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Aggressive Palliation and Survival in Anaplastic Thyroid Carcinoma. | IMPORTANCE: Anaplastic thyroid carcinoma is an undifferentiated aggressive tumor with a high rate of regional and distant spread and a grave prognosis (median survival, 3 months) with no standardized treatment.OBJECTIVE: To review the effect of an active treatment policy on the outcome of anaplastic thyroid carcinoma.D... | ['Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Palliative Care', 'Prognosis', 'Retrospective Studies', 'Survival Rate', 'Thyroid Carcinoma, Anaplastic', 'Thyroid Neoplasms', 'Treatment Outcome'] | 26,512,447 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E02.760.666', 'N02.421.585.666'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence of overweight and obesity in older Mexican adults and its association with physical activity and related factors: An analysis of the study on global ageing and adult health. | OBJECTIVES: The obesity epidemic in Mexico is increasing and represents a considerable public health challenge. The population aged 50 years and older is also increasing and is not exempt from the obesity rise. We aimed to determine the current prevalence of Body Mass Index (BMI) categories in a sample of Mexicans aged... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Alcohol Drinking', 'Body Mass Index', 'Diet', 'Exercise', 'Female', 'Health Behavior', 'Health Status', 'Humans', 'Male', 'Mexico', 'Middle Aged', 'Obesity', 'Overweight', 'Prevalence', 'Residence Characteristics', 'Risk Factors', 'Smoking', 'Socioeconomic Factors'... | 25,339,538 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['F01.145.317.269'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G07.203.650.240'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.488'], ['I01.240.425', 'N01.224.42... | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Subdiaphragmatic bronchogenic cyst with gastric communication. | Upper gastrointestinal series and computed tomography of the abdomen in an elderly women demonstrated a large multiloculated mass in the left subphrenic space that communicated with the fundus. The resected specimen showed histopathological features of bronchopulmonary foregut malformation. | ['Bronchogenic Cyst', 'Diaphragm', 'Female', 'Gastric Fistula', 'Humans', 'Middle Aged', 'Radiography', 'Stomach'] | 3,169,478 | [['C04.182.195', 'C08.127.480', 'C08.695.195', 'C16.131.740.195'], ['A02.633.567.900.300'], ['C06.267.375', 'C23.300.575.185.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['A03.556.875.875']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Local vasodilator response to mobile phones. | OBJECTIVES: The use of mobile phones with the resulting generation of potentially harmful electromagnetic fields (EMF) is the focus of public interest. Heat generation and the activation of the inducible form of nitric oxide (NO) synthase may be possible causes of the biological effects of EMF exposure. We investigated... | ['Acoustics', 'Adult', 'Airway Resistance', 'Electromagnetic Fields', 'Female', 'Hot Temperature', 'Humans', 'Linear Models', 'Luminescent Measurements', 'Male', 'Microwaves', 'Nasal Cavity', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nose', 'Occipital Bone', 'Signal Processing, Computer-Assisted', 'Skin Temperature', '... | 11,192,886 | [['H01.671.031'], ['M01.060.116'], ['E01.370.386.700.050', 'G09.772.060'], ['G01.358.500.260', 'G01.358.750.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.5... | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
CNS pathways mediating cardiovascular regulation of vasopressin. | 1. The release of vasopressin from the neurohypophysial terminals of hypothalamic magnocellular neurosecretory neurons is subject to regulation by peripheral baroreceptors, cardiopulmonary volume receptors and circulating angiotensin II. Information from these sources is transmitted through different pathways to achiev... | ['Angiotensin II', 'Blood Pressure', 'Cardiovascular Physiological Phenomena', 'Hypotension', 'Hypothalamus', 'Neurosecretory Systems', 'Pressoreceptors', 'Shock', 'Subfornical Organ', 'Vasopressins'] | 8,819,645 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330'], ['C14.907.514'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['A06.688', 'A08.713'], ['A08.675.650.915.750.750... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myeloma-specific multiple peptides able to generate cytotoxic T lymphocytes: a potential therapeutic application in multiple myeloma and other plasma cell disorders. | PURPOSE: The efficacy of peptide vaccines may be enhanced by stimulating immune cells with multiple peptides derived from distinct tumor-associated antigens. We have evaluated the heteroclitic XBP1-US(184-192) (YISPWILAV), heteroclitic XBP1-SP(367-375) (YLFPQLISV), native CD138(260-268) (GLVGLIFAV), and native CS1(239-... | ['Antigens, Neoplasm', 'Cell Line, Tumor', 'Cell Proliferation', 'DNA-Binding Proteins', 'HLA-A2 Antigen', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Multiple Myeloma', 'Peptide Fragments', 'Peptides', 'Regulatory Factor X Transcription Factors', 'Syndecan-1', 'T-Lymphocytes, Cytotoxic', 'Transcription... | 22,753,586 | [['D23.050.285'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.776.260'], ['D12.776.395.550.489.400.020', 'D12.776.543.550.439.400.020', 'D23.050.301.500.100.400.020', 'D23.050.301.500.450.370.020', 'D23.050.705.552.100.400.020', 'D23.050.705.552.450.370.374'], ['B01.050.150.900... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The immunosuppressant leflunomide blocks the yeast Saccharomyces cerevisiae cell cycle at the G1 phase. | Leflunomide is a novel immunomodulatory drug representing a new small molecule class of substances which are structurally unrelated to previously described immunomodulatory/immunosuppressive compounds. The effect of leflunomide on the cell cycle of Saccharomyces cerevisiae was investigated to elucidate the molecular me... | ['Cell Cycle', 'Cell Division', 'Drug Resistance, Microbial', 'G1 Phase', 'Hot Temperature', 'Immunosuppressive Agents', 'Isoxazoles', 'Leflunomide', 'Mutation', 'Saccharomyces cerevisiae'] | 8,837,482 | [['G04.144'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G06.225', 'G07.690.773.984.269'], ['G04.144.500.320'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D27.505.696.477.656'], ['D03.383.129... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Array comparative genomic hybridization analysis of adult acute leukemia patients. | We have performed a retrospective array-based comparative hybridization (array-CGH) study on 41 acute leukemia samples [n=17 acute lymphoblastic leukemia (ALL) patients only at diagnosis, n=3 ALL patients both at diagnosis and relapse; n=20 acute myeloid leukemia (AML) patients only at diagnosis and n=1 AML patient bot... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chromosome Aberrations', 'Comparative Genomic Hybridization', 'Female', 'Humans', 'In Situ Hybridization, Fluorescence', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Mutation', 'Oligonucleotide Array Sequence Analysis', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Re... | 20,193,845 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.210', 'G05.365.590.175'], ['E05.393.285.240', 'E05.393.520.500', 'E05.393.661.187'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.7... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cell Surface N-Glycans Influence Electrophysiological Properties and Fate Potential of Neural Stem Cells. | Understanding the cellular properties controlling neural stem and progenitor cell (NSPC) fate choice will improve their therapeutic potential. The electrophysiological measure whole-cell membrane capacitance reflects fate bias in the neural lineage but the cellular properties underlying membrane capacitance are poorly ... | ['Acetylglucosamine', 'Animals', 'Astrocytes', 'Brain', 'Cell Differentiation', 'Cell Lineage', 'Cell Membrane', 'Cell Proliferation', 'Cell Size', 'Cell Survival', 'Electrophysiological Phenomena', 'Fucose', 'Gene Expression Regulation', 'Glycosylation', 'Mice', 'N-Acetylneuraminic Acid', 'Neural Stem Cells', 'Neuroge... | 30,197,120 | [['D09.067.342.531.050'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A11.284.149'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.325'], ['G04.346'], ['G07.265'], ['D09.254.488'], ['G05.308'], ['G02.111.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photodynamic treatment has chondroprotective effects on articular cartilage. | Osteoarthritis (OA) is a disabling joint disease for which there is currently no cure. It is characterized by the destruction of articular cartilage. One strategy that is being explored for protecting the cartilage in OA is the administration of transforming growth factor-beta, which in vitro antagonizes cartilage degr... | ['Animals', 'Animals, Newborn', 'Cartilage, Articular', 'Cattle', 'Glycosaminoglycans', 'In Vitro Techniques', 'Interleukin-1', 'Photochemotherapy', 'Polylysine', 'Porphyrins', 'Radiation-Sensitizing Agents', 'Transforming Growth Factor beta', 'Transforming Growth Factor beta1'] | 11,918,303 | [['B01.050'], ['B01.050.050.282'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.500.380.271'], ['D09.698.373'], ['E05.481'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['E02.186.500', 'E... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Value of various concepts in long-term electrocardiography]. | With the introduction of long-term ECG by N. Holter more than 25 years ago a more sensitive detection of spontaneous arrhythmias and ST-changes became possible compared with the standard ECG at rest. Unfortunately, visual high-speed analysis of the tapes caused remarkable loss of stored informations due to the failure ... | ['Arrhythmias, Cardiac', 'Cardiac Complexes, Premature', 'Diagnosis, Computer-Assisted', 'Electrocardiography', 'Humans', 'Monitoring, Physiologic', 'Prognosis', 'Signal Processing, Computer-Assisted'] | 2,451,360 | [['C14.280.067', 'C23.550.073'], ['C14.280.067.325', 'C14.280.123.375', 'C23.550.073.325'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520'], ['E01.789'], ['L01.224.800']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Catecholamines and hemorrhagic shock in awake and anesthetized rats. | Catecholamines in plasma and tissue were determined during hemorrhagic shock in the rat. Two groups of rats were compared. 1. Awake rats bled to 70 mm Hg for 4 hours. 2. Anesthetized rats (pentobarbital sodium 60 mg/kg) bled to 35 mm Hg for 4 hours. The mortality rate was similar in both groups. The bled volume was als... | ['Adrenal Glands', 'Anesthesia', 'Animals', 'Catecholamines', 'Dopamine', 'Epinephrine', 'Heart Rate', 'Male', 'Muscles', 'Myocardium', 'Norepinephrine', 'Rats', 'Shock, Hemorrhagic'] | 455,594 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytotoxicity and effect on collagen biosynthesis of proline analogue of melphalan as a prolidase-convertible prodrug in cultured human skin fibroblasts. | Proline analogue of melphalan (MEL-PRO) was synthesised as a prodrug susceptible to the action of ubiquitously distributed, cytosolic imidodipeptidase--prolidase [E.C.3.4.13.9]. Conjugation of melphalan (MEL) with proline (PRO) through an imido-bond resulted in formation of a good substrate for prolidase. The susceptib... | ['Antineoplastic Agents, Alkylating', 'Cell Survival', 'Cells, Cultured', 'Child', 'Collagen', 'Dipeptidases', 'Fibroblasts', 'Humans', 'Male', 'Melphalan', 'Prodrugs', 'Proline', 'Skin'] | 11,680,815 | [['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['G04.346'], ['A11.251'], ['M01.060.406'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D08.811.277.656.350.297'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.728.650.594', 'D12.125.072.050.685.500'], ['D26.675'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion. | The thymus is seeded by very small numbers of progenitor cells that undergo massive proliferation before differentiation and rearrangement of TCR genes occurs. Various signals mediate proliferation and differentiation of these cells, including Wnt signals. Wnt signals induce the interaction of the cytoplasmic cofactor ... | ['Animals', 'Antigens, CD34', 'Cell Adhesion', 'Cell Differentiation', 'Cell Division', 'Cell-Free System', 'Child', 'Cytoskeletal Proteins', 'DNA-Binding Proteins', 'Genes, Reporter', 'Hepatocyte Nuclear Factor 1-alpha', 'Humans', 'Lithium Chloride', 'Lymphoid Enhancer-Binding Factor 1', 'Mice', 'Mice, Inbred C57BL', ... | 14,707,084 | [['B01.050'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['G04.022'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.835.168'], ['M01.060.406'], ['D12.776.220'], ['D12.776.260'], ['G05.360.340.024.340.435'], ['D12.776.260.262.500.500', 'D12.776.260.400.218.500'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Attenuated expression of 70-kDa heat shock protein in WI-38 human fibroblasts during aging in vitro. | We examined the effects of cellular aging on the expression of the heat shock-inducible HSP70 gene in WI-38 diploid human fibroblasts serially passaged in vitro. The senescence of the cells was established by evaluating population doubling level, cell density at confluency, and cell morphology along with the detection ... | ['Base Sequence', 'Biomarkers', 'Cell Line', 'Cell Nucleus', 'Cellular Senescence', 'Culture Media, Serum-Free', 'Cytoplasm', 'DNA Primers', 'Fibroblasts', 'Gene Expression', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Response', 'Humans', 'In Vitro Techniques', 'RNA, Messenger', 'beta-Galactosidase'] | 10,502,396 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D23.101'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.043'], ['D27.720.470.305.255', 'E07.206.255'], ['A11.284.430.214'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A11.329.228'], ['G05.297'], ['D12.776.580.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The analysis of RCAS1 and DFF-45 expression in nasal polyps with respect to immune cells infiltration. | BACKGROUND: Nasal polyp constitutes a benign growth process in the nasal and sinus mucosa. RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) is a protein expressed mainly by various human cancer cells. It is not only the marker of cancer process and its expression can also be observed in physiological pro... | ['Adult', 'Antigens, Neoplasm', 'Apoptosis', 'Cell Movement', 'Eosinophils', 'Female', 'Humans', 'Lymphocytes', 'Male', 'Nasal Polyps', 'Neutrophils', 'Proteins'] | 16,551,346 | [['M01.060.116'], ['D23.050.285'], ['G04.146.954.035'], ['G04.198', 'G07.568.500.180'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['C08.460.572'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Time trends and geographic variations in the prevalence of hypospadias in China. | BACKGROUND: Little is known about the main epidemiologic characteristics of hypospadias prevalence in China. We investigated the time trends and geographic variations in the prevalence of hypospadias in China from 1996 to 2008.METHODS: Data were retrieved from the hospital-based birth defects monitoring system in China... | ['China', 'Congenital Abnormalities', 'Environmental Exposure', 'Female', 'Humans', 'Hypospadias', 'Infant, Newborn', 'Male', 'Maternal Age', 'Medical Records', 'Population Surveillance', 'Prevalence', 'Rural Population', 'Time Factors', 'Urban Population'] | 21,960,504 | [['Z01.252.474.164'], ['C16.131'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494.400', 'C12.706.516', 'C13.351.875.466', 'C16.131.939.516'], ['M01.060.703.520'], ['G08.686.560', 'N05.715.350.075.550', 'N06.850.490.250.550'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.3... | ['Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Management of persistent glaucoma secondary to depot methylprednisolone. | This article describes two patients with recalcitrant ocular hypertension persisting 6 and 4 months, respectively, after periocular injection of methylprednisolone acetate despite maximum medical therapy. White sub-Tenon's plaques of residual methylprednisolone acetate were excised surgically and analyzed for steroid a... | ['Adult', 'Anti-Inflammatory Agents', 'Glaucoma', 'Humans', 'Injections', 'Male', 'Methylprednisolone', 'Methylprednisolone Acetate', 'Ophthalmologic Surgical Procedures', 'Orbit', 'Panuveitis', 'Pars Planitis'] | 17,955,845 | [['M01.060.116'], ['D27.505.954.158'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['D04.210.500.745.432.769.795.539'], ['D04.210.500.745.432.769.795.539.250'], ['E04.540'], ['A02.835.232.781.324.690'], ['C11.941.879.780'], ['C11.941.160.478.700', 'C11.941.879.780.900.300.659'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Constructing mental illness as dangerous: a pilot study. | OBJECTIVE: There is a dearth of studies examining how dangerousness is constructed in media depictions of mentally ill individuals who are frequently portrayed as acting violently. The aim of the present study was to identify the contribution of diverse technical, semiotic and discursive resources utilised in portrayin... | ['Dangerous Behavior', 'Humans', 'Language', 'Mental Disorders', 'Music', 'Pilot Projects', 'Television'] | 10,336,222 | [['F01.145.263', 'I01.880.735.223'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F03'], ['K01.602'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['J01.897.280.500.898', 'L01.178.590.875', 'L01.178.820.090.898', 'L01.178.847.823']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Predictability of cerebral palsy in a high-risk NICU population. | AIM: This study aims to create a predictive model for the assessment of the individual risk of developing cerebral palsy in a large cohort of selected high-risk infants.PATIENTS AND METHODS: 1099 NICU-admitted high-risk infants were assessed up to the corrected age of at least 12 months. CP was categorized relative to ... | ['Cerebral Palsy', 'Cohort Studies', 'Echoencephalography', 'Female', 'Gestational Age', 'Humans', 'Infant', 'Infant, Newborn', 'Intensive Care Units, Neonatal', 'Logistic Models', 'Male', 'Pregnancy', 'Pregnancy, Multiple', 'Regression Analysis', 'Respiration, Artificial', 'Risk Assessment', 'Risk Factors'] | 20,542,648 | [['C10.228.140.140.254'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.578.937.260', 'E01.370.350.700.560.260', 'E01.370.350.850.260', 'E01.370.376.537.750.260', 'E05.629.937.260'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Intravenous immunoglobulin replacement therapy in the treatment of patients with common variable immunodeficiency disease: an open-label prospective study. | BACKGROUND: Common variable immunodeficiency (CVID) is characterized by humoral immunodeficiency resulting in increased susceptibility to infections and diminished responses to protein and polysaccharide vaccines. Intravenous immunoglobulins (IVIgs) constitute a replacement therapeutic regimen for CVID and other primar... | ['Adolescent', 'Adult', 'B-Lymphocytes', 'CD4-Positive T-Lymphocytes', 'Case-Control Studies', 'Common Variable Immunodeficiency', 'Female', 'Humans', 'Immunoglobulins, Intravenous', 'Interleukin-10', 'Interleukin-2', 'Male', 'Middle Aged', 'Prospective Studies', 'T-Lymphocytes, Regulatory', 'Time Factors', 'Young Adul... | 21,473,654 | [['M01.060.057'], ['M01.060.116'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.4... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of para-chlorophenylalanine and tryptophan on learning of a brightness discrimination in rats. | Both the learning of brightness discrimination, discrimination reversal and a simple oddity problem, and the pain-sensitivity to electric shock were studied in rats treated with 100 mg/kg of D, L-parachlorophenylalanine (PCPA), 100 mg/kg of D, L-tryptophan (TP) or 2.0 ml/kg of control solution (CS). At the end of the l... | ['Animals', 'Discrimination Learning', 'Fenclonine', 'Hydroxyindoleacetic Acid', 'Male', 'Photic Stimulation', 'Problem Solving', 'Rats', 'Reaction Time', 'Reversal Learning', 'Serotonin', 'Tryptophan'] | 136,233 | [['B01.050'], ['F02.463.425.280'], ['D12.125.072.050.685.440'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['E05.723.729'], ['F02.463.425.725', 'F02.463.785.810'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.425.798'], ['D02.092.211.215.801.8... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnosing smallpox: would you know it if you saw it? | The intentional release of anthrax in the United States in 2001 and other recent acts of terrorism have highlighted the possibility of intentional release of smallpox by terrorists. Little is known about physicians' ability to diagnose smallpox, especially in the critical first days, when the potential for rapid contro... | ['Attitude of Health Personnel', 'Chickenpox', 'Data Collection', 'Diagnosis, Differential', 'Emergency Medical Services', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Pediatrics', 'Physicians', 'Physicians, Family', 'Smallpox', 'Surveys and Questionnaires', 'Terrorism'] | 15,588,053 | [['F01.100.050', 'N05.300.100'], ['C01.925.256.466.930.250'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E01.171'], ['N02.421.297'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.670'], ['M01.526.485.810', 'N02.360.810'], ['M01.526.485.81... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Diagnosis of the nutcracker syndrome with color Doppler sonography: correlation with flow patterns on retrograde left renal venography. | OBJECTIVE: Our objective was to confirm flow patterns of the left renal vein and assess the usefulness of color Doppler sonography in the diagnosis of the renal vein entrapment, or nutcracker, syndrome.SUBJECTS AND METHODS: Forty-four patients with hematuria of unknown origin underwent color Doppler sonography, renal a... | ['Adolescent', 'Adult', 'Blood Flow Velocity', 'Constriction, Pathologic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peripheral Vascular Diseases', 'Radiography', 'Renal Veins', 'Sensitivity and Specificity', 'Syndrome', 'Ultrasonography, Doppler, Color'] | 9,888,735 | [['M01.060.057'], ['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['C23.300.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.907.617'], ['E01.370.350.700'], ['A07.015.908.752'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Linkage Disequilibrium Estimation in Low Coverage High-Throughput Sequencing Data. | High-throughput sequencing methods that multiplex a large number of individuals have provided a cost-effective approach for discovering genome-wide genetic variation in large populations. These sequencing methods are increasingly being utilized in population genetic studies across a diverse range of species. Two side-e... | ['Algorithms', 'Animals', 'Data Accuracy', 'Deer', 'Genome-Wide Association Study', 'Genotype', 'Heterozygote', 'Linkage Disequilibrium', 'Sequence Analysis, DNA'] | 29,588,288 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E05.318.308.028', 'E05.318.370.725.250', 'L01.399.250.202', 'N05.715.360.300.202', 'N05.715.360.325.685.250'], ['B01.050.150.900.649.313.500.380.373'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Follicular populations, recruitment and atresia in the ovaries of different strains of mice. | Follicular atresia is a key event in the selection of the ovulatory follicles and occurs during all developmental stages. The aims of the study were to evaluate the follicular population as well as the rates of follicular recruitment and atresia in different strains of mice. Ovaries were obtained from four strains of m... | ['Animals', 'Apoptosis', 'Caspase 3', 'Female', 'Follicular Atresia', 'Granulosa Cells', 'Immunohistochemistry', 'Mice', 'Mice, Inbred C57BL', 'Oocytes', 'Ovarian Follicle', 'Ovary', 'Species Specificity'] | 22,472,939 | [['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['G08.686.290'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812', 'A11.436.329'], ['E01.370.225.500.607.512', 'E01.370... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Purification, crystallization and preliminary X-ray diffraction analysis of the carbohydrate-binding region of the Streptococcus gordonii adhesin GspB. | The carbohydrate-binding region of the bacterial adhesin GspB from Streptococcus gordonii strain M99 (GspB(BR)) was expressed in Escherichia coli and purified using affinity and size-exclusion chromatography. Separate sparse-matrix screening of GspB(BR) buffered in either 20 mM Tris pH 7.4 or 20 mM HEPES pH 7.5 resulte... | ['Adhesins, Bacterial', 'Crystallization', 'Crystallography, X-Ray', 'Streptococcus gordonii'] | 21,045,307 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['B03.353.750.737.872.260', 'B03.510.400.800.872.260', 'B03.510.550.737.872.260']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Infectious complications in children with end-stage renal disease on replacement therapy]. | BACKGROUND: Annually, 5000 children younger than 20 years of age and 200 younger than two-years require treatment for chronic kidney disease (CKD). The objective was to estimate the incidence rate of infectious complications in children requiring renal replacement therapy.METHODS: Retrospective cohort. Patients with a ... | ['Adolescent', 'Bacteremia', 'Candidiasis', 'Catheter-Related Infections', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Gram-Negative Bacterial Infections', 'Gram-Positive Bacterial Infections', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Mal... | 26,509,300 | [['M01.060.057'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['C01.150.703.160'], ['C01.195'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C01.150.252.400'], ['C01.150.252.410'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Estimating subcatchment runoff coefficients using weather radar and a downstream runoff sensor. | This paper presents a method for estimating runoff coefficients of urban drainage subcatchments based on a combination of high resolution weather radar data and flow measurements from a downstream runoff sensor. By utilising the spatial variability of the precipitation it is possible to estimate the runoff coefficients... | ['Cities', 'Denmark', 'Models, Theoretical', 'Radar', 'Rain', 'Water Movements', 'Water Supply'] | 24,056,426 | [['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['Z01.542.816.124'], ['E05.599'], ['L01.178.847.500'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850'], ['J01.293.821.500']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Tissue-specific expression of the tight junction proteins claudins and occludin in the rat salivary glands. | Tight junctions (TJs) are essential features of endothelial barrier membranes and of fluid-secreting epithelial cells, such as in the salivary glands. Novel integral membrane proteins have been identified as components of TJs, namely claudins and occludin. The aim of the present study was to determine the distribution ... | ['Animals', 'Claudin-1', 'Claudin-3', 'Claudin-4', 'Cryopreservation', 'Fluorescent Antibody Technique', 'Male', 'Membrane Proteins', 'Microscopy, Confocal', 'Occludin', 'Rats', 'Rats, Sprague-Dawley', 'Salivary Glands', 'Tight Junctions'] | 15,447,685 | [['B01.050'], ['D12.776.543.940.200.100'], ['D12.776.543.940.200.300'], ['D12.776.543.940.200.400'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spatial variability of bacteria in the rhizosphere of Elsholtzia splendens under Cu contamination. | Elsholtzia splendens is a well-known Cu-tolerant plant; yet, the impact of Cu-contaminated soil on bacterial community in its rhizosphere is not known. We studied the spatial variability of bacteria in the rhizosphere using Cu-contaminated soil with polymerase chain reaction-denaturing gradient gel electrophoresis (PCR... | ['Bacteria', 'Copper', 'Gene Expression', 'Lamiaceae', 'Plant Roots', 'Rhizosphere', 'Soil Microbiology', 'Soil Pollutants'] | 24,801,294 | [['B03'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G05.297'], ['B01.650.940.800.575.912.250.583.520'], ['A18.400'], ['G16.500.275.157.625', 'G16.500.853', 'N06.230.124.437'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['D27.888.284.756']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Cytological analysis of atypical squamous epithelial cells of undetermined significance using the world wide web. | OBJECTIVE: The low-level consistency of the cytodiagnosis of uterine cervical atypical squamous epithelial cells of undetermined significance (ASC-US) employing the Bethesda System has been reported, suggesting the necessity of a wide survey. We presented cases judged as ASC-US on the Web and analyzed the voting result... | ['Carcinoma, Squamous Cell', 'Cervical Intraepithelial Neoplasia', 'Cervix Uteri', 'Cytodiagnosis', 'Female', 'Humans', 'Internet', 'Precancerous Conditions', 'Prognosis', 'Uterine Cervical Dysplasia', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 21,791,900 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.557.470.200.240.250'], ['A05.360.319.679.256'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['C04.834'], ['E01.789'], ['C04.834.818', 'C13.351.500.852.593.074'], ['C04.588.945.... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reproducible and quantitative model of infection of Dermacentor variabilis with the live vaccine strain of Francisella tularensis. | Pathogen life cycles in mammalian hosts have been studied extensively, but studies with arthropod vectors represent considerable challenges. In part this is due to the difficulty of delivering a reproducible dose of bacteria to follow arthropod-associated replication. We have established reproducible techniques to intr... | ['Animal Structures', 'Animals', 'Bacterial Vaccines', 'Dermacentor', 'Disease Models, Animal', 'Disease Transmission, Infectious', 'Disease Vectors', 'Francisella tularensis', 'Mice', 'Reproducibility of Results', 'Tularemia', 'Vaccines, Attenuated'] | 25,362,054 | [['A13'], ['B01.050'], ['D20.215.894.135'], ['B01.050.500.131.166.132.832.400.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['N06.850.335'], ['N06.850.335.188', 'N06.850.520.203.375'], ['B03.440.400.425.340.590', 'B03.660.250.200.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.318.370.725', 'E05.337.8... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Efficacy of rivastigmine on activities of daily living in Sri Lankan patients with Alzheimer disease and on improving caregiver burden: a prospective study. | OBJECTIVE: This open label, parallel group, prospective cohort study investigated the efficacy of rivastigmine treatment on activities of daily living (ADL) in patients with mild to moderate Alzheimer's disease (AD) and the possible benefits of this therapy on caregiver stress levels.METHODS: Thirty eight consecutive p... | ['Adult', 'Aged', 'Alzheimer Disease', 'Caregivers', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Phenylcarbamates', 'Probability', 'Prospective Studies', 'Quality of Life', 'Reference Values', 'Risk Assessment', 'Rivastigmine', 'Se... | 16,252,573 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'G... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Long-term treatment results of postoperative radiation therapy for advanced stage oropharyngeal carcinoma. | BACKGROUND: The authors report the long-term treatment results for advanced stage base of tongue (BOT) and tonsillar fossa (TF) carcinomas treated with surgery and postoperative radiation therapy (RT) at Memorial Sloan-Kettering Cancer Center.METHODS: Between 1973 and 1986, 51 patients with squamous cell carcinoma of t... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Oropharyngeal Neoplasms', 'Postoperative Period', 'Radiotherapy', 'Retrospective Studies', 'Survival Analysis', 'Tongue Neoplasms', 'Tonsillar Neoplasms'] | 1,423,170 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['C04.588.443.665.710.684', 'C07.550... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genome-wide search for markers associated with osteochondrosis in Hanoverian warmblood horses. | A genome-wide scan was performed to detect quantitative trait loci (QTLs) for osteochondrosis (OC) and osteochondrosis dissecans (OCD) in horses. The marker set comprised 260 microsatellites. We collected data from 211 Hanoverian warmblood horses consisting of 14 paternal half-sib families. Traits used were OC (fetlock... | ['Animals', 'Chromosome Mapping', 'Chromosomes', 'Genetic Linkage', 'Genetic Markers', 'Genome', 'Horse Diseases', 'Horses', 'Microsatellite Repeats', 'Osteochondritis', 'Phenotype', 'Quantitative Trait Loci'] | 17,906,894 | [['B01.050'], ['E05.393.183'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['G05.360.340'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['C05.116.791', 'C05.18... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Vitamin D deficit in adult women living in Buenos Aires City]. | Vitamin D deficiency is a common cause of morbidity. We prospectively studied 224 consecutive female patients in order to evaluate the prevalence of vitamin D deficiency and to assess the utility of various clinical and biochemical markers in predicting the deficiency. All of them were outpatients, 30 years old or olde... | ['Adult', 'Age Factors', 'Argentina', 'Body Mass Index', 'Body Weight', 'Calcium', 'Epidemiologic Methods', 'Female', 'Humans', 'Male', 'Menopause', 'Middle Aged', 'Postmenopause', 'Premenopause', 'Vitamin D', 'Vitamin D Deficiency'] | 20,053,603 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.107.757.077'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D01.268.552.100', 'D01.552.5... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Urinary excretion of 3-methylhistidine and creatinine and plasma concentrations of amino acids in hyperthyroid patients following preoperative treatment with antithyroid drug or beta-blocking agent: results from a prospective, randomized study. | The aim of this investigation was to compare the effects of a beta 1-selective adrenoceptor blocking agent and an antithyroid drug on urinary excretion of creatinine (Cr) and 3-methylhistidine (3-MH) and plasma concentrations of amino acids in hyperthyroid patients. beta-adrenoceptor blocking agents are increasingly us... | ['Adult', 'Amino Acids', 'Creatinine', 'Female', 'Humans', 'Hyperthyroidism', 'Male', 'Methimazole', 'Methylhistidines', 'Metoprolol', 'Middle Aged', 'Preoperative Care', 'Prospective Studies', 'Proteins', 'Random Allocation', 'Thyroxine', 'Triiodothyronine'] | 3,600,277 | [['M01.060.116'], ['D12.125'], ['D03.383.129.308.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['D02.886.489.600', 'D03.383.129.308.535'], ['D12.125.072.329.539'], ['D02.033.100.624.698.573', 'D02.033.755.624.698.573', 'D02.092.063.624.698.573'], ['M01.060.116.630'], ['E02.760.795', 'E04.604.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Bone morphogenetic protein-2-encupsulated PEG-grafted-poly-lactic acid-polycaprolactone nanoparticles promote bone repair]. | OBJECTIVE: To explore the efficacy of a novel tissue engineered bone in repairing bone defects using poly-lactic acid-polycaprolactone (PLA-PCL) scaffolding seeded with PEG-bone morphogenetic protein-2 (BMP-2) transfected rBMSCs (rabbit bone marrow stromal cells).METHODS: rBMSCs were harvested, transfected with PEG/BMP... | ['Animals', 'Bone Morphogenetic Protein 2', 'Bone and Bones', 'Enzyme-Linked Immunosorbent Assay', 'Mesenchymal Stem Cells', 'Nanoparticles', 'Polyesters', 'Polyethylene Glycols', 'Rabbits', 'Real-Time Polymerase Chain Reaction', 'Transfection'] | 26,080,923 | [['B01.050'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['A02.835.232', 'A10.165.265'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A11.329.830.500', 'A11.872.590.500'], ['J01.637.512.600'], ['D05.750.728', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Acute effects of tobacco smoke on alveolar macrophages cultured in gas phase. | With a culture technique in gaseous phase which permits a direct contact between cells and the atmosphere, without any liquid interposition, we studied the short-term effects of tobacco smoke on guinea pig alveolar macrophages (AM). Tobacco smoke had a cytotoxic effect on AM as evaluated by the decrease in cell ATP con... | ['Adenosine Triphosphate', 'Animals', 'Blood Bactericidal Activity', 'Cell Survival', 'Cells, Cultured', 'Glutathione', 'Guinea Pigs', 'In Vitro Techniques', 'Macrophages', 'Plants, Toxic', 'Pulmonary Alveoli', 'Smoke', 'Time Factors', 'Tobacco'] | 3,862,613 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['G09.188.100', 'G12.450.564.204'], ['G04.346'], ['A11.251'], ['D12.644.456.448'], ['B01.050.150.900.649.313.992.550'], ['E05.481'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.650... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term impact of sulfate on an autotrophic nitrogen removal system integrated partial nitrification, anammox and endogenous denitrification (PAED). | A nitrogen removal system integrating partial nitrification, anaerobic ammonium oxidation (Anammox) and endogenous denitrification (PAED) was established in a sequencing batch reactor (SBR) for treating low nitrogen sewage (approximately 40 mg L-1 ammonia-nitrogen). The impact of sulfate on PAED sludge was investigated... | ['Ammonia', 'Autotrophic Processes', 'Bioreactors', 'Denitrification', 'Nitrification', 'Nitrogen', 'Oxidation-Reduction', 'Sewage', 'Sulfates'] | 31,265,979 | [['D01.362.075', 'D01.625.050'], ['G02.111.071', 'G03.087'], ['E07.115', 'J01.897.120.115'], ['G02.111.587.250', 'G02.607.560.250', 'G16.500.768.249'], ['G02.111.587.500', 'G02.607.560.500', 'G16.500.768.500'], ['D01.268.604', 'D01.362.625'], ['G02.700', 'G03.295.531'], ['D20.944.932.500'], ['D01.248.497.158.845', 'D01... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Women veterans' experience with a web-based diabetes prevention program: a qualitative study to inform future practice. | BACKGROUND: Diabetes prevention is a national goal and particularly important in the Veterans Health Administration (VHA) where 1 in 4 veterans has diabetes. There is growing evidence to support the use of Web-based diabetes prevention program (DPP) interventions, shown to be as effective and often more feasible than i... | ['Adult', 'Attitude to Computers', 'Diabetes Mellitus', 'Disease Management', 'Female', 'Humans', 'Internet', 'Qualitative Research', 'Telemedicine', 'United States', 'Veterans'] | 26,006,697 | [['M01.060.116'], ['F01.100.100'], ['C18.452.394.750', 'C19.246'], ['N04.590.607'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['H01.770.644.241.850'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800'], ['Z01.107.567.875'], ['M01.930']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Role of the chromobox protein CBX7 in lymphomagenesis. | Chromobox 7 (CBX7) is a chromobox family protein and a component of the Polycomb repressive complex 1 (PRC1) that extends the lifespan of cultured epithelial cells and can act independently of BMI-1 to repress the INK4a/ARF tumor suppressor locus. To determine whether CBX7 might be oncogenic, we examined its expression... | ['Animals', 'Cyclin-Dependent Kinase Inhibitor p16', 'Epithelial Cells', 'Humans', 'Loss of Heterozygosity', 'Lymphoma', 'Mice', 'Mutation', 'Neoplasms', 'Nuclear Proteins', 'Polycomb Repressive Complex 1', 'Polycomb-Group Proteins', 'Proto-Oncogene Proteins c-myc', 'Repressor Proteins', 'T-Lymphocytes', 'Tumor Suppres... | 17,374,722 | [['B01.050'], ['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.029.530'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.590'], ['C0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
White spot syndrome virus isolates of tiger shrimp Penaeus monodon (Fabricious) in India are similar to exotic isolates as revealed by polymerase chain reaction and electron microscopy. | Microbiological analysis of samples collected from cases of white spot disease outbreaks in cultured shrimp in different farms located in three regions along East Coast of India viz. Chidambram (Tamil Nadu), Nellore (Andhra Pradesh) and Balasore (Orissa), revealed presence of Vibrio alginolyticus, Vibrio parahaemolytic... | ['Aeromonas', 'Animals', 'Base Sequence', 'DNA, Viral', 'India', 'Microscopy, Electron', 'Penaeidae', 'Polymerase Chain Reaction', 'Vibrio', 'Virus Diseases', 'White spot syndrome virus 1'] | 16,053,274 | [['B03.440.450.019.025'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.568'], ['Z01.252.245.393'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.050.500.131.365.190.660'], ['E05.393.620.500'], ['B03.440.450.900.859', 'B03.660.250.830.830'], ['C01.925'], ['B04.280.505.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Invasive aspergillosis in the recipients of liver retransplantation. | Retransplantation is a major risk factor for invasive aspergillosis in liver transplant recipients. However, the risk for invasive aspergillosis with time elapsed since retransplantation, clinical characteristics, and outcome of patients who develop this infection after retransplantation of the liver has not been defin... | ['Adolescent', 'Adult', 'Antifungal Agents', 'Aspergillosis', 'Humans', 'Liver Transplantation', 'Lung Diseases, Fungal', 'Male', 'Middle Aged', 'Postoperative Complications', 'Reoperation', 'Retrospective Studies', 'Risk Factors'] | 16,598,780 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.136'], ['C01.150.703.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['C01.150.703.534', 'C01.748.435', 'C08.381.472', 'C08.730.435'], ['M01.060.116.630'], ['C23.550.767'], ['E04.69... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Analysis of choroidal thickness in AP-ROP, threshold disease and ROP without laser photocoagulation]. | BACKGROUND: Enhanced depth imaging (EDI) and spectral domain optical coherence tomography (SD-OCT) provide high-definition cross-sectional images of the choroid. Information on alterations in choroidal thickness (CT) after laser photocoagulation (LC) in aggressive posterior retinopathy of prematurity (APROP) and thresh... | ['Child, Preschool', 'Choroid', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Laser Coagulation', 'Male', 'Reproducibility of Results', 'Retinopathy of Prematurity', 'Sensitivity and Specificity', 'Tomography, Optical Coherence', 'Treatment Outcome'] | 26,142,227 | [['M01.060.406.448'], ['A09.371.894.223'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E02.520.745.410', 'E02.594.530', 'E04.014.520.530', 'E04.350.750.410', 'E04.540.630.410'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['C11.768.836',... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Temporal and spatial expression of a fos-lacZ transgene in the developing nervous system. | A Fos-lacZ transgenic mouse has been described that accurately recapitulates both constitutive and inducible patterns of c-fos expression in adult mice. Here we describe the developmental expression of the transgene in the brain during the early postnatal period. On the day of birth, expression of the transgene is obse... | ['Animals', 'Brain', 'Gene Expression Regulation', 'Genes, fos', 'Mice', 'Mice, Transgenic', 'Time Factors'] | 1,334,194 | [['B01.050'], ['A08.186.211'], ['G05.308'], ['G05.360.340.024.340.375.500.791.330'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Scientific priorities for the BRAIN Initiative. | We present a summary of the scientific deliberations and major conclusions that arose from a workshop on the BRAIN Initiative. | ['Animals', 'Behavior', 'Brain', 'Humans', 'Neurons', 'Neurosciences', 'United States'] | 23,900,253 | [['B01.050'], ['F01.145'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675', 'A11.671'], ['H01.158.610'], ['Z01.107.567.875']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
[Indications and contraindications for surgical treatment of morbid obesity--the choice of operative method]. | Surgery for morbid obesity should be considered in case of failure of conservative treatment (diet, physical activity, psychotherapy, supportive medications). It is strongly recommended also for patients with significant concomitant diseases (e.g. cardiovascular, pulmonary etc) difficult to manage with traditional ther... | ['Adolescent', 'Adult', 'Body Mass Index', 'Choice Behavior', 'Contraindications', 'Female', 'Gastroplasty', 'Humans', 'Male', 'Middle Aged', 'Obesity, Morbid'] | 15,603,367 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['F02.463.785.373.346'], ['E02.208'], ['E02.650.500.062.750', 'E04.062.750', 'E04.210.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500.700', 'C23... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of parathyroid hormone on renin secretion. | The ability of parathyroid hormone (PTH) to increase renin secretion was investigated in pentobarbital-anesthetized dogs. An intravenous infusion of bovine PTH 1-34, at the dose of 0.028 microgram/kg-1 min-1 increased renin secretion by 149% (501 +/- 105 to 1249 +/- 309 ng hr-1 min-1); renin secretion returned to contr... | ['Animals', 'Dogs', 'Kidney', 'Parathyroid Hormone', 'Phosphates', 'Renin', 'Sodium'] | 6,342,000 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A05.810.453'], ['D06.472.699.590', 'D12.644.548.587'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['D08.811.277.656.074.500.780', 'D08.811.277.656.300.048.780', 'D08.811.277.656.837.750'], ['D01.268.549.750', 'D01.268.557.650',... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dexamethasone blocking effects on mu- and delta-opioid-induced seizures involves kappa-opioid activity in the rabbit. | Previous data indicate that intracerebroventricular administration of agonists for mu- and delta-opioid receptors induces limbic seizures in rats, but no data are reported in rabbits. We found that the mu- and delta-opioid peptides [D-Ala(2)-N,Me-Phe(4)-Gly(5)-ol]enkephalin (DAMGO), beta-endorphin and deltorphin II, in... | ['Analgesics, Opioid', 'Animals', 'Dexamethasone', 'Electroencephalography', 'Enkephalin, Ala(2)-MePhe(4)-Gly(5)-', 'Glucocorticoids', 'Oligopeptides', 'Rabbits', 'Receptors, Opioid, delta', 'Receptors, Opioid, kappa', 'Receptors, Opioid, mu', 'Seizures', 'beta-Endorphin'] | 11,287,802 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['E01.370.376.300', 'E01.370.405.245'], ['D12.644.400.575.281.075', 'D12.776.631.650.575.281.075'], ['D06.472.040.543', 'D27... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Management strategy for fetal tachycardia. | OBJECTIVE: To develop a management strategy for fetal tachycardia.METHODS: Forty-four fetuses (20-40 weeks' gestation) with nonsinus tachycardia were divided into three groups based on duration of tachycardia and degree of heart failure. Fetuses with intermittent tachycardia were treated expectantly. Fetuses with susta... | ['Anti-Arrhythmia Agents', 'Echocardiography', 'Female', 'Fetal Diseases', 'Gestational Age', 'Heart Failure', 'Humans', 'Infant, Newborn', 'Pregnancy', 'Tachycardia', 'Ultrasonography, Prenatal'] | 11,004,362 | [['D27.505.954.411.097'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C13.703.277', 'C16.300'], ['G07.345.500.325.235.968', 'G08.686.320'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769'], ['C14.280.067.845', 'C14.280.123.875', 'C23... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spatial and temporal profiles of cytokinin biosynthesis and accumulation in developing caryopses of maize. | BACKGROUND AND AIMS: Cytokinins are a major group of plant hormones and are associated with various developmental processes. Developing caryopses of maize have high levels of cytokinins, but little is known about their spatial and temporal distribution. The localization and quantification of cytokinins was investigated... | ['Cytokinins', 'Endosperm', 'Fruit', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Plant', 'In Situ Hybridization', 'Ovule', 'Plant Proteins', 'RNA, Messenger', 'Seeds', 'Time Factors', 'Zea mays'] | 21,169,292 | [['D03.633.100.759.138.525'], ['A18.024.500.750.666'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.393.332'], ['G05.308.310'], ['G05.308.375'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['A18.024.249.500.249.249'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Antimicrobial Efficacy of Mixtures of Nanosilver and Zinc Oxide Eugenol against Enterococcus faecalis. | AIM: This study aimed to assess the antimicrobial efficacy of 0, 0.5, 2, and 5 wt% nanosilver in conjunction with zinc oxide eugenol (ZOE) against Enterococcus faecalis.MATERIALS AND METHODS: Nanosilver in 0.5, 2, and 5 wt% concentrations was added to ZOE and the antibacterial activity of the mixtures on E. faecalis wa... | ['Anti-Bacterial Agents', 'Disk Diffusion Antimicrobial Tests', 'Dose-Response Relationship, Drug', 'Drug Therapy, Combination', 'Enterococcus faecalis', 'Eugenol', 'Metal Nanoparticles', 'Silver Compounds', 'Zinc Oxide'] | 28,258,260 | [['D27.505.954.122.085'], ['E01.370.225.875.595.399', 'E05.200.875.595.399'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.310'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['D02.241.223.200.054.500'], ['J01.637.512.600.500'], ['D01.847'], ['D01.650.550.975', 'D01.975.975']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Stellate Ganglion Block for Painful Congenital Venous Malformation of the Arm. | Stellate ganglion block is an established intervention used in pain management settings. Its use in the treatment of congenital venous malformations (VM) of the upper limb has never been described. We present a case of ultrasound-guided stellate ganglion block for a patient who derived excellent relief from pain uncont... | ['Anesthetics, Local', 'Arm', 'Arteriovenous Malformations', 'Autonomic Nerve Block', 'Bupivacaine', 'Humans', 'Male', 'Pain Management', 'Stellate Ganglion', 'Young Adult'] | 25,858,167 | [['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['A01.378.800.075'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['E03.155.086.711.299', 'E04.525.210.550.500'], ['D02.065.199.239', 'D02.092.146.113.239'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.745',... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gold-Catalyzed Intramolecular Tandem Cyclization of Indole-Ynamides: Diastereoselective Synthesis of Spirocyclic Pyrrolidinoindolines. | A gold-catalyzed intramolecular tandem cyclization of indole-ynamide affords tetracyclic spirocyclic pyrrolidinoindoline bearing an all-carbon quaternary stereocentre in a single step; however, when the reaction was carried out in the presence of BF3 ?Et2 O, the corresponding tricyclic spirocyclic pyrrolidinoindoline-b... | ['Alkaloids', 'Catalysis', 'Cyclization', 'Gold', 'Indoles', 'Spiro Compounds', 'Stereoisomerism'] | 26,374,716 | [['D03.132'], ['G02.130'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D03.633.100.473'], ['D02.455.426.779', 'D04.711'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Pioneer Schools of Occupation: Reflections for Current Practice. | The Pioneer Schools of Occupation: Can They Teach Us Anything Today? This study reviews the development of the pioneer schools of occupation and their curriculum or program design between 1906 and 1923. The purposes are to document the existence of the schools, to explore the issues in establishing the schools, and to ... | ['Curriculum', 'Education, Professional', 'Health Occupations', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Occupational Therapy', 'Schools', 'Societies', 'United States'] | 30,074,856 | [['I02.158'], ['I02.358'], ['H02'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['I02.783', 'J03.832'], ['N03.540.828'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Immunization with rough mutants of Salmonella minnesota: initial studies in human subjects. | Vaccines prepared from unheated and boiled, acetone-precipitated Salmonella minnesota R595 (Re chemotype mutant) were administered subcutaneously to 122 healthy volunteers. Titers of antibody to Re lipopolysaccharide, the basal core structure of endotoxin, as measured by indirect hemagglutination, rose in a dose-respon... | ['Adolescent', 'Adult', 'Animals', 'Antibodies, Bacterial', 'Bacterial Vaccines', 'Fever', 'Humans', 'Immunity', 'Immunization', 'Immunization, Secondary', 'Klebsiella pneumoniae', 'Lipopolysaccharides', 'Male', 'Mice', 'Mice, Inbred Strains', 'Middle Aged', 'Mutation', 'Proteus', 'Rabbits', 'Salmonella', 'Salmonella t... | 3,042,872 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D20.215.894.135'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.78... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subsequent malignancies in patients treated with 131-iodine for thyroid cancer. | I-131 was administered to 298 patients with thyroid cancer, and there has been a follow-up of at least two years. Follow-up periods were: 2.5 to 30 years (median 14.5) in living patients, 2.5 to 15 years (median 5.5) in patients dead of tumour greater than or equal to 2 years after first treatment and 2.5 to 23 years (... | ['Adenocarcinoma', 'Adolescent', 'Aged', 'Aged, 80 and over', 'Bone Marrow', 'Carcinoma, Papillary', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Iodine Radioisotopes', 'Leukemia, Radiation-Induced', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Neoplasms, Radiation-Induced', 'Radiotherapy', 'Radiotherap... | 1,621,212 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A15.382.216'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prenyltransferase; determination of the binding mechanism and individual kinetic constants for farnesylpyrophosphate synthetase by rapid quench and isotope partitioning experiments. | The 1'-4 condensation reaction catalyzed by farnesylpyrophosphate synthetase was examined by using rapid quench and isotope partitioning experiments. E.Mg2+-isopentyl-PP (PP = pyrophosphate) is not catalytically competent, as evidenced by failure to trap the complex with Mg2+-geranyl-PP at concentrations as high as 3.2... | ['Alkenes', 'Animals', 'Binding Sites', 'Birds', 'Carbon Radioisotopes', 'Dimethylallyltranstransferase', 'Hemiterpenes', 'Kinetics', 'Liver', 'Magnesium', 'Mathematics', 'Organophosphorus Compounds', 'Protein Binding', 'Radioisotope Dilution Technique', 'Time Factors', 'Transferases'] | 7,013,805 | [['D02.455.326.271'], ['B01.050'], ['G02.111.570.120'], ['B01.050.150.900.248'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D08.811.913.225.400'], ['D02.455.849.486'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['H01.548'], ['D02.705'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional properties of sarcoplasmic reticulum Ca(2+)-ATPase after proteolytic cleavage at Leu119-Lys120, close to the A-domain. | By measuring the phosphorylation levels of individual proteolytic fragments of SERCA1a separated by electrophoresis after their phosphorylation, we were able to study the catalytic properties of a p95C-p14N complex arising from SERCA1a cleavage by proteinase K between Leu(119) and Lys(120), in the loop linking the A-do... | ['Animals', 'Calcium', 'Calcium-Transporting ATPases', 'Catalytic Domain', 'Endopeptidases', 'Hydrolysis', 'Leucine', 'Lysine', 'Models, Molecular', 'Phosphorylation', 'Sarcoplasmic Reticulum Calcium-Transporting ATPases', 'Structure-Activity Relationship'] | 14,672,956 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D08.811.277.656.300'], ['G02.380'], ['D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enantioselective determination of oxprenolol in human plasma using dialysis coupled on-line to reversed-phase chiral liquid chromatography. | A fully automated method for the determination of the enantiomers of oxprenolol in human plasma was developed, involving dialysis through a cellulose acetate membrane, clean-up and enrichment of the dialysate on a short precolumn and subsequent chiral liquid chromatographic (LC) analysis. All sample handling operations... | ['Adrenergic beta-Antagonists', 'Autoanalysis', 'Chromatography, Liquid', 'Dialysis', 'Humans', 'Linear Models', 'Molecular Structure', 'Online Systems', 'Oxprenolol', 'Reproducibility of Results', 'Stereoisomerism'] | 9,226,565 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['E05.059'], ['E05.196.181.400'], ['E05.196.353', 'G02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Immunoregulation of Dendritic Cell Subsets by Inhibitory Receptors in Urothelial Cancer. | Blockade of inhibitory receptors (IRs) overexpressed by T cells can activate antitumor immune responses, resulting in the most promising therapeutic approaches, particularly in bladder cancer, currently able to extend patient survival. Thanks to their ability to cross-present antigens to T cells, dendritic cells (DCs) ... | ['Biomarkers, Tumor', 'Case-Control Studies', 'Dendritic Cells', 'Hepatitis A Virus Cellular Receptor 2', 'Humans', 'Phenotype', 'Receptors, Immunologic', 'Signal Transduction', 'Tumor Microenvironment', 'Up-Regulation', 'Urinary Bladder Neoplasms', 'Urothelium'] | 28,277,277 | [['D23.101.140'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D12.776.395.550.479', 'D12.776.465.798', 'D12.776.543.550.437', 'D12.776.543.750.830.219'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.695'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of mayonnaise pH and storage temperature on the behavior of Listeria monocytogenes in ham salad and potato salad. | This study examined and modeled the behavior of Listeria monocytogenes in ham salad and potato salad as affected by the pH of mayonnaise and storage temperature. An eight-strain cocktail of L. monocytogenes was inoculated on the surface of diced cooked ham or potato. The inoculated ham or potato was then mixed with reg... | ['Animals', 'Colony Count, Microbial', 'Food Contamination', 'Food Preservation', 'Humans', 'Hydrogen-Ion Concentration', 'Listeria monocytogenes', 'Meat Products', 'Solanum tuberosum', 'Swine', 'Temperature'] | 21,132,970 | [['B01.050'], ['E01.370.225.875.220', 'E05.200.875.220'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['J01.576.423.850.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'], ['G07.203.300.600.500... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Direct 31P imaging in human limb and brain. | OBJECTIVE: This article describes two methods for direct imaging of the 31P-metabolites phosphocreatine (PCr) and inorganic phosphate (Pi) and their application in human brain and muscle.MATERIALS AND METHODS: All studies were performed on a 1.5 T whole-body GE Signa scanner, using bird cage resonators double-tuned to ... | ['Aged', 'Aged, 80 and over', 'Brain', 'Brain Neoplasms', 'Humans', 'Leg', 'Magnetic Resonance Spectroscopy', 'Middle Aged', 'Models, Structural', 'Muscles', 'Phosphates', 'Phosphocreatine', 'Physical Exertion'] | 8,370,818 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['E05.196.867.519'], ['M01.060.116.630'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['A02.633', 'A10.690'], ['D01.029... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
[Isolation and identification of Gardnerella vaginalis]. | Thirty-four strains of Gardnerella vaginalis were studied. They were isolated from non specific vaginitis. A presumptive identification can be based on colonial morphology, Gram stain characteristics, negative catalase and oxidase test. The differentiation of Gardnerella vaginalis from other negative catalase coccobaci... | ['Actinomyces', 'Bifidobacterium', 'Diagnosis, Differential', 'Female', 'Gardnerella vaginalis', 'Haemophilus', 'Humans', 'Lactobacillus acidophilus', 'Leukorrhea', 'Vaginal Smears', 'Vaginitis'] | 3,931,038 | [['B03.510.024.049.050.050', 'B03.510.460.400.400.049.049.178'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['E01.171'], ['B03.510.024.400.800'], ['B03.440.450.600.450', 'B03.660.250.550.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475.100', 'B03.510.460.400.410.475.475.100', 'B03.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of mechanical grinding of Sphagnum on the structure and physiological state of bacterial communities]. | The microcosm method was used to demonstrate an increase in bacterial numbers and drastic changes in the taxonomic structure of saprotrophic bacteria as a result of mechanical grinding of Sphagnum moss. Ekkrisotrophic agrobacteria predominant in untreated moss were replaced by hydrolytic bacteria. Molecular biological ... | ['Biodiversity', 'Carbon', 'Microbial Consortia', 'Nitrogen', 'Oxalobacteraceae', 'Soil Microbiology', 'Sphagnopsida', 'Streptomyces'] | 25,941,721 | [['G16.500.275.157.049', 'N06.230.124.049'], ['D01.268.150'], ['G06.591.750', 'G16.500.275.157.049.100.500.750', 'N06.230.124.049.100.500.500'], ['D01.268.604', 'D01.362.625'], ['B03.440.400.425.587', 'B03.660.075.090.883'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['B01.650.940.800.575.137.750'], ['B03.300.390.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Hollow-fiber-supported liquid membrane microextraction of amlodipine and atorvastatin. | A simple, environmentally friendly, and efficient method, based on hollow-fiber-supported liquid membrane microextraction, followed by high-performance liquid chromatography has been developed for the extraction and determination of amlodipine (AML) and atorvastatin (ATO) in water and urine samples. The AML in two-phas... | ['Amlodipine', 'Anticholesteremic Agents', 'Antihypertensive Agents', 'Atorvastatin', 'Chromatography, High Pressure Liquid', 'Heptanoic Acids', 'Humans', 'Liquid Phase Microextraction', 'Pyrroles', 'Solid Phase Microextraction', 'Water Pollutants, Chemical'] | 24,833,551 | [['D03.383.725.203.065'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D27.505.954.411.162'], ['D03.383.129.578.075', 'D10.251.450.200'], ['E05.196.181.400.300'], ['D10.251.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.155.650.500'], ['D03.383.129.578'], ['E05.196.155.800.500'], ['D27.8... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Collusion in doctor-patient communication about imminent death: an ethnographic study. | OBJECTIVE: To discover and explore the factors that result in the "false optimism about recovery" observed in patients with small cell lung cancer.DESIGN: A qualitative observational (ethnographic) study in 2 stages over 4 years.SETTING: Lung diseases ward and outpatient clinic in a university hospital in the Netherlan... | ['Aged', 'Attitude to Death', 'Carcinoma, Small Cell', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Netherlands', 'Physician-Patient Relations', 'Prognosis', 'Prospective Studies', 'Qualitative Research', 'Right to Die', 'Truth Disclosure'] | 11,290,678 | [['M01.060.116.100'], ['F01.100.125', 'N05.300.125'], ['C04.557.470.200.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['Z01.542.651'], ['F01.829.401.650.675', 'N05.300.660.625'], ['E01.789'], ['E05.318.372.500.750.625', 'N05.715.360.3... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Fourth ventricular CART peptide induces c-fos in the area postrema and nucleus of the solitary tract via a CRF-receptor dependent mechanism. | Cocaine-and amphetamine-regulated transcript peptides (CARTp) suppress gastric emptying and nutritional intake following 4th icv administration. Whereas, the CARTp inhibition of gastric emptying was blocked by pre-treatment with a non-selective corticotropin releasing factor (CRF) antagonist, sucrose drinking was not, ... | ['Animals', 'Area Postrema', 'Corticotropin-Releasing Hormone', 'Eating', 'Fourth Ventricle', 'Gastrointestinal Tract', 'Hypothalamus', 'Male', 'Mesencephalon', 'Nerve Tissue Proteins', 'Neurons', 'Peptide Fragments', 'Proto-Oncogene Proteins c-fos', 'Rats, Sprague-Dawley', 'Receptors, Corticotropin-Releasing Hormone',... | 26,475,505 | [['B01.050'], ['A06.688.178.500', 'A08.186.211.132.810.591.500.286', 'A08.713.049.500'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['G07.203.650.283', 'G10.261.330'], ['A08.186.211.140.500'], ['A03.556'], ['A08.186.211.180.497', 'A08.186.211.200.31... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of parturition and lactation on blood and milk cell concentrations, corticosteroids, and neutrophil phagocytosis in the cow. | Blood differential leukocytes, erythrocytes, milk somatic cells, and neutrophil phagocytosis in 14 Holstein-Friesian cows were measured at 2-day intervals for 2 weeks before parturition, on the day of parturition, on postpartum days 1,2,5,10,15, and 30, and at monthly intervals throughout lactation. Circulating cortico... | ['Adrenal Cortex Hormones', 'Animals', 'Blood Cell Count', 'Cattle', 'Erythrocyte Count', 'Female', 'Labor, Obstetric', 'Lactation', 'Leukocyte Count', 'Mastitis, Bovine', 'Milk', 'Neutrophils', 'Phagocytosis', 'Pregnancy'] | 984,546 | [['D06.472.040'], ['B01.050'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.33... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Preventive services in a health maintenance organization: how well do pediatricians screen and educate adolescent patients? | OBJECTIVE: To determine whether pediatricians in managed care settings adhere to national guidelines concerning the provision of clinical preventive services.DESIGN: Surveys were mailed between September 1996 and April 1997 to all pediatricians practicing in a California group-model health maintenance organization. The... | ['Adolescent', 'Adolescent Behavior', 'Adolescent Health Services', 'California', 'Data Collection', 'Health Maintenance Organizations', 'Humans', 'Patient Education as Topic', 'Pediatrics', "Practice Patterns, Physicians'", 'Preventive Health Services', 'Risk-Taking'] | 10,665,605 | [['M01.060.057'], ['F01.145.022'], ['N02.421.044'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Influence of chlorthalidone on the pharmacokinetics and pharmacodynamics of Org 10172 (Lomoparan), a low molecular weight heparinoid, in healthy volunteers. | The influence of chlorthalidone (100 mg PO) on the pharmacokinetics and pharmacodynamics of Org 10172 (IV bolus injection of 3250 anti-Xa units), a low molecular weight heparinoid, was studied in six healthy male volunteers using an open randomized two-way crossover design. Chlorthalidone produced a slight decrease in ... | ['Adult', 'Blood Coagulation Tests', 'Chlorthalidone', 'Chondroitin Sulfates', 'Dermatan Sulfate', 'Drug Interactions', 'Glycosaminoglycans', 'Heparinoids', 'Heparitin Sulfate', 'Humans', 'Injections, Intravenous', 'Male', 'Metabolic Clearance Rate'] | 1,716,644 | [['M01.060.116'], ['E01.370.225.625.115', 'E05.200.625.115'], ['D02.065.884.365', 'D02.455.426.559.389.134.500', 'D02.478.600.500', 'D02.522.223.500', 'D02.886.590.700.365', 'D03.633.100.513.750.500'], ['D09.698.373.200.300'], ['D09.698.373.200.380'], ['G07.690.773.968'], ['D09.698.373'], ['D09.698.373.400.320'], ['D09... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of a Schiff base copper complex compound as potent anticancer molecule with multiple targets of action. | Copper is a biologically relevant metal as it is associated with various biomolecules related to essential physiological activities. Anticancer compounds with copper as a metal center is hypothesized to be less toxic and more potent. In the present study we have tested the efficacy of a family of Schiff base copper com... | ['Animals', 'Antineoplastic Agents', 'Antioxidants', 'Apoptosis', 'Breast Neoplasms', 'Cell Line, Tumor', 'Copper', 'Female', 'HEK293 Cells', 'Humans', 'Molecular Targeted Therapy', 'Organometallic Compounds', 'Rats', 'Rats, Mutant Strains', 'Schiff Bases', 'Structure-Activity Relationship'] | 20,797,395 | [['B01.050'], ['D27.505.954.248'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin. | Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins constitute a major superfamily of pore-forming proteins that act as bacterial virulence factors and effectors in immune defence. Upon binding to the membrane, they convert from the soluble monomeric form to oligomeric, membrane-insert... | ['Cell Membrane', 'Cholesterol', 'Computer Systems', 'Cryoelectron Microscopy', 'Diffusion', 'Disulfides', 'Hemolysin Proteins', 'Kinetics', 'Microscopy, Atomic Force', 'Models, Molecular', 'Negative Staining', 'Perforin', 'Pore Forming Cytotoxic Proteins', 'Protein Multimerization'] | 25,457,051 | [['A11.284.149'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['L01.224.230'], ['E01.370.350.515.402.150', 'E05.595.402.150'], ['G01.202', 'G02.196'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D12.776.543.695.444'], ['G01.374.661', 'G02.111.490'], ['E01.370.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reconstruction of bony mandibular and maxillary defects with one single transfer of a free fibula osteocutaneous flap. | One-stage bone reconstruction of both the maxilla and the mandible with a single bone transfer is unusual in microsurgery. The authors report and describe the surgical technique of an original one-stage bone reconstruction of the maxilla and the mandible in a defect caused by a gunshot injury. The reconstruction was pe... | ['Adult', 'Bone Transplantation', 'Fractures, Bone', 'Humans', 'Male', 'Mandibular Injuries', 'Maxilla', 'Reconstructive Surgical Procedures', 'Suicide, Attempted', 'Surgical Flaps', 'Tomography, X-Ray Computed', 'Wounds, Gunshot'] | 17,658,304 | [['M01.060.116'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.900.300.284.500.500', 'C26.915.300.425.500.500'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['E04.680'], ['F01.145.126.980.875.600', 'I01.880.735.856.600'], ['A10.850.71... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice. | Multiple sclerosis (MS) is an inflammatory disease in which myelin in the spinal cord is damaged. C-C chemokine receptor type 5 (CCR5) is implicated in immune cell migration and cytokine release in central nervous system (CNS). We investigated whether CCR5 plays a role in MS progression using a murine model, experiment... | ['Animals', 'Encephalomyelitis, Autoimmune, Experimental', 'Humans', 'Jurkat Cells', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Receptors, CCR5', 'Spinal Cord'] | 26,985,768 | [['B01.050'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567.569.440'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.52... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Services for children and adolescents with autism spectrum disorders: payment issues. | Primary care physicians have an important role in assuring that children with autism are identified as early as possible and have a medical home providing appropriate care and care coordination. Understanding efficient methods of care and modifying practice habits to minimize services not currently supported by procedu... | ['Adolescent', 'Autistic Disorder', 'Child', 'Child Health Services', 'Current Procedural Terminology', 'Humans', 'Insurance Claim Reporting', "Physician's Role", 'Primary Health Care', 'Reimbursement Mechanisms'] | 19,213,294 | [['M01.060.057'], ['F03.625.164.113.500'], ['M01.060.406'], ['N02.421.143.130'], ['L01.453.245.945.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.210'], ['F01.829.316.616.625.600'], ['N04.590.233.727'], ['N03.219.521.710.305']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Expression analysis of calcium-dependent protein kinase gene family during reproductive development and abiotic stress conditions in rice (Oryza sativa L. ssp. indica). | Calcium-dependent protein kinases (CDPKs) are important sensors of Ca(+2) flux in plants, which control plant development and responses by regulating downstream components of calcium signaling pathways. Availability of the whole genome sequence and microarray platform allows investigation of genome-wide organization an... | ['Chromosomes, Plant', 'Gene Expression Profiling', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genome, Plant', 'Models, Biological', 'Oligonucleotide Array Sequence Analysis', 'Oryza', 'Phylogeny', 'Protein Kinases', 'Seeds', 'Species Specificity'] | 17,636,330 | [['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['E05.393.332'], ['G05.308.320'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.365'], ['E05.599.395'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['B01.650.940.800.575.912.250.822.616'], ['G05.697', ... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Lymphocyte response to phytohemagglutinin in atopic dermatitis. | Studies of patients with atopic dermatitis (AD) have demonstrated several clinical and laboratory indications of immunity defects, but with frequently contradictory results. We have recently shown that many patients with negative cutaneous delayed type hypersensitivity to candidin and streptokinase-streptodornase may h... | ['Adolescent', 'Adult', 'Aged', 'Cells, Cultured', 'Child', 'Dermatitis, Atopic', 'Humans', 'Immunoglobulin E', 'In Vitro Techniques', 'Lymphocyte Activation', 'Middle Aged', 'Phytohemagglutinins'] | 533,287 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. | We describe herein the metabolic fate of cardioactive 1,3-benzodioxolyl N-acylhydrazone prototype LASSBio-294 (4) and the structural identification of its major phase I metabolite from rat liver microsomal assays. Our results confirmed the hard-metabolic character of N-acylhydrazone (NAH) framework of LASSBio-294 (4). ... | ['Animals', 'Biotransformation', 'Catalytic Domain', 'Chromatography, High Pressure Liquid', 'Chromatography, Liquid', 'Cytochrome P-450 CYP1A2', 'Heart', 'Humans', 'Hydrazones', 'Male', 'Mass Spectrometry', 'Microsomes, Liver', 'Models, Molecular', 'Rats', 'Rats, Wistar', 'Recombinant Proteins', 'Thiophenes'] | 21,144,625 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.181.400.300'], ['E05.196.181.400'], ['D08.244.453.005.443', 'D08.244.453.100.750', 'D08.811.682.690.708.170.010.443', 'D08.811.682.690.708.170.020.750', 'D12.776.422.220.453.010.443', 'D12.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Innovative programming in school mental health. Search for a methodology. | Entering a system it often regarded as the most difficult aspect of consultation, especially when entry is initiated by the consultant. Issues involved in seeking entry into a school system are considered from the perspective of a university-based consultant interested in developing, delivering, and evaluating innovati... | ['Attitude', 'Delivery of Health Care', 'Fees and Charges', 'Interprofessional Relations', 'Mental Health', 'Persuasive Communication', 'Referral and Consultation', 'School Health Services', 'Telephone'] | 872,669 | [['F01.100'], ['N04.590.374', 'N05.300'], ['N03.219.442'], ['F01.829.401.205'], ['F02.418', 'N01.400.500'], ['L01.143.762'], ['N04.452.758.849'], ['N02.421.726.809'], ['L01.178.847.698']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Computed tomography angiography of a congenital extrahepatic splenocaval shunt in a foal. | Congenital portosystemic shunts in foals are rare and only a small number of cases have been described. Detailed description of the course of the shunt is lacking in earlier reports. This is the first detailed description of a computed tomography angiography (CTA) displaying an extra-hepatic splenocaval shunt. A 1-mont... | ['Animals', 'Computed Tomography Angiography', 'Fatal Outcome', 'Horse Diseases', 'Horses', 'Male', 'Portal System'] | 31,412,901 | [['B01.050'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.825.810.810.499'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C22.488'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prognostic factors influencing prostate cancer-specific survival in non-castrate patients with metastatic prostate cancer. | BACKGROUND: In non-castrate prostate cancer (PCa), the prognostic value of the number of metastases on prostate cancer-specific survival (PCSS) is not well studied.METHODS: We retrospectively analyzed the medical records of 1,206 patients, referred for radiotherapy of the prostate (bed) following diagnosis of PCa. Dist... | ['Adult', 'Aged', 'Androgen Antagonists', 'Antineoplastic Agents, Hormonal', 'Bone Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Orchiectomy', 'Prognosis', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prostatic Neoplasms', 'Radiotherapy', 'Retrospective Studies', 'Surviv... | 24,395,565 | [['M01.060.116'], ['M01.060.116.100'], ['D06.347.065', 'D27.505.696.399.450.065'], ['D27.505.954.248.169'], ['C04.588.149', 'C05.116.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['E04.270.282.679', 'E04.950.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development and testing of a scale to assess physician attitudes about handheld computers with decision support. | OBJECTIVE: The authors developed and evaluated a rating scale, the Attitudes toward Handheld Decision Support Software Scale (H-DSS), to assess physician attitudes about handheld decision support systems.DESIGN: The authors conducted a prospective assessment of psychometric characteristics of the H-DSS including reliab... | ['Analysis of Variance', 'Attitude of Health Personnel', 'Attitude to Computers', 'Computers, Handheld', 'Decision Support Systems, Clinical', 'Evaluation Studies as Topic', 'Humans', 'Physicians', 'Psychometrics', 'Reproducibility of Results'] | 16,799,120 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.100.050', 'N05.300.100'], ['F01.100.100'], ['L01.224.230.260.550.500'], ['L01.313.500.750.300.190'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.810', 'N02.360.810'], ['F04.711.780'], ['E05.318.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Successful endoscopic transpapillary management of intrahepatic pancreatic pseudocyst. | CONTEXT: Intrahepatic pancreatic pseudocyst extension is a rare but complex clinical entity requiring multimodality approach for management. There is no consensus regarding the optimal strategy for the treatment of intrahepatic pancreatic pseudocyst and the literature is limited to a few case reports. Most of the publi... | ['Cholangiopancreatography, Endoscopic Retrograde', 'Drainage', 'Endoscopy', 'Humans', 'Liver', 'Male', 'Middle Aged', 'Pancreatic Pseudocyst', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 20,065,551 | [['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['E02.309', 'E04.237'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['M01.060.116.630'], ['C04.182.640.692', 'C06.689... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Valuing Preferences for the Process and Outcomes of Clinical Genetics Services: A Pilot Study. | BACKGROUND: Understanding preferences for the process and outcomes of clinical genetics services (CGS) is a first step to developing these services appropriately.AIM: The aim of this study was to quantify the relative importance of attributes defining the process of service delivery and the patient outcomes of CGS.METH... | ['Choice Behavior', 'Decision Making', 'Genetic Services', 'Health Services Research', 'Humans', 'Internet', 'Outcome and Process Assessment, Health Care', 'Patient Preference', 'Pilot Projects', 'State Medicine', 'Surveys and Questionnaires', 'United Kingdom'] | 26,085,127 | [['F02.463.785.373.346'], ['F02.463.785.373'], ['N02.421.308'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['N04.761.559', 'N05.715.360.575'], ['F01.100.150.750.625.500', 'F01.145.488.887.625.500', 'N04.452.822.700.500', 'N05.300.150.800.... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Meta-analysis of facial affect recognition difficulties after traumatic brain injury. | OBJECTIVE: Difficulties in communication and social relationships present a formidable challenge for many people after traumatic brain injury (TBI). These difficulties are likely to be partially attributable to problems with emotion perception. Mounting evidence shows facial affect recognition to be particularly diffic... | ['Adult', 'Affect', 'Brain Injuries', 'Discrimination, Psychological', 'Facial Expression', 'Humans', 'Neuropsychological Tests', 'Pattern Recognition, Visual', 'Recognition, Psychology'] | 21,463,043 | [['M01.060.116'], ['F01.470.047'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['F02.463.593.257'], ['E01.370.600.225', 'F01.145.209.530.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.425.540.706']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment of recent lesions of the dorsoradial compartment of the metacarpophalangeal (MP) joint of the thumb. | Lesions of the dorsoradial compartment of the metacarpophalangeal joint of the thumb, are encountered more rarely than rupture of the internal collateral ligament and are considered a less serious or complex lesion. However, the alteration of the various structures, at the level of the metacarpophalangeal joint, produc... | ['Adult', 'Biomechanical Phenomena', 'Bone Nails', 'Female', 'Follow-Up Studies', 'Humans', 'Joint Instability', 'Male', 'Metacarpophalangeal Joint', 'Radiography', 'Range of Motion, Articular', 'Thumb', 'Treatment Outcome'] | 9,336,621 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['A02.835.583.405.500'], ['E01.370.350... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Energetics and conformational changes upon complexation of a phenothiazine drug with human serum albumin. | The interactions and complexation process of the amphiphilic phenothiazine fluphenazine hydrochloride with human serum albumin in aqueous buffered solutions of pH 3.0 and 7.4 have been examined by zeta-potential, isothermal titration calorimetry (ITC), UV-vis spectroscopy, and dynamic light scattering (DLS) techniques ... | ['Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Light', 'Phenothiazines', 'Protein Conformation', 'Scattering, Radiation', 'Serum Albumin', 'Spectrophotometry, Ultraviolet', 'Thermodynamics'] | 17,592,874 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02.886.369', 'D03.633.300.783'], ['G02.111.570.820.709'], ['E05.196.822', 'G01.867'], ['D12.776.034.841', 'D12.776.124.727'], ['E05.196.712.726.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The priming effect of glucose on insulin release does not involve redistribution of secretory granules within the pancreatic B-cell. | Short-term stimulation of the pancreatic B-cell with glucose produces a time-dependent potentiation of this cell, which markedly enhances the insulin response to a renewed stimulation with the hexose. To study if a redistribution of the B-cell secretory granules to a location close to the B-cell plasma membrane could u... | ['Animals', 'Cytoplasmic Granules', 'Glucose', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Male', 'Microscopy, Electron', 'Rats', 'Rats, Inbred Strains'] | 3,286,324 | [['B01.050'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['D09.947.875.359.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', 'A06.300.414'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.05... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Local anesthetics (LA). Adverse reactions from the use of LA (IV)]. | Most common and significant adverse reactions directly attributable to the administration of local anesthetics which occur in dental practice are discussed. Both most severe systemic reactions--uncommonly found--and local reactions--of lesser importance--are reviewed. Tolerance, subtoxic doses and general toxicity of t... | ['Anesthesia, Dental', 'Anesthetics, Local', 'Dose-Response Relationship, Drug', 'Drug Hypersensitivity', 'Humans', 'Resuscitation'] | 2,640,040 | [['E03.155.141', 'E06.045'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['G07.690.773.875', 'G07.690.936.500'], ['C20.543.206', 'C25.100.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.365.647']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anaerotignum faecicola sp. nov., isolated from human faeces. | A strictly anaerobic bacterium, designated as strain KGMB-03357T, was isolated from the faeces of a healthy Korean selected by Bundang Seoul National University based on health status. Cells of strain KGMB03357T are Gram-stain-positive, non-motile, non-spore-forming, and observed as straight or curved rods. The isolate... | ['Bacterial Typing Techniques', 'Base Composition', 'Clostridiales', 'DNA, Bacterial', 'Diaminopimelic Acid', 'Fatty Acids', 'Feces', 'Humans', 'Hydrogen-Ion Concentration', 'Microbiota', 'Peptidoglycan', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Seoul', 'Sequence Analysis, DNA', 'Temperature'] | 31,680,219 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['B03.353.625'], ['D13.444.308.212'], ['D02.241.081.337.699.250', 'D12.125.095.390'], ['D10.251'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['D09... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Distant metastasis of renal adenocarcinoma in nephrectomized cases. | In an analysis of the autopsy records of 1,828 patients with renal adenocarcinoma 424 nephrectomized and 1,404 nonnephrectomized cases were compared to explore the effect of nephrectomy on metastasis. Over-all, no significant difference was observed except for a high incidence of metastases to the brain and femur, and ... | ['Adenocarcinoma', 'Adolescent', 'Adult', 'Aged', 'Autopsy', 'Child', 'Female', 'Humans', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Nephrectomy', 'Prognosis'] | 7,087,014 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['M01.060.116... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Clostridium botulinum group I strain genotyping by 15-locus multilocus variable-number tandem-repeat analysis. | Clostridium botulinum is a taxonomic designation that encompasses a broad variety of spore-forming, Gram-positive bacteria producing the botulinum neurotoxin (BoNT). C. botulinum is the etiologic agent of botulism, a rare but severe neuroparalytic disease. Fine-resolution genetic characterization of C. botulinum isolat... | ['Botulism', 'Clostridium botulinum', 'Cluster Analysis', 'Food Microbiology', 'Genotype', 'Humans', 'Minisatellite Repeats', 'Molecular Epidemiology', 'Molecular Typing', 'Pathology, Molecular', 'Phylogeny', 'Polymorphism, Genetic'] | 22,012,011 | [['C01.150.252.410.222.151', 'C10.668.758.200', 'C10.720.150', 'C25.723.415.151'], ['B03.300.390.400.200.160', 'B03.353.625.375.500.160', 'B03.510.415.400.200.160'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Postprocedural low molecular weight heparin in patients at high risk of subacute stent thrombosis. | BACKGROUND: Subacute stent thrombosis (SAT) is a dramatic complication of percutaneous coronary stenting occurring in 0.4-20% of cases depending on several angiographic and clinical variables. The role of postprocedural low molecular weight heparin (LMWH) in preventing early events after high-risk PCI is not well estab... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Coronary Stenosis', 'Dalteparin', 'Female', 'Fibrinolytic Agents', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Postoperative Care', 'Retrospective Studies', 'Risk Factors', 'Stents', 'Thrombosis', 'Treatment Outcome'] | 15,321,055 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['D09.698.373.400.300.150'], ['D27.505.519.421.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Affine magnetic sorbents supported on coal ash microspheres for recombinant protein isolation]. | The results of the development and utilization of an affine magnetic sorbent with Ni2+ ions immobilized on coal ash microspheres are reported. The applicability of the material in the isolation of Histag proteins is demonstrated by examples of the recombinant green fluorescent protein from Clytia gregarium and the Ca2+... | ['Calcium', 'Chromatography, Affinity', 'Coal', 'Green Fluorescent Proteins', 'Magnetics', 'Microspheres', 'Nickel', 'Particle Size', 'Recombinant Proteins'] | 19,382,714 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.196.181.400.170'], ['D20.345.108', 'N06.230.132.258.108'], ['D12.776.532.265'], ['H01.671.493'], ['E07.565'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['G02.712'], ['D12.776.828']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Histologically confirmed intracranial germ cell tumors; an analysis of 62 patients in a single institute. | This study was undertaken to document the clinicopathologic characteristics of histologically verified, primary intracranial germ cell tumors (GCTs), determine treatment outcomes, and to identify prognostic factors. The records of 62 patients (45 males and 17 females) with a primary intracranial GCT were retrospectivel... | ['Adolescent', 'Adult', 'Biomarkers, Tumor', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Immunohistochemistry', 'Infant', 'Infant, Newborn', 'Kaplan-Meier Estimate', 'Korea', 'Male', 'Middle Aged', 'Neoplasms, Germ Cell and Embryonal', 'Prognosis', 'Retrospective Studies', 'Young Adult'] | 20,652,714 | [['M01.060.057'], ['M01.060.116'], ['D23.101.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Predicting Antigenicity of Influenza A Viruses Using biophysical ideas. | Antigenic variations of influenza A viruses are induced by genomic mutation in their trans-membrane protein HA1, eliciting viral escape from neutralization by antibodies generated in prior infections or vaccinations. Prediction of antigenic relationships among influenza viruses is useful for designing (or updating the ... | ['Amino Acid Sequence', 'Antigenic Variation', 'Antigens, Viral', 'Computational Biology', 'Hemagglutinin Glycoproteins, Influenza Virus', 'Humans', 'Influenza A virus', 'Influenza Vaccines', 'Influenza, Human', 'Models, Theoretical'] | 31,308,446 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G05.365.073', 'G12.500.249'], ['D23.050.327'], ['H01.158.273.180', 'L01.313.124'], ['D12.776.964.970.880.345.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Early detection of Alzheimer's disease: a new working memory paradigm. | OBJECTIVES: Early detection of Alzheimer's disease (AD) offers the chance to decelerate the patients' cognitive decline and to prolong a self-determined, independent life. Neuropsychological testing is one key approach to establish an early diagnosis. Whereas more global cognitive abilities can be preserved until furth... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Early Diagnosis', 'Female', 'Humans', 'Inhibition, Psychological', 'Male', 'Mass Screening', 'Memory Disorders', 'Memory, Short-Term', 'Neuropsychological Tests', 'Pilot Projects'] | 17,621,381 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E01.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.50... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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