Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diffuse Lewy body disease: an autopsy case. | A 67-year-old male patient initially showed memory disturbance followed by tremors a year later. The symptoms rapidly aggravated to dementia and Parkinsonian symptoms, and the patient died 2 years and 6 months after the onset at the age of 69 years and 5 months. Autopsy revealed numerous senile plaques in the cerebral ... | ['Aged', 'Alzheimer Disease', 'Brain Stem', 'Cerebral Cortex', 'Hippocampus', 'Humans', 'Inclusion Bodies', 'Male', 'Neurofibrils', 'Parkinson Disease', 'Temporal Lobe'] | 2,820,201 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211.132'], ['A08.186.211.200.885.287.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.420'], ['A08.675.609', 'A11.284.430.214.190.750.640', 'A11.671... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Great vesicovaginal fistula after normal vaginal delivery in a developed country]. | BACKGROUND: Obstetric fistulas in developed countries are infrequent and have been associated with instrumental vaginal delivery, manual removal of placenta and surgical complications during caesarean section. We present the diagnosis and treatment of an obstetric fistula of patient without clear risk factors in a deve... | ['Adult', 'Cystoscopy', 'Delivery, Obstetric', 'Female', 'Hematuria', 'Humans', 'Infant, Newborn', 'Male', 'Pregnancy', 'Spain', 'Vesicovaginal Fistula'] | 27,290,804 | [['M01.060.116'], ['E01.370.388.250.180', 'E01.370.390.175', 'E04.502.250.180', 'E04.950.774.155'], ['E04.520.252'], ['C12.777.934.442', 'C13.351.968.934.442', 'C23.550.414.849'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769'], ['Z01.542.846'], ['C13.351.500.894.767.500', 'C13... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
A Dual Role Hypothesis of the Cortico-Basal-Ganglia Pathways: Opponency and Temporal Difference Through Dopamine and Adenosine. | The hypothesis that the basal-ganglia direct and indirect pathways represent goodness (or benefit) and badness (or cost) of options, respectively, explains a wide range of phenomena. However, this hypothesis, named the Opponent Actor Learning (OpAL), still has limitations. Structurally, the OpAL model does not incorpor... | ['Adenosine', 'Animals', 'Basal Ganglia', 'Cerebral Cortex', 'Dopamine', 'Dopaminergic Neurons', 'Humans', 'Models, Neurological', 'Neural Pathways', 'Neuronal Plasticity', 'Receptor, Adenosine A2A', 'Receptors, Dopamine D2', 'Reinforcement, Psychology'] | 30,687,019 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['A08.186.211.200.885.287.249'], ['A08.186.211.200.885.287.500'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['A08.675.278', 'A11.671.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of intracuff alkalinized 2% lidocaine on endotracheal tube cuff pressure and postoperative throat symptoms in anaesthesia maintained by nitrous oxide. | Aim To compare the effects of endotracheal tube cuff inflation media, air, saline and alkalinized 2% lidocaine on increase of cuff pressure (CP) during nitrous oxide maintained anaesthesia and on incidence of postoperative throat symptoms (PTS), and to evaluate the incidence of postoperative throat mucosal injuries (PT... | ['Adult', 'Aged', 'Anesthesia', 'Anesthetics', 'Double-Blind Method', 'Female', 'Humans', 'Intubation, Intratracheal', 'Lidocaine', 'Male', 'Middle Aged', 'Nitrous Oxide', 'Pharyngitis', 'Postoperative Complications', 'Pressure', 'Prospective Studies', 'Treatment Outcome'] | 30,680,980 | [['M01.060.116'], ['M01.060.116.100'], ['E03.155'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['D02.065.199.092.500', 'D02.092.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Right atrial hemangioma. | A case of right atrial hemangioma as a rare tumor of the heart is reported. Because of its single, pedunculated mass, surgical excision of the tumor resulted in the complete treatment. Histologically, it was classified as arteriolar type. The importance of recent non-invasive techniques to diagnose these tumors during ... | ['Echocardiography', 'Heart Atria', 'Heart Neoplasms', 'Hemangioma', 'Humans', 'Male', 'Middle Aged'] | 3,209,609 | [['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.541.358'], ['C04.588.894.309', 'C14.280.459'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of autoantibody against beta-amyloid peptide in the serum of elderly. | Alzheimer's disease (AD) is characterized by two major neurological features: amyloid deposits and neurofibrillary tangles in the brain. According to the amyloid cascade hypothesis, accumulation of amyloid-beta peptide (A-beta) plays a central role in the pathogenesis of AD. Several lines of evidence suggest that antib... | ['Adult', 'Aged', 'Aged, 80 and over', 'Amyloid beta-Peptides', 'Animals', 'Autoantibodies', 'Case-Control Studies', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Transgenic', 'Middle Aged'] | 19,273,318 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Implementation of a successful lifestyle intervention programme for New Zealand Maori to reduce the risk of type 2 diabetes and cardiovascular disease. | Lifestyle programmes have been shown to reduce the risk of type 2 diabetes in European populations. The participation of Maori in many mainstream health programmes is poor. This study evaluates a lifestyle intervention programme which is acceptable to Maori and which has objective outcome measures to determine the effe... | ['Adult', 'Biomarkers', 'Blood Glucose', 'Body Composition', 'Body Mass Index', 'Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Exercise Test', 'Fasting', 'Feeding Behavior', 'Female', 'Health Plan Implementation', 'Humans', 'Insulin', 'Insulin Resistance', 'Life Style', 'Male', 'Middle Aged', 'New Zealand', '... | 14,672,866 | [['M01.060.116'], ['D23.101'], ['D09.947.875.359.448.500'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['C18.452.394.750.149', 'C19.246.300'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['F01.145.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A preliminary study to assess the use of a "Snakes and Ladders" board game in improving the knowledge of elementary school children about taeniasis. | The Snakes and Ladders board game was modified so that it contained information on taeniasis. A quantitative approach was used to evaluate if elementary school children were able to answer correctly more questions about Taenia saginata and Taenia solium transmission and control after playing the game compared to before... | ['Animals', 'Child', 'Cysticercosis', 'Female', 'Games, Recreational', 'Humans', 'Indonesia', 'Knowledge', 'Male', 'Memory and Learning Tests', 'Records', 'Schools', 'Surveys and Questionnaires', 'Taenia saginata', 'Taenia solium', 'Taeniasis'] | 31,369,727 | [['B01.050'], ['M01.060.406'], ['C01.610.335.190.902.185'], ['I03.450.642.693.465'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['K01.468'], ['F04.711.513.401'], ['E05.318.308.940', 'L01.399.250.900', 'N04.452.859', 'N05.715.360.300.715', 'N06.850.520.308.940'], ['I02.783', 'J0... | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Technology,... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Evidence of complete cellular repair of 1,N6-ethenoadenine, a mutagenic and potential damage for human cancer, revealed by a novel method. | 1,N6-Ethenoadenine (epsilonA) is generated endogenously by lipid peroxidation and exogenously by tumorigenic industrial agents, vinyl chloride, and vinyl carbamate. epsilonA detected in human tissues causes mutation and is implicated in liver, colon and lung cancers. N-methyl purine DNA-glycosylase (MPG) is the only en... | ['Adenine', 'Animals', 'Biological Assay', 'Cell Cycle', 'Cell Extracts', 'DNA', 'DNA Damage', 'DNA Repair', 'HCT116 Cells', 'Humans', 'Mice', 'Mutagens', 'N-Glycosyl Hydrolases', 'Neoplasms', 'Restriction Mapping', 'Sensitivity and Specificity'] | 18,373,235 | [['D03.633.100.759.138'], ['B01.050'], ['E05.091'], ['G04.144'], ['D20.777.162'], ['D13.444.308'], ['G05.200'], ['G02.111.222', 'G05.219'], ['A11.251.210.190.380', 'A11.251.860.180.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.888.569.468'], ['D08.811.277.450... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Deteriorated visual backward masking in the shine-through effect in adolescents with psychosis. | Visual backward masking is a reliable and widely used tool in schizophrenia research. Whereas many studies have shown masking deficits in adult patients, there are only very few studies with adolescents with psychosis-and with controversial results. Masking deficits of adolescents are of primary interest because they a... | ['Adolescent', 'Analysis of Variance', 'Attention', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Neuropsychological Tests', 'Perceptual Disorders', 'Perceptual Masking', 'Photic Stimulation', 'Psychiatric Status Rating Scales', 'Visual Acuity'] | 19,031,325 | [['M01.060.057'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.104.214'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F04.711.513'], ['C10.597.606.762', 'C23.888.592.604.764', 'F01.700.750'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of field experiences on music therapy students' perceptions of choral music for geriatric wellness programs. | The purpose of the study was to examine the effect of field experiences on music therapy students' perceptions of choral music for geriatric wellness programs. Specifically, the study investigated music therapy students': a) personal comfort working with senior adult singers; b) perceptions of preparation in their educ... | ['Adult', 'Aged', 'Analysis of Variance', 'Attitude of Health Personnel', 'Female', 'Health Services for the Aged', 'Humans', 'Interpersonal Relations', 'Male', 'Music', 'Music Therapy', 'Preceptorship', 'Students', 'Surveys and Questionnaires', 'Time Factors'] | 15,762,837 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.100.050', 'N05.300.100'], ['N02.421.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['K01.602'], ['E02.190.888.500', 'E02.760.169.063.500.440', 'E02.831.440', 'F04.754.549'], ['I02.35... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Obstruction of the small intestine: accuracy and role of CT in diagnosis. | The reliability of abdominal computed tomography (CT) in the assessment of varying degrees of small bowel obstruction (SBO) was evaluated by using results at enteroclysis and clinical outcome as standards of reference. A blinded retrospective analysis was performed of the studies of 55 patients who underwent both CT an... | ['Double-Blind Method', 'False Negative Reactions', 'False Positive Reactions', 'Humans', 'Intestinal Obstruction', 'Intestine, Small', 'Retrospective Studies', 'Severity of Illness Index', 'Tomography, X-Ray Computed'] | 8,511,318 | [['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.354.340'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['A03.556.124.684'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Itinerant magnetism in metallic CuFe2Ge2. | Theoretical calculations are performed to understand the electronic structure and magnetic properties of CuFe2Ge2. The band structure reveals large electron density N(EF) at the Fermi level suggesting a strong itinerant character of magnetism. The Fermi surface is dominated by two dimensional sheet like structures, wit... | ['Electrons', 'Ferric Compounds', 'Magnetics', 'Metals', 'Temperature'] | 25,807,140 | [['G01.249.335', 'G01.358.500.750'], ['D01.490.100'], ['H01.671.493'], ['D01.552'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
SMART cognitive training combined with a parental coaching programme for three children treated for medulloblastoma. | In a pilot study we examined the feasibility of a condensed version of the Swedish Memory and Attention Re-Training on children treated for medulloblastoma combined with a structured coaching programme for their parents. Parental coaching contained the translation of the child's new skills into daily life, and educatio... | ['Adolescent', 'Brain Neoplasms', 'Child', 'Cognition Disorders', 'Executive Function', 'Family Health', 'Family Therapy', 'Female', 'Humans', 'Male', 'Medulloblastoma', 'Neuropsychological Tests', 'Parent-Child Relations', 'Parents', 'Pilot Projects', 'Self Concept', 'Stress, Psychological', 'Surveys and Questionnaire... | 20,203,375 | [['M01.060.057'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['F03.615.250'], ['F02.463.217'], ['N01.400.300'], ['F04.754.864.581.273'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.600.380.515', 'C04.557.465.625.600.590.500', 'C04.557.470.670.380.515', 'C04.55... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands. | AIMS: The typical ultrasound features of pleomorphic adenomas are considered to be the well-defined contour, the regular, sometimes lobulated shape, homogeneous structure and poor vascularization. The goal of our study was to verify the validity of these features and to identify a typical sonoelastographic pattern for ... | ['Adenolymphoma', 'Adenoma, Pleomorphic', 'Adolescent', 'Adult', 'Aged', 'Elasticity Imaging Techniques', 'Female', 'Humans', 'Male', 'Middle Aged', 'Necrosis', 'Prospective Studies', 'Salivary Gland Neoplasms', 'Sensitivity and Specificity', 'Ultrasonography, Doppler, Color'] | 21,203,593 | [['C04.557.435.075'], ['C04.557.435.090', 'C04.557.470.035.155'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.850.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.717'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Use of grafts in pelvic reconstructive surgery. | There has been growing interest in the use of grafts in pelvic reconstructive surgery. This article will address available graft materials and assess their clinical efficacy and safety. We conducted a Pubmed MEDLINE literature search for full-length English text studies with follow-up periods of at least one year. Ther... | ['Absorbable Implants', 'Bone Transplantation', 'Humans', 'Korea', 'Pelvic Bones', 'Postoperative Complications', 'Reconstructive Surgical Procedures', 'Treatment Outcome'] | 17,461,510 | [['E07.695.025'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.557', 'Z01.586.407'], ['A02.835.232.043.825'], ['C23.550.767'], ['E04.680'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Dissociation between steroid receptor expression and cell proliferation in the human breast. | We have shown previously that estradiol stimulates cell proliferation and progesterone receptor (PgR) synthesis in luminal epithelial cells of the normal human breast. Approximately 10-15% of luminal epithelial cells within the normal breast express immunodetectable estrogen receptor (ER), but little is known about the... | ['Biomarkers', 'Breast', 'Breast Neoplasms', 'Cell Division', 'Female', 'Humans', 'Ki-67 Antigen', 'Neoplasm Proteins', 'Receptors, Estradiol', 'Receptors, Progesterone'] | 9,371,488 | [['D23.101'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660.625.500', 'D23.050.290.500', 'D23.101.140.400'], ['D12.776.624'], ['D12.776.826.750.350.350'], ['D12.776.826.750.765']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Confidence intervals for the between-study variance in random-effects meta-analysis using generalised heterogeneity statistics: should we use unequal tails? | BACKGROUND: Confidence intervals for the between study variance are useful in random-effects meta-analyses because they quantify the uncertainty in the corresponding point estimates. Methods for calculating these confidence intervals have been developed that are based on inverting hypothesis tests using generalised het... | ['Algorithms', 'Analysis of Variance', 'Bayes Theorem', 'Biometry', 'Computer Simulation', 'Confidence Intervals', 'Humans', 'Meta-Analysis as Topic', 'Models, Statistical'] | 27,604,952 | [['G17.035', 'L01.224.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.318.740.225', 'N06.850.505.200'], ['L01.224.160'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['B01.050.150.900.649... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A reliable, simple and cost-efficient TLC-HPLC method for simultaneously determining florfenicol and florfenicol amine in porcine urine: application to residue surveillance. | Violative residues of florfenicol (FF) in porcine edible tissues pose a potential risk for human health. In this study, urine was selected as target matrix for routine residue monitoring of FF in pig, and a thin layer chromatography (TLC)-high-performance liquid chromatography (HPLC) method was developed for simultaneo... | ['Animals', 'Anti-Bacterial Agents', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Drug Residues', 'Food Contamination', 'Swine', 'Thiamphenicol', 'Veterinary Drugs'] | 31,192,771 | [['B01.050'], ['D27.505.954.122.085'], ['E05.196.181.400.300'], ['E05.196.181.400.537'], ['N06.850.460.200.250'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.500.880'], ['D02.033.455.706.300.850', 'D02.455.426.559.389.565.175.850', 'D02.640.529.175.850'], ['D26.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Antiphospholipid Syndrome in Chronic Thromboembolic Pulmonary Hypertension: A Well-Defined Subgroup of Patients. | Antiphospholipid syndrome (APS) is an acquired thrombophilia with an uncertain role in the development of chronic thromboembolic pulmonary hypertension (CTEPH). We aimed to assess the association of APS with the clinical phenotype of CTEPH. We retrospectively reviewed data of CTEPH patients referred to our center. Clin... | ['Adult', 'Age Factors', 'Aged', 'Antibodies, Antiphospholipid', 'Antiphospholipid Syndrome', 'Autoimmune Diseases', 'China', 'Chronic Disease', 'Female', 'Hemodynamics', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Pulmonary Embolism', 'Retrospective Studies', 'Thromboembolism', 'Young Adult'] | 31,226,720 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323.210', 'D12.776.124.790.651.114.323.210', 'D12.776.377.715.548.114.323.210'], ['C20.111.197'], ['C20.111'], ['Z01.252.474.164'], ['C23.550.291.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The first successful DeBakey VAD child implantation as a bridge to transplant. | A 14-year-old boy with repaired transposition of the great arteries and ventricular septal defect presented with atrial flutter and severe congestive heart failure. Despite successful cardioversion and optimal medical therapy, the patient deteriorated and was supported with extracorporeal membrane oxygenation (ECMO). T... | ['Adolescent', 'Atrial Flutter', 'Equipment Design', 'Extracorporeal Membrane Oxygenation', 'Follow-Up Studies', 'Heart Failure', 'Heart Transplantation', 'Heart-Assist Devices', 'Humans', 'Male', 'Prosthesis Implantation', 'Time Factors', 'Treatment Outcome'] | 16,322,739 | [['M01.060.057'], ['C14.280.067.248', 'C23.550.073.248'], ['E05.320'], ['E02.880.301', 'E04.292.451'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.37... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The relationship between the dietary inflammatory index and prevalence of radiographic symptomatic osteoarthritis: data from the Osteoarthritis Initiative. | PURPOSE: To investigate whether higher dietary inflammatory index (DII®) scores were associated with higher prevalence of radiographic symptomatic knee osteoarthritis in a large cohort of North American people from the Osteoarthritis Initiative database.METHODS: A total of 4358 community-dwelling participants (2527 fem... | ['Cohort Studies', 'Databases, Factual', 'Diet', 'Female', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Prevalence', 'Radiography', 'Risk Factors', 'Surveys and Questionnaires'] | 29,209,774 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E05.318.308.985.525.750', 'N01.224... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Dynamics of individual animal Bovine Herpes Virus-1 antibody status on 9 commercial dairy herds. | Bovine Herpes Virus 1 (BoHV-1) is an important viral disease of cattle worldwide. In endemically infected herds, there is an incomplete understanding of the epidemiology of BoHV-1 infection. We describe the dynamics of animal-level BoHV-1 antibody status on 9 endemically infected commercial dairy herds, based on the re... | ['Animals', 'Antibodies, Viral', 'Cattle', 'Cattle Diseases', 'Female', 'Herpesviridae Infections', 'Herpesvirus 1, Bovine', 'Infectious Bovine Rhinotracheitis', 'Milk', 'Seasons'] | 21,774,953 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C01.925.256.466'], ['B04.280.382.100.900.400'], ['C01.925.256.466.488', 'C22.196.429'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Evaluation of outpatient assessment after transurethral prostatectomy. | The need for a three-month visit at the outpatient clinic for assessment including uroflowmetry was retrospectively evaluated in 78 patients who underwent transurethral resection for benign prostatic hypertrophy during 1986. One patient died before discharge and six were lost to follow-up. Eleven patients requested app... | ['Aged', 'Aged, 80 and over', 'Ambulatory Care', 'Creatinine', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prostatectomy', 'Prostatic Hyperplasia', 'Urinary Tract Infections', 'Urination Disorders'] | 1,719,621 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.760.106', 'N02.421.585.106'], ['D03.383.129.308.207'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E04.950.774.860.625'], ['C12.294... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oral health care for Canterbury, New Zealand 13-14 year old students. | The study has demonstrated a high prevalence of dental caries and a uniformly high level of treatment across all major population groups of Canterbury 13-14 year olds. The treatment programme has the problem of dental caries under control but more attention should be directed to lowering caries prevalence and the need ... | ['Adolescent', 'DMF Index', 'Dental Care', 'Dental Caries', 'Female', 'Gingivitis', 'Humans', 'Male', 'New Zealand', 'Oral Hygiene', 'Periodontal Index'] | 1,067,231 | [['M01.060.057'], ['E05.318.308.980.438.300.350', 'E06.208.266', 'N05.715.360.300.800.438.300.340', 'N06.850.520.308.980.438.300.350', 'N06.890.160.100'], ['E06.170', 'N02.421.240.190'], ['C07.793.720.210'], ['C01.408', 'C07.465.714.258.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.67... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Clinical application of high-frequency oscillatory ventilation for the treatment of neonatal pneumothorax]. | OBJECTIVE: To evaluate the clinical effect of high-frequency oscillatory ventilation (HFOV) for the treatment of neonatal pneumothorax.METHODS: Retrospective analysis was performed on the clinical data of 23 neonates with pneumothorax who received HFOV from January 2007 to June 2011. Of the 23 cases, 19 cases were trea... | ['Female', 'High-Frequency Ventilation', 'Humans', 'Infant, Newborn', 'Male', 'Oxygen', 'Pneumothorax', 'Retrospective Studies'] | 22,809,600 | [['E02.041.625.508', 'E02.880.820.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D01.268.185.550', 'D01.362.670'], ['C08.528.778'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of type 2 diabetes mellitus on the population pharmacokinetics of rifampin in tuberculosis patients. | Diabetes mellitus (DM) is a well-known risk factor to develop tuberculosis (TB). Some reports indicate the serum concentrations of anti-TB drugs are lower in patients with TB and DM than those with TB only. Therefore, we developed a nonlinear mixed-effects model (NONMEM) to determine the population PK parameters of rif... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antibiotics, Antitubercular', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Chemical', 'Prospective Studies', 'Rifampin', 'Tuberculosis, Pulmonary', 'Young Adult'] | 25,482,224 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085.255.135'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.495'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['D03... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Change in automaticity of excised, sino-atrial node by alprenolol and its dextro isomer and several drugs injected into the sinus node artery of the dog. | Effects of several drugs on the automaticity of blood-perfused canine sino-atrial node preparation were examined by injecting drugs into the sinus node artery. All drugs produced a dose-dependent decrease in sino-atrial rate, although dl-alprenolol in low doses produced a slight increase, and their relative potencies d... | ['Adenosine', 'Alprenolol', 'Animals', 'Calcium', 'Dogs', 'Female', 'Heart Rate', 'Injections, Intra-Arterial', 'Male', 'Nifedipine', 'Procaine', 'Propranolol', 'Quinidine', 'Sinoatrial Node', 'Stereoisomerism', 'Tetrodotoxin'] | 603,319 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D02.033.100.624.698.055', 'D02.033.755.624.698.055', 'D02.092.063.624.698.055'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E02.319.26... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Actions of 8-bromo-cyclic-GMP on neurones in the rat thalamus in vivo and in vitro. | The diffusible intercellular messenger nitric oxide may have a modulatory role in the thalamus and this action may be mediated via activation of soluble guanylate cyclase. In order to investigate this possibility, we applied the cyclic-GMP analogue 8-Bromo-cyclic-GMP (8-Br-cGMP) onto neurones in the ventrobasal and lat... | ['Action Potentials', 'Animals', 'Cyclic GMP', 'Evoked Potentials, Visual', 'Excitatory Amino Acid Agonists', 'Geniculate Bodies', 'Guanylate Cyclase', 'In Vitro Techniques', 'Molsidomine', 'N-Methylaspartate', 'Neurons, Afferent', 'Nitric Oxide', 'Nitric Oxide Donors', 'Rats', 'Rats, Wistar', 'alpha-Amino-3-hydroxy-5-... | 10,375,703 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['A08.186.211.200.317.826.701.444'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are lipid-lowering drugs associated with a risk of cataract? A pharmacovigilance study. | Some reports have raised concerns regarding a potential risk of cataracts associated with statins. However, clinical and observational studies evaluating the risk led to conflicting results. We assessed whether lipid-lowering drugs (LLD) use is associated with an increased risk of cataract using the WHO's Individual Ca... | ['Aged', 'Aged, 80 and over', 'Cataract', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Hypolipidemic Agents', 'Male', 'Middle Aged', 'Niacin', 'Pharmacovigilance', 'Proprotein Convertase 9', 'Risk'] | 31,251,421 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.510.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['D27.505.519.186.071', 'D27.505.954.557.500'], ['M01.060.116.630'], ['D03.066.515.475', 'D03.383.725.547.475'], ['E05.3... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A cost-effectiveness analysis of the diagnostic strategies for differentiating focal nodular hyperplasia from hepatocellular adenoma. | OBJECTIVES: We evaluated the cost-effectiveness of a gadoxetic acid-enhanced MRI (EOB-MRI) strategy compared with conventional MRI strategy and biopsy to differentiate focal nodular hyperplasia (FNH) from hepatocellular adenoma (HCA).METHODS: A decision tree model was constructed to compare the cost-effectiveness of EO... | ['Adenoma, Liver Cell', 'Adult', 'Contrast Media', 'Cost-Benefit Analysis', 'Decision Trees', 'Diagnosis, Differential', 'Female', 'Focal Nodular Hyperplasia', 'Gadolinium DTPA', 'Humans', 'Image Enhancement', 'Liver', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Male', 'Medicare', 'Middle Aged', 'Republic of Kore... | 28,726,119 | [['C04.557.470.035.120', 'C04.588.274.623.040', 'C06.301.623.040', 'C06.552.697.040'], ['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['N03.219.151.125'], ['G17.162.500'], ['E01.171'], ['C06.552.270'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Severe exacerbation of liver disease during pregnancy in a thalassemic GBV-C/HGV-positive patient and neonatal hepatitis in offspring. | The case of a young woman with GB virus C/hepatitis G virus (GBV-C/HGV) infection and with a severe exacerbation of chronic hepatitis of unknown etiology during pregnancy is described. In the offspring, severe neonatal hepatitis with subsequent mild chronic liver disease of at least 16-month duration was followed by th... | ['Adult', 'Antibodies, Viral', 'Biopsy, Needle', 'Female', 'Flaviviridae', 'Hepatitis, Viral, Human', 'Humans', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Interferon-alpha', 'Liver Function Tests', 'Polymerase Chain Reaction', 'Pregnancy', 'Pregnancy Complications, Infectious', 'RNA, Viral', 'beta... | 9,892,395 | [['M01.060.116'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B04.820.578.344'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Complete genome sequence of a novel species of Porcine Bocavirus, PBoV5. | Porcine bocavirus 5 is a novel porcine bocavirus species found in a pig with clinical diarrhea from a farm in China. Here, we report the complete genome sequence of strain PBoV5/JS677, which will help toward understanding the molecular and evolutionary characteristics of the porcine bocavirus. | ['Animals', 'Base Sequence', 'Bocavirus', 'China', 'Diarrhea', 'Feces', 'Genome, Viral', 'Molecular Sequence Data', 'Parvoviridae Infections', 'Sus scrofa', 'Swine', 'Swine Diseases'] | 22,205,722 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B04.280.580.650.085'], ['Z01.252.474.164'], ['C23.888.821.214'], ['A12.459'], ['G05.360.340.358.840'], ['L01.453.245.667'], ['C01.925.256.700'], ['B01.050.150.900.649.313.500.880.399'], ['B01.050.150.900.649.313.500.880'], ['C22.905']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Asymmetric synthesis of chiral ä-lactones containing multiple contiguous stereocenters. | A versatile methodology for the asymmetric synthesis of chiral ä-lactones containing multiple contiguous stereocenters has been developed that relies on a series of Evans' aldol, hydroxyl-directed cyclopropanation, methanolysis, and Hg(II) mediated cyclopropane ring-opening reactions for stereocontrol. | ['Chemistry, Organic', 'Cyclopropanes', 'Lactones', 'Mercury', 'Molecular Structure', 'Stereoisomerism'] | 21,671,632 | [['H01.181.404'], ['D02.455.426.392.368.533'], ['D02.540'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['G02.111.570', 'G02.466'], ['G02.607.445.682']] | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Progressive neuronal loss induced by kindling: a possible mechanism for mossy fiber synaptic reorganization and hippocampal sclerosis. | Kindling of limbic structures induces synaptic reorganization of the mossy fiber pathway in the dentate gyrus. To evaluate the hypothesis that kindling stimulation may also cause neuronal loss in the hilus of the dentate gyrus that could play a role in this synaptic reorganization, neuron counts were obtained using qua... | ['Animals', 'Cell Count', 'Electric Stimulation', 'Electrodes, Implanted', 'Hippocampus', 'Kindling, Neurologic', 'Male', 'Nerve Fibers', 'Neurons', 'Rats', 'Rats, Inbred Strains', 'Sclerosis', 'Synapses'] | 2,282,474 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G11.561.484'], ['A08.675.542', 'A11.671.501'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Epidemiology of obesity among the adult population of Catalonia]. | Several epidemiological studies have shown that obesity is related to the mortality from cardiovascular disease. In this study, the epidemiology of obesity and the correlation between body mass index and other cardiovascular risk factors was studied in a representative sample of the adult population of Catalonia. It wa... | ['Adolescent', 'Adult', 'Aged', 'Body Mass Index', 'Cardiovascular Diseases', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Risk Factors', 'Spain'] | 1,420,758 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of all-trans-retinoic on human gastric cancer cells BGC-823. | OBJECTIVE: To determine the inhibitory effects of all-trans-retinoic acid (ATRA) on cell growth, cell cycle and vascular endothelial growth factor (VEGF) expression in the human gastric cancer cell line BGC-823 in vitro.METHODS: Human gastric cancer BGC-823 cells were treated with various concentrations of ATRA and the... | ['Antineoplastic Agents', 'Cell Cycle', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Humans', 'Stomach Neoplasms', 'Tretinoin', 'Tumor Cells, Cultured', 'Vascular Endothelial Growth Factor A'] | 17,261,132 | [['D27.505.954.248'], ['G04.144'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789'], ['D02.455.326.271.665.202.495.818.500', 'D02.455.426.392.368.367.379.249.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Causes and remedies for low research productivity among postgraduate scholars and early career researchers on non-communicable diseases in Nigeria. | OBJECTIVE: The aim of the descriptive, cross sectional, questionnaire-based study reported here was to explore the causes of low productivity in non-communicable diseases research among postgraduate scholars and early career researchers in Nigeria and identify measures that could facilitate increased research output.RE... | ['Academies and Institutes', 'Biomedical Research', 'Capacity Building', 'Cross-Sectional Studies', 'Humans', 'Nigeria', 'Noncommunicable Diseases', 'Research Personnel', 'Research Support as Topic', 'Surveys and Questionnaires', 'Universities'] | 31,307,552 | [['N03.540.052'], ['H01.770.644.145'], ['N02.138', 'N04.452.105'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.190.565'], ['C23.550.291.898'], ['M01.526.839'], ['N03.219.483.645'], ['E05.318.308.980', 'N05.715.360.300.800'... | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Atorvastatin mitigates testicular injuries induced by ionizing radiation in mice. | BACKGROUND: Radiotherapy in patients with pelvis malignancy causes testes irradiation and resulted in testicular damages. Atorvastatin (ATV) in the low-dose is considered as antioxidant and anti-inflammatory properties.OBJECTIVE: This experimental study was investigated protective effects of ATV on irradiation-induced ... | ['Animals', 'Atorvastatin', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Lipid Peroxidation', 'Male', 'Mice, Inbred BALB C', 'Radiation Injuries, Experimental', 'Radiation, Ionizing', 'Radiation-Protective Agents', 'Testicular Diseases', 'Testis', 'Testosterone'] | 28,668,617 | [['B01.050'], ['D03.383.129.578.075', 'D10.251.450.200'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['G02.111.515', 'G03.295.531.587'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['C26.733.720', 'E05.598.500.750', 'G01.750.748.500.720... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[DNA damage and apoptosis of human airway epithelial cell lines caused by cigarette smoke extract]. | BACKGROUND & OBJECTIVE: Cigarette smoke exposure has been reported to induce DNA damage in a variety of cell types. This study was to investigate DNA damage and apoptosis in normal human bronchial epithelial cell line NHBE and lung carcinoma cell line SPC-A1 caused by cigarette smoke extract.METHODS: NHBE and SPC-A1 ce... | ['Adenocarcinoma', 'Apoptosis', 'Bronchi', 'Cell Line', 'Cell Line, Tumor', 'DNA Breaks, Double-Stranded', 'DNA Damage', 'Dose-Response Relationship, Drug', 'Epithelial Cells', 'Histones', 'Humans', 'Lung Neoplasms', 'Phosphorylation', 'Smoke', 'Time Factors', 'Tobacco'] | 17,059,759 | [['C04.557.470.200.025'], ['G04.146.954.035'], ['A04.411.125'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.200.210.220'], ['G05.200'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Second-order receptive fields reveal multidigit interactions in area 3b of the macaque monkey. | Linear receptive field (RF) models of area 3b neurons reveal a three-component structure: a central excitatory region flanked by two inhibitory regions that are spatially and temporally nonoverlapping with the excitation. Previous studies also report that there is an "infield" inhibitory region throughout the neuronal ... | ['Action Potentials', 'Afferent Pathways', 'Animals', 'Brain Mapping', 'Linear Models', 'Macaca mulatta', 'Male', 'Models, Neurological', 'Neural Inhibition', 'Neurons', 'Nonlinear Dynamics', 'Physical Stimulation', 'Predictive Value of Tests', 'Somatosensory Cortex', 'Touch', 'Wakefulness'] | 22,457,468 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['A08.612.220'], ['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Immunohistochemical study of the palatine tonsils]. | This study reports on an immunohistochemical examination of the tonsils. For this purpose 10 clinically healthy tonsils, 15 with acute tonsillitis, 40 with chronic cryptic tonsillitis and 16 hyperplastic tonsils were studied by means of the direct immunofluorescent technique. With regard to the clinically healthy tonsi... | ['Adolescent', 'Adult', 'Child', 'Chronic Disease', 'Humans', 'Hyperplasia', 'Immunoglobulins', 'Lymphocytes', 'Microscopy, Fluorescence', 'Palatine Tonsil', 'Tonsillitis'] | 3,347,134 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['E01.370.350.515.458', 'E05.595.45... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The distribution and properties of RNA primed initiation sites of DNA synthesis at the replication origin of Escherichia coli chromosome. | RNA-linked DNA molecules were obtained from E. coli dnaCts cells synchronously initiating a new round of chromosome replication. The deoxynucleotides at the transition from primer RNA to DNA were 32P-labeled, and their positions were located on the nucleotide sequence of 1.4 kb genomic region (position -906 to +493) in... | ['Base Sequence', 'Chromosome Mapping', 'Chromosomes, Bacterial', 'DNA Replication', 'DNA, Bacterial', 'Escherichia coli', 'RNA, Bacterial'] | 2,414,732 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['G02.111.225', 'G05.226'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D13.444.735.473']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A qualitative study on the transfer of residents between a nursing home and an emergency department. | Nursing home (NH) residents who have exacerbations of chronic health conditions or new illnesses must generally go the emergency department (ED) for health care, later returning to the nursing home when it is felt that they are no longer require acute care. Transfers between settings of care are referred to as transiti... | ['Adult', 'Aged', 'Aged, 80 and over', 'Canada', 'Emergency Service, Hospital', 'Female', 'Geriatric Assessment', 'Homes for the Aged', 'Humans', 'Male', 'Nursing Homes', 'Outcome Assessment, Health Care', 'Patient Transfer'] | 21,438,866 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.176'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['J03.775.462', 'N02.278.825... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Prognostic implications of late gadolinium enhancement at the right ventricular insertion point in patients with non-ischemic dilated cardiomyopathy: A multicenter retrospective cohort study. | INTRODUCTION: The presence of late gadolinium enhancement (LGE) at the right ventricular insertion point (RVIP) on cardiac magnetic resonance (CMR) is generally believed to be nonspecific, but the clinical implication of this unique LGE pattern in patients with non-ischemic dilated cardiomyopathy (NICM) has not been el... | ['Cardiomyopathy, Dilated', 'Contrast Media', 'Echocardiography', 'Female', 'Follow-Up Studies', 'Gadolinium', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Survival Analysis'] | 30,485,353 | [['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['A07.541.560'... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antibiotic prescribing in 4 assisted-living communities: incidence and potential for improvement. | OBJECTIVE: To describe the prevalence, characteristics, and appropriateness of systemic antibiotic use in assisted living (AL) and to conduct a preliminary quality improvement intervention trial to reduce inappropriate prescribing.DESIGN: Pre-post study, with a 13-month intervention period.SETTING: Four AL communities.... | ['Anti-Bacterial Agents', 'Assisted Living Facilities', 'Humans', 'Inappropriate Prescribing', 'Incidence', "Practice Patterns, Physicians'", 'Quality Improvement'] | 25,222,900 | [['D27.505.954.122.085'], ['J03.775.187', 'N02.278.825.187'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.490', 'N02.421.450.500.249'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['N04.590.374.577', 'N05.300.625'], ['J01.293.754', 'N0... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The Decim system for the production of dental restorations. | The general background to the development of CAD/CAM is presented in short. Specific problems when using this technique for the manufacturing of dental restorations are emphasized, and then the reverse engineering and CAD/CAM process that have been implemented in the Decim (Dentronic AB, Skellefte?, Sweden) system are ... | ['Ceramics', 'Computer-Aided Design', 'Dental Materials', 'Dental Restoration, Permanent', 'Equipment Design', 'Humans', 'Inlays', 'Internet', 'Local Area Networks', 'Microcomputers', 'Software', 'Stress, Mechanical', 'Systems Integration', 'Yttrium', 'Zirconium'] | 11,351,484 | [['J01.637.153'], ['L01.224.108.150', 'L01.296.110.150'], ['D25.339', 'D27.720.102.339', 'J01.637.051.339'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.323.428.275', 'E06.780.346.737.500', 'E07.695.190.190.350'], ['L01.224.230.110.500'], ['... | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol. | BACKGROUND: Sodium polystyrene sulfonate (SPS, Kayexalate) has been implicated in the development of intestinal necrosis. Sorbitol, added as a cathartic agent, may be primarily responsible. Previous studies have documented bowel necrosis primarily in postoperative, dialysis, and transplant patients. We sought to identi... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cathartics', 'Cation Exchange Resins', 'Cohort Studies', 'Female', 'Humans', 'Hyperkalemia', 'Intestinal Mucosa', 'Ischemia', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Necrosis', 'Polystyrenes', 'Retrospective Studies', 'Sorbitol'] | 19,373,153 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.483.396'], ['D27.720.470.420.275'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.396'], ['A03.556.124.369', 'A10.615.550.444'], ['C23.550.513'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
A flow cytometric rosetting assay for the analysis of IgG-Fc receptor interactions. | We have developed a sensitive and flexible method for the qualitative evaluation of IgG-Fc receptor interactions in cell suspensions. The assay is based on the flow cytometric quantitation of antibody-coated erythrocyte (EA) rosetting using fluorescein-labelled indicator erythrocytes (E). The number of IgG molecules on... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, Differentiation', 'Flow Cytometry', 'Fluorescence', 'Humans', 'Immunoglobulin G', 'Immunoglobulin Isotypes', 'Mice', 'Receptors, Fc', 'Receptors, IgG', 'Rosette Formation'] | 2,138,200 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264', 'D23.101.100'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['G0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanical and structural response of a hybrid hydrogel based on chitosan and poly(vinyl alcohol) cross-linked with epichlorohydrin for potential use in tissue engineering. | The development and characterization of a hybrid hydrogel based on chitosan (CS) and poly(vinyl alcohol) (PVA) chemically cross-linked with epichlorohydrin (ECH) is presented. The mechanical response of these hydrogels was evaluated by uniaxial tensile tests; in addition, their structural properties such as average mol... | ['Cartilage', 'Chitosan', 'Elasticity', 'Epichlorohydrin', 'Guided Tissue Regeneration', 'Hydrogels', 'Mechanical Phenomena', 'Polyvinyl Alcohol', 'Tissue Engineering', 'Tissue Scaffolds', 'Viscosity'] | 24,007,370 | [['A02.165', 'A10.165.382'], ['D05.750.078.139.500', 'D09.698.211.500'], ['G01.374.590'], ['D02.355.291.411.400'], ['E04.680.300'], ['D20.280.320.375', 'D26.255.165.320.375'], ['G01.374'], ['D02.033.750', 'D02.455.326.271.884.533.532', 'D05.750.716.721.616', 'D25.720.716.721.616', 'J01.637.051.720.716.721.616'], ['E05.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Bioethics in the contemporary secular environment]. | The aim of this study is to determine the preventive function of bioethics as an independent scientific discipline in terms of predicting the future of mankind, figuring the patterns of potential bioethical problems and other global challenges and dilemmas. Wide diversity of axiological issues, mental representations ... | ['Bioethical Issues', 'Bioethics', 'Cloning, Organism', 'Embryo Research', 'Humans', 'Morals', 'Secularism', 'Suicide', 'Transplants'] | 23,293,235 | [['K01.752.566.479.023', 'N05.350.100'], ['K01.752.566.479.045', 'N05.350.200'], ['E05.393.240', 'E05.820.180'], ['E05.313', 'H01.770.644.145.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.500', 'K01.752.566'], ['I01.880.853.350', 'K01.922'], ['F01.145.126.980.875', 'I01.880.735.856'], ['A01.941']] | ['Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Noninvasive Quantification of Blood Flow in Epicardial Coronary Arteries, Coronary Artery Bypass Grafts, and Anastomoses. | OBJECTIVE: Direct flow measurement in native epicardial coronary arteries, bypass conduits, and anastomoses is severely limited by the invasiveness and inaccuracy of existing technologies. As a result, less than 25% of patients undergoing coronary artery bypass grafting (CABG) worldwide have any intraoperative evaluati... | ['Anastomosis, Surgical', 'Animals', 'Blood Flow Velocity', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Coronary Vessels', 'Disease Models, Animal', 'Hemorheology', 'Humans', 'Male', 'Swine'] | 28,129,321 | [['E04.035'], ['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.269', 'A07.015.908.194'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.830.250', 'G09... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Middle latency response to a 500-Hz tone pip in normal-hearing and in hearing-impaired subjects. | Measurement of middle latency responses (MLR) appears to be one of the most useful ways of determining low-frequency auditory threshold. It is known that analog filtering can drastically affect MLR and since most laboratories use different recording characteristics, we carried out these measurements with a number of fi... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Audiometry, Evoked Response', 'Audiometry, Pure-Tone', 'Auditory Threshold', 'Child', 'Female', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Middle Aged', 'Reaction Time'] | 3,406,656 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.382.375.060.050'], ['E01.370.382.375.060.055'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['M01.060.406'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Homeostasis and Disorder of Musculoskeletal System.Molecular mechanism of bone metabolism and future therapeutic strategies.] | Recent studies of mouse genetics and human gene mutations has greatly contributed to clarifying the molecular mechanism of bone metabolism. Bone is constantly renewed by the balanced action of osteoblastic bone formation and osteoclastic bone resorption both of which mainly occur at the bone surface. This restructuring... | ['Animals', 'Bone Remodeling', 'Bone and Bones', 'Homeostasis', 'Humans', 'Musculoskeletal Diseases', 'Osteoblasts', 'Osteocytes'] | 29,512,525 | [['B01.050'], ['G11.427.213', 'G16.762.150'], ['A02.835.232', 'A10.165.265'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05'], ['A11.329.629'], ['A11.329.629.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vitreous levels of the insulin-like growth factors I and II, and the insulin-like growth factor binding proteins 2 and 3, increase in neovascular eye disease. Studies in nondiabetic and diabetic subjects. | Retinal capillary nonperfusion results in neovascularization of the eye, which is restricted to the retina in less severe cases and progresses to the anterior chamber and the iris angle in the most advanced case, called rubeosis. This angioneogenesis may be induced by the release of retinal growth factors into the vitr... | ['Carrier Proteins', 'Diabetic Retinopathy', 'Eye Diseases', 'Female', 'Humans', 'Insulin-Like Growth Factor Binding Protein 2', 'Insulin-Like Growth Factor Binding Proteins', 'Insulin-Like Growth Factor I', 'Insulin-Like Growth Factor II', 'Ischemia', 'Male', 'Middle Aged', 'Radioimmunoassay', 'Retinal Vessels', 'Vitr... | 7,504,689 | [['D12.776.157'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['C11'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.420.260'], ['D12.776.157.420'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['D12.644.276.937.420', 'D12.776.124.862.425', 'D... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genesis of the ultradian rhythm of GH secretion: a new model unifying experimental observations in rats. | Growth hormone (GH) induces growth in animals and humans and also has important metabolic functions. The GH neuroendocrine axis consists of a signaling cascade from the hypothalamus to the pituitary, the liver, and peripheral tissues, including two major feedback mechanisms. GH is secreted from the pituitary into the c... | ['Activity Cycles', 'Animals', 'Computer Simulation', 'Female', 'Growth Hormone', 'Growth Hormone-Releasing Hormone', 'Human Growth Hormone', 'Male', 'Models, Biological', 'Rats', 'Sex Characteristics'] | 9,843,748 | [['G07.180.562.797.500'], ['B01.050'], ['L01.224.160'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['D06.472.699.327.740.860', 'D12.644.400.400.740.860', 'D12.644.548.365.740.860', 'D12.776.631.650.405.740.860'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['E05.599.395'], ['B01.050.150... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Allosteric site-mediated active site inhibition of PBP2a using Quercetin 3-O-rutinoside and its combination. | Recent crystallographic study revealed the involvement of allosteric site in active site inhibition of penicillin binding protein (PBP2a), where one molecule of Ceftaroline (Cef) binds to the allosteric site of PBP2a and paved way for the other molecule (Cef) to bind at the active site. Though Cef has the potency to in... | ['Allosteric Regulation', 'Allosteric Site', 'Anti-Bacterial Agents', 'Binding Sites', 'Catalytic Domain', 'Glucosides', 'Hydrogen Bonding', 'Ligands', 'Microbial Sensitivity Tests', 'Models, Molecular', 'Molecular Conformation', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Penicillin-Binding Prote... | 26,360,629 | [['G02.111.044'], ['G02.111.570.120.147'], ['D27.505.954.122.085'], ['G02.111.570.120'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D09.408.348'], ['G02.282'], ['D27.720.470.480'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E05.599.595'], ['G02.111.570.820'], ['E05.599.595.249',... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The ratio of hormones of system "hypophysis - thyroid" with level of dopamine and cyclic adenosine mono-phosphate of males in European north]. | The study sampling consisted of 96 males from Arkhangelsk and 52 males from village of Nes. The examination was carried out to find out predominant regulative effect of dopamine on the system "hypophysis - thyroid" depending on territory of residence. In males of Zapolyarye, against the background of higher levels of T... | ['Adult', 'Arctic Regions', 'Cyclic AMP', 'Dopamine', 'Humans', 'Male', 'Middle Aged', 'Pituitary Gland', 'Russia', 'Thyroid Gland', 'Thyroid Hormones'] | 25,080,790 | [['M01.060.116'], ['Z01.208'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A06.300.747', 'A06.688.357.750', 'A0... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Diaphyseal bone disease: scintigraphic-radiographic correlation. | Though generally nonspecific, the patterns of diaphyseal uptake of bone seeking radionuclides, when correlated with the radiographic findings and clinical histories, often suggest specific diagnoses and may obviate the need for further imaging. Diaphyseal uptake is considered in terms of "hot spots," unilateral long se... | ['Bone Diseases', 'Bone Neoplasms', 'Humans', 'Radiography', 'Radionuclide Imaging'] | 2,913,616 | [['C05.116'], ['C04.588.149', 'C05.116.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['E01.370.350.710', 'E01.370.384.730']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tissue ascorbic acid, fenfluramine, and changes in fat metabolism. | Following initial weight gain, reduction in appetite and pronounced weight loss occurred in scorbutic unsupplemented guinea-pigs. Hepatic ascorbic acid levels were significantly reduced and cholesterol concentration increased in the liver. Fenfluramine administration caused immediate loss of weight and appetite in the ... | ['Animals', 'Ascorbic Acid', 'Ascorbic Acid Deficiency', 'Body Weight', 'Cholesterol', 'Disease Models, Animal', 'Female', 'Fenfluramine', 'Growth', 'Guinea Pigs', 'Lipid Metabolism', 'Liver', 'Male', 'Obesity', 'Sex Factors', 'Triglycerides'] | 528,124 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A phase II study of combination therapy with irinotecan and S-1 (IRIS) in patients with advanced colorectal cancer. | PURPOSE: A combination of irinotecan with continuous infusional 5-fluorouracil (5-FU) is the standard treatment for advanced colorectal cancer. The aim of this study was to determine the efficacy and safety of combining irinotecan and S-1 (IRIS) in patients with advanced colorectal cancer.METHODS: Irinotecan was admini... | ['Administration, Oral', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Body Surface Area', 'Camptothecin', 'Colorectal Neoplasms', 'Disease-Free Survival', 'Drug Combinations', 'Female', 'Follow-Up Studies', 'Humans', 'Infusions, Intravenous', 'Irinotecan', 'Male', 'Middle Aged', 'Oxonic Acid', 'S... | 20,623,226 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E01.370.600.115.100.231', 'E05.041.124.231', 'G07.100.100.231'], ['D03.132.151'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Osteomyelitis in patients who have sickle-cell disease. Diagnosis and management. | Fifteen patients who had sickle-cell disease and osteomyelitis (affecting thirty bones) were treated with operative decompression and parenteral administration of antibiotics between 1973 and 1988. Organisms were isolated on culture of specimens of bone from all fifteen patients. Parenteral antibiotic therapy was conti... | ['Adult', 'Anemia, Sickle Cell', 'Anti-Bacterial Agents', 'Blood Transfusion', 'Child', 'Female', 'Femur', 'Follow-Up Studies', 'Humans', 'Humerus', 'Infant', 'Male', 'Osteomyelitis', 'Postoperative Complications', 'Salmonella Infections', 'Staphylococcal Infections', 'Tibia'] | 1,918,111 | [['M01.060.116'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['D27.505.954.122.085'], ['E02.095.135'], ['M01.060.406'], ['A02.835.232.043.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Screening instruments for psychiatric morbidity in chronic fatigue syndrome. | Physicians require a screening instrument to detect psychiatric disorders in patients with chronic fatigue syndrome (CFS). Different threshold scores on the Hospital Anxiety and Depression scale (HAD) and the mental health scale of the Medical Outcome Survey (MOS) were compared with two gold standards for the presence ... | ['Adult', 'Anxiety', 'Depression', 'Fatigue Syndrome, Chronic', 'Female', 'Humans', 'Male', 'Mass Screening', 'Mental Disorders', 'Middle Aged', 'Predictive Value of Tests', 'Psychiatric Status Rating Scales', 'Sensitivity and Specificity'] | 9,771,495 | [['M01.060.116'], ['F01.470.132'], ['F01.145.126.350'], ['C01.925.330', 'C05.651.310', 'C10.228.440.600', 'C10.668.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Discordant prolongation of the refractory period and repolarization time by a class III agent, E4031, in the healing phase of myocardial infarction. | Susceptibility to reentrant tachyarrhythmias and the antiarrhythmic efficacy of class III agents are related more to the duration of the refractory period (ERP) than to the repolarization time (RT). We measured both ERP and RT in a canine model of healing myocardial infarction, and evaluated the effect of a class III a... | ['Animals', 'Anti-Arrhythmia Agents', 'Dogs', 'Electrophysiology', 'Female', 'Heart Conduction System', 'Humans', 'Male', 'Myocardial Infarction', 'Piperidines', 'Pyridines', 'Refractory Period, Electrophysiological'] | 9,926,000 | [['B01.050'], ['D27.505.954.411.097'], ['B01.050.150.900.649.313.750.250.216.200'], ['H01.158.344.528', 'H01.158.782.236'], ['A07.541.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['D03.383.621'], ['D03.383.725'], ['G07.265.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication. | The well-known immunosuppressive drug cyclosporin A inhibits replication of various viruses including coronaviruses by binding to cellular cyclophilins thus inactivating their cis-trans peptidyl-prolyl isomerase function. Viral nucleocapsid proteins are inevitable for genome encapsidation and replication. Here we demon... | ['Coronavirus 229E, Human', 'Coronavirus Infections', 'Coronavirus Nucleocapsid Proteins', 'Cyclophilin A', 'Cyclophilins', 'Cyclosporine', 'Host-Pathogen Interactions', 'Humans', 'Nucleocapsid Proteins', 'Protein Binding', 'Virus Replication'] | 31,634,494 | [['B04.820.578.500.540.150.075.750'], ['C01.925.782.600.550.200'], ['D12.776.964.970.600.700'], ['D08.811.399.325.500.400.300.500'], ['D08.811.399.325.500.400.300', 'D12.776.543.750.705.400.300', 'D12.776.827.275.300'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subretinal lesions following a scleral buckling procedure. | Pigment epithelial detachment is usually associated with disorders of the underlying Bruch's membrane and choroid in a context of age-related macular degeneration. In a very few cases, lesions resembling pigment epithelial detachment have been reported after retinal reattachment surgery. We observed an additional case ... | ['Female', 'Fluorescein Angiography', 'Follow-Up Studies', 'Fundus Oculi', 'Humans', 'Middle Aged', 'Pigment Epithelium of Eye', 'Retina', 'Retinal Detachment', 'Retinal Diseases', 'Scleral Buckling', 'Visual Acuity'] | 9,097,319 | [['E01.370.370.050.350', 'E01.370.380.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A09.371.670', 'A10.272.640'], ['A09.371.729'], ['C11.768.648'], ['C11.768'], ['E04.540.890'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extracorporeal life support for posttraumatic acute respiratory distress syndrome at a children's medical center. | BACKGROUND: Primary traumatic injury was considered previously a contraindication for institution of extracorporeal life support because of high risk for persistent or new bleeding. Published experience in adults suggests that extracorporeal membrane oxygenation (ECMO) can successfully support trauma victims with pulmo... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Extracorporeal Membrane Oxygenation', 'Female', 'Hemorrhage', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Liver', 'Male', 'Respiratory Distress Syndrome', 'Spleen', 'Treatment Outcome', 'Wounds and Injuries'] | 12,891,497 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E02.880.301', 'E04.292.451'], ['C23.550.414'], ['N02.278.421.556.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A03.620'], ['C08.381.840', 'C08.618.840'], ['A10.549.700', 'A15.382.520.604.700'], ['E01.789.800', 'N04.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Examining cross-database global training to evaluate five different methods for ventricular beat classification. | The detection of ventricular beats in the holter recording is a task of great importance since it can direct clinicians toward the parts of the electrocardiogram record that might be crucial for determining the final diagnosis. Although there already exists a fair amount of research work dealing with ventricular beat d... | ['Algorithms', 'Arrhythmias, Cardiac', 'Databases as Topic', 'Electrocardiography, Ambulatory', 'Heart Ventricles', 'Humans', 'Sensitivity and Specificity'] | 19,525,571 | [['G17.035', 'L01.224.050'], ['C14.280.067', 'C23.550.073'], ['L01.313.500.750.300.188', 'L01.470.750'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Isolation and characterization of a quinclorac-degrading Actinobacteria Streptomyces sp. strain AH-B and its implication on microecology in contaminated soil. | Quinclorac, a highly selective auxin herbicide, is widely used for controlling weeds in rice field. However, the residual quinclorac is toxic to many crops, vegetables, and aquatic animals, resulting in one of the major problems in crop rotation. Here, we investigated the degradation of quinclorac by strain AH-B, which... | ['Basidiomycota', 'Biodegradation, Environmental', 'China', 'Herbicides', 'Oryza', 'Phylogeny', 'Quinolines', 'RNA, Ribosomal, 16S', 'Soil', 'Soil Microbiology', 'Soil Pollutants', 'Streptomyces'] | 29,438,948 | [['B01.300.179'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['Z01.252.474.164'], ['D27.720.031.700.366', 'D27.888.723.366'], ['B01.650.940.800.575.912.250.822.616'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D03.633.100.810'], ['D13.444.735.686.670'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'... | ['Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Dopamine markers and general cognitive ability. | Because general cognitive ability (g) is among the most heritable behavioural traits, it is a reasonable target for a search for quantitative trait loci (QTLs). We used a selected-extremes design to test candidate genes for allelic association with g. Polymorphisms in four genes in the dopamine system (DRD2, DRD3, DRD4... | ['Adolescent', 'Alleles', 'Biomarkers', 'Child', 'Cognition', 'DNA', 'Dopamine', 'Female', 'Genotype', 'Humans', 'Intelligence Tests', 'Male', 'Polymorphism, Genetic', 'Quantitative Trait, Heritable'] | 9,507,981 | [['M01.060.057'], ['G05.360.340.024.340.030'], ['D23.101'], ['M01.060.406'], ['F02.463.188'], ['D13.444.308'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.141.493'], ['G05.365.795'], ['G05.420.720']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Postnatal changes in the reticular lamina of the guinea pig organ of Corti. | The dimensions of the apical surfaces of hair cells were measured in guinea pigs, aged from 3 weeks before term to 25 weeks after birth. In the basal two-thirds of the cochlea, the apical surfaces of the outer hair cells and their supporting cells changed with age, shrinking in a direction radial across the cochlear du... | ['Aging', 'Animals', 'Animals, Newborn', 'Guinea Pigs', 'Hair Cells, Auditory, Outer', 'Labyrinth Supporting Cells', 'Microscopy, Electron, Scanning', 'Organ of Corti', 'Tissue Fixation'] | 8,922,978 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.992.550'], ['A08.675.650.250.315', 'A08.675.650.915.750.600.350.365', 'A08.800.950.750.600.350.365', 'A09.246.300.246.577.325.380', 'A11.671.650.250.315', 'A11.671.650.915.750.600.350.365'], ['A09.246.300.246.577.543', 'A11.436.495'], ['E01.3... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Anesthesia in coronary disease]. | Patients undergoing non-cardiac surgery and who have coronary artery disease run a high risk of myocardial infarct. Diagnosis and postoperative management is presently based on assessment of cardiac troponin I. Associated with optimal postoperatory management, several approaches can limit the occurrence of postoperator... | ['Adrenergic beta-Antagonists', 'Anesthesia, General', 'Anti-Inflammatory Agents, Non-Steroidal', 'Coronary Disease', 'Humans', 'Life Expectancy', 'Myocardial Infarction', 'Myocardial Revascularization', 'Postoperative Complications', 'Surgical Procedures, Operative'] | 11,387,688 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['E03.155.197'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.450', 'N01.224.935.464', 'N06.850.505.400.975.45... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma. | Approximately 80% of patients with pancreatic ductal adenocarcinoma (PDAC) have metastatic disease with poor prognosis, but clinically available biomarkers have not yet been identified. This study was to investigate the clinical significance of FZD1 and CAIX in PDACs. FZD1 and CAIX protein expression was measured using... | ['Adult', 'Aged', 'Antigens, Neoplasm', 'Biomarkers, Tumor', 'Carbonic Anhydrase IX', 'Carcinoma, Pancreatic Ductal', 'Disease Progression', 'Female', 'Frizzled Receptors', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Pancreatic Neoplasms', 'Prognosis'] | 28,921,449 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.285'], ['D23.101.140'], ['D08.811.520.241.300.150.450', 'D12.776.543.178', 'D23.050.285.196'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.625', 'C19.344.421.750'], ['C23.550.291... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Is breast cancer screening effective? (author's transl)]. | Two groups of patients consisting of women with and without breast symptoms are compared. They were mammographed in the same institute under identical technical conditions. Carcinomas found by screening were considerably less advanced. The findings confirm the experience of numerous authors that screening improves the ... | ['Breast Neoplasms', 'Cost-Benefit Analysis', 'Female', 'Humans', 'Lymphatic Metastasis', 'Mammography', 'Mass Screening', 'Prognosis'] | 120,634 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human Performance in a Realistic Instrument-Control Task during Short-Term Microgravity. | Previous studies have documented the detrimental effects of microgravity on human sensorimotor skills. While that work dealt with simple, laboratory-type skills, we now evaluate the effects of microgravity on a complex, realistic instrument-control skill. Twelve participants controlled a simulated power plant during th... | ['Adult', 'Biomechanical Phenomena', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Motor Activity', 'Task Performance and Analysis', 'Weightlessness', 'Workload'] | 26,083,473 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['F01.145.632', 'G11.427.410.698'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['G01.060.350.369.400.900'], ['I03.946.225.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Regional climate shifts caused by gradual global cooling in the Pliocene epoch. | The Earth's climate has undergone a global transition over the past four million years, from warm conditions with global surface temperatures about 3 degrees C warmer than today, smaller ice sheets and higher sea levels to the current cooler conditions. Tectonic changes and their influence on ocean heat transport have ... | ['Animals', 'Calcium Carbonate', 'Climate', 'Cold Temperature', 'Geologic Sediments', 'Hot Temperature', 'Ice', 'Oxygen Isotopes', 'Pacific Ocean', 'Seawater', 'Time Factors', 'Tropical Climate'] | 15,152,244 | [['B01.050'], ['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.311.330', 'G16.500.320'], ['G01.906.595.543', 'G16.500.275.063.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis. | PURPOSE: To identify genes that modify metastatic risk in uveal melanoma, a type of cancer that is valuable for studying metastasis because of its remarkably consistent metastatic pattern and well-characterized gene expression signature associated with metastasis.EXPERIMENTAL DESIGN: We analyzed 53 primary uveal melano... | ['Cell Adhesion', 'Cell Movement', 'Chromosomes, Human, Pair 8', 'Cluster Analysis', 'Cohort Studies', 'DNA Methylation', 'DNA-Binding Proteins', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Genes, Tumor Suppressor', 'Genomics', 'Humans', 'Melanoma', 'Neoplasm Metastasis', 'Oligonucleotide Ar... | 18,559,591 | [['G04.022'], ['G04.198', 'G07.568.500.180'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.2... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A comparative assessment of changes in dental arches associated with different activation protocols of rapid maxillary expansion. | AIM: The aim of this study is to compare dental arch changes associated with different activation protocols of maxillary expander.MATERIALS AND METHODS: A sample of 101 subjects with constricted maxillary arches (49 males and 52 females; mean age 10.96 ± 1.91 years) was enrolled in the study. All subjects underwent RME... | ['Case-Control Studies', 'Child', 'Dental Arch', 'Female', 'Humans', 'Jaw Relation Record', 'Male', 'Palatal Expansion Technique'] | 29,569,451 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['A02.835.232.781.324.502.320', 'A14.521.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.520'], ['E06.658.578.458']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Negative first-term outcomes associated with lower extremity injury during recruit training among female Marine Corps graduates. | This study assessed the impact of lower extremity injuries and stress fractures during recruit training on first-term outcomes among female Marine Corps graduates. Injury data were collected from women recruits at Parris Island, South Carolina (1995-1999) and negative first-term outcomes were obtained from the Career H... | ['Adult', 'Career Mobility', 'Female', 'Humans', 'Leg Injuries', 'Military Medicine', 'Military Personnel', 'Personnel Turnover', 'Physical Education and Training', 'Prospective Studies', 'United States'] | 17,274,273 | [['M01.060.116'], ['N01.824.245.175', 'N01.824.547.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['H02.403.500'], ['M01.526.625'], ['N04.452.677.680'], ['I02.233.543'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Activated production of metalloproteinases in Ki-ras-transformed human osteosarcoma cells. | The human osteosarcoma cell culture HOS does not produce matrix metalloproteinases (MPs). However, after transformation with the Ki-ras oncogene, the resulting culture (KHOS) produced readily detectable MPs. The molecular weight of the major MP was 66 kDa, while the molecular weights of two other minor bands were 71 kD... | ['Genes, ras', 'Humans', 'Metalloendopeptidases', 'Osteosarcoma', 'Phenylmercuric Acetate', 'Tretinoin', 'Tumor Cells, Cultured'] | 8,152,301 | [['G05.360.340.024.340.375.500.791.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480', 'D08.811.277.656.675.374'], ['C04.557.450.565.575.650', 'C04.557.450.795.620'], ['D02.691.750.740.760'], ['D02.455.326.271.665.202.495.818.500', 'D02.455.426.392.368.367.379.249.700.860.500', 'D02.455.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proteins associated with the termination of ocular dominance column plasticity in Long Evans rats. | PURPOSE: To investigate the mechanism of the termination of ocular dominance column plasticity by electrophysiologic analysis and 2-dimensional electrophoresis-mass spectrography (2-DE/MS).METHODS: The changes in ocular dominance columns following monocular deprivation were electrophysiologically detected in 22-day-old... | ['Animals', 'Dominance, Ocular', 'Glial Fibrillary Acidic Protein', 'Neuronal Plasticity', 'Phosphatidylethanolamine Binding Protein', 'Rats', 'Rats, Long-Evans', 'Visual Cortex'] | 18,041,181 | [['B01.050'], ['G11.561.225.425.500', 'G14.264'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['G11.561.638'], ['D12.644.360.562', 'D12.776.157.661', 'D12.776.476.555'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.500'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photoacoustic diagnosis of burns in rats. | BACKGROUND: Accurate burn depth assessment is important for determining the appropriate treatment plan for severe burn patients. However, conventional methods of diagnoses, such as visual observation and pinprick test, are often inaccurate. We previously proposed a new method for burn diagnosis in which photoacoustic s... | ['Acoustics', 'Animals', 'Burns', 'Disease Models, Animal', 'Luminescence', 'Male', 'Photic Stimulation', 'Rats', 'Rats, Wistar', 'Reproducibility of Results', 'Signal Processing, Computer-Assisted', 'Transducers'] | 16,394,921 | [['H01.671.031'], ['B01.050'], ['C26.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E05.723.729'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['E05.318.370.725', 'E05... | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Electroacupuncture Exerts Neuroprotection through Caveolin-1 Mediated Molecular Pathway in Intracerebral Hemorrhage of Rats. | Spontaneous intracerebral hemorrhage (ICH) is one of the most devastating types of stroke. Here, we aim to demonstrate that electroacupuncture on Baihui (GV20) exerts neuroprotection for acute ICH possibly via the caveolin-1/matrix metalloproteinase/blood-brain barrier permeability pathway. The model of ICH was establi... | ['Animals', 'Blood-Brain Barrier', 'Caveolin 1', 'Cerebral Hemorrhage', 'Electroacupuncture', 'Male', 'Neuroprotective Agents', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Signal Transduction'] | 27,725,888 | [['B01.050'], ['A07.035', 'A08.186.211.035'], ['D12.644.360.024.264', 'D12.776.157.057.010', 'D12.776.476.024.280', 'D12.776.543.990.100.500', 'D12.776.744.287'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['E02.186.250', 'E02.190.044.244', 'E02.331.399', 'E02.779.468.399', 'E02.831.535.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Body image and sexuality in women with pelvic organ prolapse. | INTRODUCTION: The effect of physical changes associated with pelvic organ prolapse on a woman's body image and how that may influence sexuality has not been well studied.OBJECTIVE: The goal of this study was to assess the implementation and utility of a body image questionnaire in women with pelvic organ prolapse. Two ... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Body Image', 'Cystocele', 'Female', 'Humans', 'Michigan', 'Middle Aged', 'Nursing Assessment', 'Nursing Methodology Research', 'Qualitative Research', 'Rectocele', 'Severity of Illness Index', 'Sexual Partners', 'Sexuality', 'Sha... | 19,718,939 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['F01.752.747.792.110', 'F02.463.593.112'], ['C12.777.829.707', 'C13.351.968.829.508', 'C23.300.842.624.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.500', 'Z01.107.567.875.510.50... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Reconstructing an island radiation using ancient and recent DNA: the extinct and living day geckos (Phelsuma) of the Mascarene islands. | Mitochondrial (12SrRNA and cyt b, 1086 bp) and nuclear (c-mos, 374 bp) DNA sequences were used to investigate relationships and biogeography of 24 living and extinct taxa of Phelsuma geckos. Monophyly of Phelsuma and sister relationship to the SW African Rhoptropella is corroborated. Phelsuma originated on Madagascar a... | ['Animals', 'Cytochromes b', 'DNA, Mitochondrial', 'Fossils', 'Genes, mos', 'Indian Ocean Islands', 'Lizards', 'Mauritius', 'Phylogeny', 'RNA, Ribosomal'] | 15,019,612 | [['B01.050'], ['D08.244.187.249', 'D12.776.422.220.187.249'], ['D13.444.308.283.225'], ['I01.076.368.584.311'], ['G05.360.340.024.340.375.500.791.400'], ['Z01.639.520'], ['B01.050.150.900.833.393'], ['Z01.639.520.520'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
Shoot or don't shoot? Why police officers are more inclined to shoot when they are anxious. | We investigated the effect of anxiety on police officers' shooting decisions. Thirty-six police officers participated and executed a low- and high-anxiety video-based test that required them to shoot or not shoot at rapidly appearing suspects that either had a gun and "shot," or had no gun and "surrendered." Anxiety wa... | ['Adult', 'Anxiety', 'Decision Making', 'Eye Movements', 'Fear', 'Female', 'Firearms', 'Humans', 'Male', 'Police', 'Video Recording', 'Visual Perception'] | 22,023,363 | [['M01.060.116'], ['F01.470.132'], ['F02.463.785.373'], ['G11.427.410.140', 'G14.350'], ['F01.470.361'], ['J01.637.870.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.373.750', 'M01.526.760'], ['L01.280.960'], ['F02.463.593.932']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Dual atrioventricular nodal non-reentrant tachycardia in a child undergoing repair of ventricular septal defect. | Paroxysmal non-reentrant supraventricular tachycardia due to double ventricular response through antegrade dual atrioventricular nodal pathways by a single atrial excitation has been reported in limited adult cases but not in pediatric patients with structurally normal hearts or with congenital heart defects. We report... | ['Body Surface Potential Mapping', 'Cardiac Surgical Procedures', 'Catheter Ablation', 'Child, Preschool', 'Echocardiography, Doppler', 'Electrocardiography', 'Follow-Up Studies', 'Heart Septal Defects, Ventricular', 'Humans', 'Male', 'Postoperative Care', 'Postoperative Complications', 'Risk Assessment', 'Severity of ... | 22,555,890 | [['E01.370.370.380.240.850.100', 'E01.370.405.240.850.100'], ['E04.100.376', 'E04.928.220'], ['E02.808.750.500', 'E04.014.760.500'], ['M01.060.406.448'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.37... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endovascular trophoblast invasion, spiral artery remodelling and uteroplacental haemodynamics in a transgenic rat model of pre-eclampsia. | The aim of the present study was to evaluate the depth of endovascular trophoblast invasion and associated remodelling of spiral arteries in a transgenic model of pre-eclampsia in the rat, a species showing a comparable deep invasion during normal pregnancy as the human. Pre-eclamptic (PE) transgenic rats (TGR) (hAngio... | ['Angiotensinogen', 'Animals', 'Animals, Genetically Modified', 'Arteries', 'Cell Adhesion', 'Disease Models, Animal', 'Endothelium, Vascular', 'Female', 'Hemodynamics', 'Male', 'Placental Circulation', 'Pre-Eclampsia', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Renin', 'Trophoblasts', 'Uterus'] | 18,502,502 | [['D12.644.456.073.070', 'D12.644.861.020', 'D12.776.811.070', 'D12.776.872.020'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['A07.015.114'], ['G04.022'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A07.015.700.500', 'A10.272.491.355'], ['G09.330.380'], ['G09.330.100.749'], ['C13.703.395.249'], ['G08.686.78... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo effects of diadenosine polyphosphates on rat renal microcirculation. | BACKGROUND: Diadenosine polyphosphates (APXA) are vasoactive nucleotides that elicit effects via purinoceptors. Recent data suggest differential effects of APXA on kidney vasculature.METHODS: The in vivo effects of AP3A, AP5A, and adenosine on renal microvessels and the role of purinoceptors were investigated by the ap... | ['Adenosine', 'Animals', 'Arterioles', 'Blood Vessels', 'Dinucleoside Phosphates', 'Female', 'Hydronephrosis', 'Microcirculation', 'Rats', 'Rats, Wistar', 'Receptors, Purinergic P1', 'Receptors, Purinergic P2', 'Renal Artery', 'Renal Circulation', 'Vasoconstriction', 'Vasomotor System'] | 10,844,616 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['A07.015.114.060', 'A07.015.461.080'], ['A07.015'], ['D13.695.250'], ['C12.777.419.307', 'C13.351.968.419.307'], ['G09.330.100.645'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D12.776.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adjuvant effect of low-dose interleukin-2 on antibody response to influenza virus vaccination in healthy elderly subjects. | It is well known that immune efficiency is frequently deteriorated in elderly people. The age-diminished antibody response to T-cell dependent antigens, such as influenza virus antigens, may explain the low protection offered by influenza vaccination in the elderly population. To investigate the possibility of increasi... | ['Adjuvants, Immunologic', 'Aged', 'Aged, 80 and over', 'Antibody Formation', 'Case-Control Studies', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Influenza Vaccines', 'Interleukin-2', 'Male', 'Middle Aged', 'Orthomyxoviridae', 'Reference Values'] | 7,745,993 | [['D27.505.696.477.067'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G12.450.050.370.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['D12.644.276.374.465.021', 'D... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Morphologic changes of peritoneum and expression of VEGF in encapsulated peritoneal sclerosis rat models. | BACKGROUND: Simple sclerosis consisted of a thin layer of submesothelial sclerotic tissue in peritoneal dialysis patients. Encapsulated peritoneal sclerosis (EPS) was characterized by thick sclerotic tissue involving vascular alterations in peritoneal dialysis patients. The objective of the present study is to evaluate... | ['Angiopoietin-1', 'Angiopoietin-2', 'Animals', 'Base Sequence', 'Chlorhexidine', 'DNA', 'Gene Expression', 'Immunohistochemistry', 'Male', 'Neovascularization, Pathologic', 'Peritoneal Dialysis', 'Peritoneum', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Vascular Endothelial Growth Factor', 'Sclerosis... | 15,086,936 | [['D12.644.276.100.100.100', 'D12.776.467.100.100.100', 'D23.529.100.100.100'], ['D12.644.276.100.100.200', 'D12.776.467.100.100.200', 'D23.529.100.100.200'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.078.370.141.100'], ['D13.444.308'], ['G05.297'], ['E01.370.225.500.607.512', 'E01.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
p150Glued, the largest subunit of the dynactin complex, is nonessential in Neurospora but required for nuclear distribution. | Dynactin is a multisubunit complex that is required for cytoplasmic dynein, a minus-end-directed, microtubule-associated motor, to efficiently transport vesicles along microtubules in vitro. p150Glued, the largest subunit of dynactin, has been identified in vertebrates and Drosophila and recently has been shown to inte... | ['Actins', 'Amino Acid Sequence', 'Base Sequence', 'Cell Survival', 'Cloning, Molecular', 'Dynactin Complex', 'Dyneins', 'Genes, Fungal', 'Genetic Complementation Test', 'Immunohistochemistry', 'Microtubule Proteins', 'Microtubule-Associated Proteins', 'Microtubules', 'Molecular Sequence Data', 'Neurospora crassa', 'Po... | 8,744,947 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.346'], ['E05.393.220'], ['D05.500.142', 'D12.776.220.600.450.150', 'D12.776.631.560.225'], ['D08.811.277.040.013.500.063', 'D08.811.277.040... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Conscious intention and motor cognition. | The subjective experience of conscious intention is a key component of our mental life. Philosophers studying 'conscious free will' have discussed whether conscious intentions could cause actions, but modern neuroscience rejects this idea of mind-body causation. Instead, recent findings suggest that the conscious exper... | ['Brain', 'Cognition', 'Consciousness', 'Humans', 'Intention', 'Magnetics', 'Motion Perception', 'Movement', 'Neurons'] | 15,925,808 | [['A08.186.211'], ['F02.463.188'], ['F02.463.188.409', 'F02.830.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['H01.671.493'], ['F02.463.593.932.567'], ['G07.568', 'G11.427.410'], ['A08.675', 'A11.671']] | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
BM-BC: a Bayesian method of base calling for Solexa sequence data. | Base calling is a critical step in the Solexa next-generation sequencing procedure. It compares the position-specific intensity measurements that reflect the signal strength of four possible bases (A, C, G, T) at each genomic position, and outputs estimates of the true sequences for short reads of DNA or RNA. We presen... | ['Algorithms', 'Bayes Theorem', 'Genome', 'Genomics', 'RNA', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Software'] | 23,320,938 | [['G17.035', 'L01.224.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G05.360.340'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['D13.444.735'], ['E05.393.751'], ['E05.393.760.700'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Prostaglandin endoperoxide-H synthase-1 and -2 messenger ribonucleic acid levels in human amnion with spontaneous labor onset. | Increased prostaglandin (PG) production within the uterine compartment has a pivotal role in the processes leading to labor onset in women. Two PG endoperoxide-H synthase (PGHS) isoenzymes have been identified in a number of cell types. PGHS-1 is constitutively expressed in most cases, whereas PGHS-2 expression is rapi... | ['Amnion', 'Blotting, Northern', 'Female', 'Humans', 'Labor Onset', 'Pregnancy', 'Prostaglandin-Endoperoxide Synthases', 'RNA, Messenger'] | 7,852,513 | [['A10.615.284.277', 'A16.254.750.277'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326.500'], ['G08.686.784.769'], ['D08.811.600.720', 'D08.811.682.690.708.715'], ['D13.444.735.544']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Continuous circular capsulorhexis and nucleus delivery in planned extracapsular cataract extraction. | A technique for nucleus delivery through a continuous circular capsulorhexis in planned extracapsular cataract extraction is presented. The concept of hydro- and viscoexpression of the nucleus is explained, and a strongly bent cannula specially designed for the procedure is introduced. | ['Cataract Extraction', 'Equipment Design', 'Humans', 'Lens Nucleus, Crystalline'] | 1,941,599 | [['E04.540.825.249'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.500.670']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat. | While altered activities in sensory neurons were noticed in neuropathic pain, caused by highly diverse insults to the peripheral nervous system, such as diabetes, alcohol ingestion, cancer chemotherapy and drugs used to treat AIDS, other infections and autoimmune diseases, as well as trauma, our understanding of how th... | ['Acquired Immunodeficiency Syndrome', 'Alcoholic Neuropathy', 'Animals', 'Comorbidity', 'Disease Models, Animal', 'Ethanol', 'Mechanics', 'Mechanotransduction, Cellular', 'Nerve Fibers, Unmyelinated', 'Pain', 'Peripheral Nervous System Diseases', 'Rats', 'Zalcitabine'] | 17,319,957 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['C10.668.829.800.050', 'C10.720.112.400', 'C25.723.705.150.400', 'C25.775.100.087.193.400'], ['B01.050'], ['N05.715.350.225', 'N06.850.490.687'], ['C22... | ['Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Intraperitoneal cisplatin plus intravenous cyclophosphamide versus intravenous cisplatin plus intravenous cyclophosphamide for stage III ovarian cancer. | BACKGROUND: Intravenous platinum-based chemotherapy is the standard primary therapy for advanced ovarian cancer. We conducted a phase 3 trial to compare the effects of intraperitoneal and intravenous cisplatin on the survival of women with previously untreated, stage III, epithelial ovarian cancer.METHODS: The patients... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma', 'Cisplatin', 'Cyclophosphamide', 'Female', 'Hearing Disorders', 'Humans', 'Infusions, Intravenous', 'Infusions, Parenteral', 'Leukopenia', 'Middle Aged', 'Neoplasm Staging', 'Ovarian Neoplasms', 'Survival Analysis'] | 8,960,474 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tissue distribution and subcellular localization of rabbit liver metalloendopeptidase. | We have previously isolated rabbit liver microsomal metalloendopeptidase (MEP) as a candidate for the processing enzyme of vitamin K-dependent plasma proteins. A cDNA coding for MEP has revealed that it is structurally related to metalloendopeptidase-24.15, which catalyzes the proteolytic processing of several bioactiv... | ['Amino Acid Sequence', 'Animals', 'Blotting, Northern', 'Brain', 'Cell Membrane', 'Cytoplasm', 'Duodenum', 'Female', 'Immunoenzyme Techniques', 'Kidney', 'Liver', 'Lung', 'Male', 'Metalloendopeptidases', 'Microscopy, Immunoelectron', 'Microsomes, Liver', 'Molecular Sequence Data', 'RNA, Messenger', 'Rabbits', 'Stomach... | 9,010,467 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A08.186.211'], ['A11.284.149'], ['A11.284.430.214'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A05.810.453'], ['A03.620'], ['A04.411'], ['D08.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The isolation, mapping and transcription in vitro of a beta 0-thalassaemia globin gene. | The red blood cell precursors of a patient with homozygous beta 0-thalassaemia have previously been shown to contain nuclear, but not cytoplasmic, beta-globin-specific transcripts. We describe the isolation of a beta-globin gene from this patient as a recombinant bacteriophage chromosome. Restriction-enzyme cleavage-si... | ['Base Sequence', 'Cloning, Molecular', 'DNA', 'DNA Restriction Enzymes', 'Globins', 'Humans', 'In Vitro Techniques', 'Nucleic Acid Hybridization', 'Spleen', 'Thalassemia', 'Transcription, Genetic'] | 6,276,172 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D12.776.422.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E05.393.661', 'G02.111.611'], ['A10.549.700', 'A15.382.520... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.