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Intergenerational Patterns of Smoking and Nicotine Dependence Among US Adolescents. | OBJECTIVES: We examined associations between parental and adolescent smoking and nicotine dependence in the United States.METHODS: We used data from the 2004 to 2012 National Survey on Drug Use and Health, which ascertained smoking behaviors of 1 parent and 1 adolescent aged 12 to 17 years in 35 000 dyads. We estimated... | ['Adolescent', 'Adolescent Behavior', 'Adult', 'Child', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Mental Health', 'Middle Aged', 'Odds Ratio', 'Parents', 'Smoking', 'Socioeconomic Factors', 'Tobacco Use Disorder', 'United States'] | 26,378,847 | [['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['M01.060.406'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['M01.060.116.630'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.830.600.600'], ['F01.829.263.500.3... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
First clinical tests using a liquid-filled electronic portal imaging device and a convolution model for the verification of the midplane dose. | BACKGROUND AND PURPOSE: Recently, algorithms have been developed to derive the patient dose from portal dose measurements using a liquid-filled electronic portal imaging device. These algorithms have already been validated for several phantom geometries irradiated under clinical conditions. It is the aim of the present... | ['Algorithms', 'Female', 'Humans', 'Male', 'Neoplasms', 'Phantoms, Imaging', 'Radiation Oncology', 'Radiography', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Reproducibility of Results', 'Scattering, Radiation'] | 9,681,895 | [['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E07.671'], ['H02.403.429.515.500', 'H02.403.740.650'], ['E01.370.350.700'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Lymphocyte cell lines from vitamin D-dependent rickets type II show functional defects in the 1 alpha,25-dihydroxyvitamin D3 receptor. | Lymphocyte cell lines were established from five patients with vitamin D-dependent rickets, type II (VDDR-II). These lines were established by infection with human T-lymphotrophic virus type I (HTLV-I). Binding of [3H]1 alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) to its receptor in these cell lines was compared to bindi... | ['24,25-Dihydroxyvitamin D 3', 'Calcitriol', 'Cell Line', 'Centrifugation, Density Gradient', 'Child, Preschool', 'Chromatography, DEAE-Cellulose', 'Female', 'Humans', 'Infant', 'Lymphocytes', 'Male', 'Proto-Oncogenes', 'RNA, Messenger', 'Receptors, Calcitriol', 'Receptors, Steroid', 'Rickets', 'T-Lymphocytes'] | 2,160,380 | [['D04.210.500.247.222.159.478.387.400', 'D04.210.500.247.808.146.478.387.400', 'D04.210.500.812.768.196.478.387.400', 'D10.570.938.146.478.387.400'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['A11.251.210'], ['... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The determination of the partial 18 S ribosomal DNA sequences of Cordyceps species. | Cordyceps species, which are used in Chinese traditional medicines, are fungal parasites of insects. In this study the partial nucleotide sequences of 18 S ribosomal DNA from four Cordyceps species were determined and compared with the sequences of published ascomycetes. The sequence data support the concept that Cordy... | ['Animals', 'Ascomycota', 'Base Sequence', 'DNA Primers', 'DNA, Fungal', 'DNA, Ribosomal', 'Hypocreales', 'Insecta', 'Medicine, Chinese Traditional', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 18S', 'Sequence Homology, Nucleic Acid', 'Species Specificity'] | 9,351,269 | [['B01.050'], ['B01.300.107'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.300'], ['D13.444.308.475'], ['B01.300.107.501'], ['B01.050.500.131.617'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['L01.453.245.667'], ['G05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Murine remote ischemic preconditioning suppresses diabetic ketoacidosis by enhancing glycolysis and entry into tricarboxylic acid cycle in the liver. | AIMS: Hindlimb ischemia-reperfusion (IR) was previously demonstrated by our group to decrease blood sugar levels by suppressing hepatic gluconeogenesis and enhancing glucose uptake using activation of the parasympathetic nervous system. While IR attenuated hyperglycemia in diabetic mice, it was unclear whether IR regul... | ['Animals', 'Blood Glucose', 'Citric Acid Cycle', 'Diabetes Mellitus, Experimental', 'Diabetic Ketoacidosis', 'Energy Metabolism', 'Fatty Acids', 'Glycolysis', 'Ischemic Preconditioning', 'Ketone Bodies', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Streptozocin'] | 32,387,415 | [['B01.050'], ['D09.947.875.359.448.500'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['G03.295'], ['D10.251'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['E02.59... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum amyloid P component binds to histones and activates the classical complement pathway. | Two members of the pentraxin family of proteins, C-reactive protein (CRP) and serum amyloid P component (SAP), bind to chromatin and may be involved in the solubilization and clearance of nuclear material. Previous studies demonstrated that CRP binding to chromatin is mediated by histones. SAP differs from CRP in being... | ['Animals', 'Binding, Competitive', 'C-Reactive Protein', 'Complement C1q', 'Complement C4', 'Complement Pathway, Classical', 'Histones', 'Humans', 'In Vitro Techniques', 'Protein Binding', 'Serum Amyloid P-Component'] | 1,431,140 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D12.776.124.486.274.050.270'], ['D12.776.124.486.274.350'], ['G12.274.698'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monkeys represent others' knowledge but not their beliefs. | The capacity to reason about the false beliefs of others is classically considered the benchmark for a fully fledged understanding of the mental lives of others. Although much is known about the developmental origins of our understanding of others' beliefs, we still know much less about the evolutionary origins of this... | ['Animals', 'Attention', 'Biological Evolution', 'Cognition', 'Humans', 'Macaca mulatta', 'Theory of Mind', 'Time Factors', 'Video Recording'] | 22,010,899 | [['B01.050'], ['F02.830.104.214'], ['G05.045', 'G16.075'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['F02.463.689', 'F02.739.897'], ['G01.910.857'], ['L01.280.960']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Implementation and Operational Research: Programmatic Feasibility of Dried Blood Spots for the Virological Follow-up of Patients on Antiretroviral Treatment in Nord Kivu, Democratic Republic of the Congo. | BACKGROUND: As part of its policy to shift monitoring of antiretroviral therapy (ART) to primary health care (PHC) workers, the Ministry of Health of the Democratic Republic of Congo (DRC) tested the feasibility of using dried blood spots (DBS) for viral load (VL) quantification and genotypic drug resistance testing in... | ['Adult', 'Anti-Retroviral Agents', 'Antiretroviral Therapy, Highly Active', 'Blood', 'Democratic Republic of the Congo', 'Dried Blood Spot Testing', 'Drug Resistance, Viral', 'Female', 'Follow-Up Studies', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'Operations Research', 'Viral Load'] | 26,413,848 | [['M01.060.116'], ['D27.505.954.122.388.077'], ['E02.319.310.075'], ['A12.207.152', 'A15.145'], ['Z01.058.290.100.220'], ['E01.370.225.124.100.232', 'E05.200.124.100.232'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Presence of NK2 binding sites in the rat brain. | Attempts were made to label tachykinin NK2 binding sites in the adult rat brain using [125I]neurokinin A (NKA) as ligand in the presence of NK1 and NK3 agonist or antagonist to avoid labelling of NK1 and NK3 binding sites, respectively. A high-affinity, specifically NK2-sensitive, [125I]NKA-binding, temperature-depende... | ['Animals', 'Autoradiography', 'Binding Sites', 'Brain Chemistry', 'Chromatography, High Pressure Liquid', "Guanosine 5'-O-(3-Thiotriphosphate)", 'In Vitro Techniques', 'Ligands', 'Male', 'Membranes', 'Neurokinin A', 'Peripheral Nervous System', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Neurokinin-2', 'Receptors, Neu... | 11,739,610 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G02.111.570.120'], ['G02.111.150', 'G03.185'], ['E05.196.181.400.300'], ['D02.886.765.380', 'D13.695.667.454.504.380', 'D13.695.827.426.504.380', 'D13.695.900.380'], ['E05.481'], ['D27.720.470.480'], ['A10.615'], ['D12.644.276.812.900.500', 'D12... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phenolic acids from beer are absorbed and extensively metabolized in humans. | In spite of the wide literature describing the biological effects of phenolic compounds, scarce data are available on their absorption from diet. In the present work, we studied the absorption in humans of phenolic acids from beer, a common beverage rich in different phenolic acids with related chemical structures. Bee... | ['Absorption', 'Adult', 'Beer', 'Caffeic Acids', 'Coumaric Acids', 'Female', 'Humans', 'Hydroxybenzoates', 'Male'] | 16,242,314 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.116'], ['G07.203.100.100.200', 'G07.203.200.250', 'J02.200.100.200', 'J02.350.250'], ['D02.241.223.200.054'], ['D02.241.223.200.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.300', 'D02.241.511.390', 'D02.455.426.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Beta-blocker therapy for heart failure: should the therapeutic target be dose or heart rate reduction? | Therapeutic target with beta blockers in heart failure, i.e., target heart rate reduction or beta-blocker dose, is controversial. To resolve this controversy, the authors studied 152 heart failure patients on beta blockers who were divided into four groups based on median peak exercise heart rate reduction as compared ... | ['Adrenergic beta-Antagonists', 'Carbazoles', 'Carvedilol', 'Female', 'Heart Failure', 'Heart Rate', 'Humans', 'Male', 'Metoprolol', 'Middle Aged', 'Propanolamines', 'Survival Rate', 'Treatment Outcome'] | 16,894,279 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['D03.633.100.473.144', 'D03.633.300.148'], ['D02.033.100.624.151', 'D02.033.755.624.151', 'D02.092.063.624.151', 'D03.633.100.473.144.125', 'D03.633.300.148.125'], ['C14.280.434'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of extended prostate biopsy including apical anterior region for cancer detection and prediction of surgical margin status for radical prostatectomy. | Objectives: We investigated diagnostic yield of initial biopsy and repeated biopsy including apical cores.Methods: We investigated 573 consecutive men with PSA of ?20 ng/ml who underwent prostate biopsy between 2004 and 2013. The initial 14-core biopsy consisted of the sextant type, lateral sites at the base and middle... | ['Aged', 'Biopsy', 'Humans', 'Male', 'Margins of Excision', 'Middle Aged', 'Prostate', 'Prostatectomy', 'Prostatic Neoplasms'] | 28,369,498 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.830', 'C23.149.625'], ['M01.060.116.630'], ['A05.360.444.575', 'A10.336.707'], ['E04.950.774.860.625... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Place of culdocentesis in the diagnosis of ectopic pregnancy. | In developing countries the high incidence of anaemia and pelvic infection often makes the diagnosis of ectopic pregnancy difficult. Culdocentesis has been used in 100 doubtful cases out of 144 consecutive cases of ectopic pregnancy. The preoperative diagnosis was correct in 93 out of the 100 cases. There were three fa... | ['Adult', 'Blood Transfusion', 'Drainage', 'Female', 'Hemorrhage', 'Humans', 'Maternal Mortality', 'Methods', 'Pregnancy', 'Pregnancy, Ectopic', 'Shock, Hemorrhagic', 'Vagina'] | 5,412,946 | [['M01.060.116'], ['E02.095.135'], ['E02.309', 'E04.237'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.500', 'N01.224.935.698.653', 'N06.850.505.400.975.550.500', 'N06.850.520.308.985.550.500'], ['E05.581'], ['G08.686.784.769'], ['C13.703.733'], ['C23.550.414.980', 'C23.550.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Invariant NKT cells suppress CD8(+) T-cell-mediated allergic contact dermatitis independently of regulatory CD4(+) T cells. | Invariant natural killer T (iNKT) cells expressing a CD1d-restricted invariant áâTCR have key regulatory roles in autoimmunity, pathogen immunity, and tumor surveillance, but their function in the control of allergic skin diseases remains poorly documented. Using a model of contact hypersensitivity (CHS) to the hapten ... | ['Animals', 'Antigens, CD1d', 'CD4 Antigens', 'CD8-Positive T-Lymphocytes', 'Cell Communication', 'Cells, Cultured', 'Coculture Techniques', 'Dermatitis, Allergic Contact', 'Down-Regulation', 'Female', 'Flow Cytometry', 'Forkhead Transcription Factors', 'Interferon-gamma', 'Interleukin-13', 'Interleukin-4', 'Mice', 'Mi... | 23,190,881 | [['B01.050'], ['D23.050.301.264.035.100.500', 'D23.050.301.264.894.080.500', 'D23.101.100.110.100.500', 'D23.101.100.894.080.500'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genomic analysis of HAdV-B14 isolate from the outbreak of febrile respiratory infection in China. | Human adenovirus type 14 (HAdV-B14) was first reported in 1955 from the Netherlands and since then had been associated with outbreaks of febrile respiratory illness (FRI). In China, sporadic HAdV-B14 infections were first identified in 2010, in Guangzhou and Beijing. In 2012, an outbreak of FRI occurred in Beijing and ... | ['Adenovirus Infections, Human', 'Adenoviruses, Human', 'China', 'Disease Outbreaks', 'Fever', 'Genes, Viral', 'Genome, Viral', 'Humans', 'Phylogeny', 'Polymerase Chain Reaction', 'Respiratory Tract Infections', 'Sequence Analysis, DNA', 'Sequence Homology', 'United States'] | 24,055,951 | [['C01.925.256.076.045'], ['B04.280.030.500.350'], ['Z01.252.474.164'], ['N06.850.290'], ['C23.888.119.344'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.... | ['Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Clinical aspects of the SR-IV Programmed Subjective Refractor. | Five studies were performed on 682 eyes of currently working and retired factory workers and some of their children. The magnitude of the refractive error and the visual acuity obtained were essentially equivalent for the two methods (SR-IV, Phoroptor). SR-IV testing required less time than conventional techniques. Pat... | ['Accommodation, Ocular', 'Adolescent', 'Adult', 'Aged', 'Child', 'Humans', 'Middle Aged', 'Ophthalmology', 'Optometry', 'Refraction, Ocular', 'Refractive Errors'] | 7,148,974 | [['G14.010'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.403.810.468'], ['H02.553'], ['E01.370.380.850.700', 'G01.590.775', 'G14.760'], ['C11.744']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Human immunodeficiency virus type 1 population bottleneck during indinavir therapy causes a genetic drift in the env quasispecies. | The impact of emergence of genetic resistance, soon after the beginning of antiretroviral therapy, on the genotype of other viral loci not implicated in the development of resistance was studied in four human immunodeficiency type 1 (HIV-1)-infected patients subjected to indinavir monotherapy. Two patients were chosen ... | ['Amino Acid Sequence', 'Cloning, Molecular', 'Drug Resistance, Microbial', 'Evolution, Molecular', 'Gene Frequency', 'Genes, env', 'HIV Envelope Protein gp120', 'HIV Infections', 'HIV Protease', 'HIV Protease Inhibitors', 'HIV-1', 'Humans', 'Indinavir', 'Molecular Sequence Data', 'Peptide Fragments', 'Reverse Transcri... | 10,640,545 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['G06.225', 'G07.690.773.984.269'], ['G05.045.250', 'G16.075.250'], ['G05.330'], ['G05.360.340.024.340.364.875.172', 'G05.360.340.358.024.875.172', 'G05.360.340.358.840.500.172'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.776.964.97... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Medicaid program: payment for long-term care facility services and inpatient hospital services--Health Care Financing Administration. Interim final rule with comment period. | We are revising the regulations on Medicaid payment for long-term care (LTC) facility and inpatient hospital services. Revised regulations are needed to implement recent amendments to the Medicaid law (section 962 of the Omnibus Reconciliation Act of 1980 and section 2173 of the Omnibus Budget Reconciliation Act of 198... | ['Fees and Charges', 'Medicaid', 'Reimbursement Mechanisms', 'United States'] | 10,298,296 | [['N03.219.442'], ['N03.219.521.346.506.564.655', 'N03.706.615.693'], ['N03.219.521.710.305'], ['Z01.107.567.875']] | ['Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Corpus albicans-like structures in the gonads in androgen insensitivity syndrome. | The complete androgen insensitivity syndrome is the most common form of male pseudohermaphroditism and is due to end-organ unresponsiveness to androgens. The patients are phenotypically female, but the genotype is 46, XY, and the gonads are testicles. However, the common presence of Sertoli cell adenomalike nodules of ... | ['Adult', 'Androgen-Insensitivity Syndrome', 'Androgens', 'Disorders of Sex Development', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Phenotype', 'Seminiferous Tubules', 'Testis'] | 8,786,209 | [['M01.060.116'], ['C12.706.316.096.500', 'C13.351.875.253.096.500', 'C16.131.939.316.096.500', 'C16.320.322.061', 'C19.391.119.096.500'], ['D27.505.696.399.472.161'], ['C12.706.316', 'C13.351.875.253', 'C16.131.939.316', 'C19.391.119'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.75... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Moderate supplementation of potassium in essential hypertension]. | 23 unselected patients with mild to moderate essential hypertension, whose average supine blood pressure after two months' observation on no treatment was 154/99 mm Hg, were entered into an eight week double blind randomised crossover study of one month's treatment with slow release potassium tablets (60 mmol/day) vers... | ['Adult', 'Aged', 'Clinical Trials as Topic', 'Delayed-Action Preparations', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Potassium', 'Tablets'] | 6,428,368 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fetal expression of muscle-specific isoactins in multiple organs of the Wistar-Kyoto rat. | Actin, a cytoskeletal and contractile protein, is expressed in six different isoforms that exhibit striking specificity. No studies have considered the muscle-specific actin expression in multiple organ systems in the intact fetus. Using a monoclonal antibody (B4) which reacts specifically with the isoactins of the smo... | ['Actins', 'Animals', 'Digestive System', 'Fetus', 'Gestational Age', 'Heart', 'Kidney', 'Lung', 'Muscle, Smooth, Vascular', 'Muscles', 'Organ Specificity', 'Rats', 'Rats, Inbred WKY'] | 3,652,167 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['A03'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['A07.541'], ['A05.810.453'], ['A04.411'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['A02.633', 'A10.690'], ['G07.650'], ['B01.050.150.900.649.313.992.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The hygienic toxicological evaluation of the viral preparation Mamestrin]. | The preparation "Mamestrine" developed in Bulgaria on the basis of NPV virus is meant for control of the Heliothis zea. Experiments are carried out on the toxic effect of the preparation, according to the requirements of FAO/WHO for assessment of the virus preparations and the acting in this country Bulgarian State Sta... | ['Animals', 'Baculoviridae', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Female', 'Guinea Pigs', 'Haplorhini', 'Humans', 'Insecticides', 'Male', 'Rabbits', 'Rats', 'Tumor Cells, Cultured'] | 1,796,114 | [['B01.050'], ['B04.280.065', 'B04.525.100'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.031.700.491', 'D27.888.723.491'], ['B01.050.150.900.649.313.968.700'], ['B01.050.150.900... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A plant growth promoting rhizobacterium, Paenibacillus polymyxa strain GBR-1, suppresses root-knot nematode. | Exposure of root-knot nematode, Meloidogyne incognita to various concentrations (5-100%) of culture filtrate of Paenibacillus polymyxa GBR-1 under in vitro conditions significantly reduced egg hatch and caused substantial mortality of its juveniles. The increase in the exposure durations of juveniles to culture filtrat... | ['Animals', 'Panax', 'Plant Diseases', 'Plant Growth Regulators', 'Plant Roots', 'Rhizobium', 'Tylenchoidea'] | 17,706,411 | [['B01.050'], ['B01.650.940.800.575.912.250.087.500'], ['G15.610'], ['D27.505.696.377.760'], ['A18.400'], ['B03.440.400.425.700.800', 'B03.585.900', 'B03.660.050.662.670'], ['B01.050.500.500.294.400.984.825']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two-phase thermophilic anaerobic digestion process for biohythane production treating biowaste: preliminary results. | This paper deals with the optimization of a two-phase anaerobic process treating biowaste for hydrogen and methane production. Neither physical nor chemical pre-treatments were used to optimize the process. The work was carried out at pilot scale, using two CSTRs (200 and 380 L working volume respectively) both maintai... | ['Anaerobiosis', 'Biofuels', 'Medical Waste Disposal', 'Sewage', 'Temperature'] | 22,097,052 | [['G02.111.062', 'G03.078'], ['D20.147', 'N06.230.132.644.124'], ['D20.944.460.300', 'N06.850.460.710.460.300', 'N06.850.860.510.900.600.600'], ['D20.944.932.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Circulating tumor cells and "suspicious objects" evaluated through CellSearch® in metastatic renal cell carcinoma. | BACKGROUND: Recent evidence supports the hypothesis that the CellSearch assay, used in the enumeration of circulating tumor cells (CTCs), may underestimate the number of CTCs, especially in tumors, such as renal cell carcinoma, frequently lacking cytokeratin expression. According to the CellSearch guidelines, all objec... | ['Aged', 'Carcinoma, Renal Cell', 'Cytological Techniques', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Hyaluronan Receptors', 'Keratin-18', 'Keratin-19', 'Keratin-8', 'Kidney Neoplasms', 'Medical Oncology', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplastic Cells, Circulating', 'Reproducibility of Results'] | 22,199,284 | [['M01.060.116.100'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.735.200.625', 'D12.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Retention of configuration in the action of human plasma 3'-exonuclease on oligo(deoxynucleoside phosphorothioate). A new method for assignment of absolute configuration at phosphorus in isotopomeric deoxyadenosine 5'-O-[(18)O]phosphorothioate. | A new method of analysis has allowed the exonucleolytic cleavage by human 3'-exonuclease to be determined. Hydrolysis by human plasma 3'-exonuclease proceeds with retention of configuration at phosphorus. The new method determines the sense of chirality at phosphorus in isotopomeric adenosine 5'-O-[(18)O]phosphorothioa... | ['Deoxyadenosines', 'Exonucleases', 'Humans', 'Molecular Conformation', 'Phosphorus', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Thionucleotides'] | 11,971,710 | [['D03.633.100.759.590.138.325', 'D13.570.230.229', 'D13.570.583.138.325'], ['D08.811.277.352.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820'], ['D01.268.666'], ['E05.196.566.755'], ['D02.886.765', 'D13.695.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New evidence on controlling alcohol use through price. | A problem in earlier studies of the demand for beer, wine and distilled spirits was determining the effect on one category of alcoholic beverage of price changes in other categories. The present study estimates the demand for all alcoholic beverages, finding a stable relationship over a 40-year period. Policy implicati... | ['Alcohol Drinking', 'Alcoholic Beverages', 'Alcoholism', 'Costs and Cost Analysis', 'Financing, Personal', 'Humans', 'Public Policy', 'United States'] | 6,664,090 | [['F01.145.317.269'], ['G07.203.100.100', 'J02.200.100'], ['C25.775.100.250', 'F03.900.100.350'], ['N03.219.151'], ['N03.219.559'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer. | Polycyclic aromatic hydrocarbons (PAH) are mammary carcinogens in animal studies, and a few epidemiologic studies have suggested a link between elevated levels of PAH-DNA adducts and breast cancer incidence. An association between PAH-DNA adducts and survival among breast cancer cases has not been previously reported. ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Carcinogens, Environmental', 'Case-Control Studies', 'DNA Adducts', 'Female', 'Humans', 'Incidence', 'Middle Aged', 'Outcome Assessment, Health Care', 'Polycyclic Aromatic Hydrocarbons', 'Predictive Value of Tests', 'Proportional Hazards Models', 'Survival Ana... | 19,181,313 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['D27.888.569.100.125'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D13.444.308.135', 'G05.200.104'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N0... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The case against 'pot'. | There has been much ill-informed debate about cannabis and the fallacy has come to be accepted that little or nothing of scientific value is known about the effects of the drug. This paper presents definitive evidence concerning the hazards of cannabis use, particularly in terms of intoxication effects, driving hazards... | ['Aggression', 'Animals', 'Australia', 'Automobile Driving', 'Cannabis', 'Dronabinol', 'Humans', 'Legislation, Drug', 'Risk', 'Substance-Related Disorders'] | 588,151 | [['F01.145.126.125', 'F01.145.813.045'], ['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['I03.125'], ['B01.650.940.800.575.912.250.859.937.055.500'], ['D02.455.849.090.810'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.605', 'N03.706.615.402'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.75... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Variable responses of regional renal oxygenation and perfusion to vasoactive agents in awake sheep. | Vasoactive agents are used in critical care to optimize circulatory function, but their effects on renal tissue oxygenation in the absence of anesthesia remain largely unknown. Therefore, we assessed the effects of multiple vasoactive agents on regional kidney oxygenation in awake sheep. Sheep were surgically instrumen... | ['Angiotensin II', 'Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Arginine Vasopressin', 'Captopril', 'Female', 'Kidney', 'Norepinephrine', 'Oxygen Consumption', 'Sheep', 'Vasoconstrictor Agents'] | 26,354,843 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D27.505.519.389.745.085'], ['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical studies of stellate cells in experimental cholestasis in newborn and adult rats. | BACKGROUND AND AIMS: Although there is much known about liver diseases, some aspects remain unclear, such as the nature of the differences between the diseases observed in newborn infants and those in adults. For example, how do newborns respond to duct epithelial cell injury? Do the stellate cells in newborns respond ... | ['Actins', 'Age Factors', 'Animals', 'Animals, Newborn', 'Biliary Atresia', 'Biomarkers', 'Cholestasis', 'Desmin', 'Disease Models, Animal', 'Extracellular Matrix Proteins', 'Female', 'Fibroblasts', 'Hepatic Stellate Cells', 'Ligation', 'Male', 'Portal System', 'Rats', 'Rats, Wistar'] | 18,925,331 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.050.282'], ['C06.130.120.123', 'C06.198.125', 'C16.131.314.125'], ['D23.101'], ['C06.130.120.135'], ['D05.750.078.593.200', 'D12.776.220.475.200'], ['C22.232', 'E05.598.500', 'E05.599.3... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of the specificity and sensitivity of PCR, nested PCR, and real-time PCR for the diagnosis of histomoniasis. | Blackhead, also known as enterohepatitis, is caused by a protozoan parasite called Histomonas meleagridis. Clinical symptoms are nonspecific. Until now, diagnosis has been mainly based on postmortem lesions and microscopical and histopathological examination. In many cases, especially in layer flocks, these conventiona... | ['Amino Acid Sequence', 'Animals', 'Eukaryota', 'Polymerase Chain Reaction', 'Poultry Diseases', 'Protozoan Infections', 'Protozoan Infections, Animal', 'Protozoan Proteins', 'Sensitivity and Specificity', 'Sequence Homology, Amino Acid'] | 16,252,489 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01'], ['E05.393.620.500'], ['C22.131.728'], ['C01.610.752'], ['C01.610.701.688', 'C01.610.752.625', 'C22.674.710'], ['D12.776.820'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.85... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Approach of pharmacists and herbalists while offering guidance on potentially malignant oral lesions: a cross-sectional survey. | OBJECTIVES: To investigate the approach of both pharmacies and herbalists' shops while offering a proper advice for patients seeking guidance on a potentially malignant oral lesion.MATERIALS AND METHODS: A cross-sectional, descriptive study was undertaken using the standardized patient approach on a representative samp... | ['Consultants', 'Cross-Sectional Studies', 'Health Care Surveys', 'Humans', 'India', 'Mouth Neoplasms', 'Pharmacists', 'Surveys and Questionnaires'] | 25,313,749 | [['M01.120'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['C04.588.443.591', 'C07.465.530'], ['M01.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Diagnosing autism spectrum disorders in pre-school children using two standardised assessment instruments: the ADI-R and the ADOS. | The reliable diagnosis of Autism/Autism Spectrum Disorder in pre-school children is important for access to early intervention and for accurate ascertainment for research. This paper explores the combined use of two standardised assessment instruments--the Autism Diagnostic Interview Revised (ADI-R) and the Autism Diag... | ['Algorithms', 'Autistic Disorder', 'Child, Preschool', 'Communication', 'Diagnosis, Differential', 'Female', 'Humans', 'Language Development Disorders', 'Male', 'Patient Care Team', 'Personality Assessment', 'Psychometrics', 'Reproducibility of Results', 'Social Behavior', 'Stereotyped Behavior'] | 17,605,097 | [['G17.035', 'L01.224.050'], ['F03.625.164.113.500'], ['M01.060.406.448'], ['F01.145.209', 'L01.143'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.500.550', 'C23.888.592.604.150.500.550'], ['N04.590.715'], ['F04.513'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
An analysis of patient safety incidents associated with medications reported from critical care units in the North West of England between 2009 and 2012. | Incident reporting is promoted as a key tool for improving patient safety in healthcare. We analysed 2238 patient safety incidents involving medications submitted from up to 29 critical care units each year in the North West of England between 2009 and 2012; 452 (20%) of these incidents led to harm to patients. Althoug... | ['Critical Care', 'England', 'Health Care Surveys', 'Humans', 'Intensive Care Units', 'Medication Errors', 'Patient Safety', 'Safety Management'] | 24,810,765 | [['E02.760.190', 'N02.421.585.190'], ['Z01.542.363.300'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E02.319.529', 'N02.421.450.500'], ['N06.850.135.060.075.399'], ['N04.452.871.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The influence of diethylmaleate on the biliary excretion of infused sulphobromophthalein sodium and its glutathione conjugate in guinea-pigs. | 1. Hepatic sulphobromophthalein (BSP) transport was studied in guinea-pigs pretreated intraperitoneally with 0.7 ml of diethyl maleate to depress hepatic glutathione levels. 2. Diethyl maleate depressed the hepatic transport of infused conjugated BSP from hepatocytes into bile without influencing hepatic uptake. 3. Unc... | ['Animals', 'Bile', 'Female', 'Glutathione', 'Guinea Pigs', 'Liver', 'Maleates', 'Sulfobromophthalein'] | 7,249,400 | [['B01.050'], ['A12.200.087'], ['D12.644.456.448'], ['B01.050.150.900.649.313.992.550'], ['A03.620'], ['D02.241.081.337.502'], ['D02.455.426.559.389.657.625.617']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PKG II inhibits EGF/EGFR-induced migration of gastric cancer cells. | BACKGROUND: Our previous research results showed that Type II cGMP dependent protein kinase (PKG II) could block the activation of epidermal growth factor receptor (EGFR) and consequently inhibit the proliferation and the related MAPK/ERK-mediated signal transduction of gastric cancer cell line BGC-823, suggesting that... | ['Cell Line', 'Cell Line, Tumor', 'Cell Movement', 'Cyclic GMP', 'Cyclic GMP-Dependent Protein Kinase Type II', 'Epidermal Growth Factor', 'ErbB Receptors', 'Humans', 'Phosphorylation', 'Signal Transduction', 'Stomach Neoplasms', 'Thionucleotides'] | 23,613,900 | [['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D08.811.913.696.620.682.700.150.150.750', 'D12.644.360.200.150.750', 'D12.776.476.200.150.750'], ['D06.472.317.350', 'D12.644.276.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Frequency selectivity of the normal guinea pig cochlea and in experimental hearing loss]. | The frequency selectivity of the cochlea was measured in pigmented guinea pigs with implanted electrodes using simultaneous masking paradigm. In animals with experimentally induced deafness, AP tuning curves are broadened by a factor of 2-3 as compared with normal animals. The deterioration of frequency selectivity is ... | ['Acoustic Stimulation', 'Action Potentials', 'Animals', 'Auditory Threshold', 'Cochlea', 'Evoked Potentials, Auditory', 'Guinea Pigs', 'Hair Cells, Auditory', 'Hearing Loss, Sensorineural', 'Kanamycin', 'Vestibulocochlear Nerve'] | 3,996,676 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['A09.246.300.246'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['B01.050.150.900.649.313.992.550'], ['A08.675.650.25... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The N2N instrument to evaluate healthy work environments: an Italian validation. | OBJECTIVES: The aims of the study were to (a) validate N2N Healthy Work Environment tool, (b) assess the healthiness of work environments as perceived by nurses themselves and (c) identify the factors associated with Italian nurses' perception of work environment healthiness.METHODS: The linguistic and cultural adaptat... | ['Adult', 'Factor Analysis, Statistical', 'Female', 'Hospitals', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Nurses', 'Occupational Health', 'Perception', 'Reproducibility of Results', 'Surveys and Questionnaires', 'Translating', 'Workplace', 'Young Adult'] | 23,423,280 | [['M01.060.116'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['M01.526.485.650', 'N02.360.650'], ['N01.400.525'], ['F02.463.593'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcome. | BACKGROUND: Elderly patients (age > or = 65 years) with acute myeloid leukemia (AML) generally have a poor prognosis. AML-type therapy results are often derived from studies in younger patients and may not apply to elderly AML. Many investigators and oncologists advocate, at times, only supportive care or frontline sin... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Leukemia, Myeloid', 'Male', 'Models, Theoretical', 'Myelodysplastic Syndromes', 'Prognosis', 'Retrospective Studies', 'Risk Factors'] | 16,435,386 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539'], ['E05.599'], ['C15.378.190.625'], ['E01.789'], ['E05.318.372.500... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Lead and cadmium toxicity in established mammalian cell lines]. | Lead and cadmium toxicity was evaluated in three mammalian cell lines (tumour : HeLa, transformed : XC and normal : NRK) by means of the modifications of the 3H-TdR incorporation rate in the nucleus of the treated cells. The three cell lines showed different degrees of sensitivity. Sensitivity depended on the line, met... | ['Cadmium', 'Cell Line', 'DNA', 'DNA Replication', 'HeLa Cells', 'Kinetics', 'Lead', 'Thymidine'] | 153,166 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['A11.251.210'], ['D13.444.308'], ['G02.111.225', 'G05.226'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G01.374.661', 'G02.111.490'], ['D01.268.556.435', 'D01.552.544.435'], ['D03.383.742.680.705', 'D13.570.230.855', 'D13.570.685.705']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Some dynamic aspects of hematopoietic stem cells. | Hematopoiesis is the process responsible for maintaining the number of circulating blood cells that are undergoing continuous turnover. At the root of this process are the hematopoietic stem cells (HSC). In the following we discuss various dynamic aspects of HSC behavior ranging from the number of active stem cells, th... | ['Animals', 'Cell Differentiation', 'Cell Lineage', 'Cell Proliferation', 'Hematologic Neoplasms', 'Hematopoiesis', 'Hematopoietic Stem Cells', 'Humans', 'Models, Biological'] | 18,176,847 | [['B01.050'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.448', 'C15.378.400'], ['G04.152.825', 'G09.188.343'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Systemwide effects of Medicaid retrospective drug utilization review programs. | Aggregate pooled cross-sectional and time-series annual state data for 1985 to 1992 were used to estimate the systemwide effects of retrospective drug utilization review programs (Retro-DUR) on Medicaid drug and nondrug outcomes. The results provide evidence that these programs produce significant cost savings in the d... | ['California', 'Cost Savings', 'Cross-Sectional Studies', 'Drug Utilization Review', 'Health Expenditures', 'Health Services Needs and Demand', 'Humans', 'Medicaid', 'Models, Econometric', 'Outcome Assessment, Health Care', 'Program Evaluation', 'Retrospective Studies', 'State Health Plans', 'United States'] | 10,979,516 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N03.219.151.160.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.452.706.477.400', 'N04.761.879.300', 'N05.700.900.300'], ['N03.219.151.450', 'N05.300.385'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.31... | ['Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Age-related increase in a cathepsin D like protease that degrades brain microtubule-associated proteins. | In microtubules isolated from brains of very old rats, two of the major microtubule-associated proteins, MAP1 and MAP2, are found only in degraded form. MAP1 is present as a piece whose molecular weight on sodium dodecyl sulfate-polyacrylamide gel electrophoresis is circa 50,000 smaller than the native protein, and MAP... | ['Aging', 'Animals', 'Brain', 'Cathepsin D', 'Microtubule-Associated Proteins', 'Microtubules', 'Peptide Hydrolases', 'Rats', 'Rats, Inbred Strains', 'Substrate Specificity'] | 3,327,517 | [['G07.345.124'], ['B01.050'], ['A08.186.211'], ['D08.811.277.656.074.500.180', 'D08.811.277.656.224.187', 'D08.811.277.656.300.048.180'], ['D12.776.220.600.450', 'D12.776.631.560'], ['A11.284.430.214.190.750.602'], ['D08.811.277.656'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Observations on the influence of water and soil pH on the persistence of insecticides. | The pH-disappearance rate profiles were determined at ca. 25 degrees C for 24 insecticides at 4 or 5 pH values over the range 4.5 to 8.0 in sterile phosphate buffers prepared in water-ethanol (99:1 v/v). Half-lives measured at pH 8 were generally smaller than at lower pH values. Changes in half lives between pH 8.0 and... | ['Half-Life', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Insecticides', 'Pesticide Residues', 'Soil', 'Water'] | 7,175,098 | [['G01.910.405'], ['G02.300'], ['G02.380'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.200.700'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The role of the micrographic surgery in the management of basal cell carcinoma: experience in the Department of Dermatology, at the Hassan II University Hospital, Fes, Morocco]. | Mohs micrographic surgery (MMS) is a technique allowing for intraoperative histologic assessment of surgical margin of malignant tumors. This study aims to highlight the role of MMS in the achievement of radical healing of basal cell carcinoma (BCC) in our patients. We conducted a study of 29 patients with basal cell c... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Basal Cell', 'Child', 'Facial Neoplasms', 'Female', 'Hospitals, University', 'Humans', 'Male', 'Margins of Excision', 'Middle Aged', 'Mohs Surgery', 'Morocco', 'Prospective Studies', 'Skin Neoplasms', 'Treatment Outcome', 'Young Adult'] | 31,692,779 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['M01.060.406'], ['C04.588.443.392'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.830', 'C23.149.625'], ['M01.060.116.630'], ['E04.4... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Relationships between strategy switching and strategy switch costs in young and older adults: a study in arithmetic problem solving. | UNLABELLED: BACKGROUND/STUDY CONTEXT: This study investigated age-related differences in within-item strategy switching (i.e., revising initial strategy choices to select a better strategy while solving a given problem) and in strategy switch costs (i.e., longer latencies when participants switch strategies than when t... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Executive Function', 'Female', 'Humans', 'Male', 'Mathematics', 'Middle Aged', 'Problem Solving', 'Young Adult'] | 25,724,013 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['M01.060.116.630'], ['F02.463.425.725', 'F02.463.785.810'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
How Accurately Do Consecutive Cohort Audits Predict Phase III Multisite Clinical Trial Recruitment in Palliative Care? | CONTEXT: Audits have been proposed for estimating possible recruitment rates to randomized controlled trials (RCTs), but few studies have compared audit data with subsequent recruitment rates.OBJECTIVES: To compare the accuracy of estimates of potential recruitment from a retrospective consecutive cohort audit of actua... | ['Anorexia', 'Australia', 'Clinical Audit', 'Delirium', 'Humans', 'Intestinal Diseases', 'Pain', 'Pain Management', 'Palliative Care', 'Patient Selection'] | 26,732,730 | [['C23.888.821.108'], ['Z01.639.100', 'Z01.678.100.373'], ['N04.761.700.250', 'N05.700.175'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.745', 'N0... | ['Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
EBNA2 interferes with the germinal center phenotype by downregulating BCL6 and TCL1 in non-Hodgkin's lymphoma cells. | Epstein-Barr virus (EBV)-negative diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma-derived cell lines infected in vitro with a recombinant EBV expressed type II/III latency. High expression of EBNA2 inversely correlated with expression of germinal center (GC)-associated genes, BCL6 and TCL1. The decreased exp... | ['Base Sequence', 'Burkitt Lymphoma', 'Cell Line, Tumor', 'DNA, Neoplasm', 'DNA-Binding Proteins', 'Down-Regulation', 'Epstein-Barr Virus Nuclear Antigens', 'Gene Expression', 'Genes, Viral', 'Germinal Center', 'HLA-DR Antigens', 'Herpesvirus 4, Human', 'Humans', 'Immunoglobulin M', 'Lymphoma, B-Cell', 'Lymphoma, Large... | 17,151,114 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['A11.251.210.190', 'A11.251.860.180'], ['D13.444.308.425'], ['D12.776.260'], ['G02.111.240', 'G05.308.200', 'G07.690.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reaction of optically active alpha-aminoallenylstannanes with aldehydes formed in situ from the Lewis-acid-catalyzed rearrangement of epoxides. | Reaction of optically active alpha-oxazolidinonylallenylstannanes with oxiranes in the presence of BF3.OEt2 produced beta-hydroxypropargylamines with high syn diastereoselectivity and high enantioselectivity through an initial Lewis-acid-catalyzed rearrangement of the oxirane to the corresponding aldehyde via an alkyl,... | ['Acids', 'Aldehydes', 'Amination', 'Catalysis', 'Epoxy Compounds', 'Ethylene Oxide', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Optical Rotation', 'Stereoisomerism', 'Tin Compounds'] | 16,050,728 | [['D01.029'], ['D02.047'], ['G02.111.053', 'G02.607.110', 'G03.068'], ['G02.130'], ['D02.355.291.411'], ['D02.355.291.411.417'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['G01.590.773'], ['G02.607.445.682'], ['D01.935']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of human trophoblast membrane antigens in maternal blood during pregnancy. | The development of an immunoradiometric assay for the detection of human trophoblast-specific membrane antigens is described. The test revealed for the first time circulating trophoblast-specific cell membrane antigens in the peripheral blood of pregnant women, but none in non-pregnant female or male controls. Comparis... | ['Antigens, Surface', 'Epitopes', 'Female', 'Fetal Blood', 'Humans', 'Male', 'Maternal-Fetal Exchange', 'Pre-Eclampsia', 'Pregnancy', 'Radioimmunoassay', 'Trophoblasts'] | 6,177,463 | [['D23.050.301'], ['D23.050.550'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.455'], ['C13.703.395.249'], ['G08.686.784.769'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['A11.382.992', 'A16.254.500.766', 'A16.710.802']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The survival of silage inoculant lactic acid bacteria in rumen fluid. | AIMS: To determine whether lactic acid bacteria (LAB) used in inoculants for silage can survive in rumen fluid (RF), and to identify those that survive best.METHODS AND RESULTS: Twelve commercial silage inoculants were added at 107 CFU ml-1 to strained RF (SRF) taken from dairy cows, with and without 5 g l-1 glucose an... | ['Animals', 'Bacteriological Techniques', 'Cattle', 'Fermentation', 'Lactobacillus', 'Probiotics', 'Rumen', 'Silage'] | 12,752,816 | [['B01.050'], ['E01.370.225.875.150', 'E05.200.875.150'], ['B01.050.150.900.649.313.500.380.271'], ['G02.111.158.249', 'G03.191.249'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['G07.203.300.456.500', 'J02.500.456.500'], ['A13.869.804'], ['G07.203.200.750', 'G07.203.300.300.100.800'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pigmented neuroectodermal tumour of infancy: an immunohistochemical study. | The pigmented neuroectodermal tumour of infancy is a rare neoplasm of uncertain histogenesis which, in the majority of cases, arises in the maxilla and pursues a benign course. Currently, it would be classified in the group of peripheral primitive neuroectodermal tumours. Histologically it is composed of two principal ... | ['Cell Differentiation', 'Female', 'Humans', 'Immunohistochemistry', 'Infant', 'Keratins', 'Male', 'Neoplasms, Germ Cell and Embryonal', 'Phosphopyruvate Hydratase', 'S100 Proteins', 'Vimentin'] | 2,453,438 | [['G04.152'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['M01.060.703'], ['D0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery. | A female aged 53 years was found to have a suprasellar lesion, which was shown to be a Rathke's cyst after removal by transsphenoidal surgery. She presented 16 days postoperatively, and following two grand mal seizures was found to be profoundly hyponatraemic (sodium 101 nmol/l). She was initially thought to have the s... | ['Brain', 'Brain Diseases, Metabolic', 'Craniopharyngioma', 'Female', 'Humans', 'Hyponatremia', 'Middle Aged', 'Pituitary Gland', 'Pituitary Neoplasms', 'Postoperative Complications', 'Sodium Chloride', 'Syndrome'] | 8,810,741 | [['A08.186.211'], ['C10.228.140.163', 'C18.452.132'], ['C04.557.465.625.200', 'C04.557.580.625.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.620'], ['M01.060.116.630'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.200.317.357.352.435.500', 'A08.713.357.750']... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Surgical resection of giant left ventricular fibromas in children. | Primary cardiac tumors in infancy and childhood are rare and usually benign. We report two children with giant left ventricular fibromas and discuss their surgical management. | ['Cardiac Surgical Procedures', 'Child', 'Female', 'Fibroma', 'Heart Neoplasms', 'Heart Ventricles', 'Humans', 'Male', 'Treatment Outcome'] | 28,929,583 | [['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['C04.557.450.565.590.340'], ['C04.588.894.309', 'C14.280.459'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Locally-delivered T-cell-derived cellular vehicles efficiently track and deliver adenovirus delta24-RGD to infiltrating glioma. | Oncolytic adenoviral vectors are a promising alternative for the treatment of glioblastoma. Recent publications have demonstrated the advantages of shielding viral particles within cellular vehicles (CVs), which can be targeted towards the tumor microenvironment. Here, we studied T-cells, often having a natural capacit... | ['Adenoviridae', 'Animals', 'Biological Therapy', 'Cell Line', 'Disease Models, Animal', 'Drug Delivery Systems', 'Female', 'Glioma', 'Humans', 'Mice', 'Oncolytic Viruses', 'Survival Analysis', 'T-Lymphocytes', 'Treatment Outcome'] | 25,118,638 | [['B04.280.030'], ['B01.050'], ['E02.095'], ['A11.251.210'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.300'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B04.700'], ['E05.318... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Autistic behavior in young boys with fragile X syndrome. | A sample of 57 boys with fragile X syndrome (fraX) between the ages of 24 and 133 months was rated using the Childhood Autism Rating Scale (CARS) to assess the extent to which autism and autistic features were evident in a young population. Fourteen subjects (approximately 25% of the sample) scored above the cutoff for... | ['Autistic Disorder', 'Child', 'Child, Preschool', 'Fragile X Syndrome', 'Humans', 'Infant', 'Male', 'Neuropsychological Tests', 'Psychometrics', 'Reproducibility of Results'] | 9,932,236 | [['F03.625.164.113.500'], ['M01.060.406'], ['M01.060.406.448'], ['C10.597.606.360.455.500', 'C16.131.260.830.300', 'C16.320.180.830.300', 'C16.320.322.500.500', 'C16.320.400.525.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F04.711.513'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', ... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Disability in two health care systems: access, quality, satisfaction, and physician contacts among working-age Canadians and Americans with disabilities. | BACKGROUND: An overarching question in health policy concerns whether the current mix of public and private health coverage in the United States can be, in one way or another, expanded to include all persons as it does in Canada. As typically high-end consumers of health care services, people with disabilities are key ... | ['Adolescent', 'Adult', 'Age Factors', 'Canada', 'Chi-Square Distribution', 'Cross-Sectional Studies', 'Developmental Disabilities', 'Disabled Persons', 'Global Health', 'Health Policy', 'Health Services Accessibility', 'Health Status Disparities', 'Health Surveys', 'Humans', 'Logistic Models', 'Male', 'Medically Unins... | 21,122,730 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.107.567.176'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.625.421'], ['M01.150'], ['H02.403.371', 'N01.... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Monosomy of 1p13.3-22.3 in twins. | Twin girls with deletion 1p13.3----22.3 are reported. They are characterised by psychomotor retardation, short stature, narrowing of the external auditory meati and abnormalities of the digits. A high resolution analysis revealed the karyotype to be: 46,XX,-1,-4,-9,-18, +der(1)t(1:9) (p22.3;q13)inv(1)(p13.2:q25) del (1... | ['Adult', 'Chromosome Aberrations', 'Chromosome Disorders', 'Chromosomes, Human, Pair 1', 'Female', 'Gene Rearrangement', 'Humans', 'Karyotyping', 'Monosomy', 'Phenotype', 'Translocation, Genetic', 'Twins'] | 2,036,744 | [['M01.060.116'], ['C23.550.210', 'G05.365.590.175'], ['C16.131.260', 'C16.320.180'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ['G05.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['C23.550.210.050.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The function of the milk-clotting enzymes bovine and camel chymosin studied by a fluorescence resonance energy transfer assay. | Enzymatic coagulation of bovine milk can be divided in 2 steps: an enzymatic step, in which the Phe105-Met106 bond of the milk protein bovine ê-casein is cleaved, and an aggregation step. The aspartic peptidases bovine and camel chymosin (EC 3.4.23.4) are typically used to catalyze the enzymatic step. The most commonly... | ['Animals', 'Camelus', 'Caseins', 'Cattle', 'Chymosin', 'Fluorescence Resonance Energy Transfer', 'Glycosylation', 'Kinetics', 'Milk'] | 25,726,113 | [['B01.050'], ['B01.050.150.900.649.313.500.190.180'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.277.656.074.500.200', 'D08.811.277.656.300.048.200'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['G02.111.158.812', 'G02.607.299', 'G03.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Addressing health inequities through indigenous involvement in health-policy discourses. | Although the health of Indigenous peoples is affected by structural inequities, interventions to address health inequities are often focused locally rather than at a structural level where they could play a transformative role. Addressing structural health inequities by involving Indigenous peoples in health-policy dis... | ['Canada', 'Health Policy', 'Health Services, Indigenous', 'Humans', 'Indians, North American', 'Medically Underserved Area', 'Transcultural Nursing'] | 22,894,009 | [['Z01.107.567.176'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N02.421.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['N03.349.650.340', 'N05.300.450.520'], ['H02.478.676.920']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Rapid differentiation of nucleotide phosphoramidate diastereomers by electrospray ionization tandem mass spectrometry. | RATIONALE: Nucleotide phosphoramidates are prodrugs which effectively deliver the active nucleotide to target tissues. It was shown that the individual phosphoramidate diastereomers have different antiviral activity, although the active nucleotide is the same. Therefore, a fast and simple analytical method is needed to... | ['Amides', 'Chromatography, High Pressure Liquid', 'Nucleotides', 'Phosphoric Acids', 'Prodrugs', 'Spectrometry, Mass, Electrospray Ionization', 'Stereoisomerism', 'Tandem Mass Spectrometry'] | 22,777,791 | [['D02.065'], ['E05.196.181.400.300'], ['D09.408.620', 'D13.695'], ['D01.029.260.700.675', 'D01.695.625.675'], ['D26.675'], ['E05.196.566.600'], ['G02.607.445.682'], ['E05.196.566.880']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human Bitter Taste Receptors Are Activated by Different Classes of Polyphenols. | Polyphenols may contribute directly to plant-based foodstuffs flavor, in particular to astringency and bitterness. In this work, the bitterness of a small library of polyphenols from different classes [procyanidin dimers type B, ellagitannins (punicalagin, castalagin, and vescalagin) and phenolic acid ethyl esters (pro... | ['Biflavonoids', 'Catechin', 'Cell Line', 'Flavoring Agents', 'Humans', 'Hydrolyzable Tannins', 'Polyphenols', 'Proanthocyanidins', 'Receptors, G-Protein-Coupled', 'Taste'] | 30,056,706 | [['D03.383.663.283.266.450.190', 'D03.633.100.150.266.450.190'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['A11.251.210'], ['D26.650.294', 'D27.720.372.300.353', 'D27.720.744.294', 'G07.203.300.514.500.400', 'J02.500.514.500.400'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
DNA repair in the variable platyfish (Xiphophorus variatus) irradiated in vivo with ultraviolet B light. | Dark- and light-dependent DNA repair processes were studied in vivo in the variable platyfish, Xiphophorus variatus. Excision (dark) repair of the (6-4) photoproduct was more efficient than that of the cyclobutane dimer with approximately 70% of the (6-4) photoproducts removed by 24 h post-UVB radiation compared to app... | ['Animals', 'Cyprinodontiformes', 'DNA Repair', 'Pyrimidine Dimers', 'Ultraviolet Rays'] | 8,234,482 | [['B01.050'], ['B01.050.150.900.493.850.280'], ['G02.111.222', 'G05.219'], ['D03.383.742.686.600', 'D13.695.578.424.600', 'D13.695.740.600'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.578.891', 'G16.500.275.063.725.525.600', 'G16.500.750.775.525.600', 'N06.230... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of foot orthotics on running economy: methodological considerations. | OBJECTIVE: The purpose of the study was to collect preliminary data to address methodological considerations that may impact subject-specific reactions to foot orthotics during running.METHODS: Six endurance-trained recreational runners recruited from a chiropractic college campus wore their preferred running shoes and... | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Orthotic Devices', 'Physical Endurance', 'Running', 'Shoes', 'Young Adult'] | 22,632,593 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.858.442.743'], ['G11.427.680', 'I03.450.642.845.054.600'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['J01.637.215.800'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
Reversible cortical atrophy and cognitive decline induced by valproic acid. | An 18-year-old male suffered from familial progressive myoclonic epilepsy from the age of 7 years. In addition to seizures, there was a marked decline in school performance. At the age of 14 years, sodium valproate was started as add-on therapy; 2 weeks later he was hospitalized in a stuporous state. The serum level of... | ['Adolescent', 'Anticonvulsants', 'Atrophy', 'Cerebral Cortex', 'Cognition Disorders', 'Electroencephalography', 'Epilepsies, Myoclonic', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Recovery of Function', 'Severity of Illness Index', 'Valproic Acid'] | 10,726,594 | [['M01.060.057'], ['D27.505.954.427.080'], ['C23.300.070'], ['A08.186.211.200.885.287.500'], ['F03.615.250'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375.130', 'C10.228.140.490.493.063'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['G16.757'], ['E05.318.308.980.438.475.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
C-reactive protein (CRP) but not the related pentraxins serum amyloid P and PTX3 inhibits the proliferation and induces apoptosis of the leukemia cell line Mono Mac 6. | BACKGROUND: Pentraxins are a family of highly conserved secreted proteins that regulate the innate immune system, including monocytes and macrophages. C-reactive protein (CRP) is a plasma protein whose levels can rise to 1000 ìg/ml from the normal <3 ìg/ ml during inflammation.RESULTS: We find that CRP inhibits prolife... | ['Antigens, CD', 'Apoptosis', 'C-Reactive Protein', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Gene Expression Regulation', 'Humans', 'Inhibitory Concentration 50', 'Leukemia, Myeloid, Acute', 'Leukocytes, Mononuclear', 'Phosphatidylinositol 3-Kinase', 'Phosphoinositide... | 29,202,702 | [['D23.050.301.264.035', 'D23.101.100.110'], ['G04.146.954.035'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo testing of an experimental endosseous implant design. | PURPOSE: The purpose of this study was to test a new implant system with apically expanding, double-hinged wing stabilizers in dogs before human testing.METHODS: Twenty-seven HA-coated endosseous implants were placed in five dog mandibles. The implants were placed into function for 12-weeks after a 12-week healing peri... | ['Animals', 'Dental Implants', 'Dental Prosthesis Design', 'Dental Stress Analysis', 'Dogs', 'Durapatite', 'Female', 'Mandible', 'Prosthesis Failure', 'Titanium'] | 8,859,240 | [['B01.050'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.625', 'E06.912.145'], ['E06.308'], ['B01.050.150.900.649.313.750.250.216.200'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['A0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Copy number increase of oncoprotein CIP2A is associated with poor patient survival in human head and neck squamous cell carcinoma. | BACKGROUND: CIP2A, an inhibitor of PP2A tumour suppressor function, is a widely overexpressed biomarker of aggressive disease and poor therapy response in multiple human cancer types.METHODS: CIP2A and DPPA4 copy number alterations and expression were analysed by fluorescence in situ hybridisation (FISH) and immunohist... | ['Autoantigens', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Disease-Free Survival', 'Female', 'Gene Dosage', 'HeLa Cells', 'Head and Neck Neoplasms', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization, Fluorescence', 'Intracellular Signaling Peptides and Proteins', 'Male', 'Membrane Pro... | 26,436,875 | [['D23.050.422'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['G05.380.350'], ['A11.251.210.190.400', ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Oxygen switching of the epitaxial graphene-metal interaction. | Using photoemission spectroscopy techniques, we show that oxygen intercalation is achieved on an extended layer of epitaxial graphene on Ir(111), which results in the "lifting" of the graphene layer and in its decoupling from the metal substrate. The oxygen adsorption below graphene proceeds as on clean Ir(111), giving... | ['Crystallization', 'Graphite', 'Materials Testing', 'Metal Nanoparticles', 'Nanostructures', 'Oxygen', 'Particle Size'] | 23,051,045 | [['E05.196.300', 'G02.171'], ['D01.268.150.300', 'D01.578.300'], ['E05.570'], ['J01.637.512.600.500'], ['J01.637.512'], ['D01.268.185.550', 'D01.362.670'], ['G02.712']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Screening for refractive errors in preschool children with the vision screener. | BACKGROUND: The Vision Screener is a new, commercial version of the Power Refractor, an off-axis, hand-held video refractor to screen for amblyogenic refractive errors. The aim of our study was to determine the reproducibility of the measurements, compare them to cycloplegic refraction, and evaluate the sensitivity and... | ['Age Distribution', 'Child', 'Child, Preschool', 'False Positive Reactions', 'Germany', 'Humans', 'Infant', 'Patient Compliance', 'Prevalence', 'Refraction, Ocular', 'Refractive Errors', 'Reproducibility of Results', 'Retrospective Studies', 'Vision Screening'] | 17,523,041 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['M01.060.406.448'], ['E01.354.506'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['E05.318.308.985.525.750', 'N01.224.935.59... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Anterior Intrapelvic Approaches: Fracture Patterns You May Want to Reconsider. | The anterior intrapelvic approach with a lateral window is gaining popularity for the surgical treatment of anterior fracture patterns of the acetabulum. Certain fracture patterns and characteristics present challenges when using anterior approaches. This article aims to describe some of the fracture patterns that may ... | ['Acetabulum', 'Fracture Fixation, Internal', 'Fractures, Bone', 'Humans', 'Pelvis'] | 30,688,855 | [['A02.835.232.043.825.108'], ['E04.555.300.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.600']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissolution Trapping of Carbon Dioxide in Heterogeneous Aquifers. | The geologic architecture in sedimentary reservoirs affects the behavior of density-driven flow and the dispersion of CO2-rich brine. The spatial organization and connectivity of facies types play an important role. Low-permeability facies may suppress fingering and reduce vertical spreading, but may also increase tran... | ['Carbon Dioxide', 'Groundwater', 'Models, Theoretical', 'Solubility', 'Water Movements'] | 28,598,155 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G01.311.355'], ['E05.599'], ['G02.805'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Insulin reversibility of the isoproterenol resistance of diabetic rat myocardium. | 1. Efficiency of preventive and reversive insulin therapy was compared on rat myocardium following streptozotocin treatment to study the reversibility of diabetic catecholamine resistance. 2. When insulin substitution was initiated immediately after streptozotocin treatment, insulin successfully prevented the developme... | ['Animals', 'Cardiotonic Agents', 'Diabetes Mellitus, Experimental', 'Dose-Response Relationship, Drug', 'Drug Resistance', 'Female', 'Hypoglycemic Agents', 'Insulin', 'Isoproterenol', 'Male', 'Myocardial Contraction', 'Rats', 'Rats, Wistar'] | 8,981,071 | [['B01.050'], ['D27.505.954.411.222', 'D27.720.799.080'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical significance of antibodies to soluble extractable nuclear antigens (anti-ENA). | Clinical and biological manifestations have been studied in 134 patients whose serum had antibodies to soluble extractable nuclear antigens (ENA). 85 of the patients had anti-RNP antibodies, 18 had anti-Sm antibodies, and 31 had antibodies to one or more soluble nuclear antigen. In all groups, the predominant clinical ... | ['Adolescent', 'Adult', 'Aged', 'Antibodies, Antinuclear', 'Antibody Specificity', 'Child', 'Collagen Diseases', 'DNA', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Raynaud Disease'] | 308,354 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['G12.100'], ['M01.060.406'], ['C17.300.200'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['M01.06... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression of Kindlin-1 in human hepatocellular carcinoma and its prognostic significance. | Kindlin-1 is a member of the Kindlin family of focal adhesion proteins and is implicated in cell adhesion, proliferation, polarity, and motility. Although expression of Kindlin-1 has recently been reported in a variety of human cancers, studies on its expression in human hepatocellular carcinoma (HCC) are currently lac... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Carcinoma, Hepatocellular', 'Disease-Free Survival', 'Female', 'Gene Expression Regulation, Neoplastic', 'Hepatectomy', 'Humans', 'Kaplan-Meier Estimate', 'Liver Neoplasms', 'Male', 'Membrane Proteins', 'Middle Aged', 'Neoplasm Proteins', 'Prognosis'] | 25,592,379 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['G05.308.370'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hydrogen peroxide and coffee induce G:C-->T:A transversions in the lacI gene of catalase-defective Escherichia coli. | The mutagenicity of hydrogen peroxide (H2O2) was compared with that of coffee, a complex mixture which generates H2O2. An Escherichia coli strain defective in catalase activity (katG katE double mutant) and carrying a single copy mucAB (pRW144) plasmid was constructed to enhance the mutagenic response to oxidants. The ... | ['Acatalasia', 'Bacterial Proteins', 'Base Sequence', 'Coffee', 'DNA Mutational Analysis', 'Escherichia coli', 'Escherichia coli Proteins', 'Hydrogen Peroxide', 'Lac Operon', 'Lac Repressors', 'Molecular Sequence Data', 'Mutagens', 'Mutation', 'Point Mutation', 'Repressor Proteins'] | 10,474,829 | [['C16.320.565.663.050', 'C18.452.648.663.050'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D20.215.784.249', 'G07.203.100.325', 'J02.200.325'], ['E05.393.760.700.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D01.248.497.158.685.750.424', 'D01.3... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Identification and isolation of Lewis blood group antigens from human saliva using monoclonal antibodies. | Solid-phase radioimmunoassay, polyacrylamide gel electrophoresis and thin-layer chromatography were used to compare, identify, and characterize the Lewis antigens from human salivas, using monoclonal antibodies directed to the Lea and Leb determinants. Sialylated Lea glycolipid was detected in saliva from individuals w... | ['Antibodies, Monoclonal', 'Glycolipids', 'Glycoproteins', 'Humans', 'Lewis Blood Group Antigens', 'Molecular Weight', 'Phenotype', 'Saliva'] | 6,469,267 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D09.400.410', 'D10.390'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D23.050.301.290.544', 'D23.050.705.230.544'], ['G02.494'], ['G05.695'], ['A12.200.666']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Pharmacokinetics and tolerance of roentgen contrast media]. | The improved tolerance of nonionic contrast media compared with conventional contrast media is mainly due to their lower osmolality and reduced allergoid potential. Tolerance advantages that have been definitely proven are, for example, low-pain contrast medium injection and superior systemic tolerance; side effects of... | ['Angiography', 'Contrast Media', 'Drug Hypersensitivity', 'Hemodynamics', 'Humans', 'Kidney', 'Pulmonary Circulation', 'Risk', 'Subtraction Technique', 'Tomography, X-Ray Computed', 'Urography'] | 3,547,606 | [['E01.370.350.700.060', 'E01.370.370.050'], ['D27.505.259.500', 'D27.720.259'], ['C20.543.206', 'C25.100.468'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['G09.330.100.770', 'G09.772.593'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Excitation-contraction coupling in the smooth muscle cells of the rabbit main pulmonary artery. | 1. Increasing the external K concentration depolarizes the smooth muscle cells of the main pulmonary artery, and this depolarization reaches a maximal slope of 58 mV for a tenfold change of [K](o). The threshold depolarization for inducing contraction is at 4 mV and the maximal contraction is reached at a [K](o) of 58 ... | ['Animals', 'Caffeine', 'Calcium', 'Female', 'In Vitro Techniques', 'Male', 'Membrane Potentials', 'Muscle Contraction', 'Muscle, Smooth', 'Norepinephrine', 'Potassium', 'Pulmonary Artery', 'Rabbits'] | 915,834 | [['B01.050'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preliminary surface analysis of etched, bleached, and normal bovine enamel. | X-ray photoelectron spectroscopic (XPS) and secondary ion-mass spectroscopic (SIMS) analyses were performed on unground un-pumiced, unground pumiced, and ground labial enamel surfaces of young bovine incisors exposed to four different treatments: (1) immersion in 35% H2O2 for 60 min; (2) immersion in 37% H3PO4 for 60 s... | ['Acid Etching, Dental', 'Adhesiveness', 'Animals', 'Cattle', 'Dental Bonding', 'Dental Enamel', 'Dental Stress Analysis', 'Electron Probe Microanalysis', 'Hydrogen Peroxide', 'Resins, Synthetic', 'Surface Properties', 'Tensile Strength', 'Tooth Bleaching'] | 2,204,642 | [['E06.931.475.111'], ['G02.860.139'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E06.095'], ['A14.549.167.900.255'], ['E06.308'], ['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Relation of the effect of psychostimulants on learning ability to internal and external factors]. | It has been shown in rat experiments that the action of psychostimulants on the learning ability of rats in a T-shape maze and Dombrovskaya's maze depends to a greater degree on the problem complexity rather than on its type. The learning ability was enhanced in animals which responded to stress by the manifestations o... | ['Amphetamine', 'Animals', 'Antidepressive Agents', 'Caffeine', 'Central Nervous System Stimulants', 'Humans', 'Learning', 'Meclofenoxate', 'Nicotinic Acids', 'Piracetam', 'Rats', 'Stress, Psychological', 'Sydnones'] | 6,140,969 | [['D02.092.471.683.152.110'], ['B01.050'], ['D27.505.954.427.700.122'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D27.505.696.282', 'D27.505.954.427.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['D02.241.081.018.386.682.875', 'D02.241.511.316.495'], ['D03.066.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma. | BACKGROUND:: Surgical excision is the treatment of choice for basal cell carcinoma and micrographic surgery considered the gold standard, however not yet used routinely worldwide available, as in Brazil. Considering this, a previously developed treatment guideline, which the majority of tumors were treated by conventio... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Carcinoma, Basal Cell', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Mohs Surgery', 'Neoplasm Recurrence, Local', 'Practice Guidelines as Topic', 'Reproducibility of Results', 'Risk Assessment', 'Skin Neoplasms', 'Treatment Outcome', 'Tumor Burde... | 28,099,591 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.494.575', 'E0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Prognostic significance of the genetic and the immunohistochemical expression of epithelial-mesenchymal-related markers in colon cancer. | BACKGROUND: Epithelial-mesenchymal transition (EMT) is one of the main events in colorectal cancer (CRC) spread. Snail-1 is a zinc transcription factor that mediates EMT in tumor cells probably by down-regulation of E-cadherin and claudin-1.OBJECTIVES: To detect the expression of epithelial markers (claudin-1 and E-cad... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Cadherins', 'Claudin-1', 'Colorectal Neoplasms', 'Epithelial-Mesenchymal Transition', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prognosis', 'Snail Family Transcription Factors', 'Vimentin', 'Young Adult'] | 28,759,954 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['D12.776.543.940.200.100'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['G04.356.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A comparison of the health status and health care utilization patterns between foreigners and the national population in Spain: new evidence from the Spanish National Health Survey. | The increasing proportion of immigrants in Spanish society is placing pressure on the National Health Care System to accommodate the needs of this population group while keeping costs under control. In the year 2000, a law was approved in Spain according to which all people, regardless of their nationality, are entitle... | ['Emigration and Immigration', 'Health Services', 'Health Status Disparities', 'Health Surveys', 'Humans', 'Models, Economic', 'Prejudice', 'Regression Analysis', 'Risk Assessment', 'Self-Assessment', 'Socioeconomic Factors', 'Spain', 'Statistics as Topic'] | 19,523,727 | [['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['N02.421'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.600', 'E05.599... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Identification and characterization of a salivary-pellicle-binding peptide by phage display. | OBJECTIVE: Dental biofilms are associated with oral diseases, making their control necessary. One way to control them is to prevent initial bacterial adherence to the salivary pellicle and thereby eventually decrease binding of late colonizing potential pathogens. The goal of this study was to generate a salivary-pelli... | ['Amino Acid Sequence', 'Bacterial Adhesion', 'Bacterial Proteins', 'Bacteriophages', 'Biofilms', 'Dental Pellicle', 'Durapatite', 'Humans', 'Saliva', 'Salivary Proteins and Peptides', 'Streptococcus gordonii'] | 24,607,635 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G06.099.050'], ['D12.776.097'], ['B04.123'], ['A20.593', 'G06.120'], ['A14.549.167.900.255.500'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['B01.050.150.900.649.313.988.400.112.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ideal cardiovascular health metrics and its association with 20-year cardiovascular morbidity and mortality in a Chinese population. | BACKGROUND: The American Heart Association (AHA) developed a simplified assessment tool based on seven ideal cardiovascular health (CVH) metrics, but the relationship between the AHA defined ideal CVH metrics and cardiovascular risk in Chinese population has not been well estimated.METHODS: The baseline survey were con... | ['Adult', 'Cardiovascular Diseases', 'China', 'Female', 'Follow-Up Studies', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Prospective Studies', 'Risk Assessment'] | 29,653,994 | [['M01.060.116'], ['C14'], ['Z01.252.474.164'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.500.700', 'E05.318... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Exploration of the Effect and Mechanism of ShenQi Compound in a Spontaneous Diabetic Rat Model. | BACKGROUND: Type 2 Diabetes Mellitus (T2DM) is a world-wide metabolic disease with no cure from drugs and treatment. In China, The Traditional Chinese Medicine (TCM) herbal formulations have been used to treat T2DM for centuries.METHODS: In this study, we proposed a formula called ShenQi Compound (SQC), which has been ... | ['Animals', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Drugs, Chinese Herbal', 'Gene Expression Profiling', 'Male', 'Medicine, Chinese Traditional', 'Microarray Analysis', 'Rats', 'Rats, Wistar', 'Sitagliptin Phosphate'] | 30,799,801 | [['B01.050'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.750.149', 'C19.246.300'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['D20.215.784.500.350', 'D26.335'], ['E05.393.332'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Human urinary bladder carcinoma cell line (T24) in long-term culture: chromosomal studies on a wild population and derived sublines. | Karyotype changes of human urinary bladder carcinoma T24 cell line were studied in the course of 5-year in vitro cultivation. It has been found that the modal number of chromosomes gradually shifted from hypotetraploidy to triploidy during long-term cultivation. The number of endoreduplications was decreasing simultane... | ['Cell Line', 'Chromosome Aberrations', 'Chromosomes', 'Clone Cells', 'Culture Techniques', 'Humans', 'Karyotyping', 'Urinary Bladder Neoplasms'] | 895,941 | [['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['A11.251.353'], ['E05.481.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['C04.588.945.947.960', 'C12.7... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms. | Staphylococcus aureus is a major cause of morbidity and mortality worldwide. S. aureus colonizes 20 to 80% of humans at any one time and causes a variety of illnesses. Strains that are resistant to common antibiotics further complicate management. S. aureus vaccine development has been unsuccessful so far, largely due ... | ['Adaptive Immunity', 'Animals', 'Antibodies, Bacterial', 'Bacteremia', 'Female', 'Gastrointestinal Tract', 'Immunity, Humoral', 'Immunization, Passive', 'Mice', 'Mice, Inbred C57BL', 'Necrosis', 'Skin', 'Soft Tissue Infections', 'Staphylococcal Infections', 'Staphylococcal Vaccines', 'Staphylococcus aureus', 'Th1 Cell... | 30,327,437 | [['G12.450.050'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['A03.556'], ['G12.450.050.420'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of antepartal stress on health status during early motherhood. | A group of high-risk women who were hospitalized for a pregnancy-risk complication, and a group of low-risk women experiencing normal pregnancy were compared for differences in health status and the effects of antepartal stress on their health status from pregnancy through early motherhood. High-risk women reported a s... | ['Adult', 'Female', 'Health Status', 'Humans', 'Models, Psychological', 'Mothers', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Complications', 'Risk Factors', 'Stress, Psychological'] | 2,237,000 | [['M01.060.116'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['G08.686.784.769'], ['C13.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Magnetic Polyurea Nano-Capsules Synthesized via Interfacial Polymerization in Inverse Nano-Emulsion. | Polyurea (PU) nano-capsules have received voluminous interest in various fields due to their biocompatibility, high mechanical properties, and surface functionality. By incorporating magnetic nanoparticle (MNPs) into the polyurea system, the attributes of both PU and MNPs can be combined. In this work, we describe a fa... | ['DEET', 'Drug Compounding', 'Emulsions', 'Isocyanates', 'Magnetite Nanoparticles', 'Nanocapsules', 'Particle Size', 'Polyamines', 'Polymerization', 'Polymers', 'Toluene', 'Trimethylsilyl Compounds'] | 31,340,486 | [['D02.065.277.194', 'D02.241.223.100.100.230', 'D02.455.426.559.389.127.085.230'], ['E05.916.270'], ['D20.280.260', 'D26.255.165.260'], ['D02.500'], ['J01.637.512.600.500.144.500'], ['D26.255.260.575', 'E02.319.300.380.575', 'J01.637.512.600.575'], ['G02.712'], ['D02.092.782'], ['G02.750'], ['D05.750', 'D25.720', 'J01... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Direct Comparison of Amino Acid and Salt Interactions with Double-Stranded and Single-Stranded DNA from Explicit-Solvent Molecular Dynamics Simulations. | Given the ubiquitous nature of protein-DNA interactions, it is important to understand the interaction thermodynamics of individual amino acid side chains for DNA. One way to assess these preferences is to perform molecular dynamics (MD) simulations. Here we report MD simulations of 20 amino acid side chain analogs int... | ['Amino Acids', 'DNA', 'Molecular Dynamics Simulation', 'Salts', 'Solvents', 'Thermodynamics'] | 28,288,277 | [['D12.125'], ['D13.444.308'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D01.786'], ['D27.720.844'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The silk moth Bombyx mori U1 and U2 snRNA variants are differentially expressed. | Five U1 and eight U2 isoforms of the silk moth Bombyx mori exhibiting internal nucleotide differences have been previously identified and characterized in various tissues and developmental stages. In this investigation, it is demonstrated that the levels of some snRNA variants differ in egg and silk gland tissue and ch... | ['Animals', 'Base Sequence', 'Bombyx', 'Chi-Square Distribution', 'DNA', 'DNA, Complementary', 'Databases, Nucleic Acid', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Gene Library', 'Genetic Variation', 'Genome', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'RNA, Small Nuclear',... | 15,894,437 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D13.444.308'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['L01.31... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Task difficulty modulates electrophysiological correlates of perceptual learning. | To investigate the influence of task difficulty on the neural mechanisms of visual perceptual learning, we recorded event-related potentials (ERPs) from human adults while they were trained with either an easy or a difficult orientation discrimination task. The discrimination thresholds of participants trained with the... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Brain Mapping', 'Discrimination, Psychological', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Humans', 'Learning', 'Male', 'Neuropsychological Tests', 'Orientation', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Psychophysics', 'Reaction Time', 'Visu... | 19,969,030 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.593.257'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Controlled aggregates of magnetite nanoparticles for highly sensitive MR contrast agent. | We have prepared a magnetite encapsulated polymer nanocomposite (MEPN) by an emulsification-diffusion technique and found that the encapsulation efficiency could be precisely controlled according to the portion of magnetite and the capping ligand that covers the surface of the magnetite nanoparticles. The field-depende... | ['Contrast Media', 'Crystallization', 'Ferrosoferric Oxide', 'Image Enhancement', 'Macromolecular Substances', 'Magnetic Resonance Imaging', 'Materials Testing', 'Molecular Conformation', 'Nanoparticles', 'Nanotechnology', 'Particle Size', 'Surface Properties'] | 19,908,740 | [['D27.505.259.500', 'D27.720.259'], ['E05.196.300', 'G02.171'], ['D01.490.100.375', 'D01.490.200.350', 'D01.578.285'], ['E01.370.350.600.350', 'L01.224.308.380'], ['D05'], ['E01.370.350.825.500'], ['E05.570'], ['G02.111.570.820'], ['J01.637.512.600'], ['H01.603', 'J01.897.520.600'], ['G02.712'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Evaluating the use of ABBA-BABA statistics to locate introgressed loci. | Several methods have been proposed to test for introgression across genomes. One method tests for a genome-wide excess of shared derived alleles between taxa using Patterson's D statistic, but does not establish which loci show such an excess or whether the excess is due to introgression or ancestral population structu... | ['Algorithms', 'Animals', 'Butterflies', 'Computer Simulation', 'Evolution, Molecular', 'Gene Flow', 'Genome, Insect', 'Models, Statistical'] | 25,246,699 | [['G17.035', 'L01.224.050'], ['B01.050'], ['B01.050.500.131.617.720.500.500.937.200'], ['L01.224.160'], ['G05.045.250', 'G16.075.250'], ['G05.330.159'], ['G05.360.340.357'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A novel class of small repetitive DNA sequences in Enterococcus faecalis. | The structural organization of Enterococcus faecalis repeats (EFAR) is described, palindromic DNA sequences identified in the genome of the Enterococcus faecalis V583 strain by in silico analyses. EFAR are a novel type of miniature insertion sequences, which vary in size from 42 to 650 bp. Length heterogeneity results ... | ['Base Sequence', 'DNA, Bacterial', 'Enterococcus faecalis', 'Genome, Bacterial', 'Models, Genetic', 'Molecular Sequence Data', 'Repetitive Sequences, Nucleic Acid', 'Sequence Analysis, DNA', 'Sequence Homology, Nucleic Acid'] | 17,425,667 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['G05.360.340.358.207'], ['E05.599.395.397'], ['L01.453.245.667'], ['G02.111.570.080.708', 'G05.360.080.708'], ['E05.393.760.700'], ['G02.111.810.550', 'G05.810.550']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of indomethacin on fetal lung liquid formation. | Experiments were performed on seven anesthetized fetal sheep to evaluate involvement of metabolites of the cyclooxygenase system in lung liquid production. Rates of lung liquid production were determined by dye dilution technique using blue dextran. The control rate of formation of lung liquid in these preparations was... | ['Animals', 'Body Water', 'Female', 'Fetus', 'Indomethacin', 'Lung', 'Pregnancy', 'Sheep'] | 6,713,279 | [['B01.050'], ['A12.207.200'], ['A16.378'], ['D03.633.100.473.420'], ['A04.411'], ['G08.686.784.769'], ['B01.050.150.900.649.313.500.380.791']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The VGF-derived peptide TLQP62 produces antidepressant-like effects in mice via the BDNF/TrkB/CREB signaling pathway. | Recent studies demonstrate that the neuropeptide VGF (nonacronymic)-derived peptide is regulated in the hippocampus by antidepressant therapies. Brain-derived neurotrophic factor (BDNF), tropomyosin-related kinase B (TrkB), cAMP response element-binding protein (CREB) signaling, and monoamine transmitter pathways media... | ['Animals', 'Antidepressive Agents', 'Brain-Derived Neurotrophic Factor', 'Cyclic AMP Response Element-Binding Protein', 'Depressive Disorder', 'Hindlimb Suspension', 'Male', 'Mice', 'Mice, Inbred ICR', 'Motor Activity', 'Neuropeptides', 'Peptides', 'Receptor, trkB', 'Signal Transduction', 'Stress, Psychological', 'Swi... | 24,631,486 | [['B01.050'], ['D27.505.954.427.700.122'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['F03.600.300'], ['E05.472.760.370', 'E05.977.400', 'N06.230.150.440.950.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
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