Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Altered â-catenin expression in oral mucosal dysplasia: a comparative study. | OBJECTIVE: The current study aimed to investigate the â-catenin expression in oral leukoplakia (OL) with different degrees of epithelial dysplasia and normal oral mucosa.MATERIAL AND METHODS: Formalin-fixed, paraffin-embedded tissue samples of 39 OL (mild dysplasia n=19, moderate dysplasia n=13, and severe dysplasia n=... | ['Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Cell Membrane', 'Epithelial Cells', 'Female', 'Humans', 'Immunohistochemistry', 'Leukoplakia, Oral', 'Male', 'Middle Aged', 'Mouth Mucosa', 'Paraffin Embedding', 'Reference Values', 'Severity of Illness Index', 'beta Catenin'] | 26,537,717 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.284.149'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Significant similarity and dissimilarity in homologous proteins. | Common practice emphasizes significant sequence similarities between different members of protein families. These similarities presumably reflect on evolutionary conservation of structurally and functionally essential residues. The nonconserved regions, on the other hand, may be either selectively neutral or differenti... | ['GTP-Binding Proteins', 'Herpesviridae', 'Neurofibromin 1', 'Proteins', 'Sequence Homology, Nucleic Acid', 'Statistics as Topic', 'Viral Proteins'] | 1,552,837 | [['D08.811.277.040.330.300', 'D12.776.157.325'], ['B04.280.382'], ['D12.644.360.325.150.500.460', 'D12.776.476.325.150.500.460', 'D12.776.624.776.610'], ['D12.776'], ['G02.111.810.550', 'G05.810.550'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830'], ['D12.776.964']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Event-related cortical dynamics of soldiers during shooting as a function of varied task demand. | INTRODUCTION: Cortical dynamics of soldiers were examined during a reactive shooting task under varied task demands to investigate the effects of cognitive load on functional states of soldiers in real-time.METHODS: Task demand factors consisted of task load (single, dual), decision load (no-decision, choice-decision),... | ['Adult', 'Analysis of Variance', 'Cerebral Cortex', 'Cognition', 'Computer Simulation', 'Decision Making', 'Electroencephalography', 'Firearms', 'Humans', 'Male', 'Military Personnel', 'Psychomotor Performance', 'Reaction Time', 'Task Performance and Analysis'] | 17,547,316 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A08.186.211.200.885.287.500'], ['F02.463.188'], ['L01.224.160'], ['F02.463.785.373'], ['E01.370.376.300', 'E01.370.405.245'], ['J01.637.870.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['F02.808', 'G11.427... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Posttransplantation lymphoproliferative disorder: manifestations in pediatric thoracic organ recipients. | PURPOSE: To describe and correlate the clinical and imaging features of posttransplantation lymphoproliferative disorder (PTLD) in young thoracic organ transplant recipients.MATERIALS AND METHODS: The authors retrospectively reviewed the medical and imaging records of 31 PTLD episodes in 27 patients with PTLD out of 18... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Heart Transplantation', 'Heart-Lung Transplantation', 'Humans', 'Infant', 'Lung Transplantation', 'Lymphoproliferative Disorders', 'Male', 'Radiography, Abdominal', 'Radiography, Thoracic', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 11,867,788 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.100.376.475.450', 'E04.928.220.390.450', 'E04.928.600.495.450', 'E04.936.450.475.450', 'E04.936.450.495.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E04... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gesture helps learners learn, but not merely by guiding their visual attention. | Teaching a new concept through gestures-hand movements that accompany speech-facilitates learning above-and-beyond instruction through speech alone (e.g., Singer & Goldin-Meadow, ). However, the mechanisms underlying this phenomenon are still under investigation. Here, we use eye tracking to explore one often proposed ... | ['Attention', 'Child', 'Gestures', 'Humans', 'Learning', 'Mathematics', 'Speech', 'Vision, Ocular'] | 29,663,574 | [['F02.830.104.214'], ['M01.060.406'], ['F01.145.209.530.538.445'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['H01.548'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
[A slowly progressed case of brain metastasis and meningeal carcinomatosis from lung cancer]. | We reported a case of long survival brain metastasis and meningeal carcinomatosis from lung cancer without radiochemotherapy. A 59-year-old female admitted to our hospital suffered from headache, anorexia and nausea. Papilledema was noticed, and examinations showed a brain tumor in the left parietal lobe and cancer cel... | ['Adenocarcinoma', 'Brain Neoplasms', 'Disease Progression', 'Female', 'Humans', 'Lung Neoplasms', 'Meningitis', 'Middle Aged'] | 9,430,151 | [['C04.557.470.200.025'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C10.228.614'], ['M01.060.116.630']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Wetland management to reduce Baltic Sea eutrophication. | Seven regions with coastal eutrophication problems in the Baltic Sea, including the Kattegat, constitute the BERNET project (Baltic Eutrophication Regional Network). To counteract eutrophication and associated severe biological conditions the countries around this large brackish water body must all cooperate. The regio... | ['Agriculture', 'Baltic States', 'Conservation of Natural Resources', 'Ecosystem', 'Eutrophication', 'Filtration', 'International Cooperation', 'Nitrogen', 'Water Movements', 'Water Pollution'] | 12,079,128 | [['J01.040'], ['Z01.542.248.136'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.285'], ['E05.196.454', 'G01.280', 'G02.263'], ['I01.615.500'], ['D01.268.604', 'D01.362.625'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850'], ['N06.850.460.790']] | ['Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Identification of a haem domain in human soluble adenylate cyclase. | The second messengers cAMP and cGMP mediate a multitude of physiological processes. In mammals, these cyclic nucleotides are formed by related Class III nucleotidyl cyclases, and both ACs (adenylate cyclases) and GCs (guanylate cyclases) comprise transmembrane receptors as well as soluble isoforms. Whereas sGC (soluble... | ['Adenylyl Cyclases', 'Animals', 'Binding Sites', 'Carbon Monoxide', 'Catalytic Domain', 'Cyclic AMP', 'Heme', 'Humans', 'Iron', 'Male', 'Mice', 'Muscle, Skeletal', 'Nitric Oxide', 'Protein Structure, Tertiary', 'Testis'] | 22,775,536 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['G02.111.570.120'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.383.129... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CyberKnife radiosurgery for trigeminal neuralgia: unanticipated iatrogenic effect following successful treatment. | This case report of 74-year-old man with trigeminal neuralgia is presented to underscore the importance of evaluating the entire treatment plan, especially when delivering large doses where even a low percentage of the prescription dose can contribute a substantial dose to an unintended target. The patient was treated ... | ['Aged', 'Humans', 'Male', 'Radiosurgery', 'Stomatitis', 'Treatment Outcome', 'Trigeminal Neuralgia'] | 21,761,970 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['C07.465.864'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C07.465.299.625.500.700', 'C10.292.319.625.700.700']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of aromatherapy massage on face-down posture-related pain after vitrectomy: a randomized controlled trial. | Postoperative face-down posturing (FDP) is recommended to optimize the effects of intraocular gas tamponade after vitrectomy. However, patients undergoing FDP usually experience physical and psychological burdens. This 3-armed, randomized, single-center trial investigated the effects of aromatherapy on FDP-related phys... | ['Aged', 'Aromatherapy', 'Female', 'Humans', 'Male', 'Massage', 'Middle Aged', 'Oils', 'Pain Management', 'Pain, Postoperative', 'Prone Position', 'Treatment Outcome', 'Vitrectomy'] | 23,466,193 | [['M01.060.116.100'], ['E02.190.525.061', 'E02.190.755.100', 'E02.190.888.061', 'F04.754.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.599.750.750', 'E02.779.867.880.750', 'E02.831.535.867.880.750'], ['M01.060.116.630'], ['D10.627'], ['E02.745', 'N04.590.607.500'], ['C23.550.767.700', 'C23.888.592.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Fatal hydrogen sulphide (H2S) poisoning in "confined spaces"]. | This paper deals with the problem of fatal accidents that occur repeatedly in "confined spaces", with particular attention to exposure to hydrogen sulfide (H2S). This, at high concentrations, appears to be the most compatible with the dynamics of many recent incidents with sudden death. H2S offers little chance to esca... | ['Accidents, Occupational', 'Air Pollution, Indoor', 'Humans', 'Hydrogen Sulfide'] | 23,393,847 | [['N06.850.135.240'], ['N06.850.460.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.340', 'D01.362.350', 'D01.875.350']] | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Absorption, Metabolism, and Pharmacokinetics Profiles of Norathyriol, an Aglycone of Mangiferin, in Rats by HPLC-MS/MS. | Norathyriol, an aglycone of mangiferin, is a bioactive tetrahydroxyxanthone present in mangosteen and many medicinal plants. However, the biological fate of norathyriol in vivo remains unclear. In this study, the absorption and metabolism of norathyriol in rats were evaluated through HPLC-MS/MS. Results showed that nor... | ['Animals', 'Chromatography, High Pressure Liquid', 'Hepatocytes', 'Male', 'Rats', 'Rats, Wistar', 'Tandem Mass Spectrometry', 'Xanthenes', 'Xanthones'] | 30,298,742 | [['B01.050'], ['E05.196.181.400.300'], ['A11.436.348'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['E05.196.566.880'], ['D03.633.300.953'], ['D03.633.300.953.852']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Repair of the diaphragm with an external oblique muscle flap. | The technique for repair of large defects in the diaphragm by the use of an ipsilateral or contralateral flap from the external oblique abdominal muscle was successfully used during five hepatic resections and has been described herein. | ['Aged', 'Diaphragm', 'Evaluation Studies as Topic', 'Humans', 'Methods', 'Middle Aged', 'Surgical Flaps'] | 2,756,464 | [['M01.060.116.100'], ['A02.633.567.900.300'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Computationally efficient measure of topological redundancy of biological and social networks. | It is well known that biological and social interaction networks have a varying degree of redundancy, though a consensus of the precise cause of this is so far lacking. In this paper, we introduce a topological redundancy measure for labeled directed networks that is formal, computationally efficient, and applicable to... | ['Animals', 'Computer Simulation', 'Drosophila melanogaster', 'Gene Regulatory Networks', 'Protein Interaction Maps', 'Signal Transduction', 'Social Networking', 'Software'] | 22,060,466 | [['B01.050'], ['L01.224.160'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.360.080.689.360'], ['G03.493.750'], ['G02.111.820', 'G04.835'], ['L01.143.910'], ['L01.224.900']] | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An all sulfur analogue of the smallest subunit of F420-non-reducing hydrogenase from Methanococcus voltae--metal binding and structure. | The 25 amino acid long subunit VhuU of the F420-non-reducing hydrogenase from Methanococcus voltae contains selenocysteine within the consensus sequence of known [NiFe] hydrogenases DP(C or U)CxxCxxH (U = selenocysteine). The sulfur-analogue VhuUc was chemically synthesized, purified and its metal binding capability, t... | ['Amino Acid Sequence', 'Binding Sites', 'Catalysis', 'Hydrogen', 'Hydrogenase', 'Magnetic Resonance Spectroscopy', 'Metals', 'Methanococcus', 'Molecular Sequence Data', 'Molecular Structure', 'Nickel', 'Protein Structure, Secondary', 'Selenocysteine', 'Sequence Alignment', 'Sulfur'] | 9,084,873 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['G02.130'], ['D01.268.406', 'D01.362.340'], ['D08.811.682.400'], ['E05.196.867.519'], ['D01.552'], ['B02.200.538.525.500'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['G02.111.570.820.709... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevention of cholesterol-induced gallstones by hyodeoxycholic acid in the prairie dog. | Prairie dogs of both sexes were fed a semisynthetic diet containing 0.35% cholesterol for a period of 8 weeks. This lithogenic diet induced cholesterol gallstones in ten "lithogenic control animals", five males and five females. Three animals maintained with a high glucose, fat-free diet did not develop gallstones alth... | ['Animals', 'Bile', 'Bile Acids and Salts', 'Cholelithiasis', 'Cholesterol', 'Cholesterol 7-alpha-Hydroxylase', 'Cholesterol, Dietary', 'Chromatography, Gas', 'Deoxycholic Acid', 'Feces', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Hydroxymethylglutaryl CoA Reductases', 'Lipids', 'Liver', 'Male', 'Sciuridae'] | 6,747,458 | [['B01.050'], ['A12.200.087'], ['D04.210.500.105'], ['C06.130.409'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D08.244.453.890.500', 'D08.244.453.915.200', 'D08.811.682.690.708.170.890.500', 'D08.811.682.690.708.170.915.200', 'D12.776.422.220.453.890.500', 'D12.776.422.220.453.915.200... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Papillary thyroid carcinoma from tall and columnar cells]. | The paper analyzes the data available in the literature on the morphological and prognostic features of the relatively rare morphological types of papillary thyroid carcinoma from tall and columnar cells. It is shown that the poor prognostic tall cell variant may be successfully diagnosed in the cytological smears of p... | ['Biomarkers, Tumor', 'Carcinoma', 'Carcinoma, Papillary', 'Diagnosis, Differential', 'Humans', 'Prognosis', 'Thyroid Cancer, Papillary', 'Thyroid Neoplasms'] | 21,695,993 | [['D23.101.140'], ['C04.557.470.200'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['C04.557.470.200.025.085.612', 'C04.588.322.894.400', 'C04.588.443.915.400', 'C19.344.894.400', 'C19.874.788.400'], ['C04.588.322.894', 'C04.588.443.915', 'C... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Altered Polyamine Profiles in Colorectal Cancer. | BACKGROUND: The declining mortality rate of patients with colorectal cancer (CRC) can be explained, at least partially, with early diagnosis. Simple diagnostic methods are needed to achieve a maximal patient participation rate in screening.MATERIALS AND METHODS: Liquid chromatography electrospray tandem mass spectromet... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Chromatography, Liquid', 'Colorectal Neoplasms', 'Early Diagnosis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polyamines', 'Prospective Studies', 'Sensitivity and Specificity', 'Spermine', 'Tandem Mass Spectrometry'] | 29,848,716 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['E05.196.181.400'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.092.782'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detecting differentially expressed genes in heterogeneous diseases using half Student's t-test. | BACKGROUND: Microarray technology provides information about hundreds and thousands of gene-expression data in a single experiment. To search for disease-related genes, researchers test for those genes that are differentially expressed between the case subjects and the control subjects.METHODS: The authors propose a ne... | ['Colonic Neoplasms', 'Computer Simulation', 'Gene Expression', 'Humans', 'Models, Statistical', 'Monte Carlo Method', 'Statistics, Nonparametric'] | 20,519,335 | [['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['L01.224.160'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.740.525... | ['Diseases [C]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Analysis of direct costs of controlling arterial hypertension]. | OBJECTIVE: To analyse the number of attendances and the direct cost of pharmaceutical prescription arising from a year-long monitoring of hypertense patients.SETTING: Health Centre.DESIGN: A prospective observation study.PATIENTS: 220 hypertense patients, undergoing arterial pressure (AP) monitoring, were chosen by mea... | ['Adult', 'Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Antihypertensive Agents', 'Costs and Cost Analysis', 'Diabetes Complications', 'Diuretics', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Office Visits', 'Prospective Studies'] | 7,986,982 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.389.745.085'], ['D27.505.954.411.162'], ['N03.219.151'], ['C19.246.099'], ['D27.505.696.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['N04.452.758.635'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sharing a Personal Trainer: Personal and Social Benefits of Individualized, Small-Group Training. | Wayment, HA and McDonald, RL. Sharing a personal trainer: personal and social benefits of individualized, small-group training. J Strength Cond Res 31(11): 3137-3145, 2017-We examined a novel personal fitness training program that combines personal training principles in a small-group training environment. In a typical... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Exercise', 'Female', 'Group Processes', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Motivation', 'Personal Autonomy', 'Personal Satisfaction', 'Self Efficacy', 'Social Support', 'Surveys and Questionnaires', 'Young Adult'] | 28,353,489 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.410.698.277', 'I03.350'], ['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['F02.600', 'I01.880.604.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Fatal peripheral neuropathy with predominant motor involvement associated with anti-MAG IgM monoclonal gammapathy]. | A 75 year old woman died of predominantly motor peripheral neuropathy with amyotrophy and fasciculations progressing to tetraplegia and death within 19 months. There was a mild distal sensory loss. At electrophysiology, the pattern was initially demyelinating and later became axonal. Nerve biopsy disclosed severe myeli... | ['Aged', 'Demyelinating Diseases', 'Fatal Outcome', 'Female', 'Humans', 'Hypergammaglobulinemia', 'Immunoglobulin M', 'Immunoglobulin kappa-Chains', 'Myelin Proteins', 'Myelin Sheath', 'Myelin-Associated Glycoprotein', 'Peripheral Nervous System Diseases', 'Quadriplegia'] | 7,516,570 | [['M01.060.116.100'], ['C10.314'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.147.542', 'C20.683.460', 'C23.888.512'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fine-resolution mapping of particulate matter concentration in urban areas and population exposure analysis via dispersion modeling: a study in Daejeon, South Korea. | To deliver accurate particulate matter information to citizens, a detailed particulate matter dispersion model including factors such as land use and meteorological information was developed and used to create particulate matter concentration distribution maps for Daejeon Metropolitan City (South Korea). The results sh... | ['Air Pollutants', 'Cities', 'Environmental Exposure', 'Environmental Monitoring', 'Humans', 'Meteorological Concepts', 'Models, Theoretical', 'Particulate Matter', 'Republic of Korea', 'Urban Population'] | 30,955,199 | [['D27.888.284.101'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.750', 'N06.230.300'], ['E05.599'], ['D20.633'], ['Z01.252.474.557.750'], ['N01.600.900']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The SJL/J mouse: a new model for spontaneous age-associated amyloidosis. I. Morphologic and immunochemical aspects. | A high incidence of spontaneous amyloidosis is described in SJL/J mice. Amyloid was detected as early as 30 weeks of age and the incidence rose to 90 per cent by 60 weeks of age. Amyloid deposits were most prominent in the perifollicular zones of the spleen and the lobular areas of the liver. Ultrastructural analysis r... | ['Age Factors', 'Amino Acid Sequence', 'Amyloid', 'Amyloidosis', 'Animals', 'Caseins', 'Disease Models, Animal', 'Female', 'Kidney', 'Lymphoma, Large B-Cell, Diffuse', 'Mice', 'Mice, Inbred Strains', 'Microscopy, Electron', 'Molecular Weight', 'Sarcoma, Experimental', 'Spleen'] | 781,403 | [['N05.715.350.075', 'N06.850.490.250'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D05.500.049', 'D12.776.049'], ['C18.452.845.500'], ['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A05.810.453'], ['C04.557.386.480.150.585', 'C15.604.515.569.480.150.585'... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Aqueous chromatographic system for separation of biomolecules using thermoresponsive polymer modified stationary phase. | We have investigated a new method for HPLC using packing materials modified with a functional polymer, such as thermoresponsive poly(N-isopropylacrylamide) (PNIPAAm). PNIPAAm-modified silica exhibits temperature-controlled hydrophilic-hydrophobic surface property changes in aqueous systems. Temperature-responsive chrom... | ['Acrylamides', 'Acrylic Resins', 'Chromatography, High Pressure Liquid', 'Humans', 'Muramidase', 'Polymers', 'Proteins', 'Serum Albumin', 'Temperature'] | 18,289,554 | [['D02.065.122', 'D02.241.081.069.094'], ['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.450.642'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D12.776'], ['D12.776.034.841', 'D12.776.124.727'], ['G01... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Continuation phase intravenous ketamine in adults with treatment-resistant depression. | BACKGROUND: Little is known about the antidepressive effects of repeated intravenous ketamine infusions beyond the acute phase of treatment in patients with refractory depression.METHODS: Twelve subjects with treatment-resistant non-psychotic unipolar or bipolar major depression and suicidal ideation were given repeate... | ['Adult', 'Antidepressive Agents', 'Bipolar Disorder', 'Depressive Disorder, Major', 'Depressive Disorder, Treatment-Resistant', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Infusions, Intravenous', 'Ketamine', 'Male', 'Middle Aged', 'Remission Induction', 'Sample Size', 'Suicidal Ideation', 'Young Adult'] | 27,656,788 | [['M01.060.116'], ['D27.505.954.427.700.122'], ['F03.084.500'], ['F03.600.300.375'], ['F03.600.300.388'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['D02.455.426.392.368.367.652'], ['M01.060.116.630'], ['E02.860'], ['E05.318.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The management of unstable oblique infected mandibular fractures with a 2.3 mm mandibular osteosynthesis reconstruction bone plate. | UNLABELLED: This study is aimed to evaluate the efficacy of 2.3mm reconstruction bone plates in the treatment of unstable infected mandibular fractures.MATERIAL: The study included 32 patients with unstable oblique infected mandibular fractures (23 males and 9 females), with a mean age of 33 years. The patients were di... | ['Adult', 'Biocompatible Materials', 'Bone Plates', 'Bone Screws', 'Equipment Design', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Humans', 'Hypesthesia', 'Jaw Fixation Techniques', 'Male', 'Mandibular Fractures', 'Middle Aged', 'Osteogenesis', 'Postoperative Complications', 'Reconstructive Surgical ... | 21,334,216 | [['M01.060.116'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E05.320'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Characterization of commercial slovenian and cypriot fruit juices using stable isotopes. | The compositions of commercially available fruit juices on the Slovenian and Cypriot markets have been compared and checked against the corresponding declarations on the packaging. Values of delta(13)C in the pulp, sugars, and ethanol (produced by fermentation and distillation) have been obtained by isotope ratio mass ... | ['Beverages', 'Carbon Isotopes', 'Cyprus', 'Fruit', 'Isotope Labeling', 'Mass Spectrometry', 'Oxygen Isotopes', 'Slovenia'] | 19,586,026 | [['G07.203.100', 'J02.200'], ['D01.268.150.075', 'D01.496.123'], ['Z01.542.580.500.300', 'Z01.639.640.300'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.522'], ['E05.196.566'], ['D01.268.185.550.500', 'D01.362.670.300', 'D01.496.625'], ['Z01.542.248.820']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Absorption profiling of cyclosporine microemulsion (neoral) during the first 2 weeks after renal transplantation. | BACKGROUND: Evidence suggests that optimal immunosuppressive drug exposure must be achieved early posttransplant to minimize the risk of acute graft rejection. This study was designed to examine the absorption profile of Neoral during the first 2 weeks after renal transplantation, to develop simple sparse-sampling phar... | ['Absorption', 'Acute Disease', 'Adult', 'Cyclosporine', 'Dose-Response Relationship, Drug', 'Emulsions', 'Female', 'Graft Rejection', 'Humans', 'Immunosuppressive Agents', 'Incidence', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Period', 'Prospective Studies', 'Time Factors'] | 11,579,295 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['C23.550.291.125'], ['M01.060.116'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G07.690.773.875', 'G07.690.936.500'], ['D20.280.260', 'D26.255.165.260'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Distribution of plasma total homocysteine concentrations in the healthy Iranians. | OBJECTIVE: The distribution of plasma total homocysteine concentrations in a population of South West of Iran Shiraz is described to test for differences in homocysteine concentrations among gender and age groups and those levels reported in other populations.DESIGN AND METHODS: Two hundred one healthy males and 201 he... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Cardiovascular Diseases', 'Female', 'Homocysteine', 'Humans', 'Iran', 'Male', 'Middle Aged', 'Risk Factors', 'Sex Factors'] | 14,725,947 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C14'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700'... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Survival of Children With Hypoplastic Left Heart Syndrome. | OBJECTIVE: To examine the survival of infants with hypoplastic left heart syndrome (HLHS) and potential influence of demographic and clinical characteristics on survival using population-based data.METHODS: Infants with nonsyndromic HLHS (n = 212) born between 1979 and 2005 were identified through the Metropolitan Atla... | ['Child', 'Female', 'Follow-Up Studies', 'Georgia', 'Humans', 'Hypoplastic Left Heart Syndrome', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Probability', 'Prognosis', 'Risk Factors', 'Survival Analysis'] | 26,391,936 | [['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.240.400.625', 'C14.280.400.625', 'C16.131.240.400.625'], ['M01.060.703'], ['M01.060.703.520'], ['M01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Octadecabacter jejudonensis sp. nov., isolated from the junction between the ocean and a freshwater spring and emended description of the genus Octadecabacter. | A Gram-stain-negative, non-spore-forming, non-flagellated, rod-shaped bacterial strain, SSK2-1(T), was isolated from the zone where the ocean and a freshwater spring meet at Jeju island, South Korea, and subjected to a polyphasic taxonomic study. Strain SSK2-1(T) grew optimally at 30 °C, at pH 7.0-8.0 and in the presen... | ['Bacterial Typing Techniques', 'Base Composition', 'DNA, Bacterial', 'Fatty Acids', 'Fresh Water', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Republic of Korea', 'Rhodobacteraceae', 'Seawater', 'Sequence Analysis, DNA', 'Ubiquinone', 'Water Microbiology'] | 24,174,219 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['D13.444.308.212'], ['D10.251'], ['G16.500.275.280', 'N06.230.232'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['Z01.252.474.557.750'], ['B03.660.050.750'], ['G16.500.275.725.500'], ['E05.393.760.700'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Lipid transport and human brain development. | How the human brain rapidly builds up its lipid content during brain growth and maintains its lipids in adulthood has remained elusive. Two new studies show that inactivating mutations in MFSD2A, known to be expressed specifically at the blood-brain barrier, lead to microcephaly, thereby offering a simple and surprisin... | ['Biological Transport', 'Brain', 'Humans', 'Lipid Metabolism', 'Microcephaly', 'Symporters', 'Tumor Suppressor Proteins'] | 26,111,510 | [['G03.143'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['C05.660.207.620', 'C10.500.507.400.500', 'C16.131.621.207.620', 'C16.131.666.507.400.500'], ['D12.776.157.530.450.625', 'D12.776.543.585.450.625'], ['D12.776.624.776']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of a Shack-Hartmann aberrometer to assess the optical outcome of corneal transplantation in a keratoconic eye. | We report the optical outcome of corneal transplantation treatment on a keratoconic eye as measured with a Shack-Hartmann aberrometer, and we compare the results with the recovery of visual acuity after surgery. Before surgery, the naked keratoconic eye exhibited extremely large aberrations that could not be measured u... | ['Cornea', 'Corneal Topography', 'Humans', 'Keratoconus', 'Keratoplasty, Penetrating', 'Male', 'Middle Aged', 'Treatment Outcome', 'Visual Acuity'] | 11,780,663 | [['A09.371.060.217'], ['E01.370.380.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.204.627'], ['E02.095.147.725.225.350', 'E04.540.825.374.350', 'E04.936.580.225.350'], ['M01.060.116.630'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['E01.370.380.850.950', 'F02.463.593.932.901', '... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reversal of ischemic damage with secondary blood cardioplegia. | After severe ischemic injury, it is usually necessary to prolong bypass to enhance recovery. This study tests the hypothesis that the best reversal of ischemic damage is achieved by briefly rearresting the postischemic heart with a continuous infusion of an oxygenated cardioplegic solution (secondary blood cardioplegia... | ['Animals', 'Blood', 'Cardiopulmonary Bypass', 'Coronary Circulation', 'Coronary Disease', 'Dogs', 'Heart Arrest, Induced', 'Heart Rate', 'Myocardial Contraction', 'Myocardium', 'Oxygen Consumption', 'Stroke Volume', 'Time Factors'] | 491,722 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The exon-junction complex proteins, Y14 and MAGOH regulate STAT3 activation. | Signal transducer and activator of transcription 3 (STAT3), which is activated by cytokines and growth factors, mediates biological actions in many physiological processes. In a previous study, we found that Y14, a core component of the exon-junction complex (EJC) bound to STAT3 and upregulated the transcriptional acti... | ['Exons', 'Humans', 'Nuclear Proteins', 'Protein Binding', 'RNA, Small Interfering', 'RNA-Binding Proteins', 'STAT3 Transcription Factor', 'Transcriptional Activation'] | 19,254,694 | [['G05.360.340.024.340.137.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['G02.111.679', 'G03.808'], ['D13.150.650.700', 'D13.444.735.150.700', 'D13.444.735.790.552.875'], ['D12.776.157.725', 'D12.776.664.962'], ['D12.644.360.024.342.300', 'D12.776.157.057.186.300', 'D12.776.476.024.430.300',... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of time-of-flight and point spread function modeling on 82 | BACKGROUND: The effect of time-of-flight (TOF) and point spread function (PSF) modeling in image reconstruction has not been well studied for cardiac PET. This study assesses their separate and combined influence on 82Rb myocardial perfusion imaging in obese patients.METHODS: Thirty-six obese patients underwent rest-st... | ['Adult', 'Aged', 'Body Mass Index', 'Female', 'Heart Ventricles', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Middle Aged', 'Myocardial Perfusion Imaging', 'Obesity', 'Positron-Emission Tomography', 'Rubidium Radioisotopes', 'Sex Characteristics'] | 29,907,933 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['M01.060.116.630'], ['E01.370.350.130.875', 'E01.370.350.710.600.500', 'E01.370.370.380.500', 'E01.370.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Involvement of the FoxO3a pathway in the ischemia/reperfusion injury of cardiac microvascular endothelial cells. | FoxO3a, a member of the forkhead transcription factors, has been demonstrated to be involved in myocardial ischemia/reperfusion (I/R) injury. Cardiac microvascular endothelial cells (CMECs) are some of the predominant cells damaged immediately after myocardial I/R injury. Despite the importance of injured CMECs in an i... | ['Animals', 'Apoptosis', 'Blotting, Western', 'Cells, Cultured', 'Disease Models, Animal', 'Endothelial Cells', 'Flow Cytometry', 'Forkhead Box Protein O3', 'Forkhead Transcription Factors', 'Myocardial Reperfusion Injury', 'Rats', 'Reverse Transcriptase Polymerase Chain Reaction', 'Signal Transduction'] | 23,948,278 | [['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.436.275'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A critical role of CaBP4 in the cone synapse. | PURPOSE: CaBP4, a photoreceptor-specific protein of the rods and cones, is essential for the development and maintenance of the mouse photoreceptor synapse. In this study, double CaBP4/rod alpha-transducin knockout (Cabp4(-/-)Gnat1(-/-)) mice lacking the rod-mediated component of electrophysiologic responses were gener... | ['Animals', 'Calcium-Binding Proteins', 'Electroretinography', 'Eye Proteins', 'Fluorescent Antibody Technique, Indirect', 'Genotype', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nerve Tissue Proteins', 'Photic Stimulation', 'Retinal Cone Photoreceptor Cells', 'Retinal Rod Photoreceptor Cell... | 16,249,514 | [['B01.050'], ['D12.776.157.125'], ['E01.370.380.225', 'E01.370.405.270'], ['D12.776.306'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.375.310'], ['G05.380'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of zinc absorption by iron depends on their ratio. | Previous studies upon zinc-iron interactions gave conflicting results that could come from differences in protocol design or in trace element status of subjects. The present work assessed the influence of zinc : iron ratio and iron deficiency upon zinc absorption. The digestive absorption of zinc sulphate (100 micromol... | ['Animals', 'Cations', 'Cell Membrane', 'Disease Models, Animal', 'Female', 'Iron', 'Rats', 'Rats, Sprague-Dawley', 'Zinc'] | 11,846,013 | [['B01.050'], ['D01.248.497.300'], ['A11.284.149'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN | Lenalidomide mediates the ubiquitination and degradation of Ikaros family zinc finger protein 1 (IKZF1), IKZF3, and casein kinase 1á (CK1á) by facilitating their interaction with cereblon (CRBN), the substrate receptor for the CRL4CRBN E3 ubiquitin ligase. Through this mechanism, lenalidomide is a clinically effective ... | ['Antineoplastic Agents', 'CRISPR-Cas Systems', 'Cell Line, Tumor', 'Drug Resistance, Neoplasm', 'Humans', 'Lenalidomide', 'Multiple Myeloma', 'Ubiquitin-Conjugating Enzymes', 'Ubiquitin-Protein Ligases', 'Ubiquitination'] | 30,042,095 | [['D27.505.954.248'], ['G05.308.203.374.394'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.805.810.400', 'D03.383.621.808.519', 'D03.633.100.513.750.563'], ['C04.557.595.500', 'C14.907.454.460', 'C15.378.147.780.650', 'C15.378.463.515.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk factors associated with abscess formation among patient with leg erysipelas (cellulitis) in sub-Saharan Africa: a multicenter study. | BACKGROUND: Abscess formation is a frequent local complication of leg erysipelas. In this study we aimed at identifying factors associated with abscess formation of leg erysipelas in patients in sub-Saharan African countries.METHOD: This is a multicenter prospective study conducted in dermatology units in eight sub-Sah... | ['Abscess', 'Adolescent', 'Adult', 'Africa South of the Sahara', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Erysipelas', 'Female', 'Humans', 'Leg', 'Leg Dermatoses', 'Male', 'Middle Aged', 'Prospective Studies', 'Risk Factors', 'Time-to-Treatment', 'Tobacco Use Disorder', 'Young Adult'] | 26,666,633 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.057'], ['M01.060.116'], ['Z01.058.290'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['C01.150.252.410.890.503', 'C01.150.252.819.260', 'C01.800.720.260', 'C17.800.838.765.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.... | ['Diseases [C]', 'Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Acute appendicitis in newborn infants]. | Twenty-two observations of acute destructive appendicitis in newborns of 4 to 28 days of age are presented. A marked necrotic component of the inflammation with perforation and partial self-amputation is noted. It is assumed that a combination of general and local factors is important in the pathogenesis of acute appen... | ['Acute Disease', 'Appendicitis', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male'] | 7,082,199 | [['C23.550.291.125'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Whooping cough vaccination: some reasons for non-completion. | The decline in the number of children nationally being vaccinated against pertussis has caused anxiety and concern, both for parents and for professional workers. Publicity by the media and professional press has added to the confusion, and has been largely held responsible for the present situation. A survey was under... | ['Child', 'Evaluation Studies as Topic', 'Family', 'Humans', 'Immunization Schedule', 'Pertussis Vaccine', 'Records', 'Socioeconomic Factors', 'United Kingdom', 'Vaccination', 'Whooping Cough'] | 6,900,639 | [['M01.060.406'], ['E05.337', 'N05.715.360.335'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.470', 'E05.478.550.545'], ['D20.215.894.135.535'], ['E05.318.308.940', 'L01.399.250.900', 'N04.452.859', 'N05.715.360.300.715', 'N06.850.520.308.940'], ['I01.880.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H. | The virion host shutoff protein (vhs) of herpes simplex virus triggers accelerated degradation of cellular and viral mRNAs while sparing other cytoplasmic RNA species. Previous work has shown that vhs forms a complex with translation initiation factor eIF4H, which displays detectable RNase activity in the absence of ot... | ['Amino Acid Sequence', 'Animals', 'Endoribonucleases', 'Eukaryotic Initiation Factors', 'Gene Expression Regulation, Viral', 'Humans', 'Molecular Sequence Data', 'Protein Biosynthesis', 'RNA, Viral', 'Rabbits', 'Reticulocytes', 'Ribonucleases', 'Ribosomes', 'Saccharomyces cerevisiae', 'Simplexvirus', 'Viral Proteins'] | 15,078,951 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.277.352.355.350', 'D08.811.277.352.700.350'], ['D12.776.835.725.868'], ['G05.308.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D13.444.735.828'], ['B01.050.150.900.649.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Skin, hair and nail changes in a case of citrullinemia with late manifestation. | We report the case of a 56-year-old woman with a history of episodes of vomiting and coma. Hyperammoniemia , hypouremia , hypercitrullinemia and the decreased arginino -succinic synthetase activity on skin fibroblast cultures permitted us to diagnose citrullinemia. We think that the skin changes, i.e. atrophy of the ep... | ['Age Factors', 'Amino Acids', 'Atrophy', 'Citrulline', 'Female', 'Humans', 'Middle Aged', 'Nail Diseases', 'Osteoarthropathy, Secondary Hypertrophic', 'Skin', 'Syndrome'] | 6,724,076 | [['N05.715.350.075', 'N06.850.490.250'], ['D12.125'], ['C23.300.070'], ['D12.125.095.226'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C17.800.529'], ['C05.116.758', 'C05.550.684'], ['A17.815'], ['C23.550.288.500']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Increased measuring rate of an in vivo phagocytosis test by using frozen samples]. | The in vivo phagocytosis test, as described by Dunn et al., allows only a limited number of measurements because the preparations do not last long. That's why it was tested, whether deepfreezing allows the evaluation of the preparations at a later time. The results show, that there were no differences between the count... | ['Animals', 'Escherichia coli', 'Freezing', 'Macrophages', 'Mengovirus', 'Mice', 'Mice, Inbred Strains', 'Phagocytosis'] | 2,840,814 | [['B01.050'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B04.820.578.750.170.200.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased activation of the transcription factor c-Jun by MAP kinases in monocytes of multiple trauma patients is associated with adverse outcome and mass transfusion. | BACKGROUND: Post-traumatic dysfunction of the immune system is a major source of morbidity and mortality in patients with multiple trauma. The underlying intracellular mechanisms are still incompletely understood. Previous mRNA expression studies in monocytes suggested an involvement of the MAP kinases p38 and JNK and ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Blood Transfusion', 'Female', 'Humans', 'JNK Mitogen-Activated Protein Kinases', 'MAP Kinase Signaling System', 'Male', 'Middle Aged', 'Monocytes', 'Multiple Trauma', 'Phosphoproteins', 'Proto-Oncogene Proteins c-jun', 'Treatment Outcome', 'Young Adult', 'p38 Mitoge... | 22,677,613 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.095.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.567.374', 'D12.644.360.450.340', 'D12.776.476.450.340'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['M01.060.116.630'], ['A11.118.637.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rapid removal of vancomycin by continuous veno-venous hemofiltration. | We describe a 14-year-old girl with staphylococcal (coagulase-negative) ventriculo-peritoneal shunt infection, who developed oliguric acute renal failure and was found to have a serum vancomycin concentration of 250 microg/ml. Since only about 10%-50% of vancomycin is bound to protein in blood, we employed continuous v... | ['Acute Kidney Injury', 'Adolescent', 'Anti-Bacterial Agents', 'Female', 'Hemofiltration', 'Humans', 'Staphylococcal Infections', 'Vancomycin', 'Ventriculoperitoneal Shunt'] | 10,975,298 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.057'], ['D27.505.954.122.085'], ['E02.870.225', 'E04.292.471'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.868'], ['D09.400.420.925', 'D12.644.233.925'], ['E04.035.188.850', 'E04.525.170.850']] | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Automated assignment of SCOP and CATH protein structure classifications from FSSP scores. | We present an automated procedure to assign CATH and SCOP classifications to proteins whose FSSP score is available. CATH classification is assigned down to the topology level, and SCOP classification is assigned to the fold level. Because the FSSP database is updated weekly, this method makes it possible to update als... | ['Algorithms', 'Amino Acid Sequence', 'Animals', 'Automation', 'Databases, Protein', 'Internet', 'Models, Molecular', 'Protein Conformation', 'Protein Folding', 'Proteins', 'Reproducibility of Results', 'Sequence Alignment'] | 11,835,515 | [['G17.035', 'L01.224.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['J01.897.104'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['L01.224.230.110.500'], ['E05.599.595'], ['G02.111.570.820.709'], ['G01.154.651', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Mesoporous Europium-Doped Titania Nanoparticles (Eu-MTNs) for Luminescence-Based Intracellular Bio-Imaging. | Monodisperse and mesoporous europium (Eu)-doped titania nanoparticles (denoted as Eu-MTNs) were prepared by a co-synthesis method with the presence of a cationic surfactant (i.e., CTAB). A maximum loading amount of 8 mol% of Eu could be successfully incorporated into the framework of MTNs. The synthesized Eu-MTNs sampl... | ['Europium', 'Luminescence', 'Luminescent Measurements', 'Microscopy, Electron, Scanning', 'Molecular Imaging', 'Nanoparticles', 'Titanium', 'X-Ray Diffraction'] | 26,682,415 | [['D01.268.558.362.468', 'D01.552.550.399.468'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E05.196.712.516'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.350.557', 'E05.601.555'], ['J01.637.512.600'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Grape seed extract enhances eNOS expression and NO production through regulating calcium-mediated AKT phosphorylation in H2O2-treated endothelium. | GSE (grape seed extract) has been shown to exhibit protective effects against cardiovascular events and atherosclerosis, although the underlying molecular mechanisms of action are unknown. Herein, we assessed the ability of GSE to enhance eNOS (endothelial nitric oxide synthase) expression and NO (nitric oxide) product... | ['Biflavonoids', 'Boron Compounds', 'Calcium', 'Catechin', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Endothelial Cells', 'Gene Expression Regulation', 'Grape Seed Extract', 'Humans', 'Hydrogen Peroxide', 'Inositol 1,4,5-Trisphosphate', 'Inositol 1,4,5-Trisphosphate Receptors', 'Nitric Oxide', 'Nitric Oxid... | 20,513,234 | [['D03.383.663.283.266.450.190', 'D03.633.100.150.266.450.190'], ['D01.132', 'D02.203'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['A11... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The independent effects of atmospheric pressure and oxygen partial pressure on gas exchange of the chicken embryo. | CO2 production and air cell PCO2 were continuously measured during late development in the chicken egg while acutely exposed from one to three hours to various O2 concentrations ranging from 11 to 39%. A small but significant increase in metabolism, ca. 8%, was found when O2 concentration was above normal values, while... | ['Animals', 'Atmospheric Pressure', 'Carbon Dioxide', 'Chick Embryo', 'Dose-Response Relationship, Drug', 'Oxygen', 'Time Factors'] | 7,361,018 | [['B01.050'], ['G16.500.750.274', 'N06.230.300.100.185'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['A13.350.150', 'A16.331.200'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.268.185.550', 'D01.362.670'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Risk of asthma exacerbation associated with nonsteroidal anti-inflammatory drugs in childhood asthma: A nationwide population-based cohort study in Taiwan. | Patients allergic to aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) who develop respiratory reactions such as bronchospasm or asthma exacerbation have aspirin-induced asthma or NSAIDs-exacerbated respiratory disease. However, large-scale studies have not been conducted to investigate the risk of aspirin/NSAID... | ['Adolescent', 'Anti-Inflammatory Agents, Non-Steroidal', 'Asthma', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Population Surveillance', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Taiwan'] | 27,741,128 | [['M01.060.057'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.90... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Identification of 2':3'-cyclic nucleotide 3'-phosphodiesterase in the vertebrate retina. | The enzyme, 2':3'-cyclic nucleotide 3'-phosphodiesterase (2':3'-cNMP-3'-ase) has been used as a marker in the nervous system for the presence of myelin membrane or myelin-producing glial cells. In this study, goldfish and bovine neural retinas are found to have high levels of such a diesterase activity. Analysis of ret... | ["2',3'-Cyclic-Nucleotide Phosphodiesterases", 'Animals', 'Cattle', 'Cyclic AMP', 'Cyprinidae', 'Goldfish', 'Hydrolysis', 'Optic Nerve', 'Phosphoric Diester Hydrolases', 'Photoreceptor Cells', 'Retina'] | 6,248,510 | [['D08.811.277.352.640.160'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.493.200.244'], ['B01.050.150.900.493.200.244.248.480'], ['G02.380'], ['A08.800.800.120.680'], ['D08.811.277.352.640'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Examining the relative activity of several dicistrovirus intergenic internal ribosome entry site elements in uninfected insect and mammalian cell lines. | Comparisons of the relative activities of 11 intergenic region (IGR) internal ribosome entry site (IRES) elements of insect dicistrovirus with 5' IRES elements of the hepatitis C and encephalomyocarditis viruses were performed in insect and mammalian cells. Dual luciferase assays were performed to determine the most ef... | ['Aedes', 'Animals', 'Bombyx', 'Cell Line', 'DNA, Intergenic', 'Drosophila melanogaster', 'Enhancer Elements, Genetic', 'Humans', 'Insect Viruses', 'Luciferases', 'Plasmids', 'RNA Splicing', 'RNA Viruses', 'RNA, Messenger', 'RNA, Viral', 'Ribosomes', 'Spodoptera'] | 19,008,405 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['A11.251.210'], ['D13.444.308.324', 'G05.360.340.024.220'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'],... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The dose distribution close to an 192Ir wire source: EGS4 Monte Carlo calculations. | A Monte Carlo simulation using the PRESTA version of the EGS4 code has been employed as an investigative tool to calculate the absorbed dose in water close to 192Ir wire implants. It has been shown that a treatment planning system, such as GE Target II, using the Sievert integral and the Meisberger polynomial is only a... | ['Brachytherapy', 'Electrons', 'Humans', 'Iridium Radioisotopes', 'Methylmethacrylate', 'Methylmethacrylates', 'Monte Carlo Method', 'Nasopharyngeal Neoplasms', 'Phantoms, Imaging', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Recurrence'] | 9,044,421 | [['E02.815.150'], ['G01.249.335', 'G01.358.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.496.749.500'], ['D02.241.081.069.800.550.450', 'D05.750.716.822.111.650.605.450', 'D25.720.716.822.111.650.605.450', 'J01.637.051.720.716.822.111.650.605.450'], ['D02.241.081.069.800.550', 'D05.750.716.822.111.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
[Proximal composition, lipid and cholesterol content of meat from pigs fed peach-palm meal (Bactris gasipaes Kunth) and synthetic lysine]. | Two experiments were conducted to evaluate the proximal composition, lipids and cholesterol content of meat from pigs fed diets with peach-palm meal (PPM), with or without addition of synthetic lysine (LYS). In experiment 1, 24 pigs were randomly allotted into six treatments with three levels of PPM (0.16 and 32%) and ... | ['Animal Feed', 'Animals', 'Arecaceae', 'Cholesterol', 'Lipids', 'Lysine', 'Meat', 'Swine'] | 22,097,296 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.650.940.800.575.912.250.093'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D10'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['G07.203.300.600', 'J02.500.600'], ['B01.050.150.900.649.313.500.880']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Longitudinal Changes in Optic Nerve Head Blood Flow in Normal Rats Evaluated by Laser Speckle Flowgraphy. | Purpose: To investigate longitudinal changes in mean blur rate (MBR) measured by laser speckle flowgraphy (LSFG) in the rat optic nerve head (ONH), and the reproducibility of MBR.Methods: Rats were dilated under general anesthesia. Intraocular pressure (IOP), blood pressure, ocular perfusion pressure (OPP), heart rate,... | ['Animals', 'Blood Pressure', 'Heart Rate', 'Laser-Doppler Flowmetry', 'Male', 'Microcirculation', 'Optic Disk', 'Rats', 'Rats, Inbred BN', 'Reference Values', 'Regional Blood Flow', 'Reproducibility of Results'] | 27,768,795 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E01.370.370.475', 'E05.830.500'], ['G09.330.100.645'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.110', 'B01.050.150.900.649.313.992.635.505... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients. | OBJECTIVE: Subjective scales to assess agitation and sedation in adult intensive care unit (ICU) patients have rarely been tested for validity or reliability. We revised and prospectively tested the Sedation-Agitation Scale (SAS) for interrater reliability and compared it with the Ramsay scale and the Harris scale to t... | ['Adult', 'Aged', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Intensive Care Units', 'Intubation', 'Male', 'Middle Aged', 'Nursing Assessment', 'Observer Variation', 'Prospective Studies', 'Psychometrics', 'Psychomotor Agitation', 'Reproducibility of Results'] | 10,446,827 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['N02.278.388.493'], ['E02.585', 'E05.497'], ['M01.060.116.630'], ['N04.590.233.508.480'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E05.3... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Consolidation anti-CD22 fractionated radioimmunotherapy with 90 | BACKGROUND: Radioimmunotherapy represents a potential option as consolidation after chemoimmunotherapy in patients with diffuse large B-cell lymphoma who are not candidates for transplantation. We aimed to assess activity and toxicity of fractionated radioimmunotherapy using anti-CD22 90Y-epratuzumab tetraxetan as cons... | ['Aged', 'Antibodies, Monoclonal, Humanized', 'Antibodies, Monoclonal, Murine-Derived', 'Antineoplastic Agents, Immunological', 'Antineoplastic Combined Chemotherapy Protocols', 'Cyclophosphamide', 'Doxorubicin', 'Female', 'Humans', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'Middle Aged', 'Prednisone', 'Prospective St... | 27,964,867 | [['M01.060.116.100'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['D27.505.954.248.384'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Protective properties of five newly synthesized cyclic compounds against sodium azide and N-methyl-N'-nitro-N-nitrosoguanidine genotoxicity. | The current study aims to determine the antimutagenic potential of five newly synthesized cyclic compounds against the genotoxic agents sodium azide (NaN₃) and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). The mutant bacterial tester strains were NaN₃-sensitive Salmonella typhimurium TA1535 and MNNG-sensitive Escherichi... | ['Analysis of Variance', 'Antimutagenic Agents', 'Escherichia coli', 'Heterocyclic Compounds', 'Methylnitronitrosoguanidine', 'Mutagenicity Tests', 'Mutagens', 'Mutation', 'Salmonella typhimurium', 'Sodium Azide'] | 21,967,842 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.706.080', 'D27.720.799.042'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D03'], ['D02.078.370.649.400', 'D02.654.567.400'], ['E05.393.560', 'E05.940.560'], ['D27.888.569.468'], ['G05.365.590'], ['B03.440.450.425.800.200.825... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Vulvar pythiosis in two captive camels (Camelus dromedarius). | Two camels (Camelus dromedarius), 3- and 4-years-old, respectively, from an eastern Tennessee wildlife farm presented with persistent weight loss and large vulvar masses. An initial biopsy of the vulvar mass of one of the camels performed by a local veterinarian showed eosinophilic dermatitis. An allergic or parasitic ... | ['Animals', 'Camelus', 'Female', 'Histocytochemistry', 'Pythiosis', 'Pythium', 'Tennessee', 'Vulvar Diseases'] | 21,696,258 | [['B01.050'], ['B01.050.150.900.649.313.500.190.180'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['C01.610.701.844', 'C22.761'], ['B01.750.580.750'], ['Z01.107.567.875.075.775'], ['C13.351.500.944']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
[In vitro differentiation of rat bone mesenchymal stem cells into neuron-like cells induced by vitamin A acid etc]. | OBJECTIVE: To explore the feasibility of inducing rat bone mesenchymal stem cells (BMSC) to differentiate into neuron-like cells with the use of Vitamin A acid, zinc and rat injured spinal cord extracts in vitro.METHODS: The BMSC were isolated from rat, cultured for 4 passages, and were treated with 10 ng/ml basic fibr... | ['Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Division', 'Cells, Cultured', 'Glial Fibrillary Acidic Protein', 'Neurofilament Proteins', 'Neurons', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord Injuries', 'Stem Cells', 'Tretinoin', 'Zinc'] | 12,910,667 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['D05.750.078.593.630', 'D12.776.220.475.630', 'D12.776.631.630'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development and evaluation of a novel MR-compatible pelvic end-to-end phantom. | MR-only treatment planning and MR-IGRT leverage MRI's powerful soft tissue contrast for high-precision radiation therapy. However, anthropomorphic MR-compatible phantoms are currently limited. This work describes the development and evaluation of a custom-designed, modular, pelvic end-to-end (PETE) MR-compatible phanto... | ['Humans', 'Magnetic Resonance Imaging', 'Male', 'Organs at Risk', 'Particle Accelerators', 'Pelvis', 'Phantoms, Imaging', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Intensity-Modulated', 'Retrospective Studies'] | 30,411,477 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A01.635'], ['E07.710.680'], ['A01.923.600'], ['E07.671'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E02.815.635.700.700', 'L01.313.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Biosolids recycling impact on biofilm extracellular enzyme activity and performance of hybrid rotating biological reactors. | Biological processes for wastewater treatment is limited by extracellular enzyme activity (EEA) of the biofilm on polymeric substrates. The efficiency of biodegradation / biosorption mechanisms causing EEA and organic load removal in biofilms remains unknown. Our hypothesis was that the limiting step of biological proc... | ['Biofilms', 'Bioreactors', 'Biosolids', 'Nitrogen', 'Sewage', 'Waste Disposal, Fluid'] | 31,846,875 | [['A20.593', 'G06.120'], ['E07.115', 'J01.897.120.115'], ['D20.944.730.500'], ['D01.268.604', 'D01.362.625'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Sensitive chiral high-performance liquid chromatographic assay for labetalol in biological fluids. | The four stereoisomers of the combined alpha- and beta-adrenoceptor antagonist labetalol were separated and quantified at therapeutic concentrations by normal-phase high-pressure liquid chromatography using a chiral stationary phase and fluorescence detection. Drug in plasma or urine was recovered by solid-phase extrac... | ['Adrenergic beta-Antagonists', 'Adult', 'Body Fluids', 'Chromatography, High Pressure Liquid', 'Humans', 'Kinetics', 'Labetalol', 'Male', 'Microchemistry', 'Stereoisomerism'] | 9,518,153 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['A12.207'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D02.033.100.291.460', 'D02.065.793.324', 'D02.092.063.291.460'], ['E05.196.620', 'H01.181.650'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Limited synergy of obesity and hypertension, prevalent risk factors in onset and progression of heart failure with preserved ejection fraction. | Obesity and hypertension are prevalent comorbidities in heart failure with preserved ejection fraction. To clarify if and how interaction between these comorbidities contributes to development of diastolic dysfunction, lean and obese ZSF1 rats were treated with deoxycorticosterone acetate implants and a high-salt diet ... | ['Animals', 'Apoptosis', 'Capillaries', 'Desoxycorticosterone Acetate', 'Disease Progression', 'Fatty Acids', 'Fibrosis', 'Gene Expression Regulation', 'Heart Failure', 'Hypertension', 'Male', 'Mitochondria', 'Myocytes, Cardiac', 'Obesity', 'Oxidative Phosphorylation', 'Oxidative Stress', 'RNA-Seq', 'Rats', 'Receptors,... | 31,368,189 | [['B01.050'], ['G04.146.954.035'], ['A07.015.461.165'], ['D04.210.500.745.745.654.339.700', 'D06.472.040.585.611.700'], ['C23.550.291.656'], ['D10.251'], ['C23.550.355'], ['G05.308'], ['C14.280.434'], ['C14.907.489'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.62... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Field-Applicable Recombinase Polymerase Amplification Assay for Rapid Detection of Mycoplasma capricolum subsp. capripneumoniae. | Contagious caprine pleuropneumonia (CCPP) is a highly contagious disease caused by Mycoplasma capricolum subsp. capripneumoniae that affects goats in Africa and Asia. Current available methods for the diagnosis of Mycoplasma infection, including cultivation, serological assays, and PCR, are time-consuming and require f... | ['Animals', 'Goats', 'Molecular Diagnostic Techniques', 'Mycoplasma capricolum', 'Nucleic Acid Amplification Techniques', 'Pleuropneumonia, Contagious', 'Sensitivity and Specificity', 'Time Factors', 'Veterinary Medicine'] | 26,085,615 | [['B01.050'], ['B01.050.150.900.649.313.500.380.513'], ['E01.370.225.880', 'E05.200.880', 'E05.393.520'], ['B03.440.860.580.553.553.210'], ['E05.393.620'], ['C01.150.252.400.610.610.717', 'C22.717'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Fitz-Hugh-Curtis Syndrome: single centre experiences. | This study was conducted to report 10 cases of Fitz-Hugh-Curtis Syndrome (FHCS) diagnosed with CT and 101 cases of FHCS-like lesion that suggested perihepatitis during laparoscopic surgery. We reviewed retrospectively the images of 3,674 laparoscopies for obstetrical and gynaecological diseases and analysed 10 cases of... | ['Adult', 'Female', 'Hepatitis', 'Humans', 'Laparoscopy', 'Pelvic Inflammatory Disease', 'Syndrome', 'Tomography, X-Ray Computed', 'Young Adult'] | 20,373,931 | [['M01.060.116'], ['C06.552.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C01.635.500', 'C13.351.500.056.750'], ['C23.550.288.500'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alpha- and beta-keratins of the snake epidermis. | Snake scales contain specialized hard keratins (beta-keratins) and alpha- or cyto-keratins in their epidermis. The number, isoelectric point, and the evolution of these proteins in snakes and their similarity with those of other vertebrates are not known. In the present study, alpha- and beta-keratins of snake molts an... | ['Animals', 'Boidae', 'Colubridae', 'Epidermis', 'Keratins'] | 17,169,542 | [['B01.050'], ['B01.050.150.900.833.672.125.500'], ['B01.050.150.900.833.672.125.750'], ['A10.272.497', 'A17.815.250'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histidine-rich glycoprotein binds fibrin(ogen) with high affinity and competes with thrombin for binding to the gamma'-chain. | Histidine-rich glycoprotein (HRG) is an abundant protein that binds fibrinogen and other plasma proteins in a Zn(2+)-dependent fashion but whose function is unclear. HRG has antimicrobial activity, and its incorporation into fibrin clots facilitates bacterial entrapment and killing and promotes inflammation. Although t... | ['Binding Sites', 'Dose-Response Relationship, Drug', 'Fibrin', 'Fibrinogen', 'Fibrinogens, Abnormal', 'Humans', 'Immunoassay', 'Immunoglobulin G', 'Kinetics', 'Ligands', 'Peptides', 'Protein Binding', 'Proteins', 'Surface Plasmon Resonance', 'Thrombin', 'Zinc'] | 21,757,718 | [['G02.111.570.120'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.124.270'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D12.776.124.050.250.265', 'D12.776.124.125.500.265', 'D23.119.490.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'],... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Authentication of Valeriana procera Kunth and comparative account of five Valeriana species. | Valeriana procera Kunth (Mexican Valerian) is a commercially important species, sometimes used as a substitute for Valeriana officinalis L., an important sedative in herbal medicine. A detailed macroscopic and microscopic account was provided for V. procera Kunth and a comparison was made between the wild and cultivate... | ['Chemistry Techniques, Analytical', 'Image Processing, Computer-Assisted', 'Microscopy', 'Plant Extracts', 'Plant Roots', 'Plants, Medicinal', 'Species Specificity', 'Starch', 'Valerian'] | 16,526,441 | [['E05.196'], ['L01.224.308'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['D20.215.784.500', 'D26.667'], ['A18.400'], ['B01.650.560'], ['G16.824'], ['D05.750.078.562.855', 'D09.301.915', 'D09.698.365.855'], ['B01.650.940.800.575.912.250.328.937.888']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Wilson's disease: a prospective study of psychopathology in 31 cases. | A prospective neuropsychiatric study of 31 consecutive subjects with Wilson's disease is reported. Exploratory factor analysis yielded four factors: neurological, cognitive, hepatic/depressive and psychiatric. Significant associations were found between a 'psychopathic' personality factor and neurological and dysarthri... | ['Adult', 'Female', 'Follow-Up Studies', 'Hepatolenticular Degeneration', 'Humans', 'Male', 'Neurocognitive Disorders', 'Neuropsychological Tests', 'Psychometrics', 'Retrospective Studies'] | 2,597,916 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C06.552.413', 'C10.228.140.079.493', 'C10.228.140.163.100.360', 'C10.228.662.400', 'C10.574.500.487', 'C16.320.400.361', 'C16.320.565.189.360', 'C16.320.565.618.403', 'C18.452.132.100.360', 'C18.452.648.189.36... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure: results from BIOSTAT-CHF. | AIMS: Association of elevated circulating levels of trimethylamine N-oxide (TMAO) with adverse outcomes in patients with heart failure (HF) has been described. However, response of TMAO levels to treatment and medications has not been investigated. Therefore, we investigated whether TMAO levels are responsive to guidel... | ['Biomarkers, Pharmacological', 'Disease Progression', 'Europe', 'Female', 'Heart Failure', 'Hospitalization', 'Humans', 'Male', 'Medication Therapy Management', 'Methylamines', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Observational Studies as Topic', 'Outcome Assessment, Health Care', 'Risk Assessment'] | 30,370,976 | [['D23.101.137'], ['C23.550.291.656'], ['Z01.542'], ['C14.280.434'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.668.438', 'N03.219.521.576.343.575.500.500', 'N03.219.521.576.343.840.938.500', 'N04.590.661'], ['D02.092.668'], ['M01.060.116.630'], ['D06.472.699.584.625'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
COSMIC(90): an improved molecular mechanics treatment of hydrocarbons and conjugated systems. | Four modifications to the COSMIC molecular mechanics force field are described, which greatly increase both its versatility and the accuracy of calculated conformational energies. The Hill non-bonded van der Waals potential function has been replaced by a two-parameter Morse curve and a new H-H potential, similar to th... | ['Computer Simulation', 'Hydrocarbons', 'Hydrogen Bonding', 'Models, Molecular', 'Molecular Conformation', 'Molecular Structure', 'Thermodynamics'] | 1,770,382 | [['L01.224.160'], ['D02.455'], ['G02.282'], ['E05.599.595'], ['G02.111.570.820'], ['G02.111.570', 'G02.466'], ['G01.906']] | ['Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Wave of free calcium at fertilization in the sea urchin egg visualized with fura-2. | A wave front of increased free calcium traversing the egg at fertilization is demonstrated in the sea urchin Lytechinus pictus. The use of the fluorescent calcium chelator fura-2 in combination with low-light-level TV microscopy and image processing allows the visualization of the Ca2+ wave front with high spatial and ... | ['Animals', 'Benzofurans', 'Calcium', 'Female', 'Fertilization', 'Fluorescent Dyes', 'Fura-2', 'Ovum', 'Sea Urchins'] | 3,365,773 | [['B01.050'], ['D03.633.100.127'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G08.686.784.277'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D03.383.129.462.285', 'D03.633.100.127.250'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['B01.050.500.408.578']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epidural sufentanil versus intramuscular buprenorphine for postoperative analgesia. A double-blind comparative trial. | Epidural sufentanil 50 micrograms was compared with intramuscular buprenorphine 0.3 mg for postoperative pain relief. Patients were assigned randomly to one of two treatment groups and received both an intramuscular and epidural injection, one of which was a placebo. Onset of pain relief was faster and quality of analg... | ['Adult', 'Analgesics, Opioid', 'Buprenorphine', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Fentanyl', 'Humans', 'Injections, Epidural', 'Injections, Intramuscular', 'Male', 'Pain, Postoperative', 'Sufentanil', 'Time Factors'] | 2,893,560 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Hydrolysis of chitosan in lactic acid]. | Effects of molecular weight and degree of acetylation on the hydrolysis of chitosan in dilute lactic acid were studied. It was demonstrated that the higher were the values of both parameters, the more rapid were the decreases in viscosity and viscosity-average molecular weight of chitosan. | ['Acetylation', 'Chitosan', 'Hydrolysis', 'Lactic Acid', 'Molecular Weight', 'Viscosity'] | 15,283,341 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D05.750.078.139.500', 'D09.698.211.500'], ['G02.380'], ['D02.241.511.459.450'], ['G02.494'], ['G02.930']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The interaction of nitric oxide and prostaglandins in the control of corporal smooth muscle tone: evidence for production of a cyclooxygenase-derived endothelium-contracting factor. | OBJECTIVE: To investigate the interaction of endothelium-derived nitric oxide (NO) and prostaglandins (PGs) in regulating corporal smooth muscle tone in vitro. Materials and methods Strips of rabbit corpus cavernosum were mounted in organ chambers for the measurement of isometric tension. Strips were submaximally contr... | ['Acetylcholine', 'Animals', 'Bridged Bicyclo Compounds, Heterocyclic', 'Cyclooxygenase Inhibitors', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Enzyme Inhibitors', 'Fatty Acids, Unsaturated', 'Hydrazines', 'In Vitro Techniques', 'Indomethacin', 'Isometric Contraction', 'Male', 'Muscle, Smooth', 'Nitric O... | 11,412,231 | [['D02.092.211.111'], ['B01.050'], ['D03.605.084'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.030.500'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['D27.505.519.389'], ['D10.251.355'], ['D02.442'], ['E05.481'], ['D03.633.100.473.420'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of sequential twin screw extrusion and fungal pretreatment to release soluble nutrients from soybean residue for carotenoid production. | BACKGROUND: Soybean residue (okara) is an agricultural by-product, which is rich in protein and fiber. This study evaluated a novel sequential process which combined fungal pretreatment (F) and twin screw extruder (E), to hydrolyze okara. The sequence of the pretreatment steps, and extruder at screw speeds 200 rpm (200... | ['Basidiomycota', 'Carotenoids', 'Fermentation', 'Food Handling', 'Plant Extracts', 'Soybeans', 'Waste Products'] | 30,411,355 | [['B01.300.179'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['G02.111.158.249', 'G03.191.249'], ['J01.576.423.200'], ['D20.215.784.500', 'D26.667'], ['B01.650.940.800.575.912.250.401.750'], ['D20.944', 'N06.850.460.710']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effect of frozen/thawed embryo transfer on birthweight, macrosomia, and low birthweight rates in US singleton infants. | BACKGROUND: Singleton infants conceived using assisted reproductive technology have lower average birthweights than naturally conceived infants and are more likely to be born low birthweight (<2500 gr). Lower birthweights are associated with increased infant and child mortality and poor adult health outcomes, including... | ['Adult', 'Birth Weight', 'Cryopreservation', 'Databases, Factual', 'Embryo Transfer', 'Embryo, Mammalian', 'Female', 'Fertilization in Vitro', 'Fetal Macrosomia', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Male', 'Pregnancy', 'Sex Factors', 'United States'] | 29,291,410 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['L01.313.500.750... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Coenrollment in a randomized trial of high-frequency oscillation: prevalence, patterns, predictors, and outcomes*. | OBJECTIVE: Enrollment of individual patients into more than one study has been poorly evaluated. The objective of this study was to describe the characteristics of patients, researchers and centers involved in coenrollment, studies precluding coenrollment, and the prevalence, patterns, predictors, and outcomes of coenr... | ['APACHE', 'Adult', 'Age Factors', 'Aged', 'Canada', 'Female', 'High-Frequency Ventilation', 'Hospital Bed Capacity', 'Hospital Mortality', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Randomized Controlled Trials as Topic', 'Research Design', 'Research Personnel', 'Resea... | 25,393,702 | [['E05.318.308.980.438.475.365', 'E05.318.308.980.438.475.456.500.250', 'N05.715.360.300.800.438.375.364.500.250', 'N06.850.520.308.980.438.475.364.500.250'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.107.567.176'], ['E02.041.625.508', 'E02.880.820.508'], ['N02.278.306.472'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Detection of hepatitis C virus-specific antigens in semen from non-A, non-B hepatitis patients. | Semen samples from nine patients clinically diagnosed as having non-A, non-B hepatitis (NANBH) were tested by an ELISA using antibodies raised in rabbits against HCV-specific antigens. The semen from all nine patients had elevated levels of HCV-specific antigen in comparison to semen from five healthy donors. Semen fro... | ['Antibody Specificity', 'Antigens, Viral', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Hepacivirus', 'Hepatitis Antibodies', 'Hepatitis C', 'Humans', 'Male', 'Semen', 'Sexually Transmitted Diseases, Viral', 'Viral Nonstructural Proteins'] | 1,373,358 | [['G12.100'], ['D23.050.327'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D23.050.550'], ['B04.450.380', 'B04.820.578.344.475'], ['D12.776.124.486.485.114.254.450', 'D12.776.124.790.651.114.254.450', 'D12.776.377.715.548.114.254.450'], ['C01.22... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proteomics-based expression library screening (PELS): a novel method for rapidly defining microbial immunoproteomes. | Current methodologies for global identification of microbial proteins that elicit host humoral immune responses have several limitations and are not ideally suited for use in the postgenomic era. Here we describe a novel application of proteomics, proteomics-based expression library screening, to rapidly define microbi... | ['Animals', 'Antibodies, Bacterial', 'Antigens, Bacterial', 'Cattle', 'Electrophoresis, Gel, Two-Dimensional', 'Escherichia coli O157', 'Escherichia coli Proteins', 'Gene Library', 'Mass Spectrometry', 'Proteome', 'Recombinant Proteins'] | 16,737,953 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.401.250', 'E05.301.300.230'], ['B03.440.450.425.325.300.800.250.500', 'B03.660.250.150.180.100.800.250.500'], ['D12.776.097.275'], ['G05.360.32... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cost of hospital care for HIV/AIDS infected patients in three general reference hospitals in Lubumbashi, DR Congo: prospective cohort study. | INTRODUCTION: This article analyses the composition of healthcare costs for HIV/AIDS infected patients in a country with limited resources and attempts to identify the factors that influence these costs. The aims are to calculate medical care costs, analysing how they vary depending on patients' income, and to evaluate... | ['AIDS-Related Opportunistic Infections', 'Adolescent', 'Adult', 'Anti-Retroviral Agents', 'CD4 Lymphocyte Count', 'Cohort Studies', 'Democratic Republic of the Congo', 'Educational Status', 'Female', 'HIV Infections', 'Hospital Costs', 'Hospitals, General', 'Humans', 'Income', 'Male', 'Middle Aged', 'Young Adult'] | 24,198,878 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.388.077'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.5... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Corneal graft rejection: a new rabbit model and cyclosporin-A. | In order to test the efficacy of topically applied cyclosporin-A in preventing corneal allograft rejection, existing rabbit models were modified to produce a new model in which the allograft reaction could be consistently initiated solely as a result of corneal transfer without any additional means of sensitisation. Wi... | ['Animals', 'Corneal Transplantation', 'Cyclosporins', 'Drug Administration Schedule', 'Graft Rejection', 'Models, Biological', 'Rabbits'] | 7,041,957 | [['B01.050'], ['E02.095.147.725.225', 'E04.540.825.374', 'E04.936.580.225'], ['D04.345.566.235', 'D12.644.641.235'], ['E02.319.283'], ['G12.875.545.328'], ['E05.599.395'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions of grape seed tannins with salivary proteins. | To evaluate the amount and type of condensed tannins binding salivary proteins, which are supposed to be involved in astringent sensation, model systems allowing further analyses of proteins and condensed tannins were developed. The precipitates formed after addition of grape seed tannins to salivary proteins indicate ... | ['Electrophoresis, Polyacrylamide Gel', 'Rosales', 'Salivary Proteins and Peptides', 'Seeds', 'Tannins'] | 10,563,846 | [['E05.196.401.402', 'E05.301.300.319'], ['B01.650.940.800.575.912.250.859.937'], ['D12.644.848', 'D12.776.850'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D05.750.078.937']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1. | Gating modifier toxins (GMTs) from spider venom can inhibit voltage gated sodium channels (NaVs) involved in pain signal transmission, including the NaV1.7 subtype. GMTs have a conserved amphipathic structure that allow them to interact with membranes and also with charged residues in regions of NaV that are exposed at... | ['Animals', 'Humans', 'Peptides', 'Spider Venoms'] | 30,507,158 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644'], ['D20.888.065.870', 'D23.946.833.065.870']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of microplastics in wetland samples from coastal Ghana using the Rose Bengal stain. | The use of optical microscope remains the most commonly used technique for microplastic identification and quantification despite major limitations with misidentifications and biases. We evaluated the use of the 1% Rose Bengal stain in improving the identification of microplastics after a standard microplastic isolatio... | ['Coloring Agents', 'Environmental Monitoring', 'Ghana', 'Microplastics', 'Rose Bengal', 'Water Pollutants, Chemical', 'Wetlands'] | 32,128,624 | [['D27.720.233'], ['N06.850.460.350.080', 'N06.850.780.375'], ['Z01.058.290.190.320'], ['D05.750.716.294', 'D25.720.716.294', 'J01.637.051.720.716.294'], ['D02.455.426.779.347.700', 'D03.633.300.953.275.700', 'D04.711.347.700'], ['D27.888.284.903.655'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[Clinical profile of Chagas and non-Chagas' disease patients with cardiac pacemaker]. | The aim of this study was to compare Chagas and non-Chagas' disease patients using single or dual-chamber pacemaker in relation to the ejection fraction of the left ventricle, the ventricular stimulation threshold and the occurrence of ventricular arrhythmia. From January, 2001 to November, 2002, 45 Chagas' disease pat... | ['Aged', 'Cardiac Pacing, Artificial', 'Chagas Cardiomyopathy', 'Echocardiography', 'Electrocardiography, Ambulatory', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prognosis', 'Tachycardia, Ventricular', 'Telemetry', 'Ventricular Function, Left'] | 16,906,246 | [['M01.060.116.100'], ['E02.331.200'], ['C01.610.752.300.900.200.190', 'C01.920.625.190', 'C14.280.238.190'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Perfluorochemicals as liver- and spleen-seeking ultrasound contrast agents. | In this study, Fluosol-DA, 20 per cent (composed of perfluorodecalin and perfluorotripropylamine) was tested as a liver-specific ultrasound contrast agent. Twelve normal rabbits were scanned, utilizing the Picker Microview (10 MHz), prior to and two days following the intravenous administration of 24 ml/kg of Fluosol (... | ['Animals', 'Contrast Media', 'Drug Combinations', 'Fluorocarbons', 'Hydroxyethyl Starch Derivatives', 'Kidney', 'Liver', 'Rabbits', 'Spleen', 'Ultrasonography'] | 6,854,723 | [['B01.050'], ['D27.505.259.500', 'D27.720.259'], ['D26.310'], ['D02.455.526.510.435'], ['D09.301.915.500', 'D09.698.365.855.500'], ['A05.810.453'], ['A03.620'], ['B01.050.150.900.649.313.968.700'], ['A10.549.700', 'A15.382.520.604.700'], ['E01.370.350.850']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites. | The epidermal growth factor receptor (EGFR) kinase catalyzes phosphorylation of tyrosines in its C terminus and in other cellular targets upon epidermal growth factor (EGF) stimulation. Here, by using peptides derived from EGFR autophosphorylation sites and cellular substrates, we tested the hypothesis that ligand may ... | ['Adaptor Proteins, Signal Transducing', 'Adaptor Proteins, Vesicular Transport', 'Animals', 'Binding Sites', 'Blotting, Western', 'COS Cells', 'Catalytic Domain', 'Cell Line', 'DNA, Complementary', 'Dose-Response Relationship, Drug', 'Enzyme Activation', 'Epidermal Growth Factor', 'Epitopes', 'ErbB Receptors', 'Glutat... | 15,231,819 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.543.990.150'], ['B01.050'], ['G02.111.570.120'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210.172.500', 'A11.329.228.220'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laparoscopic sleeve gastrectomy: a retrospective review of 1- and 2-year results. | INTRODUCTION: Recently, laparoscopic sleeve gastrectomy (LSG) has been added as a surgical treatment for obesity. We report our 1- and 2-year results with LSG.METHODS: From September 2005, we have performed 247 LSGs. We retrospectively reviewed our 1- and 2-year data to assess weight loss, body mass index (BMI), percen... | ['Adult', 'Body Mass Index', 'Diabetes Mellitus, Type 2', 'Female', 'Gastrectomy', 'Humans', 'Laparoscopy', 'Length of Stay', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Postoperative Complications', 'Retrospective Studies', 'Treatment Outcome', 'Weight Loss'] | 19,690,918 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.149', 'C19.246.300'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
EEG spatiospectral patterns and their link to fMRI BOLD signal via variable hemodynamic response functions. | BACKGROUND: Spatial and temporal resolution of brain network activity can be improved by combining different modalities. Functional Magnetic Resonance Imaging (fMRI) provides full brain coverage with limited temporal resolution, while electroencephalography (EEG), estimates cortical activity with high temporal resoluti... | ['Adult', 'Cerebrum', 'Electroencephalography', 'Female', 'Functional Neuroimaging', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Nerve Net', 'Neurovascular Coupling', 'Psycholinguistics', 'Visual Perception', 'Young Adult'] | 30,802,472 | [['M01.060.116'], ['A08.186.211.200.885.287'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.350.578.875', 'E01.370.376.537.625', 'E05.629.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.511'], ['G09.330.100.159.500'], ['F02.694', 'F04.096.586', 'L01.559.598.628'], ['F02.463.5... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Kujigamberol, a new dinorlabdane diterpenoid isolated from 85million years old Kuji amber using a biotechnological assay. | A new compound, 15,20-dinor-5,7,9-labdatriene-18-ol (1), named kujigamberol, was isolated from amber, fossilized tree resin from the Kuji area in Japan, has been dated as being 85 million years old (late Cretaceous). Kujigamberol was identified using the hypersensitive mutant yeast (zds1? erg3? pdr1? pdr3?) with respec... | ['Amber', 'Antineoplastic Agents, Phytogenic', 'Calcium', 'Diterpenes', 'Enzyme Inhibitors', 'Fossils', 'Glycogen Synthase Kinase 3', 'Glycogen Synthase Kinase 3 beta', 'HL-60 Cells', 'Humans', 'Japan', 'Molecular Structure', 'Phytotherapy', 'Plant Extracts', 'Signal Transduction', 'Yeasts'] | 22,507,387 | [['D05.750.078.840.109', 'D20.215.721.500.109'], ['D27.505.954.248.179'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.455.849.291'], ['D27.505.519.389'], ['I01.076.368.584.311'], ['D05.500.117.875', 'D08.811.913.696.620.682.700.429.500', 'D08.811.913.696.620.682.700.646.625', 'D12.644.360.300.500', 'D1... | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Comparing the priorities of parents and young people with cerebral palsy. | PURPOSE: Adolescence is a period of change and transition that may pose unique challenges for young people with cerebral palsy (CP). We compared statements of priorities, i.e. what adolescents (13-17) and youth (18-21) and their parents would like to be able to do to enable greater activity and participation.METHODS: P... | ['Adolescent', 'Analysis of Variance', 'Cerebral Palsy', 'Chi-Square Distribution', 'Comorbidity', 'Cross-Sectional Studies', 'Disabled Children', 'Female', 'Health Priorities', 'Humans', 'Interviews as Topic', 'Male', 'Parents', 'Statistics, Nonparametric', 'United States', 'Young Adult'] | 21,192,775 | [['M01.060.057'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C10.228.140.140.254'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Low risk of mother-to-child transmission of human T lymphotropic virus type II in non-breast-fed infants. The NYC Perinatal HIV Transmission Collaborative Study. | The transmissibility of human T lymphotropic virus (HTLV) type II from mother to child was investigated. Of 236 women enrolled during pregnancy in a study of mother-to-child transmission of human immunodeficiency virus in 1986-1988, 21 (8.9%) were seropositive for HTLV-I/II. All 21 mothers were infected with HTLV-II by... | ['Adult', 'Blotting, Western', 'Breast Feeding', 'Female', 'HTLV-II Antibodies', 'HTLV-II Infections', 'Human T-lymphotropic virus 2', 'Humans', 'Infant', 'Infant, Newborn', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Risk Factors'] | 1,527,426 | [['M01.060.116'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['D12.776.124.486.485.114.254.150.510', 'D12.776.124.790.651.114.254.150.510', 'D12.776.377.715.548.114.254.150... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
No transfer of calibration between action and perception in learning a golf putting task. | We assessed calibration of perception and action in the context of a golf putting task. Previous research has shown that right-handed novice golfers make rightward errors both in the perception of the perfect aiming line from the ball to the hole and in the putting action. Right-handed experts, however, produce accurat... | ['Athletic Performance', 'Discrimination, Psychological', 'Distance Perception', 'Female', 'Functional Laterality', 'Golf', 'Humans', 'Individuality', 'Male', 'Orientation', 'Psychophysics', 'Transfer, Psychology', 'Visual Perception', 'Young Adult'] | 21,814,859 | [['I03.450.642.845.054'], ['F02.463.593.257'], ['F02.463.593.200.390', 'F02.463.593.778.255.390'], ['F02.830.297.425', 'G11.561.225.425'], ['I03.450.642.845.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F01.058.577', 'F02.830.606'], ['E01.370.685', 'F04.096.753'], ['F02.463.425.910'], ['F02... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Evolution, three-dimensional model and localization of truncated hemoglobin PttTrHb of hybrid aspen. | Thus far, research on plant hemoglobins (Hbs) has mainly concentrated on symbiotic and non-symbiotic Hbs, and information on truncated Hbs (TrHbs) is scarce. The aim of this study was to examine the origin, structure and localization of the truncated Hb (PttTrHb) of hybrid aspen (Populus tremula L. ? tremuloides Michx.... | ['Amino Acid Sequence', 'Biological Evolution', 'Gene Expression Regulation, Plant', 'Heme', 'Hybridization, Genetic', 'Models, Molecular', 'Molecular Sequence Data', 'Phylogeny', 'Plant Leaves', 'Plant Stems', 'Plants, Genetically Modified', 'Populus', 'Protein Transport', 'RNA Interference', 'Sequence Alignment', 'St... | 24,520,401 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G05.045', 'G16.075'], ['G05.308.375'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['E05.820.150.390', 'G05.090.390'], ['E05.599.595'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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