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Short-course therapy with zidovudine plus lamivudine for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Thailand. | To evaluate the efficacy and safety of short-course therapy with zidovudine plus lamivudine for reduction of perinatal transmission of human immunodeficiency virus type 1 (HIV-1), a single-arm, open-label, prospective, nonrandomized study was conducted. One hundred six treatment-naive pregnant women received zidovudine... | ['Adolescent', 'Adult', 'Anti-HIV Agents', 'Drug Administration Schedule', 'Female', 'HIV Infections', 'HIV-1', 'Humans', 'Infectious Disease Transmission, Vertical', 'Lamivudine', 'Prospective Studies', 'Thailand', 'Zidovudine'] | 12,439,805 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E02.319.283'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.875'], ['D03.38... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Excellent survival of pediatric dermatofibrosarcoma protuberans in Taiwanese. | The purpose of this study was to explore the clinical outcome of pediatric dermatofibrosarcoma protuberans (DFSP) in Taiwan. Patients with DFSP diagnosed before 18 years and treated in our institute from 1977 to 2002 were identified through institutional cancer registry. After approved by institutional research ethic c... | ['Adolescent', 'Child', 'Child, Preschool', 'Dermatofibrosarcoma', 'Disease-Free Survival', 'Female', 'Humans', 'Infant', 'Male', 'Prognosis', 'Skin Neoplasms', 'Survival Rate', 'Taiwan'] | 17,109,179 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C04.557.450.565.590.350.320', 'C04.557.450.795.350.320'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Age as an independent prognostic factor for survival of localised synovial sarcoma patients. | BACKGROUND: We performed a retrospective nationwide study to explore age as a prognostic factor in synovial sarcoma patients.METHODS: Data on 613 synovial sarcoma patients were obtained from the Netherlands Cancer Registry. The prognostic relevance of age groups (children, adolescent and young adults (AYAs), adults, an... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Netherlands', 'Proportional Hazards Models', 'Registries', 'Retrospective Studies', 'Sarcoma, Synovial', 'Survival Rate', 'Young Adult'] | 26,554,650 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['Z01.542.65... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Blood pressure in Navajo Indians and its association with type 2 diabetes and renal and cardiovascular disease. | In mid-1990 we evaluated blood pressure and its associations in 366 nondiabetic adult Navajos and 400 Navajos with type 2 diabetes attending Indian Health Service outpatient clinics in Tuba City, Arizona. In nondiabetics, systolic blood pressure (SBP) rose with increasing age while diastolic blood pressure (DBP) fell; ... | ['Adult', 'Albuminuria', 'Antihypertensive Agents', 'Blood Pressure', 'Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Diabetic Nephropathies', 'Female', 'Humans', 'Indians, North American', 'Kidney Diseases', 'Male', 'Middle Aged'] | 8,031,547 | [['M01.060.116'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['B01.050.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset. | OBJECTIVE: Calcinosis is a major cause of morbidity in JDM and has previously been linked to anti-NXP2 autoantibodies, younger age at disease onset and more persistent disease activity. This study aimed to investigate the clinical associations of anti-NXP2 autoantibodies in patients with JDM stratified by age at diseas... | ['Adenosine Triphosphatases', 'Age of Onset', 'Autoantibodies', 'Biomarkers', 'Calcinosis', 'Child', 'Child, Preschool', 'Cohort Studies', 'DNA-Binding Proteins', 'Dermatomyositis', 'Female', 'Humans', 'Male', 'Muscle Weakness', 'Prognosis', 'Risk Assessment', 'Severity of Illness Index'] | 24,987,158 | [['D08.811.277.040.025'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.101'], ['C18.452.174.130'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence of diabetes in Mexican Americans, Cubans, and Puerto Ricans from the Hispanic Health and Nutrition Examination Survey, 1982-1984. | The purpose of this study was to estimate the prevalence of diagnosed and undiagnosed diabetes among Mexican Americans, Cubans, and Puerto Ricans in the United States and compare these estimates to data from prior surveys for U.S. non-Hispanic whites and blacks. Data for this study are from the Hispanic Health and Nutr... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Cuba', 'Diabetes Mellitus', 'Female', 'Health Surveys', 'Hispanic Americans', 'Humans', 'Male', 'Mexico', 'Middle Aged', 'Nutrition Surveys', 'Prevalence', 'Puerto Rico', 'United States'] | 1,914,812 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.107.084.900.225', 'Z01.639.880.225'], ['C18.452.394.750', 'C19.246'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['M01.686.754.441'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adrenergic stimulation of the lateral hypothalamic area on sodium and potassium excretion. | The effects of adrenergic stimulation of the lateral hypothalamic area on sodium and potassium excretion were studied in rats bearing implanted cannulae. When noradrenaline was injected into several points of the lateral hypothalamic area, a dose-related increase in natriuresis and kaliuresis was observed. Rats previou... | ['Animals', 'Dose-Response Relationship, Drug', 'Hypothalamus', 'Lidocaine', 'Nialamide', 'Norepinephrine', 'Phentolamine', 'Potassium', 'Propranolol', 'Rats', 'Receptors, Adrenergic', 'Sodium'] | 870,902 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['D03.066.349.490', 'D03.383.725.394.628'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mutants of Micromonospora viridifaciens sialidase have highly variable activities on natural and non-natural substrates. | This study aimed to improve the hydrolase activity of the well-characterised bacterial sialidase from Micromonospora viridifaciens. The enzyme and its mutated versions were produced in Bacillus subtilis and secreted to the growth medium. Twenty amino acid positions in or near the active site were subjected to site-satu... | ['Bacterial Proteins', 'Evolution, Molecular', 'Micromonospora', 'Muramic Acids', 'Mutation', 'Neuraminidase', 'Substrate Specificity'] | 25,573,534 | [['D12.776.097'], ['G05.045.250', 'G16.075.250'], ['B03.300.390.400.500.500', 'B03.510.024.925.500', 'B03.510.415.400.500.500', 'B03.510.460.410.500.500'], ['D02.241.081.844.520', 'D02.241.511.902.522', 'D09.067.550', 'D09.811.522'], ['G05.365.590'], ['D08.811.277.450.692'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Specific high-affinity binding of the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate to isolated nuclei and nuclear macromolecules in mouse epidermis. | The tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) binds reversibly and with high affinity and specificity to nuclear macromolecules in mouse epidermis. The dissociation constants determined from Scatchard analysis of epidermal nuclei and nuclear macromolecules are 3.58 +/- 0.66 (S.E.) and 2.18 +/- 0.54 nM, ... | ['Animals', 'Binding Sites', 'Cell Fractionation', 'Cell Nucleus', 'Chromatin', 'DNA', 'Deoxyribonuclease I', 'Deoxyribonucleases', 'Endonucleases', 'Epidermis', 'Female', 'Mice', 'Phorbols', 'Proteins', 'Tetradecanoylphorbol Acetate'] | 6,286,108 | [['B01.050'], ['G02.111.570.120'], ['E05.242.251'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308'], ['D08.811.277.352.335.350.250'], ['D08.811.277.352.335'], ['D08.811.277.352.355'], ['A10.272.497', 'A17.815.250'], ['B01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Floating pellets containing bacterial antagonist for control sheath blight of rice: formulations, viability and bacterial release studies. | Floating pellets containing spores of bacterial biological control agent, Bacillus megaterium were prepared by extrusion-spheronization process. The formulations composed of hydrogenated vegetable oil (HVO), lactose, microcrystalline cellulose (Avicel(R) PH101), and a disintegrant; cross-linked sodium carboxymethylcell... | ['Anti-Bacterial Agents', 'Bacillus megaterium', 'Cell Survival', 'Chemistry, Pharmaceutical', 'Delayed-Action Preparations', 'Drug Carriers', 'Drug Evaluation, Preclinical', 'Drug Implants', 'Rhizoctonia', 'Technology, Pharmaceutical'] | 15,023,457 | [['D27.505.954.122.085'], ['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['G04.346'], ['H01.158.703.007', 'H01.181.466'], ['D26.255.210', 'E02.319.300.253'], ['D26.255.260', 'E02.319.300.380'], ['E05.290.750', 'E05.337... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Outbreaks of Bemisia tabaci | The whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae), is one of the most important agricultural pests and virus vectors worldwide. Bemisia tabaci is considered a complex of cryptic species with at least 44 species. Among them, the species Middle East-Asia Minor 1 (MEAM1, formerly B biotype) and Mediterrane... | ['Animals', 'Begomovirus', 'Brazil', 'Crinivirus', 'Crops, Agricultural', 'Disease Outbreaks', 'Hemiptera', 'Introduced Species', 'Microsatellite Repeats', 'Plant Diseases', 'Symbiosis', 'Vegetables'] | 31,987,066 | [['B01.050'], ['B04.280.350.100', 'B04.715.270.100'], ['Z01.107.757.176'], ['B04.715.110.175', 'B04.820.578.313.175'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['N06.850.290'], ['B01.050.500.131.617.412'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['G02.111.570.080.708.800.500', '... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Substrate binding induces a cooperative conformational change in the 12S subunit of transcarboxylase: Raman crystallographic evidence. | The 12S subunit of transcarboxylase is a 338 000 Da hexamer that transfers carboxlylate from methylmalonyl-CoA (MM-CoA) to biotin; in turn, the biotin transfers the carboxylate to pyruvate on another subunit, the 5S. Here, Raman difference microscopy is used to study the binding of substrate and product, and their anal... | ['Acyl Coenzyme A', 'Binding Sites', 'Carboxyl and Carbamoyl Transferases', 'Crystallization', 'Crystallography, X-Ray', 'Malonyl Coenzyme A', 'Propionibacterium', 'Protein Conformation', 'Protein Subunits', 'Spectrum Analysis, Raman', 'Substrate Specificity'] | 12,196,011 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['G02.111.570.120'], ['D08.811.913.555.275'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['D03.633.100.759.646.138.382.300.500', 'D08.211.211.300.500', 'D13.695.667.138.382.300.500', 'D13.695.827.068... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacteria, phages and septicemia. | The use of phages is an attractive option to battle antibiotic resistant bacteria in certain bacterial infections, but the role of phage ecology in bacterial infections is obscure. Here we surveyed the phage ecology in septicemia, the most severe type of bacterial infection. We observed that the majority of the bacteri... | ['Bacterial Physiological Phenomena', 'Bacteriophages', 'Humans', 'Microscopy, Electron', 'Sepsis'] | 18,188,406 | [['G06.099'], ['B04.123'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['C01.757', 'C23.550.470.790.500']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural basis of AMPK regulation by adenine nucleotides and glycogen. | AMP-activated protein kinase (AMPK) is a central cellular energy sensor and regulator of energy homeostasis, and a promising drug target for the treatment of diabetes, obesity, and cancer. Here we present low-resolution crystal structures of the human á1â2ã1 holo-AMPK complex bound to its allosteric modulators AMP and ... | ['AMP-Activated Protein Kinases', 'Adenosine Monophosphate', 'Adenosine Triphosphate', 'Allosteric Regulation', 'Crystallography, X-Ray', 'Cyclodextrins', 'Glycogen', 'Humans', 'Models, Molecular', 'Phosphorylation', 'Protein Conformation', 'Protein Subunits'] | 25,412,657 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.044'], ['E05.196.309.742.225'], ['D04.345.103', 'D09.301.915.400.375', 'D09.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A contemporary analysis of clinical and demographic factors of chronic rhinosinusitis patients and their association with disease severity. | BACKGROUND: Chronic rhinosinusitis (CRS) is highly prevalent, significantly decreases quality of life and leads to tremendous health care costs every year. No recent study has characterised the prevalence of potentially CRS-modifying patient characteristics and simultaneously shown their impact on CRS severity.AIMS: We... | ['Chronic Disease', 'Comorbidity', 'Demography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Retrospective Studies', 'Rhinitis', 'Sinusitis', 'Surveys and Questionnaires'] | 28,560,517 | [['C23.550.291.500'], ['N05.715.350.225', 'N06.850.490.687'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', ... | ['Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Enlarged psoas muscle and iliopsoas bursitis associated with a rapidly destructive hip in a patient with rheumatoid arthritis. | A 39-year-old man with rheumatoid arthritis developed femoral neuropathy secondary to iliopsoas bursitis. The adjacent hip joint was severely damaged. Magnetic resonance imaging showed enlargement and inflammation of the psoas muscle at the same side of iliopsoas bursitis. Iliopsoas bursitis and abnormal findings of th... | ['Adult', 'Arthritis, Rheumatoid', 'Bursitis', 'Femoral Neuropathy', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Psoas Muscles'] | 16,622,726 | [['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C05.550.251'], ['C10.668.829.500.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A02.633.567.825']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primary care provider receipt of cardiac rehabilitation discharge summaries: are they getting what they want to promote long-term risk reduction? | BACKGROUND: Communication between cardiac rehabilitation (CR) and primary care providers (PCPs) is paramount to promoting long-term risk reduction after the completion of CR. The objectives of this study were to investigate receipt of CR discharge summaries by PCPs, as well as timing, and satisfaction with and percepti... | ['Communication', 'Continuity of Patient Care', 'Cross-Sectional Studies', 'Data Collection', 'Female', 'Heart Diseases', 'Humans', 'Interprofessional Relations', 'Male', 'Middle Aged', 'Ontario', 'Patient Discharge', 'Physicians, Primary Care', 'Process Assessment, Health Care', 'Prospective Studies', 'Rehabilitation ... | 23,300,269 | [['F01.145.209', 'L01.143'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ... | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
PTBP1 | Polypyrimidine tract-binding proteins (PTBPs) are RNA binding proteins that regulate a number of posttranscriptional events. Human PTBP1 transits between the nucleus and cytoplasm and is thought to regulate RNA processes in both. However, information about PTBP1 mRNA isoforms and regulation of PTPB1 expression remains ... | ["3' Untranslated Regions", "5' Untranslated Regions", 'HEK293 Cells', 'Heterogeneous-Nuclear Ribonucleoproteins', 'Humans', 'Polypyrimidine Tract-Binding Protein', 'Protein Biosynthesis', 'RNA Isoforms', 'RNA, Messenger'] | 31,263,002 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['A11.251.210.172.750', 'A11.436.334'], ['D12.776.157.725.813.750', 'D12.77... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of norfloxacin for shigellosis: a double-blind randomised clinical trial. | In a double-blind, randomised, clinical trial on 122 adults with acute Shigella dysentery, 60 patients were treated with norfloxacin and 62 with nalidixic acid. Of these, 32 patients in the norfloxacin group and 28 patients in the nalidixic acid group had Shigella in their stool. Patients of the two treatment groups we... | ['Adult', 'Double-Blind Method', 'Dysentery, Bacillary', 'Humans', 'Male', 'Nalidixic Acid', 'Norfloxacin', 'Shigella'] | 1,430,968 | [['M01.060.116'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.612.500', 'D03.633.100.810.835.830.500'], ['D03.633.100.810.835.322.374'], ['B... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Magnetic Particle Imaging (MPI): Experimental Quantification of Vascular Stenosis Using Stationary Stenosis Phantoms. | Magnetic Particle Imaging (MPI) is able to provide high temporal and good spatial resolution, high signal-to-noise ratio and sensitivity. Furthermore, it is a truly quantitative method as its signal strength is proportional to the concentration of its tracer, superparamagnetic iron oxide nanoparticles (SPIOs). Because ... | ['Constriction, Pathologic', 'Diagnostic Imaging', 'Humans', 'Magnetite Nanoparticles', 'Phantoms, Imaging', 'Signal-To-Noise Ratio'] | 28,056,102 | [['C23.300.287'], ['E01.370.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.512.600.500.144.500'], ['E07.671'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia-inducible factor 1á/hedgehog pathway under hypoxia. | Microenvironmental hypoxia-mediated drug resistance is responsible for the failure of cancer therapy. To date, the role of the hedgehog pathway in resistance to temozolomide (TMZ) under hypoxia has not been investigated. In this study, we discovered that the increasing hypoxia-inducible factor 1á (HIF-1á) activated the... | ['Animals', 'Brain Neoplasms', 'Cell Movement', 'Cell Proliferation', 'Flavonoids', 'Gene Expression Regulation, Neoplastic', 'Glioma', 'Hedgehog Proteins', 'Humans', 'Hypoxia', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Rats', 'Signal Transduction', 'Temozolomide', 'Tumor Microenvironment'] | 30,790,292 | [['B01.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G05.308.370'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['D12.644.276.671',... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interoceptive accuracy predicts nonplanning trait impulsivity. | Influential theories concerning personality argue that many impulsive individuals show physiological underarousal at rest. This interoceptive state is proposed to be egodystonic, motivating impulsive maladaptive actions to enhance arousal. However, there is little empirical research on this matter. The current study te... | ['Adolescent', 'Adult', 'Arousal', 'Electrocardiography', 'Female', 'Galvanic Skin Response', 'Heart Rate', 'Humans', 'Impulsive Behavior', 'Interoception', 'Male', 'Personality', 'Young Adult'] | 30,702,155 | [['M01.060.057'], ['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.527'], ['F02.463.593.465'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of submission form characteristics on clinical information received in biopsy accession. | Clinical information supplied to diagnostic laboratories through biopsy submission forms is crucial to accurate, timely diagnosis and to clinicopathologic correlation between microscopic findings and the clinical condition of the patient. The current study attempts to quantify the prevalence of deficient and inadequate... | ['Animals', 'Biopsy', 'Laboratories', 'Pathology, Surgical', 'Practice Guidelines as Topic', 'Records', 'Specimen Handling', 'Veterinary Medicine'] | 22,977,112 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['J03.520', 'N02.278.487'], ['H02.403.650.510'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E05.318.308.940', 'L01.399.250.900', 'N04.452.859', 'N05.715.360.300... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma. | UNLABELLED: Functionalized fullerenes represent a new class of photosensitizer (PS) that is being investigated for photodynamic therapy (PDT) of various diseases, including cancer. We tested the hypothesis that fullerenes could be used to mediate PDT of intraperitoneal (IP) carcinomatosis in a mouse model. In humans th... | ['Abdomen', 'Adenocarcinoma', 'Animals', 'Cell Line, Tumor', 'Colonic Neoplasms', 'Fullerenes', 'Humans', 'Injections, Intraperitoneal', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Micelles', 'Peritoneum', 'Photochemotherapy', 'Photosensitizing Agents', 'Pyrrolidines'] | 21,645,643 | [['A01.923.047'], ['C04.557.470.200.025'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D01.268.150.250', 'J01.637.512.600.612.350'], ['B01.050.150.900.649.313.988.400.1... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Molecular characterization of Staphylococcus aureus carrying the panton-valentine leucocidin genes in northern Spain. | OBJECTIVES: To study the prevalence of the Panton-Valentine leucocidin (PVL) gene in methicillin-susceptible (MSSA) and methicillin-resistant (MRSA) Staphylococcus aureus obtained in Gipuzkoa, northeastern area of the Basque Country, north-central Spain, and perform the molecular characterization of PVL-positive isolat... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bacterial Toxins', 'Child', 'Child, Preschool', 'DNA, Bacterial', 'Exotoxins', 'Humans', 'Infant', 'Leukocidins', 'Male', 'Middle Aged', 'Molecular Epidemiology', 'Molecular Typing', 'Polymerase Chain Reaction', 'Spain', 'Staphylococcal Infections', 'Staphylococcus ... | 22,080,089 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.946.123'], ['M01.060.406'], ['M01.060.406.448'], ['D13.444.308.212'], ['D23.946.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D12.776.543.695.750'], ['M01.060.116.630'], ['E05.318.416', 'E05.393.522', 'H0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
In vivo MR acoustic radiation force imaging in the porcine liver. | PURPOSE: High intensity focused ultrasound (HIFU) in the abdomen can be sensitive to acoustic aberrations that can exist in the beam path of a single sonication. Having an accurate method to quickly visualize the transducer focus without damaging tissue could assist with executing the treatment plan accurately and pred... | ['Animals', 'Calibration', 'Elasticity Imaging Techniques', 'Liver', 'Magnetic Resonance Imaging', 'Phantoms, Imaging', 'Respiration', 'Swine', 'Thermometers'] | 21,978,053 | [['B01.050'], ['E05.978.155'], ['E01.370.350.850.270'], ['A03.620'], ['E01.370.350.825.500'], ['E07.671'], ['G09.772.705'], ['B01.050.150.900.649.313.500.880'], ['E07.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pramipexole in progressive supranuclear palsy. | Progressive supranuclear palsy (PSP) is a progressive neurodegenerative disorder with no effective treatment. Dopaminergic agents occasionally produce transient symptomatic improvement. The authors report the results of pramipexole treatment (4.5 mg daily) in six patients with PSP (average disease duration, 4.4 years).... | ['Aged', 'Benzothiazoles', 'Dopamine Agonists', 'Humans', 'Pilot Projects', 'Pramipexole', 'Supranuclear Palsy, Progressive', 'Thiazoles'] | 10,078,747 | [['M01.060.116.100'], ['D03.383.129.708.089', 'D03.633.100.185'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['D03.383.129.708.089.514', 'D03.633.100.185.514'], ['C10.228.140.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Seizures and stupor during intravenous mannose therapy in a patient with CDG syndrome type 1b (MPI-CDG). | MPI-CDG (formally called CDG 1b), caused by phosphomannose isomerase (MPI) deficiency, leads to hypoglycaemia, protein losing enteropathy, hepatopathy, and thrombotic events, whereas neurologic development remains unaffected. Dietary supplementation of mannose can reverse clinical symptoms by entering the N-glycosylati... | ['Adenosine Triphosphate', 'Biomarkers', 'Blood Glucose', 'Congenital Disorders of Glycosylation', 'Electroencephalography', 'Energy Metabolism', 'Genetic Predisposition to Disease', 'Glucose', 'Humans', 'Infusions, Intravenous', 'Injections, Intravenous', 'Magnetic Resonance Imaging', 'Male', 'Mannose', 'Mannose-6-Pho... | 21,240,668 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D23.101'], ['D09.947.875.359.448.500'], ['C16.320.565.202.125', 'C18.452.648.202.125'], ['E01.370.376.300', 'E01.370.405.245'], ['G03.295'], ['C23.550.291.687.500', 'G05.380.355'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.40... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Utility of mechanism-of-injury-based assessment and treatment: Blast Injury Program case illustration. | While medicine typically proceeds in a sequential fashion based on primary symptoms, sometimes relying on a parallel, mechanism-of-injury-based approach is advantageous, particularly when the mechanism of injury is associated with a variety of known sequelae. A mechanism-of-injury-based approach relies on knowledge of ... | ['Adult', 'Aged, 80 and over', 'Blast Injuries', 'Brain Injuries', 'Florida', 'Humans', 'Iraq', 'Male', 'Medical History Taking', 'Military Medicine', 'Multiple Trauma', 'Process Assessment, Health Care', 'United States', 'United States Department of Veterans Affairs', 'Veterans', 'Warfare'] | 16,320,137 | [['M01.060.116'], ['M01.060.116.100.080'], ['C26.120.126'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['Z01.107.567.875.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.360'], ['E01.370.510'], ['H02.403.500'], ['C26.640'], ['N04.761.559.650', 'N05.715.360.575.625'], ['Z01.1... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Molecular discrimination between Campylobacter jejuni, Campylobacter coli, Campylobacter lari and Campylobacter upsaliensis by polymerase chain reaction based on a novel putative GTPase gene. | Polymerase chain reaction (PCR) mediated DNA fingerprinting has resulted in the identification of a novel Campylobacter jejuni gene, encoding a GTPase protein. The gene, consisting of 383 amino acids contained semi-conserved GTP-binding sites (designated G-1 to G-4), that are characteristic for members of the GTPase pr... | ['Amino Acid Sequence', 'Base Sequence', 'Blotting, Southern', 'Campylobacter', 'Campylobacter coli', 'Campylobacter jejuni', 'DNA Primers', 'DNA Probes', 'DNA, Bacterial', 'GTP Phosphohydrolases', 'Genes, Bacterial', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sequence Analysis', 'Species Specificity'] | 9,232,616 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['B03.440.180', 'B03.660.150.235.250.500'], ['B03.440.180.200', 'B03.660.150.235.250.500.100'], ['B03.440.180.425', 'B03.660.150.235.250.500.375'], ['D13.695.578... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Surgical corneal light occluder made of black HEMA. | A safe, simple surgical light occluder made of black pigmented hydrated HEMA is described. It protects the retina from all wavelengths of light and protects the corneal epithelium against abrasion and opacities due to drying during surgery. | ['Acrylates', 'Cornea', 'Eye Diseases', 'Eye Injuries', 'Eye Protective Devices', 'Humans', 'Light', 'Methacrylates', 'Protective Devices', 'Retina'] | 4,080,304 | [['D02.241.081.069'], ['A09.371.060.217'], ['C11'], ['C10.900.300.284.250', 'C11.297', 'C26.915.300.425.250'], ['J01.637.708.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02.241.081.069.600'], ['E07.700', 'J01.637.708'], ['A0... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Factors Associated With Waiting Time for Breast Cancer Treatment in a Teaching Hospital in Ghana. | Background Breast cancer is the leading cause of cancer-related mortality among women in Ghana. Data are limited on the predictors of poor outcomes in breast cancer patients in low-income countries; however, prolonged waiting time has been implicated. Among breast cancer patients who received treatment at Korle Bu Teac... | ['Adult', 'Aged', 'Breast Neoplasms', 'Delivery of Health Care', 'Female', 'Ghana', 'Hospitals, Teaching', 'Humans', 'Insurance, Health', 'Middle Aged', 'Neoplasm Staging', 'Regression Analysis', 'Retrospective Studies', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Time-to-Treatment', 'Waiting Lists'] | 27,091,222 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['N04.590.374', 'N05.300'], ['Z01.058.290.190.320'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['M01.060.116.630'], ['E01.789.625'], ['E05.318.740.750', 'N05.715.360.750.695... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Maintenance of undifferentiated state and self-renewal of embryonic neural stem cells by Polycomb protein Ring1B. | Cell lineages generated during development and tissue maintenance are derived from self-renewing stem cells by differentiation of their committed progeny. Recent studies suggest that epigenetic mechanisms, and in particular the Polycomb group (PcG) of genes, play important roles in controlling stem cell self-renewal. H... | ['Animals', 'Blotting, Western', 'Cell Differentiation', 'Cells, Cultured', 'Cyclin-Dependent Kinase Inhibitor p21', 'Embryonic Stem Cells', 'Mice', 'Neurons', 'Olfactory Bulb', 'Oligonucleotide Array Sequence Analysis', 'Polycomb Repressive Complex 1', 'Repressor Proteins', 'Reverse Transcriptase Polymerase Chain Reac... | 19,544,461 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.152'], ['A11.251'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['A11.872.700.250'], ['B01.050.150.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serotonergic neurotransmission in the ventral hippocampus is enhanced by corticosterone and altered by chronic amphetamine treatment. | The ventral hippocampus modulates anxiety-like behavior in rats, and serotonergic transmission within the hippocampus facilitates adaptation to stress. Chronic amphetamine treatment results in anxiety-like behavior in rats and reduced monoamine concentrations in the ventral hippocampus. Since reduced hippocampal seroto... | ['Amphetamines', 'Animals', 'Anti-Inflammatory Agents', 'CA1 Region, Hippocampal', 'Central Nervous System Stimulants', 'Corticosterone', 'Disease Models, Animal', 'Drug Administration Schedule', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Serotonin', 'Synaptic Transmission'] | 21,420,472 | [['D02.092.471.683.152'], ['B01.050'], ['D27.505.954.158'], ['A08.186.211.180.405.099', 'A08.186.211.200.885.287.500.345.099'], ['D27.505.696.282', 'D27.505.954.427.220'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.283'], ['B01.050.150.900.649.31... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[ENDOSCOPIC MUCOSAL RESECTION AND ENDOSCOPIC DISSECTION IN THE SUBMUCOSAL LAYER FOR EARLY GASTRIC CANCER]. | The development of endoscopic techniques of surgery of patients with early gastric cancer (high and moderately differentiated adenocarcinoma) by endoscopic mucosal resection and endoscopic submucosal dissection with regard to their minimally invasion, high efficiency and quality of life after treatment allowed seriousl... | ['Adenocarcinoma', 'Adult', 'Aged', 'Endosonography', 'Female', 'Gastric Mucosa', 'Gastroscopy', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Stomach Neoplasms', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 26,242,153 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.850.280'], ['A03.556.875.875.440', 'A10.615.550.291'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.8... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
CT findings in pediatric gastrointestinal ascariasis. | We present a case of a 9-yr-old child with gastrointestinal ascariasis. Computed tomography of the abdomen demonstrates the Ascaris roundworms as cylindrical filling defects within contrast filled bowel loops. In addition, the intestinal tract of the roundworm itself is seen as a thin thread of oral contrast within the... | ['Abdominal Pain', 'Animals', 'Antinematodal Agents', 'Ascariasis', 'Ascaris lumbricoides', 'Child', 'Female', 'Humans', 'Intestinal Diseases', 'Mebendazole', 'Radiographic Image Enhancement', 'Tomography, X-Ray Computed'] | 9,118,070 | [['C23.888.592.612.054', 'C23.888.821.030'], ['B01.050'], ['D27.505.954.122.250.075.080'], ['C01.610.335.508.700.100.070'], ['B01.050.500.500.294.400.500.100.108.425'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469'], ['D02.241.081.251.415', 'D03.633.100.103.600'], ['E01.370.350.600.35... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A novel function for Myc: inhibition of C/EBP-dependent gene activation. | We have investigated the effect of the v-Myc oncoprotein on gene expression in myelomonocytic cells. We find that v-Myc dramatically down-regulates the expression of myelomonocytic-specific genes, such as the chicken mim-1 and lysozyme genes, both of which are known targets for C/EBP transcription factors. We present e... | ['Acetyltransferases', 'Animals', 'CCAAT-Enhancer-Binding Proteins', 'Cell Line', 'Chickens', 'DNA-Binding Proteins', 'Down-Regulation', 'Gene Expression Regulation', 'Muramidase', 'Nuclear Proteins', 'Oncogene Protein p55(v-myc)', 'Proteins', 'Quail', 'Transcriptional Activation'] | 8,692,870 | [['D08.811.913.050.134'], ['B01.050'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['A11.251.210'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D12.776.260'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.308'], ['D08.811.277.450.642'], ['D12.776.660'], ['D12.776.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical crown lengthening in the esthetic zone. | Periodontal surgical procedures consisting of gingival flaps and osseous recontouring are indicated for crown lengthening of several contiguous teeth in the esthetic zone; both in cases where restorations are required and in cases where no restorations are planned, such as in patients with excessive gingival display du... | ['Alveolectomy', 'Alveoloplasty', 'Crown Lengthening', 'Cuspid', 'Decision Trees', 'Dental Restoration, Permanent', 'Esthetics, Dental', 'Gingiva', 'Gingivectomy', 'Gingivoplasty', 'Humans', 'Incisor', 'Orthodontic Extrusion', 'Patient Care Planning', 'Surgical Flaps', 'Wound Healing'] | 17,915,591 | [['E04.545.550.110', 'E06.645.550.110'], ['E04.545.550.120', 'E06.645.550.120'], ['E06.323.115', 'E06.658.578.099'], ['A14.549.167.860.200'], ['G17.162.500'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['E06.420'], ['A14.549.167.646.480'], ['E04.545.350', 'E06.645.350', 'E06.721.321'], ['E04.545.355', 'E06.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Psychological impact of burn scars on quality of life in patients with extensive burns who received allotransplant. | With the remarkable progress in the field of burns treatment, the outcome of extensive burns improved significantly. The increased likelihood of survival of a burn victim heightens concerns for potential psychological morbidity for the survivors. Hypertrophic scarring is devastating and can result in disfigurement that... | ['Adult', 'Burns', 'Cicatrix', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Retrospective Studies', 'Surveys and Questionnaires', 'Survivors', 'Transplantation, Autologous', 'Transplantation, Homologous', 'Young Adult'] | 22,990,550 | [['M01.060.116'], ['C26.200'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Secondary malignancies after rectal cancer resection with and without radiation therapy: A propensity-adjusted, population-based SEER analysis. | BACKGROUND: The relationship between radiation therapy for rectal cancer and secondary malignancies is debated. The present study is the first population-based analysis using conventional multivariable analyses as well as propensity score matching to assess this relationship.METHODS: Overall, 77,484 patients after rese... | ['Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms, Second Primary', 'Propensity Score', 'Proportional Hazards Models', 'Prostatic Neoplasms', 'Rectal Neoplasms', 'SEER Program', 'Urinary Bladder Neoplasms'] | 28,285,840 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.692'], ['E05.318.740.600.675', 'N05.715.360.750.625.620', 'N06.850.520.830.600.650'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.599.835.900',... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Optimization of extraction procedure of psammosilene tunicoides by uniform design with pharmacodynamic index]. | OBJECTIVE: For anti-inflammation, relieving pain and decreasing acute toxicity, the best condition for extracting procedure of Psammosilene tunicoides was chosen. And the relationships between several solvent extracts and pharmacodynamic index were studied.METHOD: Uniform design with multi-targets was used in the optim... | ['Animals', 'Caryophyllaceae', 'Drugs, Chinese Herbal', 'Female', 'Inflammation', 'Lethal Dose 50', 'Male', 'Mice', 'Pain', 'Random Allocation'] | 19,007,005 | [['B01.050'], ['B01.650.940.800.575.912.250.198.500.250'], ['D20.215.784.500.350', 'D26.335'], ['C23.550.470'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E05.318.370.700', 'E05.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of rolipram, a selective inhibitor of type 4 phosphodiesterase, on lipopolysaccharide-induced uveitis in rats. | PURPOSE: To investigate effects of rolipram, an inhibitor of type 4 phosphodiesterase, on lipopolysaccharide (LPS)-induced uveitis in Wistar rats.METHODS: A total of 100 microg LPS was injected into the rat footpad. Rolipram (Wako Pure Chemical, Osaka, Japan) was injected intraperitoneally 30 minutes before administrat... | ["3',5'-Cyclic-AMP Phosphodiesterases", 'Animals', 'Aqueous Humor', 'Ciliary Body', 'Cyclic Nucleotide Phosphodiesterases, Type 4', 'E-Selectin', 'Escherichia coli', 'Immunoenzyme Techniques', 'Injections, Intraperitoneal', 'Interleukin-6', 'Iris', 'Lipopolysaccharides', 'Male', 'NF-kappa B', 'Nitric Oxide Synthase', '... | 15,277,469 | [['D08.811.277.352.640.150', 'D12.644.360.008', 'D12.776.476.008'], ['B01.050'], ['A09.371.060.067.070', 'A12.207.270.040'], ['A09.371.060.160', 'A09.371.894.280'], ['D08.811.277.352.640.150.400', 'D12.644.360.008.400', 'D12.776.476.008.400'], ['D12.776.395.550.200.700.300', 'D12.776.503.843.300', 'D12.776.543.550.200.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of bcl-2 in reactive and neoplastic astrocytes: lack of correlation with presence or degree of malignancy. | The bcl-2 protooncogene encodes a 26-kD protein that extends cell survival by blocking apoptosis. This protein has been found to be overexpressed in neoplastic neural cell lines, although its expression in reactive and neoplastic astrocytes in vivo has not been well characterized. The authors hypothesized that bcl-2 on... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Apoptosis', 'Astrocytes', 'Astrocytoma', 'Cell Count', 'Female', 'Gene Expression Regulation, Neoplastic', 'Glioblastoma', 'Glioma', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-bcl-2', 'Proto-Oncogenes'] | 7,490,615 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G04.146.954.035'], ['A08.637.200', 'A11.650.200'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cells. | Hammerhead ribozymes were expressed under the control of similar tRNA promoters, localizing transcripts either in the cytoplasm or the nucleus. The tRNA(Val)-driven ribozyme (tRNA-Rz; tRNA with extra sequences at the 3' end) that has been used in our ribozyme studies was exported efficiently into the cytoplasm and ribo... | ['Base Sequence', 'Biological Transport', 'Cell Nucleus', 'Cytoplasm', 'Genetic Engineering', 'HeLa Cells', 'Humans', 'In Situ Hybridization', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Promoter Regions, Genetic', 'RNA Polymerase III', 'RNA, Catalytic', 'RNA, Messenger', 'RNA, Small Nuclear', 'RNA, Transf... | 11,433,023 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G03.143'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214'], ['E05.393.420'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Technical note: A simplified PCR-based assay for the characterization of two prolactin variants that affect milk traits in sheep breeds. | In the present study, a rapid and cost-effective PCR-based assay was developed for the genetic identification of 2 different variants within intron 2 of the prolactin gene. This polymorphism has previously been associated with milk traits in some ovine breeds and was recently proposed as a potential marker for future b... | ['Animals', 'Genotype', 'Introns', 'Lactation', 'Milk', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Polymorphism, Restriction Fragment Length', 'Prolactin', 'Reproducibility of Results', 'Sheep'] | 21,094,774 | [['B01.050'], ['G05.380'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['G08.686.523', 'G08.686.702.500'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['E05.393.620.500'], ['G05.365.795'], ['G05.365.795.595'], ['D06.472.699.322.576.773', 'D06.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells. | Resveratrol has been shown to possess antioxidant and anticancer activities, but little is known on the effect of resveratrol derivatives. Recently we have isolated resveratrol and its dimers and trimers from peony (Paeonia lactiflora) seeds, and reported their strong antioxidant and cytotoxic activity. In the present ... | ['Apoptosis', 'Aryl Hydrocarbon Hydroxylases', 'Cell Cycle', 'Cytochrome P-450 CYP1B1', 'Cytochrome P-450 Enzyme System', 'Flow Cytometry', 'Gene Expression Regulation, Neoplastic', 'HL-60 Cells', 'Humans', 'Leukemia', 'RNA, Messenger', 'Resveratrol', 'Stilbenes'] | 14,749,523 | [['G04.146.954.035'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G04.144'], ['D08.244.453.005.500', 'D08.244.453.100.875', 'D08.811.682.690.708.170.010.500', 'D08.811.682.690.708.170.020.875', 'D12.776.422.220.453.010.500', 'D12.776.422.220.453.100.875'], ['D08.244.453', 'D08.811.6... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Significance of the upright T wave in precordial lead V1 in adults with coronary artery disease. | To determine the prevalence and evaluate the significance of an upright T wave in precordial lead V1, the 12 lead electrocardiograms of 218 patients undergoing diagnostic catheterization for the evaluation of chest pain were reviewed. Of this total, 184 patients had severe coronary artery disease (greater than or equal... | ['Adult', 'Aged', 'Coronary Disease', 'Electrocardiography', 'Female', 'Heart', 'Humans', 'Male', 'Middle Aged'] | 6,833,662 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rule-based and information-integration category learning in normal aging. | The basal ganglia and prefrontal cortex play critical roles in category learning. Both regions evidence age-related structural and functional declines. The current study examined rule-based and information-integration category learning in a group of older and younger adults. Rule-based learning is thought to involve ex... | ['Adolescent', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Basal Ganglia', 'Female', 'Humans', 'Learning', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Models, Psychological', 'Neuropsychological Tests', 'Prefrontal Cortex', 'Young Adult'] | 20,547,171 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['A08.186.211.200.885.287.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540.407'], ['M01.060.116.630'], ['E05.599.695'], ['F04.711.513'], [... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Techniques for fast stereoscopic MRI. | Stereoscopic MRI can impart 3D perception with only two image acquisitions. This economy over standard multiplanar 3D volume renderings allows faster frame rates, which are needed for real-time imaging applications. Real-time 3D perception may enhance the appreciation of complex anatomical structures, and may improve h... | ['Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Mathematics', 'Neck', 'Phantoms, Imaging'] | 11,477,636 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500'], ['H01.548'], ['A01.598'], ['E07.671']] | ['Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Complete sleep and local field potential analysis regarding estrus cycle, pregnancy, postpartum and post-weaning periods and homeostatic sleep regulation in female rats. | Sleep and local field potential (LFP) characteristics were addressed during the reproductive cycle in female rats using long-term (60-70 days) recordings. Changes in homeostatic sleep regulation was tested by sleep deprivation (SDep). The effect of mother-pup separation on sleep was also investigated during the postpar... | ['Animals', 'Estrus', 'Female', 'Homeostasis', 'Postpartum Period', 'Pregnancy', 'Rats', 'Sleep', 'Sleep Deprivation', 'Wakefulness', 'Weaning'] | 32,444,809 | [['B01.050'], ['G08.686.195.500'], ['G07.410'], ['G08.686.702'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['F02.830.855', 'G11.561.803'], ['C10.886.425.175', 'C23.888.592.796.772', 'F02.830.855.671', 'F03.870.400.099'], ['F02.830.104.821', 'G11.561.035.738'], ['G07.203.650.220.500.750', 'G07.20... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical evaluation of prototype high-performance anti-scatter grids: potential for improved digital radiographic image quality. | Grid evaluation for a screen-film x-ray system has typically included independent measurement of the opposing contrast improvement factor and Bucky factor. Neither of these metrics, however, is appropriate when assessing grid performance in a digital imaging environment. For digital radiographic systems, the benefit of... | ['Biophysical Phenomena', 'Humans', 'Phantoms, Imaging', 'Quality Control', 'Radiographic Image Enhancement', 'Scattering, Radiation', 'X-Ray Intensifying Screens'] | 19,098,352 | [['G01.154'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['J01.897.608'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600'], ['E05.196.822', 'G01.867'], ['E07.970']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Survivin--an attractive target for RNAi in non-Hodgkin's lymphoma, Daudi cell line as a model. | RNA interference (RNAi) has been widely used in tumor gene therapy, antivirus and gene drug selection. Survivin gene is highly expressed in non-Hodgkin's lymphoma (NHL) tissues and high malignancy Burkitt's lymphoma cell line-Daudi and it is regarded as a potential target of gene therapy for NHL. This study used a vect... | ['Apoptosis', 'Blotting, Western', 'Burkitt Lymphoma', 'Cell Proliferation', 'Flow Cytometry', 'Gene Silencing', 'Humans', 'Inhibitor of Apoptosis Proteins', 'Microtubule-Associated Proteins', 'Models, Biological', 'Neoplasm Proteins', 'Plasmids', 'RNA, Messenger', 'RNA, Small Interfering', 'Reverse Transcriptase Polym... | 17,065,009 | [['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.50... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigating molecular recognition and biological function at interfaces using piscidins, antimicrobial peptides from fish. | We studied amidated and non-amidated piscidins 1 and 3, amphipathic cationic antimicrobial peptides from fish, to characterize functional and structural similarities and differences between these peptides and better understand the structural motifs involved in biological activity and functional diversity among amidated... | ['Amino Acid Sequence', 'Animals', 'Anti-Infective Agents', 'Circular Dichroism', 'Fishes', 'Hemolysis', 'Molecular Sequence Data', 'Nuclear Magnetic Resonance, Biomolecular', 'Peptides'] | 16,815,244 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.122'], ['E05.196.867.151'], ['B01.050.150.900.493'], ['C23.550.403', 'G12.122.545'], ['L01.453.245.667'], ['E05.196.867.519.550'], ['D12.644']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[A morphological assessment of the efficacy of the deaggregation therapy of chronic catarrhal gingivitis]. | Light optics, electron microscopy, morphometry were used to study the structural changes in the epithelial cells and endotheliocytes of gingival papillary capillaries of patients with chronic catarrhal gingivitis after papaverin therapy. The studies have revealed signs of disappearance of intercellular edema and a high... | ['Chronic Disease', 'Combined Modality Therapy', 'Endothelium', 'Epithelium', 'Evaluation Studies as Topic', 'Gingiva', 'Gingivitis', 'Humans', 'Microscopy, Electron', 'Periodontal Index'] | 1,440,670 | [['C23.550.291.500'], ['E02.186'], ['A10.272.491'], ['A10.272'], ['E05.337', 'N05.715.360.335'], ['A14.549.167.646.480'], ['C01.408', 'C07.465.714.258.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['E05.318.308.980.438.300.725', 'E06.208.720', 'E06.721.658', 'N05.715.36... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Diffuse muscular hypertrophy of esophagus. | Six cases of diffuse muscular hypertrophy of the esophagus are reported. The clinical diagnosis is often missed and may be confused with achalasia. Some clinical features that help distinguish this disease are a sensation of "grasping" any tube or instrument introduced into the esophagus, marked sustained elevation in ... | ['Aged', 'Diabetes Complications', 'Diagnosis, Differential', 'Dilatation, Pathologic', 'Esophageal Achalasia', 'Esophagus', 'Female', 'Humans', 'Hypertrophy', 'Male', 'Middle Aged', 'Muscle, Smooth'] | 3,706,372 | [['M01.060.116.100'], ['C19.246.099'], ['E01.171'], ['C23.300.325'], ['C06.405.117.119.500.432'], ['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['M01.060.116.630'], ['A02.633.570', 'A10.690.467']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preliminary study of a robotic foot-ankle prosthesis with active alignment. | Robotic prosthetic foot-ankle prostheses typically aim to replace the lost joint with revolute joints aimed at replicating normal joint biomechanics. In this paper, a previously developed robotic ankle prosthesis with active alignment is evaluated. It uses a four-bar mechanism to inject positive power into the gait cyc... | ['Ankle', 'Artificial Limbs', 'Biomechanical Phenomena', 'Foot', 'Humans', 'Joint Prosthesis', 'Male', 'Prosthesis Design', 'Robotics'] | 28,814,000 | [['A01.378.610.050'], ['E07.695.050', 'E07.858.082.050', 'E07.858.442.050'], ['G01.154.090', 'G01.374.089'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400'], ['E05.320.550', 'E07.695.680'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Simulated microgravity exposure modulates the phenotype of cultured vascular smooth muscle cells. | Evidence from ground-based animal studies using tail-suspended hindlimb unloaded rats model has clearly demonstrated that simulated microgravity-induced smooth muscle cell phenotype conversion, a characteristic vascular structural and functional remodeling, may be one of the key contributors to postspaceflight orthosta... | ['Animals', 'Aorta', 'Apoptosis', 'Biomarkers', 'Biomechanical Phenomena', 'Cell Movement', 'Cell Proliferation', 'Cells, Cultured', 'Gene Expression Regulation', 'Male', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'Nitric Oxide', 'Phenotype', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Stress Fibers'... | 23,097,024 | [['B01.050'], ['A07.015.114.056'], ['G04.146.954.035'], ['D23.101'], ['G01.154.090', 'G01.374.089'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G05.308'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['A11.620.520'], ['D01.339.387', 'D01.625.550.500', 'D01.625.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Polypeptide pattern of human breast epithelial cells following human chorionic gonadotropin (hCG) treatment. | Numerous attempts have made to describe the particular protein pattern of malignant cells by using high resolution two-dimensional polyacrylamide gel electrophoresis (2-D PAGE). The placental hormone human chorionic gonadotropin (hCG) inhibits tumor initiation and progression in experimental animals and has an inhibito... | ['Breast', 'Cell Division', 'Cell Line', 'Cell Survival', 'Chorionic Gonadotropin', 'Electrophoresis, Gel, Two-Dimensional', 'Epithelial Cells', 'Epithelium', 'Female', 'Humans', 'Immunohistochemistry', 'Peptides', 'Prostatic Secretory Proteins', 'Protein Biosynthesis', 'RNA, Messenger'] | 7,925,253 | [['A01.236'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['G04.346'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['E05.196.401.250', 'E05.301.300.230'], ['A11.436'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cachexia-anorexia-asthenia. | The National Cancer Institute (Canada) sponsored a workshop on symptom control in Banff, Alberta, in October 1993. This article reports on the workshop recommendations for research on one symptom complex, the cachexia-anorexia-asthenia syndrome. In addition to encouraging study generation, the recommendations provide a... | ['Anorexia', 'Asthenia', 'Cachexia', 'Humans', 'Neoplasms', 'Research', 'Syndrome'] | 7,730,686 | [['C23.888.821.108'], ['C23.888.089'], ['C23.888.144.243.963.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['H01.770.644'], ['C23.550.288.500']] | ['Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Decatenation of kinetoplast DNA by topoisomerases. | Kinetoplast DNA is the mitochondrial DNA of trypanosomatids such as Crithidia fasciculata. This DNA is in the form of networks containing thousands of DNA circles which are apparently catenated (interlocked). Some topoisomerases, such as T4 phage topoisomerase and DNA gyrase, catalyze a decatenation of the networks to ... | ['Animals', 'Crithidia', 'DNA', 'DNA Topoisomerases, Type II', 'DNA, Circular', 'Microscopy, Electron', 'Subcellular Fractions', 'T-Phages'] | 6,246,090 | [['B01.050'], ['B01.268.475.868.110'], ['D13.444.308'], ['D08.811.399.403.741'], ['D13.444.308.283', 'G02.111.570.820.486.212', 'G05.360.580.156'], ['E01.370.350.515.402', 'E05.595.402'], ['A11.284.835'], ['B04.123.205.891']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Animal model for colorectal cancer. | The development of a satisfactory rodent model for cancer of the large intestine began with the discovery by Laqueur and associates in 1962 that the plant product, cycasin (methylazoxymethanol glycoside), is a potent carcinogen for rodents. Soon after that, DMH, AOM, and MAM were found to be even more efficient intesti... | ['Adenoma', 'Animals', 'Carcinogens', 'Carcinoma', 'Colonic Neoplasms', 'Mice', 'Neoplasms, Experimental', 'Ornithine Decarboxylase', 'Rats', 'Rectal Neoplasms', 'Risk'] | 4,034,597 | [['C04.557.470.035'], ['B01.050'], ['D27.888.569.100'], ['C04.557.470.200'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.619', 'E05.598.500.496'], ['D08.811.520.224.125.425... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Epididymo-orchitis due to Pseudomonas pseudomallei. | We report the first case of epididymo-orchitis caused by Pseudomonas pseudomallei. The diagnosis was made by isolation of the organism from testicle pus and urine. Treatment was successful with chloramphenicol and co-trimoxazole. | ['Adult', 'Epididymitis', 'Humans', 'Male', 'Melioidosis', 'Orchitis'] | 6,887,385 | [['M01.060.116'], ['C12.294.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.170.531'], ['C12.294.829.493', 'C19.391.829.493']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of a 300 mT static magnetic field on human umbilical vein endothelial cells. | This study describes the effects of a static magnetic field (SMF) on cell growth and DNA integrity of human umbilical vein endothelial cells (HUVECs). Fast halo assay was used to investigate nuclear damage; quantitative polymerase chain reaction (QPCR), standard PCR, and real-time PCR were used to evaluate mitochondria... | ['Cell Nucleus', 'Cell Proliferation', 'DNA Damage', 'DNA, Mitochondrial', 'Endothelial Cells', 'Humans', 'Magnetics', 'Mitochondria', 'Polymerase Chain Reaction', 'Reactive Oxygen Species', 'Rhodamines', 'Time Factors', 'Umbilical Veins'] | 20,623,760 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.200'], ['D13.444.308.283.225'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.671.493'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['E05.393.620.500'], ['D01.339.431', 'D01.650.775'], [... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
ERP correlates of feedback and reward processing in the presence and absence of response choice. | The feedback negativity is a component of the event-related brain potential that is elicited by feedback stimuli associated with unfavorable outcomes. The present research investigated whether this component reflects an evaluation of the valence of experienced outcomes or a process of learning about actions that led to... | ['Adolescent', 'Adult', 'Brain', 'Choice Behavior', 'Decision Making', 'Diagnosis, Computer-Assisted', 'Electroencephalography', 'Event-Related Potentials, P300', 'Feedback', 'Female', 'Gambling', 'Humans', 'Male', 'Psychomotor Performance', 'Reinforcement, Psychology', 'Reward', 'Risk-Taking', 'Statistics as Topic'] | 15,319,308 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['F02.463.785.373.346'], ['F02.463.785.373'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.350', 'G11.561.200.500.350'], ['L01.906.394.211'], ['F01.145.722.408', 'F03.250.400'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Streptokinase resistance test in patients with streptococcal infection and/or high antistreptolysin titers. | The streptokinase resistance test (SRT) has been studied in a group of patients with recent streptococcal infection and/or titres of antistreptolysin higher than 625 units. These patients generally had a higher SRT. | ['Adolescent', 'Adult', 'Aged', 'Antibodies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Streptococcal Infections', 'Streptokinase', 'Streptolysins'] | 1,257,700 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.150.252.410.890'], ['D08.811.277.656.300.775', 'D12.776.124.125.662.537'], ['D12.776.543.695.937', 'D23.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Parent and physician perceptions of medical home care for children with autism spectrum disorders in the state of Kentucky. | The medical home model of care is widely accepted as the ideal for children with autism spectrum disorders (ASDs) but may be very difficult to implement. In this study, parents of children with autism and pediatricians caring for children with autism in Kentucky were surveyed to determine the current status of primary ... | ['Adolescent', 'Adult', 'Child', 'Child Development Disorders, Pervasive', 'Child, Preschool', 'Education, Medical, Continuing', 'Female', 'Health Care Surveys', 'Health Resources', 'Health Services Needs and Demand', 'Humans', 'Kentucky', 'Male', 'Parents', 'Patient-Centered Care', 'Physicians', 'Social Perception', '... | 22,984,194 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['F03.625.164'], ['M01.060.406.448'], ['I02.358.212.350', 'I02.358.399.250'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N03.349.340', 'N05.300.420'], ['N03.349.380.420', 'N05.300.450'], ['B01.050... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Systolic blood pressure and short-term mortality in the emergency department and prehospital setting: a hospital-based cohort study. | INTRODUCTION: Systolic blood pressure is a widely used tool to assess circulatory function in acutely ill patients. The systolic blood pressure limit where a given patient should be considered hypotensive is the subject of debate and recent studies have advocated higher systolic blood pressure thresholds than the tradi... | ['Adult', 'Aged', 'Blood Pressure', 'Cohort Studies', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Female', 'Humans', 'Hypotension', 'Logistic Models', 'Male', 'Middle Aged', 'Mortality', 'Prognosis', 'ROC Curve', 'Retrospective Studies', 'Risk', 'Systole'] | 25,888,035 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.514'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pubertal changes in boys and girls in Newcastle upon Tyne. | 669 boys and 753 girls born in 1962 and living at home were observed at approximately half-yearly intervals from 9 to 17 years of age. Mean ages of reaching various developmental stages were calculated for voice change and facial hair in boys, menarche and breast development in girls, and for axillary hair in both sexe... | ['Adolescent', 'Anthropometry', 'Body Height', 'Child', 'England', 'Female', 'Humans', 'Male', 'Menarche', 'Puberty', 'Sex Characteristics', 'Sexual Maturation', 'Social Class'] | 7,259,098 | [['M01.060.057'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['M01.060.406'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.760.410', 'G08.686.841.374.410'], ['G08.686.760'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Anemia, Micronutrient Deficiencies, and Malaria in Children and Women in Sierra Leone Prior to the Ebola Outbreak - Findings of a Cross-Sectional Study. | To identify the factors associated with anemia and to document the severity of micronutrient deficiencies, malaria and inflammation, a nationally representative cross-sectional survey was conducted. A three-stage sampling procedure was used to randomly select children <5 years of age and adult women from households in ... | ['Adult', 'Anemia', 'Anemia, Iron-Deficiency', 'Child, Preschool', 'Cross-Sectional Studies', 'Disease Outbreaks', 'Female', 'Folic Acid Deficiency', 'Hemorrhagic Fever, Ebola', 'Humans', 'Infant', 'Infant, Newborn', 'Inflammation', 'Male', 'Micronutrients', 'Pregnancy', 'Prevalence', 'Rural Population', 'Sierra Leone'... | 27,163,254 | [['M01.060.116'], ['C15.378.071'], ['C15.378.071.196.300', 'C18.452.565.100'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.850.290'], ['C18.654.521.500.133.699.308'], ['C01.925.782.417.415', 'C01.925.782.580.250.400'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Effects of thermosensory aging well demonstrated by cold stimulations with high temporal resolution. | INTRODUCTION: The method of limits (MLi) is the most commonly used paradigm to measure the threshold of thermal stimuli. However, the threshold measured by MLi is dependent on reaction time (RT). Because RT in adults increases with age, the inclusion of RT in the MLi paradigm may result in an overestimation of thermal ... | ['Adult', 'Aged', 'Aging', 'Cold Temperature', 'Female', 'Humans', 'Male', 'Physical Stimulation', 'Reaction Time', 'Sensory Thresholds', 'Thermosensing', 'Young Adult'] | 30,945,307 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.723'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Three-dimensional image-based high-dose-rate interstitial brachytherapy for vaginal cancer. | PURPOSE: To evaluate dosimetric and clinical outcomes of three-dimensional (3D) image-based high-dose-rate (HDR) interstitial brachytherapy (HDRB) in patients with vaginal cancers.METHODS AND MATERIALS: Thirty patients with vaginal cancers were treated with HDRB using Syed-Neblett template. CT scan was done after place... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brachytherapy', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Middle Aged', 'Radiotherapy Dosage', 'Radiotherapy, Computer-Assisted', 'Tomography, X-Ray Computed', 'Vaginal Neoplasms'] | 21,665,553 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.815.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.116.630'], ['E02.815.639'], ['E02.815.635', 'L01.313.500.750.100.710.600'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Species richness of arbuscular mycorrhizal fungi: associations with grassland plant richness and biomass. | Although experiments show a positive association between vascular plant and arbuscular mycorrhizal fungal (AMF) species richness, evidence from natural ecosystems is scarce. Furthermore, there is little knowledge about how AMF richness varies with belowground plant richness and biomass. We examined relationships among ... | ['Biodiversity', 'Biomass', 'Computational Biology', 'DNA, Fungal', 'Genes, Fungal', 'Genes, rRNA', 'Grassland', 'Mycorrhizae', 'Plant Roots', 'Plants', 'Saskatchewan', 'Sequence Analysis, DNA'] | 24,641,509 | [['G16.500.275.157.049', 'N06.230.124.049'], ['G16.500.275.157.100', 'N06.230.124.100'], ['H01.158.273.180', 'L01.313.124'], ['D13.444.308.300'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G05.360.340.024.340.645.750'], ['G16.500.275.157.531', 'N06.230.124.390'], ['A18.400.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Dislocation after hip hemiarthroplasty: anterior versus posterior capsular approach. | Prosthetic dislocation is a devastating complication after hip hemiarthroplasty. Posterior and anterior approaches were compared in 375 patients over a 10-year period to determine the effect of surgical approach on the rate of dislocation at 6-month follow-up. Nine (2.3%) dislocations occurred in the study population--... | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Female', 'Femoral Neck Fractures', 'Hip Dislocation', 'Humans', 'Joint Instability', 'Length of Stay', 'Male', 'Postoperative Complications', 'Prosthesis Failure', 'Retrospective Studies'] | 17,323,636 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['C05.550.518.384', 'C26.289.384', 'C26.531.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['E02.760.400.480', 'N... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long-term complications in adult spinal deformity patients having combined surgery a comparison of primary to revision patients. | STUDY DESIGN: This is a comparison of primary (N = 18) to revision (N = 26) combined (anterior and posterior surgery) adult spinal deformity patients with regard to late (>6 months) complications and radiographic/functional outcomes at a minimum 2-year follow-up.OBJECTIVES: To determine whether revision status increase... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Kyphosis', 'Male', 'Middle Aged', 'Pain Measurement', 'Patient Satisfaction', 'Postoperative Complications', 'Prognosis', 'Pseudarthrosis', 'Radiography', 'Reoperation', 'Risk Factors', 'Scoliosis', 'Time Factors', 'Treatment Outcome'] | 11,317,124 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.800.500'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular characterization and chromosomal localization of DRT (EPHT3): a developmentally regulated human protein-tyrosine kinase gene of the EPH family. | By screening a human fetal brain cDNA expression library using a monoclonal antiphosphotyrosine antibody and by 5' RACE procedures, we have isolated overlapping cDNAs encoding a receptor-type tyrosine kinase belonging to the EPH family, DRT (Developmentally Regulated EPH-related Tyrosine kinase gene). The DRT gene is e... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Brain', 'Carcinoma, Small Cell', 'Cell Line', 'Chromosome Mapping', 'Chromosomes, Human, Pair 1', 'Cloning, Molecular', 'DNA, Complementary', 'Gene Expression Regulation, Developmental', 'Humans', 'Medulloblastoma', 'Molecular Sequence Data', 'Protein-Tyrosine Kinase... | 8,589,679 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['C04.557.470.200.380'], ['A11.251.210'], ['E05.393.183'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Impact of thoracic endovascular aortic repair on radial strain in an ex vivo porcine model. | Objectives: To quantify the impact of thoracic endovascular aortic repair (TEVAR) on radial aortic strain with the aim of elucidating stent-graft-induced stiffening and complications.Methods: Twenty fresh thoracic porcine aortas were connected to a mock circulatory loop driven by a centrifugal flow pump. A high-definit... | ['Animals', 'Aorta, Thoracic', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Disease Models, Animal', 'Elasticity', 'Endovascular Procedures', 'Observer Variation', 'Reproducibility of Results', 'Stents', 'Stress, Mechanical', 'Sus scrofa', 'Swine', 'Tensile Strength'] | 28,043,989 | [['B01.050'], ['A07.015.114.056.372'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G01.374.590'], ['E04.100.814.529', 'E04.502.382'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E05.318.370.725', 'E05.337.851', 'N05.71... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Biopsy for suspected spondylodiscitis. | BACKGROUND: Vertebral biopsy is fundamental in determining whether a spinal lesion is of infectious or neoplastic etiology. Accurate diagnosis is critical for proper medical and/or surgical treatment and consequently for the prognosis of the patient. CT-guided percutaneous spinal biopsy (CTSB) may minimize the risk of ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bacteriological Techniques', 'Biopsy, Needle', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Discitis', 'Female', 'Humans', 'Intervertebral Disc', 'Italy', 'Male', 'Middle Aged', 'Osteomyelitis', 'Predictive Value of Tests', 'Prognosis', 'Prospective Stud... | 22,655,481 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['M01.060... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Gender modulates the aging effects on different patterns of early repolarization. | Distinct patterns of early repolarization (ER) are associated with ventricular fibrillation and arrhythmic death. We evaluated whether gender modulated the aging effects on different ER patterns. We studied manifestations of ER in the anterior, inferior, and lateral leads on standard 12-lead electrocardiography from ma... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Arrhythmias, Cardiac', 'Cross-Sectional Studies', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Sex Factors', 'Young Adult'] | 23,612,859 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['C14.280.067', 'C23.550.073'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Cytologic findings as indications: morphologic and immunohistochemical identification of human brain tissue on the clothing of a murderer]. | A case was described in which a murder was concealed by burning the body. The suspect confessed to committing the crime after being informed that human brain tissue in form of slimy stains as well the same blood group as the victim had been identified on his clothing. Slimy stains (approx. 2 x 3 mm) were identified as ... | ['Blood Stains', 'Brain', 'Clothing', 'Fluorescent Antibody Technique', 'Forensic Medicine', 'Homicide', 'Humans', 'Male'] | 6,385,901 | [['I01.198.780.937.206'], ['A08.186.211'], ['J01.637.215'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['H02.403.330', 'I01.198.780.937'], ['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
Effect of different K+ concentrations on Cryptococcus neoformans phenoloxidase activity. | Melanin synthesis in Cryptococcus neoformans, catalyzed by phenoloxidase activity, is one of the oldest virulence factors known. However, until now, the relationship between melanin production in C. neoformans and its virulence has been poorly understood. Among different chemical compounds only Fe3+ and Cu2+ cations en... | ['Acquired Immunodeficiency Syndrome', 'Animals', 'Bird Diseases', 'Birds', 'Caffeic Acids', 'Cryptococcus neoformans', 'Feces', 'Humans', 'Melanins', 'Monophenol Monooxygenase', 'Pigmentation', 'Potassium', 'Virulence'] | 12,749,580 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['B01.050'], ['C22.131'], ['B01.050.150.900.248'], ['D02.241.223.200.054'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['A12.459'], ['B01.050.150.9... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel splicing mutation of PTCH1 in a Chinese family with nevoid basal cell carcinoma syndrome. | Nevoid basal cell carcinoma syndrome (NBCCS) is a rare autosomal dominant disease characterized by the development of multiple jaw keratocysts and basal cell carcinomas (BCC) and accompanied by diverse phenotypes. The establishment of diagnosis lies on the identification of a heterozygous germline pathogenic variant in... | ['Asian Continental Ancestry Group', 'Basal Cell Nevus Syndrome', 'Carcinoma, Basal Cell', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Patched-1 Receptor', 'Skin Neoplasms'] | 30,997,576 | [['M01.686.508.200'], ['C04.182.089.530.690.150', 'C04.557.470.200.165.150', 'C04.557.470.565.165.150', 'C04.700.175', 'C05.116.099.105', 'C05.500.470.690.150', 'C07.320.450.670.130', 'C16.131.077.130', 'C16.320.700.175'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical risk factors associated with incidence and progression of periodontal conditions in pregnant women. | OBJECTIVES: Few large studies have investigated the progression of periodontal conditions during pregnancy in a comprehensive manner. This study aimed to identify clinical factors that were predictive of incidence/progression of periodontal measures in pregnant women adjusting for relevant predictors.MATERIAL AND METHO... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Demography', 'Disease Progression', 'Ethnic Groups', 'Female', 'Gingivitis', 'Humans', 'Incidence', 'Logistic Models', 'Middle Aged', 'Periodontal Index', 'Periodontitis', 'Pregnancy', 'Pregnancy Complications', 'Risk Factors', 'United States'] | 15,842,265 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['C23.550.291.656'], ['M01.686.754', 'N01.224.317'], ['C01.408', 'C07.465.714.258.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Endonasal Endoscopic Resection and Radiotherapy in Skull Base Chordomas. | OBJECTIVES: This study evaluates the impact combined endonasal endoscopic resection and radiotherapy for skull base chordomas.METHODS: Thirty-two patients with skull base chordomas between July 2006 and June 2015 were divided into 2 groups: the surgery alone group and the surgery with radiation therapy group.RESULTS: G... | ['Adult', 'Aged', 'Chordoma', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Natural Orifice Endoscopic Surgery', 'Radiotherapy, Adjuvant', 'Retrospective Studies', 'Skull Base Neoplasms', 'Survival Analysis', 'Treatment Outcome'] | 27,564,072 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.465.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.388.250.630', 'E04.502.250.630'], ['E02.186.775', 'E02.815.600'], ['E05.318.372.500.500.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Short term 13-cis-retinoic acid treatment at therapeutic doses elevates expression of leptin, GLUT4, PPARgamma and aP2 in rat adipose tissue. | Temporary defects in the plasma lipid and glucose homeostasis are frequent complication accompanying chronic treatment with 13-cis-retinoic acid (13cRA). White adipose tissue acts as an endocrine organ producing a variety of hormones (adipocytokines) including leptin, adiponectin, tumor-necrosis factor alpha (TNFalpha)... | ['Adipose Tissue, White', 'Animals', 'Dermatologic Agents', 'Fatty Acid-Binding Proteins', 'Gene Expression Regulation', 'Glucose Transporter Type 4', 'Isotretinoin', 'Leptin', 'Male', 'PPAR gamma', 'RNA, Messenger', 'Rats', 'Rats, Wistar', 'Receptor, Angiotensin, Type 1', 'Retinoid X Receptors', 'Reverse Transcriptase... | 19,212,007 | [['A10.165.114.830'], ['B01.050'], ['D27.505.954.444'], ['D12.776.157.170'], ['G05.308'], ['D12.776.157.530.500.500.937', 'D12.776.157.530.937.563.937', 'D12.776.543.585.500.500.937', 'D12.776.543.585.937.625.937'], ['D02.455.326.271.665.202.495.325', 'D02.455.426.392.368.367.379.249.700.325', 'D02.455.849.131.495.325'... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rechallenging breast cancer with tamoxifen therapy. | Advanced breast cancer which has temporarily responded to a course of tamoxifen (Nolvadex) therapy may show a response a second or third time when rechallenged by the same agent subsequently. The interval between such treatments may be critical for response. The observation also has important implications in the manage... | ['Aged', 'Breast Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Mastectomy', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Palliative Care', 'Skin Neoplasms', 'Tamoxifen'] | 6,198,122 | [['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E02.760.666', 'N02.421.585.666'], ['C04.588.805', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Possible Roles of New Mutations Shared by Asian and American Zika Viruses. | Originating in Africa, the Zika virus (ZIKV) has spread to Asia, Pacific Islands and now to the Americas and beyond. Since the first isolation in 1947, ZIKV strains have been sampled at various times in the last 69 years, but this history has not been reflected in studying the patterns of mutation accumulation in their... | ['Animals', 'Biological Evolution', 'Evolution, Molecular', 'Genome, Viral', 'Humans', 'Insect Vectors', 'Inverted Repeat Sequences', 'Mutation', 'Mutation Rate', 'Phylogeny', 'Phylogeography', 'RNA Stability', 'RNA, Viral', 'Structure-Activity Relationship', 'Zika Virus', 'Zika Virus Infection'] | 28,087,772 | [['B01.050'], ['G05.045', 'G16.075'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['G02.111.570.080.708.800.325', 'G05.360.080.708.800.325'], ['G05.365.590'], ['G05.045.250.750', 'G05.365.590.612', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Apolipoprotein E allele frequencies in patients with late-onset sporadic Alzheimer's dementia in Hungary. | INTRODUCTION: The presence of the apolipoprotein E4 allele (apoE4) has been recognized as a risk factor for the development of presenile and senile forms of Alzheimer's dementia (AD).MATERIAL AND METHODS: The apoE alleles frequency of 71 normal controls (NC), 60 demented controls (DC) and 50 senile type AD subjects was... | ['Age of Onset', 'Alleles', 'Alzheimer Disease', 'Apolipoproteins E', 'Base Sequence', 'Female', 'Genotype', 'Humans', 'Hungary', 'Incidence', 'Male', 'Polymerase Chain Reaction', 'Polymorphism, Genetic'] | 9,048,987 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['G05.360.340.024.340.030'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.40... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Comparison between buprenorphine and pentazocine given i.v. on demand in the control of postoperative pain. | A double-blind comparison between buprenorphine and pentazocine was performed in 20 patients using an on demand analgesic system to provide analgesia after operation. The quality of analgesia, assessed subjectively, was good with both drugs and drug consumptions were compatible with previous potency estimates. The mean... | ['Adolescent', 'Adult', 'Aged', 'Buprenorphine', 'Cholecystectomy', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Humans', 'Infusions, Parenteral', 'Male', 'Middle Aged', 'Morphinans', 'Pain, Postoperative', 'Pentazocine', 'Self Administration'] | 6,336,941 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['E04.210.120.172'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
European regulatory policies on medicines and public health needs. | The establishment of the EMEA has been a revolutionary step in the European pharmaceutical system. The 15 Member States of the European Union now share a common system for the evaluation of new medicinal products entering the European market. The decisions taken apply to the whole EU, with important implications for bo... | ['Drug Therapy', 'European Union', 'Guidelines as Topic', 'Humans', 'Legislation, Drug', 'Marketing of Health Services', 'Pharmaceutical Preparations', 'Public Policy', 'Quality Assurance, Health Care'] | 14,533,728 | [['E02.319'], ['I01.615.500.475'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.605', 'N03.706.615.402'], ['J01.219.687.550', 'N03.219.463.548', 'N05.300.430.500'], ['D26'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['N04.761.700', 'N05.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
The role of mechanical host-tumour interactions in the collapse of tumour blood vessels and tumour growth dynamics. | A mathematical model of residual stress evolution in a growing vascular tumour is presented, in an attempt to elucidate the poorly understood phenomenon of vascular collapse. Whereas earlier studies in this area have neglected the effects of mechanical interactions between the tumour and the surrounding host tissue, th... | ['Humans', 'Models, Biological', 'Neoplasms', 'Neovascularization, Pathologic', 'Stress, Mechanical'] | 16,384,586 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['C04'], ['C23.550.589.500'], ['G01.374.835']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NMR and MALDI-TOFMS analysis of a heteroglycan isolated from hot water extract of edible mushroom, Volvariella bombycina. | A water-soluble polysaccharide, isolated from the hot aqueous extract of an edible mushroom, Volvariella bombycina, consists of d-glucose, d-mannose, and d-galactose in a molar ratio 2:1:1. On the basis of total hydrolysis, methylation analysis, periodate oxidation, and NMR studies ((1)H, (13)C, TOCSY, DQF-COSY, NOESY,... | ['Agaricales', 'Carbohydrate Sequence', 'Hydrolysis', 'Magnetic Resonance Spectroscopy', 'Methylation', 'Models, Chemical', 'Molecular Sequence Data', 'Monosaccharides', 'Oxygen', 'Periodic Acid', 'Polysaccharides', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Temperature', 'Water'] | 18,495,096 | [['B01.300.179.100'], ['G02.111.570.160', 'L01.453.245.667.160'], ['G02.380'], ['E05.196.867.519'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['E05.599.495'], ['L01.453.245.667'], ['D09.947.875'], ['D01.268.185.550', 'D01.362.670'], ['D01.029.260.675', 'D01.475.705'], ['D09.698'], ['E05.196.566.755'], ['G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Inhaled drugs as risk factors for community-acquired pneumonia. | The effect of inhaled drugs in community-acquired pneumonia (CAP) is unclear. This case-control study was designed to determine whether inhaled drugs were risk factors for CAP. All incident cases of confirmed CAP that occurred over 1 yr in patients with chronic bronchitis (CB), chronic obstructive pulmonary disease (CO... | ['Administration, Inhalation', 'Adult', 'Aged', 'Aged, 80 and over', 'Asthma', 'Bronchodilator Agents', 'Case-Control Studies', 'Cholinergic Antagonists', 'Community-Acquired Infections', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Nebulizers and Vaporizers', 'Pulmonary Disease, Chronic Obstructive', 'Risk... | 20,525,710 | [['E02.319.267.050'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D27.505.519.625.120.200'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Maintenance of Crohn's disease over 12 months: fixed versus flexible dosing regimen using budesonide controlled ileal release capsules. | BACKGROUND: It may be possible to achieve more effective management of Crohn's Disease by introducing a flexible dosage regimen sensitive to patients' needs.AIM: Comparison of the efficacy and tolerability of a fixed vs. flexible budesonide controlled ileal release treatment regimen for the prevention and management of... | ['Adult', 'Aged', 'Algorithms', 'Anti-Inflammatory Agents', 'Budesonide', 'Crohn Disease', 'Delayed-Action Preparations', 'Double-Blind Method', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Middle Aged', 'Severity of Illness Index', 'Treatment Outcome'] | 11,552,903 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['D27.505.954.158'], ['D04.210.500.745.745.654.105'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['D26.255.210', 'E02.319.300.253'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['B01.050.15... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Thirty-day readmission and reoperation after surgery for spinal tumors: a National Surgical Quality Improvement Program analysis. | OBJECTIVE The goal of this study was to use a large national registry to evaluate the 30-day cumulative incidence and predictors of adverse events, readmissions, and reoperations after surgery for primary and secondary spinal tumors. METHODS Data from adult patients who underwent surgery for spinal tumors (2011-2014) w... | ['Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Readmission', 'Postoperative Complications', 'Prospective Studies', 'Quality Improvement', 'Registries', 'Reoperation', 'Spinal Neoplasms', 'Spine', 'Time Factors', 'United States'] | 27,476,847 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.400.620', 'N02.421.585.400.620'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['J01.293.754', 'N04.761.744'], ['E05.318.308.970', 'N04.45... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Pre-intervention cerebral blood volume predicts outcomes in patients undergoing endovascular therapy for acute ischemic stroke. | BACKGROUND: Pre-intervention perfusion imaging is increasingly becoming part of stroke triage. Small studies supporting imaging based patient selection have been published. The goal of this larger study was to determine if perfusion imaging could impact on functional outcomes in patients undergoing stroke interventions... | ['Aged', 'Aged, 80 and over', 'Blood Volume', 'Brain Ischemia', 'Cerebrovascular Circulation', 'Databases, Factual', 'Endovascular Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Preoperative Care', 'Prospective Studies', 'Retrospective Studies', 'Stroke', 'Treatment Outcome'] | 22,434,904 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G09.188.130', 'G09.330.380.092'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G09.330.100.159'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Adrenomedullin, a vasodilator peptide implicated in hemodynamic alterations of liver cirrhosis: relationship to nitric oxide. | This prospective cohort study was aimed at investigating the role of adrenomedullin, a potent vasodilator peptide, in liver cirrhosis and its relationship with nitric oxide and cytokines. Overall, 66 consecutive patients with liver cirrhosis and 15 controls matched for age and sex distribution were included. Adrenomedu... | ['Adrenomedullin', 'Aged', 'Ascites', 'Cohort Studies', 'Female', 'Hemodynamics', 'Humans', 'Interleukin-6', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Nitric Oxide', 'Peptides', 'Prospective Studies', 'Tumor Necrosis Factor-alpha', 'Vasodilator Agents'] | 10,063,925 | [['D06.472.699.077', 'D12.644.548.017'], ['M01.060.116.100'], ['C23.550.081'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['C06.552.630', '... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Brazing joints of gold alloy used in porcelain-fused-to-metal restorations and their resistance to deflection fatigue. | The aim of this study was to compare the resistance to deflection fatigue of a gold alloy used in porcelain-fused-to-metal restorations with and without a brazing joint. Pre-ceramic brazing filler metal was used to join the parent specimens of gold alloy together. The deflection fatigue test was carried out mainly with... | ['Analysis of Variance', 'Bite Force', 'Dental Restoration Failure', 'Dental Soldering', 'Dental Stress Analysis', 'Denture, Partial, Fixed', 'Equipment Failure Analysis', 'Gold Alloys', 'Materials Testing', 'Metal Ceramic Alloys', 'Microscopy, Electron, Scanning', 'Tensile Strength'] | 9,219,989 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E06.276.125'], ['E06.323.400', 'E06.780.346.725'], ['E06.912.190'], ['E06.308'], ['E06.780.346.760.943.271', 'E07.695.190.200.220.220'], ['E05.325.192'], ['D01.379.375', 'D01.552.033.533', 'D25.058.451', 'D25.339.208.534', 'J01.637.051.058.451', 'J01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Endoscopic release of the ulnar nerve at the elbow using the Agee device: a cadaveric study. | PURPOSE: The purpose of this study was to assess the safety and efficacy of the Agee endoscopic system (3M, Orthopedic Products, St. Paul, MN) for ulnar nerve decompression at the elbow.TYPE OF STUDY: A cadaveric study.METHODS: The ulnar nerve was identified through a 3-cm longitudinal incision between the medial epico... | ['Cadaver', 'Decompression, Surgical', 'Elbow Joint', 'Endoscopy', 'Humans', 'Ulnar Nerve', 'Ulnar Nerve Compression Syndromes'] | 15,944,624 | [['C23.550.260.224'], ['E04.188'], ['A02.835.583.290'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.050.850'], ['C10.668.829.500.850.600', 'C10.668.829.550.925', 'C26.844.150.957']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pityriasis rubra pilaris with acantholysis. | Two patients developed a papulosquamous eruption in a widespread distribution which progressed with islands of sparing of uninvolved skin characteristic clinically of adult-onset pityriasis rubra pilaris (PRP). Biopsies from both patients showed multiple areas of nonfollicular and follicular suprabasilar and intra-epid... | ['Acantholysis', 'Aged', 'Humans', 'Male', 'Middle Aged', 'Pityriasis Rubra Pilaris'] | 8,793,664 | [['C17.800.865.070', 'C23.550.035'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C17.800.859.600.685']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of a novel mutation in the EYA1 gene in a Korean family with branchio-oto-renal (BOR) syndrome. | The branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by the association of branchial cysts or fistulae, external ear malformation and/or preauricular pits, hearing loss, and renal anomalies. Mutations in the EYA1 gene on the chromosome band 8q13.3, the human homologue of the Drosophila ... | ['Base Sequence', 'Branchio-Oto-Renal Syndrome', 'Child, Preschool', 'Chromosomes, Human, Pair 8', 'DNA', 'Ear', 'Female', 'Hearing Aids', 'Hearing Loss', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Kidney', 'Korea', 'Mutation', 'Nuclear Proteins', 'Pedigree', 'Phenotype', 'Protein Tyrosine Phosphatases... | 16,005,355 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C16.131.077.208', 'C16.131.260.090', 'C16.320.180.090'], ['M01.060.406.448'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['D13.444.308'], ['A01.456.313', 'A09.246'], ['E07.305.906.500', 'E07.814.458'], ['C09.218.458.341', 'C10.597.751.41... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
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