Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Polyamine synthesis in liver and kidney of flounder in response to methylmercury. | The effect of methylmercury administration on polyamine synthesis was studied in the liver and kidney of the winter flounder (Pseudopleuronectes americanus). A single injection of methylmercury resulted in five- and sevenfold elevations of ornithine decarboxylase activity in the liver and kidney within 15 and 45 h, res... | ['Adenosylmethionine Decarboxylase', 'Animals', 'Fishes', 'Kidney', 'Liver', 'Methylmercury Compounds', 'Ornithine Decarboxylase', 'Polyamines', 'Putrescine', 'Spermidine', 'Spermine'] | 961,909 | [['D08.811.520.224.125.050'], ['B01.050'], ['B01.050.150.900.493'], ['A05.810.453'], ['A03.620'], ['D02.691.750.100.738'], ['D08.811.520.224.125.425'], ['D02.092.782'], ['D02.092.211.415.701', 'D02.092.782.258.784'], ['D02.092.211.415.701.801', 'D02.092.782.677'], ['D02.092.211.415.701.801.821', 'D02.092.782.802']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Schizopeptin 791, a new anabeanopeptin-like cyclic peptide from the cyanobacterium Schizothrix sp. | Schizopeptin 791 (1), a new trypsin inhibitor, related in structure to the anabeanopeptins, was isolated from the hydrophilic extract of the cultured terrestrial cyanobacterium Schizothrix sp. Homo- and heteronuclear 2D NMR techniques as well as HRFABMS determined the gross structure of 1. The relative and absolute ste... | ['Amino Acid Sequence', 'Chromatography, High Pressure Liquid', 'Cyanobacteria', 'Israel', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular', 'Peptides, Cyclic', 'Spectrophotometry, Ultraviolet', 'Trypsin Inhibitors'] | 12,193,029 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.181.400.300'], ['B03.280', 'B03.440.475.100'], ['Z01.252.245.500.375'], ['G02.111.570', 'G02.466'], ['E05.196.867.519.550'], ['D04.345.566', 'D12.644.641'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D27.505.519.389.745.800.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Measurement of mental fatigability by task related spectral EEG. A pilot study. | BACKGROUND: Task related EEG spectra are promising markers of mental activity. But the cooperation of the patients necessary for the registration limits its application in the neuro-psychiatry.METHODS: EEG difference spectra on counting (EDSC)--was developed to detect the effect of a short calculation task on the spect... | ['Adult', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Brain', 'Dementia', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Mathematical Computing', 'Mental Fatigue', 'Middle Aged', 'Pilot Projects', 'Stroke'] | 19,248,725 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['C10.228.140.380', 'F03.615.400'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.680'], ['C23.888.369.500', 'F01.145.126.9... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Should maternal alpha-fetoprotein estimation be carried out in centers where ultrasound screening is routine? A sensitivity analysis approach. | We describe a case of small, open spina bifida that was detected on the basis of maternal serum alpha-fetoprotein levels but consistently missed on careful ultrasound examination. This prompted us to reexamine the policy (adopted by an increasing number of departments) of relying exclusively on ultrasound examination f... | ['Adolescent', 'Amniocentesis', 'Female', 'Fetal Diseases', 'Humans', 'Pregnancy', 'Prenatal Diagnosis', 'Sensitivity and Specificity', 'Spina Bifida Occulta', 'Ultrasonography', 'alpha-Fetoproteins'] | 2,453,116 | [['M01.060.057'], ['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E01.370.378.630'], ['E05.318.370.800', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characteristics and comparison of colorectal cancer incidence in Beijing with other regions in the world. | BACKGROUND: Population-based epidemiologic studies about colorectal cancer are lacking in China. This study aims to provide a basis for colorectal cancer screening and prevention, through analysis and comparisons the characteristics of the trends in colorectal cancer incidence in Beijing and selected representative reg... | ['Aged', 'Beijing', 'Colorectal Neoplasms', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged'] | 28,445,947 | [['M01.060.116.100'], ['Z01.252.474.164.225', 'Z01.433.114'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Insecticidal, antifeedant and oviposition deterrent effects of the essential oil and individual compounds from leaves of Chloroxylon swietenia DC. | Essential oil from the leaves of Chloroxylon swietenia DC. was obtained by hydrodistillation and cold extraction, and the chemical composition was determined by gas chromatography and gas chromatography-mass spectrometry. The major identified components were limonene, geijerene, pregeijerene, germacrene D and trans-bet... | ['Animals', 'Feeding Behavior', 'Insecticides', 'Oils, Volatile', 'Oviposition', 'Plant Extracts', 'Plant Leaves', 'Rutaceae', 'Spodoptera'] | 16,847,821 | [['B01.050'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D10.627.675'], ['G08.686.784.480'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['B01.650.940.800.575.912.250.875'], ['B01.050.500.131.617.720.500.500.937.650.700']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contribution of the oocyte nucleus and cytoplasm to the determination of meiotic and developmental competence in mice. | BACKGROUND: Mammals have two types of full-grown oocytes: those with germinal vesicles (GVs) in which the chromatin is condensed and surrounds the nucleolus (surrounded-nucleolus (SN)-type) and those in which the chromatin is less condensed and does not surround the nucleolus (non-surrounded-nucleolus (NSN)-type). Alth... | ['Animals', 'Cell Nucleus', 'Chromatin', 'Cytoplasm', 'Female', 'Meiosis', 'Mice', 'Oocytes', 'Ovarian Follicle'] | 18,367,455 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['A11.284.430.214'], ['G04.144.220.220.687', 'G05.113.220.687'], ['B01.050.150.900.649.313.992.635.505.500'], ['A05.360.490.690.680', 'A11.497.497.600'], ['A05.360.319.114.630... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intrauterine-neonatal torsion of the spermatic cord in an Ethiopian newborn. | The case of a neonate with scrotal swelling noted 6 hours after birth is presented. Scrotal exploration at 12 hours of age revealed a right extravaginal testicular torsion with ischemic necrosis of the testis. Intrauterine and neonatal torsion of the spermatic cord is an uncommon problem accounting for 5 to 6 percent o... | ['Ethiopia', 'Fetal Diseases', 'Humans', 'Infant, Newborn', 'Male', 'Necrosis', 'Orchiectomy', 'Spermatic Cord Torsion'] | 8,404,887 | [['Z01.058.290.120.310'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C23.550.717'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'], ['C12.294.693']] | ['Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The effect of constant threat of terror on Israeli Jewish and Arab adolescents. | The effect on Israeli Jewish and Arab adolescents of living under constant threat of terrorist attacks was assessed in a sample of 346 adolescents. The study probed their direct and indirect exposure to terrorist attacks, avoidance of public centers, sharing feelings with significant others, and stress reaction symptom... | ['Adolescent', 'Affect', 'Arabs', 'Demography', 'Female', 'Humans', 'Israel', 'Jews', 'Male', 'Prevalence', 'Stress Disorders, Post-Traumatic', 'Stress, Psychological', 'Terrorism', 'Time Factors', 'Violence'] | 17,999,214 | [['M01.060.057'], ['F01.470.047'], ['M01.686.754.167'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['M01.686.754.600'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['F03.950.75... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Sialidase, chondroitinase ABC, and combination therapy after spinal cord contusion injury. | Axon regeneration in the central nervous system is severely hampered, limiting functional recovery. This is in part because of endogenous axon regeneration inhibitors that accumulate at the injury site. Therapeutic targeting of these inhibitors and their receptors may facilitate axon outgrowth and enhance recovery. A r... | ['Animals', 'Chondroitin ABC Lyase', 'Disease Models, Animal', 'Enzyme Stability', 'Female', 'Immunohistochemistry', 'Nerve Regeneration', 'Neuraminidase', 'Neuroprotective Agents', 'Rats', 'Rats, Sprague-Dawley', 'Recovery of Function', 'Spinal Cord Injuries'] | 22,934,782 | [['B01.050'], ['D08.811.520.241.700.350.500.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.916.360', 'G02.111.700.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Abdominal tomoradiometry: its possibilities]. | Computer-assisted tomography opens up a new diagnostic chapter in research on abdominal lesions. The display of very faint contrasts, and the possibility of modulating them and of strengthening them by opacifying agents, afford hitherto unknown differentiations. The obtaining of cross-sections is another advantage of t... | ['Abdominal Injuries', 'Adult', 'Aged', 'Alcoholism', 'Cholangitis', 'Cystadenocarcinoma', 'Diagnosis, Differential', 'Humans', 'Lymphoma', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Pancreatic Neoplasms', 'Pancreatitis', 'Tomography, X-Ray Computed'] | 472,693 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The efficacy of EMG-biofeedback training on quadriceps muscle strength in patients after arthroscopic meniscectomy. | AIMS: In 40 patients, we attempted to investigate the efficacy of electromyography-biofeedback (EMG-B) on quadriceps muscle strength after arthroscopic meniscectomy.METHODS: The patients were randomly divided into two groups each consisting of 20 subjects. For the control group, a classical exercise program was given (... | ['Adult', 'Arthroscopy', 'Biofeedback, Psychology', 'Electromyography', 'Humans', 'Knee Injuries', 'Male', 'Menisci, Tibial', 'Muscle Contraction', 'Quadriceps Muscle', 'Range of Motion, Articular', 'Treatment Outcome'] | 16,258,579 | [['M01.060.116'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['A02.165.308.538.500', 'A02.835.583.475.590', 'A10.165.382.350... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Predictors of aggression on the psychiatric inpatient service: self-esteem, narcissism, and theory of mind deficits. | Aggressive behavior committed by inpatients has significant negative effects on patients, clinical staff, the therapeutic milieu, and inpatient community as whole. Past research examining nonpsychiatric patient groups has suggested that elevated self-esteem and narcissism levels as well as self-serving theory of mind (... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Aggression', 'Educational Status', 'Female', 'Hospitalization', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Models, Psychological', 'Narcissism', 'Probability', 'Psychiatric Department, Hospital', 'Residence Characteristics', 'Self Concept', 'Self-Assessment',... | 17,502,810 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.126.125', 'F01.145.813.045'], ['N01.824.196'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['E05.599.695'], ['F02.739.794.582'], ['E05.318.740.600', 'G17.680', 'N... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Chinese medicine clinical trial protocol design and report specifications]. | Clinical trial protocol is the document that illustrates the background of a clinical trial, theoretic basis, objective, design, methods, and organization, as well as statistical calculating, implement, and conditions for completion. Clinical trial protocol is the basic measure for ensuring the validity of scientific r... | ['Clinical Trials as Topic', 'Drugs, Chinese Herbal', 'Humans', 'Medicine, Chinese Traditional', 'Research Design'] | 25,223,170 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['E05.581.500', 'H01.770.644.728']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Streptomyces atriruber sp. nov. and Streptomyces silaceus sp. nov., two novel species of equine origin. | Two actinomycete strains, NRRL B-24165(T) and NRRL B-24166(T), isolated from lesions on equine placentas in Kentucky, USA, were analysed using a polyphasic taxonomic approach. On the basis of phylogenetic analysis of 16S rRNA gene sequences, morphological observations and the presence of ll-diaminopimelic acid as the d... | ['Animals', 'DNA, Bacterial', 'DNA, Ribosomal', 'Female', 'Horses', 'Molecular Sequence Data', 'Phylogeny', 'Placenta', 'Pregnancy', 'RNA, Ribosomal, 16S', 'Streptomyces'] | 19,628,594 | [['B01.050'], ['D13.444.308.212'], ['D13.444.308.475'], ['B01.050.150.900.649.313.984.235.472'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['A16.710'], ['G08.686.784.769'], ['D13.444.735.686.670'], ['B03.300.390.400.810.768', 'B03.510.024.997.775', 'B03.510.415.400.810.768', 'B03.510.460.410.810.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intermolecular relations between the glucocorticoid receptor, ZAP-70 kinase, and Hsp-90. | The glucocorticoid receptor (GR) participates in both genomic and non-genomic glucocorticoid hormone (GC) actions by interacting with other cytoplasmic signalling proteins. Previously, we have shown that high dose Dexamethasone (DX) treatment of Jurkat cells causes tyrosine phosphorylation of ZAP-70 within 5 min in a G... | ['HSP90 Heat-Shock Proteins', 'HeLa Cells', 'Humans', 'Jurkat Cells', 'Protein Binding', 'Receptors, Glucocorticoid', 'Subcellular Fractions', 'ZAP-70 Protein-Tyrosine Kinase'] | 17,222,799 | [['D12.776.580.216.380'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567.569.440'], ['G02.111.679', 'G03.808'], ['D12.776.826.750.430'], ['A11.284.835'], ['D08.811.913.696.620.682.725.900... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of the tolerability and efficacy of sodium polystyrene sulfonate for long-term management of hyperkalemia in patients with chronic kidney disease. | PURPOSE: Sodium polystyrene sulfonate (SPS) is a cation-exchanging resin that has been widely used for several decades as first-line therapy of mild chronic hyperkalemia in patients with chronic kidney disease (CKD). However, evidence to prove the long-term tolerability and efficacy of SPS for the treatment of this con... | ['Aged', 'Aged, 80 and over', 'Calcium', 'Cation Exchange Resins', 'Female', 'Follow-Up Studies', 'Humans', 'Hyperkalemia', 'Male', 'Middle Aged', 'Polystyrenes', 'Potassium', 'Recurrence', 'Renal Insufficiency, Chronic', 'Retrospective Studies', 'Sodium', 'Time Factors'] | 29,027,620 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.720.470.420.275'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.396'], ['M01.060.116.630'], ['D02.455.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
NagR Differentially Regulates the Expression of the glmS and nagAB Genes Required for Amino Sugar Metabolism by Streptococcus mutans. | UNLABELLED: The ability of bacteria to metabolize glucosamine (GlcN) and N-acetyl-d-glucosamine (GlcNAc) is considered important for persistent colonization of the oral cavity. In the dental caries pathogen Streptococcus mutans, the NagR protein regulates the expression of glmS, which encodes a GlcN-6-P synthetase, and... | ['Amino Acid Sequence', 'Amino Sugars', 'Bacterial Proteins', 'Base Sequence', 'Gene Expression Regulation, Bacterial', 'Molecular Sequence Data', 'Streptococcus mutans'] | 26,324,448 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D09.067'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.300'], ['L01.453.245.667'], ['B03.353.750.737.872.875.520', 'B03.510.400.800.872.875.520', 'B03.510.550.737.872.875.520']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Icariin Acts as a Potential Agent for Preventing Cardiac Ischemia/Reperfusion Injury. | Myocardial infarction is a leading cause of mortality and morbidity worldwide. Although essential for successful recovery, myocardium reperfusion is associated with reperfusion injury. Icariin, a major flavonoid of Epimedium koreanum Nakai, has been proven to exert efficacy for improving cardiovascular function. We inv... | ['Animals', 'Apoptosis', 'Cardiotonic Agents', 'Drugs, Chinese Herbal', 'Flavonoids', 'Male', 'Myocardial Reperfusion Injury', 'Myocytes, Cardiac', 'Nitric Oxide Synthase Type III', 'Phosphatidylinositol 3-Kinases', 'Phosphoinositide-3 Kinase Inhibitors', 'Protein Kinase Inhibitors', 'Proto-Oncogene Proteins c-akt', 'R... | 25,663,532 | [['B01.050'], ['G04.146.954.035'], ['D27.505.954.411.222', 'D27.720.799.080'], ['D20.215.784.500.350', 'D26.335'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['C14.280.238.615', 'C14.280.647.625', 'C14.907.585.625', 'C14.907.725.600', 'C23.550.767.877.500'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three-centre study on urinary hydroxyproline excretion in cancer of the breast. | A study instigated by the British Breast Group and involving 3 centres (Edinburgh, Glasgow and Liverpool) was carried out to compare 3 methods for the estimation of urinary hydroxyproline. No significant difference between the first and the second 24 h urine collection was found for each measure of urinary hydroxyproli... | ['Adult', 'Aged', 'Bone Neoplasms', 'Breast Neoplasms', 'Female', 'Humans', 'Hydroxyproline', 'Methods', 'Middle Aged', 'Neoplasm Metastasis', 'Radiography'] | 678,421 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.125.072.401.623.478'], ['E05.581'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Testosterone and luteinizing hormone responses to naloxone help predict sexual performance in rams. | The first objective of this study was to determine whether LH and testosterone respond differently to a naloxone injection in relation to varying sexual performance in rams. If differences occurred, the second objective was to determine whether differences would predict variation in sexual performance. From a group of ... | ['Animals', 'Breeding', 'Female', 'Libido', 'Luteinizing Hormone', 'Male', 'Naloxone', 'Narcotic Antagonists', 'Predictive Value of Tests', 'Sexual Behavior, Animal', 'Testosterone'] | 15,542,486 | [['B01.050'], ['E05.820.150', 'G05.090'], ['F02.739.794.511'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04.615.723.795.706'], ['D27.505.696.543', 'D27.505.696.663.850.512', 'D27.505.954.427.550'], ['E05... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structure-activity correlation in transfection promoted by pyridinium cationic lipids. | The efficiency of the transfection of a plasmid DNA encoding a galactosidase promoted by a series of pyridinium lipids in mixtures with other cationic lipids and neutral lipids was assessed in CHO-K1 cells. We identify key molecular parameters of the lipids in the mixture - clog P, lipid length, partial molar volume - ... | ['Animals', 'CHO Cells', 'Cations', 'Cell Survival', 'Cricetulus', 'DNA', 'Galactosidases', 'Lipids', 'Plasmids', 'Pyridinium Compounds', 'Transfection'] | 26,891,970 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['D01.248.497.300'], ['G04.346'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D13.444.308'], ['D08.811.277.450.410'], ['D10'], ['G05.360.600'], ['D03.383.725.762'], ['E05.393.350.810', 'G05.728.860']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cordylobia anthropophaga as a cause of cutaneous myiasis in a dog in Germany]. | This paper reports on a case of cutaneous myiasis due to Cordylobia anthropophaga in a dog imported from Cameroon to Germany. An account is given of the biology and ecology of this skin maggot fly as well as the clinics, diagnosis and treatment of the cutaneous myiasis are reviewed. | ['Animals', 'Diptera', 'Dog Diseases', 'Dogs', 'Germany', 'Larva', 'Male', 'Myiasis', 'Skin Diseases'] | 8,999,598 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['Z01.542.315'], ['B05.500.500', 'G07.345.500.550.500.500'], ['C01.610.858.211.503'], ['C17.800']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Discovery of Novel Schizocommunin Derivatives as Telomeric G-Quadruplex Ligands That Trigger Telomere Dysfunction and the Deoxyribonucleic Acid (DNA) Damage Response. | Telomeric G-quadruplex targeting and telomere maintenance interference are emerging as attractive strategies for anticancer therapies. Here, a novel molecular scaffold is explored for telomeric G-quadruplex targeting. A series of novel schizocommunin derivatives was designed and synthesized as potential telomeric G-qua... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Cell Line, Tumor', 'Cell Proliferation', 'DNA', 'DNA Damage', 'Drug Discovery', 'Female', 'G-Quadruplexes', 'G2 Phase Cell Cycle Checkpoints', 'Humans', 'Indoles', 'Ligands', 'Mice, Inbred BALB C', 'Telomerase', 'Telomere', 'Telomere Shortening', 'Telomere-Binding Prot... | 29,618,208 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D13.444.308'], ['G05.200'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['G02.111.570.820.486.550', 'G05.360.580.550'], ['G04.144.109.500', 'G04.144.500.340.500'], ['B01.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Age, but not pineal status, modulates circadian periodicity of golden hamsters. | The pineal gland and its hormone, melatonin, have been implicated in the regulation of rat circadian rhythmicity. The present study was designed to evaluate whether the pineal has a similar role in the hamster, and to clarify whether the marked rhythm responses to constant light (LL) previously seen in serotonin-deplet... | ['Age Factors', 'Animals', 'Circadian Rhythm', 'Cricetinae', 'Male', 'Mesocricetus', 'Motor Activity', 'Photoperiod', 'Pineal Gland'] | 8,280,908 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['G07.180.562.190'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['F01.145.632', 'G11.427.410.698'], ['G01.910.675'], ['A06.300.635', 'A06.688.733', 'A08.186.211.180.200.680', 'A08.186.211.200.317.200.620', 'A08.713.... | ['Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cell aggregation by scaffolded receptor clusters. | The aggregation of cells by lectins or antibodies is important for biotechnological and therapeutic applications. One strategy to augment the avidity and aggregating properties of these mediators is to maximize the number of their ligand binding sites. The valency of lectins and antibodies, however, is limited by their... | ['Cell Aggregation', 'Concanavalin A', 'Energy Transfer', 'Humans', 'Jurkat Cells', 'Macromolecular Substances', 'Models, Molecular', 'Protein Folding', 'Receptors, Concanavalin A'] | 11,880,031 | [['G04.198.251'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567.569.440'], ['D05'], ['E05.599.595'], ['G01.154.651', 'G02.111.688'], ['D12.776.543.750.705.880... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection. | BACKGROUND: Cell-surface mucins are expressed in apical epithelial cells of the respiratory tract, and contribute a crucial part of the innate immune system. Despite anti-inflammatory or antiviral functions being revealed for certain cell-surface mucins such as MUC1, the roles of other mucins are still poorly understoo... | ['Animals', 'Cells, Cultured', 'Chemokines', 'Cytokines', 'Dogs', 'Epithelial Cells', 'ErbB Receptors', 'Humans', 'Influenza A Virus, H3N2 Subtype', 'Influenza, Human', 'Madin Darby Canine Kidney Cells', 'Mucins', 'Nasal Cavity', 'RNA Interference', 'RNA, Small Interfering', 'Recombinant Proteins', 'Up-Regulation', 'Vi... | 31,307,416 | [['B01.050'], ['A11.251'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.750.250.216.200'], ['A11.436'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta. | In intact porcine aorta, endothelium-derived nitric oxide released on thrombin stimulation inhibits the concomitant production of endothelin. Experiments were designed to examine the effect of hirudin (which inactivates thrombin) and the nitrovasodilators nitroglycerin and 3-morpholinosydnonimine on the spontaneous and... | ['Animals', 'Aorta', 'Calcimycin', 'Endothelins', 'Hirudins', 'In Vitro Techniques', 'Methylene Blue', 'Nitrates', 'Nitroglycerin', 'Swine', 'Thrombin'] | 1,903,680 | [['B01.050'], ['A07.015.114.056'], ['D03.633.100.221.173'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['D12.644.861.060.875', 'D12.776.872.060.875'], ['E05.481'], ['D02.886.369.517', 'D03.633.300.783.517'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D02.640.636'], ['B01.050.150.900.649.313.50... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Descriptive epidemiology of vulvar and vaginal cancers in Vaud, Switzerland, 1974-1994. | BACKGROUND: To analyse trends in incidence, survival and risk of second neoplasms following vaginal and vulvar cancers using data collected by the Swiss Cancer Registry of Vaud over the 21-year period 1974-1994.MATERIALS AND METHODS: Subjects were 257 vulvo-vaginal cancers. Of these, 69 were vaginal, 153 vulvar cancers... | ['Adult', 'Aged', 'Female', 'Humans', 'Incidence', 'Middle Aged', 'Registries', 'Risk Factors', 'Survival Analysis', 'Switzerland', 'Vaginal Neoplasms', 'Vulvar Neoplasms'] | 9,862,054 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['E05.3... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Long-term outcome, survival analysis, and risk stratification of dynamic cardiomyoplasty. | METHODS: To analyze the long-term outcome of dynamic cardiomyoplasty, we retrospectively studied 127 consecutive patients who underwent this procedure in Paris, France (n = 76), S?o Paulo, Brazil (n = 37), and Portland, Oregon (n = 14). Preoperative data were collected for patients operated on between January 1985 and ... | ['Cardiomyoplasty', 'Exercise Test', 'Female', 'Heart Failure', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Patient Selection', 'Predictive Value of Tests', 'Proportional Hazards Models', 'Retrospective Studies', 'Risk', 'Risk Factors', 'Survival Analysis', 'Treatment Outcome'] | 8,975,856 | [['E04.100.376.125', 'E04.928.220.220'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E05.581.500.653', 'N04.590.731'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Full text multilingual automatic morphosemantems for stand-alone or Internet based applications. | The authors present an automatic tool able to provide real-time morphosemantic decomposition of natural language sentences in French, German and English. This tool demonstrates the feasibility of Natural Language Processing on standard PC computers and the technology involved has been successfully implemented in daily ... | ['Classification', 'Internet', 'Multilingualism', 'Natural Language Processing', 'Semantics'] | 10,384,438 | [['L01.100', 'L01.453.245.275'], ['L01.224.230.110.500'], ['L01.559.423.452'], ['L01.224.050.375.580'], ['L01.559.598.745']] | ['Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Are infertility treatments a potential risk factor for cancer development? Perspective of 30 years of follow-up. | The aim of the present study was to evaluate the possible risk for cancer development in infertile women with over 30 years of follow-up. Cancer development was assessed through linkage with the National Cancer Registry updated to 31 December 2005 in a cohort of 2431 women who were treated for infertility at the Sheba ... | ['Adult', 'Breast Neoplasms', 'Cohort Studies', 'Endometrial Neoplasms', 'Female', 'Fertility Agents, Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infertility, Female', 'Israel', 'Medical Records', 'Ovarian Neoplasms', 'Ovulation Induction', 'Registries', 'Reproductive Techniques, Assisted', 'Risk Factors'] | 22,475,084 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['D27.505.696.875.552.344', 'D27.505.954.705.552.344'], ['E05.318.372.500.750.249', 'N05.715.360.330.500... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Celiac disease in India: are they true cases of celiac disease? | BACKGROUND: In a developing country, many conditions other then celiac disease (CD) can give rise to villous atrophy. We therefore assessed the role of immunoglobulin A (IgA)-antigliadin antibody (AGA) in addition to the ESPGHAN criteria in the diagnosis of CD in 104 Indian children.METHODS: Consecutive children with s... | ['Autoantibodies', 'Biomarkers', 'Case-Control Studies', 'Celiac Disease', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Failure to Thrive', 'False Positive Reactions', 'Female', 'Gliadin', 'Glutens', 'Humans', 'Immunoglobulin A', 'India', 'Longitudinal Studies', 'Male', 'Prospective Studies', 'Reference Val... | 12,394,375 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.469.637.250', 'C18.452.603.250'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['C23.888.338'], ['E01.354.506'], ['D... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prevalence of subjective voice impairment in rheumatoid arthritis. | Rheumatoid arthritis (RA) might lead to voice impairment through several mechanisms but its prevalence has been little investigated. RA patients attending a rheumatology outpatient clinic had joint assessments and completed the Voice Handicap Index-10 (VHI-10). A comparator group consisted of patients attending the dep... | ['Aged', 'Arthritis, Rheumatoid', 'Case-Control Studies', 'Disability Evaluation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Severity of Illness Index', 'United Kingdom', 'Voice Disorders'] | 18,716,729 | [['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Precurarization--a hazard to the patient? | Four case histories are presented illustrating the unpleasant and serious reactions that may follow precurarization with small doses of non-depolarizing muscle relaxants. The importance of preoperative information, the necessity of relating the dose of the precurarizing drug to the weight of the patient and the possibi... | ['Adult', 'Anxiety', 'Body Weight', 'Fear', 'Female', 'Humans', 'Male', 'Neuromuscular Blocking Agents', 'Pancuronium', 'Paralysis', 'Preanesthetic Medication', 'Sensation', 'Vecuronium Bromide'] | 6,143,465 | [['M01.060.116'], ['F01.470.132'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.663.700.710'], ['D04.210.500.054.040.685'], ['C10.597.622', 'C23.888.592.636'], ['E03.80... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Blood transfusion during pregnancy, birth, and the postnatal period. | OBJECTIVES: To identify risk factors for transfusion and trends in transfusion rates across pregnancy and the postnatal period.METHODS: Linked hospital and birth data on all births in hospitals in New South Wales, Australia, between 2001 and 2010 were used to identify blood transfusions for women during pregnancy, at b... | ['Adult', 'Blood Transfusion', 'Delivery, Obstetric', 'Female', 'Humans', 'Postpartum Period', 'Pregnancy', 'Retrospective Studies', 'Risk Factors', 'Young Adult'] | 24,463,672 | [['M01.060.116'], ['E02.095.135'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.702'], ['G08.686.784.769'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bauerenol, a triterpenoid from Indian Suregada angustifolia: Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells. | The triterpenoid, bauerenol, from Suregada angustifolia (Baill. ex Muell.-Arg.) Airy Shaw (Euphorbiaceae) was screened for anti-cancer property using hepatocellular carcinoma cell line, HepG2. Bauerenol exhibited growth inhibitory and apoptosis inducing potential against HepG2 cancer cells. 3-(4,5-dimethylthiazol-2-yl)... | ['Apoptosis', 'Carcinoma, Hepatocellular', 'Cyclin D1', 'Gene Expression Regulation, Neoplastic', 'Hep G2 Cells', 'Humans', 'Liver Neoplasms', 'Plant Extracts', 'Reactive Oxygen Species', 'Suregada', 'Triterpenes', 'bcl-2-Associated X Protein', 'p38 Mitogen-Activated Protein Kinases'] | 28,443,465 | [['G04.146.954.035'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['G05.308.370'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis. | Centriolar satellites are small, granular structures that cluster around centrosomes, but whose biological function and regulation are poorly understood. We show that centriolar satellites undergo striking reorganization in response to cellular stresses such as UV radiation, heat shock, and transcription blocks, invoki... | ['Antigens, Neoplasm', 'Autoantigens', 'Blotting, Western', 'Cell Cycle Proteins', 'Centrioles', 'Centrosome', 'Cilia', 'Cytoskeletal Proteins', 'Fluorescent Antibody Technique', 'Humans', 'Immunoenzyme Techniques', 'Microtubule Proteins', 'Mitogen-Activated Protein Kinase 14', 'Neoplasm Proteins', 'Phosphorylation', '... | 24,121,310 | [['D23.050.285'], ['D23.050.422'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.167'], ['A11.284.430.214.190.750.585.160.130', 'A11.284.430.214.190.750.820.500.500.130'], ['A11.284.430.214.190.750.585.160', 'A11.284.430.214.190.750.820.500.500'], ['A11.2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neutrophil elastase enhances IL-12p40 production by lipopolysaccharide-stimulated macrophages via transactivation of the PAR-2/EGFR/TLR4 signaling pathway. | Proteinase-activated receptor 2 (PAR-2) and toll-like receptor 4 (TLR4) are involved in innate immune responses and signaling cross-talk between these receptor molecules has the potential to augment an ongoing inflammatory response. The aim of this study was to evaluate the possible cooperative influence of PAR-2 and T... | ['Cells, Cultured', 'Dual Oxidases', 'ErbB Receptors', 'Humans', 'Interleukin-12 Subunit p40', 'Leukocyte Elastase', 'Lipopolysaccharides', 'Macrophages', 'Receptor Cross-Talk', 'Receptor, PAR-2', 'Signal Transduction', 'Toll-Like Receptor 4', 'Transcriptional Activation'] | 27,282,560 | [['A11.251'], ['D08.811.682.608.575.500', 'D12.776.331.894.500', 'D12.776.543.653.500'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.512.500', 'D12.644.276.374.465.759.249', 'D12.776.467.374.465... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A highly selective ratiometric fluorescent probe based on naphthalimide for detection and imaging of CYP1A1 in living cells and zebrafish. | Real-time monitoring of the cytochrome P450 1A1 (CYP1A1) activity in complex biological systems via a practical tool is highly sought after because of its significant role in the metabolism and bioactivation of various xenobiotics. Herein, according to slight differences in the 3D structure and substrate preference bet... | ['Animals', 'Cell Line, Tumor', 'Cytochrome P-450 CYP1A1', 'Fluorescent Dyes', 'Humans', 'Limit of Detection', 'Microscopy, Confocal', 'Microscopy, Fluorescence', 'Microsomes, Liver', 'Naphthalimides', 'Protein Isoforms', 'Reproducibility of Results', 'Solubility', 'Water', 'Zebrafish', 'Zebrafish Proteins'] | 31,670,325 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.244.453.005.332', 'D08.244.453.100.500', 'D08.811.682.690.708.170.010.277', 'D08.811.682.690.708.170.020.500', 'D12.776.422.220.453.010.332', 'D12.776.422.220.453.100.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases. | The course of hepatitis C virus (HCV) infection carriers with normal/near-normal aminotransferases (NALT) is usually mild; however, in a few, fibrosis progression occurs. We aimed to verify whether monitoring by liver biopsy might be replaced by noninvasive methods and to identify factors associated with fibrosis progr... | ['Adult', 'Aged', 'Alanine Transaminase', 'Algorithms', 'Biomarkers', 'Biopsy', 'Carrier State', 'Disease Progression', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Sensitivity and Specificity', 'Severity of Illness Index', 'Ultrasonography'] | 16,121,354 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.913.477.700.100'], ['G17.035', 'L01.224.050'], ['D23.101'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['N06.850.520.169'], ['C23.550.291.656'], ['C01.221.250.750.120', 'C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Restoration of beta1A integrins is required for lysophosphatidic acid-induced migration of beta1-null mouse fibroblastic cells. | Cells lacking the beta1 integrin subunit or expressing beta1A with certain cytoplasmic mutations have poor directed cell migration to platelet-derived growth factor or epidermal growth factor, ligands of receptor tyrosine kinases (Sakai, T., Zhang, Q., F?ssler, R., and Mosher, D. F. (1998) J. Cell Biol. 141, 527-538). ... | ['Animals', 'Cell Movement', 'Epidermal Growth Factor', 'Fibroblasts', 'Fibronectins', 'Gelatin', 'Gene Expression Regulation', 'Integrin beta1', 'Laminin', 'Lysophospholipids', 'Mice', 'Platelet-Derived Growth Factor', 'Receptor Protein-Tyrosine Kinases', 'Vitronectin'] | 9,677,354 | [['B01.050'], ['G04.198', 'G07.568.500.180'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['A11.329.228'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D12.776.860.476'], ['G05.308'], ['D12.776.543.750.705.408.200.500'], ['D12.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developmental changes in the balance of disparity, blur, and looming/proximity cues to drive ocular alignment and focus. | Accurate coordination of accommodation and convergence is necessary to view near objects and develop fine motor coordination. We used a remote haploscopic videorefraction paradigm to measure longitudinal changes in simultaneous ocular accommodation and vergence to targets at different depths, and to all combinations of... | ['Adolescent', 'Adult', 'Age Factors', 'Child', 'Child Development', 'Child, Preschool', 'Convergence, Ocular', 'Cues', 'Female', 'Humans', 'Infant', 'Longitudinal Studies', 'Male', 'Photic Stimulation', 'Vision Disparity', 'Vision, Binocular', 'Visual Acuity', 'Young Adult'] | 24,344,547 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['G14.350.217'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Age and duration of disease as factors affecting clinical findings and sacroiliitis in brucellosis. | OBJECTIVE: Brucellosis may be seen in any age group, but it still involves young and middle aged adults more frequently. Our aim was to investigate the relationship between age and the duration of disease on clinical findings of brucellosis in adults in this study.PATIENTS AND METHOD: One hundred and sixty-three patien... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Animals', 'Arthritis, Infectious', 'Brucella', 'Brucellosis', 'Female', 'Humans', 'Joint Diseases', 'Male', 'Middle Aged', 'Retrospective Studies', 'Sacroiliac Joint', 'Turkey'] | 17,906,836 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['C01.100', 'C05.550.114.099'], ['B03.440.400.425.215.500', 'B03.660.050.070.100'], ['C01.150.252.400.167'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['M01.060.116.6... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Glycosylation of immunodominant linear epitopes in the carboxy-terminal region of the caprine arthritis-encephalitis virus surface envelope enhances vaccine-induced type-specific and cross-reactive neutralizing antibody responses. | This study evaluated type-specific and cross-reactive neutralizing antibodies induced by immunization with modified surface glycoproteins (SU) of the 63 isolate of caprine arthritis-encephalitis lentivirus (CAEV-63). Epitope mapping of sera from CAEV-infected goats localized immunodominant linear epitopes in the carbox... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Viral', 'Antibody Specificity', 'Arthritis-Encephalitis Virus, Caprine', 'Blotting, Western', 'Cross Reactions', 'Glycosylation', 'Goats', 'Immunodominant Epitopes', 'Membrane Glycoproteins', 'Molecular Sequence Data', 'Neutralization Tests', 'Viral Envelope Proteins', 'V... | 15,308,714 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G12.100'], ['B04.820.650.589.600.070'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G12.122.281'], ['G02.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Long-lifetime Ru(II) complexes as labeling reagents for sulfhydryl groups. | We report the synthesis and spectral properties of two long-lifetime highly luminescent Ru(II) complexes containing either a sulfhydryl reactive iodoacetamido group or a less reactive choloroacetamido group, [Ru(bpy)2(5-iodoacetamido-1,10-phenanthroline)] (PF6)2 and [Ru(bpy)2(5-chloroacetamido-1,10-phenanthroline)](PF6... | ['Cysteine', 'Humans', 'Luminescent Measurements', 'Organometallic Compounds', 'Proteins', 'Ruthenium', 'Spectrophotometry', 'Sulfhydryl Compounds'] | 9,451,499 | [['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.516'], ['D02.691'], ['D12.776'], ['D01.268.556.805', 'D01.268.956.812', 'D01.552.544.805'], ['E05.196.712.726', 'E05.196.867.826'], ['D02.886.489']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of glucagon on myoinositol levels in the blood serum and its excretion with urine. | The investigations were carried out with a group of ten healthy men aged 20--26 years who were injected intravenously with glucagon in a single dose of 50 microgram per kg of body weight. Glucagon had no effect on myoinositol levels in the blood serum. It caused however, a significant decrease in the myoinositol discha... | ['Adult', 'Blood Glucose', 'Glucagon', 'Humans', 'Inositol', 'Kidney', 'Male'] | 747,110 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.800.519', 'D09.853.519'], ['A05.810.453']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Heparin inhibits the inflammation and proliferation of human rheumatoid arthritis fibroblast‑like synoviocytes through the NF‑êB pathway. | Fibroblast-like synoviocytes (FLSs) of rheumatoid arthritis (RA) lead to cartilage destruction, and the activation of NF‑êB is important in the proliferation of FLSs. Heparin is a glycosaminoglycan, which is widely used as an anticoagulant. In the present study, the effect of heparin on the tumor necrosis factor (TNF)‑... | ['Anti-Inflammatory Agents', 'Anticoagulants', 'Arthritis, Rheumatoid', 'Cell Proliferation', 'Cells, Cultured', 'Fibroblasts', 'Heparin', 'Humans', 'Interleukin-6', 'Interleukin-8', 'NF-kappa B', 'Synoviocytes', 'Tumor Necrosis Factor-alpha'] | 27,599,556 | [['D27.505.954.158'], ['D27.505.954.502.119'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['A11.329.228'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Firing rates of motor units in human vastus lateralis muscle during fatiguing isometric contractions. | We investigated the firing rate of motor units in the vastus lateralis muscle in five healthy young men (mean = 21.4 yr, SD = 0.9) during a sequence of isometric constant-torque contractions repeated to exhaustion. The contractions were sustained at 20% of the maximal voluntary level, measured at the beginning of the t... | ['Action Potentials', 'Adult', 'Electromyography', 'Humans', 'Isometric Contraction', 'Knee Joint', 'Male', 'Motor Neurons', 'Muscle Fatigue', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Physical Endurance', 'Physical Exertion', 'Stress, Mechanical'] | 16,036,904 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A02.835.583.475'], ['A08.675.655.500', 'A11.671.655.500'], ['G11.427.550'], ['A10.690.552.500.500', 'A11.620.249'], ['A02.633.567', 'A1... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Top-down, Bottom-up and Sideways: The Multilayered Complexities of Multi-level Actors Shaping Forest Governance and REDD+ Arrangements in Madre de Dios, Peru. | This study examines the role multilevel governance plays in the adoption of sustainable landscape management initiatives in emerging arrangements aimed at reducing emissions from deforestation and forest degradation (REDD+). It sheds light on the challenges these multiple layers of actors and interests encounter around... | ['Conservation of Natural Resources', 'Forests', 'Government Regulation', 'Humans', 'Mining', 'Peru', 'Politics'] | 29,299,626 | [['J01.256', 'N06.230.080'], ['G16.500.275.157.437', 'N06.230.124.343'], ['I01.880.604.394', 'N03.706.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576.655.875.500'], ['Z01.107.757.702'], ['I01.738']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
[Characteristics and sources of elements of atmospheric particles before and in heating period in Beijing]. | In order to study the characteristics and sources of atmospheric particles before and in heating period, samples of atmospheric particles were collected in November of 2006. Concentrations of elements in particles were determined with ICP-MS. The results shows that concentrations of As, Se, Mo, Cd in heating period are... | ['Aerosols', 'Air Pollutants', 'Atmosphere', 'China', 'Coal', 'Environmental Monitoring', 'Factor Analysis, Statistical', 'Humans', 'Metals', 'Particle Size'] | 19,186,840 | [['D20.280.055', 'D26.255.165.055'], ['D27.888.284.101'], ['G16.500.275.063', 'N06.230.300.100'], ['Z01.252.474.164'], ['D20.345.108', 'N06.230.132.258.108'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Inconsistent journalism: the coverage of chronic diseases in the Mexican press. | The mass media are recognized by many social scientists as important sources of medical information for lay people and as a positive influence on those working in the health care professions. However, there is a lack of study about print and mass media reporting on major health problems in developing countries such as ... | ['Bibliometrics', 'Chronic Disease', 'Humans', 'Information Services', 'Journalism, Medical', 'Mass Media', 'Mexico', 'Quality Control', 'Retrospective Studies'] | 11,550,591 | [['L01.178.682.099.325', 'L01.453.183.291'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453'], ['L01.737.498.550'], ['L01.178.590'], ['Z01.107.567.589'], ['J01.897.608'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825',... | ['Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Mutations in the perforin gene in children with hemophagocytic lymphohistiocytosis. | BACKGROUND: Recent studies have reported germline mutations in the perforin gene (PRF1) in some types of hemophagocytic lymphohistiocytosis (HLH). However, the prevalence of PRF1 mutations in HLH in Chinese pediatric patients has not been extensively studied. The aim of this study was to investigate the prevalence of m... | ['Adolescent', 'Amino Acid Sequence', 'Child', 'Child, Preschool', 'Epstein-Barr Virus Infections', 'Female', 'Humans', 'Infant', 'Lymphohistiocytosis, Hemophagocytic', 'Male', 'Molecular Sequence Data', 'Mutation', 'Perforin', 'Polymerase Chain Reaction', 'Pore Forming Cytotoxic Proteins'] | 20,092,789 | [['M01.060.057'], ['G02.111.570.060', 'L01.453.245.667.060'], ['M01.060.406'], ['M01.060.406.448'], ['C01.925.256.466.313', 'C01.925.928.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C15.604.250.410.575'], ['L01.453.245.667'], ['G05.365.590'], ['D12.776.543.695.875'], ['E05.393.620.500'], [... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species. | BACKGROUND: Resident macrophages regulate homeostatic and disease processes in multiple tissues, including the kidney. Despite having well defined markers to identify these cells in mice, technical limitations have prevented identification of a similar cell type across species. The inability to identify resident macrop... | ['Analysis of Variance', 'Animals', 'Antigens, Differentiation, B-Lymphocyte', 'Biomarkers', 'Cells, Cultured', 'Flow Cytometry', 'Gene Expression Regulation', 'Histocompatibility Antigens Class II', 'Humans', 'Immunity, Innate', 'Intercellular Adhesion Molecule-1', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred C57BL', ... | 30,948,627 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D23.050.301.264.051', 'D23.101.100.150'], ['D23.101'], ['A11.251'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bilateral ureteropelvic junction stenosis causing hydronephrosis and renal failure in an adult cat. | A 3.5-year-old male neutered cat was presented for investigation of renomegaly appreciated during a routine physical examination. Marked renomegaly due to bilateral hydronephrosis was detected and further testing identified International Renal Interest Society stage 2, non-hypertensive, non-proteinuric chronic kidney d... | ['Animals', 'Cat Diseases', 'Cats', 'Fatal Outcome', 'Hydronephrosis', 'Kidney Failure, Chronic', 'Kidney Pelvis', 'Male', 'Ureteral Diseases'] | 22,914,571 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C12.777.419.307', 'C13.351.968.419.307'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['A05.810.453.537'], ['C12... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of prostaglandin F2 alpha and oxytocin on bovine myometrium in vitro. | Uterine strips were collected from cows during the follicular and the luteal phases as well as from cows with ovarian cysts. The strips were mounted in organ baths and the motility was recorded by a polygraph. After the spontaneous motility of the strips had reached a steady state the test substances PGF2 alpha and oxy... | ['Animals', 'Cattle', 'Cattle Diseases', 'Estrus', 'Female', 'In Vitro Techniques', 'Ovarian Cysts', 'Oxytocin', 'Pregnancy', 'Prostaglandins F', 'Uterine Contraction'] | 7,195,017 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['G08.686.195.500'], ['E05.481'], ['C04.182.612', 'C13.351.500.056.630.580', 'C19.391.630.580'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['G08.686.784.769'], ['D10.251.355.255.550.400', 'D23.469.050.175.725.400'], ['G08.686.784.769.326.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new method of magnifying photographic images using the scanning electron microscope in the backscattered electron detection mode. | This paper describes a new method of magnifying small images in photographic film by means of a scanning electron microscope (SEM) operated in the backscattered electron detection mode. The study included tests of several types of radiographic film, transmission electron microscopy film, and black and white 35 mm film.... | ['Breast Diseases', 'Calcinosis', 'Electrons', 'Humans', 'Microscopy, Electron, Scanning', 'Scattering, Radiation', 'X-Ray Film'] | 7,170,609 | [['C17.800.090'], ['C18.452.174.130'], ['G01.249.335', 'G01.358.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E05.196.822', 'G01.867'], ['E07.960']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of three patients with a very mild form of Smith-Lemli-Opitz syndrome. | Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive malformation syndrome characterized by mental retardation, congenital anomalies, and growth deficiency. The syndrome is caused by a block in cholesterol biosynthesis at the level of 7-dehydrocholesterol reductase (7-DHCR), which results in elevated levels of t... | ['Adolescent', 'Child', 'Cholestadienols', 'Cholesterol', 'DNA Mutational Analysis', 'Dehydrocholesterols', 'Female', 'Humans', 'Infant', 'Male', 'Oxidoreductases Acting on CH-CH Group Donors', 'Smith-Lemli-Opitz Syndrome'] | 12,949,967 | [['M01.060.057'], ['M01.060.406'], ['D04.210.500.247.222.222.347'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.393.760.700.300'], ['D04.210.500.247.222.222.347.200', 'D04.210.500.247.808.197.250', 'D10.570.938.208.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.70... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A direct brainstem-amygdala-cortical 'alarm' system for subliminal signals of fear. | We examined whether consciously undetected fear signals engage a collateral brainstem pathway to the amygdala and prefrontal cortex in the intact human brain, using functional neuroimaging. 'Blindsight' lesion patients can respond to visual fear signals independently from conscious experience, suggesting that these sig... | ['Adult', 'Amygdala', 'Arousal', 'Attention', 'Awareness', 'Brain Mapping', 'Brain Stem', 'Cerebral Cortex', 'Discrimination Learning', 'Dominance, Cerebral', 'Echo-Planar Imaging', 'Fear', 'Female', 'Frontal Lobe', 'Gyrus Cinguli', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Imaging, Three-D... | 15,588,615 | [['M01.060.116'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['F02.830.104', 'G11.561.035'], ['F02.830.104.214'], ['F02.463.188.150'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132'], ['A08.186.211.200.885.287.500'], ['F02.463.425.280'], ['F02.830.297', 'G... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
CONSTANS Controls Floral Repression by Up-Regulating VERNALIZATION2 (VRN-H2) in Barley. | In barley (Hordeum vulgare), PHOTOPERIOD1 (Ppd-H1) acts as a major positive regulator of flowering under long-day conditions, while VERNALIZATION2 (VRN-H2) is a strong repressor of flowering under long days before vernalization. By contrast, CONSTANS (CO) plays a key role in the photoperiodic regulation of flowering in... | ['Arabidopsis Proteins', 'DNA-Binding Proteins', 'Flowers', 'Gene Expression Regulation, Plant', 'Hordeum', 'Photoperiod', 'Plant Proteins', 'Plants, Genetically Modified', 'Transcription Factors', 'Up-Regulation'] | 26,556,793 | [['D12.776.765.149'], ['D12.776.260'], ['A18.024.249.500'], ['G05.308.375'], ['B01.650.940.800.575.912.250.822.481'], ['G01.910.675'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['D12.776.930'], ['G02.111.905', 'G05.308.850', 'G07.690.773.998']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex. | Initiation of eukaryotic DNA replication requires phosphorylation of the MCM complex by Dbf4-dependent kinase (DDK), composed of Cdc7 kinase and its activator, Dbf4. We report here that budding yeast Rif1 (Rap1-interacting factor 1) controls DNA replication genome-wide and describe how Rif1 opposes DDK function by dire... | ['Cell Cycle Proteins', 'DNA Replication', 'Minichromosome Maintenance Proteins', 'Mutation', 'Phosphorylation', 'Protein Phosphatase 1', 'Protein Structure, Tertiary', 'Protein-Serine-Threonine Kinases', 'Repressor Proteins', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Telomere-Binding Proteins',... | 24,532,715 | [['D12.776.167'], ['G02.111.225', 'G05.226'], ['D08.811.277.040.025.159.186', 'D08.811.399.340.186', 'D12.776.167.409', 'D12.776.660.235.500', 'D12.776.664.235.750'], ['G05.365.590'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D08.811.277.352.650.625.687'], ['G02.111.570.820.709.610'], ['D08.811.913.696.620.682.700']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Monkey saccadic latency and pursuit velocity show a preference for upward directions of target motion. | Saccadic latency was studied as a function of the direction of sudden target displacements (steps) and of subsequent smooth target motion (ramps) in Macaca fascicularis. The monkey fixated a central spot that suddenly changed its position and then moved constantly at 10 deg s-1, thus eliciting initial saccades and subs... | ['Animals', 'Fixation, Ocular', 'Macaca fascicularis', 'Motion Perception', 'Photic Stimulation', 'Saccades'] | 8,730,793 | [['B01.050'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['F02.463.593.932.567'], ['E05.723.729'], ['G14.350.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overlap syndromes with sarcoidosis. | It is hoped that readers of this article will make a note of any other disorders which occur in their patients with sarcoidosis. We shall welcome this list and the frequency with which other disorders coincide with sarcoidosis. | ['Amyloidosis', 'Arthritis, Rheumatoid', 'Autoimmune Diseases', 'Celiac Disease', 'Crohn Disease', 'Female', 'Humans', 'Liver Cirrhosis, Biliary', 'Male', 'Sarcoidosis', "Sjogren's Syndrome", 'Thyroid Diseases'] | 3,843,140 | [['C18.452.845.500'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C20.111'], ['C06.405.469.637.250', 'C18.452.603.250'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.130.120.135.250.250', 'C06.552.150.250', 'C06.552.630.400', 'C23.550... | ['Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postweaning age effects on rumen fermentation end-products and digesta kinetics in calves weaned at 5 weeks of age. | Four rumen-cannulated calves were used in a block design to study changes in rumen fermentation end-products and rumen digesta kinetics after weaning. Calves were weaned at 5 wk of age and had access to dry feed from d 3 of age. Dietary DM consisted of 85% concentrate and 15% forage. The experiment was divided into thr... | ['Aging', 'Ammonia', 'Animals', 'Cattle', 'Diet', 'Digestion', 'Fatty Acids, Volatile', 'Fermentation', 'Hydrogen-Ion Concentration', 'Kinetics', 'Male', 'Nitrogen', 'Rumen', 'Weaning', 'Weight Gain'] | 8,227,677 | [['G07.345.124'], ['D01.362.075', 'D01.625.050'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['G07.203.650.250', 'G10.261.190'], ['D10.251.400'], ['G02.111.158.249', 'G03.191.249'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D01.268.604', 'D01.362.625'], ['A13.869.804'], ['G07.203.65... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Weep for Adonais. | A 1995 motor-vehicle crash brought a tragic end to the promising medical career of Michael Agapitos, a specialist in physical medicine and rehabilitation who graduated from the University of Ottawa in 1982. The death of the popular young Ottawa physician and the subsequent court case involving the driver of the other v... | ['Accidents, Traffic', 'History, 20th Century', 'Ontario', 'Physical and Rehabilitation Medicine'] | 9,084,401 | [['N06.850.135.392'], ['K01.400.504.968'], ['Z01.107.567.176.639'], ['H02.403.680']] | ['Health Care [N]', 'Humanities [K]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Effects of nicorandil on the conductive coronary artery of the dog. | The effects of nicorandil (2-nicotinamidoethyl nitrate, SG-75) on the conductive coronary artery were studied and compared with the effects of nitroglycerin and nifedipine. In isolated perfused canine heart preparations with a support dog, nicorandil produced a decrease in the resistance of the conductive coronary arte... | ['Animals', 'Coronary Vessels', 'Dogs', 'Female', 'In Vitro Techniques', 'Lanthanum', 'Male', 'Muscle, Smooth, Vascular', 'Niacinamide', 'Nicorandil', 'Nifedipine', 'Nitroglycerin', 'Perfusion', 'Potassium', 'Vasoconstriction', 'Vasodilator Agents'] | 2,447,415 | [['B01.050'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.481'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D03.066.515.530', 'D03.383.725.547.530'], ['D02.583.575', 'D03.066.515.530.498', 'D03.383.725.547.5... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Possible function of matrix proteins in fluoride incorporation into enamel mineral during porcine amelogenesis. | The present study was undertaken to elucidate the mechanism of fluoride incorporation into secretory enamel mineral, with porcine enamel used as a model. Although the fluoride content in the enamel varied greatly among the animals, we observed that the fluoride-to-calcium ratio in the enamel tissue was maximal at the b... | ['Amelogenesis', 'Amelogenin', 'Animals', 'Calcium', 'Dental Enamel', 'Dental Enamel Proteins', 'Durapatite', 'Fluorides', 'Hydroxyapatites', 'Swine'] | 2,561,129 | [['G07.345.500.325.377.750.190'], ['D12.776.231.500'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A14.549.167.900.255'], ['D12.776.231'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['D01.248.497.158.380... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pre-diagnostic smoking behaviour and poorer prognosis in a German breast cancer patient cohort - Differential effects by tumour subtype, NAT2 status, BMI and alcohol intake. | BACKGROUND: Inconsistent associations of smoking and breast cancer-specific mortality might be explained by subgroups of patients with different susceptibility to harmful effects of smoking.METHODS: We used a prospective cohort of 3340 postmenopausal breast cancer patients aged 50-74 and diagnosed with invasive tumours... | ['Aged', 'Alcohol Drinking', 'Arylamine N-Acetyltransferase', 'Body Mass Index', 'Breast Neoplasms', 'Cohort Studies', 'European Continental Ancestry Group', 'Female', 'Genotype', 'Germany', 'Humans', 'Kaplan-Meier Estimate', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Polymorphism, Single Nucleotide', 'Prognosis', '... | 24,950,597 | [['M01.060.116.100'], ['F01.145.317.269'], ['D08.811.913.050.134.138'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['M01.686.508.400'], ['G05.380'], ['Z01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Determination of iron species in wine by ion-exchange chromatography--flame atomic absorption spectrometry. | The direct coupling of ion-exchange chromatography to flame atomic absorption spectrometry (AAS) has been achieved by employing a Babington type nebuliser. The system enables all the processes on the column to be followed directly at flow-rates of between 1 and 5 ml min-1. The potential of the system was investigated f... | ['Chromatography, Ion Exchange', 'Iron', 'Spectrophotometry, Atomic', 'Wine'] | 2,712,313 | [['E05.196.181.400.383'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['E05.196.712.726.551', 'E05.196.867.826.551'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02.200.100.900', 'J02.350.887']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Killing times of minke whales in the Norwegian coastal whaling in the 1981 and 1982 seasons. | During the whaling seasons of 1981 and 1982 16 inspectors were on the whaling grounds to collect data about weapons and equipment, shooting facilities, hitting areas, reaction to hits, tissue and organ damage and killing times. The inspectors were instructed to confirm the criteria of death by personal observation befo... | ['Animals', 'Cetacea', 'Death', 'Equipment and Supplies', 'Ethics', 'Fisheries', 'Norway', 'Seasons', 'Time Factors', 'Whales'] | 6,647,025 | [['B01.050'], ['B01.050.150.900.649.313.875'], ['C23.550.260'], ['E07'], ['K01.752.566.479', 'N05.350'], ['J01.040.168.300', 'J03.540.280'], ['Z01.542.816.374'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.910.857'], ['B01.050.150.900.649.313.875.865']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Factors in Patient Empowerment: A Survey of an Online Patient Research Network. | BACKGROUND: Providers and healthcare organizations have begun recognizing the importance of patient empowerment as a driver of patient-centered care. Unfortunately, most studies have investigated empowerment with single diseases. Identifying factors of empowerment across conditions and populations would enable a greate... | ['Chronic Disease', 'Humans', 'Internet', 'Male', 'Patient Participation', 'Patient-Centered Care', 'Power, Psychological'] | 27,155,887 | [['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.540.245.360.300', 'N05.300.150.800.500.620'], ['N04.590.233.727.407'], ['F01.658.780']] | ['Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function. | AIMS: Growth factors play an important role in regulating vascular function. Data are limited regarding clinical and genetic correlates of endothelial growth factors and their associations with vascular function.METHODS AND RESULTS: We evaluated clinical and genetic correlates of circulating vascular endothelial growth... | ['Adult', 'Cardiovascular Diseases', 'Cross-Sectional Studies', 'Female', 'Hepatocyte Growth Factor', 'Humans', 'Male', 'Middle Aged', 'Parents', 'Pedigree', 'Quantitative Trait, Heritable', 'Vascular Endothelial Growth Factor A', 'Vascular Endothelial Growth Factor Receptor-1'] | 19,223,316 | [['M01.060.116'], ['C14'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D12.644.276.374.420', 'D12.776.467.374.420', 'D23.529.374.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.393.673'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Pericranium graft in reconstructive surgery of atrophied maxillary bones. | In preprosthetic surgery the autologous bone is universally considered the gold standard. Calvaria is, among many options, one of the preferred for its unique characteristics of hardness, easy of harvest and very low morbidity at donor site. Moreover, it gives the possibility of harvesting the pericranium. This techniq... | ['Adult', 'Aged', 'Alveolar Bone Loss', 'Alveolar Ridge Augmentation', 'Atrophy', 'Female', 'Fistula', 'Humans', 'Male', 'Mandibular Fractures', 'Mandibular Prosthesis', 'Maxilla', 'Maxillary Fractures', 'Maxillofacial Prosthesis', 'Middle Aged', 'Nose Diseases', 'Odontogenic Cysts', 'Oral Fistula', 'Parietal Bone', 'P... | 18,496,488 | [['M01.060.116'], ['M01.060.116.100'], ['C05.116.264.150', 'C07.465.714.354.500'], ['E04.545.550.100', 'E06.645.550.100'], ['C23.300.070'], ['C23.300.575'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.900.300.284.500.400.255', 'C26.404.750.467.441', 'C26.915.300.425.500.400.255'], ['E07.695.510.500'], ['A02.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association of the circadian rhythmic expression of GmCRY1a with a latitudinal cline in photoperiodic flowering of soybean. | Photoperiodic control of flowering time is believed to affect latitudinal distribution of plants. The blue light receptor CRY2 regulates photoperiodic flowering in the experimental model plant Arabidopsis thaliana. However, it is unclear whether genetic variations affecting cryptochrome activity or expression is broadl... | ['Arabidopsis', 'Arabidopsis Proteins', 'Base Sequence', 'Circadian Rhythm', 'Cryptochromes', 'Flavoproteins', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Molecular Sequence Data', 'Plant Proteins', 'Proteasome Endopeptidase Complex', 'Soybeans'] | 19,106,300 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G07.180.562.190'], ['D12.644.360.138.150', 'D12.776.331.180', 'D12.776.476.156.250', 'D12.776.765.593.500'], ['D12.776.331'], ['G05.308.320'], ['G05.308.375'], ['L01.453.245.667'], ['D12.776.765']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mammosomatotroph adenoma cells secrete both growth hormone and prolactin. | Pituitary adenoma cells from a mammosomatotroph adenoma obtained from a 21-year-old female presenting with acromegaly and amenorrhea were investigated by sandwich cell immunoblot assay, immunohistochemistry, and electron microscopy. The new, simple technique of sandwich cell immunoblot assay could detect two hormones s... | ['Adenoma', 'Adult', 'Female', 'Growth Hormone', 'Humans', 'Immunoblotting', 'Pituitary Gland', 'Pituitary Neoplasms', 'Prolactin'] | 8,657,329 | [['C04.557.470.035'], ['M01.060.116'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.200.317.357.352.435.500', 'A08.713.357.750'], ['C04.5... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of angiotensin-converting enzyme inhibition throughout a superovulation protocol in ewes. | Many studies identified new components of the renin–angiotensin system (RAS), such as Angiotensin-(1-7) [Ang-(1–7)] and Angiotensin-converting enzyme type 2 (ACE2), in mammalian ovaries.We previously showed Angiotensin-Converting Enzyme (ACE) inhibition, which increases the level of Ang-(1–7), stimulated ovarian estrad... | ['Angiotensin I', 'Angiotensin II', 'Angiotensin-Converting Enzyme 2', 'Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Embryo, Nonmammalian', 'Enalapril', 'Estradiol', 'Female', 'Ovulation', 'Peptide Fragments', 'Peptidyl-Dipeptidase A', 'Progesterone', 'Sheep', 'Superovulation'] | 26,679,819 | [['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D08.811.277.656.350.245.042']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Label-free detection of micro-RNA hybridization using surface-enhanced Raman spectroscopy and least-squares analysis. | Label-free surface-enhanced Raman spectroscopy (SERS) detection of nucleic acid hybridization is impeded by poor spectral reproducibility and the fact that the chemical signatures of hybridized and unhybridized sequences are highly similar. To overcome these issues, highly reproducible silver nanorod SERS substrates al... | ['Least-Squares Analysis', 'MicroRNAs', 'Nanotubes', 'Nucleic Acid Hybridization', 'Silver', 'Spectrum Analysis, Raman'] | 22,788,749 | [['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['J01.637.512.850'], ['E05.393.661', 'G02.111.611'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['E05.196.822.860', 'E05.196.867.890']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Antitumor activity and biochemical effects of cyclopentenyl cytosine in mice. | Cyclopentenyl cytosine, a recently synthesized inhibitor of cytidine 5'-triphosphate synthesis, has marked antitumor activity. Treatment with 1 mg/kg i.p. on days 1-9 following inoculation with tumor produced 111-122% increased median life span in mice bearing L1210 leukemia, 73-129% increased median life span in mice ... | ['Animals', 'Cells, Cultured', 'Cytidine', 'Cytosine Nucleotides', 'Dose-Response Relationship, Drug', 'Leukemia L1210', 'Leukemia P388', 'Melanoma', 'Mice', 'Neoplasms, Experimental'] | 3,708,566 | [['B01.050'], ['A11.251'], ['D03.383.742.680.245', 'D13.570.685.245', 'D13.570.800.286'], ['D03.383.742.686.246', 'D13.695.740.246', 'D13.695.827.232'], ['G07.690.773.875', 'G07.690.936.500'], ['C04.557.337.372.594', 'C04.619.531.594'], ['C04.557.337.372.782', 'C04.619.531.782'], ['C04.557.465.625.650.510', 'C04.557.58... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic regulation of ionizing radiation sensitivity and breast cancer risk. | Genetic variability in DNA repair may contribute to hypersensitivity to ionizing radiation (IR) and susceptibility to breast cancer. We used samples collected from a clinic-based breast cancer case-control study to test the working hypothesis that amino acid substitution variants of DNA repair genes may contribute to p... | ['Adolescent', 'Adult', 'Aged', 'Amino Acid Substitution', 'Breast Neoplasms', 'Carbon-Oxygen Lyases', 'Case-Control Studies', 'DNA Repair', 'DNA, Neoplasm', 'DNA-(Apurinic or Apyrimidinic Site) Lyase', 'DNA-Binding Proteins', 'Female', 'G2 Phase', 'Genotype', 'Humans', 'Middle Aged', 'Polymerase Chain Reaction', 'Poly... | 11,921,191 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.393.420.601.035', 'G05.558.109'], ['C04.588.180', 'C17.800.090.500'], ['D08.811.520.241'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G02.111.222', 'G05.219'], ['D13.444.308.425'], ['D08.811.074.750', 'D08.811.520.241.22... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Application of Rogerson spatial pattern surveillance in monitoring infectious diseases: parameter setting and choice of scales of analysis]. | OBJECTIVE: To set up appropriate parameters and scales of analysis for monitoring infectious diseases using Rogerson spatial pattern surveillance method.METHODS: Hepatitis data in Henan provinces from 2006 to 2009 were tested using Rogerson spatial patterns surveillance method.RESULTS: When the parameters were set with... | ['China', 'Cluster Analysis', 'Communicable Diseases', 'Computer Simulation', 'Data Interpretation, Statistical', 'Hepatitis A', 'Humans', 'Models, Statistical', 'Population Surveillance'] | 21,866,646 | [['Z01.252.474.164'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['C01.221', 'C23.550.291.531'], ['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C01.925.440.420', 'C01.925.782.687.359.500', 'C06.552.380.705.422'], ['... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Splint renal function after captopril in unilateral renal artery stenosis. | The renal extraction ratios of 131I-sodium iodohippurate (131I-Hippuran) and 125I-thalamate were greatly reduced on the affected side by 50 mg captopril in seven out of 14 patients with unilateral renal artery stenosis. With long term captopril 150 mg daily the uptake of 99mTc-diethylenetriaminepenta-acetic acid by the... | ['Adult', 'Aged', 'Captopril', 'Female', 'Humans', 'Hypertension, Renovascular', 'Iodine Radioisotopes', 'Iodohippuric Acid', 'Kidney', 'Male', 'Middle Aged', 'Pentetic Acid', 'Proline', 'Radioisotope Renography', 'Renal Artery Obstruction', 'Technetium', 'Technetium Tc 99m Pentetate', 'Time Factors'] | 6,423,129 | [['M01.060.116'], ['M01.060.116.100'], ['D12.125.072.401.623.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.331.490', 'C13.351.968.419.331.490', 'C14.907.489.631.485'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D02.065.277.431.579', 'D02.241.223.100.100.400.500', 'D02.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Utility of routine evaluation of sterility of cellular therapy products with or without extensive manipulation: Best practices and clinical significance. | BACKGROUND: We analyzed the results of routine sterility testing performed in our center over the last 10 years, in the context both hematopoietic stem cell transplantation (HSCT) and Advanced Therapeutic Medicinal Products (ATMPs).METHODS: For sterility tests 14-day cultures were performed in culture media detecting a... | ['Blood Component Removal', 'Cell- and Tissue-Based Therapy', 'Culture Media', 'Hematopoietic Stem Cell Transplantation', 'Hematopoietic Stem Cells', 'Humans', 'Mesenchymal Stem Cells', 'Sterilization', 'Time Factors'] | 29,246,649 | [['E02.120'], ['E02.095.147'], ['D27.720.470.305', 'E07.206'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['N06.850.780.200.450.850'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Laparoscopic pelvic lymph node dissection, laparoscopically assisted seminal vesicle mobilization, and total perineal prostatectomy versus radical retropubic prostatectomy for prostate cancer. | OBJECTIVES: The outcomes of patients with prostate cancer who were candidates for radical prostatectomy were compared with patients who underwent either: (1) radical retropubic prostatectomy (RRP); or (2) laparoscopic pelvic lymph node dissection, laparoscopically assisted seminal vesicle mobilization, and total perine... | ['Aged', 'Biopsy', 'Blood Loss, Surgical', 'Follow-Up Studies', 'Humans', 'Laparoscopy', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Pelvis', 'Postoperative Care', 'Postoperative Complications', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prosta... | 7,538,244 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C23.550.414.300', 'C23.550.505.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of recombinant human lactoferrin secreted in milk of transgenic mice. | Human lactoferrin (hLF) is an iron-binding protein involved in host defense against infection and severe inflammation. Transgenic mice were produced harboring either hLF cDNA or genomic hLF sequences fused to regulatory elements of the bovine alphaS1 casein gene. Recombinant hLF expressed in the milk of transgenic mice... | ['Animals', 'Cattle', 'Chromatography, Gel', 'DNA, Complementary', 'Electrophoresis, Polyacrylamide Gel', 'Glycosylation', 'Humans', 'Iron', 'Lactoferrin', 'Mice', 'Mice, Transgenic', 'Milk', 'Radioimmunoassay', 'Recombinant Proteins'] | 9,079,716 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.250'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Endothelium-dependent contractions occur in the aorta of wild-type and COX2-/- knockout but not COX1-/- knockout mice. | The present experiments were designed to determine whether or not endothelium-dependent contractions can be evoked in the aorta of the mouse, and if so, whether or not deleting the COX1 gene affects the response. Sex differences in the response were also examined. Rings of murine aorta were suspended in a Halpern-Mulva... | ['Animals', 'Aorta', 'Calcimycin', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Endothelins', 'Endothelium, Vascular', 'Female', 'In Vitro Techniques', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'NG-Nitroarginine Methyl Ester', 'Sex Characteristics', 'Vasoconstriction'] | 16,306,799 | [['B01.050'], ['A07.015.114.056'], ['D03.633.100.221.173'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['A07.015.700.500', 'A10.272.491.355'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Chemical Constituents from Caragana changduensis]. | Objective: To study the chemical constituents of the red heartwood of the stems and roots of Caragana changduensis.Methods: The chemical constituents were isolated and purified by means of several column chromatographic techniques,and their structures were determined by spectroscopic methods.Results: Ten compounds were... | ['Caragana', 'Flavanones', 'Oleanolic Acid', 'Plant Roots', 'Pterocarpans', 'Sitosterols'] | 30,079,714 | [['B01.650.940.800.575.912.250.401.098'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['D02.455.849.919.530.733', 'D02.455.849.919.650.600'], ['A18.400'], ['D03.383.663.283.266.450.400.687', 'D03.633.100.127.637', 'D03.633.100.150.266.450.400.687', 'D03.633.400.748'], ['D04.210.500.247.222.857', 'D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laparoscopic liver biopsy performed safely in a child with hepatic dysfunction: report of a case. | We performed laparoscopic liver biopsy in a 10-year-old girl with acute myelocytic leukemia and coagulopathy. Each biopsy was taken under laparoscopic ultrasound (LUS) guidance, and hemostasis was achieved with an argon beam coagulator (ABC). These instruments were introduced through one 10/12-mm port, which also allow... | ['Biopsy', 'Bone Marrow Transplantation', 'Child', 'Female', 'Graft vs Host Disease', 'Hemostasis', 'Humans', 'Laparoscopy', 'Laser Coagulation', 'Leukemia, Myeloid, Acute', 'Liver Diseases'] | 12,928,853 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.060.406'], ['C20.452'], ['G09.188.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of the fluorescent antibody test to detect Escherichia coli with K88 and 987P pilus antigens. | Direct fluorescent antibody tests were used to detect Escherichia coli possessing K88 and 987P antigens. Identification of bacteria was accomplished on suspensions of organisms from clinical isolates, on frozen sections and impression smears from small intestine and on faecal smears. This assay makes possible the rapid... | ['Adhesins, Escherichia coli', 'Animals', 'Antigens, Bacterial', 'Antigens, Surface', 'Escherichia coli', 'Escherichia coli Infections', 'Escherichia coli Proteins', 'Fimbriae Proteins', 'Fimbriae, Bacterial', 'Fluorescent Antibody Technique', 'Swine', 'Swine Diseases'] | 2,871,657 | [['D12.776.097.120.050.040', 'D12.776.097.275.500', 'D12.776.543.100.050.040', 'D23.050.161.050.040'], ['B01.050'], ['D23.050.161'], ['D23.050.301'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['D12.776.097.275'], ['D12.776.097.120.425', 'D12.776.543.100.300'], ['A11.284.180.28... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physicians' non-compliance with patients' refusal of life-sustaining treatment. | Should patients be treated when they have specifically refused treatment? Three competent patients are described with end-stage renal disease who, against the advice of their family, friends and care-givers, refused dialysis. Each was treated and subsequently they acknowledged their satisfaction with the outcome. Guide... | ['Adult', 'Aged', 'Cooperative Behavior', 'Ethics, Medical', 'Euthanasia, Passive', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Paternalism', 'Patient Advocacy', 'Personal Autonomy', 'Physician-Patient Relations', 'Renal Dialysis'] | 3,688,043 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.813.115'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['E02.760.905.199.500', 'E02.760.952.500', 'N02.421.585.905.199.625', 'N02.421.585.952.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Minimal metastatic and minimal residual disease in patients with Ewing tumors]. | At least 95% of Ewing tumors (ET) are characterized by an EWS-gene rearrangement with either FLI-1 or ERG and by extraordinary high MIC2/CD99 expression. Both features can be used for the specific identification of tumor cells, which might also be present in blood and bone marrow in minimal metastatic or minimal residu... | ['Adolescent', 'Biomarkers, Tumor', 'Biopsy', 'Bone Marrow', 'Bone Marrow Neoplasms', 'Bone Neoplasms', 'Bone and Bones', 'Cell Line', 'Child', 'Female', 'Fluorescent Antibody Technique', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'Neoplasm, Residual', 'Neoplastic Cells, Circulating', 'Polymerase Chain... | 7,564,161 | [['M01.060.057'], ['D23.101.140'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A15.382.216'], ['C04.588.448.200', 'C15.378.190.250', 'C15.378.400.200'], ['C04.588.149', 'C05.116.231'], ['A02.835.232', 'A10.165.265'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Changes in the factor VIII molecular complex in Hodgkin's disease and non-Hodgkin's lymphoma]. | Factor VIII molecular complex is included in the proteins of "acute inflammation", being changed not only in the congenital diseases - hemophilia A and Willebrand disease but also in a series of acquired diseases as various inflammatory processes, hypercoagulability, DIC syndrome, neoplasms. The studies carried out on ... | ['Factor VIII', 'Fibrinogen', 'Hodgkin Disease', 'Humans', 'Lymphoma, Non-Hodgkin', 'von Willebrand Factor'] | 3,113,078 | [['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.48... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of untreated and treated temporomandibular joint arthritis on mandibular volume development in growing rabbits. | OBJECTIVES: The goal of this work was to investigate the volume development of the mandible in growing rabbits with bilaterally induced temporomandibular joint (TMJ) arthritis that was either left untreated or treated with the tumor necrosis factor-alpha (TNF-á) antagonist etanercept.METHODS: A total of 18 New Zealand ... | ['Aging', 'Animals', 'Antirheumatic Agents', 'Arthritis', 'Etanercept', 'Female', 'Mandible', 'Organ Size', 'Rabbits', 'Reference Values', 'Temporomandibular Joint Disorders', 'Treatment Outcome'] | 25,929,713 | [['G07.345.124'], ['B01.050'], ['D27.505.954.329'], ['C05.550.114'], ['D12.644.541.500.697.624', 'D12.776.124.486.485.538.500.624', 'D12.776.124.486.485.680.697.624', 'D12.776.124.790.651.538.500.624', 'D12.776.124.790.651.680.660.624', 'D12.776.377.715.548.538.500.624', 'D12.776.377.715.548.680.660.624', 'D12.776.543.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Antibiotic-associated diarrhea and the older dental patient: how do dentists respond? | BACKGROUND: Gastrointestinal complications from antibiotic use, including Clostridium difficile infection (CDI), can have significant morbidity, especially among older patients. This descriptive study surveyed dentists to find out how they would respond to a patient with signs indicating potential CDI.METHODS: A survey... | ['Aged', 'Anti-Bacterial Agents', 'Clostridioides difficile', 'Decision Making', 'Dental Care for Aged', 'Diarrhea', 'Enterocolitis, Pseudomembranous', 'Female', 'Humans', 'Male', 'Middle Aged', 'New Jersey', "Practice Patterns, Dentists'"] | 26,297,332 | [['M01.060.116.100'], ['D27.505.954.122.085'], ['B03.353.625.657.500'], ['F02.463.785.373'], ['E06.170.100', 'N02.421.240.190.210'], ['C23.888.821.214'], ['C01.150.252.410.222.310', 'C06.405.205.596.800', 'C06.405.469.363.800'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.567.875.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
New trends in early diagnosis of hydroxychloroquine toxic retinopathy. | BACKGROUND: Toxic retinopathy is an uncommon sequella in the treatment of certain autoimmune diseases with hydroxychloroquine (HCQ). We present two cases of HCQ toxic retinopathy, as well as a discussion on how to diagnose and manage early toxicity findings;CASE REPORTS: Two cases are presented of patients who experie... | ['Aged', 'Aged, 80 and over', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Diagnosis, Differential', 'Early Diagnosis', 'Electroretinography', 'Follow-Up Studies', 'Humans', 'Hydroxychloroquine', 'Male', 'Retina', 'Retinal Diseases', 'Tomography, Optical Coherence', 'Visual Fields'] | 23,249,122 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E01.171'], ['E01.390'], ['E01.370.380.225', 'E01.370.405.270'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Alkaline phosphatase (ALP) enhancing iridoid glucosides from the Indonesian medicinal plant Barleria lupulina. | In order to find antiosteoporotic agents from natural resources, 32 Indonesian medicinal plants were screened for their effects on osteoblast differentiation by using alkaline phosphatase (ALP) activity in MC3T3-E1 osteoblast cells as a marker. From the extract of Barleria lupulina, which showed the most potent activit... | ['3T3 Cells', 'Acanthaceae', 'Alkaline Phosphatase', 'Animals', 'Indonesia', 'Iridoid Glucosides', 'Mice', 'Molecular Structure', 'Plants, Medicinal', 'Structure-Activity Relationship'] | 21,213,964 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.650.940.800.575.912.250.583.040'], ['D08.811.277.352.650.035'], ['B01.050'], ['Z01.252.145.380', 'Z01.639.580'], ['D02.455.426.392.368.450.675.500.500.500', 'D02.455.849.575.188.500.500.500', 'D03.383.663.491.500.500', 'D09.408.348.387', 'D09.408.423.500'], ['B01.050.150.9... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[Imagiology of the acute calcific tendinitis of the longus colli]. | The acute calcific tendinitis of the longus colli, it's a rare nosologic condition, that generally presents with intense and sudden neck pain,associated with dysphagia, little time after an effort or local trauma, with rapidly symptomatic progression, that in just a few days tend to totally limit the normal function. T... | ['Acute Disease', 'Calcinosis', 'Female', 'Humans', 'Middle Aged', 'Neck Muscles', 'Tendinopathy', 'Tomography, X-Ray Computed'] | 23,177,585 | [['C23.550.291.125'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567.650'], ['C05.651.869', 'C26.874.800'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Physical performance across the thyroid function values within the normal range in adult and older persons. | BACKGROUND: Thyroid hormone variation may be correlated with adverse health outcomes, even within the normal reference range in euthyroid individuals.AIMS: To determine the association between plasma thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) levels and physical performance... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Physical Functional Performance', 'Reference Values', 'Thyroid Gland', 'Thyrotropin', 'Thyroxine', 'Triiodothyronine', 'Young Adult'] | 29,845,558 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N01.400.545.750'], ['E05.978.810'], ['A06.300.900'], ['D06.472.699.631.525.883', 'D12.644.548.691.525.883... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Helicobacter Pylori's plasticity zones are novel transposable elements. | BACKGROUND: Genes present in only certain strains of a bacterial species can strongly affect cellular phenotypes and evolutionary potentials. One segment that seemed particularly rich in strain-specific genes was found by comparing the first two sequenced Helicobacter pylori genomes (strains 26695 and J99) and was name... | ['Animals', 'Base Sequence', 'Cell Line', 'Cytokines', 'DNA Transposable Elements', 'DNA, Bacterial', 'Gene Deletion', 'Genes, Bacterial', 'Genome, Bacterial', 'Helicobacter pylori', 'Humans', 'Mice', 'Molecular Sequence Data', 'Multigene Family', 'Phylogeny', 'Sequence Analysis, DNA'] | 19,727,398 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D13.444.308.212'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Salivary IgA levels and infection risk in elite swimmers. | UNLABELLED: The effects of exercise on the immune system has been shown to be dependent on the level of fitness of the subjects, the degree of intensity, and the duration of the exercise. A reduction in salivary IgA levels occurs after individual sessions of exercise.PURPOSE: The purpose of this study was to assess the... | ['Adolescent', 'Adult', 'Biomarkers', 'Cohort Studies', 'Female', 'Humans', 'Immunoglobulin A, Secretory', 'Incidence', 'Infections', 'Male', 'Prognosis', 'Risk Assessment', 'Saliva', 'Stress, Psychological', 'Swimming'] | 9,927,012 | [['M01.060.057'], ['M01.060.116'], ['D23.101'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026.030', 'D12.776.124.790.651.114.619.026.030', 'D12.776.377.715.548.114.619.026.030'], ['E05.318.308.985.525.375... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Personalismo and breaking barriers: accessing Hispanic populations for clinical services and research. | Thirteen percent of Hispanic households provide care to an adult aged 50 or older, but given their dramatic population growth, an increasingly large number of families will soon be placed in a caregiving role. The purpose of this study was to determine whether Hispanic caregivers could be accessed through local provide... | ['Adult', 'Aged', 'Arizona', 'Attitude of Health Personnel', 'Attitude to Health', 'Caregivers', 'Communication', 'Cost of Illness', 'Cultural Diversity', 'Dementia', 'Empathy', 'Family', 'Female', 'Focus Groups', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Hispanic Americans', 'Home Nursing',... | 17,982,809 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.875.760.100'], ['F01.100.050', 'N05.300.100'], ['F01.100.150', 'N05.300.150'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F01.145.209', 'L01.143'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['I01.076.201.450.350'... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
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