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Impact of demographic changes on the blood supply: Mecklenburg-West Pomerania as a model region for Europe. | BACKGROUND: The population structure in most European countries is currently changing with a shift from younger to older age groups. This study analyzed how demography will determine future blood demand and supply in a well-characterized region.STUDY DESIGN AND METHODS: The population of the main catchment area of the ... | ['Age Distribution', 'Blood Donors', 'Demography', 'Europe', 'Female', 'Germany', 'Health Services Needs and Demand', 'Humans', 'Male', 'Population Dynamics', 'Transplantation'] | 17,319,818 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.898.313'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['Z01.542'], ['Z01.542.315'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['E04.936']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Transmission of a 2009 H1N1 pandemic influenza virus occurs before fever is detected, in the ferret model. | During the early phase of the 2009 influenza pandemic, attempts were made to contain the spread of the virus. Success of reactive control measures may be compromised if the proportion of transmission that occurs before overt clinical symptoms develop is high. In this study we investigated the timing of transmission of ... | ['Animals', 'Body Temperature', 'Disease Models, Animal', 'Disease Outbreaks', 'Ferrets', 'Fever', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza, Human', 'Kinetics', 'Respiratory System', 'Time Factors'] | 22,952,661 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['N06.850.290'], ['B01.050.150.900.649.313.750.250.575.350'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['G... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Admission risk factors for cerebral vasospasm in ruptured brain arteriovenous malformations: an observational study. | INTRODUCTION: Cerebral vasospasm is a well-documented complication of aneurismal subarachnoid hemorrhage but has not been extensively studied in brain arteriovenous malformations (BAVMs). Here, our purpose was to identify risk factors for cerebral vasospasm after BAVM rupture in patients requiring intensive care unit (... | ['Adult', 'Brain', 'Confidence Intervals', 'Female', 'France', 'Glasgow Coma Scale', 'Humans', 'Intensive Care Units', 'Intracranial Arteriovenous Malformations', 'Male', 'Middle Aged', 'Odds Ratio', 'Patient Admission', 'Risk Factors', 'Rupture', 'Ultrasonography', 'Vasospasm, Intracranial'] | 21,831,293 | [['M01.060.116'], ['A08.186.211'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['Z01.542.286'], ['E05.318.308.940.968.875.250', 'E05.944.500', 'N04.452.859.564.800.250', 'N05.715.360.300.715.500.800.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['C10.228.140.300.520... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of Salvia officinalis L. leaves on serum glucose and insulin in healthy and streptozotocin-induced diabetic rats. | The leaves of sage (Salvia officinalis L., Lamiaceae) are reported to have a wide range of biological activities, such as anti-bacterial, fungistatic, virustatic, astringent, eupeptic and anti-hydrotic effects. To determine the hypoglycaemic effect of sage leaves, we investigated the effects of essential oil and methan... | ['Animals', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Hypoglycemic Agents', 'Injections, Intraperitoneal', 'Insulin', 'Lethal Dose 50', 'Male', 'Methanol', 'Oils, Volatile', 'Plant Extracts', 'Plant Leaves', 'Rats', 'Rats, Wistar', 'Salvia', 'Solvents'] | 16,125,023 | [['B01.050'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D27.505.696.422'], ['E02.319.267.530.490'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['D02.033.623'], ['D10.627.675... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcatheter embolization of uterine arteriovenous malformations. | A case of congenital arteriovenous malformation of the uterus in a 25-year-old woman with a long-standing history of recurrent menometrorrhagia is reported. Radiological diagnosis was based on hysterographic, computed tomographic, and angiographic findings. Treatment was performed with percutaneous transcatheter emboli... | ['Adult', 'Angiography', 'Arteriovenous Malformations', 'Embolization, Therapeutic', 'Female', 'Humans', 'Hysterosalpingography', 'Tomography, X-Ray Computed', 'Uterus'] | 3,089,611 | [['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.325', 'E01.370.378.325'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.70... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Crestal bone changes around titanium implants: a methodologic study comparing linear radiographic with histometric measurements. | Generally, endosseous implants can be placed according to a nonsubmerged or a submerged technique and in 1-piece or 2-piece configurations. Recently, it has been shown that peri-implant crestal bone reactions differ significantly radiographically as well as histometrically under such conditions and are dependent on a r... | ['Alveolar Process', 'Analysis of Variance', 'Animals', 'Dental Abutments', 'Dental Implantation, Endosseous', 'Dental Implants', 'Dental Prosthesis Design', 'Dogs', 'Follow-Up Studies', 'Jaw, Edentulous', 'Longitudinal Studies', 'Male', 'Mandible', 'Osseointegration', 'Radiography, Bitewing', 'Reproducibility of Resul... | 11,515,994 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E06.780.346.500', 'E07.695.190.175'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.69... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Salivary tau species are potential biomarkers of Alzheimer's disease. | Phosphorylation of tau protein is a critical event in the pathogenesis of Alzheimer's disease (AD). Increased phosphorylated tau and total tau levels, combined with reduced concentrations of amyloid-â 1-42 (Aâ42) in cerebrospinal fluid (CSF), but not in plasma or serum, have been generally accepted as sensitive AD diag... | ['Adult', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Amino Acid Sequence', 'Biomarkers', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Mass Spectrometry', 'Middle Aged', 'Molecular Sequence Data', 'Pilot Projects', 'Salivary Proteins and Peptides', 'tau Proteins'] | 21,841,250 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D23.101'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.19... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells. | Abscisic acid (ABA) is a plant hormone regulating fundamental physiological functions in plants, such as response to abiotic stress. Recently, ABA was shown to be produced and released by human granulocytes, by insulin-producing rat insulinoma cells, and by human and murine pancreatic beta cells. ABA autocrinally stimu... | ['Abscisic Acid', 'Animals', 'Cell Membrane', 'Cell Movement', 'Cells, Cultured', 'Granulocytes', 'Humans', 'Insulinoma', 'Membrane Proteins', 'N-Glycosyl Hydrolases', 'Nuclear Proteins', 'Phagocytosis', 'Phosphate-Binding Proteins', 'Protein Binding', 'RNA, Small Interfering', 'Rats', 'Reactive Oxygen Species', 'Signa... | 19,667,068 | [['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['B01.050'], ['A11.284.149'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.38... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of carbonic anhydrase isoenzymes in the developing endolymphatic sac of the human fetus and the mouse embryo. | The distribution of carbonic anhydrase isoenzymes (CA) was analyzed in the developing endolymphatic sac (ES) of the mouse embryo and human fetus using immunohistochemical method. The primordial ES epithelium was labelled with CA I and CA II, but was weakly labelled with CA III and CA V. In the thirteenth and fifteenth ... | ['Animals', 'Carbonic Anhydrases', 'Embryonic and Fetal Development', 'Endolymphatic Sac', 'Gestational Age', 'Humans', 'Immunohistochemistry', 'Isoenzymes', 'Mice', 'Mice, Inbred CBA', 'Microscopy, Fluorescence'] | 1,556,501 | [['B01.050'], ['D08.811.520.241.300.150'], ['G07.345.500.325', 'G08.686.784.170'], ['A09.246.300.909.957.360.701'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effective Respiratory CD8 T-Cell Immunity to Influenza Virus Induced by Intranasal Carbomer-Lecithin-Adjuvanted Non-replicating Vaccines. | CD8+ cytotoxic T lymphocytes (CTLs) are critical for clearing many viral infections, and protective CTL memory can be induced by vaccination with attenuated viruses and vectors. Non-replicating vaccines are typically potentiated by the addition of adjuvants that enhance humoral responses, however few are capable of gen... | ['Acrylic Resins', 'Adjuvants, Immunologic', 'Administration, Intranasal', 'Adoptive Transfer', 'Animals', 'CD8-Positive T-Lymphocytes', 'Disease Models, Animal', 'Flow Cytometry', 'Influenza A virus', 'Influenza Vaccines', 'Lecithins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Microscopy, Confocal', 'Orthomyx... | 27,997,610 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['D27.505.696.477.067'], ['E02.319.267.120.655.500'], ['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C22.232', 'E05.5... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Direct visualization of critical hydrogen atoms in a pyridoxal 5'-phosphate enzyme. | Enzymes dependent on pyridoxal 5'-phosphate (PLP, the active form of vitamin B6) perform a myriad of diverse chemical transformations. They promote various reactions by modulating the electronic states of PLP through weak interactions in the active site. Neutron crystallography has the unique ability of visualizing the... | ['Aspartate Aminotransferases', 'Catalysis', 'Catalytic Domain', 'Crystallography', 'Deuterium', 'Dimerization', 'Escherichia coli', 'Hydrogen', 'Neutrons', 'Pyridoxal Phosphate', 'Schiff Bases'] | 29,038,582 | [['D08.811.913.477.700.225'], ['G02.130'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309', 'H01.181.529.240'], ['D01.268.406.500', 'D01.362.340.500', 'D01.496.289'], ['G02.206', 'G03.230'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.268.406', 'D01.362.340'], ['G01.249.660.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimation and prediction for cancer screening models using deconvolution and smoothing. | The model that specifies that cancer incidence, I, is the convolution of the preclinical incidence, g, and the density of time in the preclinical phase, f, has frequently been utilized to model data from cancer screening trials and to estimate such quantities as sojourn time, lead time, and sensitivity. When this model... | ['Clinical Trials as Topic', 'Colorectal Neoplasms', 'France', 'Humans', 'Incidence', 'Mass Screening', 'Models, Statistical', 'Neoplasms', 'Predictive Value of Tests', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Time Factors'] | 11,414,561 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Use of Mpc-amino acids in solid phase peptide synthesis leads to improved coupling efficiencies. | The Mpc-group has a somewhat better stability than the Fmoc-group, resists catalytic hydrogenolysis, is highly stable in acidic media and its elimination product does not polymerize spontaneously. In a direct comparison of coupling efficiencies obtained in solid phase peptide syntheses using Mpc- or Fmoc-amino acids it... | ['Amino Acid Sequence', 'Amino Acids', 'Amino Acids, Sulfur', 'Chemical Phenomena', 'Chemistry', 'Fibrinogen', 'Fluorenes', 'Molecular Sequence Data', 'Molecular Structure', 'Peptide Fragments', 'Peptides', 'Sulfones'] | 1,894,449 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['D02.886.030', 'D12.125.166'], ['G02'], ['H01.181'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D02.455.426.559.847.389', 'D04.615.389'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['D12.644.541'], ['D12.644'], ['D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Response of prostate cancer to anti-Her-2/neu antibody in androgen-dependent and -independent human xenograft models. | Antibody to the Her-2/neu gene product has been shown to inhibit the growth of breast cancer cells overexpressing Her-2/neu and to have clinical utility in treating breast cancer. We studied a recombinant, humanized anti-Her-2/neu antibody (Herceptin) in preclinical models of human prostate cancer. The androgen-depende... | ['Animals', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Mice', 'Mice, Nude', 'Paclitaxel', 'Prostatic Neoplasms', 'Receptor, ErbB-2', 'Transplantation, Heterologous', 'Trastuzumab'] | 10,519,379 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemical and microbial community analysis during aerobic biostimulation assays of non-sulfonated alkyl-benzene-contaminated groundwater. | A chemical and microbial characterization of lab-scale biostimulation assays with groundwater samples taken from an industrial site in which the aquifer had been contaminated by linear non-sulfonate alkyl benzenes (LABs) was carried out for further field-scale bioremediation purposes. Two lab-scale biodegradability ass... | ['Aerobiosis', 'Alkanesulfonic Acids', 'Bacteria, Aerobic', 'Biodegradation, Environmental', 'Colony Count, Microbial', 'Hydrocarbons', 'Petrolatum', 'Water Microbiology', 'Water Pollutants, Chemical', 'Water Pollution, Chemical'] | 20,714,718 | [['G02.111.017', 'G03.049'], ['D02.455.326.146.100', 'D02.886.645.600.055'], ['B03.120'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D02.455'], ['D02.455.699'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['D27.888.284.903.655'], ['N06.850.460.790.410']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Hair cell loss and regeneration after exposure to intense sound in neonatal chicks. | Neonatal chicks (between 1 and 3 days of age) were exposed to an intense pure tone for 48 hours, then killed immediately after removal from the sound, or 14 days later. Nonexposed age-matched animals served as controls. The inner ear was removed and the auditory receptor organ (the basilar papilla) was prepared for eva... | ['Animals', 'Animals, Newborn', 'Chickens', 'Epithelium', 'Hair Cells, Auditory', 'Labyrinth Diseases', 'Organ of Corti', 'Regeneration', 'Sensory Receptor Cells', 'Sound'] | 3,138,621 | [['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A10.272'], ['A08.675.650.250', 'A08.675.650.915.750.600.350', 'A08.800.950.750.600.350', 'A09.246.300.246.577.325', 'A11.671.650.250', 'A11.671.650.915.750.600.350'], ['C09.218.568'], ['A09.246.300.246.577'], ['G16.762'... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using survival analysis to study spatial point patterns in geographical epidemiology. | The spatial K-function has become a well accepted method of investigating whether significant clustering can be detected in spatial point patterns. Unlike nearest neighbor-based methods, the K-function approach has the advantage of exploring spatial pattern across a range of spatial scales. However, K-functions still h... | ['Accidents, Traffic', 'Cluster Analysis', 'England', 'Geography', 'Humans', 'Laryngeal Neoplasms', 'Lung Neoplasms', 'Poisson Distribution', 'Survival Analysis'] | 10,714,921 | [['N06.850.135.392'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['Z01.542.363.300'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E0... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
A model describing nonlinearities in hearing by active processes with saturation at 40 dB. | Data from literature related to nonlinearities of the peripheral part of the hearing system are collected and extended by results from measurements of acoustical responses, masking, cubic difference tones and Zwicker tones. The data indicate 40 dB as a significant value for the dynamic range in neurophysiology as well ... | ['Auditory Fatigue', 'Basilar Membrane', 'Cochlea', 'Cochlear Nerve', 'Hair Cells, Auditory', 'Hearing', 'Models, Biological', 'Models, Neurological', 'Nerve Fibers', 'Noise', 'Psychoacoustics', 'Sound'] | 526,486 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Medication adverse events: Impact of pharmaceutical consultations during the hospitalization of patients]. | The medication iatrogenic events are responsible for nearly one iatrogenic event in five. The main purpose of this prospective multicenter study is to determine the effect of pharmaceutical consultations on the occurrence of medication adverse events during hospitalization (MAE). The other objectives are to study the i... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Drug-Related Side Effects and Adverse Reactions', 'Female', 'Home Care Services', 'Hospitalization', 'Humans', 'Iatrogenic Disease', 'Infant', 'Male', 'Medication Therapy Management', 'Middle Aged', 'Patients', 'Pharmacists', 'Pharmacy S... | 25,438,655 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['C25.100'], ['N02.421.143.524', 'N02.421.539.089'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.875'], ['M01.060.703'], ['N02.421.668.438', 'N03.... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Diagnostic and prognostic implications of the PAX8-PPARã translocation in thyroid carcinomas-a TMA-based study of 226 cases. | AIMS: Follicular thyroid carcinoma (FTC) has been a diagnostic challenge for decades. The PAX8-PPARã rearrangement has been detected in FTC and classic papillary thyroid carcinomas (PTCs). The aims of this study were to assess the presence of PAX8-PPARã by using tissue microarrays in a large cohort of different thyroid... | ['Adenocarcinoma, Follicular', 'Adenoma', 'Carcinoma', 'Carcinoma, Papillary', 'Humans', 'In Situ Hybridization, Fluorescence', 'Kaplan-Meier Estimate', 'Lymphatic Metastasis', 'Neoplasm Invasiveness', 'Oncogene Proteins, Fusion', 'PAX8 Transcription Factor', 'PPAR gamma', 'Paired Box Transcription Factors', 'Prognosis... | 23,738,683 | [['C04.557.470.200.025.060'], ['C04.557.470.035'], ['C04.557.470.200'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350',... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Determining the accuracy of the Canadian Hospitals Injury Reporting and Prevention Program for the representation of the rates of mild traumatic brain injuries in Quebec. | INTRODUCTION: The recent rise in mild traumatic brain injuries (mTBI) in the pediatric population has been documented by many studies in Canada and the United States. The objective of our study was to compare mTBI rates from the Canadian Hospital Injury Reporting and Prevention Program (CHIRPP) in Montr?al with populat... | ['Adolescent', 'Brain Concussion', 'Child', 'Child, Preschool', 'Cities', 'Data Accuracy', 'Female', 'Hospitals, Urban', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Mathematical Concepts', 'Quebec', 'Retrospective Studies', 'Trauma Centers'] | 31,729,311 | [['M01.060.057'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['M01.060.406'], ['M01.060.406.448'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['E05.318.308.028', 'E05.318.370.725.250', 'L01.399.250.202', 'N05.71... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
A method for the isolation of specific tRNA precursors. | tRNA affinity chromatography, based on complex formation between tRNAs with complementary anticodons, has been applied to the isolation of specific tRNA precursors. When [32P]RNA, isolated from an Escherichia coli strain containing a thermolabile ribonuclease P, was chromatographed on resin-bound yeast phenylalanine tR... | ['Base Sequence', 'Chromatography, Affinity', 'Escherichia coli', 'Glutamates', 'Oligoribonucleotides', 'Pancreas', 'RNA, Transfer', 'Ribonucleases'] | 1,108,001 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.170'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.125.067.625', 'D12.125.119.409'], ['D13.695.578.424.500'], ['A03.734'], ['D13.444.735.757'], ['D08.811.277.352.700']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of the high-approach versus low-approach motivational positive affect on the processing stage of cognitive control: an event-related potential study. | The present study used the event-related potentials to investigate the effect of task-irrelevant, high-approach versus low-approach motivational positive affect on proactive and reactive control, and their neural mechanisms. A cue stimulus and a probe stimulus were presented successively in each trial. Participants wer... | ['Adult', 'Cognition', 'Contingent Negative Variation', 'Cues', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Humans', 'Male', 'Motivation', 'Photic Stimulation', 'Reaction Time', 'Young Adult'] | 29,112,677 | [['M01.060.116'], ['F02.463.188'], ['G07.265.216.500.250', 'G11.561.200.500.250'], ['F02.463.425.234'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Posttraumatic Stress Symptoms and Their Association With Smoking Outcome Expectancies Among Homeless Smokers in Boston. | INTRODUCTION: Cigarette smoking and traumatic life experiences are each common among homeless adults, but the prevalence and correlates of posttraumatic stress disorder (PTSD) symptoms among homeless smokers are not known. We assessed symptoms of PTSD and their association with smoking outcome expectancies in a sample ... | ['Adult', 'Boston', 'Female', 'Homeless Persons', 'Humans', 'Male', 'Middle Aged', 'Smokers', 'Smoking', 'Stress Disorders, Post-Traumatic'] | 26,508,393 | [['M01.060.116'], ['Z01.107.567.875.550.510.210', 'Z01.433.210'], ['M01.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.808'], ['F01.145.805'], ['F03.950.750.500']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Super-resolution microscopy localizes perilipin 5 at lipid droplet-mitochondria interaction sites and at lipid droplets juxtaposing to perilipin 2. | OBJECTIVE: Intramyocellular lipid droplets (LD) and their coat proteins PLIN2 and PLIN5 are involved in lipolysis, with a putative role for PLIN5 in mitochondrial tethering. Reportedly, these proteins co-localize and cover the surface of the LD. To provide the spatial basis for understanding how these proteins possess ... | ['Adult', 'Animals', 'Healthy Volunteers', 'Humans', 'Lipid Droplets', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Mitochondria, Muscle', 'Muscle, Skeletal', 'Perilipin-2', 'Perilipin-5', 'Rats'] | 30,591,149 | [['M01.060.116'], ['B01.050'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.393'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630'], ['A11.284.430.214.190.875.564.627', 'A11.284.835.626.627'], ['A02.633.567', 'A10.690.552.500'], ['D12.776.157.464.... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
New NIH Regulations Say Most Basic Human Brain Research Is a Clinical Trial. | New NIH definitions classify virtually all human brain and behavioral research as clinical trials. The new definitions will change regulatory, reporting, and funding schemes for noninvasive studies such as neuroimaging. Resulting burdens threaten the viability of basic biobehavioral science research. | ['Behavioral Research', 'Clinical Trials as Topic', 'Humans', 'National Institutes of Health (U.S.)', 'Neurosciences', 'Social Control, Formal', 'United States'] | 28,919,174 | [['F04.096.144', 'H01.770.644.108'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.409.418.750.600.650.496', 'N03.540.052.750', 'N03.540.348.500.500.600.650.496'], ['H01.158.610'], ['I01.880.604', 'N03.706'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Gliomatosis cerebri in a patient with Ollier disease. | Gliomatosis cerebri (GC) is an uncommon brain tumour defined as a diffuse neoplastic glial cell infiltration of the brain, involving more than two cerebral lobes and, occasionally, the infratentorial structures or the spinal cord. GC of the oligodendroglial phenotype is extremely rare, especially in the paediatric sett... | ['Adolescent', 'Brain Neoplasms', 'Enchondromatosis', 'Humans', 'Male', 'Neoplasms, Neuroepithelial'] | 21,868,231 | [['M01.060.057'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C05.116.099.708.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.600', 'C04.557.470.670', 'C04.557.580.625.600']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Morphometric identification of luminal narrowing of myocardial capillaries after cardioplegic arrest. | BACKGROUND: Because there is no smooth muscle cell surrounding the capillary endothelial cells, the effect of coronary microcirculation at the capillary level following cardioplegic arrest and reperfusion would be much different from that of resistant arterioles. We therefore studied the effect of hypothermic blood car... | ['Adolescent', 'Adult', 'Aged', 'Capillaries', 'Cardiopulmonary Bypass', 'Child', 'Constriction, Pathologic', 'Coronary Vessels', 'Female', 'Heart Arrest, Induced', 'Humans', 'Hypothermia, Induced', 'Male', 'Microcirculation', 'Middle Aged', 'Myocardial Reperfusion'] | 11,216,755 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A07.015.461.165'], ['E04.292.413'], ['M01.060.406'], ['C23.300.287'], ['A07.015.114.269', 'A07.015.908.194'], ['E04.100.376.374', 'E04.928.220.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['G09.330.100.645'], ['M01.060.116.630'], ['E0... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Electrophoresis in gel channels. | We describe a novel approach to generate dynamic pH gradients suited to fractionate or purify samples of biomolecules or particles such as proteins and viruses in tiny volumes. The method combines diffusion and electromigration between micro-scaled channels embedded in hydrogel. For the used geometry and in accordance ... | ['Buffers', 'Electrophoresis, Agar Gel', 'Hydrogen-Ion Concentration', 'Mathematics', 'Microchemistry'] | 15,948,218 | [['D27.720.470.280'], ['E05.196.401.153', 'E05.301.300.100'], ['G02.300'], ['H01.548'], ['E05.196.620', 'H01.181.650']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell death processes during expression of hybrid lethality in interspecific F1 hybrid between Nicotiana gossei Domin and Nicotiana tabacum. | Hybrid lethality, a type of reproductive isolation, is a genetically controlled event appearing at the seedling stage in interspecific hybrids. We characterized the lethality of F(1) hybrid seedlings from Nicotiana gossei Domin and Nicotiana tabacum cv Bright-Yellow 4 using a number of traits including growth rate, mic... | ['Apoptosis', 'DNA, Plant', 'Gene Expression Regulation, Plant', 'Genetic Markers', 'Hybrid Vigor', 'Hydrogen Peroxide', 'Hypocotyl', 'Oxidative Stress', 'Plant Roots', 'Reactive Oxygen Species', 'Superoxides', 'Temperature', 'Time Factors', 'Tobacco'] | 12,481,061 | [['G04.146.954.035'], ['D13.444.308.435'], ['G05.308.375'], ['D23.101.387', 'G05.695.450'], ['G05.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['A18.024.875.750', 'A18.024.937.249', 'A18.550.500'], ['G03.673', 'G07.775.750'], ['A18.400'], ['D01.339.431', 'D01.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
MAGE-C1/CT7 and MAGE-C2/CT10 are frequently expressed in multiple myeloma and can be explored in combined immunotherapy for this malignancy. | The exact function of MAGE-C1/CT7 and MAGE-C2/CT10 is not yet understood in multiple myeloma (MM). However, the homologs MAGE-C1/CT7 and MAGE-C2/CT10 genes encode highly immunogeneic cancer/testis antigens (CTAs) and can be potential targets for T cell-based immunotherapy. MAGE-C1/CT7 and MAGE-C2/CT10 mRNA expression w... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antigens, Neoplasm', 'Biomarkers', 'Female', 'Gene Expression Regulation', 'Humans', 'Immunotherapy', 'Male', 'Middle Aged', 'Multiple Myeloma', 'Neoplasm Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Transcriptome'] | 23,180,015 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.285'], ['D23.101'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['M01.060.116.630'], ['C04.557.595.500', 'C14.907.454.460', 'C15.378.147.780.650', 'C15.378.463.515.460', 'C20.683.515.845', 'C20.683.780.650']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The stomach's response to unappetizing food: cephalic-vagal effects on gastric myoelectric activity. | The aim of this investigation was to determine the effects of sham feeding food that was perceived as unappetizing on the cephalic-vagal reflex as measured by changes in gastric myoelectric activity. Thirty-eight healthy human participants experienced one of two conditions: (i) an appetizing sham feeding condition in w... | ['Adolescent', 'Adult', 'Appetite', 'Electrophysiology', 'Female', 'Food Preferences', 'Humans', 'Male', 'Reflex', 'Stomach', 'Taste', 'Vagus Nerve'] | 11,298,993 | [['M01.060.057'], ['M01.060.116'], ['F02.830.071', 'G07.203.650.390.070', 'G10.261.390.070'], ['H01.158.344.528', 'H01.158.782.236'], ['F01.145.407.516', 'G07.203.650.353.516'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.376.550.650', 'E01.370.600.550.650', 'F02.830.702', 'G11.561.731'], ['A03.556.875.8... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Intimate partner violence in deviant settings--complex needs of women survivors. | BACKGROUND: Women experiencing intimate violence within deviant settings, including bikie and other gangs and cults, have recently been the focus of research in South Australia. Domestic violence shelters are seeing increasing numbers of these women who are often involved in high risk behaviour and/or situations that p... | ['Battered Women', 'Child', 'Domestic Violence', 'Female', 'Humans', 'Mental Health', 'South Australia', 'Survivors', "Women's Health"] | 17,019,454 | [['M01.975.155'], ['M01.060.406'], ['I01.198.240.856.350', 'I01.880.735.900.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['Z01.639.100.968', 'Z01.678.100.373.968'], ['M01.860'], ['N01.400.900']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Rapid antifungal susceptibility determination for yeast isolates by use of Etest performed directly on blood samples from patients with fungemia. | We prospectively determined the antifungal susceptibility of yeast isolates causing fungemia using the Etest on direct blood samples (195 prospectively collected and 133 laboratory prepared). We compared the Etest direct (24 h of incubation) with CLSI M27-A3 and the standard Etest methodologies for fluconazole, voricon... | ['Antifungal Agents', 'Diagnostic Errors', 'Fungemia', 'Humans', 'Microbial Sensitivity Tests', 'Yeasts'] | 20,392,904 | [['D27.505.954.122.136'], ['E01.354', 'N02.421.450.280'], ['C01.150.703.492.594', 'C01.757.360', 'C23.550.470.790.500.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B01.300.930']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Retinopathy of prematurity: the influence of gestational age and retinal maturity on the statistical behavior of risk factors. | The clinical and laboratory data on 140 premature infants, 74 cases with retinopathy of prematurity (ROP) and 66 control cases without ROP, were correlated with ROP grades of increasing severity. By using multiple linear regression (MLR), it is shown that for predicting ROP grades the importance of certain variables va... | ['Gestational Age', 'Humans', 'Hypercapnia', 'Infant, Newborn', 'Oxygen', 'Regression Analysis', 'Retina', 'Retinopathy of Prematurity', 'Risk'] | 3,753,693 | [['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['M01.060.703.520'], ['D01.268.185.550', 'D01.362.670'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['A09.371.729'], ['C11.768.836', 'C16.614.521.731'], ['E05.318.740.600.800', 'G17... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High-administered activity In-111 octreotide therapy with concomitant radiosensitizing 5FU chemotherapy for treatment of neuroendocrine tumors: preliminary experience. | INTRODUCTION: High-administered activity In-111 octreotide (HA-Oc) therapy has been used for patients with disseminated neuroendocrine tumors (NET) with high somatostatin receptor (SSR) expression. Combining HA-Oc with radiosensitizing 5-fluorouracil (5FU) chemotherapy could enhance efficacy. Our other aim was to asses... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Cohort Studies', 'Female', 'Fluorouracil', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Indium Radioisotopes', 'Male', 'Middle Aged', 'Neuroendocrine Tumors', 'Octreotide', 'Radiation-Sensitizing Agents', 'Radiopharmaceuticals', ... | 19,877,882 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D03.383.742.698.875.404'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.496.749.460'], ['M01.060.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Separation and detection of rare cells in a microfluidic disk via negative selection. | Cyto-analysis of rare cells often requires separation and detection with each procedure posing substantial challenges. This paper presents a disk-based microfluidic platform for both procedures via an immunomagnetic negative selection process. The microfluidic platform's unique features include a multistage magnetic gr... | ['Antibodies, Monoclonal', 'Cell Line, Tumor', 'Humans', 'Immunomagnetic Separation', 'Jurkat Cells', 'Keratins', 'Leukocyte Common Antigens', 'Leukocytes', 'Microfluidic Analytical Techniques'] | 21,088,774 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.437', 'E05.200.500.363.441', 'E05.242.363.441'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567.569.440'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ShearWave elastography of fetal lungs in pregnant baboons. | PURPOSE: The purpose of this study was to evaluate the feasibility and reproducibility of transabdominal ShearWave elastography of fetal lungs in pregnant baboons.MATERIALS AND METHODS: During a 9-month period (03/2013-12/2013), two operators prospectively performed ultrasound examinations of fetal lung in pregnant bab... | ['Animals', 'Elasticity Imaging Techniques', 'Feasibility Studies', 'Female', 'Fetus', 'Lung', 'Papio', 'Pregnancy', 'Reproducibility of Results', 'Ultrasonography, Prenatal'] | 27,085,721 | [['B01.050'], ['E01.370.350.850.270'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['A16.378'], ['A04.411'], ['B01.050.150.900.649.313.988.400.112.199.120.610'], ['G08.686.784.769'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E01.370.350.850... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Urea transport in freshly isolated and cultured cells from rat inner medullary collecting duct. | Regulation of urea transport by vasopressin in inner medullary collecting duct (IMCD) cells is thought to be important for the urinary concentrating mechanism. Isolated tubule perfusion studies suggest the existence of a saturable urea carrier. We have measured 14C-urea efflux in IMCD cells which were freshly isolated ... | ['Animals', 'Biological Transport', 'Cells, Cultured', 'Cyclic AMP', 'Female', 'Kidney Medulla', 'Kinetics', 'Osmosis', 'Rats', 'Rats, Inbred Strains', 'Urea', 'Vasopressins'] | 2,172,546 | [['B01.050'], ['G03.143'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A05.810.453.466'], ['G01.374.661', 'G02.111.490'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of RF heating on hip joint implant in phantom during MRI examinations. | PURPOSE: We evaluate radiofrequency (RF) heating of two kinds of hip joint implants of different sizes, shapes and materials. Temperature rises at various positions of each implant are measured and compared with a computer simulation based on electromagnetic-field analysis.METHODS: Two kinds of implants made of cobalt-... | ['Chromium Alloys', 'Hip Prosthesis', 'Hot Temperature', 'Magnetic Resonance Imaging', 'Phantoms, Imaging', 'Prostheses and Implants', 'Radio Waves', 'Titanium'] | 20,702,992 | [['D01.220.175', 'D01.552.033.182', 'D25.058.224', 'D25.339.208.224', 'J01.637.051.058.224', 'J01.637.051.339.208.224'], ['E07.695.400.400'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['E01.370.350.825.500'], ['E07.671'], ['E... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Multiple P2Y receptors mediate contraction in guinea pig mesenteric vein. | Vasoconstrictor responses to exogenous adenine and pyrimidine nucleotides were measured in endothelium-denuded segments of guinea pig mesenteric vein and compared with responses in mesenteric artery. The rank order of potency for nucleotides in veins was: 2-MeSADP = 2-MeSATP > UTP > ATPgammaS = alpha,betaMeATP > UDP = ... | ['Adenine Nucleotides', 'Adenosine Diphosphate', 'Adenosine Triphosphate', 'Animals', 'Guinea Pigs', 'In Vitro Techniques', 'Male', 'Mesenteric Artery, Inferior', 'Mesenteric Veins', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Potassium Chloride', 'Purinergic P2 Receptor Antagonists', 'Pyridoxal Phosphate', 'Pyr... | 10,974,420 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['B01.050.150.900.649.313.992.550'], ['E05.481'], ['A07.015.114.565.510'], ['A07.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A dynamical system perspective to understanding badminton singles game play. | By altering the task constraints of cooperative and competitive game contexts in badminton, insights can be obtained from a dynamical systems perspective to investigate the underlying processes that results in either a gradual shift or transition of playing patterns. Positional data of three pairs of skilled female bad... | ['Acceleration', 'Athletic Performance', 'Competitive Behavior', 'Cooperative Behavior', 'Distance Perception', 'Female', 'Humans', 'Orientation', 'Psychomotor Performance', 'Racquet Sports', 'Young Adult'] | 24,075,690 | [['G01.482.107'], ['I03.450.642.845.054'], ['F01.145.813.105'], ['F01.145.813.115'], ['F02.463.593.200.390', 'F02.463.593.778.255.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.058.577', 'F02.830.606'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['I03.450.642.845.600'], ['M01.060.116.815']] | ['Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Interaction of Candida albicans with human leukocytes and serum. | A quantitative assay of candidacidal activity based on differential staining of non-viable Candida albicans by methylene blue was developed and applied to studies of leukocytes from normal individuals and patients with fungal and other infections. Serum factors were necessary for optimal phagocytosis of C. albicans but... | ['Blood', 'Candida', 'Child', 'Chronic Disease', 'Eosinophils', 'Female', 'Granuloma', 'Humans', 'Immunity', 'Infections', 'Leukocytes', 'Male', 'Methods', 'Methylene Blue', 'Monocytes', 'Mycoses', 'Neutrophils', 'Peroxidases', 'Phagocytosis', 'Staining and Labeling'] | 4,182,532 | [['A12.207.152', 'A15.145'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['M01.060.406'], ['C23.550.291.500'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['C15.604.515.292', 'C23.550.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450']... | ['Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis of lipid-linked oligosaccharides is dependent on the cell cycle in rat 3Y1 cells. | Synchronized cultures of rat 3Y1 cells, prepared by the density-arrested method, were used to investigate the relationship of N-glycosylation to the cell cycle. Although total cellular proteins were synthesized independently of the cell cycle, the synthesis of membrane-bound proteins was found to be dependent on the ce... | ['Animals', 'Cell Cycle', 'Cell Line', 'Glycosylation', 'Lipids', 'Oligosaccharides', 'Rats'] | 9,133,608 | [['B01.050'], ['G04.144'], ['A11.251.210'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['D10'], ['D09.698.629'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intestinal helminths and their influence on the indicators of iron status in the elderly. | The intestinal helminthiasis and hematological status was assessed in 100 elderly residents of two low-land communities, one at sea-level and the other at 61; m, equally representative of men and women. These are beth low-income communities. The population showed a 48% helminth infection rate which consisted of hookwor... | ['Aged', 'Aged, 80 and over', 'Anemia, Iron-Deficiency', 'Animals', 'Ascariasis', 'Erythrocyte Count', 'Feces', 'Female', 'Ferritins', 'Guatemala', 'Helminthiasis', 'Helminths', 'Hematocrit', 'Hemoglobins', 'Hookworm Infections', 'Humans', 'Intestinal Diseases, Parasitic', 'Intestines', 'Iron', 'Male', 'Middle Aged', '... | 10,995,086 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C15.378.071.196.300', 'C18.452.565.100'], ['B01.050'], ['C01.610.335.508.700.100.070'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.330', 'E05.242.195.107.330', 'G04.140.107.330', 'G09.188.105.330'], ['A12.459'],... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
14-3-3ó attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells. | Rho GDP dissociation inhibitor 2 (RhoGDI2) promotes tumor growth and malignant progression and enhances chemoresistance of gastric cancer. Recently, we noted an inverse correlation between RhoGDI2 and 14-3-3ó expression, which suggests that 14-3-3ó is a target of gastric cancer metastasis and the chemoresistance-promot... | ['14-3-3 Proteins', 'Apoptosis', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'Cell Movement', 'Cisplatin', 'Disease Progression', 'Down-Regulation', 'Drug Resistance, Neoplasm', 'Enzyme Activation', 'Exoribonucleases', 'Extracellular Signal-Regulated MAP Kinases', 'HeLa Cells', 'Humans', 'MAP Kinase Signaling System', 'MC... | 24,185,104 | [['D12.644.360.024.050', 'D12.776.157.057.002', 'D12.776.476.024.050'], ['G04.146.954.035'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['C23.550.291.656'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G07.690.773.984.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differences in food intake and nutritional habits between Spanish adolescents who engage in ski activity and those who do not. | BACKGROUND: Increasing obesity among adolescents in the industrialized world may result from poor nutritional habits and inadequate exercise.AIM: To determine differences in food intake, nutritional habits, and body mass index between Spanish adolescents who engage in ski activity and those who do not.METHODS: A socio-... | ['Adolescent', 'Body Mass Index', 'Child', 'Eating', 'Feeding Behavior', 'Female', 'Humans', 'Male', 'Motor Activity', 'Sex Factors', 'Skiing', 'Socioeconomic Factors', 'Spain', 'Surveys and Questionnaires'] | 25,617,584 | [['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['N05.715.350.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Anterior wedge-shaped bone graft for old scaphoid fractures or non-unions. An analysis of relevant carpal alignment. | For appraisal of anterior wedge-shaped grafts for the humpback deformity of the scaphoid, a retrospective study of 27 cases with old scaphoid fractures or non-unions was carried out. 11 cases were treated with Herbert screw fixation and anterior wedge-shaped graft and the other cases with other methods. For the assessm... | ['Adolescent', 'Adult', 'Bone Transplantation', 'Carpal Bones', 'Female', 'Fracture Healing', 'Fractures, Ununited', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiography', 'Range of Motion, Articular', 'Reoperation', 'Retrospective Studies'] | 7,797,969 | [['M01.060.057'], ['M01.060.116'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['A02.835.232.087.319.150'], ['G16.762.891.500'], ['C26.404.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E01.370.350.700'], ['E01.370.600.700', 'G11.427.760'], ['E04.690'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Recollection of pain due to inappropriate versus appropriate implantable cardioverter-defibrillator shocks. | BACKGROUND: Although inappropriate shocks are known to be an important consequence of implantable cardioverter-defibrillators (ICDs), the subjective experience of pain intensity perceived by those receiving inappropriate versus appropriate shocks has not previously been examined.METHODS: One hundred ICD patients underw... | ['California', 'Comorbidity', 'Defibrillators, Implantable', 'Electric Injuries', 'Equipment Failure', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Pain', 'Risk Assessment', 'Risk Factors'] | 21,077,915 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N05.715.350.225', 'N06.850.490.687'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['C26.324'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375',... | ['Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Relationship between patient safety and hospital surgical volume. | OBJECTIVE: To examine the relationship between hospital volume and in-hospital adverse events.DATA SOURCES: Patient safety indicator (PSI) was used to identify hospital-acquired adverse events in the Nationwide Inpatient Sample database in abdominal aortic aneurysm, coronary artery bypass graft, and Roux-en-Y gastric b... | ['Adult', 'Aged', 'Aortic Aneurysm, Abdominal', 'Coronary Artery Bypass', 'Female', 'Gastric Bypass', 'Health Facility Size', 'Humans', 'Male', 'Middle Aged', 'Patient Safety', 'Retrospective Studies', 'Risk Factors', 'Statistics, Nonparametric', 'Surgery Department, Hospital', 'United States'] | 22,091,561 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['N02.278.306', 'N05.300.430.410'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Identification of lipid components of human serum lipoproteins involved in the inhibition of Sindbis virus infectivity, hemagglutination, and hemolysis. | Human serum high density lipoproteins (HDL), low density lipoproteins (LDL) and very low density lipoproteins (VLDL) were isolated and tested for their ability to inhibit Sindbis virus infectivity, hemagglutination and hemolysis. VLDL and LDL produced a strong reduction on both viral infectivity on Vero cell monolayers... | ['Apoproteins', 'Cholesterol, VLDL', 'Epitopes', 'Female', 'Hemagglutination Inhibition Tests', 'Hemolysis', 'Humans', 'Lipids', 'Lipoproteins, HDL', 'Lipoproteins, LDL', 'Male', 'Neutralization Tests', 'Sindbis Virus', 'Viral Proteins'] | 2,463,824 | [['D12.776.070'], ['D04.210.500.247.808.197.247', 'D10.532.599.700', 'D10.570.938.208.285', 'D12.776.521.622.700'], ['D23.050.550'], ['E01.370.225.812.735.370', 'E05.200.812.735.370', 'E05.478.594.760.370'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['D10.532.432', 'D12.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activity of ciprofloxacin against multiply resistant strains of Pseudomonas aeruginosa, Staphylococcus epidermidis, and group JK corynebacteria. | The susceptibilities of multiply resistant clinical isolates of Pseudomonas aeurginosa to ciprofloxacin, norfloxacin, and several beta-lactam and aminoglycoside antibiotics were evaluated. Ciprofloxacin also was compared with methicillin and vancomycin against methicillin-resistant Staphylococcus epidermidis and group ... | ['Actinomycetales', 'Cefotaxime', 'Ciprofloxacin', 'Gentamicins', 'Humans', 'Methicillin', 'Mezlocillin', 'Microbial Sensitivity Tests', 'Norfloxacin', 'Penicillin Resistance', 'Pseudomonas aeruginosa', 'Staphylococcus epidermidis', 'Ticarcillin', 'Vancomycin'] | 3,101,589 | [['B03.510.024.049'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['D03.633.100.810.835.322.186'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.099.750.500', 'D02.886.108.750.500', 'D03.633.100.300.750.500'], ['D02.065.589.099.750.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Australian songbird body size tracks climate variation: 82 species over 50 years. | The observed variation in the body size responses of endotherms to climate change may be explained by two hypotheses: the size increases with climate variability (the starvation resistance hypothesis) and the size shrinks as mean temperatures rise (the heat exchange hypothesis). Across 82 Australian passerine species o... | ['Adaptation, Physiological', 'Animals', 'Australia', 'Biological Evolution', 'Body Size', 'Climate Change', 'Phenotype', 'Seasons', 'Songbirds', 'Temperature'] | 31,771,472 | [['G07.025', 'G16.012.500'], ['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['G05.045', 'G16.075'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['G16.500.175.374'], ['G05.695'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['B01.050.150.900.248.620.7... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Discovery of novel pyrazolopyrimidinone analogs as potent inhibitors of phosphodiesterase type-5. | Cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type-5 (PDE5), a clinically proven target to treat erectile dysfunction and diseases associated with lower cGMP levels in humans, is present in corpus cavernosum, heart, lung, platelets, prostate, urethra, bladder, liver, brain, and stomach. Sildenafil, v... | ['Animals', 'Cyclic Nucleotide Phosphodiesterases, Type 5', 'Dose-Response Relationship, Drug', 'Drug Discovery', 'Humans', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Molecular Structure', 'Phosphodiesterase 5 Inhibitors', 'Pyrazoles', 'Pyrimidinones', 'Rabbits', 'Structure-Activity Relationship'] | 25,801,159 | [['B01.050'], ['D08.811.277.352.640.150.500', 'D08.811.277.352.640.155.500', 'D12.644.360.008.500', 'D12.644.360.009.500', 'D12.776.476.008.500', 'D12.776.476.009.500'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Antipsychotic drugs inhibit the function of breast cancer resistance protein. | The ABCG2 transporter breast cancer resistance protein (BCRP) has been identified in several physiological sites. It has been suggested to play an important role in disposition of many drugs and environmental toxins. We investigated the effects of several antipsychotic drugs, including risperidone, 9-hydroxy-risperidon... | ['ATP Binding Cassette Transporter, Subfamily G, Member 2', 'ATP-Binding Cassette Transporters', 'Antipsychotic Agents', 'Caco-2 Cells', 'Cell Line, Tumor', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Estrone', 'Flow Cytometry', 'Humans', 'Inactivation, Metabolic', 'Mitoxantrone', 'Neoplasm Proteins', 'Su... | 18,834,354 | [['D12.776.157.530.100.228.500', 'D12.776.395.550.020.457.500', 'D12.776.543.550.192.457.500', 'D12.776.543.585.100.228.500'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['A11.25... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in the microbiota cause genetically modified Anopheles | The mosquito's innate immune system controls both Plasmodium and bacterial infections. We investigated the competitiveness of mosquitoes genetically modified to alter expression of their own anti-Plasmodium immune genes in a mixed-cage population with wild-type mosquitoes. We observed that genetically modified mosquito... | ['Animals', 'Animals, Genetically Modified', 'Anopheles', 'Digestive System', 'Female', 'Gastrointestinal Microbiome', 'Immunity, Innate', 'Malaria', 'Male', 'Mating Preference, Animal', 'Mosquito Control', 'Plasmodium'] | 28,963,254 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['A03'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['G12.450.564'], ['C01.610.752.530', 'C01.920.875'], ['F01.145.113.252.748.300'], ['N06.850.780.200.650.425.500'], ['B01.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Essential role of hemoglobin beta-93-cysteine in posthypoxia facilitation of breathing in conscious mice. | When erythrocyte hemoglobin (Hb) is fully saturated with O2, nitric oxide (NO) covalently binds to the cysteine 93 residue of the Hb â-chain (B93-CYS), forming S-nitrosohemoglobin. Binding of NO is allosterically coupled to the O2 saturation of Hb. As saturation falls, the NO group on B93-CYS is transferred to thiols i... | ['Animals', 'Carotid Sinus', 'Consciousness', 'Cysteine', 'Hemoglobins', 'Hypoxia', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Pulmonary Ventilation', 'Respiratory Mechanics', 'Structure-Activity Relationship'] | 24,610,531 | [['B01.050'], ['A07.015.114.186.456'], ['F02.463.188.409', 'F02.830.233'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D12.776.124.400', 'D12.776.422.316.762'], ['C23.888.852.079'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.... | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vitreous hemorrhage secondary to juxtapapillary vascular hamartoma of the retina. | The authors report an unusual case with vitreous hemorrhage due to a vascular hamartoma of the optic nerve-head and treated by pars plana vitrectomy. Systemic abnormalities included a seizure disorder, periungual fibroma, and intracranial calcifications suggesting systemic tuberous sclerosis. However, the ocular lesion... | ['Adolescent', 'Eye Neoplasms', 'Female', 'Fluorescein Angiography', 'Hemangioma', 'Hemorrhage', 'Humans', 'Retinal Vessels', 'Vitreous Body'] | 6,729,263 | [['M01.060.057'], ['C04.588.364', 'C11.319'], ['E01.370.370.050.350', 'E01.370.380.250'], ['C04.557.645.375'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.611'], ['A09.371.714.500']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effects of coexisting lipids on the action of Bacillus thuringiensis phosphatidylinositol-specific phospholipase C toward liposomal substrate. | The hydrolytic activity of phosphatidylinositol (PI)-specific phospholipase C (PI-PLC) from Bacillus thuringiensis was studied in detail toward mixed liposomes consisting of PI and one of other phospholipids and cholesterol. Among PI-liposomes, small unilamellar vesicles (SUV) were the most sensitive to PI-PLC; the enz... | ['Bacillus thuringiensis', 'Cholesterol', 'Lipids', 'Liposomes', 'Phosphatidylinositols', 'Type C Phospholipases'] | 1,799,944 | [['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D10'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Purification and characterization of digitalislike factors from human plasma. | Increased levels of a humoral inhibitor of active sodium transport have been associated with the response to acute and chronic hypervolemia and various forms of experimental as well as human essential hypertension. In this report, we describe the purification of inhibitors of Na+, K+-adenosine triphosphatase (ATPase) f... | ['4-Nitrophenylphosphatase', 'Blood Proteins', 'Blood Volume', 'Cardenolides', 'Cardiac Glycosides', 'Chromatography, Liquid', 'Digoxin', 'Dose-Response Relationship, Drug', 'Humans', 'Isotonic Solutions', 'Lysophospholipids', 'Membrane Lipids', 'Norepinephrine', 'Ouabain', 'Potassium', 'Saponins', 'Sodium Chloride', '... | 2,824,370 | [['D08.811.277.352.650.575'], ['D12.776.124'], ['G09.188.130', 'G09.330.380.092'], ['D04.210.500.155.580.130'], ['D04.210.500.155.580', 'D09.408.180'], ['E05.196.181.400'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688', 'D09.408.180.261.436'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High prevalence of cardio-metabolic risk factors among adolescents with intellectual disability. | UNLABELLED: Adults with intellectual disabilities (IDs) have poor lifestyle-related health compared with the general population. Our aim was to study whether such differences are present already in adolescents.AIM: To compare the prevalence and severity of cardio-metabolic risk factors and cardio-vascular fitness in ad... | ['Adolescent', 'Age Factors', 'Anthropometry', 'Body Composition', 'Body Mass Index', 'Cardiovascular Diseases', 'Comorbidity', 'Cross-Sectional Studies', 'Female', 'Humans', 'Insulin Resistance', 'Intellectual Disability', 'Lipids', 'Male', 'Physical Fitness', 'Prevalence', 'Risk Factors', 'Sex Factors', 'Sweden', 'Yo... | 19,183,118 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Biological atomism and cell theory. | Biological atomism postulates that all life is composed of elementary and indivisible vital units. The activity of a living organism is thus conceived as the result of the activities and interactions of its elementary constituents, each of which individually already exhibits all the attributes proper to life. This pape... | ['Biology', 'Cell Biology', 'Cells', 'Dissent and Disputes', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'Life'] | 20,934,641 | [['H01.158.273'], ['H01.158.100.433', 'H01.158.273.160'], ['A11'], ['F01.829.401.094', 'F02.463.785.373.476'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.752.400']] | ['Disciplines and Occupations [H]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in microtubule-associated tau protein in human neuroblastoma cells after phencyclidine. | 1. A human neuroblastoma cell line, SH-SY5Y, was used to study the effects of phencyclidine (PCP) on microtubule-associated tau protein, which acts in vivo chiefly to induce the assembly of tubulin and in vitro to promote microtubule polymerization. 2. PCP (1.0 mM) decreased tau protein (50 kD) in the cytoplasmic (supe... | ['Blotting, Western', 'Cell Division', 'Cytoplasm', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Microtubules', 'Neuroblastoma', 'Phencyclidine', 'Tumor Cells, Cultured', 'tau Proteins'] | 1,511,852 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.430.214'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.750.602'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Change in the splenic megakaryocytes of white rats during regeneration under varying conditions]. | Different forms of megakaryocytes are found in the intact spleen of rats, with ring-like nucleus and in the form of multinuclear large cells. The division of megakaryocytes takes place by multipolar mitosis without any subsequent cytotomy. During the regeneration the megakaryocyte count and their mitotic activity displ... | ['Animals', 'Cell Differentiation', 'Gravitation', 'Megakaryocytes', 'Mitosis', 'Rats', 'Regeneration', 'Restraint, Physical', 'Spleen', 'Time Factors'] | 907,831 | [['B01.050'], ['G04.152'], ['G01.060.350'], ['A11.148.479', 'A15.378.316.479'], ['G04.144.220.220.781', 'G05.113.220.781'], ['B01.050.150.900.649.313.992.635.505.700'], ['G16.762'], ['E02.085.700', 'E05.472.760'], ['A10.549.700', 'A15.382.520.604.700'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Macromolecular photoaffinity labeling of the lutropin receptor on granulosa cells. | Lutropin, a pituitary hormone, and human choriogonadotropin bind to the same receptors in the ovary and elicit identical responses. A photoactivable derivative of human choriogonadotropin was used to identify the lutropin receptor on porcine granulosa cells. The hormone was condensed with a heterobifunctional reagent, ... | ['Affinity Labels', 'Animals', 'Binding, Competitive', 'Chorionic Gonadotropin', 'Cross-Linking Reagents', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Granulosa Cells', 'Molecular Weight', 'Receptors, Cell Surface', 'Receptors, LH', 'Swine'] | 6,261,243 | [['D27.720.470.410.080'], ['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D27.720.470.410.210'], ['E05.196.401.402', 'E05.301.300.319'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetics of Vipera aspis venom after experimental envenomation in rabbits. | Toxicokinetic studies of Vipera aspis venom were performed in rabbits after experimental envenomation. Venom proteins with a molecular weight greater than 6 kDa (high-molecular weight proteins) and which reacted in enzyme-linked immunosorbent assay with specific antiviper venom Fab'2, were also responsible for the leth... | ['Animals', 'Biological Availability', 'Chromatography, Gel', 'Enzyme-Linked Immunosorbent Assay', 'Male', 'Mice', 'Proteins', 'Rabbits', 'Viper Venoms'] | 8,138,962 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['E05.196.181.400.250'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776'], ['B01.050.150.900.649.313.968.700'], ['D20.888.850.960', 'D23.946.833.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of sex hormones on immune function: a meta-analysis. | The effects of sex hormones on immune function have received much attention, especially following the proposal of the immunocompetence handicap hypothesis. Many studies, both experimental and correlational, have been conducted to test the relationship between immune function and the sex hormones testosterone in males a... | ['Animals', 'Female', 'Gonadal Steroid Hormones', 'Immunity', 'Male'] | 26,800,512 | [['B01.050'], ['D06.472.334.851'], ['G12.450']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urinary 3H-tetracycline and pyridinium crosslinks differ in their response to calcium restriction in mature and aged rats. | The aim of this study was to evaluate bone resorption (BR) in rats by two methods: chronic 3H-tetracycline labeling (3HTC) and pyridinium crosslink excretion (PYDX), and compare the sensitivity of these markers in two age groups. Female Sprague-Dawley rats at 12-29 weeks of age ("mature", n = 12) and at 40-57 weeks of ... | ['Age Factors', 'Amino Acids', 'Animals', 'Biomarkers', 'Bone Resorption', 'Calcium, Dietary', 'Female', 'Rats', 'Rats, Sprague-Dawley', 'Time Factors'] | 10,089,230 | [['N05.715.350.075', 'N06.850.490.250'], ['D12.125'], ['B01.050'], ['D23.101'], ['C05.116.264', 'G11.427.213.150'], ['D01.146.395'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G01.910.857']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi. | The number of fully sequenced fungal genomes is rapidly increasing. Since genetic tools are poorly developed for most filamentous fungi, it is currently difficult to employ genetic engineering for understanding the biology of these fungi and to fully exploit them industrially. For that reason there is a demand for deve... | ['Aspergillus', 'Base Sequence', 'CRISPR-Cas Systems', 'Escherichia coli', 'Gene Expression Regulation, Fungal', 'Gene Targeting', 'Genetic Engineering', 'Genetic Markers', 'Molecular Sequence Data', 'Mutagenesis', 'Plasmids', 'RNA, Catalytic', 'RNA, Guide', 'Transformation, Genetic'] | 26,177,455 | [['B01.300.381.081'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.203.374.394'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.330'], ['E05.393.335'], ['E05.393.420'], ['D23.101.387', 'G05.695.450'], ['L01.453.245.667'], ['G05.558'], ['G05.360.600'], ['D08.811.797', 'D13.444... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Waist circumference, body mass index and waist to hip ratio for prediction of the metabolic syndrome in Chinese. | BACKGROUND AND AIMS: To explore the ability of waist circumference (WC), body mass index (BMI) and waist to hip ratio (WHR) to predict two or more non-adipose components of the metabolic syndrome (MetS) among individuals aged 18-85 in North China.METHODS AND RESULTS: This study is a cluster sample survey of 101,510 ind... | ['Adolescent', 'Adult', 'Age Distribution', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'Body Mass Index', 'China', 'Female', 'Health Surveys', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Predictive Value of Tests', 'Prevalence', 'ROC Curve', 'Reproducibility of Results',... | 19,188,050 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.252.474.164'], ['E05.31... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A novel HLA-A*02 allele, A*02:436, was identified by sequencing-based typing. | A novel allele A*02:436 was identified in a Chinese individual by sequence-based typing method. | ['Alleles', 'Amino Acid Substitution', 'Asian Continental Ancestry Group', 'Base Sequence', 'Codon', 'Exons', 'Female', 'Genotype', 'HLA-A2 Antigen', 'Hematopoietic Stem Cell Transplantation', 'Histocompatibility Testing', 'Humans', 'Point Mutation', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Tissue Donors'] | 27,102,084 | [['G05.360.340.024.340.030'], ['E05.393.420.601.035', 'G05.558.109'], ['M01.686.508.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['G05.360.340.024.340.137.232'], ['G05.380'], ['D12.776.395.550.489.400.020', 'D12.776.543.550.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42. | In studies of Alzheimer's disease pathogenesis there is an increasing focus on mechanisms of intracellular amyloid-beta (Abeta) generation and toxicity. Here we investigated the inhibitory potential of the 42 amino acid Abeta peptide (Abeta1-42) on activity of electron transport chain enzyme complexes in human mitochon... | ['Amyloid beta-Peptides', 'Animals', 'Brain', 'Cells, Cultured', 'Copper', 'Electron Transport Complex IV', 'Humans', 'Mice', 'Mice, Transgenic', 'Mitochondria', 'Mitochondria, Liver', 'Multiprotein Complexes', 'Peptide Fragments', 'Time Factors'] | 15,659,604 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['A08.186.211'], ['A11.251'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thoracoscopic mapping and cryoablation of right ventricular tachycardia. | A 14-year-old girl with right ventricular dysplasia and recurrent drug refractory ventricular tachycardia underwent thoracoscopic mapping cryoablation. Good access to the right ventricular free wall was obtained. We suggest this technique may have an important role in the management of patients with right ventricular t... | ['Adolescent', 'Catheter Ablation', 'Cryosurgery', 'Electrocardiography', 'Female', 'Heart Conduction System', 'Heart Rate', 'Humans', 'Reoperation', 'Tachycardia, Ventricular', 'Thoracoscopy'] | 11,225,600 | [['M01.060.057'], ['E02.808.750.500', 'E04.014.760.500'], ['E04.014.180'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.409'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.690'], ['C14.280.067.845.940', 'C14.280.123.875.940', 'C23.550.073.845.940'], ['E01.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of preoperative risk factors and complication rates in cosmetic breast surgery. | To assess the relationships between body mass index, smoking, and diabetes and postoperative complications after cosmetic breast surgery, based on patient claims made to CosmetAssure, a program which provides coverage for treatment of significant complications, which might not be reimbursed by patients' health insuranc... | ['Body Mass Index', 'Chi-Square Distribution', 'Diabetes Mellitus', 'Esthetics', 'Female', 'Humans', 'Insurance, Health, Reimbursement', 'Louisiana', 'Mammaplasty', 'Postoperative Complications', 'Prospective Studies', 'Risk Factors', 'Smoking', 'Surgical Wound Infection', 'Treatment Outcome'] | 20,395,806 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C18.452.394.750', 'C19.246'], ['F02.463.785.477', 'K01.752.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Chromosomal translocations and inherited semisterility in the malaria vector Anopheles stephensi Liston. | Anopheles stephensi males were irradiated with 3500 rads of gamma rays at the rate of 140 rads/min to induce chromosomal aberrations. Seven reciprocal translocations were isolated, including four sex-linked and three autosomal. The presence of translocations were confirmed by cytological analysis. | ['Animals', 'Anopheles', 'Cell Line', 'Evaluation Studies as Topic', 'Female', 'Gamma Rays', 'Infertility, Male', 'Male', 'Mitotic Index', 'Mosquito Control', 'Translocation, Genetic'] | 1,344,173 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['A11.251.210'], ['E05.337', 'N05.715.360.335'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['C12.294.365.700'], ['E01.370.225.500.385.500', 'E05.200.500.385.500', 'E05.242.385.500'], ['N06.850.780.200.650.425.500'], ['C23.550.21... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Tibial plateau fractures in alpine skiing--return to the slopes or career end?]. | BACKGROUND: Fractures of the tibial plateau are among the most severe injuries of the knee joint and are often the result of sports accidents, especially skiing accidents.PATIENTS/MATERIALS AND METHODS: Between January 2003 and March 2009, a total of 37 skiers with tibial plateau fractures were treated operatively at K... | ['Adult', 'Aged', 'Female', 'Fracture Fixation, Internal', 'Fracture Healing', 'Humans', 'Knee Injuries', 'Male', 'Middle Aged', 'Recovery of Function', 'Skiing', 'Tibial Fractures', 'Treatment Outcome'] | 24,665,013 | [['M01.060.116'], ['M01.060.116.100'], ['E04.555.300.300'], ['G16.762.891.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['M01.060.116.630'], ['G16.757'], ['I03.450.642.845.787.500'], ['C26.404.875', 'C26.558.857'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Chlorpromazine activates chloride currents in Xenopus oocytes. | Xenopus oocytes are frequently used for in vivo expression of DNA and RNA, especially those encoding ion channel proteins. Accordingly, it is important to understand the expression and control of endogenous conductances. Ionic currents were studied in native Xenopus oocytes with two-microelectrode voltage-clamp techniq... | ['Animals', 'Antipsychotic Agents', 'Calcium', 'Calcium-Transporting ATPases', 'Calmodulin', 'Cell Membrane', 'Chelating Agents', 'Chloride Channels', 'Chlorpromazine', 'Egtazic Acid', 'Enzyme Inhibitors', 'Oocytes', 'Patch-Clamp Techniques', 'Receptors, Dopamine', 'Thapsigargin', 'Trifluoperazine', 'Xenopus'] | 9,059,494 | [['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['D12.644.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of retinol binding protein in multiple-case families with insulin-dependent diabetes. | We performed a family study to investigate the heritability of reduced serum retinol levels observed in type 1 diabetes cases. Diet and serum factors, including retinol, total carotene, malondialdehyde, and retinol binding protein levels, were measured in 11 multiple-case families. The mean serum retinol level of the d... | ['Analysis of Variance', 'Carotenoids', 'Diabetes Mellitus, Type 1', 'Disease Susceptibility', 'Feeding Behavior', 'Humans', 'Linear Models', 'Retinol-Binding Proteins', 'Vitamin A'] | 9,037,897 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C23.550.291.687', 'G07.100.250'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Monitoring for precursors of health impairment from toxic agents. | It is essential that one be able to diagnose when disorders are caused by drugs and toxic agents. It is also essential that scientists strive toward the ultimate goal of preventing such disorders. To this end, it is necessary to evaluate laboratory procedures for their capability to detect changes which precede disorde... | ['Drug-Related Side Effects and Adverse Reactions', 'Heme', 'Humans', 'Lead', 'Lead Poisoning', 'Pharmaceutical Preparations', 'Poisoning'] | 962,295 | [['C25.100'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.435', 'D01.552.544.435'], ['C25.723.522.750'], ['D26'], ['C25.723']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prospective comparison of two gamma probes for intraoperative detection of 18F-FDG: in vitro assessment and clinical evaluation in differentiated thyroid cancer patients with iodine-negative recurrence. | PURPOSE: This study was aimed at evaluating the spatial resolution and sensitivity of two hand-held gamma probes. Radioguided surgery was tested in seven patients with iodine-negative differentiated thyroid cancer (DTC) recurrence using (18)F-FDG PET.METHODS: Two gamma probes were evaluated: Clerad's GammaSup with a co... | ['Adult', 'Aged', 'Female', 'Fluorodeoxyglucose F18', 'Gamma Cameras', 'Humans', 'Intraoperative Care', 'Iodine Radioisotopes', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prospective Studies', 'Radionuclide Imaging', 'Radiopharmaceuticals', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Surger... | 17,522,858 | [['M01.060.116'], ['M01.060.116.100'], ['D09.254.229.500'], ['E07.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E05.318.372.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery. | Herein, reduction-responsive disintegratable nanoclusters (NCs) were prepared as a novel nanovehicle for targeted drug delivery. The NCs, with a diameter of ?170 nm, were self-assembled from hydrophobically modified and iRGD decorated hydroxyethyl starch (iRGD-HES-SS-C18). DOX was loaded into the NCs as a model drug. D... | ['Animals', 'Cell Line, Tumor', 'Doxorubicin', 'Drug Delivery Systems', 'Hep G2 Cells', 'Humans', 'Hydroxyethyl Starch Derivatives', 'Mice', 'Molecular Structure', 'Nanoparticles', 'Oligopeptides'] | 29,799,599 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E02.319.300'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.301.915.500', 'D09.698.365.855.500'], ['B01.050.150.900... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sexual function of undergraduate women: a comparative study between Brazil and Italy. | OBJECTIVE: to evaluate the sexual function of Italian and Brazilian nursing students using the Female Sexual Function Index (FSFI), to estimate the prevalence of sexual dysfunctions and related factors.METHOD: this is a cross-sectional study involving 84 Brazilian and 128 Italian undergraduate. For the evaluation of se... | ['Adolescent', 'Adult', 'Brazil', 'Cross-Sectional Studies', 'Education, Nursing, Baccalaureate', 'Female', 'Humans', 'Italy', 'Prevalence', 'Sexual Behavior', 'Sexual Dysfunction, Physiological', 'Sexual Dysfunctions, Psychological', 'Statistics, Nonparametric', 'Students, Nursing', 'Surveys and Questionnaires', 'Univ... | 29,972,544 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I02.358.462.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Inhibitory role of the distal small intestine on the gastric secretory response to meals in man. | The role of the distal small intestine on postprandial gastric function was determined in 6 healthy volunteers by diverting chyme from the intestine at a site 100 cm distal to the ligament of Treitz and comparing the results with those observed in the same subjects when chyme was exposed to the entire gut. Diversion of... | ['Adult', 'Eating', 'Female', 'Gastric Acidity Determination', 'Gastric Emptying', 'Gastric Juice', 'Humans', 'Intestine, Small', 'Male', 'Middle Aged'] | 631,508 | [['M01.060.116'], ['G07.203.650.283', 'G10.261.330'], ['E01.370.225.124.300', 'E01.370.372.300', 'E05.200.124.300'], ['G10.261.360.400'], ['A12.200.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684'], ['M01.060.116.630']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A literature-based intervention for women prisoners: preliminary findings. | Purpose The purpose of this paper is to investigate whether Shared Reading (SR), a specific literature-based intervention, is transposable to a prison context and whether mental health benefits identified in other custodial and non-custodial settings were reported by women prisoners. Design/methodology/approach In all,... | ['Adolescent', 'Adult', 'Aged', 'England', 'Female', 'Focus Groups', 'Humans', 'Literature', 'Mental Disorders', 'Mental Health', 'Mental Health Services', 'Middle Aged', 'Prisoners', 'Prisons', 'Reading', "Women's Health", 'Young Adult'] | 27,921,635 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.542.363.300'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.517'], ['F03'], ['F02.418', 'N01.400.500'], ['F04.408', 'N02.421.461'], ['M01.060.116.630'], ['M01.729'], ['I01.880.604.7... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Informati... | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
[Internal fixation for fractures of the lateral malleolus with titanium "crown"-plates (author's transl)]. | This team of authors constructed a so called "crown"-plate from titanium, suitable for fixation of lateral malleolar fractures. The plate seems to be ideal for Weber-B type fractures, which are level with the joint space, and it can be applied in the more distal (Weber-A) and proximal (Weber-C) fractures too. The titan... | ['Ankle Injuries', 'Ankle Joint', 'Bone Plates', 'Fracture Fixation, Internal', 'Fractures, Bone', 'Humans', 'Radiography', 'Titanium'] | 6,114,227 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Sexual activity, contraception and unwanted pregnancy at puberty and adolescence]. | The sexual activity during the pubertal-adolescent age and the closely connected with it questions about psychological consequences, extramarital conceptions, deliveries and abortions is a problem with more and more increasing significance in the world. The present study includes an inquiry on 468 girls and boys at the... | ['Adolescent', 'Bulgaria', 'Contraception Behavior', 'Female', 'Humans', 'Motivation', 'Pregnancy', 'Pregnancy in Adolescence', 'Pregnancy, Unwanted', 'Puberty', 'Sexual Behavior', 'Surveys and Questionnaires', 'Urban Population'] | 2,091,474 | [['M01.060.057'], ['Z01.542.248.180'], ['F01.145.688.500', 'G08.686.784.891.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['G08.686.784.769'], ['G08.686.784.769.494'], ['G08.686.784.769.580'], ['G08.686.760', 'G08.686.841.374'], ['F01.145.802'], ['E05.318.308.980', 'N05.715... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Clinical pharmacokinetics of nifedipine gastrointestinal therapeutic system. A controlled-release formulation of nifedipine. | The pharmacokinetics of nifedipine following intravenous administration can be represented by an open two-compartment model with a terminal elimination half-life of about two hours. Nifedipine is extensively biotransformed to inactive metabolites, and the total body clearance (450 to 700 ml/minute) is primarily due to ... | ['Biological Availability', 'Delayed-Action Preparations', 'Humans', 'Intestinal Absorption', 'Nifedipine', 'Osmosis', 'Tablets'] | 3,503,594 | [['G03.787.151', 'G07.690.725.129'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['D03.383.725.203.540'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Population pharmacokinetics and initial dosing regimen optimization of cyclosporin in pediatric hemophagocytic lymphohistiocytosis patients. | Hemophagocytic lymphohistiocytosis (HLH) is induced by various triggers, including genetic factors, infections, autoimmune diseases, lymphoma or other malignancies. Cyclosporin is one of the clinical treatments for HLH. However, cyclosporin has considerable inter- and intra-individual variabilities in pharmacokinetics ... | ['Adolescent', 'Child', 'Child, Preschool', 'Cyclosporine', 'Female', 'Humans', 'Immunosuppressive Agents', 'Lymphohistiocytosis, Hemophagocytic', 'Male'] | 31,382,792 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['C15.604.250.410.575']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibitory Smads and bone morphogenetic protein (BMP) modulate anterior photoreceptor cell number during planarian eye regeneration. | Planarians represent an excellent model to study the processes of body axis and organ re-specification during regeneration. Previous studies have revealed a conserved role for the bone morphogenetic protein (BMP) pathway and its intracellular mediators Smad1/5/8 and Smad4 in planarian dorsoventral (DV) axis re-establis... | ['Animals', 'Bone Morphogenetic Proteins', 'Eye', 'In Situ Hybridization', 'Nerve Regeneration', 'Neurons', 'Photoreceptor Cells', 'Planarians', 'Regeneration', 'Signal Transduction', 'Smad Proteins, Inhibitory', 'X-Rays'] | 22,451,003 | [['B01.050'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['A01.456.505.420', 'A09.371'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['G11.561.585', 'G16.762.611'], ['A08.675', 'A11.671'], ['A08.675.650.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
BCMA becomes first Canadian medical group to form Committee on Violence. | The British Columbia Medical Association has established a Committee on Violence to look at the impact violence has on society and help find ways to educate physicians about how to identify, counsel and prevent violent behaviour. The issue is becoming more pressing as downsizing closes mental-health facilities, putting... | ['Attitude of Health Personnel', 'British Columbia', 'Female', 'Health Education', 'Humans', 'Male', 'Occupational Diseases', "Physician's Role", 'Physicians', 'Rape', 'Societies, Medical', 'Violence', 'Wounds and Injuries'] | 8,943,939 | [['F01.100.050', 'N05.300.100'], ['Z01.107.567.176.160'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C24'], ['F01.829.316.616.625.600'], ['M01.526.485.810', 'N02.360.810'], ['I01.198.240.748.640', 'I01.198.240.856.744', 'I01.880.735.900.772'], ['N03.540.828.589'], ['I01.198.2... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Accurate segmentation of respiration waveforms from infants enabling identification and classification of irregular breathing patterns. | Although the precise causes of Sudden Infant Death Syndrome (SIDS) are still unclear there is evidence to suggest that hypoxaemia may be a contributory factor. Transcutaneous oxygen monitors can be used but are unsatisfactory for young babies in the home. As an alternative approach, respiratory patterns can be studied ... | ['Algorithms', 'Classification', 'Decision Support Techniques', 'Humans', 'Infant', 'Monitoring, Physiologic', 'Respiration', 'Sudden Infant Death'] | 8,162,260 | [['G17.035', 'L01.224.050'], ['L01.100', 'L01.453.245.275'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.520'], ['G09.772.705'], ['C23.550.260.322.625', 'C23.550.260.657.500']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
The toxicology data bank. | The paper describes the Toxicology Data Bank, a new system under development that will provide on-line access to chemical, physical, toxicologic, pharmacologic, use, and manufacturing data on 4000-5000 selected chemicals including drugs. | ['Abstracting and Indexing', 'Computers', 'Data Display', 'Information Systems', 'National Library of Medicine (U.S.)', 'Online Systems', 'Subject Headings', 'Toxicology', 'United States'] | 1,249,135 | [['L01.453.245.100'], ['L01.224.230.260'], ['F02.784.412.221', 'L01.296'], ['L01.313.500.750.300'], ['I01.409.418.750.600.650.496.490', 'J03.400.596.831.937.725', 'L01.346.596.719.875.500', 'N03.540.052.750.490', 'N03.540.348.500.500.600.650.496.742'], ['L01.313.500.750.300.742'], ['L01.453.245.945.700'], ['H01.158.891... | ['Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Structural model of vestibular effects on the blood pressure. | The model described in the present work is a structural presentation of certain aspcets of the vesibular effects on the blood pressure. The model comprises the joint action of the otolith system and the semicircular canals, gangl. Scarpe, the vestibular nuclei, the vasomotor centre and the nuclei of n. vagus. The direc... | ['Blood Pressure', 'Models, Structural', 'Synaptic Transmission', 'Vagus Nerve', 'Vasomotor System', 'Vestibule, Labyrinth'] | 189,571 | [['E01.370.600.875.249', 'G09.330.380.076'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['G02.111.820.850', 'G04.835.850', 'G07.265.880', 'G11.561.830'], ['A08.800.050.050.925', 'A08.800.050.600.825', 'A08.800.800.060.920', 'A08.800.800.120.900'], ['A08.800.050.800.900'], ['A09.246.300.909']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
What makes a difference in exercise-induced bronchoconstriction: an 8 year retrospective analysis. | BACKGROUND: Exercise-induced bronchoconstriction (EIB) was recently classified into EIB alone and EIB with asthma, based on the presence of concurrent asthma.OBJECTIVE: Differences between EIB alone and EIB with asthma have not been fully described.METHODS: We retrospectively reviewed who visited an allergy clinic for ... | ['Adult', 'Asthma', 'Bronchial Hyperreactivity', 'Bronchoconstriction', 'Bronchoconstrictor Agents', 'Exercise', 'Exercise Test', 'Female', 'Humans', 'Humidity', 'Male', 'Methacholine Chloride', 'Retrospective Studies', 'Temperature', 'Young Adult'] | 24,498,034 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C08.127.210'], ['G09.772.705.700.080'], ['D27.505.696.663.050.100', 'D27.505.954.796.170'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Peritoneal exudate in larval Rana pipiens contains cells that are embryologically derived from dorsal lateral plate mesoderm. | The embryonic origin of cells functioning in a peritoneal exudate response of larval Rana pipiens was investigated. Normal larva received injections of sodium caseinate on day 0 and cells in the peritoneal cavity were assayed on days 3, 5, 7, 9, 11, 13 and 16. Experimental animals that received cytogenetically labeled ... | ['Animals', 'Ascitic Fluid', 'Caseins', 'Cell Differentiation', 'Exudates and Transudates', 'Hematopoietic Stem Cells', 'Larva', 'Mesoderm', 'Phagocytes', 'Rana pipiens'] | 6,603,374 | [['B01.050'], ['A12.207.119'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['G04.152'], ['A12.383'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A16.504.660'], ['A11.733', 'A15.382.680'], ['B01.050.150.900.090.180.708.310']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endotoxin exposure, wheezing, and rash in infancy in a New Zealand birth cohort. | BACKGROUND: Wheezing in infancy is common and is associated with small lungs, viral respiratory tract infection, and environmental tobacco smoke exposure. Recently, increased levels of endotoxin in the domestic environment have also been associated with infant wheezing, particularly among infants with a family history ... | ['Cohort Studies', 'Dust', 'Endotoxins', 'Environmental Exposure', 'Exanthema', 'Humans', 'Hypersensitivity, Immediate', 'Infant', 'New Zealand', 'Prevalence', 'Prospective Studies', 'Respiratory Sounds', 'Risk Factors', 'Surveys and Questionnaires'] | 17,157,655 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D20.633.222'], ['D23.946.123.329'], ['N06.850.460.350'], ['C17.800.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480'], ['M01.060.703'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E05.318.308.985.525.750', 'N01.224.935.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adiposity in Czech children followed from 1 month of age to adulthood: analysis of individual BMI patterns. | In Czechoslovakia, overweight and nutrition-associated pathologies are frequent. The body mass index (BMI) is often used in the clinical assessment of adiposity in children and adults. Its variations during growth are well documented. A cohort of 300 newborns were selected at random in Prague between 1956 and 1960. Wei... | ['Adolescent', 'Adult', 'Body Mass Index', 'Child', 'Child, Preschool', 'Czechoslovakia', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Longitudinal Studies', 'Male', 'Obesity'] | 8,257,077 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.586.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Basedow's disease in a female patient with breast cancer metastasizing to the thyroid]. | A case is presented of a woman with a breast cancer who developed Basedow's disease several months after the diagnosis of the cancer. In spite of the antithyrotoxic treatment the Basedow's symptoms persisted till the end of life. The case is compared with other similar cases in which the combination of Basedow's diseas... | ['Breast Neoplasms', 'Carcinoma', 'Female', 'Graves Disease', 'Humans', 'Lymphatic Metastasis', 'Middle Aged', 'Thyroid Gland', 'Thyroid Neoplasms'] | 3,433,725 | [['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['A06.300.900'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C1... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The endodermal origin of the endocrine cells of an adenocarcinoma of the colon of the rat. | A transplantable adenocarcinoma of the colon of the rat, which contained mucous, columnar, endocrine, and undifferentiated carcinoma cells, were cloned to see if each of the differentiated cell lineages had a common cell or origin. Four clonal lines were produced by the transplantation of single cells using micropipett... | ['Adenocarcinoma', 'Animals', 'Clone Cells', 'Colonic Neoplasms', 'Endoderm', 'Enterochromaffin Cells', 'Male', 'Neoplasm Transplantation', 'Neoplasms, Experimental', 'Rats', 'Rats, Inbred F344'] | 7,116,287 | [['C04.557.470.200.025'], ['B01.050'], ['A11.251.353'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['A16.504.407'], ['A03.556.875.875.440.250', 'A06.224.358', 'A06.390.021', 'A10.615.550.291.162', 'A11.382.625.031', 'A11.4... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early smoking in school-aged children with and without a diagnosis of asthma. | BACKGROUND: Research has shown that adolescents with asthma are as likely as and sometimes even more likely to smoke than their peers without asthma. The current study examined whether the prevalence of the first active smoking experience differs for children (9-12 years of age) diagnosed with asthma compared with chil... | ['Age Factors', 'Asthma', 'Child', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Mother-Child Relations', 'Netherlands', 'Sex Factors', 'Smoking', 'Socioeconomic Factors'] | 21,746,750 | [['N05.715.350.075', 'N06.850.490.250'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F01.829.263.370.290.170'], ['Z01.542.651'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.805'], ['I01.880.853.996', 'N01.82... | ['Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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