominal pain and fever for two months maculopapular rash for ten days, and dry cough, dyspnea and wheezing for three days. One examination liver and spleen were enlarged 4 cm and 3 cm respectively below the costal margins. His hemoglobin was 10.0 g/dl, platelet count...
[ "Biphenotypic acute leukemia (lymphoid and eosinophil lineage)Acute eosinophilic leukemia)", "Acute lymphoblastic leukemia with hypereosinophilic syndrome", "Acute myeloid leukemia with eosinophilia", "All" ]
Ans. is 'c' i.e., Acute lymphoblastic leukemia with hypereosinophilic syndrome The cytochemical features of the blast Myeloperoxidases negative Non specific esterase ---> negative Both myeloperoxidaes and nonspecific esterases are positive in cells of myeloid origin and are negative in cellsoflymphoid origin. Remember,...
C
null
medmcqa
medmcqa_19236
The study of human relationships and of human behavior for better understanding of the pattern of human life, is called:
[ "Anthropology", "Social Psychology", "Social epidemiology", "Sociology" ]
Sociology Sociology can be viewed from two angles: (a) First, it can be seen as the study of relationships between human beings, and how these relationships change or vary in different pas of the world and at different times. The unit of study can be a small group (e.g., family) consisting of parents and children, or t...
D
null
medmcqa
medmcqa_24907
A HIV patient with CD4 count of 160 cells/ul presented with fever, cough and shoness of breath for 3 weeks. Chest X ray is shown below. Based on the x ray findings silver staining of the bronchoalveolar lavage was done and shown below. What is drug of choice for the causative organism?
[ "Azithromycin", "Vancomycin", "Gentamycin", "Cotrimoxazole" ]
Chest X ray depicts bilateral widespread interstitial pneumonia and Gomori Methenamine silver staining shows cysts with crushed ping pong balls appearance and are present in aggregate of 2-8. This is characteristic of Pneumocystis Pneumonia which is typically seen in AIDS patient in which CD4 cell count is below 200cel...
D
null
medmcqa
medmcqa_14170
Which of the following is not a sphincter in the female urogenital tract -
[ "Pubovaginalis", "External urethral sphincter", "Internal urethral sphincter", "Bulbospongiosus" ]
Urogenital sphincters in Females -        Vaginal sphincters Bulbospongiosus Sphincter urethrovaginalis External urethral sphincter Pubovaginalis -        Urinary sphincters Compressor urethrae External urethral sphincter Sphincter urethrovaginalis Pubourethralis
C
null
medmcqa
medmcqa_25024
True about sample registration system are all except?
[ "It is same as census", "It is dual record system", "It provides reliable estimate of bih rate and death rate", "Independent retrospective half - yearly" ]
.
A
null
medmcqa
medmcqa_46602
A child is able to build a tower of 5 cubes . His developmental age is ______
[ "12 months", "15 months", "18 months", "24 months" ]
By 18 months the child is able to scribble and make a tower of 3 blocks and by 2 yrs he is able to make tower of 6 months Mnemonic 2 yr is 24 months during which child makes tower of 2 +4 blocks that is 6 blocks 3 yr is 36 months during which child makes tower of 3 + 6 blocks that is 9 blocks Ref : OP GHAI - ESSENTIAL ...
C
null
medmcqa
medmcqa_16934
Not an indication for cholecystectomy for gallstones disease
[ "Asymptomatic gallstones with DM", "Procelain gallbladder", "Asymptomatic with history of single attack of acute pancreatitis", "Symptomatic cholecystitis" ]
Indications of prophylactic Cholecystectomy Cardiac transplant recepients Lung transplant recipients Chronic TPN requirements Recepients of biliopancreatic diversion (bariatric patient) Children with hemoglobinopathy (sickle cell, thalassemia and spherocytosis) Asymptomatic gallstone >=3cm Stone associated with the pol...
A
null
medmcqa
medmcqa_27924
Most common cause of inseional tendonitis of tendoachilles is -
[ "Overuse", "Improper shoe wear", "Infections from the ankle joint", "Steroid injections" ]
ACHILLES TENDINITIS: Athletes, joggers and hikers often develop pain and swelling around the tendo Achillis, due to local irritation of the tendon sheath or the paratenon.Clinical features :The condition may come on gradually, or rapidly following a change in spoing activity (or a change of spos footwear). Less commonl...
A
null
medmcqa
medmcqa_15485
Staphylococcus can cause
[ "Pharyngitis", "Tuberculosis", "Migraine", "Dermatitis" ]
Staphylococcal infections are the most common bacterial infections and range from tril to fatal. The common pyogenic staphylococcal infections are: Skin and soft tissue infections: Folliculitis, furuncle, abscess, wound infections, carbuncle, impetigo, paronychia and less often cellulitis. 2. Musculoskeletal: Osteomyel...
A
null
medmcqa
medmcqa_11029
In which of the following condition is blood osmolality increased:
[ "Diarrhea", "SIADH", "Psychogenic polydipsia", "Cerebral toxoplasmosis" ]
Diarrhea = Loss of water leads to concentration in body SIADH = Dilutional hyponatremia Psychogenic Polydipsia = Dilutional condition Cerebral toxoplasmosis leads to SIADH which again result in dilution
A
null
medmcqa
medmcqa_44447
Human diseases are due to bad clouds was a pa of which theory?
[ "Supernatural causes", "\"Miasma\" theory", "Germ theory", "Epidemiological triad" ]
"Miasma" theory which postulated that human diseases are due to bad clouds which are more dense at lower altitudes and hence diseases are more common among people who live nearer to the eah or sea level Ref: Textbook on Public Health and Community Medicine pg: 17
B
null
medmcqa
medmcqa_26243
ORF stands for:
[ "Open reading frame", "Oncogene removing frequency", "Oil related fraction", "Open reduction fracture" ]
null
A
null
medmcqa
medmcqa_46279
Disease which shows changes in occurrence (of disease) over a long period of time: March 2013 (a, h)
[ "Cyclic trend", "Secular trend", "Seasonal trend", "Sho term fluctuations" ]
Ans. B i.e. Secular trend Time trends 1. Secular (long-term) trends: Graphing the annual cases or rate of a disease over a period of years (Decades or centuries) shows long-term or secular trends in the occurrence of the disease. We commonly use these trends to suggest or predict the future incidence of a disease. Secu...
B
null
medmcqa
medmcqa_13883
Earliest presentation of Friedrich's ataxia is -
[ "Ataxia", "Seizures", "Optic atrophy", "Stuttering" ]
null
A
null
medmcqa
medmcqa_42939
Follicles of 0.5 mm size are typically seen in
[ "Pharyngoconjunctival fever", "Trachoma", "Drug induced follicular conjunctivitis", "Ophthalmia neonatorum" ]
Ans. B. Trachoma. (Ref: Khurana 3rd Edition page 92.).To diagnose active trachoma (esp Trachomatous inflammation-follicular stage), at least >5 follicles each of >0.5 mm diameter must be present on the upper tarsal conjunctiva.TRACHOMA WHO CLASSIFICATIONTrachoma has always been an important blinding disease under consi...
B
null
medmcqa
medmcqa_53944
18 years old male hears voices discussing him in 3rd person has
[ "Obsession", "Depression", "Mania", "Schizophrenia" ]
Voices discussing the person in 3rd person (third person hallucination) is characteristic of schizophrenia.
D
null
medmcqa
medmcqa_50563
Best mode of contraception for a newly married lady with rheumatic hea disease :
[ "Oral pills", "Norplant", "IUCD", "Condom" ]
Ans. is d i.e Condom
D
null
medmcqa
medmcqa_18815
Carriers for Herpes simplex virus is: March 2009
[ "Man", "Monkey", "Both", "None" ]
Ans. A: Man Humans are the only natural hosts and the sources of infection are saliva, skin lesions or respiratory secretions. Asymptomatic carriers form the more impoant source of infection, especially in genital infection.
A
null
medmcqa
medmcqa_12307
In facial nerve injury, loss of lacrimation is due to involvement of
[ "Chorda tympani nerve", "Buccal nerve", "Greater superficial petrosal nerve", "Deep petrosal nerve" ]
Secretomotor fibres to lacrimal gland leave at geniculate ganglion greater superficial petrosal nerve Ref: Dhingra 6th edition Pg. 97
C
null
medmcqa
medmcqa_12930
Tolerance means?
[ "Increase effect of drug on same dose", "Decrease effect of drug on same dose", "Same effect on lesser doses", "None" ]
Ans. is 'b' i.e., Decrease effect of drug on same dose * Tolerance means same dose produces markedly diminished effect on continuous use, therefore increased doses are required to produce same effect.* It is seen in alcohol dependent syndrome 8c has been included in its diagnostic criteria.
B
null
medmcqa
medmcqa_41541
Grevious hu comes under section:
[ "319", "320", "324", "326" ]
320
B
null
medmcqa
medmcqa_52879
Among the many molecules of high-energy phosphate compounds formed as a result of the functioning of the citric acid cycle, one molecule is synthesized at the substrate level. In which of the following reactions does this occur?
[ "Citrate - a-ketoglutarate", "a-ketoglutarate - succinate", "Succinate - fumarate", "Fumarate - malate" ]
A molecule of guanosine triphosphate is synthesized from guanosine diphosphate and phosphate at the cost of hydrolyzing succinyl CoA to succinate and CoA. This constitutes substrate-level phosphorylation, and, in contrast to oxidative phosphorylation, this is the only reaction in the citric acid cycle that directly yie...
B
null
medmcqa
medmcqa_22521
OR is not required in which fracture:?
[ "Patella", "Outer 1/3 of radius", "Condyle of humerus", "Olecranon displaced" ]
B i.e. Outer 1/3rd of radius Treatment Plan of Fracture Head of Radius Undisplaced split Single large displaced Small, displaced non - Comminuted fracture 1 aicular (inner 2/3) aicular (outer 1/3.1) - Fracture dislocation * Immobilization in above elbow fragment fragment POP with cuff & collar sling. 1 1 Excision of ra...
B
null
medmcqa
medmcqa_38798
Tardy ulnar nerve palsy -
[ "Early onset", "Late onset", "Caused by shoulder dislocation", "None" ]
Ans. is 'b' i.e., Late onsetTardy ulnar nerve palsyo Tardy ulnar nerve palsy as a late complication of the lateral condylar physis is well known, especially after the development of cubitus valgus from malunion or nonunion. Due to cubitus valgus there is chronic stretching of ulnar nerve. However, you should keep in mi...
B
null
medmcqa
medmcqa_29988
Which of the following is detected in peripheral blood smear -a) Malariab) Toxoplasmac) Babesiad) Brucellae) Filaria
[ "acd", "bde", "cde", "abce" ]
Parasites detectable in blood smear Plasmodium spp in RBCs Toxoplasma- Tachyzoites Filarial microfilaria Trypanosoma spp.: Trypomastigotes Leishmania amastigotes in macrophages Babesia- in RBC
D
null
medmcqa
medmcqa_23165
Lignocaine is useful for the treatment of :
[ "Atrial fibrillation", "Paroxysmal supraventricular tachycardia", "Digitalis induced ventricular extrasystoles", "All of the above" ]
(Ref: KDT 6/e p502) Lignocaine is used only for the treatment of ventricular arrhythmias, it has no role in atrial arrhythmia.
C
null
medmcqa
medmcqa_43745
A 80 year old patient presents with a midline tumor of the lower jaw, involving the alveolar margin. He is edentulous. Rx of choice is:
[ "Hemi mandibulectomy", "Commando operation", "Segmental mandiblectomy", "Marginal mandibulectomy" ]
Segmental mandibulectomy recommended for alveolar lesions, tumors adherent to the mandible, or for radiographic evidence of bone involvement. Ref: Craniomaxillofacial Reconstructive and Corrective Bone Surgery: Principles of Internal Fixation By Alex M. Greenberg, Joachim Prein, 2002, page 411.
C
null
medmcqa
medmcqa_32406
A man was diagnosed to have myositis ossificans progressiva at the age of 20 years. He died five years later. What is the most probable cause of his death-
[ "Starvation and chest infection", "Myocarditis", "Hypercalcemia", "Hyperphosphatemia" ]
Ans is option 1.. Starvation and chest infection. Myositis ossificans progressiva It is a congenital condition characterized by the formation of masses of bone in the soft tissues with consequent progressive impairment of movement of the underlying joint or joints All joint motion is finally lost and the patient dies o...
A
null
medmcqa
medmcqa_34625
Diabetic retinopathy, most likely present with –
[ "IDDM with 2 years duration", "NIDDM with 2 years duration", "Juvenile diabetes", "Gestational diabetes" ]
"Vision - threatening retinopathy is rare in type 1 diabetic patients in the first 3-5 years of diabetes or before puberty. During the next two decades, nearly all type 1 diabetic patients develop retinopathy. Up to 21% of patients with type 2 DM have retinopathy at the time of first diagnosis of diabetes and most deve...
B
null
medmcqa
medmcqa_38041
A 35 - year old male who had chronic duodenal ulcer for the last six years presents with worsening of symtomps loss of periodicity of symptoms, pain on rising in the morning sense of epigastric bloating and post - prandial vomiting. The most likely cause of the worsening of his symptoms is the development of ?
[ "Posterior penetration", "Gastric outlet obstruction", "Carcinoma", "Pancreatitis" ]
Ans. is 'b' i.e., Gastric outlet obstruction
B
null
medmcqa
medmcqa_34979
Ergonomics is a discipline that deals with:-
[ "Human relationship in the specific context of production", "Study of working environment", "Study of the system of laws and institutions", "Fitting the job to the workers" ]
ERGONOMICS: Definition: Is the application of scientific information concerning objects, systems and environment for human use. Pre-placement examination: Fitting job to workers. Right man in Right job. Post-placement examination- Regular periodic examination: Annual - most occupational exposures. Every 2 months - Radi...
D
null
medmcqa
medmcqa_51345
A young child of 7 years age is seen with indurated ulcers, lymphadenopathy and fever. The likely treatment is:
[ "Symptomatic treatment", "Systemic antibiotics", "Excise the lesion", "I.v. Fluids" ]
null
A
null
medmcqa
medmcqa_30508
Bleuler's Critaria for Schzophrenia includes all except ?
[ "Ambivalence", "Loosening of association", "Automatism", "Inappropriate Affect" ]
C i.e. Automatism
C
null
medmcqa
medmcqa_52584
A paitent met an accident with a car and has been in `deep coma' for the last 15 days. The most suitable route for the administration of protein and calories is by
[ "Jejunostomy tube feeding", "Gagstrotomy tube feeding", "Nasogastric tube feeding", "Central venous hyperalimentation" ]
Unless the gastrointestinal tract is non-functional, its use for nutritional suppo is preferable to the use of either the central or a peripheral venous route. However, in a patient who is comatose either nasogastric feeding or feedings through a gastrostomy tube may lead to vomiting and aspiration. This problem can be...
A
null
medmcqa
medmcqa_31871
A 40 year old male patient is suffering from type II diabetes mellitus and hypertension. Which of the following antihypertensive drugs should not be used in such patients
[ "Lisinopril", "Hydrochlorthiazide", "Losartan", "Trandolopril" ]
null
B
null
medmcqa
medmcqa_5653
Bronchial mucosa secretes all except?
[ "Bombesin", "Calcitonin", "Serotonin", "Bradykinin" ]
Ans. (d) Bradykinin(Ref: Robbins 9th/pg 669-670)Bronchial mucosa contains neuroendocrine cells that have neurosecretory-type granules releasing: serotonin Q, calcitonin Q, and gastrin-releasing peptide (bombesin) Q
D
null
medmcqa
medmcqa_45276
Which of the following is not an immediate cause of death?
[ "Thromboembolism", "Shock", "Septicemia", "Ventricular fibrillation" ]
ANSWER: (C) SepticemiaREF: Harrisons 18:h edchapter 233, 270, http://en.wikipedia.org/wiki/SepsisApproximately 20-35% of patients with severe sepsis and 40-60% of patients with septic shock die within 30 days. Others die within the ensuing 6 monthsVentricular fibrillation can lead to sudden cardiac deathAcute hemmorrha...
C
null
medmcqa
medmcqa_53872
Loading dose is given for which of the following drug
[ "Diazepam", "Propranolol", "Chloroquine", "Aspirin" ]
Chloroquine is a drug having maximum Volume of Distribution (Vd >1300 L). This means it is mostly distributed in the tissues whereas the main site of its pharmacological action is RBCs. Therefore, it is given as a loading dose to attain steady state plasma concentration quickly. Chloroquine is a synthetic 4-aminoquinol...
C
null
medmcqa
medmcqa_41484
All are true about dumping syndrome except:
[ "Treatment consists of small meal at short interval", "PP1 is very useful in treatment", "Watery & carbohydrate rich food are precipitating factors", "May occur after gastrectomy or vagotomy and drainage operations" ]
Ans: B (PPI is...) Early and late dumping L & B 26th/1039-40Although considered together because the symptoms are similar, early and late dumping have different aetiologies. A common feature, however, is early rapid gastric emptying.Many patients have both early and late dumping.Early dumping L&B26th/1039# It consists ...
B
null
medmcqa
medmcqa_37006
Which of the following is the first to improve after surgery for GH producing adenoma?
[ "Impaired glucose tolerance", "Hypeension", "Cardiomegaly", "Soft tissue swelling" ]
Trans-sphenoidal surgery is the preferred primary treatment for management of micro and macro-adenomas leading to acromegaly. The first symptom to improve is Soft tissue Swelling. Soft tissue swelling manifests as increased Heel pad thickness, increased shoe and glove size, ring tightening, coarse facies and large fles...
D
null
medmcqa
medmcqa_47888
Drug implicated for prolongation of QT interval in a premature baby is -
[ "Domperidone", "Metoclopramide", "Cisapride", "Omeprazole" ]
Ans. is 'c' i.e., Cisapride Cisapride inhibits the delayed rectifying IC- channels in hea and can cause prolongation of QT interval. o Drugs inhibiting CYP3A4 enzyme can precipitate Torsaes DePointes, Caused by cisapride eg; clarithromycin, erythromycin, cyclosporine, fluconazole, itraconazole, ketoconazole, Nefazodone...
C
null
medmcqa
medmcqa_11110
Which of the following is single most impoant indicator of likilihoodness of progression of hepatitis to liver cirrhosis
[ "Etiology", "Associated serological findings", "Presence of bridging necrosis", "Presence of mallary hyaline" ]
etiology is tje single most impoant indicator of liklihoodness of progression of hepatitis to cirrhosis HARSH MOHAN SIXTH EDITION PAGE.604-612
A
null
medmcqa
medmcqa_52978
Which of the following is not supplied by secretomotor fibre of facial nerve?
[ "Lacrimal gland", "Parotid gland", "Submandibular gland", "Nasal glands" ]
General visceral efferent fibres of the facial nerve are preganglionic parasympathetic fibres that arise from lacrimatory and superior salivatory nuclei in the brainstem.They supply the secretomotor fibres to lacrimal, submandibular and sublingual glands. Secretomotor fibres to the parotid gland are the auriculotempora...
B
null
medmcqa
medmcqa_51303
Ondansetron acts by:
[ "Action on CTZ", "5-HT3 antagonism", "D1 and D2 receptor antagonism", "Increasing GIT motility" ]
Ondansetron blocks the depolarizing action of serotonin through 5-HT3 receptors on vagal afferents in the gut as well as in NTS and CTZ. It donot block dopamine receptors or ACH receptors.( ref KDT 6/e p646)
A
null
medmcqa
medmcqa_38298
Tzank smear is done for all except
[ "Varicella", "Herpes", "Pemphigus", "Psoriasis" ]
Tzanck smear is a bedside test. It enables cytodiagnosis in vesicular and bullous lesions to demonstrate acantholytic or multinucleated cells. Acantholytic cells are keratinocytes which are large round cells with a dark central nucleus and peripheral condensed pink cytoplasm. These cells may be singular or in groups an...
D
null
medmcqa
medmcqa_50713
A 7 month old infant presents with stridor since the tenth day of life. What is the Most likely cause ?
[ "Laryngotracheobronchitis", "Tracheosophageal fistula", "Laryngomalacia", "Eventration of the diaphragm" ]
Laryngomalacia (Laryngeal Stridor) Laryngomalacia (LAYR inn go mah LAY shah) is also called laryngeal stridor. It results from a weakness of pas of the voice box (larynx) that is present at bih. This condition can cause a high-pitched sound called stridor (STRI der). You may hear this sound when your child breathes in....
C
null
medmcqa
medmcqa_27799
Organism identified by interferons:
[ "Staphylococcus", "Leptospira", "Campylobactor", "M. tuberculosis" ]
Ans. is. 'd' i. e., M. tuberculosis
D
null
medmcqa
medmcqa_36332
Cobble stoning of intestine with string sign of lean tor is seen in:
[ "Crohn's disease", "Ulcerative colitis", "Ischemic colitis", "Amoebic colitis" ]
Ans. (a) Crohn's disease* Cobble stone mucosa is appearance of the intestinal mucosa in Crohn's disease to the endoscopist,. Cobblestoning refers to the uniform nodules-due to the sub-mucosal fibrosis.* String sign of Kantor is due to involvement of the terminal ileum in Crohn's disease.* It is caused by severe spasm d...
A
null
medmcqa
medmcqa_12505
Nonoligouric kidney failure occurs with administration of which of the following drug/s?
[ "Gentamycin", "Cisplatin", "Ifosfamide", "All the above" ]
Ans. is 'd' i.e., All the above * ARF with urine output > 600 ml/day is defined as non-oliguric renal failure-* Important drugs cousing non-oliguric renal failure are -i) Aminoglycosides (e.g. gentamycin)iv) Ifosfomideii) Amphotericin Bv) Radiocontrast agentsiii) Cisplatinvi) Cyclosporine
D
null
medmcqa
medmcqa_31372
Mutton fat keratic precipitates are seen in
[ "Granuloma uveitis", "Non granulomatous uveitis", "Choroiditis", "Posterior staphyloma" ]
Ans. (a) Granuloma uveitis
A
null
medmcqa
medmcqa_20941
Nerve supply of scalpa) Auriculotemporal nerveb) Zygomatic nervec) Occipital nerved) Infratrochlear nerve
[ "ab", "abc", "acd", "bcd" ]
Nerves of the scalp and superficial temporal region In Front of auricle Behind th auricle Sensory nerves Sensory nerves 1.  Supratrochlear branch of  the frontal (ophthalmic  division of trigeminal  nerve) 1. Posterior division of great auricular nerve (C2, C3) from cervical plexus 2.  Supra...
B
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medmcqa
medmcqa_45031
Samogyi effect is -
[ "Morning hyperglycemia due to insulin resistance", "Morning hyperglycemia due to large dose of exogenous insulin", "Morning hypoglycemia due to large dose of exogenous insulin", "Evening hypoglycemia due to insulin resistance" ]
Answer- B. Morning hyperglycemia due to large dose of exogenous insulinRebound hyperglycemia, results from excess xogenous insulin, which causes hypoglycemia overnight and stimulates the release to counter regulatory hormones that in turn increase blood glucose levels.
B
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medmcqa
medmcqa_21511
Which of the following drugs is used for Narcoanalysis?
[ "Atropine", "Phenobarbitone", "Scopolamine", "Pethidine" ]
For the purpose of investigation, the application of forensic medicine plays a vital role. Nacro analysis is one of the methods used for lie detection. Scopolamine is one of the drugs used in Narcoanalysis. The truth serum drugs used in narcoanalysis are : 1. Scopolamine 2. Sodium Pentathal 3. Sodium Amytal 4. Sodium S...
C
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medmcqa
medmcqa_10364
Which of the following is not done in W.P.W?
[ "Treadmill test", "Electrophysiological studies", "Oral beta blocker", "Procainamide" ]
C/I of treadmill test: 1) severe AS 2) DVT 3) Charcot's joint 4) WPW 5) MI in first 48 hours 6) Unstable angina during attack 7) Buerger's disease 8) Bilateral osteoahritis of knee
A
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medmcqa
medmcqa_54360
What is the type of Goldman tonometry?
[ "Applanation Tonometry", "Dynamic countour tonometry", "Rebound tonometry", "Impression tonometry" ]
Ans. is 'a' i.e., Applanation Tonometry Measurement of intraocular pressure (IOP)* Measurement of IOP is done byA) Manometry It is the only direct measure of IOP.B) TonometryIt is an indirect method of measurement of IOP. Following types of tonometers are therei) Indentation (impression) tonometerThese are the most com...
A
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medmcqa
medmcqa_22825
A 57-year-old boy has been diagnosed to have posterior superior retraction pocket cholesteatoma. All would constitute part of the management, except -
[ "Audiometry", "Mastoid exploration", "Tympanoplasty", "Myringoplasty" ]
Ans-DMyringoplasty consists of closing a 'central perforation' in the tympanic membrane in the 'tubotympanic type' or 'safe type' of chronic suppurative otitis media. It is not indicated in the unsafe or dangerous type of otitis media with posterosuperior attic perforation.The patient in question is a case of the dange...
D
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medmcqa
medmcqa_16679
Flap commonly used in breast reconstruction is-
[ "Serratus anterior", "TRAM", "Flap from arm", "Delto pectoral flap" ]
null
B
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medmcqa
medmcqa_10188
In which of the following condition, flat capnogram is NOT seen?
[ "Apnea", "Complete laryngospasm", "Foreign body obstructing the upper airway", "None of the above" ]
Capnography is a valuable monitor of the pulmonary, cardiovascular, and anesthetic breathing systems. Capnographs in common use rely on the absorption of infrared light by CO2. A value commonly repoed on the capnography device is the end-tidal CO2 (the maximum CO2 concentration at the end of each tidal breath, or ETCO2...
D
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medmcqa
medmcqa_24184
True about papilloma is all except:
[ "Solitary is more common in adults and most common presentation is change in voice", "Solitary type is more aggressive, prognosis is bad and malignant transformation is common", "Multiple type is more common in children and most common presentation is hoarse cry", "Early treatment leads to better results in m...
(b) Solitary type is more aggressive, prognosis is bad and malignant transformation is common(Ref. Cummings, 6th ed., 923)Solitary type which is more common in adults is less aggressive (no stridor) and malignant transformation is rare.Early treatment will prevent stridor and therefore better results in multiple type i...
B
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medmcqa
medmcqa_45172
In submandibular gland excision all of the following nerves may be affected except
[ "Lingual nerve", "Hypoglossal nerve", "Glossopharyngeal nerve", "Mandibular division of trigeminal nerve" ]
Ans. (c) Glossopharyngeal nerveRef: Bailey and Love 27th edition Page 780The following nerves are at risk during Submandibular surgery:2 Superficial nerves:* Marginal Mandibular branch of Facial nerve* Rarely Cervical Branch of Facial nerve* 2 Deep Cranial nerves:* Lingual Nerve* Hypoglossal nerve
C
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medmcqa
medmcqa_39755
Glucose transpoer in myocyte stimulated by insulin in-
[ "a) GLUT-1", "b) GLUT-2", "c) GLUT-3", "d) GLUT-4" ]
GLUT- 4 is present in Hea, skeletal muscle, adipose tissue.
D
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medmcqa
medmcqa_13467
Treatment of choice for carcinoma LarynxT1 NOMO stage:
[ "External beam radiotherapy", "Radioactive implants", "Surgery", "Surgery and radiotherapy" ]
Treatment for stage I of cancer larynx (glottic cancer) is either microlaryngoscopic surgery or Radiotherapy. External Bean Radiation or Brachytherapy External bean radiation is most often used to treat laryngeal and hypopharyngeal cancer. Brachytherapy is rarely used to treat laryngeal or hypopharyngeal cancer. Radiat...
A
null
medmcqa
medmcqa_33833
For diatoms test, the best site for taking a sample is -
[ "Lungs", "Bone marrow in Ulna", "Bone marrow in femur", "Muscle" ]
Diatoms can be demonstrated in all the given options. "The current technique for isolation of diatoms involve acid digestion of tissue-commonly bone marrow, lung, blood or kidneys with subsequent centrifugation and washing." - Parikh "Bone marrow of long bone (e.g. femur) is examined for diatoms. Kidney, lung, liver o...
C
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medmcqa
medmcqa_53203
Most accurate treatment for erectile dysfunction is
[ "Sildenafil", "Master and Johnson technique", "Beta blockers", "Papaverine" ]
Sildenafil citrate has been used for the treatment of erectile dysfunction. Rapidly absorbed after oral administration, the maximum plasma concentration is reached in 30-120 minutes. It is metabolised in liver (mainly by cytochrome P450 3A4) and is conveed to an active metabolite. Sildenafil has a terminal half-life of...
A
null
medmcqa
medmcqa_30175
True statement regarding ileum is -
[ "Tongue shaped villi in the lumen", "Lymphatic patch along antimesenteric border", "Supplied by inferior mesenteric vessels", "Joins caecum at anterior surface" ]
Lymphatic patches (peyer's patches) are placed lengthwise along the antimesenteric border of the intestine. Vili in ileum is finger-like. The ileum is a midgut derivative and is therefore supplied by the superior mesenteric artery. Ileum joins the caecum on posterior-medial aspect of coecum.
B
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medmcqa
medmcqa_54162
A 27-year-old woman complains of double vision and fatigue at the end of the day. Further history reveals difficulty in chewing food, and some weakness in climbing stairs. She has stopped running because of easy leg fatigue and leg weakness. The symptoms improve with resting. On examination, there is weakness of the ey...
[ "hypercalcemia", "myasthenia gravis", "multiple sclerosis", "thyroid storm" ]
The most common presenting symptoms relate to weakness of eye muscles, causing ptosis or diplopia. Difficulty in chewing, dysarthria, and dysphagia are also common. The differential diagnosis includes all diseases that cause weakness of oropharyngeal or limb muscles. These include the muscular dystrophies, ALS, and pro...
B
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medmcqa
medmcqa_50223
In Kwashiorkor, which immunoglobulin is most affected -
[ "IgD", "lgA", "IgE", "IgM" ]
Ans. is 'b' i.e., IgA In malnourished subjects, secretory IgA is generally reduced. Therefore infections tend to be severe and recovery delayed.
B
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medmcqa
medmcqa_38222
Which of the following is coding RNA
[ "sn RNA", "mRNA", "Both sn RNA and mRNA", "mi RNA" ]
rRNA, Lnc RNA, sn RNA, mi RNA, tRNA are all non coding RNA. Only mRNA is coding RNA.
B
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medmcqa
medmcqa_36834
Regarding prion which of the following statements is true?
[ "It is protein product coded in viral DNA", "It catalyzes abnormal folding of other protein", "It protects disulfide bond from oxidation", "It cleaves normal proteins" ]
Ans. is 'b' i.e., It catalyzes abnormal folding of other protein Prions are small protein-containing infectious particles with no detectable nucleic acid. They were suspected to be viruses but otherwise do not conform to the standard definition of viruses. They differ from the viruses in their many properties. The prio...
B
null
medmcqa
medmcqa_43126
Which one of the tissues putrefies late
[ "Brain", "Prostate", "Liver", "Stomach" ]
B i.e. Prostate
B
null
medmcqa
medmcqa_14078
A newborn presents with an early onset of dyspnea with chest retractions, expiratory grunting and cyanosis following an uneventful normal preterm labor. On examination no cardiac murmurs are heard and the lungs appear clear. On a plain X-ray there is evidence of prominent pulmonary vascular markings and fluid lines in ...
[ "Meconium aspiration syndrome", "Fetal aspiration syndrome", "Transient tachypnea of the newborn", "Hyaline membrane disease" ]
Transient tachypnea of the newborn * The clinical case given above indicates the likely diagnosis of transient tachynea of the newborn, which is otherwise called Respiratory distress syndrome type II. * It is characterized by the early onset of dyspnea with chest retractions, expiratory grunting and cyanosis. Neonates ...
C
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medmcqa
medmcqa_51948
Features of Binder's syndrome:
[ "Maxillonasal dysplasia", "Class 3 profile", "Hypoplasia of nasal septum and premaxilla", "All of the above" ]
Binder’s Syndrome Maxillo - nasal dysplasia Hypoplasia of nasal septum & premaxilla Absent ANS Class 3 profile
D
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medmcqa
medmcqa_18406
Medical adrenalectomy can be done by: September 2012
[ "Vincristine", "Vinblastine", "Mitotane", "Methotrexate" ]
Ans. C i.e. Mitotane
C
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medmcqa
medmcqa_19768
A 65-year-old man worked in a shipyard for 10 years, and then he worked for 5 years for a company that installed fire retardant insulation. He experienced increasing dyspnea for 11 years with progressive respiratory failure and hypoxemia. A CT scan of his chest now shows a large mass encasing the left lung. Which of th...
[ "Bilateral fluffy perihilar infiltrates", "Bilateral upper lobe cavitation", "Diaphragmatic pleural calcified plaques", "Endobronchial mass with atelectasis" ]
This patient has an occupational risk of asbestos exposure. The inhaled asbestos fibers become encrusted with iron and appear as the characteristic ferruginous bodies with iron stain. The firm, tan mass encasing the pleura is most likely a malignant mesothelioma. Asbestosis more commonly gives rise to pleural fibrosis ...
C
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medmcqa
medmcqa_29079
All are associated with malignancy except :
[ "Down's syndrome", "Fragile X syndrome", "Bloom syndrome", "Fanconi's anaemia" ]
Has been explained (see factors predisposing to childhood leukemia).
B
null
medmcqa
medmcqa_6710
In Fracture acetabulum, late complication is -
[ "Osteoarthritis", "Tardy sciatic nerve palsy", "Recurrent Dislocation", "None of the above" ]
In the longer term, the common problem is the development of hip osteoarthritis. Other possible problems include AVN of femoral head and heterotopic ossification (bone formation).
A
null
medmcqa
medmcqa_29937
Type II Mirizzi's syndrome
[ "Obstruction of common duct by external compression only(no erosion)", "Erosion of one-thirds circumference of common duct", "Erosion of upto two-third circumference of common duct", "Total /near total circumferential of common duct" ]
Classification of Mirizzi's Syndrome (Csendes classification) Type I Obstruction of common duct by external compression only(no erosion) Type II Erosion of less than one-third circumference of common duct Type III Erosion of upto two-third circumference of common duct Type IV Total/near total circumferential destructio...
B
null
medmcqa
medmcqa_40741
Lower 1/3 of vagina is formed by
[ "Mesonephric duct", "Paramesonephric duct", "Sinovaginal bulb", "Mesoderm of mullerian duct" ]
Lower 2/3rd of vagina formed from sinovaginal bulb which comes from endoderm of urogenital sinus. Upper 1/3rd of vagina is derived from fused paramesonephric duct. Mesonephric duct forms the collecting pa or ductular pa of male reproductive system. Mesoderm of Mullerian duct is basically paramesonephric duct.
C
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medmcqa
medmcqa_36657
Tigroid white matter on MR spectroscopy seen in:-
[ "Pantothenate kinase deficiency", "Pelizaeus-merzbacher disease", "Neuroferritinopathy", "Aceruloplasminemia" ]
Ans. (b) Pelizaeus-merzbacher diseaseRef: Harrisons Principle of Internal Medicine 20th Ed; Page No- 3049* The Tigroid pattern or stripe sign is also known as leopard skin sign results from dark-spots or stripes (spared perivascular white matter) within bright demyelinated periventricular white matter on T2W images.* I...
B
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medmcqa
medmcqa_6454
10 year old boy complaints of pain in right arm near the shoulder, x-ray shows expansile lytic lesion in upper third of humerus, what is the likely diagnosis.
[ "Aneurysmal Bone cyst", "Simple bone cyst", "Giant cell tumor", "Osteosarcoma" ]
null
B
null
medmcqa
medmcqa_17632
Which of the following vessels is involved in extradural haematoma?
[ "Middle meningeal artery", "Venous sinuses", "Bridging veins", "Middle cerebral artery" ]
Ans. a (Middle meningeal artery). (Ref: B & L, Surgery, 25th/ 303).Extradural haematoma (EDH)# It is a neurosurgical emergency. An EDH is nearly always associated with a skull fracture and is more common in young male patients. The skull fracture is asso- ciated with tearing of a meningeal artery and a haematoma accumu...
A
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medmcqa
medmcqa_16619
Delirium is distinguished from dementia by the presence of:
[ "Impaired judgment", "Impaired memory", "Clouding of consciousness", "Thought disorder" ]
The hallmark of delirium is fluctuation in level of consciousness. Periods of lucency may be interspersed with periods of marked unresponsiveness. Another distinguishing feature is that the onset of delirium usually occurs within hours or days, whereas the onset of dementia may be insidious throughout a period of weeks...
C
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medmcqa
medmcqa_25673
Tinel's sign is positive in
[ "Peripheral nerve regeneration", "Tendon injury", "Tenosynovitis", "Rheumatoid arthritis" ]
(A) Peripheral nerve regeneration # Tinel s sign: Tinel's sign is elicited as follows:> Tap the injured nerve along its course starting peripherally.> The point at which the patient feels tingling sensation along the course of the nerve indicates that recovery has started and has reached that point.> Also seen in compa...
A
null
medmcqa
medmcqa_51172
Emmetropia is associated with
[ "Myopia", "Astigmatism", "Hypermetropia", "Absence of refractive error" ]
Emmetropia (optically normal eye) is a state of refraction when the parallel rays of light coming from infinity are focused at the sensitive layer of the retina with accommodation at rest. At bih, the eyeball is relatively sho and thus most infants are born with +2 to +3 D hypermetropia. This is gradually reduced and b...
D
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medmcqa
medmcqa_41729
Double-Bubble" sign in X-ray is seen in:
[ "Colon carcinoma", "Duodenal atresia", "Acute pancreatitis", "Perforation" ]
Duodenal atresia
B
null
medmcqa
medmcqa_6005
Reticulocytosis is seen in all except:
[ "P.N.H", "Hemolysis", "Nutritional anemia", "Dyserythropoietic syndrome" ]
Answer is both C and D (Nutritional Anemia and Congenital dyserythropoeitic anemia) Nutritional anemia is associated with normal/Low Retriculocyte count. Increased reticulocyte count (Reticulocytosis) is not a feature ,,f nutritional anemias. Nutritional Anemia Anemia resulting from deficiency of impoant nutrients in d...
D
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medmcqa
medmcqa_21751
Amount of fat is maximum in which milk:
[ "Cow", "Buffalo", "Human", "Goat" ]
Amount per 100 ml Cow's milk Human milk Buffalo milk Goat milk Fat 4.1 g 3.4 g 6.5 g 4.5 g Protein 3.3 g 1.1 g 4.3 g 3.3 g Lactose 4.4 g 7.4 g 5.1 g 4.6 g Ref: Park, 22nd edition pg: 584
B
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