Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Financial triage in transfer of trauma patients: a myth or a reality? | BACKGROUND: It has been alleged that smaller hospitals transfer out uninsured trauma patients (wallet biopsy), putting the financial burden on major trauma centers.METHODS: We undertook a retrospective analysis of the National Trauma Data Bank to compare patients who received care at major trauma centers after being tr... | ['Female', 'Humans', 'Injury Severity Score', 'Insurance Coverage', 'Male', 'Medically Uninsured', 'Multiple Trauma', 'Patient Transfer', 'Retrospective Studies', 'Trauma Centers', 'Triage'] | 19,427,626 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N05.715.360.300.715.500.800.400'], ['N03.219.521.576.265'], ['M01.385'], ['C26.640'], ['E02.760.169.624', 'E02.760.400.630', 'N02.421.585.169.624', 'N02.421.585.400.630', 'N04.590.233.727.210.624... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Generation of reactive oxygen species mediates butein-induced apoptosis in neuroblastoma cells. | Flavonoids exhibit chemopreventive and chemotherapeutic effects. Butein, a bioactive flavonoid isolated from numerous native plants, has been shown to induce apoptosis in human cancer cells. In the current study, the molecular mechanisms of butein action on cell proliferation and apoptosis of neuroblastoma cells were e... | ['Animals', 'Antineoplastic Agents, Phytogenic', 'Antioxidants', 'Apoptosis', 'Caspase 3', 'Cell Line, Tumor', 'Cell Survival', 'Chalcones', 'Dose-Response Relationship, Drug', 'G1 Phase Cell Cycle Checkpoints', 'Mice', 'Neuroblastoma', 'Oxidative Stress', 'Poly(ADP-ribose) Polymerases', 'Proto-Oncogene Proteins', 'Pro... | 22,245,810 | [['B01.050'], ['D27.505.954.248.179'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assembly of a nanoreactor system with confined magnetite core and shell for enhanced Fenton-like catalysis. | Conventional solid catalysts for heterogeneous Fenton-like reactions in bulk solution usually suffer from aggregation and vulnerability, which greatly lower the catalytic efficiency and hamper their practical application. Herein, we demonstrate a promising yolk-shell nanostructure with both the core and the shell compo... | ['Catalysis', 'Chlorophenols', 'Ferric Compounds', 'Ferrosoferric Oxide', 'Nanostructures'] | 24,737,528 | [['G02.130'], ['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['D01.490.100'], ['D01.490.100.375', 'D01.490.200.350', 'D01.578.285'], ['J01.637.512']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Inhibitory effects of ascorbic acid and folinic acid on chromosome aberrations induced by pyrimethamine in vitro. | In this study, the anticlastogenic effects of ascorbic acid and the protective effect of folinic acid against the formation of chromosomal aberrations in humans by pyrimethamine were investigated. Pyrimethamine is a folic acid antagonist used for the treatment of malaria and toxoplasmosis. In this study, 18 different h... | ['Ascorbic Acid', 'Cells, Cultured', 'Chromosome Aberrations', 'Dose-Response Relationship, Drug', 'Folic Acid Antagonists', 'Humans', 'Leucovorin', 'Mitosis', 'Pyrimethamine'] | 12,210,498 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['A11.251'], ['C23.550.210', 'G05.365.590.175'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.733.631.400.800.350.450', 'D08.211.840.300.500'], ['G04.144.220.220.781', 'G05.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histological analysis of the Ankylos peri-implant soft tissues in a dog model. | PURPOSE: The importance of the soft tissue-implant interface is enhanced by the presence of a microgap between the implant and the abutment, which represents a contamination site for bacteria. The aim of this study was to investigate the interface between the Ankylos gap-free implant system and the surrounding soft tis... | ['Alveolar Process', 'Animals', 'Collagen', 'Connective Tissue', 'Dental Abutments', 'Dental Implants', 'Dental Prosthesis Design', 'Dogs', 'Epithelial Attachment', 'Epithelial Cells', 'Extracellular Matrix', 'Female', 'Microscopy, Electron, Scanning', 'Models, Animal', 'Periodontitis', 'Periodontium', 'Surface Propert... | 14,560,487 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['B01.050'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A10.165'], ['E06.780.346.500', 'E07.695.190.175'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.625', 'E06.912.145'], ['B01.050.150.900.649.313.75... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Zefinha - the name of abandonment. | Zefinha has been living in a forensic hospital for the last 39 years. She is the longest female inhabitant surviving under compulsory psychiatric treatment in Brazil. This paper discusses how the ethical rule of anonymity might be revised in research concerning a unique case involving severe violations of human rights.... | ['Adult', 'Brazil', 'Commitment of Mentally Ill', 'Disclosure', 'Female', 'Human Experimentation', 'Human Rights', 'Humans', 'Morals', 'Research'] | 26,331,499 | [['M01.060.116'], ['Z01.107.757.176'], ['F04.096.544.335.200', 'N03.706.535.351.200'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['E05.445', 'H01.770.644.145.365'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.500', 'K01.752.566'], ['H01.770.644']] | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Humanities... | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Addressing Eeuropean environmental legislation. | Medical device companies need to meet European requirements designed to protect the environment.The deadlines for some of the requirements have already passed. This article discusses a European Regulation and two Directives, and a means for meeting environmental requirements in an effective manner. | ['Conservation of Natural Resources', 'Equipment and Supplies', 'European Union', 'Hazardous Substances', 'Industry'] | 19,370,911 | [['J01.256', 'N06.230.080'], ['E07'], ['I01.615.500.475'], ['D27.888.426'], ['J01.576']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Protein kinase B alpha/Akt1 regulates placental development and fetal growth. | Protein kinase B alpha (PKB alpha/Akt1) is implicated in the regulation of metabolism, transcription, cell survival, angiogenesis, cell migration, growth, and tumorigenesis. Previously, it was reported that PKB alpha-deficient mice are small with increased neonatal mortality (Cho, H., Thorvaldsen, J. L., Chu, Q., Feng,... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Western', 'DNA Primers', 'Embryonic and Fetal Development', 'Immunohistochemistry', 'Mice', 'Mice, Knockout', 'Molecular Sequence Data', 'Placentation', 'Protein-Serine-Threonine Kinases', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-akt'] | 12,783,884 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G07.345.500.325', 'G08.686.784.170'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Neural dynamics of perceptual order and context effects for variable-rate speech syllables. | How does the brain extract invariant properties of variable-rate speech? A neural model, called PHONET, is developed to explain aspects of this process and, along the way, data about perceptual context effects. For example, in consonant-vowel (CV) syllables, such as /ba/ and /wa/, an increase in the duration of the vow... | ['Attention', 'Auditory Pathways', 'Brain', 'Brain Mapping', 'Humans', 'Mental Recall', 'Neural Networks, Computer', 'Phonetics', 'Psycholinguistics', 'Speech Acoustics', 'Speech Perception'] | 10,598,464 | [['F02.830.104.214'], ['A08.612.220.110'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['G17.485', 'L01.224.050.375.605'], ['L01.559.598.518'], ['F02.694', 'F04.096.586', 'L01.559.598.628'], ['G11.5... | ['Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems. | In the present paper, we report the effect of a grape seed procyanidin extract (GSPE) on antioxidant enzyme systems (AOEs). Gene expression was tested using the hepatocarcinoma cell line HepG2 by exposing it to several GSPE doses between 0 and 100 mg/L for 24 h. We evaluated mRNA expression and enzyme activity levels u... | ['Cell Line, Tumor', 'Gene Expression Regulation, Enzymologic', 'Glutathione Peroxidase', 'Glutathione Reductase', 'Glutathione Transferase', 'Hepatoblastoma', 'Humans', 'Liver Neoplasms', 'Oxidative Stress', 'Proanthocyanidins', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Seeds', 'Superoxide ... | 16,028,999 | [['A11.251.210.190', 'A11.251.860.180'], ['G05.308.320'], ['D08.811.682.732.500'], ['D08.811.682.667.092'], ['D08.811.913.225.500'], ['C04.557.435.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['G03.673', 'G07.775.750'], ['D03.383.663.283.266.450.700', 'D03.6... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Does austerity really kill? | A growing body of the literature has argued that austerity has been bad for health, though without directly measuring austerity. This paper explicitly distinguishes the association of mortality with macroeconomic fluctuations from that with fiscal policy measures, using data for 28 European Union (EU) countries coverin... | ['Accidents, Traffic', 'Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Economics', 'Europe', 'Female', 'Humans', 'Infant', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Mortality', 'Policy', 'Suicide', 'Young Adult'] | 31,003,198 | [['N06.850.135.392'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['I01.261', 'N03.219'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.55... | ['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Green synthesis of silver nanoparticles using Terminalia chebula extract at room temperature and their antimicrobial studies. | A green rapid biogenic synthesis of silver nanoparticles (Ag NPs) using Terminalia chebula (T. chebula) aqueous extract was demonstrated in this present study. The formation of silver nanoparticles was confirmed by Surface Plasmon Resonance (SPR) at 452 nm using UV-visible spectrophotometer. The reduction of silver ion... | ['Anti-Bacterial Agents', 'Bacterial Infections', 'Gallic Acid', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Green Chemistry Technology', 'Humans', 'Hydrolyzable Tannins', 'Metal Nanoparticles', 'Oxidation-Reduction', 'Plant Extracts', 'Polyphenols', 'Silver', 'Terminalia', 'X-Ray Diffraction'] | 22,381,795 | [['D27.505.954.122.085'], ['C01.150.252'], ['D02.241.223.100.300.200', 'D02.241.511.390.200', 'D02.455.426.559.389.127.281.200', 'D02.455.426.559.389.657.410.200'], ['B03.440'], ['B03.510'], ['J01.897.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.300.200.299', 'D02.241.511.390.200.299', 'D02... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Daily diary and ambulatory activity monitoring of sleep in patients with insomnia associated with chronic musculoskeletal pain. | Insomnia is a significant problem for many people with chronic pain. In this study, we used a combination of daily sleep diaries and ambulatory activity monitoring (actigraphy) to: (i) examine the nature and severity of the sleep disturbance in this patient group; (ii) determine the concordance between sleep diary and ... | ['Activity Cycles', 'Adult', 'Chronic Disease', 'Female', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Musculoskeletal Diseases', 'Pain', 'Sleep', 'Sleep Initiation and Maintenance Disorders'] | 9,539,676 | [['G07.180.562.797.500'], ['M01.060.116'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060.116.630'], ['E01.370.520'], ['C05'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['F02.830.855',... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
New strategy for comprehensive analysis of gene functions in embryonic stem cells. | At present, the limitation of Phenotype-based genetic screening in embryonic stem cells (ESCs) is the diploid nature of the genome. Since it is known that cells deficient in the Bloom's syndrome gene (Blm) show an increased rate of homologous recombination, we have developed a new system to conditionally regulate the B... | ['Alleles', 'Animals', 'Chromosomes', 'Embryo, Mammalian', 'Embryo, Nonmammalian', 'Gene Expression Regulation', 'Mutation', 'Stem Cells'] | 16,903,413 | [['G05.360.340.024.340.030'], ['B01.050'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['A16.254'], ['A13.350', 'A16.331'], ['G05.308'], ['G05.365.590'], ['A11.872']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Paradoxical forearm vasodilatation and haemodynamic improvement during cardiopulmonary baroreceptor unloading in patients with congestive heart failure. | 1. To examine the contribution of paradoxical reflex forearm vasodilatation during unloading of cardiopulmonary baroreceptors to systemic haemodynamics, the responses of central and peripheral haemodynamics during lower-body negative pressure were measured in 24 patients with chronic congestive heart failure (New York ... | ['Adult', 'Aged', 'Cardiac Output', 'Echocardiography', 'Forearm', 'Heart Failure', 'Hemodynamics', 'Humans', 'Lower Body Negative Pressure', 'Male', 'Middle Aged', 'Norepinephrine', 'Pressoreceptors', 'Vascular Resistance', 'Vasodilation'] | 8,384,949 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A01.378.800.585'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.278.500'], ['M01.060.116.630'], ['D02.033.100.291.502', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Correlating Genotype and Phenotype in the Asexual Yeast Candida orthopsilosis | Candida orthopsilosis is diploid asexual yeast that causes human disease. Most C. orthopsilosis isolates arose from at least four separate hybridizations between related, but not identical, parents. Here, we used population genomics data to correlate genotypic and phenotypic variation in 28 C. orthopsilosis isolates. W... | ['Animals', 'Antifungal Agents', 'CRISPR-Cas Systems', 'Caffeine', 'Candida parapsilosis', 'Codon, Terminator', 'Fungal Proteins', 'Genotype', 'Ketoconazole', 'Lepidoptera', 'Microbial Sensitivity Tests', 'Microorganisms, Genetically-Modified', 'Nystatin', 'Phenotype', 'Polymorphism, Single Nucleotide', 'Virulence'] | 31,352,406 | [['B01.050'], ['D27.505.954.122.136'], ['G05.308.203.374.394'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['B01.300.107.795.095.600', 'B01.300.381.147.600', 'B01.300.930.176.600'], ['D13.444.735.544.355.250', 'G05.360.335.355.250', 'G05.360.340.024.340.137.190.250'], ['D12.776.354'], ['G05.380'], ['D03.383.60... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reverse-Flow Intrinsic Fasciocutaneous Island Flaps in Foot Reconstruction. | Reconstruction of soft tissue defects in the foot remains a challenge due to its specialized tissue for weightbearing and ambulation. Considering the principle of replacing "like with like," adjacent soft tissues would be a best option for a donor site. Although several kinds of reverse-flow island flaps for the lower ... | ['Adult', 'Female', 'Humans', 'Leg Injuries', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Skin Transplantation', 'Soft Tissue Injuries', 'Surgical Flaps', 'Trauma Severity Indices', 'Wound Closure Techniques'] | 29,132,254 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['M01.060.116.630'], ['N04.761.559', 'N05.715.360.575'], ['E04.680'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.7... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Psychological stress has no association with salivary levels of â-defensin 2 and â-defensin 3. | BACKGROUND: Recent studies suggest that stress can predispose an individual to the development of periodontal disease, but the exact biological mechanism is unknown. Considering that psychological stress can down-regulate the production of â-defensins (antimicrobial peptides produced in the oral cavity), the aim of the... | ['Adaptation, Physiological', 'Adolescent', 'Adult', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Reference Values', 'Saliva', 'Salivary Proteins and Peptides', 'Stress, Psychological', 'Young Adult', 'beta-Defensins'] | 20,819,126 | [['G07.025', 'G16.012.500'], ['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.978.810'], ['A12.200.666'], ['D12.644.848', 'D12.776.850'], ['F01.145.126.990', 'F02.830.900'], ['M01.060.116.815'], ['D12.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subtalar kinematics following resection of tarsal coalition. | BACKGROUND: Pain relief and functional improvement in the short term have been demonstrated in the majority of patients with tarsal coalition following resection. Recreation of normal subtalar kinematics is an important goal in these patients as well, and may have long term implications. The purpose of our study was to... | ['Adolescent', 'Biomechanical Phenomena', 'Case-Control Studies', 'Child', 'Female', 'Foot Deformities', 'Humans', 'Male', 'Pronation', 'Range of Motion, Articular', 'Subtalar Joint', 'Supination', 'Tarsal Bones', 'Walking', 'Young Adult'] | 19,026,201 | [['M01.060.057'], ['G01.154.090', 'G01.374.089'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['C05.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.410.698.840'], ['E01.370.600.700', 'G11.427.760'], ['A02.835.583.378.831.780'], ['G11.427.410.698.920'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Ligand binding to a G protein-coupled receptor captured in a mass spectrometer. | G protein (heterotrimeric guanine nucleotide-binding protein)-coupled receptors belong to the largest family of membrane-embedded cell surface proteins and are involved in a diverse array of physiological processes. Despite progress in the mass spectrometry of membrane protein complexes, G protein-coupled receptors hav... | ['Adenosine Diphosphate', 'Ligands', 'Mass Spectrometry', 'Models, Molecular', 'Molecular Conformation', 'Phosphorylation', 'Protein Binding', 'Receptors, G-Protein-Coupled', 'Receptors, Purinergic P2Y1', 'Structure-Activity Relationship'] | 28,630,934 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D27.720.470.480'], ['E05.196.566'], ['E05.599.595'], ['G02.111.570.820'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['G02.111.679', 'G03.808'], ['D12.776.543.750.695'], ['D12.776.543.750.695.700.720.500.100', 'D12.776.543.750.720.700.720... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurovascular compression syndrome of the brain stem with opsoclonus-myoclonus syndrome combined with vestibular paroxysmia and autonomic symptoms. | We describe a rare case of neurovascular compression syndrome (NVCS) of the brain stem and opsoclonus-myoclonus syndrome (OMS) complicated with vestibular paroxysmia (VP) and autonomic symptoms. Moreover, we discuss the case with respect to the available information in medical literature. A 36-year-old man with vertigo... | ['Adult', 'Anticonvulsants', 'Autonomic Nervous System Diseases', 'Brain Stem', 'Drug Therapy, Combination', 'Humans', 'Opsoclonus-Myoclonus Syndrome', 'Treatment Outcome', 'Vertebral Artery', 'Vertigo'] | 31,534,075 | [['M01.060.116'], ['D27.505.954.427.080'], ['C10.177'], ['A08.186.211.132'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.550.600', 'C04.730.856.596', 'C10.228.758.500', 'C10.292.562.831', 'C10.574.781.662', 'C10.597.350.500.500', 'C11.590.725'], ['E01.789.800', 'N04.761.559.590.800',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preliminary evaluation of altered brain microstructure in the emotion-cognition region in children with haemophilia A: a diffusional kurtosis imaging study. | AIM: Using diffusional kurtosis imaging (DKI) to assess the impact of emotional disorders on microstructural changes of the brain in children with haemophilia A.MATERIALS AND METHODS: Diffusional kurtosis imaging was acquired from haemophilia A (n = 22) and controls (n = 22) using a 3T scanner. A regression analysis of... | ['Adolescent', 'Brain', 'Cognition', 'Emotions', 'Hemophilia A', 'Humans', 'Male'] | 28,205,277 | [['M01.060.057'], ['A08.186.211'], ['F02.463.188'], ['F01.470'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nanopolymeric micelle effect on the transdermal permeability, the bioavailability and gene expression of plasmid. | This study attempts to investigate the transdermal permeability, the bioavailability and gene expression of plasmid formulated with nonionic poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) polymeric micelles (PM). Dynamic light scattering (DLS) and atomic force microscopy (AFM) were used t... | ['Administration, Cutaneous', 'Animals', 'Biological Availability', 'Chemical Phenomena', 'Gene Expression', 'Gene Transfer Techniques', 'Half-Life', 'Male', 'Mice', 'Mice, Nude', 'Micelles', 'Nanostructures', 'Plasmids', 'Polyethylene Glycols', 'Propylene Glycols', 'Recombinant Proteins', 'Skin', 'Skin Absorption', 'S... | 22,142,416 | [['E02.319.267.120.060'], ['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['G02'], ['G05.297'], ['E05.393.350'], ['G01.910.405'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['D05.374', 'D26.255.560'], ['J01.637.512'], ['G05.360.600'], ['D02.033.455.250.700', 'D05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The correlation between breastfeeding self-efficacy and maternal postpartum depression in southern Brazil. | OBJECTIVE: To investigate the relationship between breastfeeding self-efficacy and postpartum depression symptoms in a sample of Portuguese-speaking mothers in southern Brazil.BACKGROUND: There remains equivocal evidence regarding a putative association between breastfeeding self-efficacy and postpartum depression.METH... | ['Adult', 'Brazil', 'Breast Feeding', 'Cross-Sectional Studies', 'Depression, Postpartum', 'Female', 'Humans', 'Interviews as Topic', 'Language', 'Prevalence', 'Self Efficacy', 'Surveys and Questionnaires', 'Young Adult'] | 23,427,927 | [['M01.060.116'], ['Z01.107.757.176'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C13.703.844.253', 'F03.600.300.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L0... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Extraconal solitary fibrous tumor of the orbit]. | Solitary fibrous tumors (SFT) are rare spindle cell neoplasms derived from specialized fibroblasts. This tumor was first described in the pleura and later in the whole body including the orbit. Although an SFT is generally a benign tumor malignant transformation and metastasization have also been observed in a few case... | ['Humans', 'Male', 'Middle Aged', 'Orbital Neoplasms', 'Solitary Fibrous Tumors', 'Treatment Outcome'] | 22,972,174 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.149.721.656', 'C04.588.364.659', 'C05.116.231.754.659', 'C11.319.457', 'C11.675.659'], ['C04.557.450.565.590.797'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of perioperative contralateral stroke after carotid endarterectomy. | OBJECTIVE: Contralateral stroke is an infrequent cause of perioperative stroke after carotid endarterectomy (CEA). Whereas the risks of ipsilateral stroke complicating CEA have been discriminated, factors that lead to contralateral stroke are poorly defined. The purpose of this study was to identify the risk of periope... | ['Aged', 'Aged, 80 and over', 'Carotid Stenosis', 'Chi-Square Distribution', 'Endarterectomy, Carotid', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'New England', 'Odds Ratio', 'Operative Time', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors... | 28,697,940 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.100.814.456.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Protein oxidation in emulsified cooked burger patties with added fruit extracts: Influence on colour and texture deterioration during chill storage. | The influence of protein oxidation, as measured by the dinitrophenylhydrazine (DNPH) method, on colour and texture changes during chill storage (2 degrees C, 12days) of cooked burger patties was studied. Extracts from arbutus-berries (Arbutus unedoL., AU), common hawthorns (Crataegus monogynaL., CM), dog roses (Rosa ca... | ['Animals', 'Cattle', 'Cold Temperature', 'Color', 'Emulsions', 'Food Preservation', 'Food Technology', 'Fruit', 'Hydrazines', 'Meat', 'Muscle Proteins', 'Oxidation-Reduction', 'Plant Extracts', 'Protein Carbonylation', 'Refrigeration', 'Rosa'] | 20,416,800 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.590.540.199'], ['D20.280.260', 'D26.255.165.260'], ['J01.576.423.850.700'], ['J01.576.423.850'], ['A18.024.500', 'G07.203.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Clinical diagnosis of childhood psychoses]. | I have tried to summarize the different points of view in regard to clinical diagnosis of child psychosis. The main purpose is to reach a more universal agreement to base a diagnosis that allows us not only to facilitate an early diagnosis but also its treatment and above all better bases for research. Infantile psycho... | ['Child', 'Humans', 'Psychological Tests', 'Psychotic Disorders', 'Schizophrenia, Childhood'] | 1,052,702 | [['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711'], ['F03.700.675'], ['F03.625.968']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Small bowel obstruction due to a right-sided paraduodenal hernia: a case report. | Small bowel obstruction (SBO) diagnosed with abdominal computed tomography (CT) has been extensively studied in radiology literature. We present a case report of SBO due to a rare right-sided paraduodenal hernia diagnosed preoperatively on a non-contrast CT and confirmed surgically. | ['Duodenal Diseases', 'Female', 'Hernia, Abdominal', 'Humans', 'Intestinal Obstruction', 'Intestine, Small', 'Middle Aged', 'Tomography, X-Ray Computed'] | 19,551,425 | [['C06.405.469.275'], ['C23.300.707.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['A03.556.124.684'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of flow pulsatility on arterial drug distribution in stent-based therapy. | Drug-eluting stents reside in a dynamic fluid environment where the extent to which drugs are distributed within the arterial wall is critically modulated by the blood flowing through the arterial lumen. Yet several factors associated with the pulsatile nature of blood flow and their impact on arterial drug deposition ... | ['Arteries', 'Drug-Eluting Stents', 'Models, Cardiovascular', 'Pharmaceutical Preparations', 'Pulsatile Flow'] | 23,541,929 | [['A07.015.114'], ['E07.695.750.500'], ['E05.599.395.161'], ['D26'], ['G01.482.620', 'G09.330.380.630.555']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Decoding of facial emotions, in terms of expressiveness, by schizophrenics and depressives. | In a comparison of reactions to expressed emotions, 48 schizophrenics, 40 depressives, and 50 nonpatient controls were asked to identify the extreme and the least extreme expressions of six emotions. Schizophrenics identified the extreme expressions of emotions significantly better than the least extreme ones, whilst d... | ['Adult', 'Depressive Disorder', 'Emotions', 'Facial Expression', 'Female', 'Humans', 'Judgment', 'Male', 'Psychological Tests', 'Schizophrenic Psychology'] | 3,423,162 | [['M01.060.116'], ['F03.600.300'], ['F01.470'], ['E01.370.600.225', 'F01.145.209.530.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['F04.711'], ['F04.824']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
When insurance is not enough: racial and ethnic disparities in immunizations for the Medicare population. | This review article discusses disparities in immunization rates for beneficiaries of the US Medicare program. The review considers: 1) historical and statistical information on rates of immunization; 2) goals set forward by the Centers for Medicaid and Medicare Services (CMS) to eliminate racial and ethnic health dispa... | ['African Americans', 'Aged', 'Centers for Medicare and Medicaid Services, U.S.', 'Ethnic Groups', 'European Continental Ancestry Group', 'Health Services Accessibility', 'Humans', 'Immunization', 'Influenza, Human', 'Medicare', 'Pneumonia, Pneumococcal', 'Quality Assurance, Health Care', 'Socioeconomic Factors', 'Unit... | 15,945,360 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['I01.409.418.750.600.310', 'N03.540.348.500.500.600.550'], ['M01.686.754', 'N01.224.317'], ['M01.686.508.400'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Birth weight, maternal weight and childhood leukaemia. | There is mounting evidence that childhood leukaemia is associated with high birth weight, but few studies have examined the relationship between leukaemia and other perinatal factors that influence birth weight, such as maternal weight or gestational weight gain. This case-cohort study included 916 acute lymphocytic le... | ['Adult', 'Birth Weight', 'Body Weight', 'Child', 'Ethnic Groups', 'Female', 'Gestational Age', 'Humans', 'Leukemia', 'Leukemia, Myeloid, Acute', 'Male', 'Maternal Age', 'Mothers', 'New York', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Pregnancy', 'Registries', 'Weight Gain'] | 16,736,025 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['M01.686.754', 'N01.224.317'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Nucleotide sequence of pnl gene from Erwinia carotovora Er. | The nucleotide sequence of pnl gene encoding pectin lyase (PNL; EC4.2.2.10)from Erwinia carotovora Er was determined. The structural gene of pnl consisted of 942 base pairs. An open reading frame that could encode a 33,700 dalton polypeptide consisting 314 amino acids was assigned. The molecular size of the polypeptide... | ['Amino Acid Sequence', 'Base Sequence', 'Binding Sites', 'Cloning, Molecular', 'Erwinia', 'Escherichia coli', 'Genes, Bacterial', 'Molecular Sequence Data', 'Open Reading Frames', 'Plasmids', 'Polysaccharide-Lyases', 'Restriction Mapping', 'Ribosomes', 'Sequence Homology, Nucleic Acid'] | 2,018,526 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.393.220'], ['B03.440.450.425.300', 'B03.660.250.150.175'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.35... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fat necrosis of the newborn--report on two cases. | Subcutaneous fat necrosis of the newborn is an uncommon disorder occurring during the prenatal stage. Generally occurring in full-term neonates or during the first four weeks after a traumatic delivery, the disorder is characterized by the appearance of hard subcutaneous nodules or plaques on the trunk, buttocks or thi... | ['Fat Necrosis', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Subcutaneous Fat'] | 22,068,788 | [['C23.550.717.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A10.165.114.830.750']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Production of a T-antigen-related protein in mammalian cells after stable transformation with a cloned SV40 gene fragment. | A recombinant plasmid based on pBR322 has been constructed which carries the replicator proximal early region of SV40 DNA, including the viral origin of replication (ORI). It lacks a major part of the tumour antigen 3'-coding region, the large T-antigen termination codon and the polyadenylation site. The recombinant pl... | ['Animals', 'Antigens, Viral', 'Antigens, Viral, Tumor', 'Cell Transformation, Viral', 'Cloning, Molecular', 'DNA, Recombinant', 'DNA, Viral', 'Genes, Viral', 'L Cells', 'Mice', 'Plasmids', 'Simian virus 40', 'Simplexvirus', 'Thymidine Kinase'] | 6,281,154 | [['B01.050'], ['D23.050.327'], ['D23.050.285.062', 'D23.050.327.062'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['E05.393.220'], ['D13.444.308.460'], ['D13.444.308.568'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['A11.251.210.505', 'A11.329.228.505... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The nuclear export receptor XPO-1 supports primary miRNA processing in C. elegans and Drosophila. | MicroRNA (miRNA) biogenesis proceeds from a primary transcript (pri-miRNA) through the pre-miRNA into the mature miRNA. Here, we identify a role of the Caenorhabditis elegans nuclear export receptor XPO-1 and the cap-binding proteins CBP-20/NCBP-2 and CBP-80/NCBP-1 in this process. The RNA-mediated interference of any ... | ['Active Transport, Cell Nucleus', 'Animals', 'Caenorhabditis elegans', 'Drosophila', 'Karyopherins', 'MicroRNAs', 'Nuclear Cap-Binding Protein Complex', 'Phenotype', 'RNA Cap-Binding Proteins', 'RNA Interference', 'Receptors, Cytoplasmic and Nuclear'] | 20,436,454 | [['G03.143.310.100', 'G03.143.700.100'], ['B01.050'], ['B01.050.500.500.294.400.875.660.250.250'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.157.530.750.500', 'D12.776.543.585.750.500', 'D12.776.660.502'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['D12.776.157.725.750.750'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrastructural organization and regulation of a biomaterial adhesin of Staphylococcus epidermidis. | Coagulase-negative staphylococci have emerged as important pathogens in infections associated with intravascular devices. Microbial adherence to biomaterial surfaces is a crucial step in the pathogenesis of these infections. Staphylococcal surface proteins (herein referred to as SSP-1 and SSP-2) are involved in the att... | ['Adhesins, Bacterial', 'Bacterial Adhesion', 'Biocompatible Materials', 'Catheterization', 'Down-Regulation', 'Fimbriae, Bacterial', 'Humans', 'Microspheres', 'Molecular Weight', 'Polystyrenes', 'Serum Albumin, Bovine', 'Staphylococcus epidermidis', 'Trypsin'] | 8,550,477 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['G06.099.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E02.148', 'E05.157'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A11.284.180.285', 'A20.843'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.565'], ['G02.494'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Extraction of a ruptured PTCA balloon catheter]. | While attempting angioplasty of a very tight and long circumflex lesion with a metal-shafted monorail catheter, the flexible part of the balloon catheter shaft broke off within the guiding catheter. The lost piece of catheter was then retrieved from the coronary artery by using an on-the-wire balloon catheter that was ... | ['Angioplasty, Balloon, Coronary', 'Coronary Disease', 'Coronary Vessels', 'Equipment Design', 'Equipment Failure', 'Female', 'Foreign Bodies', 'Humans', 'Middle Aged'] | 8,291,295 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['C14.280.647.250', 'C14.907.585.250'], ['A07.015.114.269', 'A07.015.908.194'], ['E05.320'], ['E05.325'], ['C26.392']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of diurnal temperature variation on microbial community and petroleum hydrocarbon biodegradation in contaminated soils from a sub-Arctic site. | Contaminated soils are subject to diurnal and seasonal temperature variations during on-site ex-situ bioremediation processes. We assessed how diurnal temperature variations similar to that in summer at the site from which petroleum hydrocarbon-contaminated soil was collected affect the soil microbial community and the... | ['Actinobacteria', 'Antarctic Regions', 'Arctic Regions', 'Base Sequence', 'Biodegradation, Environmental', 'Cold Temperature', 'DNA, Bacterial', 'Gammaproteobacteria', 'Hydrocarbons', 'Microbial Consortia', 'Mixed Function Oxygenases', 'Petroleum', 'RNA, Ribosomal, 16S', 'Seasons', 'Sequence Analysis, DNA', 'Soil', 'S... | 25,808,640 | [['B03.510.024', 'B03.510.460.400.400.049'], ['Z01.158'], ['Z01.208'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D13... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade. | Immune checkpoint blockade therapies have shown clinical promise in a variety of cancers, but how tumor-infiltrating T cells are activated remains unclear. In this study, we explore the functions of PD-L1 on dendritic cells (DCs), which highly express PD-L1. We observe that PD-L1 on DC plays a critical role in limiting... | ['Animals', 'Antigens, Neoplasm', 'B7-H1 Antigen', 'Cell Line, Tumor', 'Dendritic Cells', 'Disease Models, Animal', 'Female', 'HEK293 Cells', 'Humans', 'Interferon-gamma', 'Lymphocyte Activation', 'Lymphocytes, Tumor-Infiltrating', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'T-Lymphocytes, Cytotoxic', 'Tum... | 32,973,173 | [['B01.050'], ['D23.050.285'], ['D12.776.465.625', 'D12.776.467.150.300', 'D12.776.543.095.300', 'D23.050.301.285.400', 'D23.529.168.300'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.251.210.172.750',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of lymphocytes infiltrating the thyroid gland of Obese strain chickens. | Lymphocytes were isolated from the infiltrated thyroid glands of 2- to 5-wk-old Obese strain (OS) chickens with spontaneous autoimmune thyroiditis (SAT). Immunofluorescence analysis performed by using a panel of monoclonal and polyclonal antibodies revealed that 60% of thyroid infiltrating leukocytes (TIL) were mature ... | ['Animals', 'Autoimmune Diseases', 'Cell Movement', 'Chickens', 'Cyclophosphamide', 'Fluorescent Antibody Technique', 'Immunization, Passive', 'Leukocyte Count', 'Lymphocyte Activation', 'T-Lymphocytes', 'Thyroid Gland', 'Thyroiditis'] | 3,897,375 | [['B01.050'], ['C20.111'], ['G04.198', 'G07.568.500.180'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E0... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Common principle of guidance by echolocation and vision. | 1. Using echolocation, bats move as gracefully as birds through the cluttered environment, suggesting common principles of optic and acoustic guidance. We tested the idea by analysing braking control of bats (Macroderma gigas) flying through a narrow aperture with eyes covered and uncovered. 2. Though braking control w... | ['Animals', 'Chiroptera', 'Conditioning, Operant', 'Echolocation', 'Female', 'Flight, Animal', 'Food', 'Reward', 'Vision, Ocular'] | 1,494,137 | [['B01.050'], ['B01.050.150.900.649.313.937'], ['F02.463.425.179.509'], ['F01.145.113.055.400'], ['G11.427.410.568.304', 'G11.427.410.698.416'], ['G07.203.300', 'J02.500'], ['F02.463.425.770.836'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Tumor development and cytokine production by human colon tissues and carcinoma cell lines. | BACKGROUND AND OBJECTIVES: Solid tumors evade the host immunologic responses they initiate by unknown mechanisms. The authors investigated patterns of cytokine content in human colon carcinomas, colon cancer cell lines in vitro, and nude mouse xenografts from those lines in order to clarify those mechanisms.METHODS: Ep... | ['Adenocarcinoma', 'Animals', 'Colonic Neoplasms', 'Female', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Neoplasm Transplantation', 'Transforming Growth Factor beta', 'Tumor Cells, Cultured', 'Tumor Necrosis Factor-alpha'] | 12,774,340 | [['C04.557.470.200.025'], ['B01.050'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.9... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Support in suicidal crises: the Swedish National Program to Develop Suicide Prevention. The Swedish National Council for Suicide Prevention. | The Swedish National Program to Develop Suicide Prevention was created through collaboration between the National Board of Health and Welfare, the National Institute of Public Health, and the Centre for Suicide Research and Prevention. These institutions aim to provide joint support for the development of suicide preve... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Crisis Intervention', 'Guidelines as Topic', 'Health Knowledge, Attitudes, Practice', 'Humans', 'National Health Programs', 'Organizational Objectives', 'Suicide', 'Sweden'] | 9,286,129 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['F04.754.252'], ['N04.761.700.350', 'N05.700.350'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550'], ['N04.452.615'], ['F01.145.126.980.875', 'I01.880.735.856'], ['Z01.542.816.500']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Reversal of multidrug resistance by valinomycin is overcome by CCCP. | Reversal of P-glycoprotein-mediated multidrug resistance by valinomycin is overcome by the proton ionophore, CCCP. This effect, a complete suppression of the 5- to 10-fold valinomycin-induced reversal ("re-reversal"), exhibits a sharp extracellular potassium concentration ([K+(0)]) dependence. It is observed at [K+(0)]... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Carbonyl Cyanide m-Chlorophenyl Hydrazone', 'Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone', 'Coloring Agents', 'Daunorubicin', 'Drug Resistance, Multiple', 'Humans', 'Ionophores', 'KB Cells', 'Kinetics', 'Potassium', 'Rhodamine 123', 'Rhodamines', 'Vali... | 8,604,982 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D02.442.288.200', 'D02.626.260'], ['D02.442.288.220', 'D02.626.270'], ['D27.720.233'], ['D02.455.426.559.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Valpromide (Depamide) in the treatment of acute psychotic states. Open clinical study]. | In an open clinical study on the effect of Depamide in acute psychosis, 59 schizophrenic and 23 manic hospitalized patients were tested. They were divided in two groups: in group A, Depamide was administered only after an initial period of treatment with haloperidol or chlorpromazine; in group B instead, Depamide was a... | ['Acute Disease', 'Antipsychotic Agents', 'Bipolar Disorder', 'Chlorpromazine', 'Drug Therapy, Combination', 'Female', 'Haloperidol', 'Humans', 'Male', 'Schizophrenia', 'Valproic Acid'] | 2,875,606 | [['C23.550.291.125'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F03.084.500'], ['D02.886.369.198', 'D03.633.300.783.198'], ['E02.319.310'], ['D02.522.352.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.700.750'], ['D02.241.081.944.509.900', 'D10.251.400.8... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative angiographic measurements of isolated left anterior descending coronary artery stenosis. Correlation with exercise echocardiography and technetium-99m 2-methoxy isobutyl isonitrile single-photon emission computed tomography. | OBJECTIVES: This study sought to assess the value of quantitative coronary arteriography in predicting an ischemic response at exercise echocardiography and technetium-99m 2-methoxy isobutyl isonitrile (mibi) single-photon emission computed tomography (SPECT) in patients with single-vessel disease of the left anterior ... | ['Coronary Angiography', 'Coronary Disease', 'Echocardiography', 'Exercise Test', 'Female', 'Heart', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Predictive Value of Tests', 'ROC Curve', 'Sensitivity and Specificity', 'Technetium Tc 99m Sestamibi', 'Tomography, Emissio... | 7,759,695 | [['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['A07.541'], ['B01.050.150.900.649.313.988.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Functional association of nuclear protein 4.1 with pre-mRNA splicing factors. | Protein 4.1 is a multifunctional polypeptide that links transmembrane proteins with the underlying spectrin/actin cytoskeleton. Recent studies have shown that protein 4.1 is also present in the nucleus, localized in domains enriched in splicing factors. Here we further analyze the relationship between protein 4. 1 and ... | ['Animals', 'COS Cells', 'Cell Line', 'Cell Nucleus', 'Cloning, Molecular', 'Dogs', 'HeLa Cells', 'Humans', 'Nuclear Proteins', 'Protein Binding', 'RNA Precursors', 'RNA Splicing', 'Transfection'] | 9,645,944 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.393.220'], ['B01.050.150.900.649.313.750.250.216.200'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The self-care profiles and its determinants among adults with hypertension in primary health care clinics in Selangor, Malaysia. | INTRODUCTION: Self-care has been shown to improve clinical outcome of hypertension. Gauging the level of self-care among patients with hypertension enables the design of their personalized care plans. This study aimed to determine the self-care profiles and its determinants among patients with hypertension in the Malay... | ['Aged', 'Ambulatory Care Facilities', 'Cross-Sectional Studies', 'Educational Status', 'Female', 'Humans', 'Hypertension', 'Malaysia', 'Male', 'Medical History Taking', 'Middle Aged', 'Primary Health Care', 'Self Care', 'Sex Factors'] | 31,693,677 | [['M01.060.116.100'], ['N02.278.035'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['Z01.252.145.487'], ['E01.370.510'], ['M01.060.116.630'], ['N04.590.233.727'], ['E02.900', 'I03.050.563', 'N02.421.784... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Complex formation between the adenovirus DNA-binding protein and single-stranded poly(rA). Cooperativity and salt dependence. | The complex formed between adenovirus DNA-binding protein (AdDBP) and poly(rA) was investigated with circular dichroism spectroscopy. The binding process was studied at a variety of salt concentrations, and the titration curves were analyzed according to the contiguous cooperative binding model given by McGhee and von ... | ['Adenoviridae', 'Circular Dichroism', 'DNA, Single-Stranded', 'DNA-Binding Proteins', 'Poly A', 'Viral Proteins'] | 2,611,264 | [['B04.280.030'], ['E05.196.867.151'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D12.776.260'], ['D13.695.578.550.500'], ['D12.776.964']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of tumour promoters on metabolic cooperation between human hepatoma cells. | Metabolic cooperation between cells from three human hepatoma cell lines was studied by the clonogenic method and by autoradiography. It was found that human HGPRT+/HGPRT- SK-HEP-1 cells only, showed a metabolic cooperation capacity that was inhibited by tumour promoters 12-O-tetradecanoylphorbol-13-acetate (TPA) and p... | ['Carcinogens', 'Carcinoma, Hepatocellular', 'Cell Communication', 'Cell Line', 'Humans', 'Hypoxanthine Phosphoribosyltransferase', 'Liver Neoplasms', 'Phenobarbital', 'Tetradecanoylphorbol Acetate'] | 3,013,443 | [['D27.888.569.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.085'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.400.725.450'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['D03.383.742.698.253.650'], ['D02.455.849.291.50... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective bowel decontamination for the prevention of infection in acute myelogenous leukemia: a prospective randomized trial. | BACKGROUND: Infection is still a frequent cause of morbidity and mortality in acute myelogenous leukemia (AML) patients receiving chemotherapy. Recently the main cause of infection has changed from gram-negative to gram-positive bacteria and the resistance to antibiotics has increased. This study aimed to access the ef... | ['Adult', 'Anti-Infective Agents', 'Antibiotic Prophylaxis', 'Bacterial Infections', 'Ciprofloxacin', 'Drug Therapy, Combination', 'Female', 'Fever', 'Fluconazole', 'Humans', 'Incidence', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Neutropenia', 'Prospective Studies', 'Roxithromycin', 'Treatment Outcome'] | 12,014,211 | [['M01.060.116'], ['D27.505.954.122'], ['E02.319.162.150', 'E02.319.703.150'], ['C01.150.252'], ['D03.633.100.810.835.322.186'], ['E02.319.310'], ['C23.888.119.344'], ['D03.383.129.799.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A case of abdominal desmoid causing urinary tract obstruction]. | A 62-year-old male patient presented with a complaint of the lower abdominal distention. Ultrasonography demonstrated bilateral hydronephroses and a huge heterogeneous mass in the pelvic cavity. Excretory urogram showed left-non visualized kidney and right-hydronephrosis. CT showed a heterogenous mass, situating 25 cm ... | ['Abdominal Neoplasms', 'Fibromatosis, Aggressive', 'Humans', 'Hydronephrosis', 'Male', 'Middle Aged', 'Ureteral Obstruction'] | 8,533,683 | [['C04.588.033'], ['C04.557.450.565.590.340.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.307', 'C13.351.968.419.307'], ['M01.060.116.630'], ['C12.777.725.776', 'C13.351.968.725.776']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel ferredoxin-dependent glutamate synthase from the hydrogen-oxidizing chemoautotrophic bacterium Hydrogenobacter thermophilus TK-6. | Glutamate synthases are classified according to their specificities for electron donors. Ferredoxin-dependent glutamate synthases had been found only in plants and cyanobacteria, whereas many bacteria have NADPH-dependent glutamate synthases. In this study, Hydrogenobacter thermophilus, a hydrogen-oxidizing chemoautotr... | ['Bacteria', 'Bacterial Proteins', 'DNA Primers', 'Electron Spin Resonance Spectroscopy', 'Ferredoxins', 'Glutamate Synthase', 'Hydrogen', 'Kinetics', 'Molecular Sequence Data', 'Phylogeny', 'Recombinant Proteins', 'Spectrophotometry'] | 17,237,175 | [['B03'], ['D12.776.097'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.867.519.274'], ['D12.776.097.350', 'D12.776.157.427.374.375.275', 'D12.776.556.579.374.375.275', 'D12.776.765.319'], ['D08.811.682.664.500.470', 'D08.811.913.477.700.470'], ['D01.268.406', 'D01.362.340'], ['G01.374.661', 'G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Solubilization of full-length amyloid precursor proteins from PC12 cell membranes. | The amyloid beta protein (A beta) of Alzheimer disease (AD) is derived from the proteolytic processing of the amyloid precursor proteins (APP), which are considered type I transmembrane proteins. Production of A beta from a transmembrane precursor predicts a proteolytic cleavage within the lipid bilayer, a site relativ... | ['Amyloid', 'Animals', 'Aprotinin', 'Calcium', 'Cell Membrane', 'Culture Media, Conditioned', 'Hydrogen-Ion Concentration', 'Neoplasm Proteins', 'Nerve Tissue Proteins', 'PC12 Cells', 'Prions', 'Protease Inhibitors', 'Protein Precursors', 'Rats', 'Serine Endopeptidases', 'Solubility', 'Sulfones', 'Temperature', 'Zinc'] | 7,530,778 | [['D05.500.049', 'D12.776.049'], ['B01.050'], ['D12.776.083'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.149'], ['D27.720.470.305.250', 'E07.206.250'], ['G02.300'], ['D12.776.624'], ['D12.776.631'], ['A11.251.210.190.750', 'A11.251.860.180.750', 'A11.299.500'], ['D12.776.785'], ['D27.505.519.389.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transformation and physical properties of R-factor RP4 transferred from Escherichia coli to Rhizobium trifolii. | Transformation of R-factor RP4 specifying resistance to ampicillin, kanamycin, and tetracycline from Escherichia coli to Rhizobium trifolii is reported. Partially purified RP4 deoxyribonucleic acid (DNA) of the donor strain E. coli J5-3 that carried the R-factor was prepared by the lysozyme-ethylenediaminetetraacetic a... | ['Ampicillin', 'Carbon Radioisotopes', 'Centrifugation, Density Gradient', 'DNA, Bacterial', 'DNA, Circular', 'Escherichia coli', 'Kanamycin', 'Penicillin Resistance', 'Rhizobium', 'Tetracycline', 'Thymidine', 'Transformation, Genetic', 'Tritium'] | 4,584,801 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['E05.181.724.336', 'E05.196.941.336'], ['D13.444.308.212'], ['D13.444.308.283', 'G02.111.570.820.486.212', 'G05.360.580.156'], ['B03.440.450.425.325.300', 'B03.660.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early veno-venous extracorporeal membrane oxygenation is associated with lower mortality in patients who have severe hypoxemic respiratory failure: A retrospective multicenter cohort study. | PURPOSE: The purpose of the study is to compare outcomes in patients who had severe hypoxemic respiratory failure (Pao2/fraction of inspired oxygen <100) who received early veno-venous extracorporeal membrane oxygenation (ECMO) as an adjunct to mechanical ventilation, to those in patients who received conventional mech... | ['Adult', 'Blood Gas Analysis', 'British Columbia', 'Cohort Studies', 'Critical Care', 'Extracorporeal Membrane Oxygenation', 'Female', 'Hospital Mortality', 'Humans', 'Intensive Care Units', 'Logistic Models', 'Male', 'Middle Aged', 'Odds Ratio', 'Proportional Hazards Models', 'Respiration, Artificial', 'Respiratory D... | 26,971,033 | [['M01.060.116'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['Z01.107.567.176.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.760.190', 'N02.421.585.190'], ['E02.880.301', 'E04.292.451'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Forward versus backward walking: transfer of podokinetic adaptation. | We asked whether podokinetic adaptation to walking on a circular treadmill transfers to different forms of locomotion. Subjects were blindfolded and asked to walk straight across the floor, in the forward and backward directions, following podokinetic (PK) stimulation that consisted of 30 min of forward walking-in-plac... | ['Adaptation, Physiological', 'Adult', 'Aged', 'Female', 'Gait', 'Humans', 'Male', 'Middle Aged', 'Psychomotor Performance', 'Vestibule, Labyrinth', 'Walking'] | 11,600,630 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['A09.246.300.909'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans. | Nuclear migration plays an important role in the growth and development of many organisms including the multinuclear fungus Aspergillus nidulans. We have identified four genes, nudA, nudC, nudF, and nudG, in which temperature-sensitive mutations affect nuclear distribution. In this report, we describe the cloning of th... | ['Adenosine Triphosphate', 'Amino Acid Sequence', 'Animals', 'Aspergillus nidulans', 'Cell Nucleus', 'Cloning, Molecular', 'Cytoplasm', 'Dyneins', 'Genes, Fungal', 'Genetic Complementation Test', 'Molecular Sequence Data', 'Mutation', 'Phenotype', 'Restriction Mapping', 'Sequence Homology, Amino Acid', 'Temperature'] | 8,134,356 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.300.381.081.420'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.393.220'], ['A11.284.430.214'], ['D08.811.277.040.013.500.063', 'D08.811.277.040.025.024.063', 'D08.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Pineal-specific agouti protein regulates teleost background adaptation. | Background adaptation is used by teleosts as one of a variety of camouflage mechanisms for avoidance of predation. Background adaptation is known to involve light sensing by the retina and subsequent regulation of melanophore dispersion or contraction in melanocytes, mediated by á-melanocyte-stimulating hormone and mel... | ['Adaptation, Physiological', 'Agouti-Related Protein', 'Animals', 'Gene Expression Regulation', 'Melanosomes', 'Pigmentation', 'Pineal Gland', 'Receptor, Melanocortin, Type 1', 'Zebrafish'] | 20,980,662 | [['G07.025', 'G16.012.500'], ['D12.644.276.074', 'D12.776.467.074', 'D23.529.074'], ['B01.050'], ['G05.308'], ['A11.284.430.214.190.500.560', 'A11.284.430.214.190.875.190.190.560', 'A11.409.750.560', 'A11.436.265.531.560', 'A11.436.613.560'], ['E01.370.600.620', 'G16.690'], ['A06.300.635', 'A06.688.733', 'A08.186.211.1... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary pectin's effect on ileal and fecal amino acid digestibility and exocrine pancreatic secretions in growing pigs. | The effect of dietary pectin on apparent ileal and fecal digestibilities of protein and amino acids and on pancreatic secretions was studied in two experiments with growing pigs (initial weight 70 kg). Four barrows were fitted with simple T-cannulas for collection of ileal digesta; another four barrows were fitted with... | ['Amino Acids', 'Animals', 'Aspartic Acid', 'Dietary Fiber', 'Digestion', 'Feces', 'Glutamates', 'Glutamic Acid', 'Glycine', 'Ileum', 'Male', 'Pancreas', 'Pancreatic Juice', 'Pectins', 'Phenylalanine', 'Proline', 'Serine', 'Swine', 'Threonine', 'Trypsin', 'Valine', 'alpha-Amylases'] | 7,914,917 | [['D12.125'], ['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.650.250', 'G10.261.190'], ['A12.459'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D12.125.481'], ['A03.556.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Adolescents and Young Adults With Cancer: Oncology Nurses Report Attitudes and Barriers to Discussing Fertility Preservation. | BACKGROUND: Fertility issues have been found to be an important topic for adolescents and young adults (AYAs) with cancer. Medical technology has made fertility preservation (FP) increasingly effective for postpubertal patients whose treatment course may inhibit their future ability to achieve biologic parenthood. Onco... | ['Adolescent', 'Adult', 'Age Factors', 'Attitude of Health Personnel', 'Communication', 'Decision Making', 'Female', 'Fertility Preservation', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Nurse Clinicians', 'Nurse-Patient Relations', 'Oncology Nursing', 'Patient Education as T... | 27,441,525 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.100.050', 'N05.300.100'], ['F01.145.209', 'L01.143'], ['F02.463.785.373'], ['E02.875.800.625', 'E04.936.537.562', 'E05.820.800.625'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
[Subjective visual perception after laser treatment of myopia on two types of lasers]. | AIM: Comparison of subjective evaluation of patients with low and moderate myopia undergoing photorefractive keratectomy (PRK) and Laser in Situ Keratomileusis (LASIK) on two types of excimer lasers: Schwind Esiris and Schwind Amaris.PATIENTS AND METHODS: Patients were divided into two groups according to the type of l... | ['Adult', 'Female', 'Humans', 'Keratomileusis, Laser In Situ', 'Male', 'Middle Aged', 'Myopia', 'Patient Satisfaction', 'Photorefractive Keratectomy', 'Vision, Ocular', 'Young Adult'] | 21,394,978 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594.480.750', 'E04.014.520.480.750', 'E04.378.500.750', 'E04.540.825.437.374'], ['M01.060.116.630'], ['C11.744.636'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['E02.594.480.875', ... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Discharge Readiness after Tricompartment Knee Arthroplasty: Adductor Canal versus Femoral Continuous Nerve Blocks-A Dual-center, Randomized Trial. | BACKGROUND: The authors conducted a randomized, controlled, parallel-arm, superiority study to test the hypothesis that a continuous adductor canal block decreases the time to attain four discharge criteria compared with a continuous femoral nerve block after tricompartment knee arthroplasty.METHODS: Subjects undergoin... | ['Aged', 'Arthroplasty, Replacement, Knee', 'Autonomic Nerve Block', 'Catheterization', 'Catheters, Indwelling', 'Female', 'Femoral Nerve', 'Humans', 'Male', 'Middle Aged', 'Pain Measurement', 'Pain, Postoperative', 'Patient Discharge', 'Ultrasonography'] | 26,079,800 | [['M01.060.116.100'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E03.155.086.711.299', 'E04.525.210.550.500'], ['E02.148', 'E05.157'], ['E07.132.500'], ['A08.800.800.720.450.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['C23.550.767.700'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence and correlates of benzodiazepine use and misuse among young adults who use prescription opioids non-medically. | BACKGROUND: Benzodiazepine use dramatically increases the risk of unintentional overdose among people who use opioids non-medically. However, little is known about the patterns of co-occurring benzodiazepine and opioid use among young adults in the United States.METHODS: The Rhode Island Young Adult Prescription Drug S... | ['Adolescent', 'Adult', 'Analgesics, Opioid', 'Benzodiazepines', 'Cross-Sectional Studies', 'Female', 'Harm Reduction', 'Humans', 'Male', 'Mood Disorders', 'Opioid-Related Disorders', 'Prescription Drug Misuse', 'Prevalence', 'Rhode Island', 'United States', 'Young Adult'] | 29,241,103 | [['M01.060.057'], ['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D03.633.100.079.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.477'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Organ transplantations: the rights of donors. | History of organ transplantation dating back to 3500 BC is briefly surveyed as well as modern legislation with specific reference to Portugal. The importance and necessity for medical and legal certification of death is discussed as are the rights of the organ donor. | ['Death Certificates', 'Human Rights', 'Humans', 'Portugal', 'Tissue Donors', 'Transplantation'] | 2,516,192 | [['E05.318.308.940.350', 'L01.399.250.900.350', 'N04.452.859.264', 'N05.715.360.300.715.315', 'N06.850.520.308.940.350'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.727'], ['M01.898'], ['E04.936']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Diagnosis of extruded disk hernia]. | The diagnosis of an extruded prolapsed intervertebral disc is a contra-indication to chymonucleolysis. The authors tried to define the diagnosis by comparing clinical signs, radiculography and operative findings in 98 patients. There is no characteristic clinical sign. On radiculography, there is no pathognomonic sign ... | ['Diagnosis, Differential', 'Humans', 'Intervertebral Disc Displacement', 'Radiography'] | 7,156,821 | [['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['E01.370.350.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment of growth failure with human growth hormone in patients with juvenile chronic arthritis. A pilot study. | Six children with JCA and one with SLE, aged 11.7 to 17.1 years, have been treated with human growth hormone (hGH) for six months to three years because of growth retardation. Their height SDS score ranged from -2.4 to -6.4. All have been treated with corticosteroids for 8.4 years on average. The doses of prednisolone ... | ['Adolescent', 'Arthritis, Juvenile', 'Body Height', 'Child', 'Female', 'Growth', 'Growth Disorders', 'Growth Hormone', 'Humans', 'Male', 'Pilot Projects', 'Puberty', 'Time Factors'] | 2,060,178 | [['M01.060.057'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['M01.060.406'], ['G07.345.249'], ['C23.550.393'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Whole genome sequencing reveals an outbreak of Salmonella Enteritidis associated with reptile feeder mice in the United Kingdom, 2012-2015. | Analysis of whole genome sequencing data uncovered a previously undetected outbreak of Salmonella Enteritidis that had been on-going for four years. Cases were resident in all countries of the United Kingdom and 40% of the cases were aged less than 11 years old. Initial investigations revealed that 30% of cases reporte... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Child', 'Child, Preschool', 'Disease Outbreaks', 'Feeding Behavior', 'Female', 'Genome, Bacterial', 'Humans', 'Infant', 'Male', 'Mice', 'Middle Aged', 'Phylogeny', 'Rats', 'Salmonella Infections', 'Salmonella enteritidis', 'Snakes', 'United Kingdom', 'Who... | 29,366,466 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.290'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['G05.360.340.358.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
A behind-the-numbers look at rising Rx costs. | Spending more on drugs saves health care dollars, by heading off complications of chronic disease. That was the conventional wisdom--until spiraling costs convinced cost-conscious employers to take a closer look at the pharmacy budget. | ['Advertising', 'Chronic Disease', 'Cost Control', 'Drug Costs', 'Employer Health Costs', 'Health Maintenance Organizations', 'Humans', 'Insurance, Pharmaceutical Services', 'United States'] | 10,177,023 | [['J01.219.687.274', 'L01.143.050'], ['C23.550.291.500'], ['N03.219.151.160'], ['N03.219.151.400.350', 'N05.300.375.300'], ['N03.219.151.400.375', 'N05.300.375.350'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
MODIFIED HEIDELBERG TECHNIQUE FOR PANCREATIC ANASTOMOSIS. | BACKGROUND: Pancreatic fistula is a major cause of morbidity and mortality after pancreatoduodenectomy. To prevent this complication, many technical procedures have been described.AIM: To present a novel technique based on slight modifications of the original Heidelberg technique, as new pancreatojejunostomy technique ... | ['Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Fistula', 'Pancreaticoduodenectomy', 'Pancreaticojejunostomy', 'Postoperative Complications'] | 29,340,550 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.267.775', 'C06.689.583', 'C23.300.575.185.775'], ['E04.210.760'], ['E04.035.703', 'E04.210.762'], ['C23.550.767']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The influence of motor vehicle legislation on injury claim incidence. | BACKGROUND: Although there have been numerous strategies to prevent motor vehicle collisions and their subsequent injuries, few have been effective in preventing motor vehicle injury claims. In this paper, we examine the role of legislation and compensation system in altering injury claim incidence.METHODS: The populat... | ['Accidents, Traffic', 'Automobile Driving', 'Canada', 'Humans', 'Insurance Claim Reporting', 'Insurance, Liability', 'Wounds and Injuries'] | 15,682,700 | [['N06.850.135.392'], ['I03.125'], ['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.210'], ['N03.219.521.576.443'], ['C26']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Aspects of esophageal atresia in a population-based setting: incidence, mortality, and cancer risk. | PURPOSE: To estimate the incidence, mortality and cancer risk of the congenital malformation esophageal atresia (EA) in a population-based investigation.METHODS: A population-based cohort study of EA patients registered in three nationwide registers in Sweden in 1964-2007. The incidence of EA per total number of live b... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Confidence Intervals', 'Esophageal Atresia', 'Esophageal Neoplasms', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Population Surveillance', 'Prognosis', 'Proportional Hazards Models', 'Registries', 'Retrospective Studies', 'Risk Assessment'... | 22,020,495 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C06.198.330', 'C06.405.117.260', 'C16.131.314.330'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Does the prevention of complications explain the survival benefit of organized inpatient (stroke unit) care?: further analysis of a systematic review. | BACKGROUND AND PURPOSE: Systematic reviews have shown that organized inpatient (stroke unit) care reduces the risk of death after stroke. However, it is unclear how this is achieved. We tested whether stroke unit care could reduce deaths by preventing complications.METHODS: We updated a collaborative systematic review ... | ['Hospital Units', 'Hospitalization', 'Humans', 'Inpatients', 'Randomized Controlled Trials as Topic', 'Stroke', 'Survival Analysis', 'Treatment Outcome'] | 17,690,313 | [['N02.278.388'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['C10.228.140.300.775', 'C14.907.253.855'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.5... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Suffering and pleasure in the process of forming multidisciplinary health residents]. | OBJECTIVE: to identify situations of pleasure and suffering in the process of training multidisciplinary health resident.METHOD: qualitative research, developed in the Multiprofessional Residence Program in Health at a university from the south of Brazil. Data was collected in 2013 through focus groups with nine reside... | ['Health Personnel', 'Humans', 'Pleasure', 'Stress, Psychological'] | 26,735,764 | [['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.867', 'F02.830.816.492'], ['F01.145.126.990', 'F02.830.900']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Outpatient treatment in German adolescents with depression: an analysis of nationwide health insurance data. | PURPOSE: Data on medical treatment of adolescents with depression are scarce. This study aimed to examine outpatient health services utilisation of depressive disorders in adolescents.METHODS: Data of a statutory health insurance company were analysed and outpatients from 12 to 18 years old with diagnosed depression du... | ['Adolescent', 'Age Factors', 'Ambulatory Care', 'Antidepressive Agents', 'Child', 'Combined Modality Therapy', 'Cross-Sectional Studies', 'Databases, Factual', 'Depressive Disorder', 'Female', 'Germany', 'Guideline Adherence', 'Humans', 'Male', 'Practice Guidelines as Topic', 'Psychotherapy', 'Sex Factors'] | 22,639,197 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['E02.760.106', 'N02.421.585.106'], ['D27.505.954.427.700.122'], ['M01.060.406'], ['E02.186'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['F03.600.300'], ['Z01.542.315'], ['... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Changes in the prevalence of overweight and obesity: some evidence from the Swiss Health Surveys 1992/93 and 2002. | BACKGROUND: This study examines changes in the prevalence of overweight and obesity in the Swiss general population from 1992/93 to 2002 and their relationship with changes in the distribution and effect of socioeconomic and health behavioural risk factors.METHODS: Cross-sectional data from telephone interviews of the ... | ['Adult', 'Aged', 'Body Mass Index', 'Cross-Sectional Studies', 'Female', 'Health Behavior', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Overweight', 'Prevalence', 'Risk Factors', 'Sex Factors', 'Socioeconomic Factors', 'Switzerland', 'Young Adult'] | 19,887,519 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.488'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Student experiences and mentor views of the use of simulation for learning. | This paper presents the findings of a two phase mixed methods study. Phase 1 investigated whether simulation could support the development of a range of clinical skills amongst pre-registration adult and children's nursing students. The second phase of the study gathered mentors' views and experiences of the use of sim... | ['Attitude of Health Personnel', 'Clinical Competence', 'Curriculum', 'Education, Nursing, Baccalaureate', 'Educational Measurement', 'Faculty, Nursing', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Life Support Care', 'Lifting', 'Mentors', 'Nursing Education Research', 'Nursing Methodology Research', 'Patient S... | 18,479,785 | [['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.462.316'], ['I02.399'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.440', 'N02.421.585.440'], ['G01... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Techno... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Cell surface glycoproteins of 13762NF mammary adenocarcinoma clones of differing metastatic potentials. | Rat 13762NF mammary adenocarcinoma cell surface glycoproteins from s.c. tumor- or lung metastases-derived cell clones of differing spontaneous metastatic potentials were examined for their relationship to metastasis. After treatment with neuraminidase, lectin-binding assays showed that highly metastatic clone MTLn3 cel... | ['Adenocarcinoma', 'Animals', 'Arachis', 'Binding Sites', 'Clone Cells', 'Concanavalin A', 'Glycoproteins', 'Lectins', 'Mammary Neoplasms, Experimental', 'Membrane Proteins', 'Mice', 'Neoplasm Metastasis', 'Neoplasm Proteins', 'Peanut Agglutinin', 'Plant Lectins', 'Sialoglycoproteins', 'Surface Properties', 'Wheat Germ... | 6,688,589 | [['C04.557.470.200.025'], ['B01.050'], ['B01.650.940.800.575.912.250.401.077'], ['G02.111.570.120'], ['A11.251.353'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D09.400.430', 'D12.776.395'], ['D12.776.503'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['D12.776.543'], ['B01.050.150.900.649.313.992... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phytochrome from Agrobacterium tumefaciens has unusual spectral properties and reveals an N-terminal chromophore attachment site. | Phytochromes are photochromic photoreceptors with a bilin chromophore that are found in plants and bacteria. The soil bacterium Agrobacterium tumefaciens contains two genes that code for phytochrome-homologous proteins, termed Agrobacterium phytochrome 1 and 2 (Agp1 and Agp2). To analyze its biochemical and spectral pr... | ['Agrobacterium tumefaciens', 'Amino Acid Sequence', 'Base Sequence', 'Binding Sites', 'DNA Primers', 'Molecular Sequence Data', 'Molecular Structure', 'Mutation', 'Phosphorylation', 'Phytochrome', 'Sequence Homology, Amino Acid'] | 12,186,972 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['G05.365.590'], ['G02.111... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Roles of the Excitation in Harvesting Energy from Vibrations. | The study investigated the role of excitation in energy harvesting applications. While the energy ultimately comes from the excitation, it was shown that the excitation may not always behave as a source. When the device characteristics do not perfectly match the excitation, the excitation alternately behaves as a sourc... | ['Energy Transfer', 'Vibration'] | 26,496,183 | [['G01.154.240', 'G02.111.255', 'G02.216'], ['G01.374.930']] | ['Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cooperated biotransformation of ginsenoside extracts into ginsenoside 20(S)-Rg3 by three thermostable glycosidases. | AIMS: The aim of this work was to transform ginsenoside extract into the pharmacologically active minor ginsenoside 20(S)-Rg3 by three thermostable glycosidases.METHODS AND RESULTS: The GH1 thermostable beta-glucosidase Tpebgl1 from Thermotoga petrophlia was found to have the ability to convert ginsenosides Rb1 and Rb2... | ['Bacteria', 'Biotransformation', 'Enzyme Stability', 'Ginsenosides', 'Plant Extracts', 'Temperature', 'beta-Glucosidase'] | 31,715,079 | [['B03'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.916.360', 'G02.111.700.500'], ['D02.455.849.919.277', 'D09.408.782.300'], ['D20.215.784.500', 'D26.667'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D08.811.277.450.420.200.100']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Nest site attributes and temporal patterns of northern flicker nest loss: effects of predation and competition. | To date, most studies of nest site selection have failed to take into account more than one source of nest loss (or have combined all sources in one analysis) when examining nest site characteristics, leaving us with an incomplete understanding of the potential trade-offs that individuals may face when selecting a nest... | ['Animals', 'Birds', 'Competitive Behavior', 'Ecosystem', 'Nesting Behavior', 'Predatory Behavior', 'Reproduction', 'Time Factors'] | 16,323,016 | [['B01.050'], ['B01.050.150.900.248'], ['F01.145.813.105'], ['G16.500.275.157', 'N06.230.124'], ['F01.145.113.252.478'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['G08.686.784'], ['G01.910.857']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Atomic decomposition of the protein solvation free energy and its application to amyloid-beta protein in water. | We report the development of an atomic decomposition method of the protein solvation free energy in water, which ascribes global change in the solvation free energy to local changes in protein conformation as well as in hydration structure. So far, empirical decomposition analyses based on simple continuum solvation mo... | ['Amyloid beta-Peptides', 'Models, Molecular', 'Molecular Dynamics Simulation', 'Protein Conformation', 'Protein Unfolding', 'Water'] | 21,787,012 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['E05.599.595'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709'], ['G01.154.651.750', 'G02.111.688.750'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Safety investigation of team performance in accidents. | The paper presents the capacities of the performance evaluation of teamwork (PET) method. Its practicability and efficiency are illustrated by retrospective human reliability analyse of the famous nuclear and maritime accidents. A quantitative assessment of operators' performance on the base of thermo-hydraulic (T/H) c... | ['Disaster Planning', 'Humans', 'Institutional Management Teams', 'Models, Organizational', 'Pilot Projects', 'Radioactive Hazard Release', 'Retrospective Studies', 'Risk Assessment', 'Safety Management', 'Task Performance and Analysis'] | 15,231,353 | [['N06.230.100.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.460'], ['E05.599.670', 'N04.452.534'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['N06.850.135.848'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.36... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Electrochemical measurement of endogenous serotonin release from human blood platelets. | Platelet aggregation in the bloodstream is tightly associated with the secretory function of platelets based on several types of cytoplasmic secretory granules, each sequestering distinct chemical messenger species. Dense-body granules are one prominent type of secretory granule responsible for storing small molecule c... | ['Blood Platelets', 'Carbon', 'Carbon Fiber', 'Electrochemistry', 'Electrodes', 'Hermanski-Pudlak Syndrome', 'Humans', 'Serotonin', 'Suspensions'] | 21,384,903 | [['A11.118.188', 'A15.145.229.188'], ['D01.268.150'], ['D01.268.150.038', 'D05.750.139', 'D25.720.150', 'J01.637.051.720.150'], ['H01.181.529.307'], ['E07.305.250'], ['C11.270.040.545.400', 'C15.378.100.100.515', 'C15.378.100.685.400', 'C15.378.140.735.400', 'C15.378.463.735.400', 'C16.320.099.515', 'C16.320.290.040.10... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Headache as a symptom of angina]. | The authors report two cases where headaches was the only manifestation of severe myocardial ischemia. They had high degree coronaria sclerosis which was demonstrated by angiocardiography in one patient and at autopsy in the second patient. These findings suggest that in the mechanism of headache angina rather the pain... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angina Pectoris', 'Angiocardiography', 'Angioplasty, Balloon, Coronary', 'Coronary Angiography', 'Echocardiography', 'Electrocardiography', 'Headache', 'Humans', 'Male', 'Myocardial Ischemia'] | 9,432,643 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E01.370.350.130.249', 'E01.370.350.700.060.050', 'E01.370.370.050.050', 'E01.370.370.380.050'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFbeta3 and their receptors in cultured uterine leiomyoma cells. | BACKGROUND: This study was conducted to evaluate the effects of a novel selective progesterone receptor modulator (SPRM) asoprisnil on the expression of growth factors and their receptors and on growth factor-induced proliferation of cultured uterine leiomyoma and matching myometrial cells.METHODS: The expression of ep... | ['Adult', 'Blotting, Western', 'Cell Proliferation', 'Cells, Cultured', 'Down-Regulation', 'Epidermal Growth Factor', 'ErbB Receptors', 'Estrenes', 'Female', 'Gene Expression', 'Humans', 'Insulin-Like Growth Factor I', 'Leiomyoma', 'Middle Aged', 'Myometrium', 'Oximes', 'Proteoglycans', 'Receptor, IGF Type 1', 'Recepto... | 16,613,890 | [['M01.060.116'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D08.811.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of methadone on free feeding in satiated rats. | A variety of opioids and opiates are known to increase short-term food intake. In the present study, we evaluated the effects of methadone on free feeding in satiated rats. We assessed the effect of methadone (0, 1.5, 3.0, 5.0, and 10.0 mg/kg) on food intake 1, 2, 4, and 6 h after injection for 3 consecutive days. Two ... | ['Animals', 'Body Temperature', 'Drug Tolerance', 'Feeding Behavior', 'Male', 'Methadone', 'Rats', 'Rats, Sprague-Dawley', 'Satiety Response'] | 1,475,284 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G07.690.773.992'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D02.522.675'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['F02.830.749.658']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identical genomic organization of two hemichordate hox clusters. | Genomic comparisons of chordates, hemichordates, and echinoderms can inform hypotheses for the evolution of these strikingly different phyla from the last common deuterostome ancestor. Because hox genes play pivotal developmental roles in bilaterian animals, we analyzed the Hox complexes of two hemichordate genomes. We... | ['Animals', 'Biological Evolution', 'Chordata, Nonvertebrate', 'Genes, Homeobox', 'Genome', 'Molecular Sequence Data', 'Multigene Family', 'Phylogeny', 'Transcription, Genetic'] | 23,063,438 | [['B01.050'], ['G05.045', 'G16.075'], ['B01.050.150.200', 'B01.050.500.272'], ['G05.360.340.024.340.230.500'], ['G05.360.340'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.873', 'G05.297.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Atomic force microscopy of Precambrian microscopic fossils. | Atomic force microscopy (AFM) is a technique used routinely in material science to image substances at a submicron (including nm) scale. We apply this technique to analysis of the fine structure of organic-walled Precambrian fossils, microscopic sphaeromorph acritarchs (cysts of planktonic unicellular protists) permine... | ['Animals', 'Biological Evolution', 'Fossils', 'Kazakhstan', 'Microscopy, Atomic Force', 'Plankton', 'Polycyclic Aromatic Hydrocarbons', 'Time Factors'] | 12,089,337 | [['B01.050'], ['G05.045', 'G16.075'], ['I01.076.368.584.311'], ['Z01.252.100.420', 'Z01.542.931.440', 'Z01.586.950.440'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['B05.080.500'], ['D02.455.426.559.847', 'D04.615'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Flux balance analysis of a genome-scale yeast model constrained by exometabolomic data allows metabolic system identification of genetically different strains. | A systems approach to biology requires a principled approach to pathway identification. In this study, the two nuclear petite yeast mutants K1Deltapet191a and K1Deltapet191ab and their parental industrial strain K1 were cultured in glucose-containing microaerobic chemostats. Exometabolomic profiles were used to infer t... | ['Chromosome Mapping', 'Computer Simulation', 'Genetic Variation', 'Models, Biological', 'Proteome', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Signal Transduction', 'Species Specificity'] | 17,373,823 | [['E05.393.183'], ['L01.224.160'], ['G05.365'], ['E05.599.395'], ['D12.776.817'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['G02.111.820', 'G04.835'], ['G16.824']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Complete and permanent regression of persistent uveitic cystoid macular edema after single intravitreal iniection of aflibercept in patient previously treated with multiple intravitreal injections of ranibizumab and bevacizumab]. | A case report of a twenty-year-old man with quiescent, idiopathic intermediate uveitis in his right eye treated with systemic corticosteroids and persistent cystoid macular edema, admitted for further treatment due to chronic reduction in visual acuity, is presented. A therapy involving intravitreal injections of ranib... | ['Antibodies, Monoclonal, Humanized', 'Bevacizumab', 'Drug Therapy, Combination', 'Follow-Up Studies', 'Humans', 'Injections, Intraocular', 'Macular Edema', 'Male', 'Ranibizumab', 'Receptors, Vascular Endothelial Growth Factor', 'Recombinant Fusion Proteins', 'Remission Induction', 'Treatment Outcome', 'Visual Acuity',... | 26,349,156 | [['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D12.776.124.486.485.114.224.060.375', 'D12.776.124.790.651.114.224.060.438', 'D12.776.377.715.548.114.224.200.438'], ['E02.319.310'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantitative ultrasound at the hand phalanges in 2850 females aged 7 to 77 yr: a cross-sectional study. | In the study, skeletal status was evaluated in 2850 females aged 7 to 77 yr using quantitative ultrasound (QUS amplitude-dependent speed of sound [Ad-SoS]). Ad-SoS ranged from 1923 +/- 30 to 1876 +/- 81 m/s, and the peak value (2121 m/s) was achieved in 19-yr-old females. Ad-SoS increased significantly between subgroup... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Child', 'Cross-Sectional Studies', 'Female', 'Finger Phalanges', 'Humans', 'Middle Aged', 'Poland', 'Regression Analysis', 'Statistics, Nonparametric', 'Ultrasonography'] | 15,908,710 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A02.835.232.087.319.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.248.679'], ['E05.318.740.750', 'N05.715.36... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
OKT3E, an anti-CD3 antibody that does not elicit side effects or antiidiotype responses in chimpanzees. | Chimpanzees were injected with OKT3 and two other anti-CD3 antibodies, OKT3D and OKT3E. Both of the new antibodies were of the mouse IgG2b isotype. Administration of the antibodies was identical to the clinical regimen used for OKT3 in humans: 5 mg i.v., daily for 10 consecutive days. All animals were monitored for fev... | ['Animals', 'Antibodies, Anti-Idiotypic', 'Antibodies, Monoclonal', 'Antigens, Differentiation, T-Lymphocyte', 'CD3 Complex', 'Epitopes', 'Immunoglobulin G', 'Lymphocytes', 'Lymphokines', 'Mice', 'Pan troglodytes', 'Receptors, Antigen, T-Cell'] | 1,718,067 | [['B01.050'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['D23.050.550'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prognostic factors from a long-term follow-up of heroin-assisted treatment in Switzerland 1994-2007]. | OBJECTIVE: To identify prognostic factors for a positive or negative termination of heroin-assisted treatment (HAT) in Switzerland.METHOD: A complete census of all 3155 patients ever admitted was analysed using the proportional hazard model (including time dependent covariates).RESULTS: Median length of stay was 11.4 y... | ['Adult', 'Comorbidity', 'Crime', 'Female', 'Follow-Up Studies', 'HIV Seropositivity', 'Heroin', 'Humans', 'Length of Stay', 'Male', 'Models, Statistical', 'Narcotics', 'Opioid-Related Disorders', 'Outcome and Process Assessment, Health Care', 'Patient Dropouts', 'Prognosis', 'Secondary Prevention', 'Socioeconomic Fact... | 20,148,381 | [['M01.060.116'], ['N05.715.350.225', 'N06.850.490.687'], ['I01.198.240', 'I01.880.735.191'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500', 'C20.67... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Contribution of dual CD13/CD14 markers in combination with CD34 for the collection of peripheral hematopoietic stem cells]. | We evaluated the reliability of a flow cytometry technique for counting mononuclear cells (MNCs) in cytapheresis products. Eighty freshly-prepared samples of peripheral stem cells were studied using a dual immunolabeling technique with antibodies to CD13/CD14, and were also labeled with anti-CD34. Results of this immun... | ['Antigens, CD34', 'Biomarkers', 'Blood Cell Count', 'CD13 Antigens', 'Flow Cytometry', 'Hematopoietic Stem Cells', 'Hodgkin Disease', 'Humans', 'Lipopolysaccharide Receptors', 'Lymphoma, Non-Hodgkin', 'Multiple Myeloma'] | 9,538,476 | [['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D23.101'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['D08.811.277.656.350.100.160', 'D08.811.277.656.350.555.100', 'D08.811.277.656.675.555.100', 'D23.050.301.264.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aging elevates metabolic gene expression in brain cholinergic neurons. | The basal forebrain (BF) cholinergic system is selectively vulnerable in human brain diseases, while the cholinergic groups in the upper pons of the brainstem (BS) resist neurodegeneration. Cholinergic neurons (200 per region per animal) were laser-microdissected from five young (8 months) and five aged (24 months) F34... | ['Acetylcholine', 'Aging', 'Animals', 'Brain', 'Gene Expression Regulation', 'Nerve Tissue Proteins', 'Neurons', 'Prosencephalon', 'Rats', 'Rats, Inbred F344', 'Up-Regulation'] | 17,560,690 | [['D02.092.211.111'], ['G07.345.124'], ['B01.050'], ['A08.186.211'], ['G05.308'], ['D12.776.631'], ['A08.675', 'A11.671'], ['A08.186.211.200'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.200', 'B01.050.150.900.649.313.992.635.505.700.400.200'], ['G02.111.905', 'G05.308.850', 'G07.690.773.998... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis. | The contractile activity, the threshold for calcium-induced calcium release in fractions of sarcoplasmic reticulum and the potassium concentration were determined in preparations of semimembranosus muscle from normal quarter horses and quarter horses with hyperkalaemic periodic paralysis before and after they were trea... | ['Animals', 'Caffeine', 'Calcium', 'Halothane', 'Horse Diseases', 'Horses', 'Hyperkalemia', 'Muscle Contraction', 'Muscle, Skeletal', 'Paralysis', 'Phenytoin', 'Potassium'] | 7,659,842 | [['B01.050'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.455.526.340'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C18.452.950.396'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['C10.597.622', 'C23.888.592.636'], ['D03.383.129.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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