Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[A comparative statistical study of the background impulse activity of hippocampal neurons in situ and in tissue culture]. | Statistical characteristics of background impulse activity of the rat hippocampal pyramidal neurons in situ and in vitro were compared. A statistical analysis shows a good coincidence of the following numerical characteristics of interspike intervals distribution: mathematical expectations, standard deviations, coeffic... | ['Animals', 'Culture Techniques', 'Electrophysiology', 'Female', 'Hippocampus', 'Male', 'Rats'] | 1,207,817 | [['B01.050'], ['E05.481.500'], ['H01.158.344.528', 'H01.158.782.236'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Direct Reprogramming of Human Amniotic Fluid Stem Cells by OCT4 and Application in Repairing of Cerebral Ischemia Damage. | Amniotic fluid stem cells (AFSCs) are a type of fetal stem cell whose stemness encompasses both embryonic and adult stem cells, suggesting that they may be easily and efficiently reprogrammed into induced pluripotent stem cells (iPSCs). To further simplify the reprogramming process, the creation of AFSC-derived iPSCs u... | ['Amniotic Fluid', 'Animals', 'Brain Ischemia', 'Cell Differentiation', 'Cells, Cultured', 'Cellular Reprogramming', 'Embryonic Stem Cells', 'Humans', 'Induced Pluripotent Stem Cells', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Octamer Transcription Factor-3', 'Pluripotent Stem Cells', 'Rats', 'Rats, Wistar'] | 27,019,637 | [['A12.098', 'A16.378.149'], ['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G04.152'], ['A11.251'], ['G04.152.262', 'G05.135'], ['A11.872.700.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Specificity of subnormal deltaPO2 for retinal neovascularization in experimental retinopathy of prematurity. | PURPOSE: To test the hypothesis that in an experimental model of retinopathy of prematurity (ROP) rat pups that are at risk for but do not have retinal neovascularization (NV) exhibit a normal oxygenation response to a hyperoxic inhalation challenge.METHODS: Newborn Sprague-Dawley rats were raised under two varied oxyg... | ['Animals', 'Animals, Newborn', 'Carbon Dioxide', 'Disease Models, Animal', 'Female', 'Humans', 'Hyperoxia', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Oxygen', 'Oxygen Consumption', 'Rats', 'Rats, Sprague-Dawley', 'Retina', 'Retinal Neovascularization', 'Retinopathy of Prematurity'] | 12,882,806 | [['B01.050'], ['B01.050.050.282'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.567'], ['M01.060.703.520'], ['E01.370.350.825.500'], ['D01.268.185.550', 'D01.362.670'], ['G03.680'], ['B01.050.150.900.649.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Closing loopholes in the Biological Weapons Convention. | The Biological and Toxin Weapons Convention (BTWC) received two major blows in the past months. Negotiations for a protocol to strengthen the BTWC came to a halt and the Fifth Review Conference was unable to reach agreement on a final declaration. In addition, ongoing research projects, predominantly in the United Stat... | ['Biological Warfare', 'Congresses as Topic', 'Humans', 'International Agencies', 'International Cooperation', 'Terminology as Topic'] | 12,044,027 | [['I01.880.735.950.500.226'], ['N03.540.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.514'], ['I01.615.500'], ['L01.559.598.400']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Interpersonal conflicts at work and psychosocial characteristics of employees. | Associations of psychosocial factors with interpersonal conflicts at work were studied in a sample drawn from the Finnish population using a mailed questionnaire. The sample consisted of 14,578 employees aged 24-64 years. The frequency of interpersonal conflicts at work was equal among both sexes. Our results suggest t... | ['Adult', 'Conflict, Psychological', 'Cross-Sectional Studies', 'Female', 'Finland', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Occupational Diseases', 'Personal Satisfaction', 'Risk Factors', 'Self Concept', 'Stress, Psychological'] | 2,047,897 | [['M01.060.116'], ['F01.658.209'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['C24'], ['F01.145.677'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Large scale analysis of protein-binding cavities using self-organizing maps and wavelet-based surface patches to describe functional properties, selectivity discrimination, and putative cross-reactivity. | A new method to discover similar substructures in protein binding pockets, independently of sequence and folding patterns or secondary structure elements, is introduced. The solvent-accessible surface of a binding pocket, automatically detected as a depression on the protein surface, is divided into a set of surface pa... | ['Algorithms', 'Binding Sites', 'Databases, Protein', 'Neural Networks, Computer', 'Protein Binding', 'Protein Structure, Secondary', 'Proteins', 'Surface Properties'] | 18,041,748 | [['G17.035', 'L01.224.050'], ['G02.111.570.120'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['G17.485', 'L01.224.050.375.605'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.600'], ['D12.776'], ['G02.860']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
RESOLUTION OF A MACULAR HOLE COMPLICATING A PSEUDOPHAKIC MACULAR EDEMA WITH NONSURGICAL TREATMENT. | BACKGROUND: Pseudophakic cystoid macular edema (PCME) is a common complication of cataract surgery. We report the management of a case presenting with PCME in his left eye complicated by a full-thickness macular hole (MH). Four weeks after a cataract surgery on his left eye, a 75-year-old man presented with a vision lo... | ['Acetazolamide', 'Administration, Oral', 'Aged', 'Conservative Treatment', 'Diuretics', 'Dose-Response Relationship, Drug', 'Fluorescein Angiography', 'Follow-Up Studies', 'Fundus Oculi', 'Humans', 'Macular Edema', 'Male', 'Pseudophakia', 'Recovery of Function', 'Retinal Perforations', 'Tomography, Optical Coherence',... | 27,787,409 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['E02.319.267.100'], ['M01.060.116.100'], ['E02.197'], ['D27.505.696.560.500'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.370.050.350', 'E01.370.380.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A09.371.72... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inference by exclusion in the red-tailed black cockatoo (Calyptorhynchus banksii). | Inference by exclusion is the ability to select a given option by excluding the others. When designed appropriately, tests of this ability can reveal choices that cannot be explained by associative processes. Over the past decade, exclusion reasoning has been explored in several non-human taxonomic groups, including bi... | ['Animals', 'Choice Behavior', 'Cockatoos', 'Discrimination, Psychological', 'Female', 'Male', 'Psychomotor Performance'] | 29,316,266 | [['B01.050'], ['F02.463.785.373.346'], ['B01.050.150.900.248.710.251'], ['F02.463.593.257'], ['F02.808', 'G11.427.700', 'G11.561.660']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Historical and contemporary correlates of syphilis and cancer. | BACKGROUND: This study examined the relationship between antecedent syphilis infection and cancer incidence in an attempt to identify specific cancer patterns.METHODS: The study cohort consisted of 16,420 people diagnosed with syphilis between 1972 and 1987 and who were residents of New York State, exclusive of New Yor... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Causality', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Neoplasms', 'New York', 'Risk Factors', 'Sarcoma, Kaposi', 'Syphilis', 'Tongue Neoplasms'] | 8,082,966 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.200', 'N06.850.490.625'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evaluation of patients with lactic acidosis using microphotometric mitochondrial enzyme assay in single muscle fibers. | Microphotometric enzyme assay in single muscle fibers was performed on two patients with lactic acidosis. Neither case showed ragged red fibers upon histochemical evaluation. Biochemical analysis of mitochondrial enzymes demonstrated low normal cytochrome c oxidase (COX) activity in Case 1 and deficient COX in Case 2. ... | ['Acidosis, Lactic', 'Adolescent', 'Child, Preschool', 'Cytochrome-c Oxidase Deficiency', 'Electron Transport Complex IV', 'Female', 'Histocytochemistry', 'Humans', 'Infant', 'Male', 'Mitochondria, Muscle', 'Muscle Fibers, Skeletal', 'Photometry', 'Succinate Dehydrogenase'] | 7,818,028 | [['C18.452.076.176.180'], ['M01.060.057'], ['M01.060.406.448'], ['C16.320.565.240', 'C18.452.660.195'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Stakeholder perspectives on addressing adverse events from adjuvant cancer therapy: A qualitative study. | BACKGROUND: With increasing survival rates, a growing population of patients with cancer have received or will receive adjuvant therapy to prevent cancer recurrences. Patients and caregivers will confront the complexities of balancing the preventative benefits of adjuvant therapy with possible near-term or long-term ad... | ['Caregivers', 'Chemotherapy, Adjuvant', 'Health Care Surveys', 'Health Personnel', 'Humans', 'Neoplasms', 'Physicians', 'Qualitative Research'] | 31,454,424 | [['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E02.186.170', 'E02.319.170'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['M01.526.485.810', 'N02.360.810'], ['H01... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of co- and sequential inoculation of Torulaspora delbrueckii and Pichia kluyveri on chemical compositions of durian wine. | This is a first study on using two non-Saccharomyces yeasts, Torulaspora delbrueckii Biodiva and Pichia kluyveri FrootZen to produce durian wine via co-inoculation (Co-I) and sequential inoculation (Seq-I). T. delbrueckii inhibited the growth of P. kluyveri and P. kluyveri also partly retarded the growth of T. delbruec... | ['Acetates', 'Bombacaceae', 'Ethanol', 'Malates', 'Microbial Interactions', 'Pichia', 'Succinic Acid', 'Torulaspora', 'Wine'] | 28,942,463 | [['D02.241.081.018', 'D10.251.400.045'], ['B01.650.940.800.575.912.250.148'], ['D02.033.375'], ['D02.241.081.337.463', 'D02.241.511.505'], ['G06.550'], ['B01.300.107.795.700', 'B01.300.930.600'], ['D02.241.081.337.759.625'], ['B01.300.107.795.830', 'B01.300.930.910'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02.200... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A direct descending pathway informing locomotor networks about tactile sensor movement. | Much like visually impaired humans use a white-cane, nocturnal insects and mammals use antennae or whiskers for near-range orientation. Stick insects, for example, rely heavily on antennal tactile cues to find footholds and detect obstacles. Antennal contacts can even induce aimed reaching movements. Because tactile se... | ['Animals', 'Arthropod Antennae', 'Female', 'Insecta', 'Interneurons', 'Locomotion', 'Movement', 'Neural Pathways', 'Sensory Receptor Cells', 'Touch', 'Touch Perception'] | 25,740,535 | [['B01.050'], ['A13.093'], ['B01.050.500.131.617'], ['A08.675.358', 'A11.671.358'], ['G07.568.500', 'G11.427.410.568'], ['G07.568', 'G11.427.410'], ['A08.612'], ['A08.675.650.915', 'A08.800.950', 'A11.671.650.915'], ['F02.830.816.850', 'G11.561.790.850'], ['F02.463.593.894']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alcohol, tobacco, diet, mate drinking, and esophageal cancer in Argentina. | To study the role of hot mate drinking, alcohol, tobacco, and diet in esophageal cancer, a case-control study including 131 cases and 262 hospital controls was carried out in La Plata, Argentina. In multivariate analyses, statistically significant increases in risk were detected for alcohol, tobacco, and some dietary f... | ['Aged', 'Alcohol Drinking', 'Argentina', 'Beverages', 'Carcinoma, Squamous Cell', 'Confidence Intervals', 'Cross-Sectional Studies', 'Dose-Response Relationship, Drug', 'Esophageal Neoplasms', 'Feeding Behavior', 'Female', 'Hot Temperature', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Odds Ratio', 'Risk Factors', '... | 7,827,585 | [['M01.060.116.100'], ['F01.145.317.269'], ['Z01.107.757.077'], ['G07.203.100', 'J02.200'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.690.773.875', 'G07.690.936.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Graphite tattoo: report of a case and differential diagnosis. | A case report underlining the necessity of the biopsy procedure for a pigmented lesion of unknown origin. A female patient was referred for evaluation of a pigmented lesion on the facial keratinized gingiva coronal to the free gingival margin above tooth No. 7. An excisional biopsy revealed a graphite tattoo. A discuss... | ['Adult', 'Diagnosis, Differential', 'Female', 'Gingival Diseases', 'Graphite', 'Humans', 'Melanosis', 'Pigmentation Disorders', 'Tattooing'] | 1,620,404 | [['M01.060.116'], ['E01.171'], ['C07.465.714.258'], ['D01.268.150.300', 'D01.578.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.621.430.530'], ['C17.800.621', 'C23.550.755'], ['E02.218.085.840', 'E04.085.840']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic variations in angiogenesis pathway genes associated with clinical outcome in localized gastric adenocarcinoma. | BACKGROUND: Angiogenesis has been attributed to be a well-recognized aspect of human cancer biology. As such, proteinase-activated receptor (PAR)-1, endostatin (ES) and interleukin-8 (IL-8) mediate the regulation of early-onset angiogenesis and in turn impact the process of tumor-growth and disease progression.PATIENTS... | ['Adenocarcinoma', 'Biomarkers, Tumor', 'Endostatins', 'Female', 'Genotype', 'Humans', 'Interleukin-8', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Neovascularization, Pathologic', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Polymorphism, Single Nucleotide', 'Rece... | 19,622,587 | [['C04.557.470.200.025'], ['D23.101.140'], ['D12.644.276.100.450.750', 'D12.776.467.100.450.750', 'D12.776.860.300.250.400.537.500', 'D23.529.100.450.750'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D12.776.467.374.200.120.800', 'D12.776.46... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Environmental stresses and strains in an extreme situation: the repair of electrometallurgy furnaces. | Whenever continuous casting furnace breaks down, the emergency intervention necessary to repair it has to be carried out under exceptional environmental conditions caused mainly by heat, as the furnace must be stopped for the shortest possible time. In this study, we aimed to evaluate the stresses and strains to which ... | ['Adult', 'Air Pollutants, Occupational', 'Arousal', 'Body Temperature Regulation', 'Carbon Dioxide', 'Carbon Monoxide', 'Carboxyhemoglobin', 'Environmental Monitoring', 'Heart Rate', 'Heat Exhaustion', 'Heating', 'Humans', 'Male', 'Metallurgy', 'Occupational Diseases', 'Occupational Exposure', 'Protective Clothing', '... | 8,144,236 | [['M01.060.116'], ['D27.888.284.101.268'], ['F02.830.104', 'G11.561.035'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['D12.776.124.400.141', 'D12.776.422.316.762.149'], ['N06.850.460.350.080', 'N06.850.780.375... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Quantifying Strength of Chaos in the Population Firing Rate of Neurons. | In this study, I considered quantifying the strength of chaos in the population firing rate of a pulse-coupled neural network. In particular, I considered the dynamics where the population firing rate is chaotic and the firing of each neuron is stochastic. I calculated a time histogram of firings to show the variation ... | ['Action Potentials', 'Animals', 'Bayes Theorem', 'Brain', 'Feedback, Physiological', 'Models, Neurological', 'Neural Inhibition', 'Neural Pathways', 'Neurons', 'Nonlinear Dynamics', 'Periodicity', 'Stochastic Processes', 'Synapses'] | 29,220,309 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['A08.186.211'], ['G07.410.732'], ['E05.599.395.642'], ['G07.265.755', 'G11.561.616'], ['A08.612'], ['A08.675', 'A11.671'], ['E05.599.850', 'H01.548.675'], ['G01.910.645', ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Use of response surface methodology in a fed-batch process for optimization of tricarboxylic acid cycle intermediates to achieve high levels of canthaxanthin from Dietzia natronolimnaea HS-1. | In this work, we applied statistical experimental design to a fed-batch process for optimization of tricarboxylic acid cycle (TCA) intermediates in order to achieve high-level production of canthaxanthin from Dietzia natronolimnaea HS-1 cultured in beet molasses. A fractional factorial design (screening test) was first... | ['Actinomycetales', 'Bioreactors', 'Biotechnology', 'Canthaxanthin', 'Citric Acid Cycle', 'Fermentation', 'Food Coloring Agents', 'Ketoglutaric Acids', 'Models, Biological', 'Oxaloacetic Acid', 'Succinic Acid'] | 20,226,378 | [['B03.510.024.049'], ['E07.115', 'J01.897.120.115'], ['H01.158.550', 'J01.897.120'], ['D02.455.326.271.665.202.868.249', 'D02.455.426.392.368.367.379.249.887.249', 'D02.455.849.131.868.249', 'D23.767.261.887.249'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['G02.111.158.249', 'G03.191.249'], ['D27.720.233.674', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Biosynthetic regulation of individual proteins in relA+ and relA strains of Escherichia coli during amino acid starvation. | An isogenic pair of Escherichia coli mutants (relA+ tufB valSts and relA1 tufB valSts) has been cultured at several temperatures to establish various degrees of limitation for valyl-tRNA synthetase. The biosynthetic rate of 16 identifiable proteins, most of which are components of the transcription and translation appa... | ['Amino Acids', 'Bacterial Proteins', 'Escherichia coli', 'Guanine Nucleotides', 'Kinetics', 'Leucine', 'Peptide Fragments', 'Protein Biosynthesis', 'Species Specificity', 'Transcription, Genetic', 'Uracil', 'Valine'] | 799,246 | [['D12.125'], ['D12.776.097'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D03.633.100.759.646.454', 'D13.695.667.454', 'D13.695.827.426'], ['G01.374.661', 'G02.111.490'], ['D12.125.070.637', 'D12.125.142.441'], ['D12.644.541'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['G16.824'], ['G02.111.873... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
QSAR studies on carbonic anhydrase inhibitors: a case of ureido and thioureido derivatives of aromatic/heterocyclic sulfonamides. | QSAR studies on modelling of biological activity (hCAI) for a series of ureido and thioureido derivatives of aromatic/heterocyclic sulfonamides have been made using a pool of topological indices. Regression analysis of the data showed that excellent results were obtained in multiparametric correlations upon introductio... | ['Animals', 'Carbonic Anhydrase Inhibitors', 'Cattle', 'Heterocyclic Compounds', 'Humans', 'Hydrocarbons, Aromatic', 'Quantitative Structure-Activity Relationship', 'Regression Analysis', 'Sulfonamides', 'Thiourea', 'Urea'] | 12,110,322 | [['B01.050'], ['D27.505.519.389.200'], ['B01.050.150.900.649.313.500.380.271'], ['D03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559'], ['G02.111.830.500', 'G07.690.773.997.500'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['D02.065.884', 'D02.886.590.700'], ['D02.065.950.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes. | Rapidly increasing availability of genomic data and ensuing identification of disease associated mutations allows for an unbiased insight into genetic drivers of disease development. However, determination of molecular mechanisms by which individual genomic changes affect biochemical processes remains a major challenge... | ['Cell Line', 'Humans', 'Mass Spectrometry', 'Multiprotein Complexes', 'Mutation', 'Neoplasm Proteins', 'Neoplasms', 'Phenotype', 'Phosphoproteins', 'Phosphorylation', 'Protein Conformation', 'Protein Interaction Maps', 'Protein Kinases', 'Protein-Serine-Threonine Kinases', 'Protein-Tyrosine Kinases', 'Proteome', 'Prot... | 32,678,104 | [['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D05.500'], ['G05.365.590'], ['D12.776.624'], ['C04'], ['G05.695'], ['D12.776.744'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['G02.111.570.820.709'], ['G03.493.750'], ['D08.811.913.696.620.682'], ['D08.811.913.696.620.682.700'], ['D... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sympathetic skin responses (SSRs) in monofocal brain lesions: topographical aspects of central sympathetic pathways. | Lesions of the central sympathetic pathways are likely to be of clinical relevance. In patients with acute stroke, in particular, they may be responsible for the partially deleterious cardiac arrhythmia. There is little knowledge of the central organization of sympathetic pathways above the brainstem level for both car... | ['Adult', 'Aged', 'Arousal', 'Brain Damage, Chronic', 'Brain Mapping', 'Brain Stem', 'Cerebral Infarction', 'Dominance, Cerebral', 'Female', 'Galvanic Skin Response', 'Humans', 'Male', 'Middle Aged', 'Neural Pathways', 'Reaction Time', 'Skin', 'Sweating', 'Sympathetic Nervous System'] | 7,639,067 | [['M01.060.116'], ['M01.060.116.100'], ['F02.830.104', 'G11.561.035'], ['C10.228.140.140'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.35... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inducible gene expression and protein translocation using nontoxic ligands identified by a mammalian three-hybrid screen. | The natural product rapamycin has been used to provide temporal and quantitative control of gene expression in animals through its ability to interact with two proteins simultaneously. A shortcoming of this approach is that rapamycin is an inhibitor of cell proliferation, the result of binding to FKBP12-rapamycin-assoc... | ['Animals', 'Biological Transport', 'Carrier Proteins', 'Cell Membrane', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Heat-Shock Proteins', 'Ligands', 'Molecular Structure', 'Polyenes', 'Proteins', 'Recombinant Fusion Proteins', 'Sirolimus', 'Tacrolimus Binding Proteins'] | 9,223,271 | [['B01.050'], ['G03.143'], ['D12.776.157'], ['A11.284.149'], ['D12.776.260'], ['G05.308'], ['D12.776.580.216'], ['D27.720.470.480'], ['G02.111.570', 'G02.466'], ['D02.455.326.271.665'], ['D12.776'], ['D12.776.828.300'], ['D02.540.505.760'], ['D08.811.399.325.500.400.700', 'D12.776.543.750.705.400.700', 'D12.776.827.275... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rhodoquinone and complex II of the electron transport chain in anaerobically functioning eukaryotes. | Many anaerobically functioning eukaryotes have an anaerobic energy metabolism in which fumarate is reduced to succinate. This reduction of fumarate is the opposite reaction to succinate oxidation catalyzed by succinate-ubiquinone oxidoreductase, complex II of the aerobic respiratory chain. Prokaryotes are known to cont... | ['Animals', 'Electron Transport', 'Electron Transport Complex II', 'Helminths', 'Kinetics', 'Multienzyme Complexes', 'Oxidation-Reduction', 'Oxidoreductases', 'Succinate Dehydrogenase', 'Ubiquinone'] | 8,537,365 | [['B01.050'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D05.500.562.750.249', 'D08.811.600.250.500.750', 'D08.811.600.250.875.249', 'D08.811.682.660.385', 'D08.811.682.830.249', 'D12.776.157.427.374.375.909', 'D12.776.331.199.750', 'D12.776.543.277.500.750', 'D12.776.543.277.875.249', 'D12.776.556.579.374.37... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective intubation of the afferent loop. | A selective intubation method for examination of the afferent loop is described and brief review of complications involving the afferent loop is outlined. The value of the intubation method in patient management is illustrated by three case reports. We find this a helpful method for studying selected patients with clin... | ['Adult', 'Afferent Loop Syndrome', 'Contrast Media', 'Diagnosis, Differential', 'Female', 'Humans', 'Intubation, Gastrointestinal', 'Male', 'Middle Aged', 'Radiography'] | 415,554 | [['M01.060.116'], ['C06.405.469.531.099', 'C23.550.767.050'], ['D27.505.259.500', 'D27.720.259'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.585.412', 'E05.497.412'], ['M01.060.116.630'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Efflux of osmolyte amino acids during isovolumic regulation in hippocampal slices. | The efflux of potassium (K(+)) and amino acids from hippocampal slices was measured after sudden exposure to 10% (270 mOsm), 25% (225 mOsm) or 50% (150 mOsm) hyposmotic solutions or after gradual decrease (-2.5 mOsm/min) in external osmolarity. In slices suddenly exposed to 50% hyposmotic solutions, swelling was follow... | ['Amino Acids', 'Animals', 'Aspartic Acid', 'Biological Transport', 'Chloride Channels', 'Colforsin', 'Cyclooxygenase Inhibitors', 'Hippocampus', 'Hypotonic Solutions', 'Male', 'Neurons', 'Niflumic Acid', 'Nitrobenzoates', 'Organ Culture Techniques', 'Osmolar Concentration', 'Potassium', 'Rats', 'Rats, Wistar', 'Rubidi... | 10,972,967 | [['D12.125'], ['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['G03.143'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['D02.455.849.291.300'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.030.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anticoagulation for cardiac surgery in patients receiving preoperative heparin: use of the high-dose thrombin time. | UNLABELLED: Patients receiving heparin infusions have an attenuated activated clotting time (ACT) response to heparin given for cardiopulmonary bypass (CPB). We compared patients receiving preoperative heparin (Group H) to those not receiving heparin (REF group) with respect to ACT, high-dose thrombin time (HiTT), and ... | ['Anticoagulants', 'Cardiopulmonary Bypass', 'Heparin', 'Humans', 'Thrombin Time', 'Whole Blood Coagulation Time'] | 10,735,781 | [['D27.505.954.502.119'], ['E04.292.413'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.625.115.870', 'E05.200.625.115.870', 'G09.188.840'], ['E01.370.225.625.115.950', 'E05.200.625.115.950', 'G09.188.960']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bullous pemphigoid induced by PUVA therapy. | An 80-year-old psoriatic patient developed a blistering eruption during oral PUVA therapy. The diagnosis of bullous pemphigoid (BP) was established by routine histopathology, which demonstrated subepidermal blistering, and direct immunofluorescence, which revealed linear deposits of IgG, IgM and C3 along the basement m... | ['Aged', 'Aged, 80 and over', 'Autoantibodies', 'Basement Membrane', 'Complement C3', 'Epidermis', 'Fluorescent Antibody Technique, Direct', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Immunoblotting', 'Immunoglobulin G', 'Immunoglobulin M', 'Male', 'Methoxsalen', 'PUVA Therapy', 'Pemphigoid, Bullous', 'Phot... | 8,944,349 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A10.272.220', 'A10.615.179'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['A10.272.497', 'A17.815.250'], ['E01.370.225.500.607.512.240.300', 'E01.370.225.750.551.512.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Double depression and episodic major depression: demographic, clinical, familial, personality, and socioenvironmental characteristics and short-term outcome. | The authors compared 31 outpatients with double depression to 50 outpatients with episodic major depression. Patients with double depression exhibited significantly greater impairment, more severe depressive symptoms, greater comorbidity, more personality disturbance, lower levels of social support, more chronic strain... | ['Adult', 'Ambulatory Care', 'Bipolar Disorder', 'Cyclothymic Disorder', 'Depressive Disorder', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mood Disorders', 'Outcome and Process Assessment, Health Care', 'Personality Disorders', 'Psychiatric Status Rating Scales', 'Social Support'] | 3,421,343 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['F03.084.500'], ['F03.600.500'], ['F03.600.300'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.600'], ['N04.761.559', 'N05.715.360.575'], ['F03.675'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effectiveness of a topical antifungal regimen for the treatment of oral candidiasis in older, chronically ill, institutionalized, adults. | Because of predisposing systemic disease, the frequent administration of medication, and the use of a complete denture, oral candidiasis is a common problem among older, chronically ill, institutionalized adults. This randomized clinical trial was designed to evaluate the effectiveness of an antifungal denture soaking ... | ['Aged', 'Candidiasis, Oral', 'Chi-Square Distribution', 'Dental Care for Aged', 'Denture Cleansers', 'Denture, Complete, Upper', 'Female', 'Humans', 'Life Tables', 'Male', 'Nursing Homes', 'Nystatin'] | 7,773,850 | [['M01.060.116.100'], ['C01.150.703.160.180', 'C07.465.130'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E06.170.100', 'N02.421.240.190.210'], ['D25.376.262', 'J01.637.051.376.262'], ['E06.780.346.760.775.504', 'E07.695.190.200.205.215'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
A new approach towards the synthesis of pseudaminic acid analogues. | The pseudaminic acids are a family of 5,7-diamino-3,5,7,9-tetradeoxynonulosonic acids that are essential components of bacterial polysaccharides and glycoproteins. This paper describes our approach towards the synthesis of analogues of pseudaminic acid, and involves the efficient introduction of the requisite nitrogen ... | ['Azides', 'Chemistry, Organic', 'N-Acetylneuraminic Acid', 'Sugar Acids'] | 24,687,140 | [['D01.625.100', 'D02.159'], ['H01.181.404'], ['D02.241.081.844.562.668.050', 'D02.241.511.902.562.668.050', 'D09.067.687.668.030', 'D09.811.589.668.030'], ['D02.241.081.844', 'D02.241.511.902', 'D09.811']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioral and endocrine consequences of simultaneous exposure to two different stressors in rats: interaction or independence? | Although behavioral and endocrine consequences of acute exposure to stressors have been extensively studied, little is known about how simultaneous exposure to two different stressors interacts to induce short- and long-term effects. In the present experiment we studied this interaction in adult male rats exposed to ca... | ['Adrenocorticotropic Hormone', 'Animals', 'Behavior, Animal', 'Cats', 'Corticosterone', 'Endocrine System', 'Male', 'Maze Learning', 'Odorants', 'Rats', 'Rats, Sprague-Dawley', 'Restraint, Physical', 'Stress, Psychological', 'Time Factors'] | 21,731,743 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['F01.145.113'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D04.210.500.745.745.654.237', 'D06.472... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Component Release and Mechanical Properties of Endodontic Sealers following Incorporation of Antimicrobial Agents. | Root canal sealers with antimicrobial activity are highly beneficial; therefore, their antimicrobial properties could be improved by incorporation of antimicrobial agents. In the present study, the release of the quaternary ammonium compounds from endodontic sealers admixed with either benzalkonium chloride (BC) or cet... | ['Anti-Infective Agents', 'Benzalkonium Compounds', 'Cetylpyridinium', 'Enterococcus faecalis', 'Epoxy Resins', 'Humans', 'Materials Testing', 'Quaternary Ammonium Compounds', 'Root Canal Filling Materials', 'Zinc Oxide-Eugenol Cement'] | 28,620,615 | [['D27.505.954.122'], ['D02.092.877.096.040', 'D02.675.276.080'], ['D03.383.725.762.232'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['D05.750.716.822.461', 'D25.720.716.822.461', 'J01.637.051.720.716.822.461'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['D01.625.062.500', 'D02.092.877... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Moraxella catarrhalis strains with reduced expression of the UspA outer membrane proteins belong to a distinct subpopulation. | The outer membrane proteins UspA1 and UspA2 are candidate antigens for a Moraxella catarrhalis vaccine. We previously reported that 103 of 108 isolates (95%) from young children expressed UspA1 detected by reactivity with the monoclonal antibody mAb24B5. The aim of the present study was to investigate mechanisms contro... | ['Amino Acid Sequence', 'Antibodies, Monoclonal', 'Bacterial Outer Membrane Proteins', 'Base Sequence', 'Blotting, Western', 'Cell-Free System', 'DNA, Bacterial', 'Enzyme-Linked Immunosorbent Assay', 'Flow Cytometry', 'Molecular Sequence Data', 'Moraxella catarrhalis', 'Reverse Transcriptase Polymerase Chain Reaction',... | 15,734,074 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.097.120', 'D12.776.543.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Herbicidal effects of soil-incorporated wheat. | The hydroxamic acid 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and the benzoxazolinones benzoxazolin-2-one (BOA) and 6-methoxybenzoxazolin-2-one (MBOA) have been identified as important allelochemicals in wheat. This study examines the possibility of exploiting the allelopathic properties of wheat as a weed ... | ['Benzoxazines', 'Benzoxazoles', 'Dose-Response Relationship, Drug', 'Germination', 'Herbicides', 'Oxazines', 'Pheromones', 'Poaceae', 'Soil', 'Triticum'] | 16,478,217 | [['D03.383.533.249', 'D03.633.100.209'], ['D03.633.100.221'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.345.625.249', 'G15.357'], ['D27.720.031.700.366', 'D27.888.723.366'], ['D03.383.533'], ['D23.641'], ['B01.650.940.800.575.912.250.822'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.650.940... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Correlation between the mode of presentation of renal tumors and patient survival]. | OBJECTIVES: To establish a symptom score and to test its prognostic value in comparison with the usual histological prognostic criteria.MATERIAL AND METHODS: 388 renal tumours were classified into three symptomatic grades according to the circumstances of discovery: S1: incidental discovery, S2; patient presenting with... | ['Carcinoma, Renal Cell', 'Female', 'Follow-Up Studies', 'Humans', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Nephrectomy', 'Retrospective Studies', 'Time Factors'] | 12,703,350 | [['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of self-reinforcement and peer-reinforcement on the practice of breast self-examination. | Four months after learning breast self-examination (BSE), 169 sorority women assigned to one of three conditions (No Reinforcement, Self-Reinforcement or Peer-Reinforcement) were compared on BSE frequency subsequent to the training. Participants in both of the reinforcement conditions had agreed to a specified reward ... | ['Adult', 'Analysis of Variance', 'Anxiety', 'Breast Neoplasms', 'Breast Self-Examination', 'Female', 'Follow-Up Studies', 'Health Education', 'Health Knowledge, Attitudes, Practice', 'Health Promotion', 'Humans', 'Peer Group', 'Reinforcement, Social'] | 10,148,738 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.470.132'], ['C04.588.180', 'C17.800.090.500'], ['E01.370.600.750.100', 'F01.145.488.700.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I02.233.332', 'N02.421.726.407'], ['F01.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Raising the Joint Line in TKA is Associated With Mid-flexion Laxity: A Study in Cadaver Knees. | BACKGROUND: In a typical osteoarthritic knee with varus deformity, distal femoral resection based off the worn medial femoral condyle may result in an elevated joint line. In a setting of fixed flexion contracture, the surgeon may choose to resect additional distal femur to obtain extension, thus purposefully raising t... | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Knee', 'Biomechanical Phenomena', 'Cadaver', 'Female', 'Femur', 'Humans', 'Joint Instability', 'Knee Joint', 'Knee Prosthesis', 'Male', 'Medial Collateral Ligament, Knee', 'Middle Aged', 'Models, Anatomic', 'Random Allocation', 'Range of Motion, Articular', 'Ris... | 29,443,845 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['A02.835.583.475'], ['E07.695.400.410'], ['A02.513.514.162.60... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Data (pre-)processing of nominal and accurate mass LC-MS or GC-MS data using MetAlign. | This paper gives a step-by-step account of how to install, set up, and run MetAlign software, which can be downloaded freely ( http://www.metalign.wur.nl/UK/Download+and+publications ). The software is used for accurate mass and nominal mass data coming from differen... | ['Algorithms', 'Chromatography, Gas', 'Chromatography, Liquid', 'Mass Spectrometry', 'Molecular Weight', 'Software'] | 22,351,181 | [['G17.035', 'L01.224.050'], ['E05.196.181.349'], ['E05.196.181.400'], ['E05.196.566'], ['G02.494'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Arabidopsis KLU homologue GmCYP78A72 regulates seed size in soybean. | Soybean (Glycine max) is one of the most important crops in the world, and its yield is largely determined by grain weight and grain size. However, the genes that regulate soybean seed size have not been identified. CYP78A, which is highly conserved within terrestrial plants, regulates organ development. In Arabidopsis... | ['Arabidopsis', 'Arabidopsis Proteins', 'Cytochrome P-450 Enzyme System', 'Flowers', 'Gene Expression', 'Gene Expression Regulation, Plant', 'Gene Silencing', 'Phenotype', 'Phylogeny', 'Plant Leaves', 'Plant Proteins', 'Plants, Genetically Modified', 'Seeds', 'Sequence Alignment', 'Soybeans'] | 26,482,479 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A18.024.249.500'], ['G05.297'], ['G05.308.375'], ['G05.308.203.374'], ['G05.695'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['A18.024.812'], ['D12.776.765'], ['B01.650.520', 'B05.620.600... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Prevalence of extended-spectrum â-lactamase-producing Enterobacteriaceae and Methicillin-Resistant Staphylococcus aureus in pig farms in Switzerland. | The presence of Methicillin-Resistant Staphylococcus aureus (MRSA) in pig farms has been widely reported, and the emergence of extended-spectrum â-lactamase-producing Enterobacteriaceae (ESBL-E) has been documented in several countries. However, data for Switzerland are very scarce. This study aimed to compare changes ... | ['Air Microbiology', 'Animals', 'Enterobacteriaceae', 'Farms', 'Feces', 'Humans', 'Methicillin-Resistant Staphylococcus aureus', 'Nose', 'Prevalence', 'Swine', 'Switzerland', 'beta-Lactamases'] | 28,636,975 | [['H01.158.273.540.274.110', 'N06.850.425.110'], ['B01.050'], ['B03.440.450.425', 'B03.660.250.150'], ['J01.040.372', 'J03.540.150'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.300.390.400.800.750.100.500', 'B03.353.500.750.750.100.500', 'B03.510.100.750.750.100.500', 'B03.510.400.790.750.100.5... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
[Daily calorie and macronutrient consumption in girls of different somatotypes with different shares of body fat, muscle and bone components]. | 211 practically healthy girls, the students of Krasnoyarsk Medical University in the ages of 16 to 20 years, have been examined. We determined their somatotypes (euriplastic, athletic, subathletic and stenoplastic) and body composition (fat, muscle, bone component). Actual nutrition in these subjects was studied by the... | ['Adipose Tissue', 'Adolescent', 'Adult', 'Body Height', 'Body Mass Index', 'Body Weight', 'Bone and Bones', 'Energy Intake', 'Energy Metabolism', 'Female', 'Humans', 'Muscle, Skeletal', 'Nutritional Requirements', 'Somatotypes', 'Young Adult'] | 27,455,598 | [['A10.165.114'], ['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Scientific knowledge and the methodologic problem of pain in medicine]. | The paper discusses the epistemological question of pain and the way this concept forms part of scientific knowledge. The first part gives a rapid overview of the main aspects of modern scientific knowledge. In earlier times Bacon, Galileo and Descartes felt that the new form of knowledge could head to a knowledge of t... | ['History, 15th Century', 'History, 16th Century', 'History, 20th Century', 'History, Medieval', 'Humans', 'Knowledge', 'Pain', 'Philosophy', 'Religion', 'Science'] | 10,522,141 | [['K01.400.475.500'], ['K01.400.475.750'], ['K01.400.504.968'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.468'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['K01.752'], ['K01.844'], ['H01.770']] | ['Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. | Generation of reactive oxygen species (ROS), leading to oxidative damage and neuronal cell death, plays an important role in the pathogenesis of neurodegenerative disorders, including Alzheimer disease. The present study aimed to examine the mechanism by which the anti-aging protein Klotho exerts neuroprotective effect... | ['Animals', 'Female', 'Glucuronidase', 'Mice', 'Mice, Inbred C57BL', 'Neurons', 'Oxidation-Reduction', 'Oxidative Stress', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Reactive Oxygen Species'] | 25,037,225 | [['B01.050'], ['D08.811.277.450.426'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A08.675', 'A11.671'], ['G02.700', 'G03.295.531'], ['G03.673', 'G07.775.750'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunolocation of TNF-alpha/cachectin in human melanoma cells: studies on co-cultivated malignant melanoma. | We have investigated the ability of metastatic cells to produce the macrophage cytokine, TNF-alpha/cachectin, as these cells have macrophage-like properties such as infiltration and migration. We looked for TNF-alpha/cachectin in three tumor cell lines derived from human malignant melanomas and six co-cultivated malign... | ['Adolescent', 'Adult', 'Antibodies, Monoclonal', 'Blotting, Northern', 'Cell Communication', 'Cell Line', 'DNA Probes', 'Female', 'Hemangioma', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Melanoma', 'RNA, Messenger', 'Tumor Cells, Cultured', 'Tumor Necrosis Factor-alpha'] | 1,991,983 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G04.085'], ['A11.251.210'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['C04.557.645.375'], ['B01.050... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fasting and diabetes mellitus elicit opposite effects on agonist-stimulated prostacyclin synthesis by the rat aorta. | The effects of prolonged fasting and experimental nonketonuric diabetes on rat aortic prostacyclin (PGl2) synthesis were compared. Whereas fasting (for 48 hours or longer) resulted in a marked increase in trauma-, adrenaline-, and U46619-stimulated aortic PGI2 synthesis, prolonged experimental (streptozotocin-induced) ... | ['Animals', 'Aorta, Thoracic', 'Blood Glucose', 'Blood Vessels', 'Diabetes Mellitus, Experimental', 'Epinephrine', 'Epoprostenol', 'Fasting', 'Fatty Acids, Nonesterified', 'Male', 'Prostaglandin Endoperoxides, Synthetic', 'Rats', 'Rats, Inbred Strains', 'Wounds and Injuries'] | 3,298,934 | [['B01.050'], ['A07.015.114.056.372'], ['D09.947.875.359.448.500'], ['A07.015'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.72... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronochemotherapy: L 1210 leukemia and beyond. | In cancer and other therapeutic research, an interpretation of median survival times can and should take cure into account. With this qualification, an analysis of recently published data provides further statistically significant evidence in favor of cancer chronotherapy as compared to homeostatic therapy. | ['Animals', 'Circadian Rhythm', 'Cyclophosphamide', 'Cytarabine', 'Drug Administration Schedule', 'Leukemia L1210', 'Mice'] | 520,097 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Towards a definition of glomerulomegaly: clinical-pathological and methodological considerations. | BACKGROUND: Glomerulomegaly, the abnormal enlargement of glomeruli, has been related to an increased risk of glomerulosclerosis, but the degree of enlargement that constitutes glomerulomegaly has not been defined.METHODS: The principal stereological methods for estimating glomerular volume are [1] the disector/Cavalier... | ['Adult', 'African Americans', 'Aged', 'Autopsy', 'Body Mass Index', 'European Continental Ancestry Group', 'Female', 'Glomerulosclerosis, Focal Segmental', 'Humans', 'Hypertension', 'Kidney Glomerulus', 'Male', 'Middle Aged', 'Obesity', 'Young Adult'] | 21,115,671 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.686.508.400'], ['C12.777.419.570.363.660', 'C13.351.968.419.570.363.640'], ['B01.050.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Orange-Emissive Carbon Quantum Dots: Toward Application in Wound pH Monitoring Based on Colorimetric and Fluorescent Changing. | Monitoring of wound pH is critical for interpreting wound status, because early identification of wound infection or nonhealing wounds is conducive to administion of therapies at the right time. Here, novel orange-emissive carbon quantum dots (O-CDs) are synthesized via microwave-assisted heating of 1,2,4-triaminobenze... | ['Animals', 'Carbon', 'Cell Death', 'Cell Line', 'Colorimetry', 'Hydrogen-Ion Concentration', 'Light', 'Mice', 'Quantum Dots', 'Rats', 'Solutions', 'Spectrometry, Fluorescence', 'Wound Healing'] | 31,518,068 | [['B01.050'], ['D01.268.150'], ['G04.146'], ['A11.251.210'], ['E05.196.922.250'], ['G02.300'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.992.635.505.500'], ['E07.705', 'J01.637.512.600.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['D26.776'], ['E05.19... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Experience on the treatment of acute anorectal abscess with primary fistulotomy]. | From August 1985 to July 1989, 72 cases with initial attacks of acute cryptoglandular anorectal abscesses were hospitalized and treated in Kuang Tien General Hospital. Among them were 52 cases of the perianal type, 8 of the intersphincteric type, 11 of the ischiorectal type and one case involving the supralevator space... | ['Abscess', 'Acute Disease', 'Adolescent', 'Adult', 'Anus Diseases', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Rectal Diseases', 'Rectal Fistula', 'Recurrence'] | 2,362,300 | [['C01.830.025', 'C23.550.470.756.100'], ['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['C06.405.469.860.101'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.405.469.860'], ['C06.267.550.600... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oral health status, salivary factors and microbial analysis in patients with active gastro-oesophageal reflux disease. | AIM: To present a complex oral health status including salivary factors, microbial analysis and periodontal and hygiene indices in patients with active gastro-oesophageal reflux disease (GORD). Return of stomach contents is quite common in cases of gastro-oesophageal reflux. Pathological acid movement from the stomach ... | ['Adult', 'Buffers', 'Colony Count, Microbial', 'DMF Index', 'Dental Caries', 'Dental Plaque', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Lactobacillus', 'Male', 'Manometry', 'Middle Aged', 'Oral Health', 'Periodontal Index', 'Risk Factors', 'Saliva', 'Secretory Rate', 'Streptococcus ... | 21,851,356 | [['M01.060.116'], ['D27.720.470.280'], ['E01.370.225.875.220', 'E05.200.875.220'], ['E05.318.308.980.438.300.350', 'E06.208.266', 'N05.715.360.300.800.438.300.340', 'N06.850.520.308.980.438.300.350', 'N06.890.160.100'], ['C07.793.720.210'], ['C07.793.208.377'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of arm-specific and subtelomeric region-specific painting probes for Chinese hamster chromosomes and their utility in chromosome identification of Chinese hamster cell lines. | Arm-specific and subtelomeric region-specific painting probes for Chinese hamster chromosomes have been generated by microdissection and use of the degenerate oligonucleotide-primed polymerase chain reaction (DOP-PCR). Fluorescence in situ hybridization (FISH) analyses using these probes demonstrated their specificity.... | ['Animals', 'CHO Cells', 'Cells, Cultured', 'Chromosome Mapping', 'Chromosome Painting', 'Chromosomes', 'Cricetinae', 'DNA Probes', 'Embryo, Mammalian', 'In Situ Hybridization, Fluorescence', 'Telomere'] | 10,072,579 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['A11.251'], ['E05.393.183'], ['E01.370.225.500.620.670.325.350.125', 'E01.370.225.750.600.670.325.350.125', 'E05.200.500.620.670.325.350.125', 'E05.200.750.600.670.325.350.125', 'E05.393.285.350.125', 'E05.393.661.475.350.125'], ['A11.284.187', 'A11.284.430.106.279.345... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The practical benefits of ambulatory continuous ECG recording]. | The diagnostic yield from ambulatory continuous ECG recording (Holter ECG) has been evaluated retrospectively in 200 consecutive patients referred from an urban population of 250,000 for arrhythmia diagnosis or evaluation. About half of the patients were in hospital, the other half were ambulatory. In 20/200 (10%) the ... | ['Arrhythmias, Cardiac', 'Electrocardiography, Ambulatory', 'Humans', 'Retrospective Studies'] | 8,480,288 | [['C14.280.067', 'C23.550.073'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.45... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Endothelial cell adhesion molecule expression in gene-targeted mice. | Gene-targeted mice are now routinely employed as tools for defining the contribution of different leukocyte and endothelial cell adhesion molecules to the leukocyte recruitment and tissue injury associated with acute and chronic inflammation. The objective of this study was to determine whether gene-targeted mice that ... | ['Animals', 'Blood Vessels', 'CD11 Antigens', 'CD18 Antigens', 'E-Selectin', 'Gene Targeting', 'Intercellular Adhesion Molecule-1', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred Strains', 'P-Selectin', 'Reference Values', 'Tumor Necrosis Factor-alpha'] | 9,362,259 | [['B01.050'], ['A07.015'], ['D12.776.395.550.200.074', 'D12.776.543.550.200.093', 'D23.050.301.350.074'], ['D12.776.395.550.200.275.750', 'D12.776.543.550.200.275.750', 'D12.776.543.750.705.408.200.249', 'D12.776.543.750.705.408.600.100.750', 'D12.776.543.750.705.833.249.750', 'D23.050.301.264.894.118', 'D23.050.301.35... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypomethylation of ETS transcription factor binding sites and upregulation of PARP1 expression in endometrial cancer. | Although PARP1 promoter methylation is involved in the regulation of PARP1 expression in human keratinocyte lines and lymphoblastoid cell lines, its roles in human endometrial cancer are unknown. DNA from forty normal endometrium (NE) and fifty endometrial adenocarcinoma (EAC) tissues were analyzed by bisulfite sequenc... | ['Adenocarcinoma', 'Binding Sites', 'DNA Methylation', 'Endometrial Neoplasms', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Middle Aged', 'Poly (ADP-Ribose) Polymerase-1', 'Poly(ADP-ribose) Polymerases', 'Promoter Regions, Genetic', 'Protein Binding', 'Proto-Oncogene Protein c-ets-1', 'RNA, Messenger... | 23,762,867 | [['C04.557.470.200.025'], ['G02.111.570.120'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D08.811.913.400.725.115.690.420... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prediction of Biopharmaceutical Drug Disposition Classification System (BDDCS) by Structural Parameters. | Modeling of physicochemical and pharmacokinetic properties is important for the prediction and mechanism characterization in drug discovery and development. Biopharmaceutics Drug Disposition Classification System (BDDCS) is a four-class system based on solubility and metabolism. This system is employed to delineate the... | ['Biopharmaceutics', 'Models, Theoretical', 'Molecular Structure', 'Pharmaceutical Preparations', 'Solubility'] | 31,287,788 | [['H01.158.703.003', 'H02.628.049'], ['E05.599'], ['G02.111.570', 'G02.466'], ['D26'], ['G02.805']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
An explanation of the upward drift in oxygen uptake during prolonged sub-maximal downhill running. | The upward drift in oxygen uptake (UDO) that occurs during some prolonged sub-maximal exercises involving eccentric muscle action has received only scant attention in the literature. Those papers reporting UDO have generally used bicycling on an ergometer modified for eccentric exercise as the experimental activity. Th... | ['Adult', 'Electromyography', 'Humans', 'Male', 'Muscles', 'Oxygen Consumption', 'Pain', 'Running'] | 3,600,246 | [['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633', 'A10.690'], ['G03.680'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Variability in laboratory reporting practices for regions of homozygosity indicating parental relatedness as identified by SNP microarray testing. | PURPOSE: Single-nucleotide polymorphism (SNP) microarrays are capable of detecting regions of homozygosity (ROH) that can suggest parental consanguinity or incest. This study was designed to describe the variable reporting practices of clinical laboratories in the United States regarding ROH found on SNP microarray tes... | ['Consanguinity', 'Disclosure', 'Genetic Testing', 'Homozygote', 'Humans', 'Incest', 'Laboratory Personnel', 'Observer Variation', 'Oligonucleotide Array Sequence Analysis', 'Polymorphism, Single Nucleotide', 'Surveys and Questionnaires', 'United States'] | 22,791,212 | [['G05.090.403.180', 'G05.180'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.442'], ['M01.526.502'], ['E01.354.753', 'N02.421.45... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Comparison of Rates of Hospitalization and Emergency Department Visits Using Self-Report and South Carolina Administrative Billing Data Among a Population-Based Cohort With Spinal Cord Injury. | OBJECTIVE: To compare self-report and South Carolina administrative billing data documentation of emergency department (ED) visits and hospitalizations in the past 12 months among a population-based cohort of persons with spinal cord injury (SCI).DESIGN: Cross-sectional study.SETTING: SCI surveillance system in South C... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Data Collection', 'Emergency Service, Hospital', 'Female', 'Health Status', 'Hospitalization', 'Humans', 'Insurance Claim Review', 'Male', 'Mental Health', 'Middle Aged', 'Self Report', 'Socioeconomic Factors', 'South Carolina', 'Spinal Cord Injuries', 'Trauma Severity Indi... | 27,084,264 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
YMF: A program for discovery of novel transcription factor binding sites by statistical overrepresentation. | A fundamental challenge facing biologists is to identify DNA binding sites for unknown regulatory factors, given a collection of genes believed to be coregulated. The program YMF identifies good candidates for such binding sites by searching for statistically overrepresented motifs. More specifically, YMF enumerates al... | ['Algorithms', 'Binding Sites', 'Data Interpretation, Statistical', 'Internet', 'Mycobacterium tuberculosis', 'Promoter Regions, Genetic', 'Regulatory Sequences, Nucleic Acid', 'Saccharomyces cerevisiae', 'Sequence Analysis, DNA', 'Software', 'Transcription Factors', 'User-Computer Interface'] | 12,824,371 | [['G17.035', 'L01.224.050'], ['G02.111.570.120'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['L01.224.230.110.500'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Endoscopic transanal resection using the urological resectoscope in the management of patients with rectal villous adenomas. | BACKGROUND AND AIMS: This study reviewed the outcome of endoscopic transanal resection (ETAR) for the treatment of patients with villous rectal adenomas (VRA).PATIENTS AND METHODS: This study included 28 consecutive patients who underwent ETAR for VRA between October 1992 and December 2000. All tumors were believed to ... | ['Adenoma, Villous', 'Adult', 'Aged', 'Aged, 80 and over', 'Anal Canal', 'Endoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Postoperative Complications', 'Rectal Neoplasms', 'Reoperation', 'Retrospective Studies', 'Treatment Outcome'] | 15,103,489 | [['C04.557.470.035.185'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['C23.550.767'], ['C04.588.274.476.411.30... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Heterogeneity in Pseudomonas aeruginosa biofilms includes expression of ribosome hibernation factors in the antibiotic-tolerant subpopulation and hypoxia-induced stress response in the metabolically active population. | Bacteria growing in biofilms are physiologically heterogeneous, due in part to their adaptation to local environmental conditions. Here, we characterized the local transcriptome responses of Pseudomonas aeruginosa growing in biofilms by using a microarray analysis of isolated biofilm subpopulations. The results demonst... | ['Anti-Bacterial Agents', 'Bacterial Proteins', 'Biofilms', 'Ciprofloxacin', 'Drug Resistance, Bacterial', 'Gene Expression Regulation, Bacterial', 'Oxygen', 'Pseudomonas aeruginosa', 'Stress, Physiological', 'Tobramycin'] | 22,343,293 | [['D27.505.954.122.085'], ['D12.776.097'], ['A20.593', 'G06.120'], ['D03.633.100.810.835.322.186'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['G05.308.300'], ['D01.268.185.550', 'D01.362.670'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['G07.775'], ['D09.408.051.476.600.800']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dicarabrol, a new dimeric sesquiterpene from Carpesium abrotanoides L. | A new dimeric sesquiterpene, dicarabrol (1), together with three known sesquiterpenes, carabrol (2), 11(13)-dehydroivaxillin (3), and 2-desoxy-4-epi-pulchellin (4), were isolated from the whole plant of Carpesium abrotanoides L. Their structures were elucidated on the basis of spectroscopic analysis, and single crystal... | ['Antineoplastic Agents, Phytogenic', 'Asteraceae', 'Cell Line, Tumor', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Drug Screening Assays, Antitumor', 'Humans', 'Models, Molecular', 'Molecular Conformation', 'Sesquiterpenes', 'Structure-Activity Relationship'] | 26,316,467 | [['D27.505.954.248.179'], ['B01.650.940.800.575.912.250.100'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Supraciliary shunt in refractory glaucoma. | AIMS: This study aimed to evaluate the efficacy of Gold Micro Shunt (GMS) for suprachoroidal drainage in patients with refractory glaucoma.METHODS: This is a prospective uncontrolled case series study. Fifty-five eyes of 55 patients were included. Study eyes underwent GMS implantation in the supraciliary space. Follow-... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Glaucoma', 'Glaucoma Drainage Implants', 'Gonioscopy', 'Humans', 'Hyphema', 'Intraocular Pressure', 'Male', 'Microscopy, Acoustic', 'Middle Aged', 'Prosthesis Design', 'Prosthesis Implantation', 'Reoperation', 'Treatment Outcome', 'Visual Acuity', 'Visual ... | 21,873,316 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.525.381'], ['E07.695.250'], ['E01.370.380.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.290.484', 'C23.550.414.756.550'], ['G14.440'], ['E01.370.350.515.370', 'E01.370.350.850.565', 'E05.595.370'], ['M01.060.116.630']... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The mercury levels in crustaceans and cephalopods from Peninsular Malaysia. | This study is to determine total mercury in edible tissues of eight species of cephalopods and 12 species of crustaceans purchased from 11 identified major fish landing ports and wet markets throughout Peninsular Malaysia. The concentration of mercury was measured by cold vapor atomic absorption spectrometry (AAS) tech... | ['Animals', 'Body Size', 'Cephalopoda', 'Crustacea', 'Malaysia', 'Mercury', 'Water Pollutants, Chemical'] | 25,916,470 | [['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.500.644.116'], ['B01.050.500.131.365'], ['Z01.252.145.487'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Primary non-Hodgkin's lymphomas of the CNS. | This paper reports on 10 patients (4 male, 6 female) with primary non-Hodgkin's lymphomas of the brain (CNS-NHL--mean age 46.8 years, mean postdiagnostic survival 10 months). Pathological CSF (cerebrospinal fluid) was found in all 8 patients examined (positive cytology in 7/8 cases). Solitary tumors, diffuse periventri... | ['Adult', 'Aged', 'Brain Neoplasms', 'Cerebral Angiography', 'Child, Preschool', 'Female', 'Humans', 'Lymphoma', 'Male', 'Middle Aged', 'Prognosis', 'Tomography, X-Ray Computed'] | 3,751,501 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Haematospermia as a presenting symptom: outcomes of investigation in 300 men. | BACKGROUND AND AIMS: The optimum investigation of haematospermia is unknown. The association of this condition in relation to pathology and in particular prostate cancer is controversial and there is a paucity of evidence based literature regarding the above. The aim of this study was to investigate haematospermia as a... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Follow-Up Studies', 'Hemospermia', 'Humans', 'Incidence', 'Male', 'Mass Screening', 'Middle Aged', 'Physical Examination', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Retrospective Studies', 'United Kingdom', 'Young Adult'] | 22,682,581 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C12.294.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Characterization of fungal antagonistic bacilli isolated from aerial roots of banyan (Ficus benghalensis) using intact-cell MALDI-TOF mass spectrometry (ICMS). | AIMS: To characterize fungal antagonistic bacilli isolated from aerial roots of banyan tree and identify the metabolites responsible for their antifungal activity.METHODS AND RESULTS: Seven gram positive, endospore-forming, rod-shaped endophytic bacterial strains exhibiting a broad-spectrum antifungal activity were iso... | ['Antibiosis', 'Bacillus', 'Bacillus subtilis', 'Biological Control Agents', 'Endophytes', 'Ficus', 'Fungi', 'Lipopeptides', 'Mass Spectrometry', 'Peptides, Cyclic', 'Plant Roots', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 23,387,377 | [['G06.550.050', 'G16.062'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D20.215.113... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rational design and bioimaging applications of highly selective fluorescence probes for hydrogen polysulfides. | Reactive sulfur species have received considerable attention due to their various biological functions. Among these molecules, hydrogen polysulfides (H2S(n), n > 1) are recently suggested to be the actual signaling molecules derived from hydrogen sulfide (H2S). Hydrogen polysulfides may also have their own biosynthetic... | ['Fluorescent Dyes', 'Hydrogen Sulfide', 'Molecular Structure', 'Sulfides'] | 24,809,803 | [['D27.720.233.348', 'D27.720.470.410.505.500'], ['D01.029.260.340', 'D01.362.350', 'D01.875.350'], ['G02.111.570', 'G02.466'], ['D01.248.497.158.874', 'D01.875.350.850', 'D02.886.520']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Some major transport mechanisms of insect absorptive epithelia. | 1. After hormonal stimulation, fluid reabsorption (JV) in locust hindgut from the KCl-rich, low-Na primary urine is driven primarily by an unusual mucosal electrogenic Cl- pump (JCl). 2. Cyclic-AMP increases JCl and also mucosal K+ and basolateral Cl- conductances, so that KCl absorption exceeds that of Na+ in rectum b... | ['Absorption', 'Amino Acids', 'Animals', 'Chlorides', 'Digestive System', 'Epithelium', 'Grasshoppers', 'Potassium', 'Sodium'] | 2,902,972 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['D12.125'], ['B01.050'], ['D01.210.450.150', 'D01.248.497.158.215'], ['A03'], ['A10.272'], ['B01.050.500.131.617.678.369'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The additional ACh binding site at the á4(+)/á4(-) interface of the (á4â2)2á4 nicotinic ACh receptor contributes to desensitization. | BACKGROUND AND PURPOSE: Nicotinic ACh (á4â2)2á4 receptors are highly prone to desensitization by prolonged exposure to low concentrations of agonist. Here, we report on the sensitivity of the three agonist sites of the (á4â2)2á4 to desensitization induced by prolonged exposure to ACh. We present electrophysiological da... | ['Acetylcholine', 'Animals', 'Binding Sites', 'Ligands', 'Nicotinic Agonists', 'Oocytes', 'Patch-Clamp Techniques', 'Point Mutation', 'Receptors, Nicotinic', 'Time Factors', 'Xenopus laevis'] | 23,742,319 | [['D02.092.211.111'], ['B01.050'], ['G02.111.570.120'], ['D27.720.470.480'], ['D27.505.519.625.120.140.700', 'D27.505.696.577.120.140.700'], ['A05.360.490.690.680', 'A11.497.497.600'], ['E05.200.500.905', 'E05.242.800'], ['G05.365.590.675'], ['D12.776.157.530.400.400.100.500', 'D12.776.543.550.450.500.100.500', 'D12.77... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Population genetics of hereditary hemochromatosis in Saguenay Lac-Saint-Jean (Quebec, Canada). | Hereditary hemochromatosis (HH) is an autosomal recessive disorder that has a high prevalence in Caucasian populations. Based on HLA typing in 18 families, the gene frequency was estimated 0.12. The homozygote frequency was 0.014 and the heterozygote frequency was 0.21 in Saguenay Lac-Saint-Jean (SLSJ), a geographicall... | ['Consanguinity', 'Female', 'Gene Frequency', 'Genes, Recessive', 'Genotype', 'Hemochromatosis', 'Humans', 'Male', 'Pedigree', 'Prevalence', 'Quebec'] | 1,296,515 | [['G05.090.403.180', 'G05.180'], ['G05.330'], ['G05.360.340.024.340.415', 'G05.420.325'], ['G05.380'], ['C16.320.565.618.337', 'C18.452.565.500.480', 'C18.452.648.618.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.673'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750'... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Comparison of C18 silica bonded phases selectivity in micellar liquid chromatography. | The paper describes a new test designed in micellar LC (MLC) to compare the commercial C18 stationary phase properties. This test provides the total hydrophobicity, hydrophilicity, steric selectivity, hydrogen bonding, and ion-exchange capacity properties calculation of the ODS stationary phases. Both the test compound... | ['Chromatography, High Pressure Liquid', 'Cluster Analysis', 'Hydrogen Bonding', 'Hydrogen-Ion Concentration', 'Hydrophobic and Hydrophilic Interactions', 'Ion Exchange', 'Metals', 'Micelles', 'Molecular Conformation', 'Organic Chemicals', 'Pentanols', 'Silica Gel', 'Silicon Dioxide', 'Sodium Dodecyl Sulfate'] | 19,399,863 | [['E05.196.181.400.300'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G02.282'], ['G02.300'], ['G02.409'], ['G02.437'], ['D01.552'], ['D05.374', 'D26.255.560'], ['G02.111.570.820'], ['D02'], ['D02.033.415.640', 'D10.289.640'], ['D01.837.725.700.379', 'D20.280.320.687', 'D26.255.165.320.687'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genomic organization, sequence divergence, and recombination of feline immunodeficiency virus from lions in the wild. | BACKGROUND: Feline immunodeficiency virus (FIV) naturally infects multiple species of cat and is related to human immunodeficiency virus in humans. FIV infection causes AIDS-like disease and mortality in the domestic cat (Felis catus) and serves as a natural model for HIV infection in humans. In African lions (Panthera... | ['Animals', 'Animals, Wild', 'Base Sequence', 'Evolution, Molecular', 'Genes, env', 'Genetic Variation', 'Genome, Viral', 'Humans', 'Immunodeficiency Virus, Feline', 'Lentivirus', 'Lions', 'Phylogeny', 'Recombination, Genetic', 'Species Specificity'] | 18,251,995 | [['B01.050'], ['B01.050.050.300'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.364.875.172', 'G05.360.340.358.024.875.172', 'G05.360.340.358.840.500.172'], ['G05.365'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.82... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The greyhound dog as a model for studying pressure ulcers. | Because of their angular conformation, short hair, and thin skin, greyhounds are particularly subject to development of pressure ulcers. Greyhounds, therefore, can serve as a model to study pressure ulcers, either naturally occurring pressure ulcers or induced dermal pressure lesions. A method for inducing dermal press... | ['Animals', 'Casts, Surgical', 'Disease Models, Animal', 'Dogs', 'Pressure', 'Pressure Ulcer', 'Thromboxane B2'] | 8,318,156 | [['B01.050'], ['E07.858.442.660.430.500', 'E07.858.690.725.430.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.374.715'], ['C17.800.893.665'], ['D10.251.355.255.100.825.810', 'D10.251.355.310.166.971.810']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Practice characteristics and service provision rates of dental hygienists in Australia. | INTRODUCTION: Dental hygienists (DHs) have been practising in Australia since the early 1970s.OBJECTIVE: This study describes the clinical activity of Australian DHs.METHODS: A questionnaire was mailed to members of two professional associations representing DHs. Practitioner characteristics, employment characteristics... | ['Adult', 'Australia', 'Dental Hygienists', 'Dental Prophylaxis', 'General Practice, Dental', 'Humans', 'Middle Aged', 'Orthodontics', 'Periodontics', 'Preventive Dentistry', 'Private Sector', 'Professional Practice Location', 'Public Sector', 'Surveys and Questionnaires', 'Workforce'] | 28,809,084 | [['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.526.485.067.105.376', 'N02.360.067.105.376'], ['E06.721.189', 'E06.761.227'], ['H02.163.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E06.658', 'H02.163.876.439'], ['E06.721', 'H02.163.876.623'], ['E06.761', 'H02.163.721'], ['I... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Frequent detection of bovine polyomavirus in commercial batches of calf serum by using the polymerase chain reaction. | Twenty commercial batches of calf serum, obtained from several suppliers, were tested for the presence of bovine polyomavirus (BPyV) DNA and antibodies against the virus. Using polymerase chain reaction (PCR) technology, BPyV DNA was detected in 70% of the batches; no BPyV was detected in any of the negative control sa... | ['Animals', 'Antibodies, Viral', 'Base Sequence', 'Cattle', 'DNA, Viral', 'Fluorescent Antibody Technique', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Polyomavirus'] | 1,658,200 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.568'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Functional integrity of the central and sympathetic nervous systems is a prerequisite for pressor and tachycardic effects of diphenyleneiodonium, a novel inhibitor of nitric oxide synthase. | The pressor and tachycardic effects of diphenyleneiodonium (DPI), a novel inhibitor of endothelial nitric oxide synthase with chemical structure different from those of NG-substituted Arg analogs, were studied in pentobarbital-anesthetized rats. Bolus injections of DPI (0.05-1.6 mg/kg i.v.) caused transient (1-2 min in... | ['Amino Acid Oxidoreductases', 'Animals', 'Blood Pressure', 'Cardiovascular System', 'Catecholamines', 'Central Nervous System', 'Decerebrate State', 'Heart Rate', 'Nitric Oxide Synthase', 'Onium Compounds', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord', 'Sympathetic Nervous System', 'Tachycardia', 'Tetrodotoxin'] | 7,682,612 | [['D08.811.682.664.500'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['A08.186'], ['C10.597.305', 'C23.888.592.298'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D08.811.682.664.500.772'], ['D02.675'], ['B01.050.150.900.649.313.992.635.505.700... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Co-localization of honeycomb golgi and ACTH granules in a giant ACTH-producing pituitary adenoma. | We document the co-localization of honeycomb golgi and ACTH-immunopositive granules in giant ACTH-producing pituitary adenoma cells. A 42-yr-old woman presented with Cushing's disease and a giant adenoma that invaded the sphenoid and cavernous sinus. She underwent transsphenoidal surgery followed by radiation therapy. ... | ['Adenoma', 'Adrenocorticotropic Hormone', 'Adult', 'Female', 'Golgi Apparatus', 'Humans', 'Magnetic Resonance Imaging', 'Microscopy, Electron, Transmission', 'Pituitary Neoplasms', 'Secretory Vesicles', 'Treatment Outcome'] | 16,299,407 | [['C04.557.470.035'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['A11.284.430.214.190.875.336'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anterior cruciate ligament reconstruction does not induce further gamma loop abnormalities on the intact side of the quadriceps femoris: A longitudinal study. | This study aimed to investigate the effect of surgery on the gamma loop of the quadriceps on the side with an intact knee in patients with anterior cruciate ligament (ACL) injuries. We compared longitudinally the response of alpha motor neurons to vibration stimulation of the quadriceps on the side with an intact knee ... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament Injuries', 'Anterior Cruciate Ligament Reconstruction', 'Electromyography', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Motor Neurons', 'Quadriceps Muscle', 'Vibration', 'Young Adult'] | 28,378,501 | [['M01.060.057'], ['M01.060.116'], ['C26.558.554.213'], ['E04.555.110.026', 'E04.680.101.026'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['A08.675.655.500', 'A11.671.655.500'], ['A0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A prospective study of factors predicting clinically occult spinal cord compression in patients with metastatic prostate carcinoma. | BACKGROUND: The objective of this study was to identify clinical parameters that predict occult subarachnoid space or spinal cord (SAS/SC) compression, as determined by magnetic resonance imaging (MRI), in patients with metastatic prostate carcinoma.METHODS: A prospective study was performed in which 68 patients with b... | ['Aged', 'Aged, 80 and over', 'Bone Neoplasms', 'Carcinoma', 'Diagnosis, Differential', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Physical Examination', 'Predictive Value of Tests', 'Prospective Studies', 'Prostatic Neoplasms', 'Radionuclide Imaging', 'Risk Factors', 'Spinal Cord Compres... | 11,466,683 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.149', 'C05.116.231'], ['C04.557.470.200'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.600'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Graves' disease in pregnancy: prospective evaluation of a selective invasive treatment protocol. | OBJECTIVE: Graves' disease in pregnancy carries a risk of fetal thyrotoxicosis from the transplacental transfer of thyroid-stimulating antibodies or fetal hypothyroidism from transplacental transfer of antithyroid drugs and thyroid-blocking antibodies.STUDY DESIGN: From 1991 through 2002, all pregnant women with Graves... | ['Amniotic Fluid', 'Antithyroid Agents', 'Autoantibodies', 'Blood Specimen Collection', 'Female', 'Fetal Blood', 'Fetal Diseases', 'Follow-Up Studies', 'Graves Disease', 'Humans', 'Hyperthyroidism', 'Hypothyroidism', 'Immunoglobulins, Thyroid-Stimulating', 'Pregnancy', 'Pregnancy Complications', 'Receptors, Thyrotropin... | 12,861,156 | [['A12.098', 'A16.378.149'], ['D06.347.100', 'D27.505.696.399.450.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['C13.703.277', 'C16.300'], ['E05.318.372.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A mixed choroid plexus papilloma and ependymoma. | We report a novel case of a mixed choroid plexus papilloma (CPP) and ependymoma with cartilaginous differentiation. This kind of mixed tumor has not been previously reported in the English literature. The patient was a 5-year-old girl, who presented with a 1-week history of fever and numbness of the right lower limb. M... | ['Brain Neoplasms', 'Cerebral Ventricles', 'Child, Preschool', 'Ependymoma', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Neoplasms, Multiple Primary', 'Neuroimaging', 'Papilloma, Choroid Plexus', 'Treatment Outcome'] | 26,670,168 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A08.186.211.140'], ['M01.060.406.448'], ['C04.557.465.625.600.380.290', 'C04.557.470.670.380.290', 'C04.557.580.625.600.380.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.40... | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Considerations on the use of the construct "Quality of life" as a goal variable in clinical research]. | In recent years the importance of the assessment of quality of life increased, especially in palliative therapy. Commonly used concepts of quality of life comprise of several dimensions, e.g. somatic disorders, functional status, well-being and social interaction. We developed an 18-item questionnaire, self-administere... | ['Adult', 'Aged', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Personal Satisfaction', 'Quality of Life', 'Renal Dialysis', 'Research', 'Surveys and Questionnaires'] | 1,646,477 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['F01.145.677'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Autologous cell therapies: challenges in US FDA regulation. | Cell-based therapies (CBTs) have been hailed for the last two decades as the next pillar of healthcare, yet the clinical and commercial potential of regenerative medicine has yet to live up to the hype. While recent analysis has suggested that regenerative medicine is maturing into a multibillion dollar industry, examp... | ['Cell- and Tissue-Based Therapy', 'Drug Industry', 'Humans', 'Social Control, Formal', 'Transplantation, Autologous', 'United States', 'United States Food and Drug Administration'] | 23,210,819 | [['E02.095.147'], ['J01.576.655.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604', 'N03.706'], ['E04.936.664'], ['Z01.107.567.875'], ['I01.409.418.750.600.650.760', 'N03.540.348.500.500.600.650.760']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Increased prescribing of Valium, Librium, and other drugs--an example of the influence of economic and social factors on the practice of medicine. | Drug prescriptions per capita in the United States have more than doubled since 1950 without a commensurate improvement in health. Drugs are often prescribed for clinical conditions in which therapeutic benefits do not outweigh the risk of adverse drug reactions. Deaths due to adverse drug reactions are roughly as freq... | ['Adult', 'Advertising', 'Aged', 'Anxiety', 'Child', 'Chlordiazepoxide', 'Clinical Trials as Topic', 'Diazepam', 'Drug Evaluation', 'Drug Industry', 'Drug Prescriptions', 'Drug Utilization', 'Economics', 'Female', 'Humans', 'Male', 'Pharmacopoeias as Topic', 'Psychophysiologic Disorders', 'Social Problems', 'United Sta... | 319,068 | [['M01.060.116'], ['J01.219.687.274', 'L01.143.050'], ['M01.060.116.100'], ['F01.470.132'], ['M01.060.406'], ['D03.633.100.079.080.150'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D03.633.100.079.080.070.216'], ['E05.290.625', 'E05.337.425'], ['J01.576.655.750'], ['E02.319.307', '... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Anxiety, depression and coping behaviors with pain in cancer patients who are aware or unaware of their cancer. | OBJECTIVES: This study aimed to investigate whether there are differences in depression, anxiety, pain and styles of coping with pain between cancer patients with and without awareness of their cancer diagnosis.METHODS: In this study, 30 cancer patients aware of their diagnosis and 30 cancer patients unaware of their d... | ['Adaptation, Psychological', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Pain, Intractable', 'Surveys and Questionnaires', 'Visual Analog Scale'] | 29,039,150 | [['F01.058'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['C23.888.592.612.776'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['E01.370.928']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Trochanteric pseudoarthroses after total hip arthroplasty: their fixation with a new claw-plate]. | In the authors experience, non-union of the greater trochanter after its division occurred in 3p. 100 of cases. The treatment is difficult when non-union is well established. The authors have devised an original type of plate whose upper part is made of a double hook to grip the greater trochanter. The lower part of th... | ['Bone Plates', 'Hip Prosthesis', 'Humans', 'Pseudarthrosis'] | 3,562,936 | [['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.404.468.627']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mesenchymal stem cells and endothelial progenitor cells accelerate intra-aneurysmal tissue organization after treatment with SDF-1á-coated coils. | Recurrences of aneurysms remain the major drawback of detachable coils for the endovascular treatment of intracranial aneurysms. The aim of the present study is to develop new modified coils, coating the surface of platinum coils with silk fibroin (SF) consisting of stromal cell-derived factor-1á (SDF-1á), and evaluate... | ['Aneurysm', 'Animals', 'Chemokine CXCL12', 'Coated Materials, Biocompatible', 'Disease Models, Animal', 'Embolization, Therapeutic', 'Endothelial Progenitor Cells', 'Humans', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Microscopy, Electron, Scanning', 'Rats', 'Rats, Sprague-Dawley', 'Time Facto... | 27,125,512 | [['C14.907.055'], ['B01.050'], ['D12.644.276.374.200.120.600', 'D12.776.467.374.200.120.600', 'D23.125.300.120.600', 'D23.469.200.120.600', 'D23.529.374.200.120.600'], ['D25.130.420', 'J01.637.051.130.420'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.520.360', 'E02.926.500'], ['A11.148.174', 'A11.436.275.182'... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The acute medical take: an outpatient specialty. | The traditional model of acute medical care involves the admission of patients to hospital to be assessed by a consultant and facilitate access to investigation and treatment. This model has, however, led to a number of problems. Firstly, there is high bed occupancy which restricts access and increases the risk of heal... | ['Acute Disease', 'Ambulatory Care', 'Emergency Medical Services', 'Health Services Accessibility', 'Humans', 'Medicine', 'Models, Organizational', 'Outpatient Clinics, Hospital', 'Specialization', 'United Kingdom'] | 18,335,662 | [['C23.550.291.125'], ['E02.760.106', 'N02.421.585.106'], ['N02.421.297'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['E05.599.670', 'N04.452.534'], ['N02.278.035.380', 'N02.278.216.500.968.527', 'N04.452.442.452.422.527'], ['H02.811'], ['Z01.542.363']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Recurrent Escherichia coli meningitis associated with aspergillar sphenoidal sinusitis. | Recurrent meningitis due to Escherichia coli is an extremely rare infection in adult patients. Most cases have been complications of neurosurgery. We report on the case of a 43-y-old man with 4 recurrent spontaneous episodes of E. coli meningitis related to aspergillar sphenoidal sinusitis. Surgical treatment of sinusi... | ['Adult', 'Aspergillosis', 'Humans', 'Male', 'Meningitis, Escherichia coli', 'Recurrence', 'Sphenoid Sinusitis'] | 15,307,577 | [['M01.060.116'], ['C01.150.703.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.223.500.350', 'C01.150.252.400.310.330.500', 'C01.207.180.500.350', 'C10.228.228.180.500.350', 'C10.228.614.280.350'], ['C23.550.291.937'], ['C01.748.749.827', 'C08.460.692.752.827', 'C08.730.749.827', 'C09.603.692.752... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Muscular ETB receptors develop postnatally and are differentially distributed in specific segments of the rat vasculature. | The endothelin/endothelin-receptor system is a key player in the regulation of vascular tone in mammals. We raised and characterized an antiserum against rat ETB receptor and investigated the distribution of ETB receptors in different vascular beds during postnatal development (day 0 through day 28) and in the adult ra... | ['Animals', 'Animals, Newborn', 'Blood Vessels', 'Fluorescent Antibody Technique', 'Muscle, Smooth, Vascular', 'Organ Specificity', 'Rats', 'Rats, Wistar', 'Receptor, Endothelin B'] | 15,684,331 | [['B01.050'], ['B01.050.050.282'], ['A07.015'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['G07.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induced pluripotent stem cells (iPSCs) derived from a renpenning syndrome patient with c.459_462delAGAG mutation in PQBP1 (PEIi001-A). | The Renpenning syndrome spectrum is a rare X-linked mental retardation syndrome characterized by intellectual disability, microcephaly, low stature, lean body and hypogonadism. Mutations in the polyglutamine tract binding protein 1 (PQBP1) locus are causative for disease. Here, we describe the generation of an iPSC lin... | ['Base Sequence', 'Cell Line', 'Cerebral Palsy', 'DNA-Binding Proteins', 'Humans', 'Induced Pluripotent Stem Cells', 'Male', 'Mental Retardation, X-Linked', 'Sequence Deletion'] | 31,698,189 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['C10.228.140.140.254'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['C10.597.606.360.455', 'C16.320.322.500', 'C16.320.400.525'], ['G05.365.590.762', 'G05.558.800']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Implementation of a respiratory rehabilitation protocol: weaning from the ventilator and tracheostomy in difficult-to-wean patients with spinal cord injury. | PURPOSE: Following repeated weaning failures in acute care services, spinal cord injury (SCI) patients who require prolonged mechanical ventilation and tracheostomy are discharged to their homes or skilled nursing facilities, with a portable mechanical ventilator (MV) and/or tracheostomy tube (TT) with excess risk of c... | ['Adolescent', 'Adult', 'Aged', 'Clinical Protocols', 'Female', 'Home Care Services', 'Humans', 'Male', 'Middle Aged', 'Patient Discharge', 'Prospective Studies', 'Quality of Life', 'Spinal Cord Injuries', 'Tertiary Care Centers', 'Tracheostomy', 'Turkey', 'Ventilator Weaning', 'Young Adult'] | 27,339,104 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183', 'N05.715.360.330.125'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.169.125', 'E02.760.400.610', 'N02.421.585.169.125', 'N02.421.585.400.610', 'N04.590.233.727.210.125'], ['E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Highly ordered Pb(Zr₀.₅₂ Ti₀.₄₈)O₃ piezoelectric nanorod arrays. | One-dimensional (1D) piezoelectric nanostructures have attracted significant attention for a broad range of applications including optoelectronics, thermoelectrics, electrochemical and electromechanical converters. We demonstrate the synthesis of 1D nanostructures based upon Pb(Zr0.52Ti0.48)O3 (PZT) on conductive subst... | ['Electricity', 'Nanotechnology', 'Nanotubes', 'Oxides', 'Phase Transition', 'Titanium', 'Transducers', 'Zirconium'] | 23,637,024 | [['G01.358.500.249'], ['H01.603', 'J01.897.520.600'], ['J01.637.512.850'], ['D01.248.497.158.685', 'D01.650.550'], ['G01.645', 'G02.734'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['E07.305.812'], ['D01.268.556.950', 'D01.268.956.937', 'D01.552.544.950']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
An In Vitro Study of the Effect of Cytotoxic Triorganotin Dimethylaminophenylazobenzoate Complexes on Red Blood Cells. | Interactions of tributyltin (TBTA) and triphenyltin (TPhTA) 2-[4 (dimethylamino)phenylazo]benzoates, showing promising cytostatic activity against tumor cells, with erythrocytes and with erythrocyte membranes and model lipid membranes have been investigated. The effect of TBTA and TPhTA on the erythrocyte and its model... | ['Animals', 'Cell Membrane', 'Erythrocytes', 'Hemolysis', 'Humans', 'Organotin Compounds', 'Trialkyltin Compounds'] | 30,350,012 | [['B01.050'], ['A11.284.149'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.691.850'], ['D02.691.850.900']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stone cobras: adult bilateral single system ureteroceles presenting with multiple calculi. | 25-year-old previously healthy male presented with dysuria and bilateral flank pain. Abdominal radiography and computed tomography revealed bilateral orthotopic ureteroceles with significant calculi. Bilateral endoscopic ureterocele incision and ureteroscopy were used for complete stone clearance. Symptoms resolved aft... | ['Adult', 'Dysuria', 'Endoscopy', 'Humans', 'Male', 'Radiography', 'Treatment Outcome', 'Ureteral Calculi', 'Ureterocele', 'Ureteroscopy', 'Urinary Calculi'] | 21,334,046 | [['M01.060.116'], ['C23.888.942.343.274'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C12.777.725.938.500', 'C12.777.967.374.500', 'C12.777.967.500.851', 'C13.351.968.725.938.500', 'C13.35... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
"The next best thing": a study of problem gambling. | Traditionally, gamblers whose repeated losses have resulted in serious financial, psychological, and social problems have been labeled "compulsive." The prevailing "illness model" of compulsive gambling was developed by clinicians from the reports of those seeking treatment to stop gambling. However, researchers workin... | ['Compulsive Behavior', 'Counseling', 'Gambling', 'Humans', 'Models, Psychological', 'Public Policy', 'Risk-Taking', 'Self-Help Groups', 'Social Class', 'Social Control, Informal', 'United States'] | 3,833,807 | [['F01.145.527.100'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['F01.145.722.408', 'F03.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['F01.145.722'], ['N03.540.782'], ['I01.880.853.996.755', 'N01.... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Effects of agricultural biodiversity and seasonal rain on dietary adequacy and household food security in rural areas of Kenya. | BACKGROUND: Kenya has a high prevalence of underweight and stunting in children. It is believed that both agricultural biodiversity and seasonal rainfall influences household food security and dietary intake. In the present study we aimed to study the effects of agricultural biodiversity and seasonal rains on dietary a... | ['Biodiversity', 'Child', 'Child Nutritional Physiological Phenomena', 'Child, Preschool', 'Crops, Agricultural', 'Cross-Sectional Studies', 'Diet', 'Energy Intake', 'Family Characteristics', 'Female', 'Food Supply', 'Humans', 'Kenya', 'Male', 'Nutritional Requirements', 'Rural Population', 'Seasons', 'Water Supply'] | 25,909,468 | [['G16.500.275.157.049', 'N06.230.124.049'], ['M01.060.406'], ['G07.203.650.220'], ['M01.060.406.448'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['G07.203.650.240.340'], ['F01.829.263.315', 'I01.240.361', 'I01.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
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