Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Invasion of minor veins of tobacco leaves inoculated with tobacco mosaic virus mutants defective in phloem-dependent movement. | To fully understand vascular transport of plant viruses, the viral and host proteins, their structures and functions, and the specific vascular cells in which these factors function must be determined. We report here on the ability of various cDNA-derived coat protein (CP) mutants of tobacco mosaic virus (TMV) to invad... | ['Capsid', 'Genes, Viral', 'Immunohistochemistry', 'Mutagenesis', 'Plant Diseases', 'Plants, Toxic', 'Tobacco', 'Tobacco Mosaic Virus', 'Viral Structural Proteins'] | 8,855,325 | [['A21.249.500.250'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512',... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Liver transplantation in hepatocellular carcinoma: new developments]. | Today, liver transplantation is the only simultaneous treatment of cirrhosis as well as of HCC. A crucial factor for outcome after liver transplantation is the appropriate selection of patients. Tumor diameter and node number in correlation with the histopathological grading are used as surrogate markers to predict the... | ['Carcinoma, Hepatocellular', 'Humans', 'Liver Neoplasms', 'Liver Transplantation', 'Lymphatic Metastasis', 'Neoplasm Staging', 'Prognosis', 'Survival Rate'] | 12,233,282 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.7... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of Laryngeal Mask Airway Supreme and Laryngeal Mask Airway Proseal with respect to oropharyngeal leak pressure during laparoscopic cholecystectomy: a randomised controlled trial. | CONTEXT: A comparison of the efficacy and safety of the Laryngeal Mask Airway (LMA) Supreme (LMAS) versus the LMA Proseal (LMAP) in elective laparoscopic cholecystectomy.OBJECTIVES: To compare the LMAS with LMAP in terms of ventilatory efficacy, airway leak pressure (airway protection), ease-of-use and complications.DE... | ['Adult', 'Aged', 'Anesthesia, General', 'Anesthesiology', 'Cholecystectomy, Laparoscopic', 'Equipment Design', 'Female', 'Humans', 'Intubation, Intratracheal', 'Laryngeal Masks', 'Male', 'Middle Aged', 'Pressure', 'Prospective Studies', 'Single-Blind Method', 'Tidal Volume', 'Treatment Outcome'] | 23,318,811 | [['M01.060.116'], ['M01.060.116.100'], ['E03.155.197'], ['H02.403.066'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E02.041.500.475', 'E02.585.578.475', 'E05.497.578.475', 'E07.700.500.450', 'J01.637.708.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Racial disparity in stroke risk factors: the Berlin-Ibadan experience; a retrospective study. | BACKGROUND: Different workers have reported racial disparities in the distribution of risk factors for stroke and stroke subtype (ischemic vs hemorrhagic). No transcultural transnational studies have been conducted to confirm and relate these disparities to one another. Our objective was to identify differences in the ... | ['Adult', 'African Continental Ancestry Group', 'Aged', 'Aged, 80 and over', 'Atherosclerosis', 'Berlin', 'Cerebral Infarction', 'Demography', 'Dyslipidemias', 'European Continental Ancestry Group', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Nigeria', 'Pilot Projects', 'Retrospective Studies', 'Risk Fa... | 18,638,038 | [['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126.307'], ['Z01.433.128', 'Z01.542.315.182'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Selective brain hypothermia suppresses noxious-evoked movement in canines. | Systemic hypothermia suppresses noxious-evoked movement, but its main site of action is unknown. We examined the effect of hypothermia in the brain on noxious-evoked movement by selectively cooling the brain. Sixteen beagles were randomly divided into two groups and anesthetized with isoflurane/oxygen. After being deep... | ['Animals', 'Blood Pressure', 'Body Temperature', 'Brain', 'Dogs', 'Electroencephalography', 'Female', 'Hypothermia, Induced', 'Movement', 'Pain'] | 15,845,705 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.374', 'G07.110'], ['A08.186.211'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.376.300', 'E01.370.405.245'], ['E02.258.750'], ['G07.568', 'G11.427.410'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder. | Manic-depressive (bipolar) illness is a serious psychiatric disorder with a strong genetic predisposition. The disorder is likely to be multifactorial and etiologically complex, and the causes of genetic susceptibility have been difficult to unveil. Lithium therapy is a widely used pharmacological treatment of manic-de... | ['Base Sequence', 'Bipolar Disorder', 'Chromosome Mapping', 'Chromosomes, Human, Pair 18', 'Chromosomes, Human, Pair 8', 'DNA Primers', 'Humans', 'Norway', 'Phosphoric Monoester Hydrolases', 'Polymorphism, Single Nucleotide', 'Promoter Regions, Genetic'] | 14,699,425 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['F03.084.500'], ['E05.393.183'], ['A11.284.187.520.300.415.430', 'G05.360.162.520.300.415.430'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.649.313.988.400.112.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Effects of barium concentration on the radiopacity and biomechanics of bone cement: experimental study. | PURPOSE: This study was undertaken to evaluate the changes in the radiopacity and mechanics of polymethylmethacrylate (PMMA) bone cement with the addition of barium.MATERIALS AND METHODS: Barium sulfate powder was added to a PMMA bone cement with an initial 10% barium concentration. The changes in radiopacity and stren... | ['Barium Sulfate', 'Biomechanical Phenomena', 'Bone Cements', 'Compressive Strength', 'Image Processing, Computer-Assisted', 'Materials Testing', 'Polymethyl Methacrylate', 'Radiographic Image Enhancement', 'Stress, Mechanical', 'Tensile Strength', 'Tomography Scanners, X-Ray Computed'] | 19,030,961 | [['D01.103.075', 'D01.875.800.800.850.075'], ['G01.154.090', 'G01.374.089'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['G01.374.180'], ['L01.224.308'], ['E05.570'], ['D02.241.081.069.800.550.500', 'D05.750.716.822.111.650.605.500', 'D25.720.716.822.111.650.605.50... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Some results for an SEIR epidemic model with density dependence in the death rate. | This paper deals with an SEIR epidemic model for an infectious disease where the death rate depends on the number of individuals in the population. It is also assumed that there is an additional death rate suffered by infected individuals. It is found that there are three steady-state values: one where the population i... | ['Animals', 'Communicable Diseases', 'Disease Outbreaks', 'Humans', 'Mathematics', 'Models, Biological', 'Mortality', 'Population Density'] | 1,517,675 | [['B01.050'], ['C01.221', 'C23.550.291.531'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['E05.599.395'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['N01.224.600', 'N06.850.505.400.600']] | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Adult rhabdomyoma of the extremity. | Adult rhabdomyoma is a rare benign tumor. It mainly occurs in the head and neck region and rarely occurs outside the head and neck region. We present an extremely rare case of the adult rhabdomyoma arising in the left foot in a 46-year-old male. Microscopically, large polygonal cells and large strap-shaped cells were o... | ['Foot Diseases', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Rhabdomyoma'] | 24,021,898 | [['C05.360', 'C17.800.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['C04.557.450.590.540.700']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relationship between photosensitizing activities and chemical structure of hypocrellin A and B. | Hypocrellins A (HA) and B (HB) are two main pigments isolated from the parasitic fungi Hypocrella bambusae (B. et Br) Sacc. and Shiraia bambusicola P. Heen found in China. These pigments have a long history as traditional medicinal agents. Although HA and HB have the same perylene quinonoid structure, there are differe... | ['Cyclic N-Oxides', 'Drugs, Chinese Herbal', 'Electron Spin Resonance Spectroscopy', 'Free Radicals', 'Light', 'Oxygen', 'Perylene', 'Phenol', 'Quinones', 'Radiation-Sensitizing Agents', 'Spin Labels', 'Structure-Activity Relationship'] | 1,331,387 | [['D03.661.243'], ['D20.215.784.500.350', 'D26.335'], ['E05.196.867.519.274'], ['D01.339', 'D02.389'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D01.268.185.550', 'D01.362.670'], ['D02.455.426.559.847.149.700', 'D02.455.426.559.847.680.500', 'D04.615.149.700', 'D04.615.680.500'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adenosarcoma of the uterus: ultrastructural observations. | M?llerian adenosarcoma has been recently described as a distinctive biphasic uterine tumor with benign epithelial and malignant stromal components. The lesion belongs generally to the group of mixed m?llerian tumors, but the benignity of the epithelium separates it from the other neoplasms of this type. This entity usu... | ['Aged', 'Female', 'Humans', 'Microscopy, Electron', 'Uterine Neoplasms', 'Wilms Tumor'] | 217,264 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['C04.588.945.418.948', 'C13.351.500.852.762', 'C13.351.937.418.875'], ['C04.557.435.595', 'C04.588.945.947.535.585', 'C04.700.900', 'C12.758.820.750.585', 'C12.777.419.473.585', 'C13.351.937.820.535.585', 'C1... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Erythropoietin ameliorates diabetes-associated cognitive dysfunction in vitro and in vivo. | Several studies indicate that erythropoietin (EPO) has remarkable neuroprotective effects in various central nervous system disorders, while little is known about the effects of EPO in diabetes-associated cognitive dysfunction. Therefore, the present study aimed to investigate whether EPO ameliorates diabetes-associate... | ['Animals', 'Apoptosis', 'Cell Survival', 'Cognitive Dysfunction', 'Diabetes Complications', 'Diabetes Mellitus, Experimental', 'Disease Models, Animal', 'Erythropoietin', 'Glucose', 'Glycogen Synthase Kinase 3 beta', 'Models, Biological', 'Neuroprotective Agents', 'Oxidative Stress', 'PC12 Cells', 'Phosphatidylinosito... | 28,584,284 | [['B01.050'], ['G04.146.954.035'], ['G04.346'], ['F03.615.250.700'], ['C19.246.099'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['D09.947.875.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mortality in patients with Crohn's disease. | BACKGROUND: No data on mortality for Crohn's disease are available from southern Europe.METHODS: Five hundred and thirty-one patients with Crohn's disease were observed in our unit between 1973 and 1993. In 325 patients the first diagnosis was made in our hospital. In this consecutive incidence series, in which the fol... | ['Adolescent', 'Adult', 'Aged', 'Cause of Death', 'Child', 'Crohn Disease', 'Europe', 'Female', 'Humans', 'Male', 'Middle Aged', 'Survival Rate'] | 8,726,306 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.060.406'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Changes in the transaldolase activity in the liver, spleen and bone marrow of rats after total X-ray irradiation]. | The paper deals with changes in the activity of transaldolase in tissues of the liver, spleen and bone marrow of rats 4.24 h and on the 3 d, 7th, 18th, 30th, 45th, and 60th day after total X-ray irradiation in a dose of 600 R. The ionizing irradiation causes a stable inhibition of the enzyme activity in All tissues. Th... | ['Animals', 'Bone Marrow', 'Kinetics', 'Liver', 'Male', 'Rats', 'Spleen', 'Transaldolase', 'Transferases', 'Whole-Body Irradiation'] | 7,036,489 | [['B01.050'], ['A15.382.216'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['A10.549.700', 'A15.382.520.604.700'], ['D08.811.913.200.650'], ['D08.811.913'], ['E02.815.814', 'E05.980']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development and testing of the autobiographical memory coding tool. | Development and testing of the autobiographical memory coding tool (AMCT) is detailed. The tool uses quantitative content analysis procedures to code interpretations of autobiographical memories as validating or lamenting. Development of a system of measuring autobiographical memories from transcribed reminiscence inte... | ['Abstracting and Indexing', 'Aged', 'Aged, 80 and over', 'Autobiographies as Topic', 'Choice Behavior', 'Female', 'Geriatric Nursing', 'Grief', 'Happiness', 'Humans', 'Life Change Events', 'Male', 'Nursing Methodology Research', 'Personal Satisfaction', 'Reproducibility of Results', 'Self Concept', 'Social Support'] | 8,496,515 | [['L01.453.245.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['K01.517.211.215'], ['F02.463.785.373.346'], ['H02.478.676.236', 'N02.421.533.245'], ['F01.470.142.110'], ['F01.470.516'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['H01.770.644.145.390.634', 'H02.478.395.634', 'N04.590.23... | ['Information Science [L]', 'Named Groups [M]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Children's adjustment and prosocial behaviour in step-, single-parent, and non-stepfamily settings: findings from a community study. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood. | The adjustment and prosocial behaviour of 4-year-old children and their older siblings growing up in step-parent or single-parent families, or with two biological parents, was investigated within a longitudinal community study, the Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC). Mean differences in mothers... | ['Adolescent', 'Adult', 'Child', 'Child Behavior Disorders', 'Child, Preschool', 'Family', 'Family Characteristics', 'Family Relations', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Parent-Child Relations', 'Parents', 'Regression Analysis', 'Sampling Studies', 'Sex Characteristics', 'Single Parent', 'Social Adj... | 9,844,979 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['F03.625.141'], ['M01.060.406.448'], ['F01.829.263', 'I01.880.853.150'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[An unusual case of cystic nephroma protruding into the renal pelvis]. | Cystic nephroma is a relatively rare and benign renal lesion of uncertain etiology. Approximately 200 cases have been described, but only a few cases of cystic nephroma with prominent renal pelvis involvement have been reported. Here, we report an unusual case of cystic nephroma that protruded into the renal pelvis. A ... | ['Female', 'Humans', 'Kidney Diseases, Cystic', 'Kidney Pelvis', 'Middle Aged'] | 21,063,163 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.403', 'C13.351.968.419.403'], ['A05.810.453.537'], ['M01.060.116.630']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase. | A series of experiments has been carried out to characterize 58-kDa human neutrophil collagenase (HNC) and compare it with human fibroblast collagenase (HFC). N-Terminal sequencing of latent and spontaneously activated HNC shows that it is a distinct collagenase that is homologous to HFC and other members of the matrix... | ['Amino Acid Sequence', 'Blotting, Western', 'Cross Reactions', 'Fibroblasts', 'Glycoproteins', 'Humans', 'Microbial Collagenase', 'Molecular Sequence Data', 'Molecular Weight', 'Neutrophils', 'Protein Processing, Post-Translational', 'Substrate Specificity'] | 2,176,876 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G12.122.281'], ['A11.329.228'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480.205.500', 'D08.811.277.656.675.37... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[7-alpha-Hydroxylation of 5 alpha-androstane-3 beta, 17 beta-diol in human normal and hyperplastic prostates]. | Incubation of 4-14C-5 alpha-androstane-3 beta, 17 beta-diol with human normal and hyperplastic prostate minces led to the NADPH-dependent production of a major polar radiometabolite which was identified as 5 alpha-androstane-3 beta, 7 alpha, 17 beta-triol and proved the presence of a 3 beta-hydroxysteroid-7 alpha-hydro... | ['Adolescent', 'Androstane-3,17-diol', 'Androstanes', 'Humans', 'Male', 'Prostate', 'Prostatic Hyperplasia', 'Steroid Hydroxylases'] | 71,955 | [['M01.060.057'], ['D04.210.500.054.040.080', 'D06.472.334.851.968.500'], ['D04.210.500.054'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.444.575', 'A10.336.707'], ['C12.294.565.500'], ['D08.244.453.915', 'D08.811.682.690.708.170.915', 'D12.776.422.220.453.915']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Consecutive melatonin circadian rhythms in normal volunteers. | Circadian plasma melatonin secretion patterns were determined in 12 healthy men over 3 consecutive 24-hour periods. The rhythms showed marked intra-individual stability, but pronounced interindividual variation. Plasma melatonin may serve as a reliable biological marker. Plasma melatonin assayed between 23h00 and 01h00... | ['Adult', 'Circadian Rhythm', 'Humans', 'Light', 'Male', 'Melatonin', 'Reference Values'] | 2,919,339 | [['M01.060.116'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D03.633.100.473.914.481', 'D06.472.506'], ['E05.978.810']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Design, synthesis, and evaluation of hydroxamic acid derivatives as promising agents for the management of Chagas disease. | Today, there are approximately 8 million cases of Chagas disease in the southern cone of South America alone, and about 100 million people are living with the risk of becoming infected. The present pharmacotherapy is sometimes ineffective and has serious side effects. Here, we report a series of 4,5-dihydroisoxazoles i... | ['Animals', 'Carbonic Anhydrase Inhibitors', 'Carbonic Anhydrases', 'Cell Line, Tumor', 'Chagas Disease', 'Drug Design', 'Humans', 'Hydroxamic Acids', 'Isoenzymes', 'Isoxazoles', 'Macrophages, Peritoneal', 'Mice', 'Mice, Inbred BALB C', 'Peptide Hydrolases', 'Protease Inhibitors', 'Structure-Activity Relationship', 'Tr... | 24,299,463 | [['B01.050'], ['D27.505.519.389.200'], ['D08.811.520.241.300.150'], ['A11.251.210.190', 'A11.251.860.180'], ['C01.610.752.300.900.200', 'C01.920.625'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.570.394', 'D02.241.511.372'], ['D08.811.34... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Biotypes and ScM types of isolates of Streptococcus canis | Lancefield group G Streptococcus canis is a component of the normal urogenital and pharyngeal flora of the cat. It is also frequently implicated in epizootics of severe disease in closed cat colonies and animal shelters. Given the importance of S canis as a feline pathogen and relative lack of published information on ... | ['Animals', 'Bacterial Typing Techniques', 'Cat Diseases', 'Cats', 'Streptococcal Infections', 'Streptococcus'] | 28,077,757 | [['B01.050'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C01.150.252.410.890'], ['B03.353.750.737.872', 'B03.510.400.800.872', 'B03.510.550.737.872']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of trypan blue staining on the density and viability of lens epithelial cells in white cataract. | PURPOSE: To assess the effect of anterior capsule staining with trypan blue 0.0125% on the density and viability of the lens epithelial cells (LECs).SETTING: Iladevi Cataract and IOL Research Center, Ahmedabad, India.METHODS: This randomized prospective study comprised 40 eyes having phacoemulsification for white matur... | ['Capsulorhexis', 'Cataract', 'Cell Count', 'Cell Survival', 'Coloring Agents', 'Epithelial Cells', 'Female', 'Humans', 'Lens Capsule, Crystalline', 'Lens, Crystalline', 'Male', 'Middle Aged', 'Phacoemulsification', 'Prospective Studies', 'Staining and Labeling', 'Trypan Blue'] | 16,931,259 | [['E04.540.825.249.352'], ['C11.510.245'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.346'], ['D27.720.233'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.500.155'], ['A09.371.060.500'], ['M01.060.116.630'], ['E04.540.825.249.704', 'E04.943.875'], ['E05.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adaptation of a trap door technique for the recovery of ovarian cortical biopsies from Cebus apella (capuchin monkey). | There is a paucity of efficient cryopreservation protocols for primordial follicles enclosed in the ovarian tissue from non-human primates (NHP), in special New World primates. Our objective was to establish an optimal procedure for the recovery of ovarian biopsies from capuchin monkeys. To this end, we adapted a trap ... | ['Animals', 'Biopsy', 'Cebus', 'Female', 'Humans', 'Microscopy', 'Ovarian Follicle', 'Reconstructive Surgical Procedures', 'Ultrasonography, Doppler, Duplex'] | 22,475,413 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.600.150.170.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['A05.360.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Particle bombardment-mediated transient expression of a Brazil nut methionine-rich albumin in bean (Phaseolus vulgaris L.). | Bean (Phaseolus vulgaris L.) mature embryos were transformed using biolistic methods with a plasmid containing 2S albumin and beta-glucuronidase structural sequences, both under the control of the 35S CaMV promoter. We have shown that chimaeric tissues could be obtained and that both structural sequences were expressed... | ['2S Albumins, Plant', 'Antigens, Plant', 'Blotting, Western', 'Cloning, Molecular', 'Electrophoresis, Polyacrylamide Gel', 'Fabaceae', 'Nuts', 'Plant Proteins', 'Plants, Medicinal', 'Recombinant Fusion Proteins'] | 1,391,783 | [['D12.776.765.725.249'], ['D23.050.291'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.393.220'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.650.940.800.575.912.250.401'], ['A18.024.500.500', 'G07.203.300.700', 'J02.500.700'], ['D12.776.765'], ['B01.650.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Analysis of factors affecting failure of glass cermet tunnel restorations in a multi-center study. | The aim of this study was to analyze factors influencing the failures of tunnel restorations performed with a glass cermet cement (Ketac Silver). Caries activity, lesion size, tunnel cavity opening size, partial or total tunnel, composite lamination or operating time showed no significant correlation to failure rate. T... | ['Adolescent', 'Adult', 'Bicuspid', 'Cermet Cements', 'Child', 'Composite Resins', 'Dental Caries', 'Dental Caries Susceptibility', 'Dental Cavity Preparation', 'Dental Restoration Failure', 'Dental Restoration, Permanent', 'Dentin', 'Female', 'Follow-Up Studies', 'Humans', 'Logistic Models', 'Male', 'Molar', 'Radiogra... | 11,480,816 | [['M01.060.057'], ['M01.060.116'], ['A14.549.167.860.150'], ['D01.552.033.690.250', 'D25.058.520.250', 'D25.339.208.720.250', 'D25.339.291.402.120', 'J01.637.051.058.520.250', 'J01.637.051.339.208.720.250', 'J01.637.051.339.291.402.120'], ['M01.060.406'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308'... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
The boron-neutron capture agent beta-D-5-o-carboranyl-2'-deoxyuridine accumulates preferentially in dividing brain tumor cells. | Boron-neutron capture therapy (BNCT) is based on the preferential targeting of tumor cells with (10)B and subsequent irradiation with epithermal neutrons to produce a highly localized field of lethal alpha particles, while sparing neighboring non-targeted cells. BNCT treatment of 9L brain tumors in a rat model using be... | ['Boron Neutron Capture Therapy', 'Brain Neoplasms', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Chromatography, High Pressure Liquid', 'Deoxyuridine', 'Flow Cytometry', 'Glioma', 'Humans', 'Radiation-Sensitizing Agents'] | 16,132,519 | [['E02.815.722.500.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['E05.196.181.400.300'], ['D03.383.742.680.852.300', 'D13.570.230.430', 'D13.570.685.852.300'], ['E01.370.225.500.363.342', 'E01.370.225.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Body burdens of mercury, lead, selenium and copper among Baltimore newborns. | Umbilical cord blood or serum concentrations of mercury, lead, selenium and copper were measured with inductively coupled plasma mass spectrometry in a population of 300 infants born in Baltimore, Maryland. Geometric mean values were 1.37 ìg/L (95% confidence interval: 1.27, 1.48) for mercury; 0.66 ìg/dL (95% CI: 0.61,... | ['Adolescent', 'Adult', 'Baltimore', 'Body Burden', 'Copper', 'Cross-Sectional Studies', 'Fatty Acids, Omega-3', 'Female', 'Fetal Blood', 'Humans', 'Infant, Newborn', 'Lead', 'Maternal Exposure', 'Mercury', 'Pregnancy', 'Selenium', 'Socioeconomic Factors', 'Statistics, Nonparametric', 'Urban Population', 'Young Adult'] | 21,277,575 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['E05.799.638.231', 'N06.850.460.200'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Fruit flies (Diptera, Tephritidae) and their associations with native host plants in a remnant area of the highly endangered Atlantic Rain Forest in the State of Esp?rito Santo, Brazil. | The results presented in this paper refer to a host survey, lasting approximately three and a half years (February 2003-July 2006), undertaken in the Vale do Rio Doce Natural Reserve, a remnant area of the highly endangered Atlantic Rain Forest located in Linhares County, State of Esp?rito Santo, Brazil. A total of 330... | ['Animals', 'Biological Evolution', 'Brazil', 'Conservation of Natural Resources', 'Feeding Behavior', 'Fruit', 'Tephritidae', 'Tropical Climate'] | 18,439,337 | [['B01.050'], ['G05.045', 'G16.075'], ['Z01.107.757.176'], ['J01.256', 'N06.230.080'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.050.500.131.617.720.500.500.750.850'], ['G16.500.275.071.600', 'N06.230.300.100.250.600']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Identifying dynamic functional connectivity biomarkers using GIG-ICA: Application to schizophrenia, schizoaffective disorder, and psychotic bipolar disorder. | Functional magnetic resonance imaging (fMRI) studies have shown altered brain dynamic functional connectivity (DFC) in mental disorders. Here, we aim to explore DFC across a spectrum of symptomatically-related disorders including bipolar disorder with psychosis (BPP), schizoaffective disorder (SAD), and schizophrenia (... | ['Adult', 'Bipolar Disorder', 'Brain', 'Brain Mapping', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Nonlinear Dynamics', 'Oxygen', 'Principal Component Analysis', 'Psychotic Disorders', 'Schizophrenia', 'Time Factors', 'Young Adult'] | 28,294,459 | [['M01.060.116'], ['F03.084.500'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.599.850', 'H01.548.675'], ['D01.268.185.550', 'D01.362.670'], ['E05.318.740... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
The Impact of Plasmacytoid Variant Histology on the Survival of Patients with Urothelial Carcinoma of Bladder after Radical Cystectomy. | BACKGROUND: The clinical significance of the plasmacytoid variant (PCV) in urothelial carcinoma (UC) is currently lacking.OBJECTIVE: To compare clinical outcomes of patients with any PCV with that of patients with pure UC treated with radical cystectomy (RC).DESIGN, SETTING, AND PARTICIPANTS: We identified 98 patients ... | ['Aged', 'Carcinoma, Transitional Cell', 'Cystectomy', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Retrospective Studies', 'Survival Rate', 'Treatment Outcome', 'Urinary Bladder Neoplasms'] | 28,753,857 | [['M01.060.116.100'], ['C04.557.470.200.430'], ['E04.950.774.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.599.8... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
SSWAP: A Simple Semantic Web Architecture and Protocol for semantic web services. | BACKGROUND: SSWAP (Simple Semantic Web Architecture and Protocol; pronounced "swap") is an architecture, protocol, and platform for using reasoning to semantically integrate heterogeneous disparate data and services on the web. SSWAP was developed as a hybrid semantic web services technology to overcome limitations fou... | ['Computational Biology', 'Databases, Factual', 'Information Dissemination', 'Information Storage and Retrieval', 'Internet', 'Semantics', 'Software', 'User-Computer Interface'] | 19,775,460 | [['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['L01.143.443'], ['L01.313.500.750.280', 'L01.470'], ['L01.224.230.110.500'], ['L01.559.598.745'], ['L01.224.900'], ['L01.224.900.910']] | ['Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Hydrazone- and hydrazide-containing N-substituted glycines as peptoid surrogates for expedited library synthesis: application to the preparation of Tsg101-directed HIV-1 budding antagonists. | Replacing the Pro6 in the p6(Gag)-derived 9-mer "P-E-P-T-A-P-P-E-E" with N-substituted glycine (NSG) residues is problematic. However, incorporation of hydrazone amides ("peptoid hydrazones") can be readily achieved in library fashion. Furthermore, reduction of these hydrazones to N-substituted "peptoid hydrazides" aff... | ['Amino Acid Sequence', 'Anti-HIV Agents', 'DNA-Binding Proteins', 'Endosomal Sorting Complexes Required for Transport', 'Glycine', 'HIV-1', 'Hydrazines', 'Hydrazones', 'Oligopeptides', 'Peptide Library', 'Peptoids', 'Proline', 'Transcription Factors'] | 17,048,869 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.954.122.388.077.088'], ['D12.776.260'], ['D05.500.199', 'D12.776.543.990.493'], ['D12.125.481'], ['B04.820.650.589.650.350.400'], ['D02.442'], ['D02.442.288'], ['D12.644.456'], ['D12.644.555', 'G02.111.570.060.620', 'G05.360.325.640'], ['D12.644.679'], ['D12.125.07... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An oral administration of a recombinant anti-TNF fusion protein is biologically active in the gut promoting regulatory T cells: Results of a phase I clinical trial using a novel oral anti-TNF alpha-based therapy. | BACKGROUND: An orally administered BY-2 plant cell-expressed recombinant anti-TNF fusion protein (PRX-106) consists of the soluble form of the human TNF receptor (TNFR) fused to the Fc component of a human IgG1 domain. Aim This study aim at determining the safety and the immune modulatory effect of an oral administrati... | ['Administration, Oral', 'Adolescent', 'Adult', 'Cytokines', 'Etanercept', 'Humans', 'Immunomodulation', 'Immunotherapy', 'Inflammatory Bowel Diseases', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'T-Lymphocytes, Regulatory', 'Tumor Necrosis Factor-alpha', 'Young Adult'] | 28,392,436 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.644.541.500.697.624', 'D12.776.124.486.485.538.500.624', 'D12.776.124.486.485.680.697.624', 'D12.776.124.790.651.538.500.624', 'D12.776.124.790.651.680.660.624', 'D12.776.377.715.548.538.500.624', 'D12.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Photothermal studies of CO photodissociation from mixed valence Escherichia coli cytochrome bo3. | Here, we report the volume and enthalpy changes accompanying CO photodissociation from the mixed valence form of cytochrome bo3 oxidase from Escherichia coli. The results of photoacoustic calorimetry indicate two kinetic phases with distinct volume and enthalpy changes accompanying CO photodissociation from heme o3 and... | ['Carbon Monoxide', 'Cytochrome b Group', 'Cytochromes', 'Escherichia coli', 'Escherichia coli Proteins', 'Kinetics', 'Ligands', 'Molecular Conformation', 'Oxidation-Reduction', 'Photolysis', 'Spectroscopy, Fourier Transform Infrared', 'Temperature', 'Thermodynamics'] | 15,896,790 | [['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['D08.244.187', 'D12.776.422.220.187'], ['D08.244', 'D12.776.422.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['G02.111.570.820'], ['G02.700', 'G03.295.531'], ['G02.740.685'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pre-procedural bioimpedance vectorial analysis of fluid status and prediction of contrast-induced acute kidney injury. | OBJECTIVES: The aim of this study was to evaluate the relationship between pre-procedural fluid status assessed by bioimpedance vector analysis (BIVA) and development of contrast-induced acute kidney injury (CI-AKI).BACKGROUND: Accurate fluid management in patients undergoing angiographic procedures is of critical impo... | ['Acute Kidney Injury', 'Aged', 'Cohort Studies', 'Contrast Media', 'Coronary Angiography', 'Coronary Artery Disease', 'Electric Impedance', 'Female', 'Humans', 'Hydrodynamics', 'Male', 'Middle Aged', 'Odds Ratio', 'Retrospective Studies', 'Triiodobenzoic Acids', 'Water-Electrolyte Imbalance'] | 24,530,668 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro reendothelialization. Microfilament bundle reorganization in migrating porcine endothelial cells. | An experimentally induced wound made in a confluent monolayer culture of porcine thoracic aortic endothelial cells (ECs) was studied 22 hours after wounding using 7-nitrobenz-2-oxa-1,3-diazole (NBD) phallacidin and immunofluorescence microscopy to localize actin and myosin containing microfilament (MF) bundles. ECs ext... | ['Actins', 'Amanitins', 'Animals', 'Aorta, Thoracic', 'Cell Movement', 'Cytoskeleton', 'Endothelium', 'Fluorescent Antibody Technique', 'Myosins', 'Swine', 'Time Factors', 'Wound Healing'] | 6,367,729 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D04.345.566.050', 'D12.644.456.050', 'D12.644.641.050', 'D23.946.587.175'], ['B01.050'], ['A07.015.114.056.372'], ['G04.198', 'G07.568.500.180'], ['A11.284.430.214.190.750'], ['A10.272.491'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Craniofacial augmentation with porous polyethylene implants (Medpor: first clinical results]. | SUBJECT: Porous polyethylene (Medpor) is an alloplastic material commonly used in craniofacial reconstruction. We report about our first clinical experiences with Medpor for facial augmentation procedures.PATIENTS AND METHODS: We treated 27 patients between 2001 and 2005 (11 female, 16 male) with 48 Medpor-implants. Th... | ['Adolescent', 'Adult', 'Biocompatible Materials', 'Bone Screws', 'Child', 'Craniofacial Abnormalities', 'Device Removal', 'Esthetics', 'Facial Injuries', 'Facial Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Polyethylenes', 'Prostheses and Implants', 'Prosthesis Design', 'Prosthesis-Related Infections'... | 16,685,567 | [['M01.060.057'], ['M01.060.116'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['M01.060.406'], ['C05.660.207', 'C16.131.621.207'], ['E04.199'], ['F02.463.785.477', 'K01.752.210'], ['C10.900.300.284', 'C26.915.300.425'], ['C04.588.443.392... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Negative and helpful statements in a patient only or therapist guided internet forum in the aftercare for psychosomatic inpatients. | BACKGROUND: The aftercare of patients in the wake of inpatient treatment is a therapeutic challenge. Aim of the present study was to investigate the utilization, and positive or negative interactions in a patient only (PF) and a therapist guided internet forum (TF) in the follow up of psychosomatic inpatient treatment.... | ['Adult', 'Aftercare', 'Female', 'Helping Behavior', 'Humans', 'Internet', 'Male', 'Middle Aged', 'Patient Discharge', 'Pessimism', 'Physician-Patient Relations', 'Psychophysiologic Disorders', 'Psychotherapy, Group', 'Self Care', 'Therapy, Computer-Assisted'] | 29,197,201 | [['M01.060.116'], ['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['F01.145.813.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['M01.060.116.630'], ['E02.760.169.125', 'E02.760.400.610', 'N02.421.585.169.125', 'N02.421.585.400.610', 'N04.590.233.727.210.125'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Simultaneous patellar tendon avulsion fracture from both patella and tibial tuberosity: a case report. | We present a simultaneous patella tendon avulsion fracture from both sides of its attachment in an ectopic ossified patellar tendon. Medially two thirds of the patellar tendon was detached from the inferior patella, and laterally one third of that from anterior tibial tuberosity with the patellar tendon split. Osteosyn... | ['Aged', 'Humans', 'Knee Injuries', 'Male', 'Orthopedic Procedures', 'Ossification, Heterotopic', 'Patellar Ligament', 'Radiography'] | 16,897,070 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['E02.718', 'E04.555'], ['C23.550.751'], ['A02.513.514.475', 'A02.835.583.512.475', 'A02.880.438', 'A10.165.669.514.475'], ['E01.370.350.700']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Angiogenesis and vascular endothelial growth factor-/receptor expression in myeloproliferative neoplasms: correlation with clinical parameters and JAK2-V617F mutational status. | Data on angiogenesis in the bone marrow of BCR-ABL1-negative myeloproliferative neoplasm (MPN) patients suggest an increase of the microvessel density (MVD) and vascular endothelial growth factor (VEGF) expression, but relations to the JAK2-V617F status remain controversial. We performed immunohistochemical studies of ... | ['Bone Marrow', 'Case-Control Studies', 'Female', 'Humans', 'Immunohistochemistry', 'Janus Kinase 2', 'Male', 'Microvessels', 'Middle Aged', 'Mutation', 'Myeloproliferative Disorders', 'Neovascularization, Pathologic', 'Receptors, Vascular Endothelial Growth Factor', 'Vascular Endothelial Growth Factor A'] | 19,466,975 | [['A15.382.216'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Laboratory reactivity models as predictors of ambulatory blood pressure and heart rate. | We attempted to validate the usefulness of the laboratory reactivity paradigm by examining responses to three distinct lab tasks and an overall lab average as predictors for ambulatory blood pressure. Subjects were 126 university students. We assessed ambulatory blood pressure, heart rate and perceived distress during ... | ['Adolescent', 'Adult', 'Blood Pressure', 'Blood Pressure Determination', 'Female', 'Heart Rate', 'Humans', 'Laboratories', 'Male', 'Monitoring, Physiologic', 'Sex Factors', 'Stress, Psychological', 'Task Performance and Analysis'] | 8,027,961 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J03.520', 'N02.278.487'], ['E01.370.520'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.126.990', 'F0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Surgery for diverticulitis in renal failure. | Twenty-five patients were operated on at the Brigham and Women's Hospital for colonic diverticulitis complicating treated renal failure during the period 1951 to 1983. Twelve patients had functioning renal allografts (eight cadaver, four living-related); 13 were on dialysis therapy. Six patients had polycystic kidney d... | ['Aging', 'Diverticulitis, Colonic', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Renal Dialysis', 'Retrospective Studies', 'Time Factors'] | 3,902,414 | [['G07.345.124'], ['C06.405.205.282.500.250', 'C06.405.469.158.587.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.060.116.630'], ['C23.550.767'], ['E02.870.300', 'E02.912.800'], ['E05.318.37... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Daclatasvir plus asunaprevir for HCV genotype 1b infection in patients with or without compensated cirrhosis: a pooled analysis. | BACKGROUND & AIMS: We compared outcomes by cirrhosis status across studies of the all-oral combination of daclatasvir (DCV) plus asunaprevir (ASV).METHODS: Outcomes from global and Japanese phase 2 and 3 clinical studies of DCV+ASV in patients with genotype (GT) 1b infection were assessed by cirrhosis status. Sustained... | ['Alanine Transaminase', 'Antiviral Agents', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Imidazoles', 'International Cooperation', 'Isoquinolines', 'Liver', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Sulfonamides', 'Sustained Virologic Respons... | 26,683,763 | [['D08.811.913.477.700.100'], ['D27.505.954.122.388'], ['E02.319.283'], ['E02.319.310'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The relationship between basketball shooting kinematics, distance and playing position. | Three-dimensional cinematography (100 Hz) was used to establish the relationship between distance and the kinematics of shooting with respect to playing position in basketball. Fifteen subjects, divided into guards, forwards and centres (all n = 5), performed jump shots from each of three distances: 2.74, 4.57 and 6.40... | ['Adult', 'Analysis of Variance', 'Basketball', 'Biomechanical Phenomena', 'Humans', 'Kinetics', 'Male', 'Sports'] | 8,809,716 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['I03.450.642.845.117'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['I03.450.642.845']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Socioeconomic inequalities in mental well-being among Hungarian adolescents: a cross-sectional study. | INTRODUCTION: According to several empirical studies, mental well-being is significant in adolescence; adolescent's social network is undergoing radical changes while at the same time depression is increasing. The primary goal of our study is to determine whether socioeconomic status (SES) is associated with mental hea... | ['Adolescent', 'Female', 'Health Status Disparities', 'Humans', 'Hungary', 'Male', 'Mental Health', 'Psychology, Adolescent', 'Social Class', 'Social Determinants of Health', 'Surveys and Questionnaires'] | 25,348,821 | [['M01.060.057'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['F02.418', 'N01.400.500'], ['F04.096.628.065'], ['I01.880.853.996.755', 'N01.824.782'], ['N01.224.425.762', 'N01.400.675'], ['E05.318.308.980', 'N05.715.360.300.800... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Basal and stress-induced adrenocortical activity in young pigeons during pre- and post-hatching periods (author's transl)]. | The functioning of the hypothalamic pituitary-adrenocortical system was tested in young pigeons before and after hatching, by radiocompetitive assay of plasma corticosterone (B) at rest and under stress. 1 degree B was expressed in ng/ml. Resting adult values (8-10) could not be observed before the birds were 6 week-ol... | ['Animals', 'Columbidae', 'Corticosterone', 'Female', 'Male', 'Pituitary-Adrenal System', 'Stress, Physiological'] | 7,411,484 | [['B01.050'], ['B01.050.150.900.248.165.150'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['A06.300.691'], ['G07.775']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exercise training and myocardial remodeling in patients with reduced ventricular function: one-year follow-up with magnetic resonance imaging. | BACKGROUND: Exercise training is now an accepted therapeutic intervention in patients with reduced ventricular function after a myocardial infarction. However, there are conflicting reports on the effects of training on the remodeling process of the heart, and previous studies have only assessed short-term effects of t... | ['Exercise Test', 'Exercise Therapy', 'Follow-Up Studies', 'Hemodynamics', 'Humans', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardium', 'Randomized Controlled Trials as Topic', 'Treatment Outcome'] | 10,650,298 | [['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.510'], ['M01.0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evidence for a deployment-related Gulf War syndrome by factor analysis. | To identify a syndrome unique to Gulf War veterans, the authors applied an exploratory factor analysis to the 47-symptom correlation matrix of 10,423 Gulf War and 8,960 non-Gulf War veteran respondents. A separate factor analysis was performed for Gulf War and non-Gulf War veterans, and the resulting 6 factors were com... | ['Adult', 'Chi-Square Distribution', 'Factor Analysis, Statistical', 'Female', 'Health Surveys', 'Humans', 'Male', 'Military Medicine', 'Nervous System Diseases', 'Persian Gulf Syndrome', 'Surveys and Questionnaires', 'Veterans'] | 12,071,362 | [['M01.060.116'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Optimized preparation of vinpocetine proliposomes by a novel method and in vivo evaluation of its pharmacokinetics in New Zealand rabbits. | Free-flowing proliposomes which contained vinpocetine were prepared successfully to increase the oral bioavailability of vinpocetine. In this study the proliposomes were prepared by a novel method which was reported for the first time and the formulation was optimized using the centre composite design (CCD). The optimi... | ['Administration, Oral', 'Animals', 'Area Under Curve', 'Biological Availability', 'Drug Carriers', 'Drug Delivery Systems', 'Drug Evaluation, Preclinical', 'Drug Stability', 'Liposomes', 'Male', 'Nootropic Agents', 'Particle Size', 'Rabbits', 'Technology, Pharmaceutical', 'Temperature', 'Time Factors', 'Vinca Alkaloid... | 19,651,165 | [['E02.319.267.100'], ['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['G03.787.151', 'G07.690.725.129'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['E05.290.750', 'E05.337.550'], ['E05.916.330'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.08... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Patient-level Predictors of Extent of Exposure to a Community Health Worker Intervention in a Randomized Controlled Trial. | Objective: Community health worker (CHW) interventions have been cited as a best practice for reducing health disparities, but patient-level attributes may contribute to differential uptake. We examined patient characteristics associated with the extent of exposure to a CHW coaching intervention among a predominantly l... | ['Adult', 'African Americans', 'Baltimore', 'Community Health Workers', 'Female', 'Health Education', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Minority Health', 'Poverty'] | 31,057,311 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['M01.526.485.067.080', 'N02.360.067.080'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['N01.400.512'], ['I01.880.735.634', 'I01.8... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Metastatic involvement of parotid from carcinoma of the breast--a case report. | INTRODUCTION: Involvement of parotid gland by metastases from distant primary malignant tumors is rare.CASE REPORT: A 42-year-old female having right breast cancer had reported to the Department of Oral Diagnosis and Medicine with a chief complaint of a swelling in the left parotid gland region for 2 months. On the bas... | ['Adult', 'Biopsy', 'Breast', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Diagnosis, Differential', 'Female', 'Humans', 'India', 'Neck Dissection', 'Parotid Gland', 'Parotid Neoplasms'] | 19,190,940 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['E01.17... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Lactoferrin works as a new LPS-binding protein in inflammatory activation of macrophages. | Though lactoferrin (LF) is a glycoprotein that is involved in immunomodulation, its action mechanism has not been fully elucidated. Previous studies have suggested that lipopolysaccharide (LPS) activity is inhibited by direct binding between LPS and LF. However, here we show that when LPS and purified LF was mixed, and... | ['Acute-Phase Proteins', 'Animals', 'Blotting, Western', 'Carrier Proteins', 'Cells, Cultured', 'Electrophoretic Mobility Shift Assay', 'Immunoassay', 'Inflammation', 'Lactoferrin', 'Lipopolysaccharides', 'Macrophage Activation', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred C3H', 'NF-kappa B', 'Nitrites', 'Receptors... | 15,251,114 | [['D12.776.124.050'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.157'], ['A11.251'], ['E05.196.401.500'], ['E05.478.566', 'E05.601.470'], ['C23.550.470'], ['D08.811.277.656.300.760.471', 'D08.811.277.656.959.350.471', 'D12.776.157.427.750.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Choosing the best needle for diagnostic lumbar puncture. | A new generation of Atraumatic (blunt tipped) needles now exists in addition to the traditional Quincke (cutting tip) needles for LP. We wished to identify the optimal size and type of needle that should be used for this technique. Requirements include rapid and accurate transduction of CSF pressure and adequate flow r... | ['Humans', 'Needles', 'Spinal Puncture'] | 8,710,120 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.612'], ['E01.370.225.998.054.790', 'E01.370.376.700', 'E02.800.779', 'E04.074.790', 'E04.665.700', 'E05.200.998.054.790']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feature-specific terrain park-injury rates and risk factors in snowboarders: a case-control study. | BACKGROUND: Snowboarding is a popular albeit risky sport and terrain park (TP) injuries are more severe than regular slope injuries. TPs contain man-made features that facilitate aerial manoeuvres. The objectives of this study were to determine overall and feature-specific injury rates and the potential risk factors fo... | ['Adolescent', 'Adult', 'Alberta', 'Case-Control Studies', 'Child', 'Female', 'Humans', 'Incidence', 'Injury Severity Score', 'Male', 'Risk Factors', 'Skiing'] | 24,184,587 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.567.176.064'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], [... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Phase II study of denileukin diftitox for relapsed/refractory B-Cell non-Hodgkin's lymphoma. | PURPOSE: Denileukin diftitox is a fusion protein combining diphtheria toxin and interleukin-2 (IL-2) that targets tumor cells expressing the IL-2 receptor. Its efficacy has been shown in CD25+ cutaneous T-cell lymphoma, but not in B-cell non-Hodgkin's lymphoma (NHL). A phase II study was performed to evaluate the effic... | ['Adult', 'Aged', 'Antineoplastic Agents', 'CD4 Antigens', 'CD8 Antigens', 'Diphtheria Toxin', 'Disease-Free Survival', 'Drug Administration Schedule', 'Female', 'Humans', 'Hypoalbuminemia', 'Interleukin-2', 'Lymphoma, B-Cell', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Receptors, Interleukin-2', 'Recombinan... | 15,353,540 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['D23.050.301.264.894.108', 'D23.101.100.894.108'], ['D08.811.913.400.725.115.220', 'D23.946.123.305'], ['E01.789.800.190', 'E05.318.740.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cloning and sequencing of the genes encoding the light-harvesting B806-866 polypeptides and initial studies on the transcriptional organization of puf2B, puf2A and puf2C in Chloroflexus aurantiacus. | The genes encoding the alpha- and beta-polypeptide subunits of the B806-866 membrane-bound light-harvesting complex of Chloroflexus aurantiacus have been cloned and the nucleotide sequences determined. The gene puf2A, which encodes the B806-866 alpha-polypeptide, began 28 bases downstream of the stop codon of puf2B, wh... | ['Amino Acid Sequence', 'Bacteria', 'Bacterial Proteins', 'Base Sequence', 'Cloning, Molecular', 'Cytochrome c Group', 'Genes, Bacterial', 'Molecular Sequence Data', 'Photosynthetic Reaction Center Complex Proteins', 'Pigments, Biological', 'RNA, Bacterial', 'RNA, Messenger', 'Sequence Analysis, DNA', 'Sequence Homolog... | 7,535,995 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D08.244.286', 'D12.776.422.220.286'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['L01.453.245.667'], ['D05.500.562.488', 'D08.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Determination of the secondary structure of Kluyveromyces lactis beta-galactosidase by circular dichroism and its structure-activity relationship as a function of the pH. | The secondary structure of Kluyveromyces lactis beta-galactosidase was determined by circular dichroism. It is mainly a beta-type protein, having 22% beta-turns, 14% parallel beta-sheet, 25% antiparallel beta-sheet, 34% unordered structure, and only 5% alpha-helix. The structure-activity relationship as a function of t... | ['Chromatography, Gel', 'Circular Dichroism', 'Electrophoresis, Polyacrylamide Gel', 'Fungal Proteins', 'Hydrogen-Ion Concentration', 'Kluyveromyces', 'Lactase', 'Protein Conformation', 'Structure-Activity Relationship', 'beta-Galactosidase'] | 16,366,715 | [['E05.196.181.400.250'], ['E05.196.867.151'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.354'], ['G02.300'], ['B01.300.107.795.536', 'B01.300.930.536'], ['D08.811.277.450.410.100.500'], ['G02.111.570.820.709'], ['G02.111.830', 'G07.690.773.997'], ['D08.811.277.450.410.100']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glucocorticoid-induced alternative promoter usage for a novel 5' variant of granzyme A. | Glucocorticoids exert diverse physiological functions through transcriptional regulation of genes including granzyme A (GZMA). GZMA is one of the apoptotic effectors localized in cytotoxic T lymphocytes and is considered to mediate glucocorticoid-induced apoptosis of human leukemia 697 cells. In the present study, we i... | ["5' Untranslated Regions", 'Alternative Splicing', 'Base Sequence', 'Chromatin Immunoprecipitation', 'Dexamethasone', 'Gene Expression Regulation', 'Genetic Variation', 'Granzymes', 'Humans', 'Introns', 'Luciferases', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Receptors, Glucocorticoid', 'Regulatory Sequ... | 17,180,578 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.170', 'E05.478.605.160'], ['D04.210.500.745.432.769.344', 'D0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intravenous feeding in a gastroenterological unit: a prospective study of infective complications. | We have assessed the bacteriological safety of a system of intravenous feeding by culturing catheters on removal, swabs taken from the catheter's skin entry sites, and samples of infusion fluid. Among 38 treatment periods using 51 catheters over 1551 patient days, septicaemia due to Staphylococcus aureus was observed i... | ['Adult', 'Asepsis', 'Bacteria', 'Bacterial Infections', 'Catheterization', 'Female', 'Humans', 'Male', 'Middle Aged', 'Parenteral Nutrition', 'Prospective Studies', 'Sepsis', 'Skin', 'Staphylococcal Infections'] | 112,124 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Factors affecting exercise capacity after coronary bypass grafting]. | In order to determine the contribution of cardiac reserve and the peripheral muscle to exercise capacity in patients after Coronary Artery Bypass Grafting (CABG), 19 patients (18 males, 1 female, mean age 63.3 +/- 7.1 years, mean numbers of grafting 2.5 +/- 0.8) performed exercise tests at 1 week, 3 weeks, and 3 months... | ['Cardiac Output', 'Coronary Artery Bypass', 'Exercise Test', 'Exercise Tolerance', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Myocardial Ischemia', 'Oxygen Consumption', 'Postoperative Period'] | 9,185,439 | [['E01.370.370.380.150', 'G09.330.380.124'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['G11.427.680.270'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Volatile oil of Anethum Graveolens L. as an inhibitor of yeast and lactic acid bacteria]. | The antimicrobial activity of 25 volatile oils from aerial parts and seeds of dill (Anethum graveolens L.) of different geographical origin towards yeast Saccharomyces vini and lactic acid bacteria Lactobacterium buchneri was measured by serial dilutions. Volatile oils from mature seeds and green parts of the plants ha... | ['Cell Division', 'Lactobacillus', 'Oils, Volatile', 'Plants', 'Saccharomyces', 'Seeds', 'Species Specificity'] | 1,208,405 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['D10.627.675'], ['B01.650'], ['B01.300.107.795.785', 'B01.300.930.705'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['G16.824']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Role and mechanism of mitophagy in ventilator-induced lung injury in rats]. | OBJECTIVE: To explore the role and mechanism of mitophagy in ventilator-induced lung injury (VILI) in rats.METHODS: Thirty-six adult Sprague-Dawley (SD) rats were randomly divided into three groups (each n = 12): spontaneous breathing group (CON group), normal tidal volume (VT) group (NVT group, VT was 8 mL/kg) and hig... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Inflammation', 'Interleukin-1beta', 'Interleukin-6', 'Lung', 'Mitophagy', 'NF-kappa B', 'Rats', 'Rats, Sprague-Dawley', 'Respiration, Artificial', 'Tidal Volume', 'Tumor Necrosis Factor-alpha', 'Ventilator-Induced Lung Injury'] | 28,459,395 | [['B01.050'], ['E05.927.100.500'], ['C23.550.470'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.374.500.400.600', 'D23.529.374.465.131.600', 'D23.529.374.500.400.600'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['A04.411... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome. | Noonan syndrome (NS) is caused by mutations in RAS/ERK pathway genes, and is characterized by craniofacial, growth, cognitive and cardiac defects. NS patients with kinase-activating RAF1 alleles typically develop pathological left ventricular hypertrophy (LVH), which is reproduced in Raf1L613V/+ knock-in mice. Here, us... | ['Alleles', 'Animals', 'Coculture Techniques', 'Cytokines', 'Disease Models, Animal', 'Fibroblasts', 'Fibrosis', 'Gene Knock-In Techniques', 'Humans', 'Hypertrophy, Left Ventricular', 'Interleukin-6', 'MAP Kinase Signaling System', 'Male', 'Mice', 'Mice, Transgenic', 'Mutation', 'Myocardium', 'Myocytes, Cardiac', 'Noon... | 28,548,091 | [['G05.360.340.024.340.030'], ['B01.050'], ['E05.481.500.374'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.329.228'], ['C23.550.355'], ['E05.393.335.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.195.400', 'C23.300.775.250.400'], ['D12.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of Depression and Anxiety in Breast Cancer Patients: Prevalence and Associated Factors | Introduction: Having breast cancer or receiving treatment has been seen as a traumatic experience for women due
to its impacts on their self-image and sexual relationship, and may lead to an psychological reactions such as denial,
anger, or intense fear toward their disease and treatment process. Also many of breast ca... | ['Adult', 'Aged', 'Anxiety Disorders', 'Breast Neoplasms', 'Cohort Studies', 'Combined Modality Therapy', 'Cross-Sectional Studies', 'Depressive Disorder', 'Female', 'Follow-Up Studies', 'Greece', 'Humans', 'Middle Aged', 'Prevalence', 'Prognosis', 'Stress, Psychological'] | 29,938,451 | [['M01.060.116'], ['M01.060.116.100'], ['F03.080'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.186'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.600.300'], ['E05.318.372.500.750.249', 'N05.715.360.330... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chasing the Patagonian sun: comparative thermal biology of Liolaemus lizards. | The importance of the thermal environment for ectotherms and its relationship with thermal physiology and ecology is widely recognized. Several models have been proposed to explain the evolution of the thermal biology of ectotherms, but experimental studies have provided mixed support. Lizards from the Liolaemus goetsc... | ['Acclimatization', 'Animals', 'Argentina', 'Biological Evolution', 'Body Temperature', 'Body Temperature Regulation', 'Computational Biology', 'Likelihood Functions', 'Lizards', 'Models, Biological', 'Models, Genetic', 'Phylogeny', 'Species Specificity', 'Temperature'] | 23,011,849 | [['G07.025.133', 'G16.012.500.133'], ['B01.050'], ['Z01.107.757.077'], ['G05.045', 'G16.075'], ['E01.370.600.875.374', 'G07.110'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['H01.158.273.180', 'L01.313.124'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Decreased renal perfusion after correction of experimental coarctation. | Hemodynamical changes in coarctation were studied with an experimental model. Coarctation of the thoracic aorta was induced in seven puppies at the age of 8 wk. After a 7-month follow-up period a corrective operation with a venous patch was performed. Two dogs were lost a few hours after the correction operation. The r... | ['Animals', 'Aorta, Thoracic', 'Aortic Coarctation', 'Disease Models, Animal', 'Dogs', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Hypertension', 'Ligation', 'Renal Circulation', 'Renin', 'Reoperation', 'Surgical Flaps'] | 3,317,256 | [['B01.050'], ['A07.015.114.056.372'], ['C14.240.400.090', 'C14.280.400.090', 'C16.131.240.400.090'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.390.400.300', 'G08.852.35... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Profile of a leader: Caroline Wellwood: pragmatic visionary. | Caroline Wellwood is representative of a group of early Canadian nurses whose missionary ideals led them to innovative careers in other countries. Wellwood's visionary leadership laid the groundwork for the development of a modern system of nursing and nursing education in southwestern China. | ['Canada', 'China', 'Christianity', 'Education, Nursing, Diploma Programs', 'History, 20th Century', 'Hospitals, Religious', 'International Educational Exchange', 'Missionaries', 'Nurse Administrators', 'Religious Missions', 'Schools, Nursing'] | 11,094,942 | [['Z01.107.567.176'], ['Z01.252.474.164'], ['K01.844.188'], ['I02.358.462.482'], ['K01.400.504.968'], ['N02.278.421.481.600'], ['I01.615.500.650', 'I02.581'], ['M01.427'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580'], ['K01.844.777', 'N03.540.297.500'], ['I02.783.495.623']] | ['Geographicals [Z]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts. | Keloids are pathological scars characterized by excessive extracellular matrix production that are prone to form in body sites with increased skin tension. CAV1, the principal coat protein of caveolae, has been associated with the regulation of cell mechanics, including cell softening and loss of stiffness sensing abil... | ['Adult', 'Biopsy', 'Caveolin 1', 'Cell Movement', 'Cells, Cultured', 'Core Binding Factor Alpha 1 Subunit', 'Down-Regulation', 'Female', 'Fibroblasts', 'Gene Knockdown Techniques', 'Humans', 'Hydroxamic Acids', 'Keloid', 'Male', 'Microscopy, Atomic Force', 'Middle Aged', 'Primary Cell Culture', 'RNA, Small Interfering... | 28,899,682 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D12.644.360.024.264', 'D12.776.157.057.010', 'D12.776.476.024.280', 'D12.776.543.990.100.500', 'D12.776.744.287'], ['G04.198', 'G07.568.500.180'], ['A11.251'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neutrophil to Lymphocyte Ratio and Cardiovascular Disease Incidence in HIV-Infected Patients: A Population-Based Cohort Study. | Neutrophil to lymphocyte ratio (NLR) has been shown to predict occurrence of cardiovascular events in the general population. The aim of our study was to evaluate the role of NLR to predict major cardiovascular disease (CVD) events in HIV-infected subjects. We performed a retrospective cohort study of HIV-infected pati... | ['Adult', 'Cardiovascular Diseases', 'Case-Control Studies', 'Female', 'HIV Infections', 'Humans', 'Incidence', 'Italy', 'Lymphocyte Count', 'Male', 'Middle Aged', 'Neutrophils', 'ROC Curve', 'Retrospective Studies', 'Risk Factors'] | 27,148,878 | [['M01.060.116'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Consultation-referral among physicians: practice and process. | Consultation-referral is a part of everyday family practice. Although the process is taken for granted, it is a complex phenomenon. Neither the practice nor the process always meet the expectations of the referring physician or the consultant, and the patient may be the worse because of this discrepany. Studies of the ... | ['Canada', 'Family Practice', 'Follow-Up Studies', 'Humans', 'Interprofessional Relations', 'Referral and Consultation', 'United Kingdom', 'United States'] | 621,471 | [['Z01.107.567.176'], ['H02.403.340.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['N04.452.758.849'], ['Z01.542.363'], ['Z01.107.567.875']] | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Cation dependent O-methyltransferases from rice. | Two lower molecular mass OMT genes (ROMT-15 and -17) were cloned from rice and expressed in Escherichia coli as glutathione S-transferase fusion proteins. ROMT-15 and -17 metabolized caffeoyl-CoA, flavones and flavonols containing two vicinal hydroxyl groups, although they exhibited different substrate specificities. T... | ['Acyl Coenzyme A', 'Binding Sites', 'Catalysis', 'Cations', 'Flavonoids', 'Gene Expression', 'Methylation', 'Methyltransferases', 'Molecular Weight', 'Oryza', 'Substrate Specificity'] | 17,943,312 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['G02.111.570.120'], ['G02.130'], ['D01.248.497.300'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G05.297'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D08.811.913.555.500'], ['G02... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The tetratricopeptide repeat-domain of the PAS10 protein of Saccharomyces cerevisiae is essential for binding the peroxisomal targeting signal-SKL. | The PAS10 gene was found in a two-hybrid screen for the isolation of genes encoding proteins which interact with the C-terminal peroxisomal targeting signal -SKL. The PAS10 protein is known to be involved in import of proteins into peroxisomes and to contain a tetratricopeptide repeat (TPR) domain. All TPR-containing p... | ['Amino Acid Sequence', 'Base Sequence', 'Carrier Proteins', 'Fungal Proteins', 'Genes, Fungal', 'Membrane Transport Proteins', 'Microbodies', 'Molecular Sequence Data', 'Mutagenesis, Insertional', 'Peroxisome-Targeting Signal 1 Receptor', 'Plasmids', 'Protein Sorting Signals', 'Repetitive Sequences, Nucleic Acid', 'Sa... | 7,980,572 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157'], ['D12.776.354'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D12.776.157.530', 'D12.776.543.585'], ['A11.284.430.214.190.500.585', 'A11.284.430.214.190.87... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
CovR and VicRK regulate cell surface biogenesis genes required for biofilm formation in Streptococcus mutans. | The two-component system VicRK and the orphan regulator CovR of Streptococcus mutans co-regulate a group of virulence genes associated with the synthesis of and interaction with extracellular polysaccharides of the biofilm matrix. Knockout mutants of vicK and covR display abnormal cell division and morphology phenotype... | ['Bacterial Proteins', 'Biofilms', 'Gene Expression Profiling', 'Repressor Proteins', 'Streptococcus mutans', 'Sucrose'] | 23,554,881 | [['D12.776.097'], ['A20.593', 'G06.120'], ['E05.393.332'], ['D12.776.260.703', 'D12.776.930.780'], ['B03.353.750.737.872.875.520', 'B03.510.400.800.872.875.520', 'B03.510.550.737.872.875.520'], ['D09.698.629.305.770', 'D09.947.750.770']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple Roles for Egalitarian in Polarization of the Drosophila Egg Chamber. | The Drosophila egg chamber provides a useful model for examining mechanisms by which cell fates are specified and maintained in the context of a complex tissue. The egg chamber is also an excellent model for understanding the mechanism by which cytoskeletal filaments are organized and the critical interplay between cyt... | ['Animals', 'Drosophila', 'Drosophila Proteins', 'Female', 'Microtubules', 'Oocytes', 'Oogenesis', 'RNA, Messenger'] | 27,017,624 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['A11.284.430.214.190.750.602'], ['A05.360.490.690.680', 'A11.497.497.600'], ['G04.152.650.249', 'G08.686.784.310.500'], ['D13.444.735.544']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of designer steroid methylstenbolone in "nutritional supplement" using gas chromatography and tandem mass spectrometry: elucidation of its urinary metabolites. | The use of "nutritional supplements" containing unapproved substances has become a regular practice in amateur and professional athletes. This represents a dangerous habit for their health once no data about toxicological or pharmacological effects of these supplements are available. Most of them are freely commerciali... | ['Adult', 'Androstenols', 'Chromatography, Gas', 'Designer Drugs', 'Dietary Supplements', 'Humans', 'Kinetics', 'Male', 'Steroids', 'Tandem Mass Spectrometry', 'Time Factors'] | 23,200,734 | [['M01.060.116'], ['D04.210.500.054.079.429'], ['E05.196.181.349'], ['D26.909.500'], ['G07.203.300.456', 'J02.500.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D04.210.500'], ['E05.196.566.880'], ['G01.910.857']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Association of transporter associated with antigen processing (TAP) gene polymorphisms in donors with acute cellular rejection in living donor liver transplantation. | BACKGROUND & AIMS: Despite improvements in immunosuppressive therapy, acute cellular rejection (ACR) remains an important cause of mortality and graft loss in patients undergoing liver transplantation. Recently, associations between gene polymorphisms and the incidence of ACR have been reported, though few studies have... | ['ATP Binding Cassette Transporter, Subfamily B, Member 2', 'ATP Binding Cassette Transporter, Subfamily B, Member 3', 'ATP-Binding Cassette Transporters', 'Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disea... | 23,799,215 | [['D12.776.157.530.100.075.250', 'D12.776.157.530.450.074.500.500.250.250', 'D12.776.395.550.020.400.305', 'D12.776.543.550.192.400.305', 'D12.776.543.585.100.200.250', 'D12.776.543.585.450.074.500.500.250.250'], ['D12.776.157.530.100.075.500', 'D12.776.157.530.450.074.500.500.250.375', 'D12.776.395.550.020.400.458', '... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Predictors of cardiovascular response to smoked cocaine in humans. | The purpose of this study was to examine the predictors of heart rate and blood pressure changes following cocaine administration. Sixty-two smoked cocaine users received a single 0.4 mg/kg dose of smoked cocaine. Male sex, African American race, higher body weight and current marijuana use predicted a greater cardiova... | ['Administration, Inhalation', 'Adult', 'Arousal', 'Blood Pressure', 'Cocaine-Related Disorders', 'Crack Cocaine', 'Female', 'Heart Rate', 'Humans', 'Male'] | 10,661,674 | [['E02.319.267.050'], ['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C25.775.300', 'F03.900.300'], ['D02.145.074.722.388.250', 'D03.132.889.354.250', 'D03.605.084.500.722.388.250', 'D03.605.869.388.250', 'D26.878.250'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
POMC mRNA levels in individual melanotropes and GFAP in glial-like cells in rat pituitary. | In this study we demonstrated that individual melanotropes expressed differing levels of POMC mRNA. Interspersed among the melanotropes was a small population of process-bearing cells expressing GFAP. We compared cellular resolution and feasibility for quantitation of hybrids formed by oligonucleotide probes labeled wi... | ['Animals', 'Base Sequence', 'Bromocriptine', 'Glial Fibrillary Acidic Protein', 'Haloperidol', 'Histocytochemistry', 'Image Processing, Computer-Assisted', 'Immunohistochemistry', 'In Situ Hybridization', 'Male', 'Melanins', 'Molecular Sequence Data', 'Neuroglia', 'Pituitary Gland', 'Pro-Opiomelanocortin', 'RNA, Messe... | 8,008,629 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['D02.522.352.506'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Analysis of vasoreactivity of isolated human radial artery. | Radial artery (RA) is increasingly used as graft for coronary artery bypass grafting due to its good long-term patency. However, the mechanism of peri- and post-operative spasm is still unclear. Because of that, the aim of our study is to analyze the contractility of RA and to determine whether the presence of function... | ['Angiotensin II', 'Dose-Response Relationship, Drug', 'Electric Stimulation', 'Endothelium, Vascular', 'Humans', 'In Vitro Techniques', 'Muscle, Smooth, Vascular', 'Phenylephrine', 'Radial Artery', 'Serotonin', 'Time Factors', 'Vasoconstriction', 'Vasoconstrictor Agents'] | 16,404,133 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.723.402'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A02.633.570.49... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Essential regions for antiviral activities of actinohivin, a sugar-binding anti-human immunodeficiency virus protein from an actinomycete. | Actinohivin (AH) is a potent anti-human immunodeficiency virus (HIV) protein that consists of highly conserved three-tandem repeats (segments 1, 2, and 3). The molecular target of AH in its anti-HIV activity is high-mannose-type saccharide chains of HIV gp120. This article deals with sequence requirements for the anti-... | ['Actinobacteria', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Anti-HIV Agents', 'Bacterial Proteins', 'Carbohydrate Metabolism', 'Conserved Sequence', 'Cysteine', 'Enzyme-Linked Immunosorbent Assay', 'Giant Cells', 'HIV', 'HeLa Cells', 'Humans', 'Inhibitory Concentration 50', 'Molecular Sequence Data', 'Sequenc... | 15,850,563 | [['B03.510.024', 'B03.510.460.400.400.049'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['D27.505.954.122.388.077.088'], ['D12.776.097'], ['G02.111.158', 'G03.191'], ['G02.111.570.580'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E05.478.566.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Inositol trisphosphate and diacylglycerol can differentially modulate gene expression in Dictyostelium. | We have previously shown that several genes expressed during Dictyostelium development could be induced in shaking culture by exogenous cAMP, even though the accumulation of intracellular cAMP was inhibited. The use of selected cAMP analogs indicated that the exogenous cAMP functioned by activating the cell surface cAM... | ['Cyclic AMP', 'Dictyostelium', 'Diglycerides', 'Gene Expression', 'Gene Expression Regulation, Fungal', 'Genes, Fungal', 'Glycerides', 'Inositol 1,4,5-Trisphosphate', 'RNA, Fungal'] | 2,556,709 | [['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.046.550.200.300'], ['D10.351.303'], ['G05.297'], ['G05.308.330'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D10.351'], ['D02.033.800.519.400.350', 'D09.853.519.400.350'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity. | Bacterial sensing by intracellular Nod proteins and other Nod-like receptors (NLRs) activates signaling pathways that mediate inflammation and pathogen clearance. Nod1 and Nod2 associate with the kinase Rip2 to stimulate NF-kappaB signaling. Other cytosolic NLRs assemble caspase-1-activating multiprotein complexes term... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Antimicrobial Cationic Peptides', 'Caspase 12', 'Citrobacter rodentium', 'Cytokines', 'Enterobacteriaceae Infections', 'Epithelial Cells', 'Female', 'Humans', 'Immunity, Mucosal', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'NF-kappa B', 'Nod1 Signaling Adaptor P... | 18,329,614 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D12.644.050', 'D12.776.543.695.054'], ['D08.811.277.656.262.500.126.550.920', 'D08.811.277.656.300.200.126.550.920', 'D12.644.360.075.405.550.920', 'D12.776.476.075.405.550.920'], ['B03.440.450.425.200.737', 'B03.660.250.150.100.737'], ['D12.644... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter. | By mediating the coupled movement of Na, K, and Cl ions across the plasma membrane of most animal cells, the bumetanide-sensitive Na-K-Cl cotransporter (NKCC) plays a vital role in the regulation of ionic balance and cell volume. The transporter is a central element in the process of vectorial salt transport in secreto... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Bumetanide', 'Carrier Proteins', 'Cell Line', 'Chlorides', 'Cloning, Molecular', 'DNA', 'Gene Expression Regulation', 'Humans', 'Molecular Sequence Data', 'Osmolar Concentration', 'Potassium', 'Sharks', 'Sodium', 'Sodium-Potassium-Chloride Sympo... | 8,134,373 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D02.065.884.150', 'D02.241.223.100.050.300.200', 'D02.455.426.559.389.127.020.452.500', 'D02.886.590.700.150'], ['D12.776.157'], ['A11.251.210'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Light-induced vasodilation of coronary arteries and its possible clinical implication. | BACKGROUND: Low-level laser therapy and light-emitting diodes (LED) are increasingly used in phototherapy. Their therapeutic effects are at least partly mediated by light-induced vasodilation. The aim of this study was to determine the effect of different light sources on coronary arteries.METHODS: Porcine left coronar... | ['Animals', 'Coronary Vessels', 'Light', 'Low-Level Light Therapy', 'Models, Animal', 'Phototherapy', 'Swine', 'Vasodilation'] | 22,381,453 | [['B01.050'], ['A07.015.114.269', 'A07.015.908.194'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E02.594.540', 'E02.774.500'], ['E05.598'], ['E02.774'], ['B01.050.150.900.649.313.500.880'], ['G09.330.380.928']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Different binding capacities of influenza A and Sendai viruses to gangliosides from human granulocytes. | The structures of gangliosides from human granulocytes were elucidated by fast atom bombardment mass spectrometry and by gas chromatography/mass spectrometry as their partially methylated alditol acetates. In human granulocytes besides GM3 (II3Neu5Ac-LacCer), neolacto-series gangliosides (IV3Neu5Ac-nLcOse4Cer, IV6Neu5A... | ['Carbohydrate Sequence', 'Chromatography, Gas', 'Chromatography, Thin Layer', 'Gangliosides', 'Granulocytes', 'Humans', 'Influenza A virus', 'Molecular Sequence Data', 'Parainfluenza Virus 1, Human', 'Receptors, Virus', 'Spectrometry, Mass, Fast Atom Bombardment', 'Sulfur Radioisotopes'] | 8,395,268 | [['G02.111.570.160', 'L01.453.245.667.160'], ['E05.196.181.349'], ['E05.196.181.400.537'], ['D09.400.410.420.025.475', 'D10.390.470.025.475', 'D10.570.877.360.025.475'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['B01.050.150.900.649.313.988.400.112.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Bone tunnel enlargement after anterior cruciate ligament reconstruction using hamstring tendons. | We retrospectively reviewed 87 anterior cruciate ligament reconstructions using autogenous hamstring tendons with the Endobutton technique to investigate the relationship between bone tunnel enlargement and clinical outcome and to identify factors that contribute to the enlargement. The clinical outcome was evaluated u... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament Injuries', 'Biomechanical Phenomena', 'Female', 'Humans', 'Knee Injuries', 'Male', 'Middle Aged', 'Orthopedic Procedures', 'Reconstructive Surgical Procedures', 'Rupture', 'Tendons'] | 11,522,075 | [['M01.060.057'], ['M01.060.116'], ['C26.558.554.213'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['M01.060.116.630'], ['E02.718', 'E04.555'], ['E04.680'], ['C26.761'], ['A02.880']] | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risperidone and haloperidol promote survival of stem cells in the rat hippocampus. | Altered neuroplasticity contributes to the pathophysiology of schizophrenia. However, the idea that antipsychotics may act, at least in part, by normalizing neurogenesis has not been consistently supported. Our study seeks to determine whether hippocampal cell proliferation is altered in adult rats pretreated with keta... | ['Adult Stem Cells', 'Animals', 'Antipsychotic Agents', 'Bromodeoxyuridine', 'Cell Proliferation', 'Cell Survival', 'Gene Expression Regulation', 'Haloperidol', 'Hippocampus', 'In Situ Nick-End Labeling', 'Male', 'Models, Animal', 'Nerve Tissue Proteins', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Risperidone',... | 19,579,000 | [['A11.872.040'], ['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G05.308'], ['D02.522.352.506'], ['A08.186.211.180.405', 'A08... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does familiarity affect the enjoyment of touchscreen games for people with dementia? | INTRODUCTION: Previous research has indicated that people living with dementia are able to use touchscreen technology, which presents an opportunity to deliver meaningful and engaging activities for people to pass the time independently. The challenge is to identify suitable applications from the thousands that are cur... | ['Aged', 'Aged, 80 and over', 'Dementia', 'Female', 'Humans', 'Male', 'Memory', 'Pleasure', 'Recognition, Psychology', 'Touch', 'User-Computer Interface', 'Video Games'] | 26,897,552 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F01.470.867', 'F02.830.816.492'], ['F02.463.425.540.706'], ['F02.830.816.850', 'G11.561.790.850'], ['L01.224.900.910'], ['I03.450.642.693.930', 'L01.224.900.930']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Modeling early stage atherosclerosis in a primary human vascular microphysiological system. | Novel atherosclerosis models are needed to guide clinical therapy. Here, we report an in vitro model of early atherosclerosis by fabricating and perfusing multi-layer arteriole-scale human tissue-engineered blood vessels (TEBVs) by plastic compression. TEBVs maintain mechanical strength, vasoactivity, and nitric oxide ... | ['Arterioles', 'Atherosclerosis', 'Biomechanical Phenomena', 'Cell Adhesion', 'Cell Proliferation', 'Cells, Cultured', 'Foam Cells', 'Humans', 'Lipoproteins, LDL', 'Models, Biological', 'Monocytes', 'Nitric Oxide', 'Tissue Engineering', 'Tumor Necrosis Factor-alpha'] | 33,110,060 | [['A07.015.114.060', 'A07.015.461.080'], ['C14.907.137.126.307'], ['G01.154.090', 'G01.374.089'], ['G04.022'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['A11.329.372.368', 'A11.627.482.368', 'A11.733.397.368', 'A15.382.670.522.368', 'A15.382.680.397.368'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effects of Long-Term Denosumab on Bone Histomorphometry and Mineralization in Women With Postmenopausal Osteoporosis. | Context: Denosumab is a potent antiresorptive agent that reduces fractures in postmenopausal women with osteoporosis.Objective: Determine effects of up to 10 years of denosumab on bone histology, remodeling, and matrix mineralization characteristics.Design and Setting: International, multicenter, randomized, double-bli... | ['Aged', 'Bone Density Conservation Agents', 'Bone Remodeling', 'Calcification, Physiologic', 'Denosumab', 'Double-Blind Method', 'Drug Administration Schedule', 'Female', 'Humans', 'Middle Aged', 'Osteoporosis, Postmenopausal', 'Time Factors', 'Treatment Outcome'] | 29,672,714 | [['M01.060.116.100'], ['D27.505.696.242'], ['G11.427.213', 'G16.762.150'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['D12.776.124.486.485.114.224.060.782', 'D12.776.124.790.651.114.224.060.782', 'D12.776.377.715.548.114.224.200.782'], ['E05.318.370.300', 'E05.581.500.300', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Illicit methadone injecting during methadone maintenance treatment in a specialised out-patient clinic. | AIM: The injection of non-sterile methadone designed for oral consumption is associated with serious health risks. There is only a small number of studies on this topic, with divergent results. The main aim of the present study was to obtain data on the frequency of methadone injecting in a state out-patient clinic spe... | ['Adult', 'Ambulatory Care Facilities', 'Cross-Sectional Studies', 'Female', 'Humans', 'Injections, Intravenous', 'Male', 'Methadone', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Switzerland'] | 16,380,851 | [['M01.060.116'], ['N02.278.035'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D02.522.675'], ['C25.775', 'F03.900'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], [... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Influence of blood pressure control on maintenance of residual function in patients treated by haemodialysis]. | INTRODUCTION: Residual renal function (RRF) in the patients treated by haemodialysis (HD) is associated not only with better volume and blood pressure control but also with better metabolic control.The condition of the cardiovascular system significantly affects RRF.OBJECTIVE: The aim of the study was to find if there ... | ['Blood Pressure', 'Female', 'Humans', 'Kidney', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Urea'] | 19,459,562 | [['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E02.870.300', 'E02.912.800'], ['D02.065.950']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cancer. A potentially preventable disease. | Current epidemiologic and carcinogenesis data are lending credence to the hypothesis that individual cancers have specific causes. Because of this, most cancers are at least potentially preventable. Primary prevention, with removal of specific etiological agents, is the best means of prevention, such as elimination of ... | ['Aspirin', 'Environmental Exposure', 'Female', 'Finasteride', 'Humans', 'Isotretinoin', 'Life Style', 'Male', 'Middle Aged', 'Neoplasms', 'Risk Factors', 'Tamoxifen'] | 7,775,840 | [['D02.455.426.559.389.657.410.595.176'], ['N06.850.460.350'], ['D04.210.500.054.079.500', 'D04.210.500.925.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.271.665.202.495.325', 'D02.455.426.392.368.367.379.249.700.325', 'D02.455.849.131.495.325', 'D23.767.261.700.325'], ['F01.829.458'], ['M01... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
BrainLab VectorVision Neuronavigation System: technology and clinical experiences in 131 cases. | OBJECTIVE: The BrainLab VectorVision neuronavigation system was used in 131 cases of different brain pathological conditions. The neuronavigation system was used without problems in 125 cases. These cases included 114 microsurgical operations, 4 endoscopic procedures, 4 frameless stereotactic biopsies, and 3 catheter p... | ['Biopsy', 'Brain', 'Brain Diseases', 'Brain Neoplasms', 'Computer Systems', 'Endoscopes', 'Equipment Failure Analysis', 'Humans', 'Image Processing, Computer-Assisted', 'Microsurgery', 'Robotics', 'Stereotaxic Techniques', 'Surgical Equipment', 'Surgical Instruments', 'Video Recording'] | 9,894,969 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A08.186.211'], ['C10.228.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['L01.224.230'], ['E07.230.220', 'E07.858.240'], ['E05.325.192'], ['B01.050.150... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Pharmacodynamics of T cell function for monitoring pharmacologic immunosuppression after allogeneic hematopoietic stem cell transplantation. | Information on pharmacodynamic monitoring after allogeneic hematopoietic cell transplantation (allo-SCT) to evaluate individual responses to immunosuppressive drugs is scarce. We studied the relationship between a panel of pharmacodynamic markers monitored during the first 3 months after transplant and the occurrence o... | ['Adult', 'Aged', 'Allografts', 'Biomarkers', 'CD4-CD8 Ratio', 'Drug Monitoring', 'Female', 'Graft vs Host Disease', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Immunosuppression', 'Immunosuppressive Agents', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Pilot Projects', 'T-Lymphocytes'] | 27,882,485 | [['M01.060.116'], ['M01.060.116.100'], ['A01.941.500'], ['D23.101'], ['E01.370.225.500.195.107.595.500.150.160', 'E01.370.225.625.107.595.500.150.160', 'E05.200.500.195.107.595.500.150.160', 'E05.200.625.107.595.500.150.160', 'E05.242.195.107.595.500.150.160', 'G04.140.107.595.500.150.160', 'G09.188.105.595.500.150.160... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Focusing and targeting gallstones during extracorporeal shock waves lithotripsy]. | The gallbladder lies at the junction of the medial segment of the left and right hepatic lobes. Besides the anatomic location, other factors may interfere with an ideal targeting of gallstones during extracorporeal shock waves treatment. Obesity, malnourishment, the respiratory cycle, the presence of intestinal gas, an... | ['Cholelithiasis', 'Gallbladder', 'Gallstones', 'Gases', 'Gastrointestinal Contents', 'Humans', 'Intestines', 'Lithotripsy', 'Obesity', 'Posture', 'Ultrasonography'] | 19,256,141 | [['C06.130.409'], ['A03.159.439'], ['C06.130.409.633', 'C06.130.564.332.500', 'C23.300.175.525'], ['D01.362'], ['A12.519'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['E02.600', 'E04.943.500'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Leg amputation accelerates senescence of rat lumbar intervertebral discs. | STUDY DESIGN: Several senescence biomarkers were observed to investigate cell senescence in degenerative intervertebral lumbar discs of foreleg-amputated rats.OBJECTIVE: To determine if cell senescence is accelerated in degenerative intervertebral lumbar disc cells in an upright-rat model.SUMMARY OF BACKGROUND DATA: Ce... | ['Amputation', 'Analysis of Variance', 'Animals', 'Biomarkers', 'Cellular Senescence', 'Cyclin-Dependent Kinase Inhibitor p27', 'Forelimb', 'Gene Expression', 'Genes, p16', 'Immunohistochemistry', 'Intervertebral Disc', 'Lumbar Vertebrae', 'Male', 'RNA, Messenger', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', '... | 20,938,386 | [['E04.555.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D23.101'], ['G04.043'], ['D12.644.360.225.600', 'D12.776.167.187.600', 'D12.776.476.225.600', 'D12.776.624.776.355.600'], ['A13.395'], ['G05.297'], ['G05.360.340.024.340.375.249.375', 'G05.360.340.024.340.415.400.375'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
13 | The Y145Stop prion protein (PrP23-144), which has been linked to the development of a heritable prionopathy in humans, is a valuable in vitro model for elucidating the structural and molecular basis of amyloid seeding specificities. Here we report the sequential backbone and side-chain 13C and 15N assignments of mouse ... | ['Amino Acid Sequence', 'Amyloid', 'Animals', 'Cricetinae', 'Mice', 'Nuclear Magnetic Resonance, Biomolecular', 'Peptide Fragments', 'Prion Proteins', 'Protein Multimerization', 'Protein Structure, Secondary'] | 28,004,358 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D05.500.049', 'D12.776.049'], ['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.196.867.519.550'], ['D12.644.541'], ['D12.776.395.550.448.600', 'D12.776.543.484.500.625', 'D12.776.543.550.418.600', 'D12.776.785.340... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Production of interleukin-12 is under the control of endogenous interleukin-10 in myocardial ischemia-reperfusion. | Interleukin (IL)-12 is a heterodimeric cytokine that is secreted mainly by antigen-presenting cells and plays a key role in determining the nature of immune response to exogenous or endogenous antigens. Negative regulators of IL-12 production include IL-10. With use of wild-type and IL-10-deficient mice, the aim of the... | ['Animals', 'Interleukin-10', 'Interleukin-12', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Myocardial Ischemia', 'Myocardial Reperfusion Injury'] | 11,198,362 | [['B01.050'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['D12.644.276.374.465.512', 'D12.776.467.374.465.512', 'D23.529.374.465.512'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.