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Sonographically measured hyoid bone displacement during swallow in preschool children: a preliminary study. | PURPOSE: This study explored normative parameters regarding maximum displacement of hyoid bone movement during spontaneous swallows using ultrasound (US) in a sample of healthy preschool children. We hypothesized that consistency and bolus size would influence hyoid movement, but gender would not be a factor.METHODS: P... | ['Child, Preschool', 'Deglutition', 'Female', 'Humans', 'Hyoid Bone', 'Male', 'Sex Factors', 'Surveys and Questionnaires', 'Ultrasonography'] | 20,725,945 | [['M01.060.406.448'], ['G10.261.178'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.409'], ['N05.715.350.675', 'N06.850.490.875'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['E01.370.350.850']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Parent Recommendations for Family Functioning With Prader-Willi Syndrome: A Rare Genetic Cause of Childhood Obesity. | UNLABELLED: Prader-Willi syndrome (PWS) is the most common genetic cause of childhood obesity. Neonates have hypotonia and may fail to growth and develop. Within a few years, behavioral problems occur along with insatiable hunger (hyperphagia) and the potential for excessive weight gain. The purpose of this study was t... | ['Adult', 'Child', 'Child, Preschool', 'Family Relations', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Infant', 'Infant, Newborn', 'Interviews as Topic', 'Male', 'Middle Aged', 'Needs Assessment', 'Nursing Research', 'Parents', 'Pediatric Obesity', 'Prader-Willi Syndrome', 'Qualitative Research', 'Quality... | 26,684,080 | [['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['F01.829.263.370', 'I01.880.853.150.439'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occ... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Sleep Deprivation and Chronic Health Conditions Among Sexual Minority Adults. | OBJECTIVES: To examine associations between sleep duration and health outcomes among distinct groups of sexual minority adults.METHODS: Using data from the 2014 Behavioral Risk Factor Surveillance System, we compared sleep duration (very short: ? 5 hr; short: 6 hr; normal: 7-8 hr; and long: ? 9 hr per day) between cisg... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Male', 'Sexual and Gender Minorities', 'Sleep Deprivation', 'Young Adult'] | 28,657,361 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.777'], ['C10.886.425.175', 'C23.888.592.796.772', 'F02.830.855.671', 'F03.870.400.099'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Photodynamic effects on Fonsecaea monophora conidia and RAW264.7 in vitro. | Chromoblastomycosis (CBM), one of the neglected tropical diseases, is hard to cure and easy to be recurrent. Many studies suggest that macrophage is involved in the pathogenesis of chromoblastomycosis and the fungicidal effect of 5-Aminolaevulinic Acid-Based Photodynamic Therapy (ALA-PDT) against F. monophora (one of t... | ['Aminolevulinic Acid', 'Animals', 'Apoptosis', 'Ascomycota', 'Chromoblastomycosis', 'Light', 'Mice', 'Mitochondria', 'Photochemotherapy', 'Photosensitizing Agents', 'RAW 264.7 Cells', 'Reactive Oxygen Species', 'Spores, Fungal'] | 28,992,604 | [['D02.241.755.547.276', 'D12.125.262'], ['B01.050'], ['G04.146.954.035'], ['B01.300.107'], ['C01.150.703.302.110', 'C01.800.200.110', 'C17.800.838.208.241'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.430.214.190.875.564', 'A11.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
More attention should be paid to the formation of attitudes in doctors. | The scientific explosion of the second half of this century has led in the medical field to a process of specialization and sub-specialization, with heavy emphasis on knowledge and technical skills and neglect of the traditional humane and interpersonal aspects of the practice of medicine. An important part of clinical... | ['Attitude of Health Personnel', 'Clinical Competence', 'Humans', 'Physicians'] | 2,095,451 | [['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.810', 'N02.360.810']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Serial assessment of left-ventricular function using tissue Doppler imaging in premature infants within 7 days of life. | Although many echocardiographic parameters can assess cardiac function noninvasively in preterm infants, it has not been determined what indices are the best. We assessed left-ventricular performance in 101 very low-birth weight (VLBW) infants using tissue Doppler imaging (TDI) echocardiography. Echocardiographic exami... | ['Blood Flow Velocity', 'Echocardiography, Doppler', 'Female', 'Follow-Up Studies', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases', 'Infant, Very Low Birth Weight', 'Male', 'Reproducibility of Results', 'Retrospective Studies', 'Ventricular Dysfunction, Left', 'Ventricular Function, Lef... | 23,475,256 | [['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A monoclonal antibody to the human epidermal growth factor receptor. | A monoclonal antibody of the IgG class, EGFR1, has been isolated using cells of the epidermoid carcinoma line A431 as immunogen. The A431 antigen recognized by EGFR1 has an apparent molecular weight of approximately 175,000, is a cell-surface molecule which can be specifically cross-linked to EGF, exhibits an EGF-stimu... | ['Antibodies, Monoclonal', 'Chromosome Mapping', 'Chromosomes, Human, 6-12 and X', 'Epidermal Growth Factor', 'Epitopes', 'ErbB Receptors', 'Fluorescent Antibody Technique', 'Genes', 'Humans', 'Hybridomas', 'Immunoglobulin G', 'Receptors, Cell Surface'] | 6,188,757 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.393.183'], ['A11.284.187.520.300.325', 'G05.360.162.520.300.325'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D23.050.550'], ['D08.811.913.696.620.682.725.400.009', 'D12.776... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Controlled release from magnetoliposomes aqueous suspensions exposed to a low intensity magnetic field. | Recently, the use of liposomes loaded with magnetic nanoparticles (magnetoliposomes, (MLs)) has been intensely growing as a new drug delivery system. With the use of alternating magnetic fields, it is possible to remotely control the delivery of a drug or any other macromolecule loaded inside the MLs. In this experimen... | ['Delayed-Action Preparations', 'Drug Delivery Systems', 'Liposomes', 'Magnetic Fields', 'Metal Nanoparticles', 'Pilot Projects', 'Temperature'] | 24,482,311 | [['D26.255.210', 'E02.319.300.253'], ['E02.319.300'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['G01.358.750'], ['J01.637.512.600.500'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Synchronous bilateral renal cell carcinoma: total surgical excision. | Sixty-one patients with bilateral synchronous renal cell carcinoma have undergone total excision of their neoplastic disease. True follow-up of the patients has been obtained from the surgeons or the patients themselves. Fifty-one patients underwent renal parenchymal-sparing procedures in one- or two-stage operations. ... | ['Adenocarcinoma', 'Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Kidney Neoplasms', 'Male', 'Methods', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Nephrectomy', 'Prognosis'] | 7,438,012 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Incidence and predictors of sudden arrhythmic death or ventricular tachyarrhythmias after acute coronary syndrome: An asian perspective. | BACKGROUND: Current data on the risk of sudden arrhythmic death (SAD) and ventricular tachyarrhythmias (VTs) after acute coronary syndrome (ACS) in the Asian population are limited.OBJECTIVE: The purpose of this study was to investigate the incidence and predictors of SAD or VT after ACS in a contemporary cohort of Chi... | ['Acute Coronary Syndrome', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Death, Sudden, Cardiac', 'Female', 'Hong Kong', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Proportional Hazards Models', 'Retrospective Studies', 'Risk Assessment', '... | 27,641,793 | [['C14.280.647.124', 'C14.907.585.124'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.383.220', 'C23.550.260.322.250'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.... | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Comparisons of Noninvasive Methods Used to Assess Exercise Stroke Volume in Heart Failure with Preserved Ejection Fraction. | INTRODUCTION: Cardiopulmonary exercise testing (CPET) plays an important role in properly phenotyping signs and symptoms of heart failure with preserved ejection fraction (HFpEF). The prognostic value of CPET is strengthened when accompanied by cardiac hemodynamic measurements. Although recognized as the "gold" standar... | ['Acetylene', 'Aged', 'Breath Tests', 'Echocardiography', 'Exercise Test', 'Female', 'Heart Failure', 'Heart Function Tests', 'Humans', 'Male', 'Middle Aged', 'Oxygen', 'Oxygen Consumption', 'Reproducibility of Results', 'Stroke Volume'] | 28,471,812 | [['D02.455.326.397.259'], ['M01.060.116.100'], ['E01.370.100'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['C14.280.434'], ['E01.370.370.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D01.268.185.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A 74-year-old woman with diabetes. | Ms M, a 74-year-old woman with type 2 diabetes of 6 years' duration, has a glycated hemoglobin (HbA1C) value of 7.4% despite taking 3 oral antidiabetic medications, as well as coexistent hypertension and abdominal obesity. She has no known microvascular or macrovascular complications of diabetes and is otherwise health... | ['Aged', 'Diabetes Mellitus, Type 2', 'Disease Progression', 'Female', 'Humans', 'Hypoglycemic Agents', 'Insulin'] | 17,213,403 | [['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of Toe Type on Static Balance in Ballet Dancers. | OBJECTIVES: Some forefoot shapes are ideal for pointe work in ballet. Egyptian-type, with the hallux being longest and the remaining toes decreasing in size, and Greek-type, with the second toe longer than the hallux, are considered less optimal for pointe work. Square-type, with the second toe the same length as the h... | ['Dancing', 'Foot', 'Hallux', 'Humans', 'Postural Balance', 'Toes'] | 32,135,003 | [['I03.450.642.287'], ['A01.378.610.250'], ['A01.378.610.250.300.792.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['A01.378.610.250.300.792']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates. | Purpose: To compare the effects of both injectable anesthesia (ketamine/dexmedetomidine versus ketamine/xylazine) and inhalant anesthesia (isoflurane) on IOP using continuous, bilateral IOP telemetry in nonhuman primates (NHP).Methods: Bilateral IOP was recorded continuously using a proven implantable telemetry system ... | ['Anesthesia', 'Anesthetics, Combined', 'Anesthetics, Dissociative', 'Anesthetics, Inhalation', 'Animals', 'Dexmedetomidine', 'Intraocular Pressure', 'Isoflurane', 'Ketamine', 'Macaca mulatta', 'Male', 'Telemetry', 'Tonometry, Ocular', 'Xylazine'] | 31,529,079 | [['E03.155'], ['D27.505.696.277.100.017', 'D27.505.954.427.210.100.017'], ['D27.505.696.277.100.035.075.035', 'D27.505.954.427.210.100.035.075.035'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['B01.050'], ['D03.383.129.308.245'], ['G14.440'], ['D02.355.601.570'], ['D02.455.426.392.368.367.652'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vivo suppression of microRNA-24 prevents the transition toward decompensated hypertrophy in aortic-constricted mice. | RATIONALE: During the transition from compensated hypertrophy to heart failure, the signaling between L-type Ca(2+) channels in the cell membrane/T-tubules and ryanodine receptors in the sarcoplasmic reticulum becomes defective, partially because of the decreased expression of a T-tubule-sarcoplasmic reticulum anchorin... | ['Animals', 'Aortic Stenosis, Subvalvular', 'Calcium Channels, L-Type', 'Calcium Signaling', 'Disease Progression', 'Drug Evaluation, Preclinical', 'Excitation Contraction Coupling', 'Gene Expression Regulation', 'Heart Failure', 'Hypertrophy, Left Ventricular', 'Male', 'Membrane Proteins', 'Mice', 'Mice, Inbred C57BL'... | 23,307,820 | [['B01.050'], ['C14.280.484.048.750.070', 'C14.280.955.249.070'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['C23.550.291.656'], ['E05.290.750', 'E05.337.550'], ['G02.111.820.800.100.500', 'G04.835.199', ... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anthocyanins encapsulated by PLGA@PEG nanoparticles potentially improved its free radical scavenging capabilities via p38/JNK pathway against Aâ1-42 | BACKGROUND: In order to increase the bioavailability of hydrophilic unstable drugs like anthocyanins, we employed a polymer-based nanoparticles approach due to its unique properties such as high stability, improved bioavailability and high water-soluble drug loading efficiency. Anthocyanins constitute a subfamily of fl... | ['Alzheimer Disease', 'Amyloid beta-Peptides', 'Anthocyanins', 'Biological Availability', 'Cell Culture Techniques', 'Cell Line', 'Cell Survival', 'Drug Delivery Systems', 'Drug Liberation', 'Free Radical Scavengers', 'Humans', 'Lactic Acid', 'MAP Kinase Signaling System', 'Microscopy, Electron, Transmission', 'Nanopar... | 28,173,812 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['G03.787.151', 'G07.690.725.129'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', '... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Development of the anal vesicle, salivary glands and gut in the egg-larval parasitoid Chelonus inanitus: tools to take up nutrients and to manipulate the host? | Larvae of endoparasitoids undergo extensive morphological changes and often have special features to allow their development inside the host. We present the first detailed study on the development of the anal vesicle and the gut. The analyses reveal that the anal vesicle is first seen on the dorsal side of the abdomen ... | ['Anal Canal', 'Animals', 'Blotting, Western', 'Host-Parasite Interactions', 'Immunohistochemistry', 'Insect Proteins', 'Larva', 'Metamorphosis, Biological', 'Microscopy, Confocal', 'Microscopy, Electron, Scanning', 'Microscopy, Electron, Transmission', 'Salivary Glands', 'Spodoptera', 'Wasps'] | 16,386,270 | [['A03.556.124.526.070', 'A03.556.249.249.070'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G16.527.200.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Robust multi-scale superpixel classification for optic cup localization. | This paper presents an optimal model integration framework to robustly localize the optic cup in fundus images for glaucoma detection. This work is based on the existing superpixel classification approach and makes two major contributions. First, it addresses the issues of classification performance variations due to r... | ['Algorithms', 'Glaucoma', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Optic Disk', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Retinoscopy', 'Sensitivity and Specificity'] | 25,453,464 | [['G17.035', 'L01.224.050'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['L01.399.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The fabrication of a ceramic-metal crown to fit an existing removable partial denture clasp. | An indirect-direct technique of fabricating a ceramic-metal crown to fit a removable partial denture clasp has been described. The chief advantage of the technique is that the entire procedure can be performed without depriving the patient of the prosthesis. | ['Acrylic Resins', 'Crowns', 'Dental Abutments', 'Dental Porcelain', 'Dental Restoration, Temporary', 'Denture Design', 'Denture, Partial, Removable', 'Metals'] | 325,198 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['E06.780.346.250', 'E07.695.190.088'], ['E06.780.346.500', 'E07.695.190.175'], ['D25.339.376', 'J01.637.051.339.376', 'J01.637.153.377'], ['E06.323.528', 'E06.780.346.740', 'E07.695.190.192'], ['E06.780.346.760.300', 'E06.912.250'], ['E06.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Assessment of motor control using kinematics analysis in preschool children born very preterm. | The aim of this study was to better understand the mechanisms underlying the motor difficulties encountered by children born very preterm (VPT) without major sequelae from preterm birth. We compared the organization of visuo-manual aiming in preterm and full term (FT) preschool aged children based on performance and ki... | ['Biomechanical Phenomena', 'Child, Preschool', 'Developmental Disabilities', 'Feedback, Psychological', 'Humans', 'Infant', 'Infant, Extremely Low Birth Weight', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Kinesthesis', 'Motor Skills', 'Proprioception', 'Psychomotor Disorders', 'Reaction Time', 'Reference Value... | 17,455,240 | [['G01.154.090', 'G01.374.089'], ['M01.060.406.448'], ['F03.625.421'], ['F01.058.288', 'F04.754.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520.460.600.500'], ['M01.060.703.520'], ['C16.614.521'], ['F02.830.816.541.504', 'G11.561.790.541.587'], ['F02.808.260'], ['F02.830.816.5... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Directed modification of the structure of cytochrome P-450 substrates as a method of generating new inducers of the microsomal monooxygenase system]. | Using the previously obtained data on the substrate-type induction of monooxygenase by xenobiotics of phenobarbital type, the method of conversion of typical substrates for cytochrome P-450 into inducers of biosynthesis of this enzymatic system by blocking in the substrate molecule of the position subjected to oxidativ... | ['Animals', 'Chemical Phenomena', 'Chemistry', 'Cytochrome P-450 Enzyme System', 'Enzyme Induction', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Microsomes, Liver', 'Mixed Function Oxygenases', 'Oxidation-Reduction', 'Rats', 'Rats, Inbred Strains', 'Substrate Specificity'] | 3,663,765 | [['B01.050'], ['G02'], ['H01.181'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G05.308.320.200'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.284.835.540.541'], ['D08.811.682.690.708'], ['G02.700', 'G03.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Bradykinin and pituitary-adrenocortical function in the rabbit: in vitro and in vivo studies. | Bradykinin (BK) is a 9-amino acid peptide, which has been found to affect adrenocortical secretion in the calf and rat. We investigated the in vitro and in vivo effects of BK and its receptor antagonist [D-Arg, (Hyp3,D-Phe7)]-BK (BK-A) on pituitary-adrenocortical function in the rabbit. BK and BK-A raised basal release... | ['Adrenal Cortex', 'Adrenocorticotropic Hormone', 'Aldosterone', 'Animals', 'Bradykinin', 'Bradykinin Receptor Antagonists', 'Cells, Cultured', 'Corticosterone', 'Dose-Response Relationship, Drug', 'Male', 'Pituitary Gland', 'Rabbits', 'Receptors, Bradykinin', 'Time Factors'] | 10,382,676 | [['A06.300.071.140'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['B01.050'], ['D12.644.276.812.169', '... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of hypericum extract on the expression of serotonin receptors. | The influence of hypericum extract LI 160 on the expression of serotonin receptors was investigated using a neuroblastoma cell line to establish a model for the regulation of neurotransmitters by immunologically active compounds such as cytokines. The cells were incubated with hypericum extract LI 160 in kinetic form f... | ['Animals', 'Antidepressive Agents', 'Hypericum', 'Interleukin-1', 'Neuroblastoma', 'Perylene', 'Plant Extracts', 'Plants, Medicinal', 'Quercetin', 'Rats', 'Receptors, Serotonin', 'Serotonin Antagonists', 'Tumor Cells, Cultured', 'Xanthenes'] | 7,857,514 | [['B01.050'], ['D27.505.954.427.700.122'], ['B01.650.940.800.575.912.250.859.625.500'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ADP-ribosylation of thylakoid membrane polypeptides by cholera toxin is correlated with inhibition of thylakoid GTPase activity and protein phosphorylation. | Incubation of pea thylakoid membranes with [32P]-NAD+ in the presence of cholera toxin resulted in the [32P]-ADP-ribosylation of a 60 kDa thylakoid membrane polypeptide. When ATP was included in the incubation mixture, a 29 kDa polypeptide was also labelled. In the absence of electron transfer cofactors or inhibitors, ... | ['Adenosine Diphosphate Ribose', 'Adenosine Triphosphate', 'Chloroplasts', 'Cholera Toxin', 'Fabaceae', 'GTP Phosphohydrolases', 'GTP-Binding Proteins', 'Light', 'Membrane Proteins', 'NAD', 'Phosphoric Monoester Hydrolases', 'Phosphorylation', 'Phosphotransferases', 'Plant Proteins', 'Plants, Medicinal'] | 2,561,911 | [['D03.633.100.759.646.138.124.070.125', 'D09.408.620.569.070.125', 'D13.695.667.138.124.070.125', 'D13.695.827.068.124.070.125', 'D13.695.827.708.070.125'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.284.430.214.190.875.700.140'], ['D08.811.913.400.725.115.180', 'D23.946.123.1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial. | BACKGROUND: Primary percutaneous coronary intervention (PCI) is the most common method of reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) in the United States. The intersection between processes of care and performance measures such as door-to-balloon (D2B) times and clinical trials eval... | ['Aged', 'Blood Pressure', 'Coronary Angiography', 'Coronary Circulation', 'Electrocardiography', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardial Reperfusion', 'Percutaneous Coronary Intervention', 'Prospective Studies'] | 25,488,040 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['G09.330.100.324'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner? | Tissue and organ rejuvenation and senescence/aging are closely related to the function of stem cells. Recently, we demonstrated that a population of pluripotent Oct-4+ SSEA-1+Sca-1+Lin-CD45- very small embryonic-like stem cells (VSELs) resides in the adult murine bone marrow (BM) and other murine tissues. We hypothesiz... | ['Adult', 'Aging', 'Animals', 'Cellular Senescence', 'Embryonic Stem Cells', 'Genomic Imprinting', 'Humans', 'Insulin-Like Growth Factor I', 'Mice', 'Pluripotent Stem Cells', 'Regeneration', 'Stem Cell Niche'] | 21,084,728 | [['M01.060.116'], ['G07.345.124'], ['B01.050'], ['G04.043'], ['A11.872.700.250'], ['G05.308.203.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.872.700'], ['G16.762'], ['G... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Breaking the matching in nested case-control data offered several advantages for risk estimation. | OBJECTIVE: To demonstrate the advantage of using weighted Cox regression to analyze nested case-control data in overcoming limitations encountered with traditional conditional logistic regression.STUDY DESIGN AND SETTING: We analyzed data from 1,051 women who were sampled in a case-control study of lung cancer nested w... | ['Aged', 'Breast Neoplasms', 'Case-Control Studies', 'Causality', 'Comorbidity', 'Female', 'Humans', 'Logistic Models', 'Lung Neoplasms', 'Middle Aged', 'Proportional Hazards Models', 'Risk', 'Risk Factors', 'Smoking', 'Sweden'] | 27,923,734 | [['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N05.715.350.200', 'N06.850.490.625'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Further studies on the genetic control of murine corneal response to Pseudomonas aeruginosa. | Intracorneal challenge of mouse strains DBA/1 and DBA/2 with Pseudomonas aeruginosa demonstrated that these strains were naturally resistant; they spontaneously recovered within four weeks postinfection. On the other hand, mouse strains BALB/c and C57BL/6 were susceptible to corneal infections and exhibited permanent e... | ['Animals', 'Female', 'Genes, Dominant', 'Hybridization, Genetic', 'Immunity, Innate', 'Immunogenetics', 'Keratitis', 'Mice', 'Mice, Inbred Strains', 'Pseudomonas Infections', 'Species Specificity'] | 6,658,287 | [['B01.050'], ['G05.360.340.024.340.240', 'G05.420.320'], ['E05.820.150.390', 'G05.090.390'], ['G12.450.564'], ['H01.158.273.343.420'], ['C11.204.564'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['C01.150.252.400.739'], ['G16.824']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Imidazo[5,1-f]triazin-4(3H)-ones, a new class of potent PDE 5 inhibitors. | 2-aryl-substituted imidazo[5,1-f][1,2,4]triazin-4(3H)-ones represent a new class of potent cGMP-PDE 5 inhibitors that prove to be superior to other purine-isosteric inhibitors. Subnanomolar inhibitors of PDE 5 with activity in in vivo models for erectile dysfunction have been identified. BAY 38-9456 (Vardenafil-hydroch... | ["3',5'-Cyclic-GMP Phosphodiesterases", 'Animals', 'Cyclic Nucleotide Phosphodiesterases, Type 5', 'Enzyme Inhibitors', 'Erectile Dysfunction', 'Imidazoles', 'Inhibitory Concentration 50', 'Male', 'Protein Binding', 'Rabbits', 'Structure-Activity Relationship', 'Triazines'] | 11,958,981 | [['D08.811.277.352.640.155', 'D12.644.360.009', 'D12.776.476.009'], ['B01.050'], ['D08.811.277.352.640.150.500', 'D08.811.277.352.640.155.500', 'D12.644.360.008.500', 'D12.644.360.009.500', 'D12.776.476.008.500', 'D12.776.476.009.500'], ['D27.505.519.389'], ['C12.294.644.486', 'F03.835.400'], ['D03.383.129.308'], ['E05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type. | An 80,000 base-pair region from the gene locus encoding the variable regions of the human immunoglobulins of the kappa type (V kappa genes) was cloned and analysed. The region comprises five V kappa sequences of subgroup I and one interspersed V kappa pseudogene of subgroup II. The six genes and pseudogenes are arrange... | ['Amino Acid Sequence', 'Antibody Diversity', 'Base Composition', 'Base Sequence', 'Biological Evolution', 'Chromosome Mapping', 'DNA Restriction Enzymes', 'Gene Amplification', 'Genes', 'Humans', 'Immunoglobulin Light Chains', 'Immunoglobulin Variable Region', 'Immunoglobulin kappa-Chains'] | 6,086,934 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G05.365.036', 'G12.500.199'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['E05.393.183'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['G05.308.250', 'G05.365.590.310', 'G05.558... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The relationship between non-symbolic multiplication and division in childhood. | Children without formal education in addition and subtraction are able to perform multi-step operations over an approximate number of objects. Further, their performance improves when solving approximate (but not exact) addition and subtraction problems that allow for inversion as a shortcut (e.g., a + b - b = a). The ... | ['Child', 'Concept Formation', 'Female', 'Humans', 'Learning', 'Male', 'Mathematics', 'Photic Stimulation', 'Problem Solving', 'Social Class'] | 26,880,261 | [['M01.060.406'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['H01.548'], ['E05.723.729'], ['F02.463.425.725', 'F02.463.785.810'], ['I01.880.853.996.755', 'N01.824.782']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Selective modulation of collagenase 1 gene expression by the chemotherapeutic agent doxorubicin. | Matrix metalloproteinases (MMPs) play a crucial role in tumor cell invasion and metastasis due to their ability to digest basement membrane and extracellular matrix components, thereby facilitating cell movement through connective tissues. At noncytotoxic concentrations, i.e., concentrations lower than those normally u... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Antineoplastic Agents', 'Cell Division', 'Collagen', 'Collagenases', 'Doxorubicin', 'Gelatinases', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Matrix Metalloproteinase 1', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 9', 'Melanoma', 'Metal... | 9,918,220 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D27.505.954.248'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D05.750.07... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High prevalence of screen detected prostate cancer in West Africans: implications for racial disparity of prostate cancer. | PURPOSE: To our knowledge the reasons for the high rates of prostate cancer in black American men are unknown. Genetic and lifestyle factors have been implicated. Better understanding of prostate cancer rates in West African men would help clarify why black American men have such high rates since the groups share genet... | ['African Americans', 'African Continental Ancestry Group', 'Aged', 'Ghana', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Prostate-Specific Antigen', 'Prostatic Neoplasms'] | 24,747,091 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['M01.060.116.100'], ['Z01.058.290.190.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['D08.811.277.656.300.76... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Dual-band perfect absorber for multispectral plasmon-enhanced infrared spectroscopy. | Metamaterial-based perfect absorbers utilize intrinsic loss, with the aid of appropriate structural design, to achieve near unity absorption at a certain wavelength. For most of the reported absorbers, the absorption occurs only at a single wavelength where plasmon resonances are excited in the nanostructures. Here we ... | ['Absorption', 'Equipment Design', 'Equipment Failure Analysis', 'Gold', 'Light', 'Metal Nanoparticles', 'Scattering, Radiation', 'Spectrophotometry, Infrared', 'Surface Plasmon Resonance'] | 22,920,565 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['E05.320'], ['E05.325.192'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['J01.637.512.600.500'], ['E05.196.822', 'G01.867'], ['E05.196.712.726.676', 'E05.1... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Role of the actin Ala-108-Pro-112 loop in actin polymerization and ATPase activities. | Actin plays fundamental roles in a variety of cell functions in eukaryotic cells. The polymerization-depolymerization cycle, between monomeric G-actin and fibrous F-actin, drives essential cell processes. Recently, we proposed the atomic model for the F-actin structure and found that actin was in the twisted form in th... | ['Actins', 'Adenosine Triphosphatases', 'Amino Acid Substitution', 'Animals', 'Avian Proteins', 'Chickens', 'Humans', 'Multienzyme Complexes', 'Mutation, Missense', 'Protein Structure, Secondary', 'Protein Structure, Tertiary'] | 23,135,274 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D08.811.277.040.025'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D12.776.095'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.500.562', 'D08.811.600'], ['G05.36... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The stability of mechanical calibration for a kV cone beam computed tomography system integrated with linear accelerator. | The geometric accuracy and precision of an image-guided treatment system were assessed. Image guidance is performed using an x-ray volume imaging (XVI) system integrated with a linear accelerator and treatment planning system. Using an amorphous silicon detector and x-ray tube, volumetric computed tomography images are... | ['Calibration', 'Equipment Design', 'Equipment Failure Analysis', 'Particle Accelerators', 'Phantoms, Imaging', 'Quality Assurance, Health Care', 'Radiometry', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Computer-Assisted', 'Reproducibility of Results', 'Sensitivity and Specificity... | 16,485,420 | [['E05.978.155'], ['E05.320'], ['E05.325.192'], ['E07.710.680'], ['E07.671'], ['N04.761.700', 'N05.700'], ['E05.799'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E02.815.635', 'L01.313.500.750.100.710.600'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Gastric surgery is not a risk for Barrett's esophagus or esophageal adenocarcinoma. | BACKGROUND & AIMS: The contribution of duodeno-gastroesophageal reflux to the development of Barrett's esophagus has remained an interesting but controversial topic. The present study assessed the risk for Barrett's esophagus after partial gastrectomy.METHODS: The data of outpatients from a medicine and gastroenterolog... | ['Adenocarcinoma', 'Aged', 'Barrett Esophagus', 'Esophageal Neoplasms', 'Female', 'Gastrectomy', 'Humans', 'Male', 'Middle Aged', 'Odds Ratio', 'Risk Factors'] | 11,729,106 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.834.154', 'C06.405.117.102'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.3... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An in vitro evaluation of gaseous microemboli handling by contemporary venous reservoirs and oxygenator systems using EDAC. | Gaseous microemboli (GME) generated during cardiopulmonary bypass (CPB) can present a significant risk to patient outcomes, specifically if they are delivered to the cerebral vasculature. A number of GME sources have been identified, leading to improved clinical practice and equipment design to ameliorate the presence ... | ['Cardiopulmonary Bypass', 'Embolic Protection Devices', 'Embolism, Air', 'Extracorporeal Membrane Oxygenation', 'Humans'] | 25,987,549 | [['E04.292.413'], ['E07.695.207'], ['C14.907.355.350.254'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optic Disc Pit Maculopathy: New Perspectives on the Natural History. | PURPOSE: To investigate the natural history of optic disc pit maculopathy and explore the associations between demographic, anatomic, and functional characteristics.DESIGN: Retrospective, comparative case series.METHODS: This was a single-center medical record review of previously untreated optic disc pit maculopathy. ... | ['Adult', 'Female', 'Follow-Up Studies', 'Humans', 'Macula Lutea', 'Macular Degeneration', 'Male', 'Optic Disk', 'Optic Nerve Diseases', 'Prognosis', 'Retrospective Studies', 'Tomography, Optical Coherence', 'Visual Acuity'] | 31,095,956 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.729.522'], ['C11.768.585.439'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['C10.292.700', 'C11.640'], ['E01.789'], ['E05.318.372.500.500.500', 'E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mechanism of interaction between Ku protein and DNA. | The mechanism of interaction between the Ku autoantigenic protein, a heterodimer of noncovalently linked 70,000- and 80,000-dalton subunits, and DNA was studied using immunoaffinity-purified Ku protein and a 300-base pair EcoRI fragment from HeLa cell DNA. In the nitrocellulose filter-binding assay, the Ku protein boun... | ['Antigens, Nuclear', 'Antigens, Surface', 'Autoantigens', 'Binding, Competitive', 'DNA', 'DNA Helicases', 'DNA Restriction Enzymes', 'DNA-Binding Proteins', 'Humans', 'Immunoglobulin G', 'Immunologic Techniques', 'Ku Autoantigen', 'Macromolecular Substances', 'Myositis', 'Nucleic Acid Denaturation', 'Osmolar Concentra... | 3,015,926 | [['D12.776.660.625', 'D23.050.290'], ['D23.050.301'], ['D23.050.422'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D13.444.308'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D12.776.260'], ['B01.050.150.900.649.313.988... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Surgical management of bilateral ureteral endometriosis. | Ureteral endometriosis is a rare disease that typically is unilateral. Endometriosis involving both ureters and surgical management after hormone therapy failure has seldom been described. We describe a patient with bilateral ureteral endometriosis who underwent ureteroneocystostomy with psoas hitches of both ureters. ... | ['Adult', 'Endometriosis', 'Female', 'Humans', 'Ureteral Diseases'] | 17,115,290 | [['M01.060.116'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.725', 'C13.351.968.725']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Vertebral trabecular bone in various age groups and in osteoporosis-- morphometry and bone matrix biochemistry]. | Vertebral trabecular bone was analysed by morphometry and bone matrix biochemistry. Trabecular bone volume (TBV) and mean trabecular plate thickness (MTPT) decreased with age. TBV was significantly correlated with MTPT and mean trabecular plate density (MTPD). The individual structure of trabecular bone could be descri... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Autopsy', 'Bone Development', 'Collagen', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteoporosis', 'Reference Values', 'Spine'] | 1,708,593 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.116.198.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Interpersonal and social rhythm group therapy for patients with bipolar disorder. | This article describes Interpersonal and Social Rhythm Therapy (IPSRT) adapted for use in a group setting for patients with bipolar disorder. In a preliminary efficacy study, we studied the pre-post group treatment effect on affective symptoms. One-year pre-post findings in the IPSRT group indicated that this modality ... | ['Adult', 'Bipolar Disorder', 'Circadian Rhythm', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Psychotherapy, Group', 'Secondary Prevention', 'Treatment Outcome'] | 23,252,817 | [['M01.060.116'], ['F03.084.500'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['F04.711.513.653'], ['F04.711.780'], ['F04.754.864.581'], ['E02.897', 'N02.421.726.825', 'N06.850.780.750'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Distinct Pattern of Thymidine Analogue Mutations with K65R in Patients Failing Tenofovir-Based Antiretroviral Therapy. | Historically, in HIV patients, the K65R mutation and thymidine analogue mutations (TAMs) have been reported to rarely coexist. We retrospectively reviewed genotype data from paired samples in a cohort of HIV-1-infected Nigerian patients failing first-line antiretroviral therapies containing zidovudine (AZT) or tenofovi... | ['Drug Resistance, Viral', 'HIV Infections', 'HIV Reverse Transcriptase', 'HIV-1', 'Humans', 'Nigeria', 'Retrospective Studies', 'Reverse Transcriptase Inhibitors', 'Tenofovir', 'Treatment Failure', 'Viral Load', 'Zidovudine'] | 29,084,434 | [['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['D08.811.913.696.445.308.300.750.187', 'D12.776.964.775.375.545.875', 'D12.776.964.775.375.750.187', 'D12.776.964.775.562.764.875', 'D1... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Granzyme B and TIA-1 expression in chronic and acute on chronic renal allograft rejection. | Although active inflammation may be deleterious and indicate immunologic activation in chronically rejected grafts, the underlying mechanism of tissue destruction has been little studied. Twenty-four cases of chronic rejection (CR) with or without acute rejection (AR) were stained with antibodies against CD3, CD8, CD68... | ['Adult', 'CD3 Complex', 'CD8 Antigens', 'Female', 'Follow-Up Studies', 'Graft Rejection', 'Granzymes', 'Humans', 'Immunohistochemistry', 'Kidney Transplantation', 'Male', 'Membrane Proteins', 'Poly(A)-Binding Proteins', 'Proteins', 'RNA-Binding Proteins', 'Serine Endopeptidases', 'T-Cell Intracellular Antigen-1', 'Tra... | 11,456,393 | [['M01.060.116'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['D23.050.301.264.894.108', 'D23.101.100.894.108'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.328'], ['D08.811.277.656.300.760.397', 'D08.811.277.656.959.350.397'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Determination of conformer-specific partition coefficients in octanol/water systems. | The first conformer-specific experimental partition coefficients are presented for octanol/water, the most widespread solvent system to predict lipophilicity of drugs. Rotamer populations in octanol and water were elucidated from 1H NMR vicinal coupling constants and were combined with classical partition coefficients ... | ['Algorithms', 'Amphetamine', 'Clenbuterol', 'Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Octanols', 'Pharmaceutical Preparations', 'Solubility', 'Water'] | 12,747,795 | [['G17.035', 'L01.224.050'], ['D02.092.471.683.152.110'], ['D02.033.100.291.231', 'D02.092.063.291.231'], ['E05.196.867.519'], ['G02.111.570.820'], ['D02.033.415.600', 'D10.289.600'], ['D26'], ['G02.805'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Squaraine Dyes: Interaction with Bovine Serum Albumin to Investigate Supramolecular Adducts with Aggregation-Induced Emission (AIE) Properties. | Bovine serum albumin (BSA)-squaraine supramolecular adducts with aggregation-induced emission (AIE) properties were prepared and characterized by spectroscopic methods. While squaraine dyes showed a very low fluorescence quantum yield in water, a great enhancement in the fluorescence of the aggregated BSA adducts was a... | ['Animals', 'Cattle', 'Cyclobutanes', 'Fluorescent Dyes', 'Kinetics', 'Microscopy, Electron, Transmission', 'Phenols', 'Serum Albumin, Bovine', 'Spectrometry, Fluorescence', 'Thermodynamics'] | 30,645,031 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D02.455.426.392.368.201'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['D02.455.426.559.389.657'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['E05.196.712.516.600.676', 'E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The correlation of changes in systolic blood pressure with regional anatomical regression of hypertensive left ventricular hypertrophy in patients on chronic antihypertensive therapy (greater than 1 year): alpha-methyldopa compared to propranolol. | Twenty patients with mild to moderate hypertension and evidence of left ventricular hypertrophy (relative wall thickness greater than or equal to 0.45), who previously had not received either alpha-methyldopa or propranolol, were allocated at random to treatment with one or other of these drugs as monotherapy after a 2... | ['Adult', 'Blood Pressure', 'Cardiomegaly', 'Echocardiography', 'Female', 'Heart Rate', 'Humans', 'Hypertension', 'Male', 'Methyldopa', 'Middle Aged', 'Myocardium', 'Propranolol'] | 6,233,093 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.195', 'C23.300.775.250'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D02.092.311.200.538', 'D02.455.426.559.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Formation of ubiquitin dimers via azide-alkyne click reaction. | The conjugation of poly-ubiquitin chains is a widespread post-translational modification of proteins that plays a role in many different cellular processes. Notably, the biological function of the attached ubiquitin chain depends on which lysine residue is used for chain formation. Here, we report a method for the modu... | ['Alkynes', 'Amino Acids', 'Azides', 'Click Chemistry', 'Methanosarcina barkeri', 'Polyubiquitin', 'Protein Processing, Post-Translational', 'RNA, Transfer', 'Ubiquitination'] | 22,350,914 | [['D02.455.326.397'], ['D12.125'], ['D01.625.100', 'D02.159'], ['E05.197.124', 'J01.897.836.249.124'], ['B02.200.765.550.550.200'], ['D12.776.947.500.500'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', 'G05.308.670.600'], ['D13.444.735.757'], ['G02.111.660.871.790.600.925', 'G02.111.691.600.775... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Organization of rhythmic buccal motor output of Lymnaea stagnalis in the absence of food. | The pond snail Lymnaea stagnalis exhibits spontaneous rasping movements in the absence of food which are thought to be involved in food searching activity. Rasping activity is patterned into bouts, separated by periods of quiescence. Recordings from buccal feeding motoneurons in the isolated CNS reveal similar bouts of... | ['Animals', 'Appetitive Behavior', 'Central Nervous System', 'Feeding Behavior', 'Hunger', 'Interneurons', 'Lymnaea', 'Masticatory Muscles', 'Motor Neurons', 'Nerve Net'] | 3,689,287 | [['B01.050'], ['F01.145.113.111'], ['A08.186'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.658.293.391', 'G07.203.650.390', 'G10.261.390'], ['A08.675.358', 'A11.671.358'], ['B01.050.500.644.400.750.645'], ['A02.633.567.600', 'A14.530'], ['A08.675.655.500', 'A11.671.655.500'], ['A08.511']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Health Locus of Control Beliefs in Health Care Providers in the Pacific Basin. | As part of the strategic plan to improve preconception care, health care providers are advised to counsel women about developing a reproductive life plan. Women are asked think about whether they want to become pregnant and have children and if so, when they would like to do so. The utility of a reproductive life plan ... | ['Adult', 'Attitude of Health Personnel', 'Cross-Sectional Studies', 'Female', 'Health Personnel', 'Humans', 'Male', 'Micronesia', 'Middle Aged', 'Preconception Care', 'Social Control, Formal', 'Surveys and Questionnaires'] | 30,533,285 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.680'], ['M01.060.116.630'], ['E02.760.775', 'N02.421.143.620.620', 'N02.421.585.775', 'N02.421.920.6... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of hydroxamic acids on growth and urease activity in Corynebacterium renale. | Studies were conducted on the effect of four different hydroxamic acids (HA), hydroxyurea, acetohydroxamic acid, p-flurobenzoylhydroxamic acid and sorbylhydroxamic acid, on the growth and urease activity of Corynebacterium renale. The addition of each of these HA, at concentrations ranging form 10(-3) to 10(-5) M, to m... | ['Cell-Free System', 'Chemical Phenomena', 'Chemistry', 'Corynebacterium', 'Hydroxamic Acids', 'Hydroxyurea', 'Urease'] | 1,260,545 | [['A11.284.835.168'], ['G02'], ['H01.181'], ['B03.510.024.250', 'B03.510.460.400.400.200'], ['D02.092.570.394', 'D02.241.511.372'], ['D02.065.950.395'], ['D08.811.277.087.902']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Whole body oxygen uptake is not a good indicator of liver allograft function following orthotopic liver transplantation. | Variations of whole body oxygen uptake (VO2) have been studied during orthotopic liver transplantation. Some authors have suggested that the increase in VO2 after revascularization of the graft could be an index of good function of the grafted liver and thus low VO2 an early sign of primary non-function. The purpose of... | ['Adolescent', 'Adult', 'Anesthesia, Intravenous', 'Aspartate Aminotransferases', 'Constriction', 'Factor V', 'Hepatectomy', 'Humans', 'Liver Transplantation', 'Middle Aged', 'Organ Size', 'Oxygen Consumption', 'Portacaval Shunt, Surgical', 'Portal Vein', 'Prothrombin', 'Time Factors', 'Transplantation, Homologous', 'V... | 8,050,425 | [['M01.060.057'], ['M01.060.116'], ['E03.155.308'], ['D08.811.913.477.700.225'], ['E05.225'], ['D12.776.124.125.300', 'D12.776.811.272', 'D23.119.300'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Investigation of the diversity of homoacetogenic bacteria in mesophilic and thermophilic anaerobic sludges using the formyltetrahydrofolate synthetase gene. | Homoacetogenic bacteria are strict anaerobes capable of autotrophic growth on H(2)/CO(2) or CO, and of heterotrophic growth on a wide range of sugars, alcohols, methoxylated aromatic compounds and one carbon compounds, yielding acetate as their sole metabolic end-product. Batch activity tests on anaerobic granular slud... | ['Alkanesulfonic Acids', 'Anaerobiosis', 'Bacteria', 'Bacterial Proteins', 'Formate-Tetrahydrofolate Ligase', 'Formates', 'Phylogeny', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Sewage', 'Substrate Specificity', 'Temperature'] | 18,401,137 | [['D02.455.326.146.100', 'D02.886.645.600.055'], ['G02.111.062', 'G03.078'], ['B03'], ['D12.776.097'], ['D08.811.464.259.550'], ['D02.241.081.420'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.620.500'], ['G05.365.795.595'], ['D20.944.932.500'], ['G02.111.835'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Disinfection of greywater effluent and regrowth potential of selected bacteria. | Chlorination and UV irradiation of RBC (rotating biological contactor)-treated light GW (greywater) was investigated. The ability of chlorine and UV to inactivate indictor bacteria (FC - Faecal Coliforms, HPC - Heterotrophic Plate Count) and specific pathogens (P.a. - Pseudomonas aeruginosa sp., S.a. - Staphylococcus a... | ['Bacteria', 'Biodegradation, Environmental', 'Chlorine', 'Disinfection', 'Halogenation', 'Pilot Projects', 'Ultraviolet Rays', 'Waste Disposal, Fluid', 'Water Microbiology'] | 21,411,943 | [['B03'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.268.380.150', 'D01.362.225'], ['N06.850.780.200.450.850.375'], ['G02.111.323', 'G03.360'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.... | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of alloxan induced mild insulin dependent diabetes mellitus on rat erythrocyte cytosolic dehydrogenases. | In order to understand how the red cell of mild insulin dependent diabetes mellitus rat perform the normal physiological function and maintain integrity cytosolic dehydrogenases were assayed. Lactate dehydrogenase produces the cofactor for glycolytic enzymes while glucose 6-phosphate dehydrogenase and 6-phosphogluconat... | ['Animals', 'Cytosol', 'Diabetes Mellitus, Experimental', 'Erythrocytes', 'Glucosephosphate Dehydrogenase', 'L-Lactate Dehydrogenase', 'Phosphogluconate Dehydrogenase', 'Rats'] | 8,781,036 | [['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D08.811.682.047.150.300'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['D08.811.682.047.150.600'], ['B01.050.1... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Facile synthesis of stable CdTe/CdS QDs using dithiol as surface ligand for alkaline phosphatase detection based on inner filter effect. | Alkaline phosphatase (ALP) is a universal and important hydrolase that has been proved to be associated with several diseases. Herein, a simple and effective method was proposed for ALP detection based on the inner filter effect of p-nitrophenol (pNP) on the fluorescence of CdTe/CdS quantum dots (QDs). For the preparat... | ['Alkaline Phosphatase', 'Cadmium Compounds', 'Energy Transfer', 'Fluorescence', 'Fluorescent Dyes', 'Humans', 'Limit of Detection', 'Nitrophenols', 'Organophosphorus Compounds', 'Quantum Dots', 'Spectrometry, Fluorescence', 'Sulfides', 'Tellurium'] | 30,567,651 | [['D08.811.277.352.650.035'], ['D01.142'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. | Neuronal activity causes local changes in cerebral blood flow, blood volume, and blood oxygenation. Magnetic resonance imaging (MRI) techniques sensitive to changes in cerebral blood flow and blood oxygenation were developed by high-speed echo planar imaging. These techniques were used to obtain completely noninvasive ... | ['Animals', 'Brain', 'Cerebrovascular Circulation', 'Functional Laterality', 'Humans', 'Magnetic Resonance Imaging', 'Magnetic Resonance Spectroscopy', 'Mathematics', 'Models, Theoretical', 'Oxygen', 'Photic Stimulation', 'Physical Stimulation', 'Rabbits', 'Time Factors', 'Touch', 'Visual Cortex'] | 1,608,978 | [['B01.050'], ['A08.186.211'], ['G09.330.100.159'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E05.196.867.519'], ['H01.548'], ['E05.599'], ['D01.268.185.550', 'D01.362.670'], ['E05.723.729'], ['E05.723'], ['B01.050.150.900.649.313.968.700'], ['G0... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Semen cryopreservation for the creation of a Spanish poultry breeds cryobank: optimization of freezing rate and equilibration time. | A sperm cryopreservation protocol requiring dimethylacetamide (DMA, 6%) as a cryoprotectant was optimized via assays involving different prefreezing equilibration times (1, 10, 30, 60, and 120 min at 5°C) and different freezing rates achieved by the following: 1) using nitrogen vapor to reduce the temperature from 5°C ... | ['Animals', 'Chickens', 'Cryopreservation', 'Female', 'Fertilization', 'Male', 'Semen Preservation', 'Spain', 'Spermatozoa', 'Time Factors'] | 21,844,272 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['G08.686.784.277'], ['E02.792.833.890', 'E05.760.833.890'], ['Z01.542.846'], ['A05.360.490.89... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Emerging fluoroquinolone resistance in Streptococcus agalactiae in South Korea. | The goal of this study was to determine the prevalence of fluoroquinolone resistance in Streptococcus agalactiae and the serotype distribution of this resistant bacterium. S. agalactiae strains collected from 221 asymptomatic pregnant women (35-37 weeks of gestation) and 838 patients with S. agalactiae infection in Kor... | ['Anti-Bacterial Agents', 'Carrier State', 'Drug Resistance, Bacterial', 'Female', 'Fluoroquinolones', 'Humans', 'Microbial Sensitivity Tests', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Republic of Korea', 'Serotyping', 'Streptococcal Infections', 'Streptococcus agalactiae'] | 22,752,224 | [['D27.505.954.122.085'], ['N06.850.520.169'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['D03.633.100.810.835.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['Z01.252.474.557.750'],... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Role of substrate in imparting calcium and phospholipid requirements to protein kinase C activation. | The role of substrate in influencing the cofactor requirements of the phospholipid- and Ca2+-dependent protein kinase C (PKC) was investigated by using several substrates. All of the substrates tested, including histone, troponin I, myosin light chain, protamine, poly(arginine, serine) (PAS), poly(lysine, serine) (PLS)... | ['Animals', 'Brain', 'Calcium', 'Cattle', 'Energy Transfer', 'Enzyme Activation', 'Kinetics', 'Osmolar Concentration', 'Peptides', 'Phospholipids', 'Polylysine', 'Protein Kinase C', 'Spectrometry, Fluorescence'] | 3,593,703 | [['B01.050'], ['A08.186.211'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['G02.111.263', 'G03.328'], ['G01.374.661', 'G02.111.490'], ['G02.640'], ['D12.644'], ['D10.570.755'], ['D12.125.068.555.750', 'D12.125.095.647.750', ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Supercritical fluid assisted process for the generation of cellulose acetate loaded structures, potentially useful for tissue engineering applications. | Supercritical CO2 phase inversion offers an alternative to obtain solvent free structures with short processing times and preservation of the morphology. We prepared cellulose acetate structures loaded with drug (ibuprofen) to perform experiments at pressures and temperatures ranging between 150 and 250 bars and 35 and... | ['Cellulose', 'Delayed-Action Preparations', 'Ibuprofen', 'Nanofibers', 'Tissue Engineering'] | 26,652,399 | [['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D26.255.210', 'E02.319.300.253'], ['D02.241.223.701.430'], ['J01.637.512.300'], ['E05.481.500.311.500', 'J01.293.069.249.500']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Safe drinking water and clean air: an experimental study evaluating the concept of combining household water treatment and indoor air improvement using the Water Disinfection Stove (WADIS). | Indoor air pollution and unsafe water remain two of the most important environmental risk factors for the global burden of infectious diseases. Improved stoves and household water treatment (HWT) methods represent two of the most effective interventions to fight respiratory and diarrhoeal illnesses at household level. ... | ['Adult', 'Air Pollution, Indoor', 'Attitude', 'Bolivia', 'Disinfection', 'Female', 'Household Articles', 'Humans', 'Male', 'Pilot Projects', 'Socioeconomic Factors', 'Water', 'Water Purification', 'Water Supply'] | 19,230,761 | [['M01.060.116'], ['N06.850.460.100.080'], ['F01.100'], ['Z01.107.757.136'], ['N06.850.780.200.450.850.375'], ['J01.494'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['I01.880.853.996', 'N01.824'], ['D01.045.250.875', 'D01.248.497.1... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Molecular markers of cartilage breakdown and synovitis at baseline as predictors of structural progression of hip osteoarthritis. The ECHODIAH Cohort. | OBJECTIVE: To determine whether systemic markers of bone, cartilage, and synovium can predict structural progression of osteoarthritis (OA).METHODS: Patients with painful hip OA were treated with diacerein or placebo in a multicentre, prospective, double blind, 3 year follow up trial. The following information was coll... | ['Aged', 'Arthroplasty, Replacement, Hip', 'Biomarkers', 'Cartilage, Articular', 'Collagen', 'Disease Progression', 'Female', 'Humans', 'Hyaluronic Acid', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Osteoarthritis, Hip', 'Prognosis', 'Prospective Studies', 'Radiography', 'Severity of Illness Index', 'Synovitis'] | 16,322,084 | [['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D23.101'], ['A02.165.407.150', 'A02.835.583.192'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['E05.318.372.500.750.500', 'N05.715.360.33... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of 645 MeV and 9.2 GeV protons on Artemia eggs. | Developmental capacities of Artemia eggs have been studied after exposure to 645 MeV or 9.2 GeV protons. Effects of proton irradiation were studied in comparison with 60Co gamma ray irradiation, endpoints being emergence, hatching and 4-5 day old live nauplii percentages. Effectiveness of 645 MeV protons is greater tha... | ['Animals', 'Artemia', 'Dose-Response Relationship, Radiation', 'Female', 'Gamma Rays', 'Male', 'Ovum', 'Protons', 'Relative Biological Effectiveness', 'Time Factors'] | 232,497 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors associated with home advantage in English and Scottish soccer matches. | Using the results from the end-of-season (1992-93) league tables, overall home advantage was confirmed in the eight major divisions of the English and Scottish football leagues. The degree of home advantage was found to vary significantly across the divisions. Furthermore, these divisional differences in home advantage... | ['England', 'Humans', 'Scotland', 'Soccer'] | 8,737,326 | [['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.363.766'], ['I03.450.642.845.800']] | ['Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Direct continuities between cisternae at different levels of the Golgi complex in glucose-stimulated mouse islet beta cells. | Direct continuity between the membranes of cisternae in the Golgi complex in mammalian cells rarely has been observed; when seen, its documentation has been equivocal. Here we have used dual-axis electron microscope tomography to examine the architecture of the Golgi in three dimensions at approximately 6-nm resolution... | ['Animals', 'Cryoelectron Microscopy', 'Female', 'Freeze Substitution', 'Glucose', 'Golgi Apparatus', 'Islets of Langerhans', 'Mice', 'Mice, Inbred BALB C'] | 15,064,406 | [['B01.050'], ['E01.370.350.515.402.150', 'E05.595.402.150'], ['E01.370.225.500.620.760.160.260.270', 'E01.370.225.750.600.760.160.260.270', 'E02.792.156.260.270', 'E05.200.500.620.760.160.260.270', 'E05.200.750.600.760.160.260.270', 'E05.760.156.260.270'], ['D09.947.875.359.448'], ['A11.284.430.214.190.875.336'], ['A0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis of an association of TNF -308G>A polymorphism with a risk for pulmonary sarcoidosis in the Russian population of the Republic of Karelia]. | AIM: To analyze an association of TNF -308G>A polymorphism with a risk for pulmonary sarcoidosis (PS) in the Russian population of the Republic of Kareli.SUBJECTS AND METHODS: 84 patients with persistent PS and 96 donors without clinical manifestations of this disease (a control group) were examined. Polymerase chain r... | ['Adult', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Polymorphism, Single Nucleotide', 'Risk Assessment', 'Russia', 'Sarcoidosis, Pulmonary', 'Tumor Necrosis Factor-alpha'] | 28,378,732 | [['M01.060.116'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.598'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['Z01.252.122.500', 'Z01.542.248.775'], ['C08.381.483.725', 'C1... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Assessment of a knowledge-acquisition tool for writing Medical Logic Modules in the Arden Syntax. | We have created a tool that allows users unfamiliar with the Arden Syntax and our underlying database to create Medical Logic Modules (MLMs). In a study of this tool (N 16), subjects found it easy to use (mean score - 4.69 on a scale of 1-5, 5 being best). Each subject created 3 MLMs of varying complexity following a p... | ['Artificial Intelligence', 'Decision Support Techniques', 'Programming Languages', 'Software Design', 'User-Computer Interface'] | 8,947,730 | [['G17.035.250', 'L01.224.050.375'], ['E05.245', 'L01.313.500.750.190'], ['L01.224.900.780'], ['L01.224.900.820'], ['L01.224.900.910']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Site-targeted mutagenesis for stabilization of recombinant monoclonal antibody expressed in tobacco (Nicotiana tabacum) plants. | This study examined the degradation pattern of a murine IgG1ê monoclonal antibody expressed in and extracted from transformedNicotiana tabacum Gel electrophoresis of leaf extracts revealed a consistent pattern of recombinant immunoglobulin bands, including intact and full-length antibody, as well as smaller antibody fr... | ['Animals', 'Antibodies, Monoclonal', 'Binding Sites', 'Blotting, Western', 'Mice', 'Mutagenesis, Site-Directed', 'Mutation', 'Peptide Hydrolases', 'Plant Leaves', 'Plants, Genetically Modified', 'Recombinant Proteins', 'Sequence Analysis, Protein', 'Tobacco'] | 26,712,217 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.120'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.420.601.575'], ['G05.365.590'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adolescent lipoprotein classifications according to National Health and Nutrition Examination Survey (NHANES) vs. National Cholesterol Education Program (NCEP) for predicting abnormal lipid levels in adulthood in a Middle East population. | BACKGROUND: To compare the predictive ability of adolescent lipoprotein classification using the National Examination Survey (NHANES) cut points and those of the National Cholesterol Education Program (NCEP) for predicting abnormal levels in adulthood.METHOD: From 1032 adolescents, aged 14-19 years, participants of the... | ['Adolescent', 'Area Under Curve', 'Dyslipidemias', 'Female', 'Health Surveys', 'Humans', 'Iran', 'Lipids', 'Logistic Models', 'Male', 'Multivariate Analysis', 'National Health Programs', 'Odds Ratio', 'Prevalence', 'Prospective Studies', 'ROC Curve', 'Reference Values', 'Young Adult'] | 22,937,812 | [['M01.060.057'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['C18.452.584.500'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['D10'], ['E05.318.740.500.525', 'E05.318.740.600.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The effects of clipping on thoracic sympathetic nerve in rabbits: early and late histopathological findings. | BACKGROUND: The clipping of the thoracic sympathetic nerve, which has been a technique used for approximately the past 10 years, has rapidly become popular because of its "bring-back" claim. However, the information regarding the mechanism behind this claim is based on investigator's comments and has not been proven by... | ['Animals', 'Equipment Design', 'Fibrosis', 'Ganglia, Sympathetic', 'Necrosis', 'Nerve Degeneration', 'Nerve Regeneration', 'Rabbits', 'Surgical Instruments', 'Sympathectomy', 'Thoracic Nerves', 'Thoracotomy', 'Thorax', 'Time Factors', 'Titanium'] | 22,411,756 | [['B01.050'], ['E05.320'], ['C23.550.355'], ['A08.340.315.350', 'A08.800.050.300.300', 'A08.800.050.800.300'], ['C23.550.717'], ['C23.550.737'], ['G11.561.585', 'G16.762.611'], ['B01.050.150.900.649.313.968.700'], ['E07.858.700'], ['E04.525.210.105.800'], ['A08.800.800.720.800'], ['E04.928.760'], ['A01.923.761'], ['G01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ocular manifestations in Stevens-Johnson syndrome]. | A patient woman, 45 years old, showed bilateral corneal ulcers, symblepharon, milkish-white scars, cicatricial entropion, trichiasis, lacrimal hyposecretion within a Stevens-Johnson syndrome. Histological examination of the conjunctiva shows a necrosis process of epithelium with phlyctenular cavities and abundant subep... | ['Conjunctiva', 'Epithelium', 'Eye Diseases', 'Female', 'Humans', 'Middle Aged', 'Stevens-Johnson Syndrome'] | 2,533,369 | [['A09.371.060.200', 'A09.371.337.168'], ['A10.272'], ['C11'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.864.500', 'C17.800.174.600.900', 'C17.800.229.400.683', 'C17.800.865.475.683', 'C20.543.206.380.900', 'C25.100.468.380.900']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In vivo measurement of myocardial mass using nuclear magnetic resonance imaging. | To examine the accuracy of nuclear magnetic resonance imaging in measuring left ventricular mass, measurements of left ventricular mass made using this technique were compared with left ventricular weight in 10 mongrel dogs. Left ventricular myocardial volume was measured from five short-axis end-diastolic images that ... | ['Animals', 'Dogs', 'Heart Ventricles', 'Magnetic Resonance Spectroscopy', 'Organ Size'] | 3,711,507 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541.560'], ['E05.196.867.519'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Breast cancer detection in relation to oral contraception. | Analyses of tumor size and breast cancer stage were used to determine whether biased detection of breast cancer could have materially influenced estimates of risk associated with use of oral contraceptives. In a population-based case-control study conducted from 1980-1982, surveillance for breast cancer by breast exams... | ['Adult', 'Age Factors', 'Bias', 'Breast', 'Breast Neoplasms', 'Case-Control Studies', 'Contraceptives, Oral', 'Female', 'Humans', 'Mammography', 'Menopause', 'Middle Aged', 'Risk Factors', 'Self-Examination', 'Time Factors'] | 1,588,351 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['N05.715.350.150', 'N06.850.490.500'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D27.505.696.875.360.276.210', 'D27.505.954.705.360.276.210'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A lignin-specific peroxidase in tobacco whose antisense suppression leads to vascular tissue modification. | A tobacco peroxidase isoenzyme (TP60) was down-regulated in tobacco using an antisense strategy, this affording transformants with lignin reductions of up to 40-50% of wild type (control) plants. Significantly, both guaiacyl and syringyl levels decreased in essentially a linear manner with the reductions in lignin amou... | ['Amino Acid Sequence', 'Conserved Sequence', 'Down-Regulation', 'Gene Expression Regulation, Plant', 'Gene Silencing', 'Isoenzymes', 'Lignin', 'Mixed Function Oxygenases', 'Models, Molecular', 'Molecular Sequence Data', 'Oligonucleotides, Antisense', 'Peroxidases', 'Plant Stems', 'Plants, Genetically Modified', 'Tobac... | 12,946,415 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.580'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.308.375'], ['G05.308.203.374'], ['D08.811.348', 'D12.776.800.300'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['D08.811.682.690.708'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Melphalan, prednisone, thalidomide and defibrotide in relapsed/refractory multiple myeloma: results of a multicenter phase I/II trial. | BACKGROUND: Defibrotide is a novel orally bioavailable polydisperse oligonucleotide with anti-thrombotic and anti-adhesive effects. In SCID/NOD mice, defibrotide showed activity in human myeloma xenografts. This phase I/II study was conducted to identify the most appropriate dose of defibrotide in combination with melp... | ['Antineoplastic Combined Chemotherapy Protocols', 'Dose-Response Relationship, Drug', 'Humans', 'Melphalan', 'Multiple Myeloma', 'Polydeoxyribonucleotides', 'Prednisone', 'Salvage Therapy', 'Thalidomide', 'Treatment Outcome'] | 20,053,869 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.728.650.594', 'D12.125.072.050.685.500'], ['C04.557.595.500', 'C14.907.454.460', 'C15.378.147.780.650', 'C15.378.463.515.460', 'C20.683.515.845', 'C20.683.78... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The isolation of a mutation causing abnormal cytokinesis in male and split chromocenter in female meiosis in Drosophila melanogaster. | The genetic screen for the meiotic mutations showing chromosome non-disjunction in mosaic clones of female germ line generated by FLP-FRT mediated mitotic recombination was performed. The sterile meiotic mutation ff16 (69D1-70A2) was found among the mutants obtained. In the male germ line the mutation showed lack of me... | ['Animals', 'Cell Division', 'Drosophila melanogaster', 'Female', 'Homozygote', 'Hot Temperature', 'Infertility, Male', 'Male', 'Meiosis', 'Mutation', 'Recombination, Genetic', 'Sperm Motility', 'Time Factors'] | 11,732,848 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.380.554'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['C12.294.365.700'], ['G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots. | BACKGROUND: Purine nucleoside phosphorylase (PNP) deficiency is a rare form of autosomal recessive combined primary immunodeficiency caused by a enzyme defect leading to the accumulation of inosine, 2'-deoxy-inosine (dIno), guanosine, and 2'-deoxy-guanosine (dGuo) in all cells, especially lymphocytes. Treatments are av... | ['Adolescent', 'Child, Preschool', 'DNA Repair', 'Deoxyguanosine', 'Dried Blood Spot Testing', 'Female', 'Guanosine', 'Humans', 'Immunologic Deficiency Syndromes', 'Infant', 'Infant, Newborn', 'Inosine', 'Lymphocytes', 'Male', 'Mutation', 'Neonatal Screening', 'Primary Immunodeficiency Diseases', 'Purine-Nucleoside Pho... | 24,767,876 | [['M01.060.057'], ['M01.060.406.448'], ['G02.111.222', 'G05.219'], ['D03.633.100.759.590.454.240', 'D13.570.230.360', 'D13.570.583.454.240'], ['E01.370.225.124.100.232', 'E05.200.124.100.232'], ['D03.633.100.759.590.454', 'D13.570.583.454', 'D13.570.800.453'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.673'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Heat transfer model of hyporthermic intracarotid infusion of cold saline for stroke therapy. | A 3-dimensional hemispheric computational brain model is developed to simulate infusion of cold saline in the carotid arteries in terms of brain cooling for stroke therapy. The model is based on the Pennes bioheat equation, with four tissue layers: white matter, gray matter, skull, and scalp. The stroke lesion is simul... | ['Body Temperature', 'Brain', 'Carotid Arteries', 'Cold Temperature', 'Computer Simulation', 'Energy Transfer', 'Humans', 'Hypothermia, Induced', 'Infusions, Intra-Arterial', 'Models, Biological', 'Sodium Chloride', 'Stroke', 'Therapy, Computer-Assisted', 'Thermal Conductivity', 'Treatment Outcome'] | 17,946,821 | [['E01.370.600.875.374', 'G07.110'], ['A08.186.211'], ['A07.015.114.186'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['L01.224.160'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The X proteins of bornaviruses interfere with type I interferon signalling. | Borna disease virus (BDV) is a neurotropic, negative-stranded RNA virus causing persistent infection and progressive neurological disorders in a wide range of warm-blooded animals. The role of the small non-structural X protein in viral pathogenesis is not completely understood. Here we investigated whether the X prote... | ['Animals', 'Bornaviridae', 'Cell Line', 'Epithelial Cells', 'Genes, Reporter', 'Humans', 'Immune Evasion', 'Interferon Type I', 'Luciferases', 'Molecular Sequence Data', 'RNA, Viral', 'Sequence Analysis, DNA', 'Viral Nonstructural Proteins', 'Virulence Factors'] | 23,100,370 | [['B01.050'], ['B04.820.480.937.149'], ['A11.251.210'], ['A11.436'], ['G05.360.340.024.340.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.462.400', 'G12.413', 'G16.527.200.700'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['D08.811.682.517', 'D12.776.532.510'], ['L01.4... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Circulating levels of insulin-like growth factor I, its binding proteins -1,-2, -3, C-peptide and risk of postmenopausal breast cancer. | Higher levels of circulating Insulin-like Growth Factor (IGF)-I may be associated with higher risks for premenopausal breast cancer. We investigate the associations between circulating levels of IGF-I, its binding proteins (IGFBPs) -1, -2, -3, C-peptide and postmenopausal breast cancer. This is a prospective study nest... | ['Aged', 'Apoptosis', 'Breast Neoplasms', 'C-Peptide', 'Cohort Studies', 'Female', 'Humans', 'Insulin-Like Growth Factor Binding Protein 1', 'Insulin-Like Growth Factor Binding Protein 2', 'Insulin-Like Growth Factor Binding Protein 3', 'Insulin-Like Growth Factor I', 'Middle Aged', 'Odds Ratio', 'Postmenopause', 'Pros... | 12,794,762 | [['M01.060.116.100'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.420.250'], ['D12.776.157.420.260'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Response to metronomic chemotherapy in a metastatic adenoid cystic carcinoma of the parotid gland]. | Formerly, salivary gland cancer was considered to be chemoresistant. Chemotherapy is indicated when distant metastases or inoperable locorregional disease are observed, although the chemotherapy schedule is not well defined. Data on chemotherapy treatment for adenoid cystic carcinoma consist of phase II trials. Most of... | ['Antineoplastic Agents', 'Carcinoma, Adenoid Cystic', 'Cisplatin', 'Drug Administration Schedule', 'Female', 'Humans', 'Middle Aged', 'Paclitaxel', 'Parotid Neoplasms'] | 20,152,955 | [['D27.505.954.248'], ['C04.557.470.200.025.220'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.455.426.392.368.242.888.777', 'D02.455.849.291.850.777'], ['C04.588.443.591.824.695', 'C07.465.530.824.695', 'C07.465.815.470.770... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pre-cannulation lung biopsy shortens ECMO course. | We describe the clinical course of an infant with respiratory failure who underwent lung biopsy prior to cannulation for undergoing extracorporeal membrane oxygenation (ECMO). Pathology revealed alveolar capillary dysplasia, and ECMO was discontinued. Rapid diagnosis allowed for closure and saved resources. We recommen... | ['Biopsy', 'Catheterization', 'Extracorporeal Membrane Oxygenation', 'Humans', 'Infant, Newborn', 'Lung', 'Male', 'Persistent Fetal Circulation Syndrome', 'Pulmonary Alveoli', 'Respiratory Insufficiency'] | 27,086,306 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E02.148', 'E05.157'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A04.411'], ['C08.381.423.694', 'C16.614.694'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Metabolism of synthetic cannabinoids PB-22 and its 5-fluoro analog, 5F-PB-22, by human hepatocyte incubation and high-resolution mass spectrometry. | BACKGROUND: PB-22 (1-pentyl-8-quinolinyl ester-1H-indole-3-carboxylic acid) and 5F-PB-22 (1-(5-fluoropentyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid) are new synthetic cannabinoids with a quinoline substructure and the first marketed substances with an ester bond linkage. No human metabolism data are currently a... | ['Cannabinoids', 'Cells, Cultured', 'Hepatocytes', 'Humans', 'Hydrolysis', 'Indoles', 'Oxidation-Reduction', 'Spectrometry, Mass, Electrospray Ionization', 'Tandem Mass Spectrometry'] | 24,518,903 | [['D02.455.849.090'], ['A11.251'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['D03.633.100.473'], ['G02.700', 'G03.295.531'], ['E05.196.566.600'], ['E05.196.566.880']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
IgE response in multiple myeloma. | IgE levels in sera of patients with multiple myeloma (MM) were found to be similar to those of patients with monoclonal gammopathy of unknown significance (MGUS) and to normal controls. This is in contrast to the significant depression in the level of the other polyclonal isotypes in patients with MM. Immediate skin te... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Female', 'Follow-Up Studies', 'Humans', 'Immunoglobulin A', 'Immunoglobulin E', 'Immunoglobulin G', 'Immunoglobulin M', 'Male', 'Melphalan', 'Middle Aged', 'Multiple Myeloma', 'Paraproteinemias', 'Skin Tests'] | 8,452,316 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['D12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metastasis-suppressed C8161 melanoma cells arrest in lung but fail to proliferate. | The incidence of melanoma continues to increase at a rapid rate. As for most cancers, it is melanoma metastases, rather than the primary malignancy, that is the principal cause of death. We previously showed that the introduction of a normal copy of chromosome 6 into the metastatic human melanoma cell line C8161 suppre... | ['Animals', 'Cell Division', 'Cell Survival', 'Chromosomes, Human, Pair 6', 'Female', 'Gene Transfer Techniques', 'Genes, Reporter', 'Genes, Tumor Suppressor', 'Green Fluorescent Proteins', 'Humans', 'Hybrid Cells', 'Injections, Intradermal', 'Injections, Intravenous', 'Luminescent Proteins', 'Lung Neoplasms', 'Melanom... | 10,845,559 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['A11.284.187.520.300.325.330', 'G05.360.162.520.300.325.330'], ['E05.393.350'], ['G05.360.340.024.340.435'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['D12.776.532.265'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mixed endometrial carcinomas with a "low-grade serous"-like component: a clinicopathologic, immunohistochemical, and molecular genetic study. | Recently, we reported 2 mixed endometrioid endometrial carcinomas with a "low-grade serous"-like component, which does not fit into any of the 4 molecular groups described by The Cancer Genome Atlas. To understand the nature of these tumors, we have done an immunohistochemical and molecular genetic study of these 2 cas... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Carcinoma, Endometrioid', 'Cystadenocarcinoma, Serous', 'DNA Mutational Analysis', 'Endometrial Neoplasms', 'Female', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'Mutation', 'Neoplasms, Complex and Mixed', 'Ovarian Neoplasms', 'Proto-Oncogene Proteins p21(ras)', 'Receptors, ... | 29,079,180 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['E05.393.760.700.300'], ['C04.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Copy number variations in a population-based study of Charcot-Marie-Tooth disease. | Copy number variations (CNVs) are important in relation to diversity and evolution but can sometimes cause disease. The most common genetic cause of the inherited peripheral neuropathy Charcot-Marie-Tooth disease is the PMP22 duplication; otherwise, CNVs have been considered rare. We investigated CNVs in a population-b... | ['Adult', 'Charcot-Marie-Tooth Disease', 'Child', 'DNA Copy Number Variations', 'Female', 'Genetic Association Studies', 'Genotype', 'Humans', 'Laminin', 'Male', 'Membrane Proteins', 'Nerve Tissue Proteins', 'Peripheral Nervous System Diseases', 'Phenotype', 'Point Mutation', 'Semaphorins'] | 25,648,254 | [['M01.060.116'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['M01.060.406'], ['G05.365.795.297.500'], ['E05.393.385'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.530', 'D12.776.543.550.500', 'D12.776.860.300.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A 3-year clinical evaluation of a compomer, a composite and a compomer/composite (sandwich) in class II restorations. | PURPOSE: To compare the clinical performance of Dyract, Spectrum-TPH and Dyract layered with Spectrum-TPH (sandwich) in Class II restorations of permanent dentitions.MATERIALS AND METHODS: 23 adult patients aged 25-62 were selected at random in a general dental practice. Each patient had 3 bicuspid teeth restored with ... | ['Acetone', 'Adult', 'Bicuspid', 'Chi-Square Distribution', 'Compomers', 'Composite Resins', 'Dental Marginal Adaptation', 'Dental Restoration Failure', 'Dental Restoration Wear', 'Dental Restoration, Permanent', 'Female', 'Humans', 'Male', 'Methacrylates', 'Middle Aged', 'Molar', 'Polymethacrylic Acids', 'Resin Cement... | 12,572,648 | [['D02.522.064'], ['M01.060.116'], ['A14.549.167.860.150'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D05.750.716.822.308.300', 'D25.339.291.150', 'D25.339.816.500.300', 'D25.720.716.822.308.300', 'J01.637.051.339.291.150', 'J01.637.051.339.816.500.300', 'J01.637.05... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Increased prevalence of coronary artery disease risk markers in patients with chronic hepatitis C--a cross-sectional study. | OBJECTIVE: Chronic hepatitis C is a global health problem and has been associated with coronary artery disease. Our aim was to examine the prevalence of coronary artery disease risk markers including endothelial biomarkers in patients with chronic hepatitis C and matched comparisons without manifest cardiovascular dise... | ['Adult', 'Biomarkers', 'Carotid Artery Diseases', 'Case-Control Studies', 'Coronary Artery Disease', 'Cross-Sectional Studies', 'Denmark', 'Dyslipidemias', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Hypertension', 'Inflammation Mediators', 'Lipids', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Predictive Value of T... | 24,482,574 | [['M01.060.116'], ['D23.101'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.816.12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
High Incidence of Breast Cancer in Light-Polluted Areas with Spatial Effects in Korea. | We have reported a high prevalence of breast cancer in light-polluted areas in Korea. However, it is necessary to analyze the spatial effects of light polluted areas on breast cancer because light pollution levels are correlated with region proximity to central urbanized areas in studied cities. In this study, we appli... | ['Breast Neoplasms', 'Circadian Rhythm', 'Cities', 'Environmental Pollution', 'Female', 'Humans', 'Incidence', 'Light', 'Prevalence', 'Republic of Korea', 'Risk Factors'] | 26,838,238 | [['C04.588.180', 'C17.800.090.500'], ['G07.180.562.190'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['N06.850.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['G01.358.500.505.650', 'G01.590.54... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Survival and prognostic factors in cerebral metastases of breast cancer]. | A number of prognostic factors have emerged from a retrospective study of 83 patients with breast cancer associated with a solid intracerebral tumour (59%), or meningeal invasion (33%) or both (8%). The median survival was 4 months without significant difference between breast tumours and meningeal carcinomatosis. Wome... | ['Brain Neoplasms', 'Breast Neoplasms', 'Central Nervous System Diseases', 'Female', 'Humans', 'Meningeal Neoplasms', 'Menopause', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Time Factors'] | 2,941,746 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.588.180', 'C17.800.090.500'], ['C10.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.250.580', 'C10.551.240.500'], ['G08.686.157.500', 'G08.686.841.249.500'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of oxygen toxicity on regional ventilation and perfusion in the primate lung. | Since the effect of prolonged exposure to high concentrations of oxygen on regional ventilation and perfusion has not been previously, a reproducible primate model of oxygen toxicity was developed to investigate the pathophysiologic changes that occur. Regional ventilation and perfusion were measured by 133Xe technique... | ['Animals', 'Hemodynamics', 'Lung', 'Male', 'Models, Biological', 'Oxygen', 'Papio', 'Respiration', 'Ventilation-Perfusion Ratio'] | 7,221,886 | [['B01.050'], ['G09.330.380'], ['A04.411'], ['E05.599.395'], ['D01.268.185.550', 'D01.362.670'], ['B01.050.150.900.649.313.988.400.112.199.120.610'], ['G09.772.705'], ['E01.370.386.700.650.900', 'G09.772.920']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Surgical outcomes of patients with iridocorneal endothelial syndrome: a case series. | The purpose of this study is to report the intermediate-term surgical outcomes of patients with iridocorneal endothelial syndrome-related glaucoma. The medical records of four patients (five eyes) surgery (Ahmed glaucoma valve implantation surgery and EX-PRESS mini shunt) were retrospectively reviewed. Median follow-up... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Glaucoma', 'Glaucoma Drainage Implants', 'Humans', 'Intraocular Pressure', 'Iridocorneal Endothelial Syndrome', 'Male', 'Middle Aged', 'Retrospective Studies', 'Tonometry, Ocular', 'Treatment Outcome', 'Visual Acuity'] | 27,495,952 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C11.525.381'], ['E07.695.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['C11.204.497', 'C11.941.375.322'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Distributed neural activity during object, spatial and integrated processing in humans. | Information about the form and the spatial location of objects is seamlessly integrated during visual perception. We used event-related potentials (ERPs) to explore neural activity related to processing form, location or the combination of both kinds of features. Healthy subjects performed three versions of a 'match-to... | ['Adult', 'Brain', 'Cognition', 'Electroencephalography', 'Electrooculography', 'Event-Related Potentials, P300', 'Female', 'Form Perception', 'Humans', 'Male', 'Psychomotor Performance', 'Space Perception'] | 12,706,225 | [['M01.060.116'], ['A08.186.211'], ['F02.463.188'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.380.230.285', 'E01.370.405.245.787.285'], ['G07.265.216.500.350', 'G11.561.200.500.350'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808', 'G11.427.700', 'G11.561... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Low-rank representation with adaptive graph regularization. | Low-rank representation (LRR) has aroused much attention in the community of data mining. However, it has the following twoproblems which greatly limit its applications: (1) it cannot discover the intrinsic structure of data owing to the neglect of the local structure of data; (2) the obtained graph is not the optimal ... | ['Algorithms', 'Cluster Analysis', 'Data Mining', 'Machine Learning'] | 30,173,056 | [['G17.035', 'L01.224.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.313.500.750.280.199', 'L01.470.625'], ['G17.035.250.500', 'L01.224.050.375.530']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Spatial distribution of polychlorinated biphenyls in coastal marine sediments receiving industrial effluents in Kuwait. | The concentrations of polychlorinated biphenyls (PCBs) were measured in surficial sediments receiving industrial and municipal effluents in Kuwait. The SigmaPCB concentrations varied by two orders of magnitude ranging from 0.4 to 84 microg kg(-1) dw. The homologue distribution in the study favored the more chlorinated ... | ['Carbon', 'Environmental Monitoring', 'Geologic Sediments', 'Industrial Waste', 'Kuwait', 'Petroleum', 'Polychlorinated Biphenyls', 'Power Plants', 'Seawater', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 16,205,983 | [['D01.268.150'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['D20.944.420', 'N06.850.460.710.420'], ['Z01.252.245.500.425'], ['D20.345.630', 'N06.230.132.258.630'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['J01.780', 'J03.540.680'], ['G16.500.275.725.500'... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
An aid to computerization of Heyman's afterloading system. | The authors describe a new type of dummy implant for use in the Heyman afterloading system. Inactive dummies with the same dimensions as the radioactive sources are loaded into the capsules before obtaining the orthogonal radiographs. The actual sources are not inserted until computer verification of satisfactory dose ... | ['Computers', 'Humans', 'Radiotherapy', 'Radiotherapy Dosage'] | 847,223 | [['L01.224.230.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.815'], ['E02.815.639']] | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Effect of bone marrow on healing of fractures, delayed unions and pseudoarthroses of long bones]. | Healing of long bones after autogenic bone marrow grafting have been monitored in 96 patients aged 36.6 on an average. Bone marrow was harvested from iliac crest and after mixing it with heparin grafted transcutaneously into the fracture site in 24 fracture patients. 42 delayed unions and 30 cases of pseudoarthrosis. P... | ['Adolescent', 'Adult', 'Aged', 'Bone Marrow Transplantation', 'Child', 'Female', 'Fracture Fixation, Internal', 'Fracture Healing', 'Fractures, Bone', 'Fractures, Ununited', 'Humans', 'Ilium', 'Male', 'Pseudarthrosis'] | 7,671,698 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.060.406'], ['E04.555.300.300'], ['G16.762.891.500'], ['C26.404'], ['C26.404.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825.434'], ['C26.404.468.627']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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