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Embryonic stem cells improve skeletal muscle recovery after extreme atrophy in mice. | INTRODUCTION: We injected embryonic stem cells into mouse tibialis anterior muscles subjected to botulinum toxin injections as a model for reversible neurogenic atrophy.METHODS: Muscles were exposed to botulinum toxin for 4 weeks and allowed to recover for up to 6 weeks. At the onset of recovery, a single muscle inject... | ['Animals', 'Botulinum Toxins', 'Embryonic Stem Cells', 'Humans', 'Male', 'Mice', 'Muscle, Skeletal', 'Muscular Atrophy', 'Recovery of Function', 'Stem Cell Transplantation'] | 24,934,406 | [['B01.050'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['A11.872.700.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['A02.633.567', 'A10.690.552.500'], ['C10.597.613.612', 'C23.300.070.500', 'C23.888.592.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Experimental study on adenosine triphosphate combining bone marrow mesenchymal stem cells transplantation in treatment of spinal cord injury in rats]. | OBJECTIVE: Adenosine triphosphate (ATP) can promote the repair of spinal cord injury (SCI). To investigate the effect of ATP combined with bone marrow mesenchymal stem cells (BMSCs) transplantation on SCI, and to evaluate the synergistic action of ATP and BMSCs in the repair of SCI and the feasibility of the combined t... | ['Adenosine Triphosphate', 'Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Disease Models, Animal', 'Female', 'Male', 'Mesenchymal Stem Cell Transplantation', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord Injuries'] | 21,046,813 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.095.147.500.500.625', 'E04.936.225.687.625'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphological transformation and DNA adduct formation by dibenz[a,h]anthracene and its metabolites in C3H10T1/2CL8 cells. | The major routes of metabolic activation of dibenz[a,h]-anthracene (DBA) have been studied in transformable C3H10T1/2CL8 (C3H10T1/2) mouse embryo fibroblasts in culture. The morphological transforming activities of three potential intermediates formed by metabolism of DBA by C3H10T1/2 cells, trans-3,4-dihydroxy-3,4-dih... | ['Animals', 'Benz(a)Anthracenes', 'Biotransformation', 'Cell Transformation, Neoplastic', 'DNA Adducts', 'Fibroblasts', 'Isotope Labeling', 'Mice', 'Mice, Inbred C3H', 'Oxidation-Reduction', 'Phosphorus Radioisotopes', 'Structure-Activity Relationship'] | 7,955,058 | [['B01.050'], ['D02.455.426.559.847.149', 'D04.615.149'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D13.444.308.135', 'G05.200.104'], ['A11.329.228'], ['E05.522'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene expression profiles in a porcine model of infarction: differential expression after intracoronary injection of heterologous bone marrow mesenchymal cells. | Myocardial infarction is one of the main causes of mortality in developed countries. Injection of bone marrow mesenchymal stem cells (BMMSC) with the ability to regenerate lost cardiomyocytes is a promising therapy for heart failure. To evaluate this strategy, an in vivo porcine model of infarction was used. Gene expre... | ['Animals', 'Collagen Type I', 'Disease Models, Animal', 'Gene Expression Profiling', 'Mesenchymal Stem Cell Transplantation', 'Myocardial Infarction', 'Swine'] | 19,715,896 | [['B01.050'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.393.332'], ['E02.095.147.500.500.625', 'E04.936.225.687.625'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stigma never dies: Mourning a spouse who died of AIDS in China. | Stigma towards people with HIV (PHIV) can affect their family members. In this study of 68 HIV seronegative participants in China whose spouse died of AIDS, 35.3% reported prolonged grief. Stigma beliefs towards PHIV (i.e., belief that PHIV's death leaves the deceased, the family and society better off) predicted grief... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Bereavement', 'China', 'Cross-Sectional Studies', 'Death', 'Female', 'Humans', 'Male', 'Middle Aged', 'Social Stigma', 'Spouses', 'Suicide'] | 26,553,145 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['F01.470.142'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C23.550.260'], [... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Design of switchable wettability sensor for paraquat based on clicking calix[4]arene. | A calix[4]arene acetylene (C4AE)-modified gold surface is successfully constructed in situ via click chemistry. The functionalized surface is used for selective recognition of paraquat by a wettability switch. Impedance measurements showed that the surface also expresses recognition for paraquat with a high sensitivity... | ['Acetylene', 'Calixarenes', 'Click Chemistry', 'Electric Impedance', 'Electrochemical Techniques', 'Gold', 'Herbicides', 'Paraquat', 'Phenols', 'Sensitivity and Specificity', 'Surface Properties', 'Wettability'] | 22,407,032 | [['D02.455.326.397.259'], ['D04.345.025'], ['E05.197.124', 'J01.897.836.249.124'], ['G01.358.500.249.277.350'], ['E05.301'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D27.720.031.700.366', 'D27.888.723.366'], ['D03.383.725.762.621'], ['D02.455.426.559.389.657'], ['E05.318.370.800', 'E05.318.740.872',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Incidence, pathology and prevention of keel bone deformities in the laying hen. | 1. As a baseline study of the nature and incidence of keel deformities in laying hens, keel condition was examined in three different strains of hen from a total of 4 different caged environments (two commercial farms and two experimental farms). Incidence of keel deformity on farms in end of lay hens ranged from 2.6 t... | ['Animals', 'Biomechanical Phenomena', 'Bone Density', 'Bone and Bones', 'Chickens', 'Female', 'Fractures, Bone', 'Male', 'Minerals', 'Osteoporosis', 'Oviposition', 'Poultry Diseases', 'Selection, Genetic'] | 15,327,118 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['C26.404'], ['D01.578'], ['C05.116.198.579', 'C18.452.104.579'], ['G08.686.784.480'], ['C22.131.728'], ['G05.783']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anaerobic metabolism induces greater total energy expenditure during exercise with blood flow restriction. | PURPOSE: We investigated the energy system contributions and total energy expenditure during low intensity endurance exercise associated with blood flow restriction (LIE-BFR) and without blood flow restriction (LIE).METHODS: Twelve males participated in a contra-balanced, cross-over design in which subjects completed a... | ['Adolescent', 'Adult', 'Anaerobiosis', 'Blood Circulation', 'Exercise', 'Female', 'Humans', 'Lactic Acid', 'Male', 'Oxygen Consumption', 'Young Adult'] | 29,596,452 | [['M01.060.057'], ['M01.060.116'], ['G02.111.062', 'G03.078'], ['G09.330.100'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['G03.680'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Foreign physicians practicing in France (problems posed by the application of the law of July 13, 1972)]. | The 13 July 1972 law defined a procedure which applies to physicians wishing to practise in France but who don't meet the double requirement: having the French nationality (or being a citizen of a member state of the European Union) and holding the national diploma of Doctor of Medicine (or a diploma of the European Co... | ['Foreign Medical Graduates', 'France', 'Humans'] | 7,895,113 | [['M01.526.407.435', 'M01.526.485.810.390', 'N02.360.810.390'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The effect of age on the pharmacokinetics and pharmacodynamics of midazolam. | OBJECTIVE: We investigated the pharmacologic properties of midazolam with special regard to age using the electroencephalogram (EEG) as a measure of the hypnotic-sedative effect.METHODS: Nine younger (24 to 28 years) and nine elderly (67 to 81 years) male volunteers received midazolam by a computer-controlled device. T... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Blood Pressure', 'Dose-Response Relationship, Drug', 'Electroencephalography', 'Female', 'Heart Rate', 'Humans', 'Hypnotics and Sedatives', 'Infusions, Intravenous', 'Male', 'Midazolam', 'Respiration', 'Volunteers'] | 10,391,668 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immune responses in normal Indian langur monkeys (Presbytis entellus)--a primate model for visceral leishmaniasis. | The Indian langur monkey (Presbytis entellus) is an experimental host for a range of human diseases and for the assessment of vaccine candidate antigens to some common parasitic infections. This experimental host is particularly suitable for the follow-up of immunological responses. To understand some of the mechanism ... | ['Animals', 'Antibodies, Helminth', 'Antibodies, Monoclonal', 'Antibodies, Protozoan', 'Cercopithecidae', 'Cytokines', 'Disease Models, Animal', 'Enzyme-Linked Immunosorbent Assay', 'Immunity, Cellular', 'India', 'Leishmaniasis, Visceral', 'Leukocytes, Mononuclear', 'Male', 'Mitogens'] | 15,061,718 | [['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['B01.050.150.900.649... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Khellin, a naturally occurring furochromone, used for the photochemotherapy of skin diseases: mechanism of action. | Khellin, a naturally occurring furochromone, used in the past as a coronary vasodilator, has recently been used in the photochemotherapeutic treatment of vitiligo and psoriasis. With the aim of elucidating its mechanism of action, the interactions both in ground and excited states between the drug and DNA were studied ... | ['Animals', 'Carcinoma, Ehrlich Tumor', 'Chemical Phenomena', 'Chemistry', 'Cross-Linking Reagents', 'DNA', 'Dialysis', 'Khellin', 'Methoxsalen', 'Photochemistry', 'Skin Diseases', 'Solubility', 'Spectrophotometry, Ultraviolet'] | 3,203,737 | [['B01.050'], ['C04.557.470.200.200', 'C04.619.169'], ['G02'], ['H01.181'], ['D27.720.470.410.210'], ['D13.444.308'], ['E05.196.353', 'G02.186'], ['D03.383.663.283.446.794.300', 'D03.633.100.150.446.794.300', 'D03.633.300.770.300'], ['D03.383.663.283.446.794.500', 'D03.633.100.150.446.794.500', 'D03.633.300.770.500'], ... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of microsporidiosis due to Enterocytozoon bieneusi and Encephalitozoon (Septata) intestinalis among patients with AIDS-related diarrhea: determination by polymerase chain reaction to the microsporidian small-subunit rRNA gene. | Microsporidia are emerging as opportunistic pathogens in patients with AIDS. Enterocytozoon bieneusi and Encephalitozoon (Septata) intestinalis have been implicated in enteric infections in AIDS patients with chronic diarrhea, a wasting syndrome, and malabsorption. We used the polymerase chain reaction (PCR) and primer... | ['AIDS-Related Opportunistic Infections', 'Animals', 'Diarrhea', 'Encephalitozoon', 'Encephalitozoonosis', 'Humans', 'Microsporida', 'Microsporidiosis', 'Polymerase Chain Reaction', 'Prevalence', 'RNA, Protozoan', 'RNA, Ribosomal'] | 8,922,793 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['B01.050'], ['C23.888.821.214'], ['B01.300.360.500.500.100.175'], ['C01.150.703.617.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.300.360.500.500'], ['C01.150.703.617'], ['E0... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stages of delay in oral cancer care evaluated at a tertiary health centre. | BACKGROUND: To examine the stages of delay in presentation and management of oral cancer patients at University College Hospital Ibadan and compare findings with previous studies.METHODS: A 20-year retrospective analysis of the delay stages among oral cancer patients that utilized patient's biodata and clinical data.RE... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Child', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Nigeria', 'Retrospective Studies', 'Tertiary Care Centers', 'Time Factors', 'Time-to-Treatment', 'Young Adult'] | 24,839,739 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['C04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Increasing breast milk production for premature infants with a relaxation/imagery audiotape. | Many women whose premature infants are hospitalized in a newborn intensive care unit choose to express breast milk for their babies. Yet anxiety, fatigue, and emotional stress are powerful inhibitors of lactation. To facilitate the breast-feeding experience, intervention mothers were given a 20-minute audio cassette ta... | ['Female', 'Humans', 'Imagination', 'Infant, Newborn', 'Infant, Premature', 'Lactation', 'Milk, Human', 'Pregnancy', 'Relaxation Therapy', 'Tape Recording'] | 2,642,620 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.188.634'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['G08.686.523', 'G08.686.702.500'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07.203.300.350.525.500', 'J02.200.700.500', 'J02.500.350.525.500'], ['G08.686.784.769'], ['E02.190.525.875', 'F... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Persulfonylation of amines applied to the synthesis of higher generation dendrimers. | Systematic analysis of the persulfonylation of branched aromatic oligoamines with different arylsulfonyl chlorides allowed optimization of the repetitive steps involved in the synthesis of the sulfonimide-based dendrimers. The optimized procedures afforded the fourth generation N- and pentaphenylene-centered dendrimers... | ['Amines', 'Dendrimers', 'Molecular Structure', 'Sulfur Compounds'] | 18,358,000 | [['D02.092'], ['D05.750.327', 'E02.319.300.380.200', 'J01.637.512.600.200'], ['G02.111.570', 'G02.466'], ['D01.875', 'D02.886']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Normotension, ventricular tachycardia and palpitation: an unusual presentation of phaeochromocytoma. | Phaeochromocytomas are rare catecholamine-producing tumours arising from the cells of the sympathetic nervous system. They account for less than one per cent of hypertension. Undiagnosed sufferers are usually hypertensive and experience episodes of hypertensive crisis. Patients presenting with hypertensive attacks only... | ['Adrenal Gland Neoplasms', 'Adult', 'Arrhythmias, Cardiac', 'Blood Pressure', 'Humans', 'Male', 'Pheochromocytoma', 'Tachycardia'] | 2,590,629 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['C14.280.067', 'C23.550.073'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.700.725', 'C04.557.580.625.650.700.725'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ethics of esthetic dentistry. | Patient demand for esthetics has increased globally, and often for reasons of patient self-esteem. However, important ethical issues encompass treatment for purely esthetic reasons. Also, perceptions of what is esthetic differ among patients and clinicians. Therefore, the aim of this article is to make suggestions rega... | ['Adult', 'Esthetics, Dental', 'Ethics, Dental', 'Female', 'Humans', 'Informed Consent', 'Insurance, Dental', 'Retreatment', 'Self Concept', 'Terminology as Topic'] | 15,202,591 | [['M01.060.116'], ['E06.420'], ['K01.752.566.479.171.132.500', 'K01.752.622.416', 'N05.350.340.162.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['N03.219.521.576.343.450'], ['E02.887'], ['F01.752.747.792'], ['L01.55... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Are physiotherapists comfortable with person-centred practice? An autoethnographic insight. | PURPOSE: This study aimed to understand our shared conflicting response and discomfort to person-centred rehabilitation within the context of our physiotherapy rehabilitation culture by reflecting on our own experiences as research physiotherapists and clinicians.METHOD: This study used autoethnographical methods to ex... | ['Attitude of Health Personnel', 'Data Collection', 'Goals', 'Humans', 'Organizational Culture', 'Patient-Centered Care', 'Physical Therapists'] | 23,713,969 | [['F01.100.050', 'N05.300.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.658.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.606'], ['N04.590.233.727.407'], ['M01.526.485.790', 'N02.360.790']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Dermatoglyphics in Cuban mongols. | Finger and palm prints of 220 Cuban mongols, all trisomic 21, were statistically compared with those of a group of 400 normal Cuban individuals. The most important dermatoglyphic findings in the patients were: an excess of ulnar loops on the 2nd and 3rd fingers, and radial loops on the 4th and 5th fingers; a paucity of... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Cuba', 'Dermatoglyphics', 'Down Syndrome', 'Female', 'Humans', 'Infant', 'Male', 'Sex Factors'] | 6,451,140 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Remissions in hairy-cell leukemia with pentostatin (2'-deoxycoformycin). | The Eastern Cooperative Oncology Group conducted a study of pentostatin (2'-deoxycoformycin) in 37 patients with hairy-cell leukemia. Among the 27 patients who met all the study's entry criteria, the response rate was 96 percent, with 16 patients (59 percent) entering complete remission and 10 patients (37 percent) par... | ['Antineoplastic Agents', 'Coformycin', 'Drug Evaluation', 'Female', 'Humans', 'Interferons', 'Leukemia, Hairy Cell', 'Male', 'Pentostatin', 'Remission Induction', 'Ribonucleosides', 'Splenectomy'] | 2,434,850 | [['D27.505.954.248'], ['D03.383.742.680.350.200', 'D13.570.685.350.200', 'D13.570.800.410.200'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['C04.557.337.415', 'C15.604.515.553', 'C20.683.515.517'], ['D03.383.742.68... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trade-offs among catch, bycatch, and landed value in the American Samoa longline fishery. | The interspecific preferences of fishes for different depths and habitats suggest fishers could avoid unwanted catches of some species while still effectively targeting other species. In pelagic longline fisheries, albacore (Thunnus alalunga) are often caught in relatively cooler, deeper water (>100 m) than many specie... | ['American Samoa', 'Animals', 'Conservation of Natural Resources', 'Endangered Species', 'Fisheries', 'Fishes', 'Species Specificity', 'Tuna'] | 24,628,499 | [['Z01.639.760.815.800.100'], ['B01.050'], ['J01.256', 'N06.230.080'], ['B01.050.050.565', 'G16.500.275.157.049.250', 'N06.230.080.200', 'N06.230.124.049.250'], ['J01.040.168.300', 'J03.540.280'], ['B01.050.150.900.493'], ['G16.824'], ['B01.050.150.900.493.602.825']] | ['Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
N-acetylcysteine ameliorates carbofuran-induced alterations in lipid composition and activity of membrane bound enzymes. | The present work investigates the protective effects of N-acetylcysteine (NAC) on carbofuran-induced alterations in lipid composition and activity of membrane bound enzymes (Na+-K+-ATPase and Ca2+-ATPase) in the rat brain. Animals were exposed to carbofuran at a dose of 1 mg/kg body weight, orally, for a period of 28 d... | ['Acetylcysteine', 'Animals', 'Body Weight', 'Calcium-Transporting ATPases', 'Carbofuran', 'Cerebral Cortex', 'Cholesterol', 'Free Radical Scavengers', 'Insecticides', 'Lipid Metabolism', 'Lipid Peroxidation', 'Male', 'Phospholipids', 'Rats', 'Rats, Wistar', 'Sodium-Potassium-Exchanging ATPase'] | 16,496,214 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms. | Neurexins are cell adhesion molecules that help to specify and stabilize synapses and provide receptors for neuroligins, neurexophilins, dystroglycans and alpha-latrotoxins. We previously reported significant allele frequency differences for single nucleotide polymorphisms (SNPs) in the neurexin 3 (NRXN3) gene in each ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Alcoholism', 'Alleles', 'Alternative Splicing', 'Base Sequence', 'Case-Control Studies', 'Cell Adhesion Molecules, Neuronal', 'Cerebral Cortex', 'DNA Primers', 'Exons', 'Female', 'Gene Expression', 'Genotype', 'Haplotypes', 'Humans', 'Introns', 'Male', 'Middle Aged', 'Nerve Tissu... | 17,804,423 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C25.775.100.250', 'F03.900.100.350'], ['G05.360.340.024.340.030'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.5... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Vagus nerve stimulation blocks vascular permeability following burn in both local and distal sites. | Recent studies have shown that vagus nerve stimulation (VNS) can block the burn-induced systemic inflammatory response (SIRS). In this study we examined the potential for VNS to modulate vascular permeability (VP) in local sites (i.e. skin) and in secondary sites (i.e. lung) following burn. In a 30% total body surface ... | ['Animals', 'Burns', 'Capillary Permeability', 'Dextrans', 'Disease Models, Animal', 'Fluorescent Dyes', 'Lung', 'Mice', 'Mice, Inbred BALB C', 'Skin', 'Vagus Nerve Stimulation'] | 22,694,873 | [['B01.050'], ['C26.200'], ['G03.143.330', 'G09.330.165'], ['D05.750.078.562.272', 'D09.698.365.272'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of tetraazamacrocyclic ligands on the nitric oxide reactivity of their cobalt(II) complexes. | The reactions of cobalt(II) complexes of tetraazamacrocyclic tropocoronand (TC) ligands with nitric oxide (NO) were investigated. When [Co(TC-5,5)] was allowed to react with NO(g), the {CoNO}(8) mononitrosyl [Co(NO)(TC-5,5)] was isolated and structurally characterized. In contrast, a {Co(NO)(2)}(10) species formed when... | ['Aza Compounds', 'Cobalt', 'Coordination Complexes', 'Ligands', 'Macrocyclic Compounds', 'Models, Molecular', 'Nitric Oxide', 'Spectrophotometry, Infrared'] | 22,742,582 | [['D02.145'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['D01.234', 'D02.257'], ['D27.720.470.480'], ['D04.345'], ['E05.599.595'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['E05.196.712.726.676', 'E05.196.867.826.676']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Toward an understanding of anticipatory pleasure deficits in schizophrenia: Memory, prospection, and emotion experience. | Anticipatory pleasure deficits have been observed in people with schizophrenia. Less is known about the extent to which interrelated processes that comprise anticipatory pleasure, including memory, prospection, and emotion experience are disrupted. We asked people with (n = 32) and without (n = 29) schizophrenia or sch... | ['Adult', 'Anhedonia', 'Female', 'Humans', 'Male', 'Memory', 'Memory, Episodic', 'Middle Aged', 'Neuropsychological Tests', 'Pleasure', 'Schizophrenic Psychology'] | 26,950,753 | [['M01.060.116'], ['C10.597.606.057', 'C23.888.592.604.039', 'F01.700.039'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.254'], ['M01.060.116.630'], ['F04.711.513'], ['F01.470.867', 'F02.830.816.492'], ['F04.824']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A direct binding assay for the vascular cell adhesion molecule-1 (VCAM1) interaction with alpha 4 integrins. | Vascular cell adhesion molecule-1 (VCAM1) is a member of the immunoglobulin (Ig) superfamily which interacts with the alpha 4 integrins alpha 4 beta 1 (very late antigen 4: VLA4) and alpha 4 beta 7, which are constitutively expressed on many leukocyte subsets and play a key role in cell trafficking and activation. Usin... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, CD', 'Binding, Competitive', 'Cell Adhesion', 'Fluorescent Antibody Technique', 'Humans', 'Integrin alpha4', 'Integrins', 'Leukemia', 'Magnesium', 'Mice', 'Protein Binding', 'Rats', 'Tumor Cells, Cultured', 'Vascular Cell Adhesion Molecule-1'] | 8,640,376 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.035', 'D23.101.100.110'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G04.022'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the lateral flow immunoassays (LFIA) for the diagnosis of Helicobacter pylori infection. | Helicobacter pylori infection is the most common human infection where approximately 50% of the world populations are infected. The diagnosis of such infection is mainly done by endoscopy where gastric biopsies are examined for the presence of H. pylori. Such invasive approach is costly, time consuming and generally re... | ['Antibodies', 'Feces', 'Gastrointestinal Diseases', 'Gastroscopy', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Immunoassay', 'Sensitivity and Specificity', 'Urea'] | 23,994,110 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A12.459'], ['C06.405'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A study of the mechanisms of cytotoxicity of Ara-C on three human leukemic cell lines. | The main biochemical determinants involved in cytosine arabinoside (Ara-C) metabolism were studied in one lymphoblastic (Reh) and two myeloid (HL60 and K562) human leukemic cell lines exhibiting various sensitivities to Ara-C, Reh being the most and HL60 the least sensitive. The level of intracellular Ara-C accumulatio... | ['Arabinofuranosylcytosine Triphosphate', 'Cytarabine', 'DNA', 'DNA Ligases', 'DNA Polymerase II', 'DNA, Neoplasm', 'Deoxycytidine Kinase', 'Deoxycytosine Nucleotides', 'Humans', 'Leukemia', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Leukemia, Promyelocytic, Acute', 'Precursor Cell Lymphoblastic Leukemia-Lymp... | 2,752,506 | [['D03.383.742.686.246.050', 'D13.695.065.200', 'D13.695.740.246.050'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['D13.444.308'], ['D08.811.074.500', 'D08.811.464.754.600'], ['D08.811.913.696.445.308.300.230'], ['D13.444.308.425'], ['D08.811.913.696.620.175'], ['D03.383.742.686.246.425', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ferT encodes a meiosis-specific nuclear tyrosine kinase. | ferT is a mouse testis-specific mRNA, shown previously to potentially encode a 51 kilodalton tyrosine kinase termed p51ferT. The accumulation of ferT RNA is restricted to primary spermatocytes that are at the prophase stage of the first spermatogenic meiotic division. By using antibodies raised against a synthetic pept... | ['Animals', 'CHO Cells', 'Cricetinae', 'Male', 'Meiosis', 'Mice', 'Nuclear Matrix', 'Nuclear Proteins', 'Organ Specificity', 'Peptide Fragments', 'Prophase', 'Protein-Tyrosine Kinases', 'Recombinant Fusion Proteins', 'Spermatocytes', 'Transfection'] | 8,373,729 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['G04.144.220.220.687', 'G05.113.220.687'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.430.106.279.345.700'], ['D12.776.660'], ['G07.650'], ['D12.644.541'], ['G04.144.220.220.687.883', 'G04.144.220.220.781.906', '... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduction in parenteral nutrition related complications in the newborn. | A comparison of total parenteral nutrition (TPN) related complication in newborns was made between two study periods, namely, 1986 (Study A) and 1989-90 (Study B). A significant reduction was seen in all complications in Study B. Local complications (thrombophlebitis, gangrene, abscess) reduced from 80.0 to 29.4%, sept... | ['Humans', 'India', 'Infant Nutritional Physiological Phenomena', 'Infant, Newborn', 'Infusions, Intravenous', 'Intensive Care Units, Neonatal', 'Intensive Care, Neonatal', 'Parenteral Nutrition', 'Skin', 'Skin Diseases, Infectious', 'Thrombophlebitis', 'Water-Electrolyte Imbalance'] | 1,752,674 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['G07.203.650.220.500'], ['M01.060.703.520'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['N02.278.388.493.390.380'], ['E02.760.190.405', 'N02.421.585.190.500'], ['E02.421.505', 'E02.642.500.505'], ['A17.815'], ['C01.800', 'C17.800.838'], ['C14... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Conjoined lumbosacral nerve roots. Management of herniated discs and lateral recess stenosis in patients with this anomaly. | Anomalous L-5 and S-1 nerve roots occur infrequently. If not properly recognized, surgery for entrapment disorders may result in serious neural injury because of an improper surgical approach in exposure and in removing the underlying herniated discs. The diagnosis has been made preoperatively since the introduction of... | ['Adult', 'Female', 'Humans', 'Intervertebral Disc Displacement', 'Laminectomy', 'Lumbosacral Region', 'Male', 'Metrizamide', 'Middle Aged', 'Myelography', 'Nerve Compression Syndromes', 'Spinal Nerve Roots'] | 7,277,006 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['A01.923.176.519'], ['D02.241.223.100.400.880.520', 'D02.455.426.559.389.127.375.880.520', 'D09.408.051.545'], ['M01.060.116.630'], ['E01.370.350.578.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Plasma brain natriuretic peptide is a biochemical marker for the prediction of progressive ventricular remodeling after acute myocardial infarction. | To investigate the relation between plasma brain natriuretic peptide (BNP) and progressive ventricular remodeling, we measured plasma BNP and atrial natriuretic peptide (ANP) in 30 patients with acute myocardial infarction on days 2, 7, 14, and 30 after the onset. Left ventricular end-diastolic volume index (EDVI), end... | ['Adult', 'Aged', 'Aged, 80 and over', 'Atrial Natriuretic Factor', 'Biomarkers', 'Female', 'Hemodynamics', 'Humans', 'Hypertrophy, Left Ventricular', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Natriuretic Peptide, Brain', 'Nerve Tissue Proteins', 'Predictive Value of Tests', 'Ventricular Function, Left'] | 9,453,517 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['D23.101'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.195.400', 'C23.300.775.250.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The clinical significance of hemoglobinopathies in the Hamilton region: a twenty-year review. | Between 1970-1990, the Laboratory tested 38,391 specimens for hemoglobinopathies, of which 7,935 were positive. The major abnormalities detected were beta thalassemia trait (4,688), alpha thalassemia trait (1,248) and sickle cell trait (847). Clinically significant hemoglobinopathies detected were Hemoglobin H disease ... | ['Hemoglobin C Disease', 'Hemoglobin E', 'Hemoglobin SC Disease', 'Hemoglobinopathies', 'Hemoglobins, Abnormal', 'Humans', 'Ontario', 'Sickle Cell Trait', 'alpha-Thalassemia', 'beta-Thalassemia'] | 1,458,712 | [['C15.378.071.141.150.490', 'C15.378.420.463', 'C16.320.070.490', 'C16.320.365.463'], ['D12.776.124.400.463.375', 'D12.776.422.316.762.426.375'], ['C15.378.071.141.150.150.440', 'C15.378.420.155.440', 'C16.320.070.150.440', 'C16.320.365.155.440'], ['C15.378.420', 'C16.320.365'], ['D12.776.124.400.463', 'D12.776.422.31... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Evidence for theory of mind deficits in euthymic patients with bipolar disorder. | OBJECTIVE: i) To investigate the subtle ToM (theory of mind) deficits in euthymic patients with bipolar disorder. ii) To investigate the impact of non-ToM cognitive deficits on ToM abilities.METHOD: Forty-three euthymic patients with bipolar disorder and 30 healthy control subjects were involved in this study. ToM was ... | ['Adult', 'Analysis of Variance', 'Attention', 'Bipolar Disorder', 'Cognition Disorders', 'Emotions', 'Face', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Pattern Recognition, Visual', 'Reference Values', 'Social Perception'] | 15,992,392 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.104.214'], ['F03.084.500'], ['F03.615.250'], ['F01.470'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.978.810'], ['F02.463.593.752']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Kansas LIFE project-living initiatives for end-of-life care. | BACKGROUND: Numerous studies continue to demonstrate the needs for improved palliative and end-of-life care.OBJECTIVE: Kansas stakeholders joined together, under the leadership of the Kansas Hospice and Palliative Care Organization (formerly the Association of Kansas Hospices) in 1997, to improve palliative and end-of-... | ['Communication', 'Community Health Planning', 'Cooperative Behavior', 'Health Care Coalitions', 'Humans', 'Kansas', 'Palliative Care', 'Program Evaluation', 'Quality Assurance, Health Care', 'Terminal Care'] | 15,684,852 | [['F01.145.209', 'L01.143'], ['N03.349.650.185'], ['F01.145.813.115'], ['N03.540.452.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.510.390'], ['E02.760.666', 'N02.421.585.666'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N04.761.700', 'N05.700'], ['E02.760.905', 'N02.421.585.905']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Effect of premolar and molar occlusal angle on feed digestibility, water balance, and fecal particle size in horses. | OBJECTIVE: To determine whether occlusal angle of the premolar and molar teeth (ie, molar occlusal angle) was associated with feed digestibility, water balance, or fecal particle size in adult horses.DESIGN: Observational study.ANIMALS: 40 pregnant mares ranging from 3 to 19 years old.PROCEDURE: The horses were randoml... | ['Animals', 'Dental Occlusion', 'Dentistry', 'Digestion', 'Feces', 'Female', 'Horses', 'Malocclusion', 'Mastication', 'Molar', 'Particle Size', 'Pregnancy', 'Random Allocation', 'Water-Electrolyte Balance'] | 16,013,545 | [['B01.050'], ['E06.276', 'G10.549.208'], ['E06', 'H02.163'], ['G07.203.650.250', 'G10.261.190'], ['A12.459'], ['B01.050.150.900.649.313.984.235.472'], ['C07.793.494'], ['G07.203.650.283.500', 'G10.261.330.500'], ['A14.549.167.860.525'], ['G02.712'], ['G08.686.784.769'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Furosemide reveals heterogeneous GABA(A) receptor expression at adult rat Golgi cell to granule cell synapses. | The contribution that alpha6 subunit-containing GABA(A) receptors make to inhibitory synaptic transmission to granule cells was investigated by making whole-cell patch clamp recordings from granule cells in adult rat cerebellar slices and applying furosemide, the specific alpha6 subunit-containing GABA(A) receptor anta... | ['Animals', 'Cerebellum', 'Cytoplasmic Granules', 'Diuretics', 'Electrophysiology', 'Excitatory Postsynaptic Potentials', 'Furosemide', 'In Vitro Techniques', 'Male', 'Membrane Potentials', 'Patch-Clamp Techniques', 'Rats', 'Rats, Wistar', 'Receptors, GABA-A', 'Synapses', 'Synaptic Transmission', 'gamma-Aminobutyric Ac... | 12,367,619 | [['B01.050'], ['A08.186.211.132.810.428.200'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['D27.505.696.560.500'], ['H01.158.344.528', 'H01.158.782.236'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['D02.065.884.725.300', 'D02.09... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Trifactorial classification system for osteotome sinus floor elevation based on an observational retrospective analysis of 926 implants followed up to 10 years. | OBJECTIVE: A novel osteotome trifactorial classification system is proposed for transcrestal osteotome-mediated sinus floor elevation (OSFE) sites that includes residual bone height (RBH), sinus floor anatomy (contour), and multiple versus single sites OSFE (tenting).METHOD AND MATERIALS: An analysis of RBH, contour, a... | ['Adult', 'Dental Implantation, Endosseous', 'Dental Implants', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Osteotomy', 'Outcome and Process Assessment, Health Care', 'Retrospective Studies', 'Sinus Floor Augmentation'] | 25,918,758 | [['M01.060.116'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Alpha(1) adrenoceptor subtype selectivity. 3D-QSAR models for a new class of alpha(1) adrenoceptor antagonists derived from the novel antipsychotic sertindole. | Receptor-binding affinities for the alpha(1) adrenoceptor subtypes alpha(1a), alpha(1b) and alpha(1d) for a series of 39 alpha(1) adrenoceptor antagonists derived from the antipsychotic sertindole are reported. The SAR of the compounds with respect to affinity for the alpha(1a), alpha(1b) and alpha(1d) adrenoceptor sub... | ['Adrenergic alpha-1 Receptor Antagonists', 'Drug Design', 'Imidazoles', 'Indoles', 'Models, Molecular', 'Quantitative Structure-Activity Relationship'] | 12,676,239 | [['D27.505.519.625.050.200.100.100', 'D27.505.696.577.050.200.100.100'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D03.383.129.308'], ['D03.633.100.473'], ['E05.599.595'], ['G02.111.830.500', 'G07.690.773.997.500']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Essential and nonessential metal effects on extracellular Leishmania amazonensis in vitro. | Protozoan parasites like Leishmania amazonensis are excellent models to test the effects of new drugs against a functional molecular arsenal used to establish successfully an infection in the vertebrate host, where they invade the cells of the monocytic system. However, little is known about the influence of metal ions... | ['Cadmium Chloride', 'Chlorides', 'Humans', 'Inhibitory Concentration 50', 'Leishmania mexicana', 'Mercuric Chloride', 'Microscopy, Electron, Transmission', 'Zinc Compounds'] | 31,881,207 | [['D01.142.175', 'D01.210.450.150.125'], ['D01.210.450.150', 'D01.248.497.158.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690.936.563'], ['B01.268.475.868.488.410'], ['D01.210.450.150.525', 'D01.538.500'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['D01.975']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel de novo 1.8 Mb microdeletion of 17q21.33 associated with intellectual disability and dysmorphic features. | We report on a de novo 17q21.33 microdeletion, 1.8 Mb in size, detected in a patient with mild intellectual disability, growth retardation, poor weight gain, microcephaly, long face, large beaked nose, thick lower lip, micrognathia and other dysmorphic features. The deletion was detected by whole-genome genotyping Bead... | ['Abnormalities, Multiple', 'Adolescent', 'Calcium Channels, T-Type', 'Chromosome Deletion', 'Chromosomes, Human, Pair 17', 'Craniofacial Abnormalities', 'Extracellular Matrix Proteins', 'Facies', 'Humans', 'Intellectual Disability', 'Male', 'Microcephaly', 'Muscular Atrophy', 'Nerve Tissue Proteins', 'Smith-Magenis Sy... | 22,842,074 | [['C16.131.077'], ['M01.060.057'], ['D12.776.157.530.400.150.720', 'D12.776.543.550.450.150.720', 'D12.776.543.585.400.150.720'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187.520.300.415.425', 'G05.3... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of metoclopramide on the growth hormone response to galanin in normal man. | One of the most prominent metabolic effects of the systemic administration of the synthetic neuropeptide galanin in man is the increase in growth hormone (GH) secretion. This stimulating action of galanin is thought to occur directly at the hypothalamic level through the release of GHRH. Recently, it has been shown tha... | ['Adult', 'Animals', 'Dopamine', 'Female', 'Galanin', 'Growth Hormone', 'Humans', 'Immunoradiometric Assay', 'Male', 'Metoclopramide', 'Neuropeptides', 'Peptides', 'Swine'] | 7,693,566 | [['M01.060.116'], ['B01.050'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D12.644.400.250', 'D12.776.631.650.250'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.639.405', 'E05.601.470.639.405'], ['D02.065... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A comparative study of the effect of the intrusion arch and straight wire mechanics on incisor root resorption: A randomized, controlled trial. | OBJECTIVE: To analyze and compare external apical root resorption (EARR) of maxillary incisors treated by intrusion arch or continuous archwire mechanics.MATERIALS AND METHODS: This cone-beam computed tomography (CBCT) study analyzed 28 deep bite patients in the permanent dentition who were randomly divided into two gr... | ['Adolescent', 'Biomechanical Phenomena', 'Cone-Beam Computed Tomography', 'Female', 'Humans', 'Incisor', 'Male', 'Maxilla', 'Overbite', 'Prospective Studies', 'Radiographic Image Interpretation, Computer-Assisted', 'Root Resorption', 'Software', 'Tooth Movement Techniques', 'Treatment Outcome', 'Young Adult'] | 28,985,106 | [['M01.060.057'], ['G01.154.090', 'G01.374.089'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.860.425'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['C07.793.494.630.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Mutational alterations of translational coupling in the L11 ribosomal protein operon of Escherichia coli. | The L11 operon in Escherichia coli consists of the genes coding for ribosomal proteins L11 and L1. It is known that translation of L1 does not take place unless the preceding L11 cistron is translated, that is, the two cistrons are translationally coupled, and this is the basis of coregulation of the translation of the... | ['Bacterial Proteins', 'Chromosome Deletion', 'Escherichia coli', 'Mutation', 'Operon', 'Plasmids', 'Protein Biosynthesis', 'Ribosomal Proteins'] | 3,301,803 | [['D12.776.097'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.365.590'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G05.360.600'], ['G02.11... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Workplace bullying in health care affects the meaning of work. | Our purpose in this grounded theory study was to explore the impact of workplace bullying (WPB) on women working in health care. We analyzed interviews with 21 women, professionals and nonprofessionals. The women experienced a change in their meaning of work (MOW) when they had experienced WPB, and they addressed this ... | ['Adaptation, Psychological', 'Adult', 'Aggression', 'Female', 'Health Personnel', 'Humans', 'Job Satisfaction', 'Knowledge', 'Middle Aged', 'Philosophy', 'Stress, Psychological', 'Violence', "Women's Health", 'Young Adult'] | 20,463,362 | [['F01.058'], ['M01.060.116'], ['F01.145.126.125', 'F01.145.813.045'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['K01.468'], ['M01.060.116.630'], ['K01.752'], ['F01.145.126.990', 'F02.830.900'], ['I01.198.240.856', 'I01.880.735.900'], ['N01.400.900'], ['M01.060.1... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Advantages of sentence-level fMRI language tasks in presurgical language mapping for temporal lobe epilepsy. | fMRI language mapping has become increasingly utilized for determining language dominance before surgical intervention for temporal lobe epilepsy (TLE). This study aimed to examine the differences between two classes of fMRI word generation tasks used in our clinic: tasks using a single word cue, referred to as simple ... | ['Adult', 'Brain Mapping', 'Epilepsy', 'Epilepsy, Temporal Lobe', 'Female', 'Functional Laterality', 'Humans', 'Language', 'Language Tests', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Temporal Lobe'] | 24,534,479 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C10.228.140.490'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F04.711.513.240'], ['E01.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Combined effects of caffeine and alcohol on hemodynamics and coronary artery blood flow in dogs. | Alcohol intake is often followed by coffee drinking because of the universal acceptance of its sobering effect. Such effects were found inconsistent on motor functions. However, it is common belief that caffeine will antagonize the intoxicating effects of alcohol. The independent actions of caffeine and alcohol are wel... | ['Animals', 'Arrhythmias, Cardiac', 'Arteries', 'Blood Flow Velocity', 'Caffeine', 'Central Nervous System Depressants', 'Central Nervous System Stimulants', 'Coronary Circulation', 'Dogs', 'Drug Administration Schedule', 'Drug Interactions', 'Ethanol', 'Hemodynamics'] | 9,890,396 | [['B01.050'], ['C14.280.067', 'C23.550.073'], ['A07.015.114'], ['E01.370.370.130', 'G09.330.380.630.080'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D27.505.696.277', 'D27.505.954.427.210'], ['D27.505.696.282', 'D27.505.954.427.220'], ['G09.330.100.324'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.3... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Integrated microHall magnetometer to measure the magnetic properties of nanoparticles. | Magnetic nanoparticles (MNPs) are widely used in biomedical and clinical applications, including medical imaging, therapeutics, and biological sample processing. Rapid characterization of MNPs, notably their magnetic moments, should facilitate optimization of particle synthesis and accelerate assay development. Here, w... | ['Cell Line, Tumor', 'Equipment Design', 'Humans', 'Lab-On-A-Chip Devices', 'Magnetite Nanoparticles', 'Magnetometry', 'Metals'] | 29,067,383 | [['A11.251.210.190', 'A11.251.860.180'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.343.500'], ['J01.637.512.600.500.144.500'], ['E05.540'], ['D01.552']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor. | Cylindromas are benign adnexal skin tumors caused by germline mutations in the CYLD gene. In most cases the second wild-type allele is lost in tumor tissue, suggesting that CYLD functions as tumor suppressor. CYLD is a protein of 956 amino acids harboring a functional deubiquitinating domain at the COOH-terminal end. T... | ['Animals', 'COS Cells', 'Deubiquitinating Enzyme CYLD', 'HeLa Cells', 'Humans', 'NF-kappa B', 'RNA-Binding Proteins', 'Receptors, Tumor Necrosis Factor', 'Signal Transduction', 'Tumor Necrosis Factor Receptor-Associated Peptides and Proteins', 'Tumor Necrosis Factor-alpha', 'Tumor Suppressor Proteins'] | 14,676,304 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D08.811.037.375', 'D12.776.624.776.482'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['D12.776.157.725', 'D12.776.664... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thyroid stimulating hormone assay as the first line biochemical parameter to determine thyroid gland abnormalities. | Increased cellular catabolic activities observed in hyperthyroid state had been established. This is consequent to excessive hormones secreted by the thyroid gland during this condition. A total of 60 subjects comprising of 45 females mean age 43.02 +/- 1.90 (range 22-70 years) and 15 males mean age 50.40 +/- 3.59 (ran... | ['Adult', 'Aged', 'Blood Chemical Analysis', 'Female', 'Humans', 'Hyperthyroidism', 'Male', 'Middle Aged', 'Sex Factors', 'Thyrotropin', 'Young Adult'] | 24,783,789 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.124.100', 'E05.200.124.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875'], ['D06.472.699.631.525.883', 'D12.644.548.691.525.883'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Kinematics after tear in the anterior cruciate ligament: dynamic bilateral radiostereometric studies in 11 patients. | We studied the kinematics of both knees using radiostereometry in 11 patients with unilateral injury of the anterior cruciate ligament and normal contralateral knee. Continuous radiostereometric exposures at a speed of 24 exposures a second were performed, when the patients ascended an 8 cm high platform. The tibial ce... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Chronic Disease', 'Female', 'Femur', 'Humans', 'Joint Instability', 'Knee Joint', 'Male', 'Photogrammetry', 'Radiography', 'Range of Motion, Articular', 'Risk Factors', 'Rotation', 'Rupture', 'Tibia', 'Weight-Bearing'] | 11,580,126 | [['M01.060.057'], ['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['C23.550.291.500'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['A02.835.583.475'], ['E01.370.350.600.630'], ['E01.370.350.700'], ['E01.370.600.700'... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Low-dose CT perfusion imaging based on pre-scan regulation and on reconstruction with sparsity constraints]. | The long-period CT perfusion imaging leads to an excess amount of radiation dose to the patient. However, the radiation dose could be significantly reduced if a previous normal-dose image is acquired before a set of low-dose scans of perfusion, and a filtering processing is performed on the differences between the curr... | ['Algorithms', 'Brain', 'Humans', 'Perfusion Imaging', 'Radiation Dosage', 'Radiation Injuries', 'Radiographic Image Interpretation, Computer-Assisted', 'Subtraction Technique', 'Tomography, X-Ray Computed'] | 22,403,999 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.710.600', 'E01.370.384.730.354'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E01.158.600.680', 'E01.370.350.350.700', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
In-gel microwave-assisted acid hydrolysis of proteins combined with liquid chromatography tandem mass spectrometry for mapping protein sequences. | We report an enabling method for mapping the protein sequence with high sequence coverage. This method combines the high separation power of gel electrophoresis for protein separation with the high sequence coverage capability of microwave-assisted acid hydrolysis (MAAH) mass spectrometry (MS). In-gel MAAH using 25% tr... | ['Animals', 'Caseins', 'Cattle', 'Chromatography, Liquid', 'Chromosome Mapping', 'Electrophoresis, Gel, Two-Dimensional', 'Humans', 'Hydrolysis', 'Microwaves', 'Serum Albumin', 'Tandem Mass Spectrometry'] | 24,308,638 | [['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400'], ['E05.393.183'], ['E05.196.401.250', 'E05.301.300.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of Pseudomonas stutzeri NT-I capable of removing soluble selenium from the aqueous phase under aerobic conditions. | Pseudomonas stutzeri strain NT-I was isolated from the drainage wastewater of a selenium refinery plant. This bacterium efficiently reduced selenate to elemental selenium without prolonged accumulation of selenite under aerobic conditions. Strain NT-I was able to reduce selenate completely at high concentrations (up to... | ['Industrial Waste', 'Oxidation-Reduction', 'Oxidoreductases', 'Pseudomonas stutzeri', 'Selenium', 'Water Microbiology'] | 21,676,651 | [['D20.944.420', 'N06.850.460.710.420'], ['G02.700', 'G03.295.531'], ['D08.811.682'], ['B03.440.400.425.625.625.750', 'B03.660.250.580.590.750'], ['D01.268.185.850', 'D01.578.700'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Amphiphilic pyridinium salts block TNF alpha/NF kappa B signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells. | Cystic fibrosis (CF) is a common, lethal genetic disease, which is due to mutations in the CFTR gene. The CF lung expresses a profoundly proinflammatory phenotype, due to constitutive hypersecretion of IL-8 from epithelial cells lining the airways. In a systematic search for candidate drugs that might be used therapeut... | ['Cystic Fibrosis', 'Dose-Response Relationship, Drug', 'HeLa Cells', 'Humans', 'Interleukin-8', 'NF-kappa B', 'Pyridinium Compounds', 'Respiratory Mucosa', 'Salts', 'Signal Transduction', 'Surface-Active Agents', 'Tumor Necrosis Factor-alpha'] | 15,963,954 | [['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D12.776.467.374.200.120.800', 'D12.776.467.37... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Emergency management of hypercyanotic crises in tetralogy of Fallot. | We report the case of a 3-month-old girl with tetralogy of Fallot who was resuscitated from a near-fatal hypercyanotic episode (Tet spell). While tetralogy of Fallot is rare (1 in 10,000 live births), failures of diagnosis or management may result in catastrophic outcomes for an eminently survivable condition. An under... | ['Aorta, Abdominal', 'Constriction', 'Cyanosis', 'Emergencies', 'Female', 'Humans', 'Infant', 'Oxygen', 'Tetralogy of Fallot'] | 7,832,359 | [['A07.015.114.056.205'], ['E05.225'], ['C23.888.248'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D01.268.185.550', 'D01.362.670'], ['C14.240.400.849', 'C14.280.400.849', 'C16.131.240.400.849']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of a singleplex PCR assay for rapid identification and differentiation of Cryptococcus neoformans var. grubii, Cryptococcus neoformans var. neoformans, Cryptococcus gattii, and hybrids. | A singleplex PCR assay using a single primer pair targeting the putative sugar transporter gene was developed here to distinguish Cryptococcus neoformans var. grubii, Cryptococcus neoformans var. neoformans, and Cryptococcus gattii according to the distinct size of the amplicon. The interspecies and intravarietal hybri... | ['Cryptococcosis', 'Cryptococcus gattii', 'Cryptococcus neoformans', 'DNA Primers', 'DNA, Fungal', 'Humans', 'Microbiological Techniques', 'Molecular Diagnostic Techniques', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Recombination, Genetic', 'Sequence Analysis, DNA', 'Time Factors'] | 23,536,400 | [['C01.150.703.248'], ['B01.300.381.258.300', 'B01.300.930.316.300'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875', 'E05.200.875'], ['E01.370.225.880', 'E05.200.880', '... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fatal neuroleptic malignant syndrome in a previously long-term user of clozapine following its reintroduction in combination with paroxetine. | A 77-year-old patient with initial behavioral and psychological symptoms of dementia was treated with clozapine (50 mg/daily). Since no clinical benefit was apparent, clozapine was discontinued after six weeks and the patient started on paroxetine (20 mg/daily). After three weeks on paroxetine, he was given another tri... | ['Aged', 'Antipsychotic Agents', 'Clozapine', 'Drug Therapy, Combination', 'Fatal Outcome', 'Humans', 'Male', 'Neuroleptic Malignant Syndrome', 'Paroxetine', 'Serotonin Uptake Inhibitors'] | 16,804,375 | [['M01.060.116.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D03.633.300.240.220'], ['E02.319.310'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. | PURPOSE: Glioblastoma is an incurable solid tumor characterized by increased expression of vascular endothelial growth factor (VEGF). We performed a phase II study of cediranib in patients with recurrent glioblastoma.METHODS: Cediranib, an oral pan-VEGF receptor tyrosine kinase inhibitor, was administered (45 mg/d) unt... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Biomarkers, Tumor', 'Brain Neoplasms', 'Disease-Free Survival', 'Female', 'Glioblastoma', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Protein Kinase Inhibitors', 'Quinazolines', 'Receptors, Vascular Endothelial Growth Factor', 'Young Adult'] | 20,458,050 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['D23.101.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C04.557.465.625.600.38... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Double loss-of-function mutation in EARLY FLOWERING 3 and CRYPTOCHROME 2 genes delays flowering under continuous light but accelerates it under long days and short days: an important role for Arabidopsis CRY2 to accelerate flowering time in continuous light. | The photoperiodic response is one of the adaptation mechanisms to seasonal changes of lengths of day and night. The circadian clock plays pivotal roles in this process. In Arabidopsis, LHY, CCA1, ELF3, and other clock proteins play major roles in maintaining circadian rhythms. lhy;cca1 double mutants with severe defect... | ['Alleles', 'Arabidopsis', 'Arabidopsis Proteins', 'Cryptochromes', 'Flowers', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genes, Suppressor', 'Hypocotyl', 'Light', 'Models, Biological', 'Mutation', 'Phenotype', 'Photoperiod', 'Repressor Proteins', 'Suppression, Genetic', 'Time Factors', 'Transcription Factor... | 21,296,763 | [['G05.360.340.024.340.030'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D12.644.360.138.150', 'D12.776.331.180', 'D12.776.476.156.250', 'D12.776.765.593.500'], ['A18.024.249.500'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.024.340.460'], ['A18.024.875.750',... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The impact of percutaneous tracheostomy on intensive care unit practice and training. | We studied the impact of introducing percutaneous tracheostomy to our intensive care unit on the incidence and timing of tracheostomy and on the implications for surgical training. The proportion of patients receiving intensive care who underwent tracheostomy doubled from a median of 8.5% to 16.8% (p < 0.01) following ... | ['Critical Care', 'Education, Medical, Graduate', 'England', 'General Surgery', 'Humans', 'Medicine', 'Retrospective Studies', 'Specialization', 'Time Factors', 'Tracheostomy', 'Workload'] | 10,215,717 | [['E02.760.190', 'N02.421.585.190'], ['I02.358.337.350', 'I02.358.399.350'], ['Z01.542.363.300'], ['H02.403.810.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Developmental regulation of RNA editing and polyadenylation in four life cycle stages of Trypanosoma congolense. | The accumulation of many edited mRNAs is developmentally regulated in a transcript-specific fashion in Trypanosoma brucei. In addition, these transcripts are frequently present in two size classes which differ substantially in the lengths of their poly(A) tails, and poly(A) tail length is also developmentally regulated... | ['Animals', 'Apoproteins', 'Blotting, Northern', 'Cytochrome b Group', 'Cytochromes b', 'Gene Expression Regulation, Developmental', 'Mitochondria', 'NADH Dehydrogenase', 'Poly A', 'RNA Editing', 'RNA, Messenger', 'RNA, Protozoan', 'Trypanosoma brucei brucei', 'Trypanosoma congolense'] | 7,739,675 | [['B01.050'], ['D12.776.070'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D08.244.187', 'D12.776.422.220.187'], ['D08.244.187.249', 'D12.776.422.220.187.249'], ['G05.308.310'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D08.811.682.608.504.500', 'D12.776.157.427.374.375.863.500', 'D12.776.331.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sickness presenteeism predicts suboptimal self-rated health and sickness absence: a nationally representative study of the Swedish working population. | BACKGROUND: Earlier studies have suggested that sickness presenteeism (SP) may be a risk factor for future health problems. The purpose of the present study was to test this in a nationally representative prospective study of Swedish workers.METHODS: Prospective cohort with a representative sample of the Swedish workin... | ['Absenteeism', 'Adult', 'Cohort Studies', 'Female', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Occupational Health', 'Odds Ratio', 'Prospective Studies', 'Regression Analysis', 'Risk Factors', 'Sick Leave', 'Surveys and Questionnaires', 'Sweden'] | 22,984,547 | [['F02.784.692.107'], ['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N01.400.525'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Morbidity and healthcare utilisation of children in households with one adult: comparative observational study. | OBJECTIVE: To identify and consider differences in morbidity in children in households with one adult presenting to general practitioners compared with children in households with more than one adult.DESIGN: Observational study; data analysed with logistic regression controlling for age, sex, and practice.SUBJECTS: 93 ... | ['Adolescent', 'Adult', 'Child', 'Child Health Services', 'Child, Preschool', 'Family Practice', 'Female', 'House Calls', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Morbidity', 'Multivariate Analysis', 'Patient Acceptance of Health Care', 'Rural Health', 'Single Parent', 'Social Class', 'United Kingdom', 'Urban He... | 9,596,597 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['N02.421.143.130'], ['M01.060.406.448'], ['H02.403.340.500'], ['N04.452.758.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.308.985.525', 'N01.224.935.597', 'N06.850.505.400.975.525', 'N06.850.520.308.985.525'],... | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
MYO6 is targeted by Salmonella | To establish infections, Salmonella injects virulence effectors that hijack the host actin cytoskeleton and phosphoinositide signaling to drive pathogen invasion. How effectors reprogram the cytoskeleton network remains unclear. By reconstituting the activities of the Salmonella effector SopE, we recapitulated Rho GTPa... | ['Bacterial Proteins', 'Cell Membrane', 'Cytoskeleton', 'HeLa Cells', 'Host-Pathogen Interactions', 'Humans', 'Microfilament Proteins', 'Myosin Heavy Chains', 'Phosphatidylinositol 3-Kinase', 'Phosphatidylinositols', 'Salmonella typhimurium', 'Signal Transduction', 'Virulence Factors'] | 28,348,208 | [['D12.776.097'], ['A11.284.149'], ['A11.284.430.214.190.750'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.730', 'D12.776.220.525'], ['D05.750.078.730.475.100', 'D08.811.277.040.025.193.750.249', 'D12.776.210.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biologically active dichapetalins from Dichapetalum gelonioides. | A phytochemical investigation of the toxic tropical plant Dichapetalum gelonioides led to the isolation and identification of 14 new dichapetalins (1-14) and the known dichapetalins A (15) and K (16). The structures of the new compounds were determined by analyses of their NMR, MS, electronic circular dichroism, and X-... | ['Antifungal Agents', 'Antinematodal Agents', 'Antineoplastic Agents', 'Cholinesterase Inhibitors', 'Feeding Behavior', 'Heterocyclic Compounds, 4 or More Rings', 'Magnoliopsida', 'Molecular Structure', 'Nitric Oxide', 'Spiro Compounds', 'Triterpenes'] | 24,597,894 | [['D27.505.954.122.136'], ['D27.505.954.122.250.075.080'], ['D27.505.954.248'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D03.633.400'], ['B01.650.940.800.575.912.250'], ['G02.111.570', 'G02.466'], ['D01.339.387', 'D01.625.550... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Case of Cap Polyposis with Epidermal Nevus in an Infant. | Cap polyposis is extremely rare in children. We report a case of an 11-month-old male infant who visited our hospital because of rectal prolapse and small amount of hematochezia lasting several days. He also had an epidermal nevus in the sacral area. Colonoscopy showed erythematous, multilobulated, circumferential, pol... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Colonic Polyps', 'Colonoscopy', 'Humans', 'Infant', 'Male', 'Mesalamine', 'Nevus', 'Polyps', 'Rectal Diseases', 'Rectum', 'Tomography, X-Ray Computed'] | 28,378,565 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C23.300.825.411.235'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D02.241.223.100.050.300.500', 'D0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
provider venture capital funds: investing in innovation. | As health systems continue to embrace disruptive innovation, they are increasingly likely to consider making a move into venture capital. Working in venture capital can benefit a health system in several ways, including: Allowing it to operate outside of bureaucracy and align projects with its core values. Encouraging ... | ['Capital Financing', 'Delivery of Health Care', 'Financial Management', 'Humans', 'Organizational Innovation', 'United States'] | 27,382,708 | [['N03.219.463.085'], ['N04.590.374', 'N05.300'], ['N03.219.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.610'], ['Z01.107.567.875']] | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Composite-bonded bridges reinforced with Ribbond THM ribbon: an alternative of choice to other temporary prosthetic methods]. | In the presence of anterior unitary tooth loss, the therapeutical arsenal of the practitioner remains the implant solution. But, at the young patients who have not completed their growth, it's necessary to pass by a transitional stage. The bonded bridges reinforced by a polyethylene fibbers splint such as Ribbond THM c... | ['Adolescent', 'Composite Resins', 'Dental Materials', 'Denture, Partial, Fixed, Resin-Bonded', 'Denture, Partial, Temporary', 'Esthetics, Dental', 'Female', 'Humans', 'Incisor', 'Polyethylenes', 'Tooth Loss'] | 15,074,071 | [['M01.060.057'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['D25.339', 'D27.720.102.339', 'J01.637.051.339'], ['E06.780.346.760.943.271.260', 'E07.695.190.200.220.220.220'], ['E06.780.346.760.943.484', 'E07.695.190.200.220.235'], ['E06.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Urethral advancement, glanduloplasty and preputioplasty in distal hypospadias. | One hundred and thirty boys with subcoronal (78) and subglandular (52) hypospadias were submitted to Urethral Advancement, Glanduloplasty and Preputioplasty (URAGP). The main steps of the operation were the following: blunt dissection and mobilization of the urethra as extensively as needed to reach the tip of the glan... | ['Child', 'Child, Preschool', 'Humans', 'Hypospadias', 'Male', 'Penis', 'Postoperative Complications', 'Suture Techniques', 'Treatment Outcome', 'Urethra'] | 8,773,225 | [['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494.400', 'C12.706.516', 'C13.351.875.466', 'C16.131.939.516'], ['A05.360.444.492'], ['C23.550.767'], ['E04.987.775'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['A05.360.444.492.726', 'A05.810.876... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Childhood IQ predicts age-38 oral disease experience and service-use. | OBJECTIVES: Given that people with higher intelligence have been shown to live longer, enjoy better health and have more favourable health behaviours, we investigated the association between childhood IQ and a range of important dental health and service-use indicators at age 38.METHODS: Long-standing prospective study... | ['Adolescent', 'Adult', 'Child', 'Dental Care', 'Dental Caries', 'Humans', 'Intelligence', 'Oral Health', 'Periodontal Diseases', 'Prospective Studies'] | 30,812,053 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E06.170', 'N02.421.240.190'], ['C07.793.720.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['N01.400.535'], ['C07.465.714'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endothelin-1 gene and endothelial nitric oxide synthase gene polymorphisms in adolescents with juvenile and obesity-associated hypertension. | Hypertension is an increasing public health problem all over the world. Essential hypertension accounts for more than 90% of cases of hypertension. It is a complex genetic, environmental and demographic trait. New method in molecular biology has been proposed a number of candidate genes, but the linkage or association ... | ['Adolescent', 'Body Mass Index', 'Child', 'Endothelin-1', 'Gene Frequency', 'Humans', 'Hypertension', 'Male', 'Nitric Oxide Synthase Type III', 'Nitrogen Oxides', 'Obesity', 'Polymorphism, Genetic'] | 17,444,275 | [['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['G05.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D08.811.682.664.500.772.750'], ['D01.362.63... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
TP53 | Emergency (stress) granulopoiesis is an episodic process for the production of granulocytes in response to infectious challenge. We previously determined that Fanconi C, a component of the Fanconi DNA-repair pathway, is necessary for successful emergency granulopoiesis. Fanconi anemia results from mutation of any gene ... | ['Animals', 'Apoptosis', 'Ataxia Telangiectasia Mutated Proteins', 'Bone Marrow', 'DNA Damage', 'DNA Repair', 'Fanconi Anemia', 'Fanconi Anemia Complementation Group C Protein', 'Granulocytes', 'Haploinsufficiency', 'Leukopoiesis', 'Mice', 'Tumor Suppressor Protein p53'] | 29,427,417 | [['B01.050'], ['G04.146.954.035'], ['D08.811.913.696.620.682.700.097', 'D12.776.157.687.125', 'D12.776.660.720.125'], ['A15.382.216'], ['G05.200'], ['G02.111.222', 'G05.219'], ['C15.378.071.085.080.280', 'C15.378.190.223.500.500.280', 'C16.320.077.280', 'C18.452.284.280'], ['D12.776.313.750'], ['A11.118.637.415', 'A11.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An open-label study assessing the safety and efficacy of alitretinoin in patients with severe chronic hand eczema unresponsive to topical corticosteroids. | BACKGROUND: Blinded, controlled studies have found that oral alitretinoin is well tolerated and effective in the treatment of severe chronic hand eczema (CHE).AIM: To assess the safety and efficacy of oral alitretinoin in patients with severe CHE in an open-label study using flexible dosing and a new measurement of pat... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Alitretinoin', 'Chronic Disease', 'Dermatologic Agents', 'Drug Administration Schedule', 'Female', 'Glucocorticoids', 'Hand Dermatoses', 'Humans', 'Male', 'Middle Aged', 'Severity of Illness Index', 'Treatment Failure', 'Treatment Outcome', 'Tretinoin', 'Young Ad... | 21,070,335 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D02.455.326.271.665.202.495.818.500.500', 'D02.455.426.392.368.367.379.249.700.860.500.500', 'D02.455.849.131.495.818.800.500', 'D02.455.849.291.925.500.500', 'D23.767.261.700.780.500'], ['C23.550.291.500'], ['D27.505.954.444'], ['E02.319.28... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Covalent immobilization of recombinant organophosphorus hydrolase on spores of Bacillus subtilis. | AIMS: Organophosphorus pesticides are widely used in agriculture. Accordingly, decontamination of these pesticides and their residual in environment is an important aim of researchers. One of the best approaches is enzymatic detoxification of these compounds with organophosphorus hydrolase (OPH). The immobilization of ... | ['Aryldialkylphosphatase', 'Bacillus subtilis', 'Enzymes, Immobilized', 'Organophosphorus Compounds', 'Paraoxon', 'Pesticides', 'Recombinant Proteins', 'Spectroscopy, Fourier Transform Infrared', 'Spores, Bacterial'] | 25,565,038 | [['D08.811.277.352.660.500'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D08.811.180', 'D12.776.463.500'], ['D02.705'], ['D02.705.400.650'], ['D27.720.031.700', 'D27.888.723'], ['D12.776.828'], ['E05.196.712.726.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relational diagnosis: a coconstructive-developmental perspective on assessment and treatment. | As we expand the borders of traditional diagnostic nomenclature, distinguishing health from disorder becomes complex. This is especially true when the diagnostic lens views individuals as they exist within families that reside within wider social milieus. From this viewpoint, the recursive and interdependent factors in... | ['Adolescent', 'Adult', 'Child', 'Cognitive Behavioral Therapy', 'Family Therapy', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Mental Disorders', 'Psychiatric Status Rating Scales', 'Psychotherapy', 'Systems Theory'] | 10,946,730 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['F04.754.137.350'], ['F04.754.864.581.273'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F03'], ['F04.711.513.653'], ['F04.754'], ['H01.770.808']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Subclinical hyperthyroid patients' knowledge about radioiodine therapy--the key role of medical information. | OBJECTIVES: Many patients with a chronic disease are dissatisfied with the information they are given. A brief questionnaire completed by patients would assist health professionals to identify areas of information needed to be provided, tailored to the patient's mental condition.AIM: The aim of our study was to assess ... | ['Adult', 'Aged', 'Depression', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Hyperthyroidism', 'Informed Consent', 'Iodine Radioisotopes', 'Male', 'Middle Aged', 'Patients', 'Poland', 'Surveys and Questionnaires', 'Treatment Outcome', 'Young Adult'] | 21,196,911 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.126.350'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[An Examination of Colon Cancer Treatment Policies for the Elderly]. | Currently, the rate of aging is increasing rapidly and the number of elderly patients in hospitals is rising in Japan. Under such circumstances, we established an emergency care unit for the elderly at our hospital in July 2014 to provide acute healthcare of the community. Our unit has been active in providing treatmen... | ['Aged', 'Aged, 80 and over', 'Colectomy', 'Colonic Neoplasms', 'Dementia', 'Female', 'Humans', 'Male', 'Prognosis'] | 28,133,044 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.219'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Status of New Vaccine Introduction - Worldwide, September 2016. | Since the global Expanded Program on Immunization (EPI) was launched in 1974, vaccination against six diseases (tuberculosis, polio, diphtheria, tetanus, pertussis, and measles) has prevented millions of deaths and disabilities (1). Significant advances have been made in the development and introduction of vaccines, an... | ['Adolescent', 'Bacterial Capsules', 'Child', 'Child, Preschool', 'Female', 'Global Health', 'Haemophilus Vaccines', 'Hepatitis B Vaccines', 'Humans', 'Immunization Programs', 'Immunization Schedule', 'Infant', 'Infant, Newborn', 'Measles Vaccine', 'Papillomavirus Vaccines', 'Pneumococcal Vaccines', 'Rotavirus Vaccines... | 27,764,083 | [['M01.060.057'], ['A20.186'], ['M01.060.406'], ['M01.060.406.448'], ['H02.403.371', 'N01.400.337'], ['D20.215.894.135.450'], ['D20.215.894.899.955.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.608'], ['E02.095.465.425.400.470', 'E05.478.550.545'], ['M01.060.703'], ['M01.060.703.520'], ['D20.215... | ['Named Groups [M]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Vulnerability to AIDS among the elderly in an urban center in central Brazil. | OBJECTIVE: As the world population ages with an improved quality of life and sexual longevity, the prevalence of AIDS is rising among the elderly. The purpose of this study was to estimate the vulnerability to AIDS among individuals attending senior community centers in Campo Grande, Mato Grosso do Sul, Brazil.METHOD: ... | ['Aged', 'Brazil', 'Chi-Square Distribution', 'Condoms', 'Cross-Sectional Studies', 'Female', 'Geriatric Assessment', 'HIV Infections', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Sex Distribution', 'Sexual Behavior', 'Unsafe Sex', 'Urban Population', 'Vulnerable Populatio... | 22,249,476 | [['M01.060.116.100'], ['Z01.107.757.176'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E07.190.270.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Development-Dependent Changes in the NR2 Subtype of the N-Methyl-D-Aspartate Receptor in the Suprachiasmatic Nucleus of the Rat. | The suprachiasmatic nucleus (SCN) is the main brain clock that regulates circadian rhythms in mammals. The SCN synchronizes to the LD cycle through the retinohypothalamic tract (RHT), which projects to ventral SCN neurons via glutamatergic synapses. Released glutamate activates N-methyl-D-aspartate (NMDA) receptors, wh... | ['Aging', 'Animals', 'Brain', 'Circadian Rhythm', 'Rats', 'Rats, Wistar', 'Receptors, N-Methyl-D-Aspartate', 'Suprachiasmatic Nucleus Neurons', 'Synapses'] | 30,654,688 | [['G07.345.124'], ['B01.050'], ['A08.186.211'], ['G07.180.562.190'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D12.776.157.530.400.400.500.500', 'D12.776.543.550.450.500.200.500', 'D12.776.543.585.400.500.200.500', 'D12.776.543.750.720.200.450.400.500'], ['A08.186.2... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Application of strain and calibration of F?rster Resonance Energy Transfer (FRET) emission for in vitro live cell response to cytoskeletal deformation. | Cellular mechanotransduction is an integral part of many crucial physiological processes, but non-invasive tools for quantifying intracellular strain in vivo are not available for complex tissues such as bone. As a first step to address this gap, we have utilized a novel, non-invasive approach to quantify cellular stra... | ['Actinin', 'Animals', 'Biomechanical Phenomena', 'Calibration', 'Cell Survival', 'Cells, Cultured', 'Cytoskeleton', 'Female', 'Fluorescence Resonance Energy Transfer', 'Luminescent Proteins', 'Mechanotransduction, Cellular', 'Mice', 'Stress, Mechanical'] | 27,589,930 | [['D05.750.078.730.248', 'D12.776.210.500.095', 'D12.776.220.525.250'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['E05.978.155'], ['G04.346'], ['A11.251'], ['A11.284.430.214.190.750'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['D12.776.532'], ['G01.154.090.500', 'G02.111.820.580', 'G04... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combination of topotecan and cisplatin in relapsed patients with small cell lung cancer: a phase II study of the hellenic cooperative oncology group (HeCOG). | PURPOSE: To assess the safety and efficacy of a 3-day schedule of cisplatin and topotecan in patients with recurrent small-cell lung cancer (SCLC).METHODS: Thirty-four relapsed patients were treated with cisplatin 20 mg/m2 and topotecan 0.9 mg/m2, both given on days 1-3 every 3 weeks, in a phase II study.RESULTS: Compl... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Small Cell', 'Cisplatin', 'Drug Administration Schedule', 'Female', 'Humans', 'Infusions, Intravenous', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Survival Analysis', 'Topotecan', 'Treatment Outcome'] | 16,028,103 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.380'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['C04.588.894.797.520', 'C08.381.540... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structurally related Spc1p and Spc2p of yeast signal peptidase complex are functionally distinct. | Two subunits of the mammalian signal peptidase complex, SPC12 and SPC25, share similar membrane topologies with the majority of each protein oriented toward the cytoplasm. Such similarities may suggest that these proteins perform redundant functions in signal peptidase activity. In the present study, we addressed this ... | ['Amino Acid Sequence', 'Animals', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cloning, Molecular', 'Dogs', 'Fungal Proteins', 'Hot Temperature', 'Membrane Proteins', 'Mitogen-Activated Protein Kinases', 'Molecular Sequence Data', 'Mutation', 'Protein Precursors', 'Saccharomyces cerevisiae', 'Saccharomyces cerevis... | 8,910,564 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['E05.393.220'], ['B01.050.150.900.649.313.750.250.216.200'], ['D12.776.354'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Malinowski goes to college: factors influencing students' use of ritual and superstition. | Anthropologists have long noted that the use of ritual and magic is linked to conditions of risk and uncertainty. In this study, the authors examined how perceived task difficulty, participants' level of preparation, and the value of the outcome interact to influence the self-reporting of superstition and ritual. Colle... | ['Adolescent', 'Adult', 'Anthropology', 'Ceremonial Behavior', 'Female', 'Humans', 'Male', 'Psychological Theory', 'Students', 'Superstitions', 'Teaching', 'Universities'] | 18,183,736 | [['M01.060.057'], ['M01.060.116'], ['F04.096.879.201', 'I01.076'], ['F01.145.813.097', 'I01.076.201.450.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.739'], ['M01.848'], ['I01.076.201.450.897'], ['I02.903'], ['I02.783.830', 'J03.832.830']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
Citrobacter rodentium, the causative agent of transmissible murine colonic hyperplasia, exhibits clonality: synonymy of C. rodentium and mouse-pathogenic Escherichia coli. | Citrobacter rodentium (formerly Citrobacter freundii biotype 4280 and Citrobacter genomospecies 9) was described on the basis of biochemical characterization and DNA-DNA hybridization data and is the only Citrobacter species known to possess virulence factors homologous to those of the human pathogens enteropathogenic ... | ['Animals', 'Chromosome Mapping', 'Citrobacter freundii', 'Colonic Diseases', 'Escherichia coli', 'Female', 'Hyperplasia', 'Male', 'Mice', 'Polymerase Chain Reaction', 'Rodent Diseases', 'Virulence'] | 11,101,562 | [['B01.050'], ['E05.393.183'], ['B03.440.450.425.200.275', 'B03.660.250.150.100.210'], ['C06.405.469.158'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C23.550.444'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.620.500'], ['C22.795'], ['G06.930']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolongation of the prothrombin time after organophosphate poisoning. | Prolongation of the prothrombin time owing to a transient reduction in factor VII activity is described in a 14-month-old child with organophosphate poisoning. Correction after vitamin K administration suggested an organophosphate-related effect on vitamin K-dependent factor VII activity. Historically, coagulation scre... | ['Acetylcholinesterase', 'Factor VII', 'Female', 'Humans', 'Infant', 'Organophosphate Poisoning', 'Poisoning', 'Prothrombin Time', 'Vitamin K'] | 7,845,858 | [['D08.811.277.352.100.170.176'], ['D08.622.432', 'D12.776.124.125.325', 'D12.776.811.243.432', 'D23.119.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C25.723.717'], ['C25.723'], ['E01.370.225.625.115.610', 'E05.200.625.115.610', 'G09.188.680'], ['D02.455.426.559.847.638.721.374', 'D02.455.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis. | BACKGROUND: Adjunctive dexamethasone reduces mortality from tuberculous meningitis, but how it produces this effect is not known. Matrix metalloproteinases (MMPs) are important in the immunopathology of many inflammatory CNS diseases thus we hypothesized that that their secretion is important in TBM and might be influe... | ['Adult', 'Cerebrospinal Fluid', 'Chemotherapy, Adjuvant', 'Dexamethasone', 'Female', 'Glucocorticoids', 'Humans', 'Kinetics', 'Male', 'Matrix Metalloproteinase 9', 'Matrix Metalloproteinases', 'Middle Aged', 'Neutrophils', 'Placebos', 'Treatment Outcome', 'Tuberculosis, Meningeal'] | 19,789,647 | [['M01.060.116'], ['A12.207.270.210'], ['E02.186.170', 'E02.319.170'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.252... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fully intact contact heat evoked potentials in patients with amyotrophic lateral sclerosis. | Amyotrophic lateral sclerosis (ALS) is typically considered to be a disease of motor, not sensory, neurons. However, reports exist of sensory system involvement in ALS. In this study we aimed to study the characteristic of contact heat-evoked potentials (CHEPs) in patients with ALS and to evaluate the nociceptive pathw... | ['Adult', 'Afferent Pathways', 'Aged', 'Amyotrophic Lateral Sclerosis', 'Evoked Potentials, Somatosensory', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nerve Fibers, Unmyelinated', 'Neural Conduction', 'Nociceptors', 'Pain', 'Pain Measurement', 'Physical Stimulation', 'Reaction Time', 'Sensation Disorders', 'Sensory Re... | 19,260,053 | [['M01.060.116'], ['A08.612.220'], ['M01.060.116.100'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.675.542.756', 'A11.671.501.756'], ['G07... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chemical studies on the structure of mucopeptide isolated from Streptococcus bovis. | Mucopeptides isolated from Streptococcus bovis cell walls were found to be composed of alanine, glutamic acid, lysine, and threonine in a mole ratio of 3:1:1:1. A dipeptide, N(epsilon)-lysylthreonine, was isolated from S. bovis mucopeptide by ion-exchange chromatography. This finding suggests that threonine is associat... | ['Alanine', 'Cell Wall', 'Chromatography, Ion Exchange', 'Glucosamine', 'Glutamates', 'Lysine', 'Mucoproteins', 'Streptococcus', 'Threonine'] | 5,802,603 | [['D12.125.042'], ['A11.284.183'], ['E05.196.181.400.383'], ['D09.067.342.531'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['D12.776.395.560'], ['B03.353.750.737.872', 'B03.510.400.800.872', 'B03.510.550.737.872'], ['D12.125.142.815', 'D12.125.154.900']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three-dimensional CT modeling versus traditional radiology techniques in treatment of acetabular fractures. | Recently, the authors have used the computer-generated three-dimensional (3-D) CT moving images for preoperative planning and screw/pin insertion in more than 28 cases involving plate and screw fixation of complex acetabular fractures. The authors also used stereolithography (wax or plastic 3-D model of bony anatomy) t... | ['Acetabulum', 'Adult', 'Fractures, Bone', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Tomography, X-Ray Computed'] | 11,813,946 | [['A02.835.232.043.825.108'], ['M01.060.116'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Early pregnancy testing and its relationship to abortion. | A total of 487 Standardbred and Thoroughbred mares at two studs were manually tested for pregnancy at 20 to 24, 30 to 34, and greater than 42 days after service and the abortion rate compared to that obtained in previous years when only the greater than 42-day test was performed. The results indicated that early manual... | ['Abortion, Veterinary', 'Animals', 'Australia', 'Female', 'Horses', 'Palpation', 'Pregnancy', 'Pregnancy Tests', 'Pregnancy, Animal', 'Time Factors'] | 1,060,828 | [['C13.703.039.422', 'C22.021'], ['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.984.235.472'], ['E01.370.600.600'], ['G08.686.784.769'], ['E01.370.225.970', 'E01.370.378.620', 'E05.200.970'], ['G08.686.784.769.498'], ['G01.910.857']] | ['Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Macrophages as delivery vehicles for anticancer agents. | The delivery of anticancer agents via passive approaches such as the enhanced permeability and retention effect is unlikely to achieve sufficient concentrations throughout the tumor volume for effective treatment. Cell-based delivery approaches using tumor tropic cells have the potential to overcome the limitations of ... | ['Animals', 'Antigen-Presenting Cells', 'Antineoplastic Agents', 'Cytosine Deaminase', 'Humans', 'Macrophages', 'Nanoparticles', 'Neoplasms', 'Photosensitizing Agents', 'Phototherapy'] | 30,909,858 | [['B01.050'], ['A11.066', 'A15.382.066'], ['D27.505.954.248'], ['D08.811.277.151.486.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['J01.637.512.600'], ['C04'], ['D27.505.954.444.600', 'D27.505.954.600.710'], ['E02.774']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Smoking Lung Cancer Patients and Tobacco Cessation - Is the Current Treatment in Germany Sufficient? | Lung cancer is the most preventable neoplastic disease for men and women. The incidence rate per year is 14.000 in Germany. Smoking is the main risk factor for the onset of lung cancer and for a share of 90% of cases, lung cancer is associated with smoking. Recent studies have shown that the time slot of diagnosing lun... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Comorbidity', 'Female', 'Germany', 'Health Care Surveys', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Prevalence', 'Quality of Life', 'Retrospective Studies', 'Risk Factors', 'Sex Distribution', 'Smoking', 'Smoking Prevention', 'Tobacco Use Cessation', 'Treat... | 26,398,407 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['Z01.542.315'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Lipid and lipoprotein parameters for detection of familial hypercholesterolemia in childhood. The DECOPIN Project. | BACKGROUND: Familial hypercholesterolaemia (FH) in children is under-detected and is difficult to diagnose in clinical practice. The aim of this study was to evaluate clinical, biochemical and vascular imaging variables in order to detect children and adolescents with FH.METHODS: A total of 222 children aged 4-18 years... | ['Achilles Tendon', 'Adolescent', 'Apolipoprotein A-I', 'Apolipoprotein B-100', 'Carotid Intima-Media Thickness', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Humans', 'Hypercholesterolemia', 'Hyperlipoproteinemia Type II', 'Lipids', 'Male', 'Mutation', 'Sensit... | 29,602,595 | [['A02.880.176'], ['M01.060.057'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['D10.532.091.300.249', 'D12.776.070.400.300.249', 'D12.776.521.120.300.249'], ['E01.370.350.850.150', 'E01.370.370.180', 'G09.330.210'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preparation of folate-modified pullulan acetate nanoparticles for tumor-targeted drug delivery. | The purpose of this work was to develop a novel nano-carrier with targeting property to tumor. In this study, pullulan acetate (PA) was synthesized by the acetylation of pullulan to simplify the preparation technique of nanoparticles. Folic acid (FA) was conjugated to PA in order to improve the cancer-targeting activit... | ['Acetylation', 'Antibiotics, Antineoplastic', 'Cell Culture Techniques', 'Cell Survival', 'Drug Carriers', 'Drug Compounding', 'Endocytosis', 'Epirubicin', 'Flow Cytometry', 'Folic Acid', 'Glucans', 'Humans', 'KB Cells', 'Microscopy, Confocal', 'Microscopy, Electron, Transmission', 'Nanoparticles', 'Particle Size', 'S... | 22,747,075 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D27.505.954.248.106'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.346'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.270'], ['G04.417'], ['D02.455.426.559.847.562.050.200.175.200', 'D04.615.562.050.200.175.200', 'D09.40... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fashion advertisements: a comparison of viewers' perceptual and affective responses to illustrated and photographed stimuli. | The perceptual and affective responses of 44 women to actual illustrated and photographed fashion advertisements during focused interviews were explored. Content analysis methods identified categories of response; frequency of response categories for the two media were compared using Fisher's z tests. Significant diffe... | ['Adult', 'Advertising', 'Affect', 'Aged', 'Art', 'Female', 'Humans', 'Middle Aged', 'Perception', 'Periodicals as Topic', 'Photography'] | 1,484,770 | [['M01.060.116'], ['J01.219.687.274', 'L01.143.050'], ['F01.470.047'], ['M01.060.116.100'], ['K01.093'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593'], ['L01.178.682.829.678'], ['E01.370.350.600', 'E05.712']] | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
[Hypotension in Austria (author's transl)]. | A representative group of the Austrian population was surveyed to gain informations about various aspects of the blood pressure problem. 22% of the persons surveyed (16-70 years) reported hypotension and 14% hypertension. Especially women very often (29%) consider their blood pressure rather low. 17% of the respondents... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Attitude to Health', 'Austria', 'Female', 'Humans', 'Hypertension', 'Hypotension', 'Male', 'Middle Aged', 'Sex Factors'] | 7,257,424 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['Z01.542.088'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.907.514'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875']] | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
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