Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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A PLCdelta1-binding protein, p122RhoGAP, is localized in focal adhesions. | We have investigated the cellular distribution of p122RhoGAP, a GTPase-activating protein of Rho small GTPase and an activator of phospholipase C-delta(1). Immunofluorescence studies demonstrated that endogenous p122 is localized at the tips of actin stress fibres and co-localizes with vinculin in normal rat kidney cel... | ['Animals', 'Binding Sites', 'Cell Adhesion', 'GTPase-Activating Proteins', 'Isoenzymes', 'Kidney', 'Models, Biological', 'Phospholipase C delta', 'Protein Binding', 'Rats', 'Type C Phospholipases', 'Vinculin'] | 15,506,980 | [['B01.050'], ['G02.111.570.120'], ['G04.022'], ['D12.644.360.325.150', 'D12.776.476.325.150'], ['D08.811.348', 'D12.776.800.300'], ['A05.810.453'], ['E05.599.395'], ['D08.811.277.352.640.700.700.562.625', 'D12.644.360.571.625', 'D12.776.476.556.625'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.649.313.992.635.505.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The oxidative refolding of hen lysozyme and its catalysis by protein disulfide isomerase. | The oxidative refolding of hen lysozyme has been studied by a variety of time-resolved biophysical methods in conjunction with analysis of folding intermediates using reverse-phase HPLC. In order to achieve this, refolding conditions were designed to reduce aggregation during the early stages of the folding reaction. A... | ['Animals', 'Catalysis', 'Chickens', 'Chromatography, High Pressure Liquid', 'Circular Dichroism', 'Disulfides', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Models, Chemical', 'Models, Molecular', 'Muramidase', 'Oxidation-Reduction', 'Protein Disulfide-Isomerases', 'Protein Folding', 'Spectrometry, Fluorescence', '... | 10,469,657 | [['B01.050'], ['G02.130'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.300'], ['E05.196.867.151'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['E05.599.495'], ['E05.599.595'], ['D08.811.277.450.642'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlated slow fluctuations in respiration, EEG, and BOLD fMRI. | Low-frequency temporal fluctuations of physiological signals (<0.1 Hz), such as the respiration and cardiac pulse rate, occur naturally during rest and have been shown to be correlated with blood-oxygenation-level-dependent (BOLD) signal fluctuation. Such physiological signal modulations have been considered as sources... | ['Adult', 'Biological Clocks', 'Brain', 'Brain Mapping', 'Electroencephalography', 'Female', 'Heart Rate', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Reproducibility of Results', 'Respiratory Rate', 'Sensitivity and Specificity', 'Statistics as Topic'] | 23,631,982 | [['M01.060.116'], ['G07.180.562.094'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E05.318.370.725', 'E05.337.85... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Piagetian conservation and response to cognitive therapy in attention deficit disordered children. | Cognitive therapy is often used in treating attention-deficit-disordered (ADD) children because of its purported ability to address this population's attentional deficits and behavioral difficulties and to create durable therapeutic effects. Nonetheless, research findings on these treatments have been inconsistent. Thi... | ['Attention', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child Development', 'Cognition Disorders', 'Concept Formation', 'Education, Special', 'Female', 'Humans', 'Male', 'Problem Solving'] | 3,667,738 | [['F02.830.104.214'], ['F03.625.094.150'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['F03.615.250'], ['F02.463.785.233'], ['I02.233.213'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.725', 'F02.463.785.810']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Protective Role of Glutathione against Peroxynitrite-Mediated DNA Damage During Acute Inflammation. | Inflammation is an immune response to protect against various types of infections. When unchecked, acute inflammation can be life-threatening, as seen with the current coronavirus pandemic. Strong oxidants, such as peroxynitrite produced by immune cells, are major mediators of the inflammation-associated pathogenesis. ... | ['Acute Disease', 'Animals', 'Betacoronavirus', 'COVID-19', 'Cattle', 'Coronavirus Infections', 'DNA', 'DNA Adducts', 'DNA Damage', 'Glutathione', 'HEK293 Cells', 'Humans', 'Inflammation', 'Mutagens', 'Pandemics', 'Peroxynitrous Acid', 'Pneumonia, Viral', 'SARS-CoV-2', 'Salmonella typhimurium'] | 32,894,672 | [['C23.550.291.125'], ['B01.050'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['B01.050.150.900.649.313.500.380.271'], ['C01.925.782.600.550.200'], ['D13.444.308'], ['D13.444.308.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structural changes of the carpal tunnel, median nerve and flexor tendons in MRI before and after endoscopic carpal tunnel release. | The purpose of this study is to investigate the structural changes of the carpal tunnel, median nerve, and flexor tendons in magnetic resonance imaging (MRI) before and after endoscopic carpal tunnel release (ECTR). We studied 36 hands undergoing ECTR. In MRI, the cross-sectional area of the carpal tunnel and the media... | ['Aged', 'Aged, 80 and over', 'Carpal Tunnel Syndrome', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Median Nerve', 'Middle Aged', 'Postoperative Care', 'Preoperative Care', 'Tendons', 'Wrist'] | 24,875,502 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.800.800.720.050.500'], ['M01.060.116.630'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E02.760.795', 'E0... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Causes of inadequate vision in drivers and their significance in traffic]. | From an analysis of the data of 462 automobile drivers with inadequate visual acuity it was established that the frequency of visits to the ophthalmologist by drivers with inadequate vision is determined less by age than by the cause of the visual deficiency. Here, considerable differences appear in the duration of ina... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Automobile Driving', 'Cataract', 'Disability Evaluation', 'Female', 'Glaucoma', 'Humans', 'Macular Degeneration', 'Male', 'Middle Aged', 'Refractive Errors', 'Vision Disorders', 'Visual Acuity'] | 3,573,652 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['I03.125'], ['C11.510.245'], ['E01.370.400'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439'], ['M01.060.116.630'], ['C11.744'], ['C10.597.751.941', 'C11.966', 'C23.888.592.763.941'], [... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Exogenous surfactant application in respiratory failure due to chronic obstructive pulmonary disease. | Recent results of basic research on regulation of surfactant secretion and surfactant physiology not only in the alveolus but also in peripheral small airways allow the conclusion that disorders in surfactant homeostasis may contribute to the pathophysiology of airway obstruction and hyperinflation. We therefore hypoth... | ['Aged', 'Biological Products', 'Female', 'Humans', 'Lung Diseases, Obstructive', 'Pulmonary Surfactants', 'Respiration', 'Respiratory Insufficiency', 'Smoking', 'Time Factors'] | 7,569,338 | [['M01.060.116.100'], ['D20.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495'], ['D27.505.954.796.600'], ['G09.772.705'], ['C08.618.846'], ['F01.145.805'], ['G01.910.857']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Variations of Runoff and Sediment Load in the Middle and Lower Reaches of the Yangtze River, China (1950-2013). | On the basis of monthly runoff series obtained in 1950-2013 and annual sediment load measured in 1956--2013 at five key hydrological stations in the middle and lower reaches of the Yangtze River basin, this study used the Mann-Kendall methods to identify trend and abrupt changes of runoff and sediment load in relation ... | ['Algorithms', 'China', 'Environmental Monitoring', 'Geologic Sediments', 'Rivers', 'Seasons'] | 27,479,591 | [['G17.035', 'L01.224.050'], ['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Scanning Electron Microscopy of Sand Flies of the Chagasi Series, Psychodopygus (Diptera: Psychodidae) Genus, Focusing on the Genitalia. | Males of cryptic or closely related species present great morphological variation in their genitalia, whereas females, such as those of the Chagasi Series of the Psychodopygus Mangabeira, 1941 genus, are more similar. Therefore, our aim was to study the fine structure of the male genitalia of five species of the Chagas... | ['Animals', 'Brazil', 'Genitalia, Male', 'Insect Vectors', 'Leishmaniasis, Cutaneous', 'Male', 'Psychodidae'] | 31,576,409 | [['B01.050'], ['Z01.107.757.176'], ['A05.360.444'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C01.920.813.400', 'C17.800.838.775.560.400'], ['B01.050.500.131.617.720.500.500.750.781']] | ['Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A simplified method for separate measurements of lung and chest wall mechanics in ventilator-treated patients. | BACKGROUND: Airway pressure measurements above the endotracheal tube will be distorted because of endotracheal tube resistance. To separate lung and chest wall compliance, esophageal pressure is conventionally measured with an air-filled balloon catheter, which is difficult to insert in unconscious patients. We have de... | ['Adult', 'Aged', 'Airway Resistance', 'Anesthesia', 'Compliance', 'Esophagus', 'Female', 'Humans', 'Intubation', 'Lung Compliance', 'Male', 'Middle Aged', 'Positive-Pressure Respiration', 'Pressure', 'Respiration, Artificial', 'Respiratory Mechanics', 'Thorax', 'Tidal Volume', 'Trachea'] | 10,081,537 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.386.700.050', 'G09.772.060'], ['E03.155'], ['G01.374.590.210'], ['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.585', 'E05.497'], ['E01.370.386.700.475', 'G09.772.540'], ['M01.060.116.630'], ['E02.041.625.790', 'E02.880.820.790'], ['G01.374.71... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intraoral vertical subcondylar osteotomy: a national survey. | The results of a national survey pertaining to the IVSO are presented and the findings are contrasted with the literature on the procedure. It was found that the IVSO is a popular procedure for mandibular setback, that the value of determining the mandibular divergence angle is equivocal, that the Stryker oscillating s... | ['Humans', 'Immobilization', 'Mandible', 'Mandibular Condyle', 'Osteotomy', 'Prognathism', 'Surgery, Oral', 'United States'] | 3,858,482 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.472'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['A02.835.232.781.324.502.632.600', 'A14.521.632.600'], ['E04.555.580'], ['C05.500.460.655', 'C05.500.607.655', 'C05.660.207.540.460.655', 'C07.320.440.655', 'C07.320.610.655', 'C07.650.500.460.655', 'C16.131.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
[Part of the matrix on the 5' side from codon in the E-segment is close to protein S26 on the human 80S ribosome]. | Positioning of mRNA on the 80S ribosome upstream the E site bound codon was studied using derivatives of nona- and dodecaribonucleotides containing the triplet UUU coding for Phe at the 3'-terminus, and a perfluorophenylazide cross-linker on either the first or the third nucleotide. Two sets of the mRNA analogues were ... | ['Codon', 'Electrophoresis, Gel, Two-Dimensional', 'Humans', 'RNA, Messenger', 'Ribosomal Proteins', 'Ribosomes'] | 15,612,591 | [['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['E05.196.401.250', 'E05.301.300.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.444.735.544'], ['D12.776.835'], ['A11.284.430.214.190.875.811']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The Freiburg Scarlet Fever Scheme, a guide for clinical practice in frequent occurrence of Streptococcus-A infections in schools and other community facilities according to paragraphs 44-48 of the Federal Infection Legislation]. | In the past years, the endemic occurrence of A-streptococcal infections in communal institutions for children and other reasons called for an increased number of activities to combat such diseases. In view of the multitude of different epidemiological situations, differentiated suggestions favouring a holistic strategy... | ['Adolescent', 'Child', 'Communicable Disease Control', 'Germany', 'Humans', 'Public Health', 'Scarlet Fever', 'Schools'] | 2,146,558 | [['M01.060.057'], ['M01.060.406'], ['N06.850.780.200'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['C01.150.252.410.890.823'], ['I02.783', 'J03.832']] | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
[Forms of histograms constructed from measurements of alpha-decay of 228Ra in Lindau (Germany) and neutron fluxes in Moscow change synchronously according to the local time]. | In joint experiments performed at Max Plank Institute of Aeronomy (Germany) and the Institute of Theoretical and Experimental Biophysics in Pushchino, the main manifestations of the phenomenon of macroscopic fluctuations were confirmed. An increased probability of the similarity in synchronous histograms in independent... | ['Alpha Particles', 'Neutrons', 'Radium', 'Statistical Distributions', 'Time'] | 11,605,368 | [['G01.750.750.055'], ['G01.249.660.250'], ['D01.268.271.770', 'D01.268.552.775', 'D01.268.556.775', 'D01.496.749.305.770', 'D01.552.539.745', 'D01.552.544.775'], ['E05.318.740.994', 'G17.820', 'N05.715.360.750.750', 'N06.850.520.830.994'], ['G01.910']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Replication of feline coronaviruses in peripheral blood monocytes. | Feline infectious peritonitis virus (FIPV) (Coronaviridae) causes the most lethal viral infection in cats: FIP. The related feline enteric coronavirus (FECV) causes mild enteritis. Why these feline coronaviruses manifest so differently in vivo is not known. In this study, infection kinetics (titres and antigen expressi... | ['Animals', 'Cat Diseases', 'Cats', 'Cells, Cultured', 'Coronavirus Infections', 'Coronavirus, Feline', 'Feline Infectious Peritonitis', 'Female', 'Male', 'Microscopy, Confocal', 'Monocytes', 'Viral Proteins', 'Virus Replication'] | 16,052,283 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A11.251'], ['C01.925.782.600.550.200'], ['B04.820.578.500.540.150.075.500.375'], ['C01.925.782.600.550.200.360', 'C22.180.440'], ['E01.370.350.515.395', 'E05.595.395'], ['A11.118.637.555.652', 'A11.148.580', 'A11.627.624', 'A11.733.547', 'A15... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Congenital hemangiopericytoma. | The clinicopathologic features of a case of congenital hemangiopericytoma are described and compared with those of previously reported cases. Features connotative of malignancy in adult or childhood hemangiopericytomas, such as high mitotic activity, increased cellularity, and tissue necrosis or hemorrhage, are frequen... | ['Hemangiopericytoma', 'Humans', 'Infant, Newborn', 'Neoplasm Regression, Spontaneous', 'Soft Tissue Neoplasms'] | 3,713,189 | [['C04.557.645.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C04.697.670', 'C23.550.727.670', 'G16.767.500'], ['C04.588.839']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The role of the spleen in the rejection and enhancement of renal allografts in the rat. | As rats were splenectomised up to 7 weeks before or at the time of receiving an (AS times August)F1 kidney allograft. Only 2 of 19 splenectomised recipients rejected their grafts within 12 days, and 14 of the 19 survived for more than 100 days. All 19 splenectomised recipients had a marked and often complete suppressio... | ['Animals', 'Antibody Formation', 'Chimera', 'Homozygote', 'Kidney Transplantation', 'Male', 'Rats', 'Spleen', 'Splenectomy', 'Time Factors', 'Transplantation Immunology', 'Transplantation, Homologous'] | 1,099,728 | [['B01.050'], ['G12.450.050.370.250'], ['B05.200'], ['G05.380.554'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['A10.549.700', 'A15.382.520.604.700'], ['E04.726'], ['G01.910.857'], ['G12.875'], ['E04.936.864']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An investigation of the evolutionary origin of reciprocal communication using simulated autonomous agents. | How does communication originates in a population of originally non-communicating individuals? Providing an answer to this question from a neo-Darwinian epistemological perspective is not a trivial task. The reason is that, for non-communicating agents, the capabilities of emitting signals and responding to them are bo... | ['Algorithms', 'Animals', 'Auditory Perception', 'Behavior, Animal', 'Biological Evolution', 'Communication', 'Computer Simulation', 'Humans', 'Mathematical Concepts', 'Models, Theoretical', 'Robotics', 'Social Behavior', 'Vocalization, Animal'] | 19,730,879 | [['G17.035', 'L01.224.050'], ['B01.050'], ['F02.463.593.071', 'G07.888.125'], ['F01.145.113'], ['G05.045', 'G16.075'], ['F01.145.209', 'L01.143'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17'], ['E05.599'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['F01.145.813'], ['F01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Alveolar macrophages fat stain in early diagnosis of fat embolism syndrome. | The aim of this study was to assess the contribution of bronchoalveolar lavage (BAL) in the diagnosis of fat embolism syndrome (FES). The presence of fat droplets in alveolar macrophages was addressed in 13 trauma patients with bone fractures and 10 non-trauma patients with acute respiratory distress syndrome (ARDS). T... | ['Adult', 'Aged', 'Biomarkers', 'Bronchoalveolar Lavage Fluid', 'Case-Control Studies', 'Embolism, Fat', 'Female', 'Fractures, Bone', 'Humans', 'Lipids', 'Macrophages, Alveolar', 'Male', 'Middle Aged', 'Prospective Studies', 'Reproducibility of Results', 'Respiratory Distress Syndrome', 'Severity of Illness Index', 'Sy... | 9,397,138 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['E05.927.100.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C14.907.355.350.454'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['A11.329.372.600', 'A11.627.482.600', 'A11.733.397.600', 'A15.382.670.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Newborn infant parasympathetic evaluation (NIPE) as a predictor of hemodynamic response in children younger than 2 years under general anesthesia: an observational pilot study. | BACKGROUND: It is still unknown whether newborn infant parasympathetic evaluation (NIPE), based on heart rate variability (HRV) as a reflection of parasympathetic nerve tone, can predict the hemodynamic response to a nociception stimulus in children less than 2 years old.METHODS: Fifty-five children undergoing elective... | ['Anesthesia, General', 'Blood Pressure', 'Female', 'Heart Rate', 'Hemodynamics', 'Humans', 'Infant', 'Male', 'Parasympathetic Fibers, Postganglionic', 'Pilot Projects', 'Predictive Value of Tests', 'Prospective Studies'] | 31,185,928 | [['E03.155.197'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A08.675.127.500.700', 'A08.675.542.100.700', 'A08.675.542.234.700', 'A08.800.050.050.050.700', 'A08.800.050.600.650', 'A08.800.80... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Low doses of gamma radiation in the management of postharvest Lasiodiplodia theobromae in mangos. | The postharvest life of mango is limited by the development of pathogens, especially fungi that cause rot, among which stands out the Lasiodiplodia theobromae. Several control methods have been employed to minimize the damages caused by this fungus, chemical control can leave residues to man and nature; physical contro... | ['Ascomycota', 'Disinfection', 'Food Handling', 'Food Microbiology', 'Gamma Rays', 'Mangifera', 'Plant Diseases'] | 26,413,068 | [['B01.300.107'], ['N06.850.780.200.450.850.375'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['B01.650.940.800.575.912.250.044.416'], ['G15.610']... | ['Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Single Restorations in the Resorbed Posterior Mandible Supported by 6-mm Implants: A 1-Year Prospective Case Series Study. | PURPOSE: The aim of this prospective case series study was to assess the clinical performance of single restorations in the posterior mandible supported by 6-mm implants.MATERIALS AND METHODS: Twenty-one consecutive patients with one or more missing premolars or molars in the posterior mandible and with an estimated bo... | ['Adult', 'Aged', 'Dental Implantation, Endosseous', 'Dental Implants, Single-Tooth', 'Dental Prosthesis, Implant-Supported', 'Dental Restoration, Permanent', 'Female', 'Humans', 'Male', 'Mandible', 'Middle Aged', 'Prospective Studies'] | 25,195,816 | [['M01.060.116'], ['M01.060.116.100'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['E06.780.346.593.185', 'E07.695.185.185'], ['E06.780.346.706', 'E07.695.190.185'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Distinct breakfast patterns on satiety perception in individuals with weight excess. | OBJECTIVES: Western dietary pattern predisposes to weight gain, insulin resistance and cardiometabolic diseases. Promoting satiety via modifications in diet composition could be useful to fight weight gain. Mediterranean diet which is recognized to be cardioprotective contains high fiber and unsaturated fat contents. W... | ['Adult', 'Aged', 'Analysis of Variance', 'Anthropometry', 'Blood Glucose', 'Blood Pressure', 'Brazil', 'Breakfast', 'Cholesterol', 'Cross-Over Studies', 'Diet, Mediterranean', 'Diet, Western', 'Energy Intake', 'Female', 'Humans', 'Insulin', 'Insulin Resistance', 'Male', 'Middle Aged', 'Overweight', 'Reference Values',... | 26,910,624 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['Z01.107.757.176'], ['G07.203.300.590.120', 'J02.500.590.120'], ['D04.210.500.247.222... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens. | An in vivo mutation assay has been developed based on flow cytometric enumeration of glycosylphosphatidylinositol (GPI) anchor-deficient rat erythrocytes. With this method, blood is incubated with anti-CD59-PE and SYTO 13 dye, and flow cytometry is used to score the frequency of CD59-negative erythrocytes. The experime... | ['4-Nitroquinoline-1-oxide', '9,10-Dimethyl-1,2-benzanthracene', 'Animals', 'Benzo(a)pyrene', 'Erythrocytes', 'Ethylnitrosourea', 'Membrane Proteins', 'Methylnitrosourea', 'Mutagenicity Tests', 'Mutagens', 'Mutation', 'Rats', 'Rats, Sprague-Dawley', 'Rats, Wistar'] | 19,965,957 | [['D02.640.820.600', 'D03.633.100.810.470.450', 'D03.661.243.500'], ['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['B01.050'], ['D02.455.426.559.847.799.306.300', 'D04.615.799.306.300'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D02.065.950.594.310', 'D02.654.692.300'], ['D12.776.543'], ['D02.065.950.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The feasibility of putrescible components of municipal solid waste for biomethane production at Hyderabad, Pakistan. | This study analyzes the feasibility of putrescible components of municipal solid waste (PCMSW) such as food waste (FW) and yard waste (YW) for methane production in Pakistan. The batch experiments have been conducted at two different inoculums to substrate ratios (ISRs) by using various inoculums under mesophilic condi... | ['Anaerobiosis', 'Bioreactors', 'Methane', 'Pakistan', 'Solid Waste'] | 29,313,447 | [['G02.111.062', 'G03.078'], ['E07.115', 'J01.897.120.115'], ['D02.455.326.146.571'], ['Z01.252.245.723'], ['D20.944.730', 'N06.850.460.710.730']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Characterization of antisera against bovine prolactin for in vivo studies on prolactin function in the rat. | The IgG fraction of rabbit antisera to bovine prolactin (PRL), intended for in vivo studies on the role of PRL in the rat, was prepared and characterized in vitro and in vivo. The antibodies showed a strong reaction with bovine PRL in double diffusion, immunoelectrophoresis, radioimmunoassay and passive haemagglutinati... | ['Animals', 'Antibodies', 'Cattle', 'Cross Reactions', 'Female', 'Fluorescent Antibody Technique', 'Immune Sera', 'Immunoglobulin G', 'Lactation', 'Pituitary Gland', 'Pregnancy', 'Prolactin', 'Rats'] | 7,002,391 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['B01.050.150.900.649.313.500.380.271'], ['G12.122.281'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A12.207.152.846.500', 'D12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maxillary sinus mucopyoceles. | Mucopyoceles of the maxillary sinus are seen rarely, and their origin has been the subject of much controversy. Three cases are reported herein, accompanied by a review of the literature, to clarify some aspects of their cause, diagnosis and treatment. It has been concluded that the most common cause of mucopyoceles is... | ['Adult', 'Aged', 'Humans', 'Male', 'Maxillary Sinus', 'Mucocele', 'Prognosis', 'Radiography'] | 6,704,033 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.531.621.578'], ['C04.182.511'], ['E01.789'], ['E01.370.350.700']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Hodgkin's disease with epithelioid granulomatous reaction]. | Hodgkin's disease with a conspicuous presence of epithelioid-histiocytic elements was described as a particular subvariant of mixed type Hodgkin's disease. The authors presented four new cases. An additional increase of Langerhan's and interdigitating cells was observed in two cases, sarcoidosis-like granulomas with ep... | ['Adult', 'Aged', 'Epithelioid Cells', 'Female', 'Histiocytes', 'Hodgkin Disease', 'Humans', 'Lymph Nodes', 'Male', 'Middle Aged'] | 9,750,420 | [['M01.060.116'], ['M01.060.116.100'], ['A11.329.372.300', 'A11.627.482.300', 'A11.733.397.300', 'A15.382.670.522.300', 'A15.382.680.397.300'], ['A11.329.372.385', 'A11.627.482.385', 'A11.733.397.385', 'A15.382.670.522.385', 'A15.382.680.397.385'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B0... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structure of the mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis sp. kyushuensis and implications for membrane pore formation. | The delta-endotoxin CytB, found in parasporal inclusions of Bacillus thuringiensis subspecies kyushuensis, is a membrane pore-forming protein which is lethal to the larvae of Dipteran insects and broadly cytolytic in vitro. The crystal structure of CytB in the protoxin form has been determined by isomorphous replacemen... | ['Amino Acid Sequence', 'Bacillus thuringiensis', 'Bacillus thuringiensis Toxins', 'Bacterial Proteins', 'Bacterial Toxins', 'Crystallization', 'Endotoxins', 'Hemolysin Proteins', 'Models, Molecular', 'Molecular Sequence Data', 'Mutation', 'Porins', 'Protein Conformation'] | 8,632,451 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['D23.946.123.090'], ['D12.776.097'], ['D23.946.123'], ['E05.196.300', 'G02.171'], ['D23.946.123.329'], ['D12.776.543.695.444'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A non-canonical site reveals the cooperative mechanisms of microRNA-mediated silencing. | Although strong evidence supports the importance of their cooperative interactions, microRNA (miRNA)-binding sites are still largely investigated as functionally independent regulatory units. Here, a survey of alternative 3´UTR isoforms implicates a non-canonical seedless site in cooperative miRNA-mediated silencing. W... | ["3' Untranslated Regions", 'Alternative Splicing', 'Animals', 'Argonaute Proteins', 'Base Sequence', 'Binding Sites', 'Caenorhabditis elegans', 'Embryo, Nonmammalian', 'Gene Silencing', 'MicroRNAs', 'Models, Molecular', 'Nucleic Acid Conformation', 'RNA-Induced Silencing Complex', 'Transcription Factors'] | 28,482,037 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['D08.811.277.352.355.350.810.500', 'D08.811.277.352.700.350.810.500', 'D12.776.157.725.500.906.500', 'D12.776.664.96... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Antibodies to CBir1 are associated with glycogen storage disease type Ib. | OBJECTIVES: : Glycogen storage disease (GSD) type Ib is a congenital disorder of glycogen metabolism that is associated with neutropenia, neutrophil and monocyte dysfunction, and an inflammatory bowel disease (IBD) that mimics a Crohn disease phenotype. The enteric microflora is implicated in the pathogenesis of IBD; h... | ['Adolescent', 'Adult', 'Antibodies', 'Bacterial Proteins', 'Child', 'Child, Preschool', 'Enterocolitis', 'Female', 'Flagellin', 'Glycogen Storage Disease Type I', 'Humans', 'Incidence', 'Infant', 'Inflammatory Bowel Diseases', 'Intestines', 'Male', 'Retrospective Studies', 'Young Adult'] | 20,410,847 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.097'], ['M01.060.406'], ['M01.060.406.448'], ['C06.405.205.596', 'C06.405.469.363'], ['D12.776.097.380'], ['C16.320.565.202.449.448', 'C18.452.648.202.449.448'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Essential tremor]. | Essential tremor. Essential tremor is very common in the general population. It is a postural tremor occurring in adulthood, evolving progressively and whose severity can be very variable from one individual to another. A positive effect of alcohol is often reported. Its pathophysiology remains poorly understood but ca... | ['Essential Tremor', 'Humans', 'Propranolol', 'Radiosurgery', 'Thalamus', 'Treatment Outcome', 'Ultrasonography'] | 30,869,259 | [['C10.228.662.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.100.624.698.711', 'D02.033.755.624.698.711', 'D02.092.063.624.698.711', 'D02.455.426.559.847.638.945', 'D04.615.638.945'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['A08.186.211.200.317.826'], ['E01.789.800', 'N04.761.559.590.800... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Biochemical and biological evaluation of novel potent coumarin inhibitor of 17â-HSD type 1. | Human 17â-hydroxysteroid dehydrogenase (17â-HSD) type 1 is an enzyme that acts at the pre-receptor level. It catalyzes the NADPH-dependent reduction of the weak estrogen estrone into the most potent estrogen 17â-estradiol, which exerts proliferative effects via estrogen receptors. Overexpression of 17â-HSD type 1 in es... | ['17-Hydroxysteroid Dehydrogenases', 'Cell Line, Tumor', 'Cell Proliferation', 'Coumarins', 'Drug Evaluation, Preclinical', 'Enzyme Inhibitors', 'Escherichia coli', 'Estrogens', 'Humans', 'Solubility'] | 21,232,530 | [['D08.811.682.047.436.375'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['E05.290.750', 'E05.337.550'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.31... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nocardia nova aortitis after coronary artery bypass surgery. | Cardiac nocardiosis is a rare disease that is nearly always associated with cardiac operation. We report the case of a patient with a 10-month history of intermittent fevers after coronary artery bypass operation who presented with progressive shortness of breath and fever. He was found to have a large aortic aneurysm ... | ['Aged', 'Aortitis', 'Coronary Artery Bypass', 'Coronary Disease', 'Diagnosis, Differential', 'Echocardiography, Transesophageal', 'Humans', 'Male', 'Nocardia', 'Nocardia Infections', 'Surgical Wound Infection'] | 17,484,997 | [['M01.060.116.100'], ['C14.907.109.320', 'C14.907.940.080'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.171'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The clinical picture of terminally ill patients with lung cancer]. | An investigation has been made with regard to the clinical picture of 87 terminally ill patients with lung cancer. It has yielded the following points. 1) Seven patients had been informed of their diagnosis. 2) Intravenous hyperalimentation was administered in 78 cases (90%), oxygen therapy in 68 cases (78%), and morph... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anxiety', 'Cause of Death', 'Combined Modality Therapy', 'Delirium', 'Depression', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Morphine', 'Oxygen Inhalation Therapy', 'Parenteral Nutrition, Total', 'Respiratory Insufficiency', 'Social Support', 'Terminal Care'] | 2,501,534 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E02.186'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['F01.145.126.350'], ['B01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Septal myomectomy and coronary artery bypass in one case of hypertrophic obstructive cardiomyopathy. | UNLABELLED: Surgery of the hypertrophic cardiomyopathy remains controversial. The safest procedure and the simples procedure is the mitral valve replacement. Septal myomectomy is difficult because of the poor surgical exposure and complications: incomplete resection, complete heart block, ventricular septal defect.CASE... | ['Cardiomyopathy, Hypertrophic', 'Coronary Artery Bypass', 'Echocardiography, Transesophageal', 'Humans', 'Male', 'Mammary Arteries', 'Middle Aged', 'Mitral Valve Insufficiency', 'Perioperative Care', 'Treatment Outcome', 'Ventricular Septum'] | 20,201,256 | [['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.891.525'], ['M01.060.116.630'], ['C14.280.484.461'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Delayed blood pressure recovery after head-up tilting during sleep in preterm infants. | Dramatic changes in cardiovascular control occur in sleep during infancy, when sleep time is at a lifetime maximum. In infants born preterm there are significant cardiovascular complications later in life, and also an increased risk for sudden infant death syndrome (SIDS), possibly a result of inadequate compensation t... | ['Blood Pressure', 'Head', 'Heart Rate', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Polysomnography', 'Posture', 'Prevalence', 'Recovery of Function', 'Sleep', 'Sudden Infant Death', 'Time Factors'] | 19,895,423 | [['E01.370.600.875.249', 'G09.330.380.076'], ['A01.456'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['E01.370.520.625'], ['G11.427.695'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cyanotic limb in a newborn: a peculiar presentation of septic hip. | A 12-day-old infant presented with marked cyanosis of the right lower limb, mimicking vascular compromise. Physical examination, plain radiography, and laboratory evidence of systemic infection suggested septic arthritis of the hip. Pyoarthrosis was verified by needle aspiration and open drainage. Streptococcus pneumon... | ['Arthritis, Infectious', 'Cyanosis', 'Female', 'Hip Joint', 'Humans', 'Infant, Newborn', 'Leg', 'Male', 'Pneumococcal Infections'] | 9,435,004 | [['C01.100', 'C05.550.114.099'], ['C23.888.248'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A01.378.610.500'], ['C01.150.252.410.890.670']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sparse non-negative generalized PCA with applications to metabolomics. | MOTIVATION: Nuclear magnetic resonance (NMR) spectroscopy has been used to study mixtures of metabolites in biological samples. This technology produces a spectrum for each sample depicting the chemical shifts at which an unknown number of latent metabolites resonate. The interpretation of this data with common multiva... | ['Algorithms', 'Magnetic Resonance Spectroscopy', 'Metabolomics', 'Principal Component Analysis'] | 21,930,672 | [['G17.035', 'L01.224.050'], ['E05.196.867.519'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['E05.318.740.562']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Association between helicobacter pylori infection and primary open angle glaucoma. | AIM: to compare the prevalence of Pylori infection in patients with primary open angle glaucoma (POAG) and control group with cataract.METHODS: This is a prospective case-control study. The participants were organized in two groups. First group (case) consisted of 35 patients with POAG and second group consisted of 35 ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Bacterial', 'Case-Control Studies', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Glaucoma, Open-Angle', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Iran', 'Male', 'Middle Aged', 'Prevalence', 'Prospective Studies'] | 25,363,173 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Whole exome sequencing (WES) approach for diagnosing primary immunodeficiencies (PIDs) in a highly consanguineous community. | Primary immunodeficiencies (PIDs) are a heterogeneous group of monogenic inborn errors of immunity. The genetic causes of these diseases can be identified using whole exome sequencing (WES). Here, DNA samples from 106 patients with a clinical suspicion of PID were subjected to WES in order to test the diagnostic yield ... | ['Adolescent', 'Adult', 'Autoimmune Diseases', 'Child', 'Child, Preschool', 'Clinical Decision-Making', 'Consanguinity', 'Disease Management', 'Female', 'Genotype', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Infant', 'Infant, Newborn', 'Inflammatory Bowel Diseases', 'Israel', 'Male', 'Mutation', 'Primary Imm... | 32,135,276 | [['M01.060.057'], ['M01.060.116'], ['C20.111'], ['M01.060.406'], ['M01.060.406.448'], ['E01.055'], ['G05.090.403.180', 'G05.180'], ['N04.590.607'], ['G05.380'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C06.405.205.731', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Reference intervals for peripheral blood lymphocyte subsets in healthy adults in Lima, Peru]. | In order to establish the reference intervals (RIs) of peripheral blood lymphocyte subsets (PBL) in healthy adults in Lima (Peru), a cross-sectional study was conducted among blood donors taken in between 2011 and 2012. Based on the criteria obtained from the guidelines of the Clinical and Laboratory Standards Institut... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Female', 'Humans', 'Lymphocyte Count', 'Lymphocyte Subsets', 'Male', 'Middle Aged', 'Peru', 'Reference Values', 'Urban Population', 'Young Adult'] | 23,949,508 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595.500', 'E01.370.225.625.107.595.500', 'E05.200.500.195.107.595.500', 'E05.200.625.107.595.500', 'E05.242.195.107.595.500', 'G04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Molecular interactions in gelatin/chitosan composite films. | Gelatin and chitosan were mixed at different mass ratios in solution forms, and the rheological properties of these film-forming solutions, upon cooling, were studied. The results indicate that the significant interactions between gelatin and chitosan promote the formation of multiple complexes, reflected by an increas... | ['Chitosan', 'Gelatin', 'Polymers', 'Rheology'] | 28,554,645 | [['D05.750.078.139.500', 'D09.698.211.500'], ['D12.776.860.476'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.830', 'H01.671.808']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Nonlinear mezlocillin kinetics due to dose-dependent metabolism. | Dose-dependent kinetics of intravenous bolus-dose mezlocillin, a newly developed ureidopenicillin, have been reported by several investigators. In eight healthy subjects we examined renal, biliary, and total clearance at different steady-state levels. After infusion of doses of 22.4 +/- 1.5, 11.4 +/- 0.7, and 5.6 +/- 0... | ['Adult', 'Bile', 'Dose-Response Relationship, Drug', 'Drug Evaluation', 'Humans', 'Infusions, Parenteral', 'Kinetics', 'Male', 'Mathematics', 'Metabolic Clearance Rate', 'Mezlocillin', 'Penicillins'] | 6,220,858 | [['M01.060.116'], ['A12.200.087'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['D02.065.589.099... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Digital Solutions for Informed Decision Making: An Academic-Community Partnership for the Development of a Prostate Cancer Decision Aid for African American Men. | African American (AA) men are significantly more likely to die of prostate cancer (PrCA) than other racial groups, and there is a critical need to identify strategies for providing information about PrCA screening and the importance of informed decision making (IDM). To assess whether a computer-based IDM intervention ... | ['African Americans', 'Community-Institutional Relations', 'Decision Making', 'Decision Support Techniques', 'Focus Groups', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Information Services', 'Male', 'Mass Screening', 'Men', 'Middle Aged', 'Prostatic Neoplasms'] | 25,563,381 | [['M01.686.508.100.100', 'M01.686.754.100'], ['N04.452.822.210'], ['F02.463.785.373'], ['E05.245', 'L01.313.500.750.190'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453'], ['E01.370.500', 'E05.318.308... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A functional interaction between the p75 neurotrophin receptor interacting factors, TRAF6 and NRIF. | Neurotrophin signaling through the p75 receptor regulates apoptosis within the nervous system both during development and in response to injury. Whereas a number of p75 interacting factors have been identified, how these upstream factors function in a coordinated manner to mediate receptor signaling is still unclear. H... | ['Animals', 'Carrier Proteins', 'Cell Line', 'DNA-Binding Proteins', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Protein Binding', 'Protein Transport', 'Proteins', 'Receptor, Nerve Growth Factor', 'Receptors, Nerve Growth Factor', 'Signal Transduction', 'TNF Receptor-Associated Factor 6'] | 14,960,584 | [['B01.050'], ['D12.776.157'], ['A11.251.210'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['G02.111.679', 'G03.808'], ['G03.143.700'], ['D12.776'], ['D12.776.543.750.750.400.550.500'], ['D12.776.543.750.750.400.550'], ['G02.111.820', 'G04.835'], ['D12.644.360.024.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Growth changes in the elastic properties of human tendon structures. | The purpose of this study was to investigate the growth changes in the elastic properties of human tendon structures. 9 younger boys (age 10.8 +/- 0.9 years, YBG), 9 elder boys (14.8 +/- 0.3 years, EBG), and 14 young adult men (24.7 +/- 1.6 years, ADG) volunteered to take part in the present study. Using a B-mode ultra... | ['Adolescent', 'Adult', 'Age Factors', 'Child', 'Elasticity', 'Humans', 'Male', 'Muscle, Skeletal', 'Tendons', 'Tensile Strength'] | 11,281,617 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567', 'A10.690.552.500'], ['A02.880'], ['G01.374.850']] | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glucose metabolism after pancreas transplantation. | After pancreas transplantation in type-I diabetics the dependency on exogenous insulin usually vanishes rapidly. In about 50% of patients fasting and postprandial blood glucose concentrations are normal but by oral glucose tolerance tests the glucose metabolism is classified as normal in a minority. Some of the reasons... | ['Diabetes Mellitus, Type 1', 'Glucose', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Pancreas Transplantation', 'Regional Blood Flow'] | 3,553,998 | [['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D09.947.875.359.448'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['E04.210.725', 'E04.936.450.650'], ['G09.330.100.780']... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The dissociation and separation of bovine adenohypophysial cells. | Bovine adenhypophysial tissue was dissociated by sequential enzymatic incubation in a continuous flow system. Dispersed cells separated into discrete fractions after centrifugation in isopycnic bovine serum albumin gradients. The dispersed and separated cells were prepared for microscopic identification and differentia... | ['Animals', 'Cattle', 'Cell Separation', 'Centrifugation, Isopycnic', 'Female', 'Follicle Stimulating Hormone', 'Luteinizing Hormone', 'Male', 'Pituitary Gland, Anterior', 'Prolactin', 'Thyrotropin'] | 95,171 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation between brachial artery flow-mediated dilation and endothelial microparticle levels for identifying endothelial dysfunction in children with Kawasaki disease. | BACKGROUND: We investigated vascular endothelial dysfunction by sonographic features of flow-mediated dilation (FMD) and circulating endothelial microparticles (EMPs) in Kawasaki disease (KD).METHODS: Twenty-eight patients with KD were prospectively grouped according to stage of disease: acute, subacute, and convalesce... | ['Biomarkers', 'Brachial Artery', 'Case-Control Studies', 'Cell-Derived Microparticles', 'Child', 'Child, Preschool', 'China', 'Echocardiography', 'Endothelium, Vascular', 'Female', 'Flow Cytometry', 'Humans', 'Infant', 'Male', 'Mucocutaneous Lymph Node Syndrome', 'Prospective Studies', 'Regional Blood Flow', 'Statisti... | 24,336,465 | [['D23.101'], ['A07.015.114.139'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.284.295.588.500'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.015.700.500', 'A10.272.491.355'], ['E01.370.2... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Dipole localization and test-retest reliability of frequency and duration mismatch negativity generator processes. | The mismatch negativity (MMN) is an event related potential component elicited by changes in duration, frequency or intensity of the stimuli during repetitive series of equal standard stimuli. In the present study we compared duration and frequency MMN using dipole source analysis concerning both the test-retest reliab... | ['Adult', 'Artifacts', 'Brain', 'Brain Mapping', 'Electroencephalography', 'Electrophysiology', 'Evoked Potentials', 'Evoked Potentials, Visual', 'Humans', 'Middle Aged', 'Reproducibility of Results', 'Visual Perception'] | 9,358,949 | [['M01.060.116'], ['E05.047'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300', 'E01.370.405.245'], ['H01.158.344.528', 'H01.158.782.236'], ['G07.265.216.500', 'G11.561.200.500'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The anemia of heart failure. | Anemia is common in congestive heart failure (CHF) and is associated with an increased mortality and morbidity. The most likely causes of anemia are chronic kidney disease (CKD) and excessive cytokine production, both of which can cause depression of erythropoietin (EPO) production and bone marrow activity. The cytokin... | ['Anemia', 'Erythropoietin', 'Heart Failure', 'Hemoglobins', 'Humans', 'Prevalence', 'Thrombocytosis'] | 19,907,148 | [['C15.378.071'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['C14.280.434'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.75... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Electropermeabilization of endocytotic vesicles in B16 F1 mouse melanoma cells. | It has been reported previously that electric pulses of sufficiently high voltage and short duration can permeabilize the membranes of various organelles inside living cells. In this article, we describe electropermeabilization of endocytotic vesicles in B16 F1 mouse melanoma cells. The cells were exposed to short, hig... | ['Animals', 'Cell Membrane', 'Cell Membrane Permeability', 'Electroporation', 'Isoquinolines', 'Melanoma, Experimental', 'Mice', 'Propidium', 'Transport Vesicles', 'Tumor Cells, Cultured'] | 20,361,267 | [['B01.050'], ['A11.284.149'], ['G03.143.335', 'G04.175'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['D03.633.100.531'], ['C04.557.465.625.650.510.525', 'C04.557.580.625.650.510.525', 'C04.557.665.510.525', 'C04.619.600', 'E05.598.500.496.937'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.633.300.633.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning of two individual cDNAS encoding 9-cis-epoxycarotenoid dioxygenase from Gentiana lutea, their tissue-specific expression and physiological effect in transgenic tobacco. | Two 9-cis-epoxycarotenoid dioxygenase (NCED) cDNAs have been cloned from a petal library of Gentiana lutea. Both cDNAs carry a putative transit sequence for chloroplast import and differ mainly in their length and the 5'-flanking regions. GlNCED1 was evolutionary closely related to Arabidopsis thaliana NCED6 whereas Gl... | ['Adaptation, Physiological', 'Dioxygenases', 'Flowers', 'Gene Expression Regulation, Plant', 'Gentiana', 'Germination', 'Oxygenases', 'Plant Proteins', 'Plants, Genetically Modified', 'Sequence Analysis, DNA', 'Tobacco', 'Transformation, Genetic', 'Water'] | 16,618,520 | [['G07.025', 'G16.012.500'], ['D08.811.682.690.416'], ['A18.024.249.500'], ['G05.308.375'], ['B01.650.940.800.575.912.250.456.750.391'], ['G07.345.625.249', 'G15.357'], ['D08.811.682.690'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['E05.393.760.700'], ['B01.650.940.800.575.912.250.908.500.900'], ['G05.728.865']... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of bone mineral density with hemoglobin and change in hemoglobin among older men and women: The Cardiovascular Health Study. | PURPOSE: Osteoblasts and their precursors support hematopoiesis in the bone marrow. We hypothesized that declines in Hgb levels are associated with bone mineral density (BMD).METHODS: The Cardiovascular Health Study is a prospective longitudinal study that enrolled 5888 community-dwelling adults aged >65 years and meas... | ['Aged', 'Bone Density', 'Cardiovascular System', 'Female', 'Hemoglobins', 'Humans', 'Leukocyte Count', 'Male'] | 30,448,304 | [['M01.060.116.100'], ['G11.427.100'], ['A07'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105.595']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Early intervention for adolescents at high risk for the development of bipolar disorder: pilot study of Interpersonal and Social Rhythm Therapy (IPSRT). | Interpersonal and Social Rhythm Therapy (IPSRT) delays bipolar disorder (BP) recurrence in adults by stabilizing daily routines and sleep/wake cycles. Because adolescence is a key developmental stage for illness onset and altered social and sleep patterns, this period may prove optimal for intervention with adolescents... | ['Adaptation, Psychological', 'Adolescent', 'Bipolar Disorder', 'Chronobiology Disorders', 'Early Medical Intervention', 'Family Conflict', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Internal-External Control', 'Interpersonal Relations', 'Life Change Events', 'Male', 'Patient Education as Topic', 'Person... | 24,377,402 | [['F01.058'], ['M01.060.057'], ['F03.084.500'], ['C10.281'], ['N02.421.726.363'], ['F01.829.263.370.054', 'F01.829.401.142'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F01.829.401'], ['F01.829.458.410'], ['I02.233.332.500', 'N02.421.726.407.680'], ['F04.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Neuronal injury in hippocampus with human immunodeficiency virus transactivating protein, Tat. | Patients with human immunodeficiency virus infection may develop a dementing illness. Using both in vitro and in vivo models, we investigated the susceptibility of the hippocampal formation to the Tat protein of human immunodeficiency virus. We also determined the pattern of hippocampal injury in patients with human im... | ['Adolescent', 'Adult', 'Animals', 'Dose-Response Relationship, Drug', 'Gene Products, tat', 'Hippocampus', 'Humans', 'In Vitro Techniques', 'Male', 'Middle Aged', 'Neurons', 'Rats'] | 12,605,891 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.260.755.199', 'D12.776.930.900.199', 'D12.776.964.900.750.750', 'D12.776.964.925.984.400'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['M01.06... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Examination of circulating stem cells from the granulocyte-monocyte line in patients with Hodgkin's disease]. | The formation of granulocyte-monocyte colonies by bone marrow cells cultured in a semiliquid environment is a widely applied technique of granulocytopoiesis examination. Applying this method the number of circulating in blood stem cells of the granulocyte-monocyte line (CFC-GM) has been assessed in 35 patients with Hod... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Female', 'Granulocytes', 'Hematopoietic Stem Cells', 'Hodgkin Disease', 'Humans', 'Leukocyte Count', 'Male', 'Mechlorethamine', 'Middle Aged', 'Monocytes', 'Prednisone', 'Procarbazine', 'Vincristine'] | 2,356,144 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Quick-and-clean article figures with FigureJ. | We created FigureJ a new ImageJ plugin dedicated to scientific article figures preparation. Building a convincing figure is a demanding task that covers different steps ranging from content acquisition to figure assembly in editing software. Notions of image processing are required when it comes to even simple tasks su... | ['Image Processing, Computer-Assisted', 'Publishing', 'Software'] | 23,906,423 | [['L01.224.308'], ['L01.737'], ['L01.224.900']] | ['Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Simian varicella virus infects ganglia before rash in experimentally infected monkeys. | Monkeys experimentally infected with simian varicella virus (SVV) develop rash 10-14 days later. However, the route and the time of ganglionic infection are unknown. Using PCR, we analyzed DNA extracted from tissues of 13 monkeys 5 to 60 days after either intratracheal or intravenous inoculation with SVV. SVV DNA was d... | ['Animals', 'Chlorocebus aethiops', 'DNA, Viral', 'Exanthema', 'Ganglia', 'Herpesviridae Infections', 'Polymerase Chain Reaction', 'Varicellovirus'] | 11,145,914 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D13.444.308.568'], ['C17.800.257'], ['A08.340'], ['C01.925.256.466'], ['E05.393.620.500'], ['B04.280.382.100.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of a nurse-coordinated prevention programme on cardiovascular risk after an acute coronary syndrome: main results of the RESPONSE randomised trial. | OBJECTIVE: To quantify the impact of a practical, hospital-based nurse-coordinated prevention programme on cardiovascular risk, integrated into the routine clinical care of patients discharged after an acute coronary syndrome, as compared with usual care only.DESIGN: RESPONSE (Randomised Evaluation of Secondary Prevent... | ['Acute Coronary Syndrome', 'Aged', 'Ambulatory Care', 'Chi-Square Distribution', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Medication Adherence', 'Middle Aged', 'Netherlands', 'Patient Education as Topic', 'Risk Assessment', 'Risk Factors', 'Risk Reduction Behavior', 'Secondary Prevention',... | 23,813,851 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.600.500', 'F01.14... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A homoallelic FECH mutation in a patient with both erythropoietic protoporphyria and palmar keratoderma. | BACKGROUND: Erythropoietic protoporphyria (EPP) is a hereditary disorder caused by the deficiency of ferrochelatase (FECH) in the haem biosynthetic pathway. In the majority of families, EPP is transmitted as a pseudodominant trait. Autosomal recessive form of EPP is found in only about 3% of the families.OBJECTIVES: In... | ['Child', 'Family Health', 'Ferrochelatase', 'Genes, Recessive', 'Haplotypes', 'Homozygote', 'Humans', 'Keratoderma, Palmoplantar', 'Male', 'Models, Genetic', 'Mutation, Missense', 'Protoporphyria, Erythropoietic'] | 20,337,824 | [['M01.060.406'], ['N01.400.300'], ['D08.811.520.500', 'D12.776.157.427.374.375.957', 'D12.776.556.579.374.375.617', 'D12.776.575.562'], ['G05.360.340.024.340.415', 'G05.420.325'], ['G05.380.360'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.850.475', 'C17.800.428.435', 'C17.800.827.475'... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Treatment of fractures of long bones associated with extensive skin avulsion]. | The work analyses the experience in the treatment of 46 patients with fractures of long tubular bones and extensive wounds with avulsion of the skin at the department of emergency traumatology from 1983 to 1988. The method of choice in the treatment of fractures of the long tubular bones in this category of patients is... | ['Adolescent', 'Adult', 'Amputation, Traumatic', 'Arm Injuries', 'Body Surface Area', 'Child', 'Dermatologic Surgical Procedures', 'External Fixators', 'Female', 'Fracture Fixation, Internal', 'Fractures, Bone', 'Humans', 'Leg Injuries', 'Male', 'Middle Aged', 'Multiple Trauma', 'Replantation', 'Skin', 'Skin Transplant... | 1,469,873 | [['M01.060.057'], ['M01.060.116'], ['C26.062'], ['C26.088'], ['E01.370.600.115.100.231', 'E05.041.124.231', 'G07.100.100.231'], ['M01.060.406'], ['E04.680.275'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['E04.555.300.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['M01.060.116.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mammareconstruction with skin-expander and silicone prostheses: 15 years' experience. | We report on 170 breasts that were reconstructed with Skin-Expander and silicone implants over a period of 15 years [1,2]. Reconstruction occurred primarily in only about one-third of the cases, since the information provided by the first doctor in charge regarding the possibilities of breast reconstruction was rather ... | ['Adult', 'Breast Implants', 'Breast Neoplasms', 'Female', 'Humans', 'Mammaplasty', 'Mastectomy', 'Middle Aged', 'Tissue Expansion', 'Tissue Expansion Devices'] | 12,140,703 | [['M01.060.116'], ['E07.695.140'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['E04.466'], ['M01.060.116.630'], ['E04.680.800'], ['E07.695.800', 'E07.858.886']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mechanical unfolding of segment-swapped protein G dimer: results from replica exchange molecular dynamics simulations. | The protein G dimer (pdb code 1Q10) is a mutated dimeric form of the immunoglobulin-binding domain B1 of streptococcal protein G, in which the two monomeric units have swapped elements of their secondary structure. We have used replica exchange molecular dynamics simulations to study how this dimer responds to a mechan... | ['Bacterial Proteins', 'Computer Simulation', 'Dimerization', 'Immunoglobulins', 'Models, Chemical', 'Protein Conformation', 'Protein Folding', 'Protein Structure, Secondary', 'Protein Subunits'] | 16,854,158 | [['D12.776.097'], ['L01.224.160'], ['G02.206', 'G03.230'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['E05.599.495'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.600'], ['D12.776.813']] | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Plasma levels of angiostatin and endostatin remain unchanged for the first 3 weeks after colorectal cancer surgery. | INTRODUCTION: Angiostatin and endostatin are endogenous inhibitors of angiogenesis with anticancer effects. After minimally invasive colorectal resection (MICR), blood levels of the proangiogenic factors vascular endothelial growth factor (VEGF) and angiopoetin 2 (Ang-2) are elevated for 2-4 weeks. Also, postoperative ... | ['Adenocarcinoma', 'Aged', 'Aged, 80 and over', 'Angiopoietin-2', 'Angiostatins', 'Colectomy', 'Colorectal Neoplasms', 'Endostatins', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Postoperative Period', 'Vascular Endothelial Growth Factor A'] | 21,181,203 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.644.276.100.100.200', 'D12.776.467.100.100.200', 'D23.529.100.100.200'], ['D08.622.610.500', 'D12.644.276.100.450.500', 'D12.776.124.790.223.580.500', 'D12.776.377.715.182.580.500', 'D12.776.467.100.450.500', 'D12.776.811.243.610.500', 'D23.5... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of psychological functioning in women at different stages of in vitro fertilization treatment using the mean affect adjective check list. | PURPOSE: The objectives were to identify the stage/s of IVF treatment where a woman is most vulnerable to psychological stress, and to assess the Mean Affect Adjective Check List (MAACL) as a measure of psychological functioning during IVF treatment, which has hitherto not been reported.METHODS: Thirty-seven women unde... | ['Age Factors', 'Anxiety', 'Depression', 'Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Hostility', 'Humans', 'Infertility, Female', 'Psychometrics', 'Statistics, Nonparametric', 'Stress, Psychological', 'Surveys and Questionnaires'] | 11,209,535 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.470.132'], ['F01.145.126.350'], ['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['F01.470.596'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['F04.711.780'], ['E05.318.740.995', 'N05.715.360.750.760', 'N06.850.5... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Surface tension and intrinsic amyloid fluorescence of serum and cerebrospinal fluid samples in Alzheimer?s disease. | AIM: Surface tension of biological fluids can be influenced by changes in oligomerization or aggregation of surfactant peptides or proteins. Amphiphilic peptides of amyloid-â or other amyloidogenic peptides/proteins display properties of surfactants, oligomerization and aggregation increase also their fluorescence inte... | ['Adult', 'Aged', 'Alzheimer Disease', 'Amyloid', 'Biomarkers', 'Case-Control Studies', 'Female', 'Fluorescence', 'Follow-Up Studies', 'Humans', 'Male', 'Prognosis', 'Surface Tension'] | 30,888,831 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D05.500.049', 'D12.776.049'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E05.318.372.500.750.249', 'N05.715.3... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rabies virus in insectivorous bats: implications of the diversity of the nucleoprotein and glycoprotein genes for molecular epidemiology. | Insectivorous bats are the main reservoirs of rabies virus (RABV) in various regions of the world. The aims of this study were to (a) establish genealogies for RABV strains from different species of Brazilian insectivorous bats based on the nucleoprotein (N) and glycoprotein (G) genes, (b) investigate specific RABV lin... | ['Animals', 'Antigens, Viral', 'Brazil', 'Chiroptera', 'Genetic Variation', 'Glycoproteins', 'Mice', 'Molecular Epidemiology', 'Nucleocapsid Proteins', 'Polymerase Chain Reaction', 'Rabies', 'Rabies virus', 'Sequence Analysis, DNA', 'Species Specificity', 'Viral Envelope Proteins'] | 20,609,456 | [['B01.050'], ['D23.050.327'], ['Z01.107.757.176'], ['B01.050.150.900.649.313.937'], ['G05.365'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.318.416', 'E05.393.522', 'H01.158.201.636.475.500', 'H01.158.273.343.595.475.500', 'H01.181.122.650.475.550', 'H02.403.720.500.300', 'N06.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Origin, structure, and role of background EEG activity. Part 1. Analytic amplitude. | OBJECTIVE: To explain the neural mechanisms of spontaneous EEG by measuring the spatiotemporal patterns of synchrony among beta-gamma oscillations during perception.METHODS: EEGs were measured from 8 x 8 (5.6 x 5.6 mm2) arrays fixed on the surfaces of primary sensory areas in rabbits that were trained to discriminate v... | ['Acoustic Stimulation', 'Algorithms', 'Animals', 'Conditioning, Psychological', 'Discrimination, Psychological', 'Electroencephalography', 'Entropy', 'Models, Neurological', 'Neocortex', 'Photic Stimulation', 'Rabbits', 'Touch'] | 15,294,210 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['G17.035', 'L01.224.050'], ['B01.050'], ['F02.463.425.179'], ['F02.463.593.257'], ['E01.370.376.300', 'E01.370.405.245'], ['G01.906.345'], ['E05.599.395.642'], ['A08.186.211.200.885.287.500.420'], ['E05.723.729'], ['B01.050.150.900.649.313.968.700'], ['F02.830.816.850', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53. | We recently reported that cytosine arabinoside (AraC)-induced apoptosis of cerebellar neurons involves the overexpression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). The present study was undertaken to investigate whether p53 and/or Bax overexpression participates in the AraC-induced apoptosis of cerebellar gr... | ['Animals', 'Apoptosis', 'Cerebellum', 'Cytarabine', 'Gene Expression Regulation', 'Gene Expression Regulation, Enzymologic', 'Genes, p53', 'Glyceraldehyde-3-Phosphate Dehydrogenases', 'Mice', 'Mice, Knockout', 'Neurons', 'Oligodeoxyribonucleotides, Antisense', 'PC12 Cells', 'Proto-Oncogene Proteins', 'Proto-Oncogene P... | 10,531,467 | [['B01.050'], ['G04.146.954.035'], ['A08.186.211.132.810.428.200'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['G05.308'], ['G05.308.320'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['D08.811.682.657.163.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Lipopolysaccharide, TNFá, IL-6, dexamethasone, and insulin increase the expression of GPR54 in the MCF7 breasr cancer cell line]. | OBJECTIVE: To investigate the effects of different concentrations of lipopolysaccharide (LPS), tumor necrosis factor á (TNFá), interleukin-6 (IL-6), dexamethasone (Dex), and insulin on the mRNA and protein expressions of GPR54 in the MCF7 cell line in vitro.METHODS: MCF7 breasr cancer cells were cultured and treated wi... | ['Blotting, Western', 'Dexamethasone', 'Glucocorticoids', 'Gonads', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Interleukin-6', 'Lipopolysaccharides', 'MCF-7 Cells', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Receptors, G-Protein-Coupled', 'Receptors, Kisspeptin-1', 'Time Factors', 'Tumor Necrosis Facto... | 26,333,218 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['A05.360.576', 'A06.300.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.69... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urinary nerve growth factor levels could be a biomarker for overactive bladder symptom: a meta-analysis. | To examine whether urinary tract nerve growth factor (uNGF) could be a biomarker for overactive bladder (OAB) symptom, we conducted a comprehensive meta-analysis of 8 case-control studies. In all the studies considered, patients with OAB symptom had a higher uNGF level compared to healthy people. In addition, patients ... | ['Biomarkers', 'Case-Control Studies', 'Humans', 'Nerve Growth Factor', 'Urinary Bladder, Overactive'] | 24,782,215 | [['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.860.437', 'D12.776.467.860.437', 'D12.776.631.600.437', 'D23.529.850.437'], ['C12.777.829.866', 'C13.351.968.829.813', 'C23.888.942.343.780']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Locus coeruleus lesions potentiate neurotoxic effects of MPTP in dopaminergic neurons of the substantia nigra. | The observation that Parkinson's disease (PD) is associated with locus coeruleus (LC) noradrenergic neuronal degeneration suggests that the LC noradrenergic system may be involved in the pathogenesis and natural progression of the destruction of the substantia nigra (SN) dopaminergic neurons in Parkinson's disease. The... | ['Animals', 'Base Sequence', 'Dopamine', 'Immunohistochemistry', 'In Situ Hybridization', 'Locus Coeruleus', 'MPTP Poisoning', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Norepinephrine', 'Oxidopamine', 'RNA, Messenger', 'Substantia Nigra', 'Tyrosine 3-Monooxygenase'] | 7,704,612 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Induction of N-methyl-D-asparate receptor mediated c-fos protein in the rat brain by incomplete ischaemia. | The expression of c-fos protein was examined by means of immunocytochemistry in the rat brain following incomplete ischaemia, to elucidate the molecular mechanisms of post-ischaemic neuronal death and of the modulated neurotransmission of surviving neurons. Incomplete ischaemia was produced by permanent unilateral or b... | ['Animals', 'Brain', 'Carotid Artery, Common', 'Dizocilpine Maleate', 'Ischemic Attack, Transient', 'Ligation', 'Male', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Receptors, N-Methyl-D-Aspartate'] | 7,829,168 | [['B01.050'], ['A08.186.211'], ['A07.015.114.186.200'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['E04.426'], ['D12.776.260.108.765', 'D12.776.624.664.700.179', 'D12.776.660.760', 'D12.776.930.127.765'], ['B01.050.150.900.649.313.992.635.505.700'], ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunophenotypic and genotypic characterization of B-cell chronic lymphocytic leukemia patients from northern Italy. | BACKGROUND AND METHODS: Immunoglobulin (Ig) gene expression and rearrangements provide information about cell lineage, clonality and differentiation of neoplastic lymphoid cells. We performed flow cytometry and Southern blot analysis in 25 patients with chronic lymphocytic leukemia (CLL) from the Po River delta region ... | ['Clone Cells', 'DNA, Neoplasm', 'Female', 'Gene Expression Regulation, Neoplastic', 'Gene Rearrangement, B-Lymphocyte', 'Genes, Immunoglobulin', 'Genotype', 'Humans', 'Immunoglobulin kappa-Chains', 'Immunoglobulin lambda-Chains', 'Immunophenotyping', 'Italy', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Male', 'Neoplasm... | 8,491,418 | [['A11.251.353'], ['D13.444.308.425'], ['G05.308.370'], ['G05.344.401', 'G12.500.274'], ['G05.360.340.024.340.335', 'G12.500.299'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.705.750.530', 'D12.776.124.790.651.705.750.530', 'D12.776.377.715.548.705.750.530'], ['D12.776.124.486.4... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[Maternity, sterility and reproduction technology]. | The idea of maternity--and paternity as well--reaches far beyond the field of biological reproduction inasmuch as it implies a subject's desire, besides being regulated by the symbolic order: Language, myths, patterns and values of a given culture. From this point of view, infertility cannot be considered as a mere som... | ['Adult', 'Female', 'Fertilization in Vitro', 'Humans', 'Infertility, Female', 'Infertility, Male', 'Insemination, Artificial', 'Male', 'Maternal Behavior', 'Ovulation Induction', 'Paternal Behavior', 'Pregnancy', 'Reproductive Techniques'] | 7,992,630 | [['M01.060.116'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['C12.294.365.700'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['F01.829.263.370.215'], ['E02.875.800.984', 'E05.820.800.984'], ['F01.829.263.370.330'], ['G08.686.784.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Therapeutic activity of Physioquens in the treatment of certain gynecological conditions (author's transl)]. | The new hormonal preparation Physioquens was administered during the study to 181 women during 1.634 cycles and has proved to be very effective in the treatment of various gynaecological disturbances. A definitive reduction has been observed in premenstrual and pre and postmenopausal complaints, dysmenorrhoea, amenorr... | ['Drug Evaluation', 'Ethinyl Estradiol', 'Female', 'Humans', 'Lynestrenol', 'Menopause', 'Menstruation Disturbances', 'Pregnancy'] | 1,213,240 | [['E05.290.625', 'E05.337.425'], ['D04.210.500.668.651.568.291', 'D06.472.334.851.437.968.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.668.651.693.494'], ['G08.686.157.500', 'G08.686.841.249.500'], ['C23.550.568'], ['G08.686.784.769']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Asymmetric effects of cooler and warmer winters on beech phenology last beyond spring. | In temperate trees, the timings of plant growth onset and cessation affect biogeochemical cycles, water, and energy balance. Currently, phenological studies largely focus on specific phenophases and on their responses to warming. How differently spring phenology responds to the warming and cooling, and affects the subs... | ['Climate', 'Climate Change', 'Cold Temperature', 'Fagus', 'Hot Temperature', 'Plant Development', 'Seasons', 'Trees'] | 28,464,396 | [['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.175.374'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['B01.650.940.800.575.912.250.859.750.300.249'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Working conditions and health in Central America: a survey of 12,024 workers in six countries. | OBJECTIVE: To describe the survey methodology and initial general findings of the first Central American Survey of Working Conditions and Health.METHODS: A representative sample of 12,024 workers was interviewed at home in Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama. Questionnaire items addressed... | ['Accidents, Occupational', 'Adult', 'Central America', 'Contracts', 'Cumulative Trauma Disorders', 'Data Collection', 'Developing Countries', 'Employment', 'Female', 'Hazardous Substances', 'Health', 'Hot Temperature', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Occupational Exposure', 'Social Security', ... | 24,652,231 | [['N06.850.135.240'], ['M01.060.116'], ['Z01.107.169'], ['I01.880.604.583.090', 'N03.706.535.241'], ['C26.844.150'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['I01.615.500.300'], ['N01.824.245'], ['D27.888.426'], ['N01.400'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.7... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Preliminary studies on DNA retardation by MutS applied to the detection of point mutations in clinical samples. | MutS ability to bind DNA mismatches was applied to the detection of point mutations in PCR products. MutS recognized mismatches from single up to five nucleotides and retarded the electrophoretic migration of mismatched DNA. The electrophoretic detection of insertions/deletions above three nucleotides is also possible ... | ['Cell Cycle Proteins', 'DNA', 'DNA-Binding Proteins', 'Genes, BRCA1', 'Multiple Endocrine Neoplasia Type 2b', 'MutS Homolog 2 Protein', 'Nuclear Proteins', 'Oncogene Proteins', 'Point Mutation', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-ret', 'Receptor Protein-Tyrosine Kinases'] | 15,680,407 | [['D12.776.167'], ['D13.444.308'], ['D12.776.260'], ['G05.360.340.024.340.375.249.100', 'G05.360.340.024.340.415.400.100'], ['C04.588.322.400.510', 'C04.651.600.510', 'C04.700.630.510', 'C16.320.700.630.510', 'C19.344.400.510'], ['D08.811.074.844.750', 'D08.811.277.040.025.292.750', 'D12.776.260.556.750', 'D12.776.624.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of a novel collagen type ?-binding protein from Streptococcus suis serotype 2. | Streptococcus suis, a major pathogen of pigs, is an emerging zoonotic agent that causes meningitis and septic shock. cbp40 is a putative virulent gene that has been identified using suppression subtractive hybridization performed on the virulent S. suis serotype 2 strain HA9801 and the avirulent S. suis serotype 2 stra... | ['Animals', 'Bacterial Adhesion', 'Bacterial Proteins', 'Biofilms', 'Cloning, Molecular', 'Epithelial Cells', 'Gene Expression Regulation, Bacterial', 'Hep G2 Cells', 'Humans', 'Streptococcal Infections', 'Streptococcus suis', 'Swine', 'Zebrafish'] | 23,465,548 | [['B01.050'], ['G06.099.050'], ['D12.776.097'], ['A20.593', 'G06.120'], ['E05.393.220'], ['A11.436'], ['G05.308.300'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.890'], ['B03.353.750.737.872.750', 'B03.510.400.800.872.750', 'B03.510.550.737.872.750'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors. | IFN regulatory factors (IRFs) constitute a family of transcription factors that are involved in IFN signaling and the development and differentiation of the immune system. Targeted gene disruption studies in mice assigned their primary role to the immune system. Two lymphoid-specific IRF members, IFN consensus sequence... | ['3T3 Cells', 'Amino Acid Motifs', 'Amino Acid Sequence', 'Animals', 'Consensus Sequence', 'DNA', 'DNA-Binding Proteins', 'Interferon Regulatory Factor-2', 'Interferon Regulatory Factors', 'Interferons', 'Mice', 'Molecular Sequence Data', 'Protein Structure, Tertiary', 'Proto-Oncogene Proteins', 'Repressor Proteins', '... | 10,586,038 | [['A11.251.210.100', 'A11.329.228.100'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.580.175'], ['D13.444.308'], ['D12.776.260'], ['D12.644.360.024.302.249', 'D12.776.157.057.050.249', 'D12.776.260.504.249', 'D12.776.476.024.385.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Association between adiposity and inflammatory markers in maternal and fetal blood in a group of Mexican pregnant women. | In the present pilot study, we evaluated the effect of maternal adiposity on the plasma concentration of adipocytokines in pregnant women and their newborns. Twenty patients with term gestations without labour were initially selected by pregestational BMI and then classified into two study groups (n 10 each), according... | ['Adipokines', 'Adiponectin', 'Adiposity', 'Adult', 'Biomarkers', 'Birth Weight', 'Cytokines', 'Female', 'Fetal Blood', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Inflammation', 'Leptin', 'Male', 'Maternal Age', 'Mexico', 'Pilot Projects', 'Pregnancy', 'Young Adult'] | 20,650,016 | [['D06.472.699.042', 'D12.644.276.024', 'D12.644.548.011', 'D12.776.467.024', 'D23.529.024'], ['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.116']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Baroreceptor reflexes in human hypertension. | We studied the control of arterial pressure by the carotid sinus baroreceptors in 35 hypertensive humans, using a variable pressure neck chamber to alter carotid sinus transmural pressure in a graded fashion. The results were compared with those obtained from 11 normotensives. As in normotensives, reduction in carotid ... | ['Adult', 'Aged', 'Blood Pressure', 'Carotid Arteries', 'Female', 'Heart Rate', 'Hemodynamics', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Nitroglycerin', 'Phenylephrine', 'Pressoreceptors', 'Reflex'] | 97,032 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.114.186'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['D02.640.636'], ['D02.033.100.291.617', 'D02.092.063.291.617'], ['A... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of a multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits. | We previously developed a method of partitioning genetic variance of a quantitative trait to loci in specific chromosomal regions. In this paper, we compare this method--multipoint IBD (identical by descent) method (MIM)--with parametric multipoint linkage analysis (MLINK). A simulation study was performed comparing th... | ['Chromosome Mapping', 'Computer Simulation', 'Confounding Factors, Epidemiologic', 'Gene Frequency', 'Genes, Dominant', 'Genetic Linkage', 'Genetic Markers', 'Genetic Variation', 'Humans', 'Likelihood Functions', 'Lod Score', 'Models, Genetic', 'Parents'] | 1,539,596 | [['E05.393.183'], ['L01.224.160'], ['N05.715.350.240', 'N06.850.490.718'], ['G05.330'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.75... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Quantitative NMRI and NMRS identify augmented disease progression after loss of ambulation in forearms of boys with Duchenne muscular dystrophy. | Quantitative NMRI and (31)P NMRS indices are reported in the forearms of 24 patients with Duchenne muscular dystrophy (DMD) (6-18 years, 14 non-ambulant) amenable to exon 53 skipping therapy and in 12 age-matched male controls (CONT). Examinations carried out at 3 T comprised multi-slice 17-echo measurements of muscle ... | ['Adenosine Triphosphate', 'Adolescent', 'Child', 'Disease Progression', 'Forearm', 'Humans', 'Magnetic Resonance Imaging', 'Magnetic Resonance Spectroscopy', 'Male', 'Muscular Dystrophy, Duchenne'] | 26,215,733 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['M01.060.057'], ['M01.060.406'], ['C23.550.291.656'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E05.196.867.519'], ['C05.651.534.500.300', 'C10.668.491.175.500.300', 'C16.320.322.562',... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Correction of intermetatarsal angle in hallux valgus using small suture button device. | BACKGROUND: Hallux valgus is a common foot ailment causing pain and disability, and correction of the intermetatarsal angle (IMA) deformity is often accomplished using a first metatarsal distal or proximal osteotomy. These osteotomies can be technically challenging and may lead to complications such as loss of fixation... | ['Adult', 'Female', 'Foot Joints', 'Hallux Valgus', 'Humans', 'Male', 'Middle Aged', 'Orthopedic Fixation Devices', 'Radiography', 'Retrospective Studies', 'Toe Joint', 'Treatment Outcome', 'Wound Healing'] | 23,559,614 | [['M01.060.116'], ['A02.835.583.378'], ['C05.330.610'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.858.442.660', 'E07.858.690.725'], ['E01.370.350.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mobile marine predators: an understudied source of nutrients to coral reefs in an unfished atoll. | Animal movements can facilitate important ecological processes, and wide-ranging marine predators, such as sharks, potentially contribute significantly towards nutrient transfer between habitats. We applied network theory to 4 years of acoustic telemetry data for grey reef sharks (Carcharhinus amblyrhynchos) at Palmyra... | ['Acoustics', 'Animal Migration', 'Animals', 'Coral Reefs', 'Ecosystem', 'Female', 'Male', 'Nitrogen Cycle', 'Nutrients', 'Population Density', 'Predatory Behavior', 'Seawater', 'Sex Factors', 'Sharks', 'Telemetry', 'Time Factors'] | 29,563,260 | [['H01.671.031'], ['F01.145.113.069.500'], ['B01.050'], ['G16.500.275.157.130', 'N06.230.124.130'], ['G16.500.275.157', 'N06.230.124'], ['G02.111.587', 'G02.607.560', 'G16.500.768'], ['G07.203.300.681', 'J02.500.681'], ['N01.224.600', 'N06.850.505.400.600'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['G16.500.275... | ['Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Changes in choroidal thickness in relation to the severity of retinopathy and macular edema in type 2 diabetic patients. | PURPOSE: To assess changes in choroidal thickness in type 2 diabetic patients with diabetic retinopathy (DR) and diabetic macular edema (DME) using enhanced-depth imaging spectral domain optical coherence tomography (EDI-OCT).METHODS: Among 235 eyes from 145 patients, 195 treatment-na?ve eyes were divided into no DR, m... | ['Choroid', 'Diabetes Mellitus, Type 2', 'Diabetic Retinopathy', 'Disease Progression', 'Female', 'Fluorescein Angiography', 'Humans', 'Macular Edema', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Republic of Korea', 'Retina', 'Retrospective Studies', 'Severity of Illness Index', 'Tomography, Optical Coherence... | 23,611,988 | [['A09.371.894.223'], ['C18.452.394.750.149', 'C19.246.300'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['C23.550.291.656'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439.245'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Management of condylomata acuminata with the carbon dioxide laser. | Ninety-four patients with condylomata acuminata of the lower genital tract and perianal region were treated with the carbon dioxide laser. Most were managed in the outpatient clinic, but 1 to 4 treatments were required depending upon extent of involvement. Of 90 patients, 75 (83.3%) were free of lesions on all follow-u... | ['Adolescent', 'Adult', 'Anus Neoplasms', 'Carbon Dioxide', 'Condylomata Acuminata', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Laser Therapy', 'Middle Aged', 'Uterine Cervical Neoplasms', 'Vaginal Neoplasms', 'Vulvar Neoplasms'] | 6,804,894 | [['M01.060.057'], ['M01.060.116'], ['C04.588.274.476.411.307.790.040', 'C06.301.371.411.307.790.040', 'C06.405.249.411.307.790.040', 'C06.405.469.491.307.790.040', 'C06.405.469.860.101.163', 'C06.405.469.860.180.500.040'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['C01.221.812.640.220', 'C01.778.640.220', 'C0... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex. | The cadherin/catenins complex regulates cell-cell adhesion and motility and is believed to have an invasion suppressor role. Primary mucoepidermoid carcinoma of the thyroid (MECT) is a rare tumour characterised by a distinct morphological appearance and a questionable histogenesis. The coexistence of papillary thyroid ... | ['Adolescent', 'Adult', 'Aged', 'Cadherins', 'Carcinoma, Mucoepidermoid', 'Child', 'Cytoskeletal Proteins', 'Desmoplakins', 'Female', 'Gene Expression', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Polymorphism, Single-Stranded Conformational', 'Thyroid Neoplasms', 'Trans-Activ... | 12,021,924 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.557.470.200.025.340', 'C04.557.470.590.340'], ['M01.060.406'], ['D12.776.220'], ['D12.776.220.790.500'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.22... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The relationship of Irgarol and its major metabolite to resident phytoplankton communities in a Maryland marina, river and reference area. | The objectives of this study were to: (1) measure water column concentrations of Irgarol 1051 and its major metabolite GS26575 annually (2004-2006) during mid-June and mid-August at 14 sites in a study area comprised of three sub-regions chosen to reflect a gradient in Irgarol exposure (Port Annapolis marina, Severn Ri... | ['Biomass', 'Chlorophyll', 'Chlorophyll A', 'Environmental Monitoring', 'Maryland', 'Photosynthesis', 'Phytoplankton', 'Risk Assessment', 'Rivers', 'Triazines'] | 19,296,991 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D03.383.129.578.840.374.140', 'D03.633.400.909.374.140', 'D04.345.783.374.140'], ['N06.850.460.350.080', 'N06.850.780.375'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['G02.111.158.937', '... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Manganese-induced NF-kappaB activation and nitrosative stress is decreased by estrogen in juvenile mice. | Manganese toxicity can cause a neurodegenerative disorder affecting cortical and basal ganglia structures with a neurological presentation resembling features of Parkinson's disease. Children are more sensitive to Mn-induced neurological dysfunction than adults, and recent studies from our laboratory revealed a marked ... | ['Animals', 'Apoptosis', 'Astrocytes', 'Cells, Cultured', 'Coculture Techniques', 'Dopamine', 'Estradiol', 'Female', 'Fluorescent Antibody Technique', 'Gene Expression Regulation', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Male', 'Manganese', 'Manganese Poisoning', 'Mice', 'Mice, Transgenic', 'Microglia', 'Mode... | 21,512,103 | [['B01.050'], ['G04.146.954.035'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['E05.481.500.374'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Unravelling the mechanism of action of enzyme replacement therapy in Fabry disease. | Fabry disease (FD) is a rare X-linked recessive glycosphingolipid-storage disorder caused by deficient activity of the lysosomal enzyme alpha-galactosidase A. Intravenous enzyme replacement therapy (ERT) has been used to supplement deficient enzyme activity in patients with FD. Despite its clinical effect and manifesta... | ['Adolescent', 'Adult', 'Enzyme Replacement Therapy', 'Fabry Disease', 'Female', 'Gene Expression Regulation', 'Gene Regulatory Networks', 'Humans', 'Male', 'Sex Factors', 'Transcriptome', 'Young Adult'] | 26,490,183 | [['M01.060.057'], ['M01.060.116'], ['E02.319.353.500'], ['C10.228.140.163.100.435.825.200', 'C10.228.140.300.275.374', 'C14.907.253.329.374', 'C16.320.322.124', 'C16.320.565.189.435.825.200', 'C16.320.565.398.641.803.300', 'C16.320.565.595.554.825.200', 'C18.452.132.100.435.825.200', 'C18.452.584.687.803.300', 'C18.452... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cyclic hair-loss and regrowth in transgenic mice overexpressing an intermediate filament gene. | We have produced transgenic mice containing up to 250 copies of a sheep wool intermediate filament keratin gene to study the effect of its expression on hair structure and development. Several transgenic lines expressed the gene and in the one containing 250 transgenes, a pattern of hair-loss and regrowth was stably es... | ['Amino Acids', 'Animals', 'Hair', 'Intermediate Filament Proteins', 'Keratins', 'Mice', 'Mice, Transgenic', 'Microscopy, Electron', 'Mutation', 'Nucleic Acid Hybridization', 'RNA Probes', 'Restriction Mapping', 'Sheep', 'Wool'] | 1,691,707 | [['D12.125'], ['B01.050'], ['A17.360'], ['D05.750.078.593', 'D12.776.220.475'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['E01.370.350.515.402', 'E05.595.402'], ['G05.365.590'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Two cases of Lactobacillus rhamnosus infection and pancreatitis]. | Lactobacilli rhamnosus infections are rare and occur in patients with severe conditions causing immunosuppression and/or in those who have received intense antibiotic treatment such as with teicoplanin and vancomycin. We report two cases which occurred within a period of 48 hours, during regression of pancreatitis in t... | ['Adult', 'Aged', 'Antidepressive Agents', 'C-Reactive Protein', 'Depression', 'Female', 'Gram-Positive Bacterial Infections', 'Humans', 'Lactobacillus rhamnosus', 'Pancreatitis'] | 18,096,340 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.427.700.122'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['F01.145.126.350'], ['C01.150.252.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475.700', 'B03.510.460.400.410.475.475.700', 'B03.510.550.450.475.700'], ['C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Living with incomprehensible fatigue after recent myocardial infarction. | AIM: This paper is a report of a study of what fatigue means to patients with recent myocardial infarction (MI) and how they manage to deal with the consequences of this symptom.BACKGROUND: After MI, fatigue is a frequent and distressing symptom. In nursing practice and in everyday conversations, the term 'tiredness' h... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Fatigue', 'Female', 'Hospitals, Rural', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Quality of Life', 'Severity of Illness Index', 'Stress, Psychological', 'Surveys and Questionnaires', 'Time Factors'] | 19,146,515 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['C23.888.369'], ['N02.278.421.518'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.308.9... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Neuro-oncology perspective of treatment options in metastatic breast cancer. | Breast cancer (BC) is a heterogeneous disease. Different subtypes of BC exhibit a peculiar natural history, metastatic potential and outcome. Stereotactic radiosurgery is the most used treatment for brain metastases (BM), while surgery is reserved for large and symptomatic lesions. Whole-brain radiotherapy is employed ... | ['Brain Neoplasms', 'Breast Neoplasms', 'Cranial Irradiation', 'Female', 'Humans', 'Neuroprotective Agents', 'Prognosis', 'Quality of Life', 'Radiosurgery'] | 29,956,562 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.588.180', 'C17.800.090.500'], ['E02.815.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['E01.789'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E02.815.530', 'E04.525.800.650',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
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