Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Benzodiazepine/gamma-aminobutyric acid receptor deficit in the midbrain of the seizure-susceptible gerbil. | The density of benzodiazepine/gamma-aminobutyric acid receptor binding sites was lower in the midbrain of seizure-susceptible gerbils compared to control seizure-resistant gerbils. Binding of [3H]diazepam to high-affinity brain-specific sites in membrane homogenates of gerbil brain showed a 20-30% lower binding in midb... | ['Animals', 'Bicuculline', 'Diazepam', 'Disease Models, Animal', 'Flunitrazepam', 'Gerbillinae', 'Mesencephalon', 'Muscimol', 'Pentobarbital', 'Receptors, GABA-A', 'Seizures'] | 2,995,980 | [['B01.050'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['D03.633.100.079.080.070.216'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D03.633.100.079.080.070.320'], ['B01.050.150.900.649.313.992.635.300'], ['A08.186.211.132.659'], ['D03.383.129.462.470', 'D23.946.587.587'], ['D03.383.742.698.253.593'], ['D12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risperidone ameliorated Aâ1-42 | Alzheimer's disease (AD) is a complex neurodegenerative disorder with cognitive impairment and major neuropathologic hallmark of amyloid-beta (Aâ) peptides. Risperidone, an atypical antipsychotic, can improve concentration and cognitive deficit in schizophrenia patients. In this study, behavior tests including Morris W... | ['Alzheimer Disease', 'Amyloid Precursor Protein Secretases', 'Amyloid beta-Peptides', 'Animals', 'Apoptosis', 'Aspartic Acid Endopeptidases', 'Cells, Cultured', 'Cognition Disorders', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Hippocampus', 'Male', 'Mice, Inbred ICR', 'Neurons', 'Neuroprotective Ag... | 28,093,254 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D08.811.277.656.300.032'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['A11.251'], ['F03.615.250'], ['C22.232', 'E05.598.500', 'E05.599.395.... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of the effects of anatomic location, histologic processing, and sample size on shrinkage of skin samples obtained from canine cadavers. | OBJECTIVE To evaluate effects of anatomic location, histologic processing, and sample size on shrinkage of excised canine skin samples. SAMPLE Skin samples from 15 canine cadavers. PROCEDURES Elliptical samples of the skin, underlying subcutaneous fat, and muscle fascia were collected from the head, hind limb, and lumb... | ['Animals', 'Cadaver', 'Cytological Techniques', 'Dogs', 'Female', 'Histological Techniques', 'Male', 'Sample Size', 'Skin', 'Specimen Handling'] | 27,580,116 | [['B01.050'], ['C23.550.260.224'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.225.750', 'E05.200.750'], ['E05.318.370.762', 'E05.581.500.902', 'N05.715.360.325.692', 'N06.850.520.445.762'], ['A17.815'], ['E01.370.225.998', 'E05.200.998']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Orbicular muscular-mucous advancement flap for repairing the lower lip loss after lip cancer]. | OBJECTIVE: To explore a new technique for the treatment of lower lip defect after carcinoectomy.METHOD: Six lower lip defects (more than two third of the length of the lower lip) after the tumor resection were treated with an orbicular muscular-mucous advancement flap.RESULTS: All of the patients had achieved good resu... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Female', 'Humans', 'Lip', 'Lip Neoplasms', 'Male', 'Middle Aged', 'Postoperative Complications', 'Reconstructive Surgical Procedures', 'Surgical Flaps'] | 15,334,935 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.456.505.631.515', 'A14.549.336'], ['C04.588.443.591.550', 'C07.465.409.640', 'C07.465.530.550'], ['M01.060.116.630'], ['C23.550.767'], ['E04.680'], ['A10.850.710', 'E07.862.710']... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An investigation into the suitability of a commercial real-time PCR assay to screen for Taylorella equigenitalis in routine prebreeding equine genital swabs. | REASONS FOR PERFORMING STUDY: Standard bacteriological methods for identifying Taylorella equigenitalis in cervical smears are time consuming. Therefore, a more rapid real-time PCR assay was evaluated for its suitability in screening swabs.OBJECTIVE: To compare the results of a commercially available real-time PCR assa... | ['Animals', 'Female', 'Gram-Negative Bacterial Infections', 'Horse Diseases', 'Horses', 'Male', 'Polymerase Chain Reaction', 'Sexually Transmitted Diseases, Bacterial', 'Taylorella equigenitalis'] | 20,383,985 | [['B01.050'], ['C01.150.252.400'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['E05.393.620.500'], ['C01.150.252.734', 'C01.221.812.281', 'C01.778.281', 'C12.294.668.281', 'C13.351.500.711.281', 'C23.550.291.531.937.281'], ['B03.440.400.425.115.800.200', 'B03.660.075.090.344.800.200']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retrospective study of melamine/cyanuric acid-induced renal failure in dogs in Korea between 2003 and 2004. | In early 2007, American pet food ingredients leading to nephrotoxic renal failure of dogs and cats raised serious concerns about the safety of pet foods. Major pet food companies recalled more than 1,000 commercial pet foods in consideration of pet safety. A similar pet food-associated outbreak of nephrotoxic renal fai... | ['Animal Feed', 'Animals', 'Dog Diseases', 'Dogs', 'Female', 'Food Contamination', 'Kidney', 'Korea', 'Male', 'Renal Insufficiency', 'Retrospective Studies', 'Triazines'] | 19,261,650 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['A05.810.453'], ['Z01.252.474.557', 'Z01.586.407'], ['C12.777.419.780', 'C13.351.968.419.780'], ['E05.318.372.500.500.500', 'E05... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Alexithymia and somatization. | Although alexithymia was originally described in patients with classical psychosomatic illnesses, attempts to specifically correlate these illnesses with alexithymia have not been successful. Despite the prominent role of somatization in the clinical description of alexithymia, a specific correlation between alexithymi... | ['Awareness', 'Fantasy', 'Headache', 'Humans', 'Mood Disorders', 'Pain', 'Psychological Tests', 'Psychophysiologic Disorders', 'Somatoform Disorders', 'Spasm', 'Urination Disorders'] | 7,156,304 | [['F02.463.188.150'], ['F01.393.351', 'F02.463.188.634.507'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.600'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['F04.711'], ['C23.888.592.700'], ['F03.875'], ['C10.597.613.750', 'C23.888.592.608.750'], ['C12.777.934', 'C13.... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of new and conventional methods for quantification of tooth color. | Tooth color is caused by volume reflection, that is, passage of incident light through the tooth followed by backward emergence. This passage is concurrent with sideward displacement of photons that, in effect, influences the result of usual instrumental methods of determining tooth color. This problem is overcome by t... | ['Acrylic Resins', 'Color', 'Colorimetry', 'Fiber Optic Technology', 'Humans', 'Optical Fibers', 'Optics and Photonics', 'Regression Analysis', 'Spectrophotometry', 'Tooth'] | 2,304,021 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['G01.590.540.199'], ['E05.196.922.250'], ['H01.671.617.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.750'], ['H01.671.617', 'J01.293.688'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.196.71... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Partial sequencing and expression of genes involved in glucose metabolism in adipose tissues and skeletal muscle of healthy cats. | Impaired insulin sensitivity is increasingly recognised in cats, but sequences of genes involved in insulin-signalling are largely undetermined in this species. In this study, extended feline mRNA sequences were determined for the adiponectin, glucose transporter-1 (GLUT1), GLUT4, peroxisome proliferative activated rec... | ['Adipose Tissue', 'Animals', 'Blood Glucose', 'Cats', 'Energy Metabolism', 'Female', 'Gene Expression', 'Glucose Transport Proteins, Facilitative', 'Insulin', 'Insulin Resistance', 'Male', 'Muscle, Skeletal', 'PPAR gamma', 'Receptor, Insulin', 'Species Specificity'] | 18,078,768 | [['A10.165.114'], ['B01.050'], ['D09.947.875.359.448.500'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G03.295'], ['G05.297'], ['D12.776.157.530.500.500', 'D12.776.157.530.937.563', 'D12.776.543.585.500.500', 'D12.776.543.585.937.625'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.3... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Porcine alpha-1,3-galactosyltransferase: full length cDNA cloning, genomic organization, and analysis of splicing variants. | Full length cDNA and genomic DNA of porcine alpha-1,3-galactosyltransferase were isolated, and their structures were analysed. The coding region was encoded by six exons as in the mouse, and the length of each exon was conserved between the two species. The porcine exons were designated Exon 4-9, since in the mouse cod... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'COS Cells', 'Cloning, Molecular', 'DNA, Complementary', 'Exons', 'Galactosyltransferases', 'Introns', 'Mice', 'Molecular Sequence Data', 'RNA Splicing', 'Reverse Transcriptase Polymerase Chain Reaction', 'Swine'] | 9,881,764 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.172.500', 'A11.329.228.220'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.360.340.024.340.137.232'], ['D08.811.913.400.450.400'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
EMG Functional tasks recordings determines frailty phenotypes in males and females. | BACKGROUND: Identification of frailty is essential to understanding and mitigating age-related physical impairments. Previous studies have indicated that frailty phenotype can be identified through electromyography (EMG) when collected over the course of an 8-h day. However, long duration recordings challenge both the ... | ['Activities of Daily Living', 'Adult', 'Aged', 'Aged, 80 and over', 'Electromyography', 'Female', 'Frail Elderly', 'Humans', 'Male', 'Middle Aged'] | 26,880,179 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.405.255', 'E01.370.530.255'], ['M01.060.116.100.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Exposure of conjugative plasmid carrying Escherichia coli biofilms to male-specific bacteriophages. | Escherichia coli carrying a natural conjugative F-plasmid generates F-pili mating pairs, which is important for early biofilm formation. In this study, we investigated the effect of male-specific filamentous single stranded DNA bacteriophage (f1) and RNA bacteriophage (MS2) on the formation of biofilms by E. coli carry... | ['Biofilms', 'Coliphages', 'Conjugation, Genetic', 'Escherichia coli', 'Fimbriae, Bacterial', 'Microbial Interactions', 'Plasmids', 'RNA Phages'] | 20,962,879 | [['A20.593', 'G06.120'], ['B04.123.205'], ['G05.728.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.284.180.285', 'A20.843'], ['G06.550'], ['G05.360.600'], ['B04.123.691']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Experience in treating advanced prostate cancer with bladder outlet obstruction]. | BACKGROUND & OBJECTIVE: The incidence and discovery rate of prostate cancer is increased in recent years; with advanced age and multiple organs dysfunction, the advanced prostate cancer patients have poor quality of life. This study was to explore suitable treatment for these patients.METHODS: A total of 80 advanced pr... | ['Adenocarcinoma', 'Aged', 'Aged, 80 and over', 'Androgen Antagonists', 'Antigens, Neoplasm', 'Flutamide', 'Humans', 'Male', 'Orchiectomy', 'Prostatic Neoplasms', 'Transurethral Resection of Prostate', 'Urinary Bladder Neck Obstruction'] | 16,219,150 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D06.347.065', 'D27.505.696.399.450.065'], ['D23.050.285'], ['D02.065.199.420', 'D02.092.146.113.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'], ['C04.588.945.440.770', 'C12.29... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Finding any Waldo with zero-shot invariant and efficient visual search. | Searching for a target object in a cluttered scene constitutes a fundamental challenge in daily vision. Visual search must be selective enough to discriminate the target from distractors, invariant to changes in the appearance of the target, efficient to avoid exhaustive exploration of the image, and must generalize to... | ['Adult', 'Attention', 'Computer Simulation', 'Cues', 'Female', 'Humans', 'Male', 'Pattern Recognition, Visual', 'Psychophysics', 'Reaction Time', 'Time Factors', 'Vision, Ocular', 'Visual Perception', 'Young Adult'] | 30,213,937 | [['M01.060.116'], ['F02.830.104.214'], ['L01.224.160'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E01.370.685', 'F04.096.753'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['G01.910.857'], ['F02.830.816.964', 'G02.111.820.48... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Morphological and quantitative study of the Leydig cells of pigs fed with anabolic doses of clenbuterol. | The effects of clenbuterol administered at anabolic doses on the testicular interstitium were studied in 30 pigs allocated to three experimental groups. The diet of two groups was supplemented with clenbuterol (Clb) (1 ppm), but whereas in the Clb+ group the treatment was given until slaughter (treatment period: 3 mont... | ['Adrenergic beta-Agonists', 'Animals', 'Clenbuterol', 'Histocytochemistry', 'Leydig Cells', 'Male', 'Microscopy, Electron', 'Random Allocation', 'Swine'] | 11,883,895 | [['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['B01.050'], ['D02.033.100.291.231', 'D02.092.063.291.231'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['A05.360.444.849.513', 'A06.300.312.782.513', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Accurate gene-tree reconstruction by learning gene- and species-specific substitution rates across multiple complete genomes. | Comparative genomics provides a general methodology for discovering functional DNA elements and understanding their evolution. The availability of many related genomes enables more powerful analyses, but requires rigorous phylogenetic methods to resolve orthologous genes and regions. Here, we use 12 recently sequenced ... | ['Animals', 'Artificial Intelligence', 'Drosophila', 'Evolution, Molecular', 'Genes, Fungal', 'Genes, Insect', 'Genome', 'Genomics', 'Models, Genetic', 'Phylogeny', 'Sequence Alignment', 'Species Specificity', 'Synteny'] | 17,989,260 | [['B01.050'], ['G17.035.250', 'L01.224.050.375'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G05.360.340.024.340.340', 'G05.360.340.357.500'], ['G05.360.340'], ['H01.158.273.180.350', 'H01.158.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Reduction in myocardial ischemic/reperfusion injury and neutrophil accumulation after therapeutic administration of streptokinase. | The benefit of thrombolytic agents to reduce myocardial infarct size, improve left ventricular (LV) function, and prolong survival in human subjects is generally recognized, although the precise mechanism is poorly defined. This study was designed to evaluate the cardioprotective effects of streptokinase (SK) in rats, ... | ['Animals', 'Cell Aggregation', 'Coronary Disease', 'Coronary Vessels', 'Foot', 'Free Radical Scavengers', 'Glucuronidase', 'Hemodynamics', 'In Vitro Techniques', 'Inflammation', 'Male', 'Myocardial Reperfusion Injury', 'Neutrophils', 'Peroxidase', 'Plasminogen Activators', 'Rabbits', 'Rats', 'Rats, Inbred Strains', 'S... | 1,723,770 | [['B01.050'], ['G04.198.251'], ['C14.280.647.250', 'C14.907.585.250'], ['A07.015.114.269', 'A07.015.908.194'], ['A01.378.610.250'], ['D27.505.519.217.500'], ['D08.811.277.450.426'], ['G09.330.380'], ['E05.481'], ['C23.550.470'], ['C14.280.238.615', 'C14.280.647.625', 'C14.907.585.625', 'C14.907.725.600', 'C23.550.767.8... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mytilus galloprovincialis fast growing phenotypes under different restrictive feeding conditions: Fast feeders and energy savers. | The present study aims to test if the environmental conditions prevailing during the growing period can determine the physiological profiles of specimens differentiated as fast (F) or slow (S) growers in the mussel Mytilus galloprovincialis. We reared mussel spats in the laboratory under two different conditions. In Tr... | ['Animals', 'Diet', 'Environmental Monitoring', 'Feeding Behavior', 'Mytilus', 'Phenotype'] | 29,907,318 | [['B01.050'], ['G07.203.650.240'], ['N06.850.460.350.080', 'N06.850.780.375'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.500.644.080.537.500'], ['G05.695']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pyocyanina contributory factor in haem acquisition and virulence enhancement of Porphyromonas gingivalis in the lung [corrected]. | Several recent studies show that the lungs infected with Pseudomonas aeruginosa are often co-colonised by oral bacteria including black-pigmenting anaerobic (BPA) Porphyromonas species. The BPAs have an absolute haem requirement and their presence in the infected lung indicates that sufficient haem, a virulence up-regu... | ['Animals', 'Heme', 'Leukocyte Elastase', 'Lung', 'Mice', 'Mice, Inbred C57BL', 'Oxidation-Reduction', 'Oxyhemoglobins', 'Porphyromonas gingivalis', 'Pyocyanine', 'Virulence'] | 25,706,529 | [['B01.050'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D08.811.277.656.300.760.560.500', 'D08.811.277.656.959.350.560.500'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A poly(å-caprolactone) device for sustained release of an anti-glaucoma drug. | Implantable dorzolamide-loaded discs were prepared by blending poly(å-caprolactone), PCL, with poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), Lu. By blending, crystallinity, water uptake and mass loss were modified relative to the pure polymers. Burst was diminished by coating the discs with a PCL... | ['Animals', 'Antihypertensive Agents', 'Biocompatible Materials', 'Calorimetry, Differential Scanning', 'Cornea', 'Delayed-Action Preparations', 'Diffusion', 'Drug Delivery Systems', 'Glaucoma', 'Polyesters', 'Polymers', 'Porosity', 'Rabbits', 'Regression Analysis', 'Sulfonamides', 'Tetrazolium Salts', 'Thiazoles', 'Th... | 21,293,056 | [['B01.050'], ['D27.505.954.411.162'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E05.196.131.310', 'E05.196.370.310'], ['A09.371.060.217'], ['D26.255.210', 'E02.319.300.253'], ['G01.202', 'G02.196'], ['E02.319.300'], ['C11.525.381'], ['D05.750.728', 'D25.720.728', 'J01.637.051.720.728'], ['D05.750', 'D25.720... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Cytopathic and non-cytopathic biotypes of border disease virus induce polypeptides of different molecular weight with common antigenic determinants. | Ten monoclonal antibodies have been raised against lysates of cells infected with cytopathic border disease virus (BDV). These antibodies all recognize non-cytopathic BDV and react with a number of different strains of bovine viral diarrhoea virus (BVDV). Studies with radiolabelled cell lysates show that all the antibo... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, Viral', 'Border Disease', 'Cells, Cultured', 'Epitopes', 'Fluorescent Antibody Technique', 'Immunoblotting', 'Mice', 'Molecular Weight', 'Pestivirus', 'Viral Proteins'] | 1,693,167 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.327'], ['C01.925.782.350.675.100', 'C22.836.160'], ['A11.251'], ['D23.050.550'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The oro-cervical lesions in patients with malignant hemopathy at the National Hospital at Donka-Conakry]. | The oro-cervical lesions observed during the malignant hemopathy can take various aspects and several tissues like the mouth, salivary glands, and bones of the face may be involved. The objectives of this study were to assess the status of the oral and cervical regions in patients with malignant hemopathy and to descri... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Hematologic Neoplasms', 'Hospitals', 'Humans', 'Lymphatic Diseases', 'Male', 'Mouth Diseases', 'Neck', 'Prospective Studies', 'Young Adult'] | 19,666,360 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C04.588.448', 'C15.378.400'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604'], ['C07.465'], ['A01.598'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['M01.060.116.815']... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Intra-aortic balloon pumping: theory and practice. Experience with 325 patients. | Intra-aortic balloon pumping to support the failing circulation is now an accepted therapeutic modality. The device is simple. Insertion can be accomplished rapidly and efficiently in emergency rooms, coronary care units, cardiac catheterization suites and operating rooms, preoperatively, intraoperatively and postopera... | ['Adult', 'Aged', 'Assisted Circulation', 'Female', 'Hemodynamics', 'Humans', 'Intra-Aortic Balloon Pumping', 'Male', 'Middle Aged'] | 708,286 | [['M01.060.116'], ['M01.060.116.100'], ['E04.050'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.050.215.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Disc spaces, vertebral dimensions, and angle values at the lumbar region: a radioanatomical perspective in spines with L5-S1 transitions: clinical article. | OBJECT: Low-back pain (LBP) has been associated with lumbar spines of normal morphology as well as those with L5-S1 "transitional" vertebrae. It is hard to find literature that quantifies the overall morphological changes in lumbar spines as related to transitional states. The object of this study was to investigate lu... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Intervertebral Disc', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Radiography', 'Retrospective Studies', 'Sacrum'] | 21,740,126 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E01.370.350.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Case report: Acute Intermittent Porphyria in a 21 year-old active duty male. | Acute Intermittent Porphyria (AIP) is one of a group of rare metabolic disorders arising from reduced activity of any of the enzymes in the heme biosynthetic pathway. The porphyrias can be very difficult for the practitioner to understand. There are several types of porphyrias, which have been known by various differen... | ['Humans', 'Male', 'Military Personnel', 'Porphyria, Acute Intermittent', 'Young Adult'] | 21,706,462 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['C06.552.830.150', 'C16.320.850.742.150', 'C17.800.827.742.150', 'C18.452.811.400.150'], ['M01.060.116.815']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Disease patterns of juvenile dermatomyositis from Western India. | A retrospective assessment of clinical characteristics, complications/ associations, laboratory investigations, treatment modalities and outcome in an inceptional cohort of 22 (male-13) children with juvenile dermatomyositis (JDM) receiving treatment at Jaslok Hospital, Mumbai during 1997- 2012 was performed . Mean age... | ['Adolescent', 'Child', 'Child, Preschool', 'Dermatomyositis', 'Female', 'Humans', 'India', 'Male', 'Retrospective Studies', 'Steroids', 'Treatment Outcome'] | 23,798,628 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Need for eye and vision care in an underserved population: refractive errors and other ocular anomalies in the Sioux. | The Native American population has a significant unmet need for eye and vision care. Beginning with the onset of continuous eye care on two reservations in North and South Dakota, a compilation was done of refractive errors and other clinical findings in 1886 Sioux Indians. The results are similar to previous findings ... | ['Adolescent', 'Adult', 'Age Factors', 'Child', 'Child, Preschool', 'Delivery of Health Care', 'Eye', 'Eye Diseases', 'Female', 'Health Services', 'Humans', 'Indians, North American', 'Infant', 'Infant, Newborn', 'Male', 'Medically Underserved Area', 'Middle Aged', 'Refractive Errors', 'Vision, Ocular', 'Visual Acuity'... | 3,740,210 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['N04.590.374', 'N05.300'], ['A01.456.505.420', 'A09.371'], ['C11'], ['N02.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['M01.060.703'], ['M01.060.703.520'], ['N03.349.650... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bacillus subtilis division protein DivIVA - screen for stable oligomer state conditions. | The cell division protein DivIVA is predicted to be a coiled-coil, tropomyosin-like protein, that self-associates both in vivo and in vitro into oligomers of up to 10-12 monomers. A simple and quick screen for conditions supporting the stable oligomer structure has been developed revealing that DivIVA forms a homogeneo... | ['Bacillus subtilis', 'Bacterial Proteins', 'Cell Cycle Proteins', 'Crystallization', 'Electrophoresis, Polyacrylamide Gel', 'Protein Structure, Quaternary', 'Recombinant Proteins'] | 12,351,857 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['D12.776.167'], ['E05.196.300', 'G02.171'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.111.570.820.709.550'], ['D12.776.828']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Responding to trainee doctors in difficulty. | Appropriate workload, good clinical and educational supervision and rigorous appraisal routines will prevent a number of trainees developing difficulties. When difficulties do occur the presence of such arrangements will facilitate appropriate emotional and practical handling of these problems. | ['Defense Mechanisms', 'Education, Medical, Graduate', 'Employee Discipline', 'Employee Performance Appraisal', 'Humans', 'Medical Staff, Hospital', 'Physician Impairment', 'State Medicine', 'United Kingdom'] | 10,953,743 | [['F01.393'], ['I02.358.337.350', 'I02.358.399.350'], ['N04.452.677.358'], ['N04.452.677.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.630.490', 'M01.526.485.740.422', 'N02.360.630.490', 'N02.360.740.422'], ['I01.880.604.583.524.528.500', 'N03.706.535.606.528.500'], ['N03.349.550.902', 'N03.858'... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Relationship between obesity's adverse health risk and body mass index in African-American women. | Overweight and obesity are major threats to public health in the United States, affecting more than 60% of the adult population. African-American women are disproportionately represented in the largest increases of overweight and obese Americans, and they are at greater risk for poor health and obesity's related disord... | ['Adult', 'African Continental Ancestry Group', 'Aged', 'Analysis of Variance', 'Body Mass Index', 'Chi-Square Distribution', 'Health Status', 'Humans', 'Middle Aged', 'Obesity', 'Risk Assessment', 'United States'] | 19,397,051 | [['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['I01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Genomic characterization, kinetics, and pathways of sulfamethazine biodegradation by Paenarthrobacter sp. A01. | Biodegradation is an important route for the removal of sulfamethazine (SMZ), one of the most commonly used sulfonamide antibiotics, in the environment. However, little information is known about the kinetics, products, and pathways of SMZ biodegradation owing to the complexity of its enzyme-based biotransformation pro... | ['Anti-Bacterial Agents', 'Biodegradation, Environmental', 'Genome, Bacterial', 'Kinetics', 'Micrococcaceae', 'Sewage', 'Sulfamethazine', 'Water Pollutants, Chemical'] | 31,330,364 | [['D27.505.954.122.085'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G05.360.340.358.207'], ['G01.374.661', 'G02.111.490'], ['B03.510.024.850', 'B03.510.400.500'], ['D20.944.932.500'], ['D02.065.884.725.862', 'D02.092.146.807.862', 'D02.886.590.700.725.862'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Aqueous injection of quercetin: An approach for confirmation of its direct in vivo cardiovascular effects. | Potential positive effects of flavonol quercetin on humans were suggested by many studies. However, it is not clear if these effects are mediated by quercetin or its metabolites. The in vivo confirmation of quercetin effects is largely hindered by its low water solubility and thus impossibility to test directly its imp... | ['Animals', 'Antihypertensive Agents', 'Biological Availability', 'Blood Pressure', 'Chemistry, Pharmaceutical', 'Disease Models, Animal', 'Drug Compounding', 'Humans', 'Hypertension', 'Injections, Intravenous', 'Male', 'Particle Size', 'Povidone', 'Quercetin', 'Rats', 'Rats, Inbred SHR', 'Rats, Wistar', 'Solubility', ... | 29,474,897 | [['B01.050'], ['D27.505.954.411.162'], ['G03.787.151', 'G07.690.725.129'], ['E01.370.600.875.249', 'G09.330.380.076'], ['H01.158.703.007', 'H01.181.466'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.916.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E02.319.267.082.750', 'E02.319.26... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Cannulation of the ascending aorta for cardiopulmonary bypass. Experience with 9,000 cases. | The Cleveland Clinic team has now accumulated experience with cannulation of the ascending aorta for arterial return in more than 9,000 patients. Since adoption of this technique, only one lethal dissection has occurred and other related complications have been minimal. Technique, surgical pitfalls, contraindications, ... | ['Aorta', 'Aortic Aneurysm', 'Cardiopulmonary Bypass', 'Catheterization', 'Extracorporeal Circulation', 'Humans'] | 1,246,151 | [['A07.015.114.056'], ['C14.907.055.239', 'C14.907.109.139'], ['E04.292.413'], ['E02.148', 'E05.157'], ['E04.292'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of TVE application during 70% hepatectomy on regeneration capacity of rats. | BACKGROUND: For adequate control of excess bleeding during liver resection, total vascular exclusion (TVE) is preferred by surgeons, especially when the tumor is located in the posterior liver lobes or near the cava. To the authors' knowledge, the effects of TVE technique on the postoperative liver regeneration process... | ['Animals', 'Constriction', 'Hepatectomy', 'Hepatic Artery', 'Hepatic Veins', 'Ischemia', 'Liver', 'Liver Regeneration', 'Male', 'Models, Animal', 'Necrosis', 'Oxidative Stress', 'Portal Vein', 'Rats', 'Rats, Wistar', 'Vascular Surgical Procedures'] | 15,734,492 | [['B01.050'], ['E05.225'], ['E04.210.556'], ['A07.015.114.407'], ['A07.015.908.380'], ['C23.550.513'], ['A03.620'], ['G10.261.475', 'G16.762.468'], ['E05.598'], ['C23.550.717'], ['G03.673', 'G07.775.750'], ['A07.015.908.670.567'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.90... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does the clinical evaluation of the cardiac status predict outcome in patients with abdominal aortic aneurysms? | A cost-effective method to reduce mortality rates after abdominal aortic aneurysm repair centers on selecting and investigating only those patients at risk for cardiac-related death. All 146 patients undergoing asymptomatic abdominal aortic aneurysm repair over a 5-year period (1986 to 1990) were retrospectively placed... | ['Aged', 'Aorta, Abdominal', 'Aortic Aneurysm', 'Coronary Disease', 'Female', 'Heart Diseases', 'Heart Failure', 'Humans', 'Male', 'Predictive Value of Tests', 'Retrospective Studies', 'Risk Factors', 'Tachycardia', 'Treatment Outcome'] | 1,597,894 | [['M01.060.116.100'], ['A07.015.114.056.205'], ['C14.907.055.239', 'C14.907.109.139'], ['C14.280.647.250', 'C14.907.585.250'], ['C14.280'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.500.500', 'E05.31... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Voluminous nodular splenomegaly in Gaucher disease: a case report]. | Patients affected by type 1 Gaucher disease (an autosomal recessive inheritance lysosome storage disorder) develop nodular splenomegaly in 20 to 30% of cases where imiglucerase therapy proves ineffective. The lack of response to imiglucerase therapy on spleen nodules could be an indication of the existence or developme... | ['Gaucher Disease', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Spleen', 'Splenomegaly'] | 19,375,198 | [['C10.228.140.163.100.435.825.400', 'C16.320.565.189.435.825.400', 'C16.320.565.398.641.803.441', 'C16.320.565.595.554.825.400', 'C18.452.132.100.435.825.400', 'C18.452.584.687.803.441', 'C18.452.648.189.435.825.400', 'C18.452.648.398.641.803.441', 'C18.452.648.595.554.825.400'], ['B01.050.150.900.649.313.988.400.112.... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Associations Among Mucosal and Transmural Healing and Fecal Level of Calprotectin in Children With Crohn's Disease. | BACKGROUND & AIMS: Bowel healing is an important goal of therapy for patients with Crohn's disease (CD). Although there have been many studies of mucosal healing, transmural healing (ie, in the bowel wall) has not been investigated in children. We analyzed data from the ImageKids study to determine associations among m... | ['Adolescent', 'Blood Chemical Analysis', 'C-Reactive Protein', 'Child', 'Crohn Disease', 'Drug Monitoring', 'Endoscopy, Gastrointestinal', 'Feces', 'Female', 'Humans', 'Intestines', 'Leukocyte L1 Antigen Complex', 'Magnetic Resonance Imaging', 'Male', 'Prospective Studies', 'Sensitivity and Specificity'] | 29,501,599 | [['M01.060.057'], ['E01.370.225.124.100', 'E05.200.124.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['M01.060.406'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E01.370.520.200'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['A12.459']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The brain and its main anatomical subdivisions in living hominoids using magnetic resonance imaging. | Primary comparative data on the hominoid brain are scarce and major neuroanatomical differences between humans and apes have not yet been described satisfactorily, even at the gross level. Basic questions that involve the evolution of the human brain cannot be addressed adequately unless the brains of all extant homino... | ['Animals', 'Brain Mapping', 'Gorilla gorilla', 'Hominidae', 'Humans', 'Hylobates', 'Magnetic Resonance Imaging', 'Pan paniscus', 'Pan troglodytes', 'Pongo pygmaeus'] | 10,656,781 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.375'], ['B01.050.150.900.649.313.988.400.112.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.420.390'], ['E01.370.350.825.500'], ['B01.050.150.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Minilaparoscopic (needlescopic) cholecystectomy: a study of 1,011 cases. | BACKGROUND: The safety and feasibility of minilaparoscopic cholecystectomy has not been documented with a large patient sample. This study reports the results of 1,011 minilaparoscopic cholecystectomies performed in a single institution.METHODS: From November 1997 to May 2002, 1,023 consecutive patients underwent minil... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cholecystectomy, Laparoscopic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Needles', 'Postoperative Complications'] | 15,791,373 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.612'], ['C23.550.767']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effect of the brain 5-HT2 receptor blockade on gastric mucosa damage caused by social stress in males of two mouse strains]. | Mice-losers in social conflicts had an increased number of haemorrhages and erosions in gastric mucosa as compared with the control and winners-mice. Administration of ciproheptadine and/or ketanserin enhanced the neurogenic gastric damage both in the winners and in control mice. The CBA strain mice were more sensitive... | ['Animals', 'Conflict, Psychological', 'Cyproheptadine', 'Gastric Mucosa', 'Gastrointestinal Hemorrhage', 'Ketanserin', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Receptors, Serotonin', 'Serotonin Antagonists', 'Species Specificity', 'Stress, Psychological'] | 10,643,606 | [['B01.050'], ['F01.658.209'], ['D02.455.426.559.847.181.384.340', 'D03.383.621.160', 'D04.615.181.384.340'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C06.405.227', 'C23.550.414.788'], ['D03.383.621.365', 'D03.633.100.786.830.333'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effects of supplementation with branched-chain amino acids on protein-nutritional status in rats treated by carbon tetrachloride]. | A study was conducted to investigate effects of oral supplementation with branched-chain amino acids (BCAA) on protein-nutritional status in rats with liver cirrhosis. Liver cirrhosis was induced in male strain Sprague-Dawley rats by simultaneously administrating carbon tetrachloride (500 mg/kg, twice a week, intracuta... | ['Amino Acids, Branched-Chain', 'Animals', 'Carbon Tetrachloride Poisoning', 'Food, Fortified', 'Liver Cirrhosis, Experimental', 'Male', 'Nutritional Status', 'Proteins', 'Rats'] | 2,585,790 | [['D12.125.070'], ['B01.050'], ['C25.723.177'], ['G07.203.300.515', 'J02.500.515'], ['C06.552.630.467', 'C23.550.355.412.467', 'E05.598.500.468'], ['G07.203.650.650', 'N01.224.425.525'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Report by the Scientific Working Group for Therapy of Lung Diseases: German Fibrosis Register with initial results]. | The aim of this study was to evaluate the occurrence of interstitial lung diseases (ILD) in Germany. Therefore members of the WATL developed a questionnaire which was sent to pulmonary and other physicians who may encounter patients with ILD. In 1995 altogether 234 patients (105 males, 129 females, mean age 51 years, m... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Cross-Sectional Studies', 'Female', 'Germany', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Occupational Diseases', 'Pulmonary Fibrosis', 'Registries'] | 9,091,884 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Clinical analysis of heterozygous ABCA3 mutations in children]. | OBJECTIVE: To investigate the association of ATP-binding cassette transporter A3 (ABCA3) gene mutations with severe neonatal respiratory distress syndrome (NRDS) and lung disease in children.METHOD: Thirty-eight children hospitalized with respiratory disorders in Children's Hospital of Chongqing Medical University from... | ['ATP-Binding Cassette Transporters', 'Adolescent', 'Child', 'Child, Preschool', 'DNA Mutational Analysis', 'Exons', 'Female', 'Heterozygote', 'Humans', 'Infant', 'Infant, Newborn', 'Lung', 'Lung Diseases, Interstitial', 'Male', 'Mutation', 'Radiography', 'Respiratory Distress Syndrome, Newborn'] | 24,915,907 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.393.760.700.300'], ['G05.360.340.024.340.137.232'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A04.41... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Design and characterization of a laser-based instrument with spectroscopic feedback control for treatment of vascular lesions: the "Smart Scalpel". | To improve the effectiveness of microsurgical techniques, we are developing a semi-autonomous robotic surgical tool (called the "Smart Scalpel") as an alternate approach to treatment of vascular lesions. The device employs optical reflectance spectroscopy as part of a line scan imaging system to identify and selectivel... | ['Animals', 'Blood Flow Velocity', 'Equipment Design', 'Lasers', 'Mice', 'Microsurgery', 'Monitoring, Intraoperative', 'Reproducibility of Results', 'Spectrum Analysis', 'Telangiectasis', 'Vascular Surgical Procedures'] | 11,092,425 | [['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E05.320'], ['E07.632.490', 'E07.710.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['E04.494', 'E05.591.580'], ['E01.370.520.510', 'E04.510'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.196.867'], ['C14.907.823... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Protein expression of the tumor suppressors p16INK4A and p53 and disease progression in recurrent respiratory papillomatosis. | BACKGROUND: Recurrent respiratory papillomatosis (RRP) is a benign condition that rarely metastasizes as invasive squamous cell carcinoma. Although this disease is associated with human papillomavirus, the role of this virus in tumorigenesis is unclear.OBJECTIVES: The aim of this study is to assess the involvement of t... | ['Adolescent', 'Adult', 'Biopsy', 'Carcinoma in Situ', 'Carcinoma, Squamous Cell', 'Cell Nucleus', 'Cell Transformation, Neoplastic', 'Child', 'Cyclin-Dependent Kinase Inhibitor p16', 'Disease Progression', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunohistochemistry', 'Laryngeal Neoplasms', 'Mal... | 17,277,618 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.240'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['C04.697.098.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Expression of HSP70 mRNA and MDR1 mRNA in K562 cells induced by heat shock and ADM]. | This study was purpose to investigate the expression levels of HSP70 and MDR1 genes under heat shock and/or adriamycin (ADM) chemotherapy stimulation. The K562 cells were bathed in water at 43 degrees C for 1 hour, then the heat-treated K562 cells were collected and were cultured at 37 degrees C. The expression of HSP7... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Antibiotics, Antineoplastic', 'Cell Proliferation', 'Doxorubicin', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Response', 'Humans', 'K562 Cells', 'RNA, Messenger'] | 18,088,459 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D27.505.954.248.106'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.455.426.559.847.562.050.200.175', 'D... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure and genomic organization of immunoglobulin light chain in the channel catfish. An unusual genomic organizational pattern of segmental genes. | Channel catfish L chain cDNA was obtained through a PCR strategy and used to isolate multiple L chain clones from cDNA and genomic libraries. Sequence analysis of full-length cDNA indicates that the V region is preceded by a leader peptide, and represented by framework and CDR regions. Both VL and CL domains contain th... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'DNA, Complementary', 'Genes, Immunoglobulin', 'Humans', 'Ictaluridae', 'Immunoglobulin Light Chains', 'Molecular Sequence Data', 'Sequence Homology, Amino Acid', 'Sequence Homology, Nucleic Acid', 'Species Specificity', 'Transcription, Genetic',... | 8,258,698 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.360.340.024.340.335', 'G12.500.299'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Urinary N-acetyl-beta-glucosaminidase excretion is a marker of tubular cell dysfunction and a predictor of outcome in primary glomerulonephritis. | BACKGROUND: The urinary excretion of N-acetyl-beta-glucosamynidase (NAG) is increased in subjects exposed to substances toxic for renal tubular cells. In experimental and human glomerular diseases, its increased excretion is probably due to the dysfunction of tubular epithelial cells induced by increased traffic of pro... | ['Acetylglucosaminidase', 'Adult', 'Biomarkers', 'Female', 'Glomerulonephritis', 'Glomerulonephritis, Membranoproliferative', 'Glomerulosclerosis, Focal Segmental', 'Humans', 'Kidney', 'Kidney Tubules', 'Male', 'Middle Aged', 'Nephrosis, Lipoid', 'Nephrotic Syndrome', 'Prognosis', 'Proteinuria', 'Reference Values'] | 12,401,843 | [['D08.811.277.450.483.180.500'], ['M01.060.116'], ['D23.101'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['C12.777.419.570.363.615', 'C13.351.968.419.570.363.615', 'C20.425'], ['C12.777.419.570.363.660', 'C13.351.968.419.570.363.640'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['A05.8... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Embedding and publishing interactive, 3-dimensional, scientific figures in Portable Document Format (PDF) files. | With the latest release of the S2PLOT graphics library, embedding interactive, 3-dimensional (3-d) scientific figures in Adobe Portable Document Format (PDF) files is simple, and can be accomplished without commercial software. In this paper, we motivate the need for embedding 3-d figures in scholarly articles. We expl... | ['Imaging, Three-Dimensional', 'Programming Languages', 'Publishing', 'Software'] | 24,086,243 | [['E01.370.350.400', 'L01.224.308.410'], ['L01.224.900.780'], ['L01.737'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Removal of added nitrate in the single, binary, and ternary systems of cotton burr compost, zerovalent iron, and sediment: Implications for groundwater nitrate remediation using permeable reactive barriers. | Recent research has shown that carbonaceous solid materials and zerovalent iron (Fe(0)) may potentially be used as media in permeable reactive barriers (PRBs) to degrade groundwater nitrate via heterotrophic denitrification in the solid carbon system, and via abiotic reduction and autotrophic denitrification in the Fe(... | ['Biodegradation, Environmental', 'Geologic Sediments', 'Gossypium', 'Iron', 'Nitrates', 'Oxidation-Reduction', 'Soil', 'Water Pollutants, Chemical'] | 17,257,645 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['G01.311.330', 'G16.500.320'], ['B01.650.940.800.575.912.250.859.821.500.244'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['G02.700', 'G03.295.531'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Resistant hypertension. | UNLABELLED: A 53 year old woman with hypercholesterolemia treated with statins, with no history of cardiovascular disease, was referred to the Hypertension and Vascular Risk Unit for management of hypertension resistant to 4 antihypertensive agents at full doses. The patient had obesity, with a body mass index of 36.3k... | ['Antihypertensive Agents', 'Diuretics', 'Drug Resistance', 'Female', 'Humans', 'Hypertension', 'Middle Aged', 'Spironolactone'] | 23,827,205 | [['D27.505.954.411.162'], ['D27.505.696.560.500'], ['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['D02.540.679', 'D04.210.500.745.745.855']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Expression of caspase-3 mRNA in the hippocampus of seven-day-old hypoxic-ischemic rats and the mechanism of neural protection with magnesium sulfate]. | OBJECTIVE: There was consanguineous relationship between caspase-3 and early damage after hypoxia and ischemia. Caspase-3 plays a key role in the process of apoptosis in neuron. Magnesium sulfate could protect neuron from injuries, but the mechanism was not clear. The study was to investigate the expression of caspase-... | ['Animals', 'Animals, Newborn', 'Caspase 3', 'Caspases', 'Female', 'Gene Expression Regulation, Enzymologic', 'Hippocampus', 'Hypoxia-Ischemia, Brain', 'Magnesium Sulfate', 'Male', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Reverse Transcriptase Polymerase Chain Reaction'] | 14,756,962 | [['B01.050'], ['B01.050.050.282'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G05.308.320'], ['A08.186.211.18... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outbreak of trichinellosis caused by Trichinella papuae, Thailand, 2006. | In 2006, the Thailand Ministry of Public Health studied 28 patients from a village in northern Thailand. All had myalgia, edema, fever, and gastrointestinal symptoms; most had eaten wild boar. A muscle biopsy specimen from a patient showed nonencapsulated larvae with a cytochrome oxidase I gene sequence of Trichinella ... | ['Adolescent', 'Adult', 'Animals', 'Antibodies, Helminth', 'Disease Outbreaks', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Species Specificity', 'Sus scrofa', 'Swine', 'Swine Diseases', 'Thailand', 'Trichinella', 'Trichinellosis', 'Young Adult'] | 19,046,519 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.393.620.500'], ['G16.824'], ['B01.050.150.900.649.313.500.880.399'], ['B01.050.150.9... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cranial neuropathy as a presenting sign of recurrent aggressive skin cancer. | OBJECTIVE: The purpose of this study was to identify and characterize recurrent skin cancers of the head and neck presenting with cranial neuropathies and to review the presentation and the management for this rare subset of cutaneous neoplasms.MATERIALS AND METHODS: A retrospective review was performed for all patient... | ['Aged', 'Carcinoma, Squamous Cell', 'Cohort Studies', 'Cranial Nerve Diseases', 'Head and Neck Neoplasms', 'Humans', 'Melanoma', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Retrospective Studies', 'Skin Neoplasms', 'Survival Rate'] | 18,248,467 | [['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C10.292'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['M01.060.116.630... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Criteria of the classification of spondylarthropathies]. | A system of classification criteria of spondyloarthropathies was experimented in three studies. They have permitted to measure its specificity which is 86.6 p. cent and its sensitivity which is 90 p. cent. This system permits to compare theory and clinical practice and also to classify disease not yet classified. The p... | ['Arthritis', 'Europe', 'France', 'Humans', 'Multicenter Studies as Topic', 'New York', 'Prospective Studies', 'Retrospective Studies', 'Spondylitis'] | 2,181,618 | [['C05.550.114'], ['Z01.542'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.658', 'N05.715.360.330.643', 'N06.850.520.450.643'], ['Z01.107.567.875.075.437', 'Z01.107.567.875.350.530', 'Z01.107.567.875.500.530'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.4... | ['Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosis. | G protein-coupled receptors (GPCRs) are integral to cellular function in nearly all physiologic and many pathologic processes. GPCR signaling represents an intricate balance between receptor activation, inactivation (desensitization, internalization and degradation) and resensitization (recycling and de novo synthesis)... | ['Adaptor Protein Complex 2', 'Apoptosis', 'Arrestins', 'Blotting, Western', 'Endosomes', 'Green Fluorescent Proteins', 'Humans', 'Immunoprecipitation', 'Microscopy, Fluorescence', 'Protein Binding', 'Protein Transport', 'Receptors, Formyl Peptide', 'Receptors, G-Protein-Coupled', 'Transfection', 'U937 Cells'] | 19,602,204 | [['D12.776.543.990.150.200'], ['G04.146.954.035'], ['D12.644.360.024.098', 'D12.776.157.057.005', 'D12.776.306.090', 'D12.776.476.024.104', 'D12.776.543.090'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.430.214.190.875.190.880.337'], ['D12.776.532.265'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thickness of cementum/dentin in mesial roots of mandibular first molars. | The mesial roots of 15 human first lower molars, along with the corresponding half of the tooth crown, were studied to determine the thickness of dentin-cementum. A device was developed whereby these could be embedded in resin with a precisely known orientation in space. The roots were radiographed in mesiodistal and v... | ['Densitometry', 'Dental Cementum', 'Dentin', 'Humans', 'Mandible', 'Molar', 'Odontometry', 'Reference Values', 'Tooth Root'] | 1,298,791 | [['E05.196.712.224'], ['A14.549.167.646.267', 'A14.549.167.900.250'], ['A14.549.167.900.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['A14.549.167.860.525'], ['E01.370.600.024.650', 'E05.041.650', 'E06.623'], ['E05.978.810'], ['A14.549.167.900.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A rare case of squamous cell carcinoma of the lung harbouring ALK and BRAF activating mutations. | The management of non-small cell lung cancer has significantly changed over the past few years through greater understanding of tumour biology. The identification of activating mutations has led to the development of targeted agents. Coexisting mutations in non-small cell lung cancer is uncommon, particularly in squamo... | ['Aged', 'Anaplastic Lymphoma Kinase', 'Carcinoma, Non-Small-Cell Lung', 'Carcinoma, Squamous Cell', 'Humans', 'Male', 'Mutation', 'Proto-Oncogene Proteins B-raf', 'Receptor Protein-Tyrosine Kinases', 'Transcriptional Activation'] | 23,499,398 | [['M01.060.116.100'], ['D08.811.913.696.620.682.725.400.002', 'D12.776.543.750.630.002'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['D08.811.913.696.620.682.700... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
pH effects on basolateral membrane ion conductances in gallbladder epithelium. | The pH sensitivity of the basolateral membrane voltage of Necturus gallbladder epithelial cells (Vcs) was evaluated with conventional and pH-sensitive intracellular microelectrodes. Elevating solution CO2 from 1 to 5% (at constant [HCO3-] = 10 mM) caused a depolarization of Vcs from -76 +/- 3 to -60 +/- 2 mV and a decr... | ['Animals', 'Bicarbonates', 'Cell Membrane', 'Chlorides', 'Electric Conductivity', 'Epithelium', 'Gallbladder', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Ion Channels', 'Kinetics', 'Mathematics', 'Models, Theoretical', 'Necturus', 'Potassium'] | 2,472,068 | [['B01.050'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['A11.284.149'], ['D01.210.450.150', 'D01.248.497.158.215'], ['G01.358.500.249.277'], ['A10.272'], ['A03.159.439'], ['G02.300'], ['E05.481'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['G01.374.661', 'G02.111.490'], ['H01.548... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonsurgical removal of foreign body from right heart. A new percutaneous approach. | A new method is described for the nonsurgical removal of foreign bodies from the right heart. By means of the percutaneous Seldinger Technique, endoscopic forceps were passed throught the internal jugular vein to remove a fragment of polyvinyl catheter from the right atrium of a patient who had had heart surgery. The p... | ['Cardiac Catheterization', 'Female', 'Foreign Bodies', 'Heart', 'Humans', 'Middle Aged'] | 1,263,563 | [['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['C26.392'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein. | Melatonin plays an important role in regulating circadian rhythms. It also acts as a potent antioxidant and regulates glucose and lipid metabolism, although the exact action mechanism is not clear. The á2-HS-glycoprotein gene (AHSG) and its protein, fetuin-A (FETUA), are one of the hepatokines and are known to be assoc... | ['Animals', 'Dietary Fats', 'Endoplasmic Reticulum Stress', 'Fatty Liver', 'Hep G2 Cells', 'Humans', 'Insulin Resistance', 'Melatonin', 'Mice', 'Palmitic Acid', 'alpha-2-HS-Glycoprotein'] | 29,607,540 | [['B01.050'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G04.434'], ['C06.552.241'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['D03.633.100.473.914.481', 'D06.472.506'], ['B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Susceptibility of melanized and nonmelanized Cryptococcus neoformans to the melanin-binding compounds trifluoperazine and chloroquine. | Cryptococcus neoformans is an opportunistic fungal pathogen which becomes heavily melanized in the presence of phenolic substrates such as L-dopa. Various drugs are known to bind to melanin with high affinity, including the antipsychotic agent trifluoperazine and the antimalarial agent chloroquine. We hypothesized that... | ['Chloroquine', 'Cryptococcus neoformans', 'DNA, Fungal', 'Dopamine Agents', 'Dopamine Antagonists', 'Flow Cytometry', 'Levodopa', 'Melanins', 'Microbial Sensitivity Tests', 'Trifluoperazine'] | 8,851,567 | [['D03.633.100.810.050.180'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['D13.444.308.300'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of nonanimal high- and low-molecular-mass chondroitin sulfates produced by a biotechnological process in an animal model of polyarthritis. | BACKGROUND/AIMS: We planned to report on the effect of two nonanimal chondroitin sulfates (CSs) with different molecular masses produced using an innovative biotechnological process in an adjuvant arthritis animal model.METHODS: The experiments included healthy animals, untreated arthritic animals and arthritic animals... | ['Animals', 'Anti-Inflammatory Agents', 'Arthritis', 'C-Reactive Protein', 'Chondroitin Sulfates', 'Disease Models, Animal', 'Interleukin-1beta', 'Interleukin-6', 'Male', 'Rats, Inbred Lew', 'Tarsal Joints', 'gamma-Glutamyltransferase'] | 25,247,259 | [['B01.050'], ['D27.505.954.158'], ['C05.550.114'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D09.698.373.200.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.374.500.400.600', 'D23... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Design and characterization of bivalent compounds as potential neuroprotectants for Alzheimer's disease: Impact of the spacer on biological activity. | In our continuing efforts to develop bivalent compounds as potential neuroprotectants for Alzheimer's disease, a series of bivalent compounds that contain cholesterylamine and an extended spacer were synthesized and biologically characterized. Our results demonstrated that incorporation of a piperazine ring into the sp... | ['Alzheimer Disease', 'Dose-Response Relationship, Drug', 'Drug Design', 'Humans', 'Molecular Structure', 'Neuroprotective Agents', 'Piperazine', 'Piperazines', 'Structure-Activity Relationship'] | 29,475,586 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['D03.383.606.768'], ['D... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient synthetic access to the hetisine C20-diterpenoid alkaloids. A concise synthesis of nominine via oxidoisoquinolinium-1,3-dipolar and dienamine-Diels-Alder cycloadditions. | A concise synthetic approach to the hetisine C20-diterpenoid alkaloids is reported. The total synthesis of (+/-)-nominine was accomplished in a 15-step sequence employing a dual cycloaddition strategy. Key features of the synthesis include a reversible intramolecular 4-oxidoisoquinolinium betaine dipolar cycloaddition ... | ['Aconitum', 'Alkaloids', 'Amines', 'Crystallography, X-Ray', 'Cyclization', 'Diterpenes', 'Indoles', 'Isoquinolines', 'Models, Molecular', 'Molecular Structure', 'Stereoisomerism'] | 16,819,859 | [['B01.650.940.800.575.912.250.836.750.022'], ['D03.132'], ['D02.092'], ['E05.196.309.742.225'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['D02.455.849.291'], ['D03.633.100.473'], ['D03.633.100.531'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G02.607.445.682']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Apolipoprotein E genotype and risk for development of cataract and age-related macular degeneration. | PURPOSE: To study whether apolipoprotein E (APOE) genotypes are associated with risk for developing cataract and age-related macular degeneration (AMD).METHODS: A sample of 88 healthy adults (50-75 years) genotyped for polymorphisms of APOE underwent an eye examination which included visual acuity (VA) testing, slit-la... | ['Aged', 'Aging', 'Apolipoprotein E2', 'Apolipoprotein E3', 'Apolipoprotein E4', 'Apolipoproteins E', 'Cataract', 'Female', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Macular Degeneration', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Risk Factors'] | 18,498,549 | [['M01.060.116.100'], ['G07.345.124'], ['D10.532.091.500.249', 'D12.776.070.400.500.249', 'D12.776.521.120.500.249'], ['D10.532.091.500.500', 'D12.776.070.400.500.500', 'D12.776.521.120.500.500'], ['D10.532.091.500.750', 'D12.776.070.400.500.750', 'D12.776.521.120.500.750'], ['D10.532.091.500', 'D12.776.070.400.500', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Activation of pancreatic acinar cell phospholipase D by epidermal, insulin-like, and basic fibroblast growth factors involves tyrosine kinase. | The involvement of phospholipase D (PLD) in phosphatidylcholine hydrolysis by epidermal (EGF), insulin-like (IGF-I), and basic fibroblast (bFGF) growth factors was investigated in rat pancreatic acini. Acini were prelabeled with [3H]myristic acid which is mostly incorporated into phosphatidylcholine. EGF, IGF-I, and bF... | ['Animals', 'Enzyme Activation', 'Epidermal Growth Factor', 'Evaluation Studies as Topic', 'Fibroblast Growth Factor 2', 'Genistein', 'Insulin-Like Growth Factor I', 'Isoflavones', 'Pancreas', 'Phosphatidic Acids', 'Phosphatidylethanolamines', 'Phospholipase D', 'Protein-Tyrosine Kinases', 'Rats'] | 7,899,461 | [['B01.050'], ['G02.111.263', 'G03.328'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['E05.337', 'N05.715.360.335'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['D03.383.663.283.266.450.400.375', 'D03.633.100.150.266.450.400.375'], ['D12.644.276.937.400... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structure of a truncated form of leucine zipper II of JIP3 reveals an unexpected antiparallel coiled-coil arrangement. | JIP3 and JIP4, two highly related scaffolding proteins for MAP kinases, are binding partners for two molecular motors as well as for the small G protein ARF6. The leucine zipper II (LZII) region of JIP3/4 is the binding site for these three partners. Previously, the crystal structure of ARF6 bound to JIP4 revealed LZII... | ['Adaptor Proteins, Signal Transducing', 'Amino Acid Sequence', 'Crystallization', 'Crystallography, X-Ray', 'Humans', 'Leucine Zippers', 'Molecular Dynamics Simulation', 'Nerve Tissue Proteins', 'Peptide Fragments', 'Protein Interaction Domains and Motifs', 'Protein Structure, Secondary', 'Protein Structure, Tertiary'... | 26,919,523 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820.709.275.500.520'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D12.776.631'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Differential time domain method improves performance of pulsed laser ranging and three-dimensional imaging. | A ranging method based on the differential time domain method (DTDM) is proposed in order to improve ranging accuracy and the range of active measurement based on peak discriminator (PD). We develop mathematical models and deduce that zero-crossing sensitivity is an important factor, which affects the ranging error of ... | ['Imaging, Three-Dimensional', 'Lasers', 'Signal Processing, Computer-Assisted', 'Time Factors'] | 26,835,773 | [['E01.370.350.400', 'L01.224.308.410'], ['E07.632.490', 'E07.710.520'], ['L01.224.800'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Process and economic evaluation for monoclonal antibody purification using a membrane-only process. | In recent years, the market for therapeutic monoclonal antibodies (mAb) has grown exponentially, and with this there has been a desire to reduce the costs associated with production and purification of these high-value biological products. A typical mAb purification process involves three adsorption/chromatography step... | ['Adsorption', 'Antibodies, Monoclonal', 'Chromatography, Ion Exchange', 'Costs and Cost Analysis', 'Membranes, Artificial', 'Ultrafiltration'] | 21,618,725 | [['G01.030', 'G02.020'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.196.181.400.383'], ['N03.219.151'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E04.292.975', 'E05.196.454.807', 'G01.280.807', 'G02.263.807']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
EL-4 tumor cell-induced human and rabbit platelet aggregations. | EL-4 tumor cells were assayed in vitro for their ability to aggregate two kinds of platelets. An inhibition study showed that the EL-4 tumor cell can induce platelet aggregation by at least two different mechanisms. One, mediated by thrombin, was dominant with rabbit platelets because hirudin, which specifically inhibi... | ['Animals', 'Apyrase', 'Bucladesine', 'Cell Line', 'Hirudins', 'Humans', 'Kinetics', 'Lymphoma', 'Mice', 'Phospholipases A', 'Phospholipases A2', 'Platelet Aggregation', 'Rabbits'] | 3,015,428 | [['B01.050'], ['D08.811.277.040.050'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['A11.251.210'], ['D12.644.861.060.875', 'D12.776.872.060.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['C04.557.386', 'C15.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severity and presence of atherosclerosis signs within the segments of internal carotid artery: CBCT's contribution. | OBJECTIVES: This study aims to assess with cone-beam computed tomography the distribution and interrelation of the presence of calcifications along the course of the internal carotid artery and to associate their severity with their allocation within the segments of internal carotid artery, gender, and age.STUDY DESIGN... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Atherosclerosis', 'Carotid Artery, Internal', 'Cone-Beam Computed Tomography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radiographic Image Interpretation, Computer-Assisted', 'Retrospective Studies', 'Severity of Illness Index', 'Sex Factors'] | 27,260,278 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126.307'], ['A07.015.114.186.200.230'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.158.600.680', 'E01.370... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Sperm integrity is critical for normal mitotic division and early embryonic development. | The human zygote relies on the paternal gamete to provide the centrosome component essential for the first mitotic division. It is not known whether normal centrosome function requires an intact spermatozoon, or whether donation of an isolated paternal centrosome component can result in normal zygotes and embryos. To e... | ['Cell Nucleus', 'Chromosome Aberrations', 'Cytoplasm', 'Cytoskeleton', 'Embryo, Mammalian', 'Female', 'Fertilization in Vitro', 'Fluorescent Antibody Technique', 'Humans', 'In Situ Hybridization, Fluorescence', 'Injections', 'Male', 'Microtubules', 'Mitosis', 'Pilot Projects', 'Sperm Head', 'Sperm Tail', 'Spermatozoa'... | 10,460,222 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['C23.550.210', 'G05.365.590.175'], ['A11.284.430.214'], ['A11.284.430.214.190.750'], ['A16.254'], ['E02.875.800.750', 'E05.820.800.750'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.58... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The three methyl-CpG-binding domains of AtMBD7 control its subnuclear localization and mobility. | Three methyl-CpG-binding domain (MBD) proteins in Arabidopsis, AtMBD5, AtMBD6, and AtMBD7, are functional in binding methylated CpG dinucleotides in vitro and localize to the highly CpG-methylated chromocenters in vivo. These proteins differ, however, in their subnuclear localization pattern; AtMBD5 and AtMBD6, each co... | ['Amino Acid Motifs', 'Arabidopsis', 'Arabidopsis Proteins', 'Cell Nucleus', 'CpG Islands', 'DNA Methylation', 'DNA-Binding Proteins'] | 18,211,904 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biflavonoids from the aerial part of Stephania tetrandra. | Investigation of the aerial part of Stephania tetrandra led to the isolation of two biflavonoids, stephaflavone A and stephaflavone B, with a 3-6" linkage pattern, together with beta-sitosterol. Their structures were established on the basis of their spectroscopic data and their physicochemical properties. | ['Flavonoids', 'Molecular Structure', 'Ranunculaceae', 'Spectrum Analysis'] | 11,576,598 | [['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G02.111.570', 'G02.466'], ['B01.650.940.800.575.912.250.836.750'], ['E05.196.867']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Drug consumption of armed forces recruits (author's transl)]. | Requestioning of armed forces recruits showed partial increase of their drug consumption while in the army. The consumption of alcoholic beverages as well as cannabis increased, the level of cigaret smoking remained constant. To some extent, the recruits evaluate these changes incorrectly, since they do not always coin... | ['Adult', 'Alcohol Drinking', 'Germany, West', 'Humans', 'Male', 'Marijuana Abuse', 'Military Medicine', 'Smoking'] | 6,777,673 | [['M01.060.116'], ['F01.145.317.269'], ['Z01.586.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.775.635', 'F03.900.635'], ['H02.403.500'], ['F01.145.805']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
Use of multiple surveys to estimate mortality among never, current, and former smokers: changes over a 20-year interval. | OBJECTIVES: This study sought to demonstrate how data from publicly available large-scale cross-sectional health surveys can be combined to analyze changes in mortality risks among never, current, and former smokers.METHODS: Data from the 1966/68 and 1986 National Mortality Followback Surveys and the 1970 and 1987 Nati... | ['Adult', 'Age Distribution', 'Aged', 'Cause of Death', 'Cross-Sectional Studies', 'Data Interpretation, Statistical', 'Female', 'Follow-Up Studies', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'National Center for Health Statistics, U.S.', 'Population Surveillance', 'Sex Distribution', 'Smoking', 'United States... | 9,807,533 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.245.380', 'E05.318.740.300'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
13-Valent vaccine serotype pneumococcal community acquired pneumonia in adults in high clinical risk groups. | There is debate regarding the value of vaccinating adults with the 13-valent pneumococcal conjugate vaccine (PCV-13). This analysis was conducted to investigate the risk of PCV-13 serotype community acquired pneumonia (CAP) in hospitalised adults with co-morbid disease and risk factors for pneumococcal disease in the U... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Community-Acquired Infections', 'Comorbidity', 'Female', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Odds Ratio', 'Pneumococcal Vaccines', 'Pneumonia, Pneumococcal', 'Public Health Surveillance', 'Serogroup', 'Streptococcus pneumoniae', 'Young ... | 29,439,865 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.234'], ['N05.715.350.225', 'N06.850.490.687'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.5... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Treatment of bone and soft tissue defects in the distal part of the shank]. | Important loss of tissue in the distal third of the leg sets a difficult problem in reconstruction. The first case gives an example of a free vascularized bone graft, the second of application of the dorsalis pedis flap as an island. The indications are discussed and some points of the operative procedure are mentioned... | ['Accidents, Traffic', 'Adult', 'Bone Transplantation', 'Disasters', 'Fractures, Ununited', 'Humans', 'Leg Injuries', 'Male', 'Surgical Flaps', 'Tibial Fractures'] | 6,360,820 | [['N06.850.135.392'], ['M01.060.116'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['N06.230.100'], ['C26.404.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['A10.850.710', 'E07.862.710'], ['C26.404.875', 'C26.558.857']] | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Electroacupuncture improves cutaneous allergic reaction by inhibiting degranulation of intrape-ritoneal mast cells, MAPK signaling and inflammatory factor levels in urticaria rats]. | OBJECTIVE: To observe the effect of electroacupuncture (EA) on degranulation of intraperitoneal mast cells (MCs) and expression of mitogen-activated protein kinase (MAPK) signaling related proteins, tumor necrosis factor-á(TNF-á) and interleukin-6 (IL-6) in urticaria rats, so as to reveal its mechanisms underlying impr... | ['Acupuncture Points', 'Animals', 'Electroacupuncture', 'Mast Cells', 'Rats', 'Rats, Sprague-Dawley', 'Signal Transduction', 'Urticaria'] | 32,333,535 | [['E02.190.044.555.035'], ['B01.050'], ['E02.186.250', 'E02.190.044.244', 'E02.331.399', 'E02.779.468.399', 'E02.831.535.468.399', 'E03.091.823.500', 'E03.155.519'], ['A11.329.427', 'A15.382.652'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.111.820', 'G04.835'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Degradation of carbendazim in paddy soil and the influencing factors]. | The influences of microorganism, soil moisture and cadmium (Cd) on degradation of carbendazim in paddy soil were investigated with laboratory microcosm experiments. The results showed that the half-life of carbendazim (5.0 mg x kg(-1) and 10.0 mg x kg(-1)) in sterilized soils was 12.6-13.8 times of those in non-sterili... | ['Bacteria', 'Benzimidazoles', 'Biodegradation, Environmental', 'Carbamates', 'Crops, Agricultural', 'Soil', 'Soil Microbiology', 'Soil Pollutants'] | 23,323,435 | [['B03'], ['D03.633.100.103'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D02.241.081.251'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['D27.888.284.756']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Cerebrospinal fluid S-100beta and its relationship with AIDS dementia complex. | BACKGROUND: The astrocyte is thought to be important in AIDS dementia complex (ADC) pathogenesis on the basis of ADC neuropathology and cell culture models putatively because HIV can infect astrocytes leading to a compromise of their physiological detoxifying and neuronal support functions. Confirmatory in vivo data ar... | ['AIDS Dementia Complex', 'Biomarkers', 'Disease Progression', 'HIV-1', 'Humans', 'Nerve Growth Factors', 'S100 Calcium Binding Protein beta Subunit', 'S100 Proteins', 'Viral Load'] | 11,564,589 | [['C01.221.250.875.049', 'C01.221.812.640.400.070', 'C01.778.640.400.070', 'C01.925.782.815.616.400.049', 'C01.925.813.400.070', 'C10.228.140.380.070', 'C20.673.480.070', 'F03.615.400.050'], ['D23.101'], ['C23.550.291.656'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thauera lacus | A Gram-stain-negative, facultatively anaerobic, motile and rod-shaped bacterium, designated D20T, was isolated from the saline Lake Dai in Inner Mongolia, PR China. Growth of strain D20T occurred at 25-45 °C (optimum, 40 °C), pH 4.0-12.0 (optimum, 8.0) and with 0-3 % NaCl (w/v); (optimum, 0-1 %). The results of 16S rRN... | ['Bacterial Typing Techniques', 'Base Composition', 'China', 'DNA, Bacterial', 'Fatty Acids', 'Lakes', 'Phospholipids', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Salinity', 'Sequence Analysis, DNA', 'Thauera', 'Ubiquinone'] | 31,464,660 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['Z01.252.474.164'], ['D13.444.308.212'], ['D10.251'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D10.570.755'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['G02.640.500'], ['E05.393.760.700'], ['B03.440.425... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Cognitive mechanisms and motor control during a saccadic eye movement task: evidence from quantitative electroencephalography. | The saccadic movement is an important behavioral measure used to investigate several cognitive processes, including attention and sensorimotor integration. The present study aimed at investigating changes in beta coherence over frontal, motor, occipital, and parietal cortices during the performance of two different con... | ['Adult', 'Cerebral Cortex', 'Electroencephalography', 'Female', 'Frontal Lobe', 'Functional Laterality', 'Humans', 'Male', 'Occipital Lobe', 'Parietal Lobe', 'Saccades'] | 22,836,456 | [['M01.060.116'], ['A08.186.211.200.885.287.500'], ['E01.370.376.300', 'E01.370.405.245'], ['A08.186.211.200.885.287.500.270'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.571'], ['A08.186.211.200.885.287.500.670'], ['G14.350.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Investigation of the predictors of the response to Iguratimod therapy: A post-hoc | Objectives: The treatment response according to patient disease activity during Iguratimod therapy for rheumatoid arthritis has not been sufficiently assessed. A post-hoc analysis of post-marketing surveillance was performed. The treatment effect was evaluated using the European League against Rheumatism (EULAR) respon... | ['Adult', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Chromones', 'Drug Therapy, Combination', 'Female', 'Humans', 'Male', 'Methotrexate', 'Middle Aged', 'Product Surveillance, Postmarketing', 'Sulfonamides'] | 31,393,189 | [['M01.060.116'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.733.631.192.500'], ['M01.060.116.630'], ['E05.337.800'], ['D02.065.884', 'D02.886.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells. | BACKGROUND: Interleukin (IL)-6 plays a pivotal role in a variety of CNS functions such as the induction and modulation of reactive astrogliosis, pathological inflammatory responses and neuroprotection. Tumor necrosis factor (TNF)-alpha induces IL-6 release from rat C6 glioma cells through the inhibitory kappa B (Ikappa... | ['Acetophenones', 'Analysis of Variance', 'Animals', 'Cell Line, Tumor', 'Coumarins', 'Enzyme Inhibitors', 'Enzyme-Linked Immunosorbent Assay', 'Gene Expression Regulation, Neoplastic', 'Glioma', 'I-kappa B Proteins', 'Interleukin-6', 'Phosphorylation', 'Protein-Serine-Threonine Kinases', 'RNA, Messenger', 'Rats', 'STA... | 20,205,746 | [['D02.522.120'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D27.505.519.389'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Natural killer cell activity of mononuclear cells from rheumatoid patients measured by a conjugate-binding cytotoxicity assay. | The natural killer cell activity of synovial fluid mononuclear cells and synovial membrane mononuclear cells from patients with rheumatoid arthritis was compared with that of paired peripheral blood mononuclear cells from many of these patients. Natural killer cell activity was measured by the use of a conjugate-bindin... | ['Arthritis, Rheumatoid', 'Cytotoxicity Tests, Immunologic', 'Humans', 'Interferons', 'Killer Cells, Natural', 'Monocytes', 'Synovial Fluid', 'Synovial Membrane'] | 6,184,061 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E01.370.225.812.160', 'E05.200.812.160', 'E05.478.594.160', 'E05.940.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.53... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The sensitivity and specificity of nonmydriatic digital stereoscopic retinal imaging in detecting diabetic retinopathy. | OBJECTIVE: The objective of this study was to determine the sensitivity and specificity of Joslin Vision Network nonmydriatic digital stereoscopic retinal imaging (NMDSRI) as a screening tool in detecting diabetic retinopathy.RESEARCH DESIGN AND METHODS: We reviewed the records of 244 patients with diabetes who had a d... | ['Aged', 'Diabetic Retinopathy', 'Diagnosis, Computer-Assisted', 'Female', 'Fundus Oculi', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Mydriatics', 'Photography', 'Sensitivity and Specificity'] | 17,003,294 | [['M01.060.116.100'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E01.158', 'L01.313.500.750.100.158'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Race inequities in men's retirement. | A multistate life table model is used to identify how labor force experiences and mortality determine the labor force participation rates (LFPRs) and the qualities of the retirement life cycle of Black and White older men. LFPRs and the life cycle measures are compared to assess inequities of retirement access for the ... | ['African Americans', 'Aged', 'Disabled Persons', 'Employment', 'European Continental Ancestry Group', 'Health Status', 'Humans', 'Life Expectancy', 'Life Tables', 'Male', 'Middle Aged', 'Mortality', 'Prospective Studies', 'Quality of Life', 'Retirement', 'United States'] | 8,548,518 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['M01.150'], ['N01.824.245'], ['M01.686.508.400'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.450', 'N01.224.935.464', 'N06.850.505.400.975.450', 'N06.850.520.308.985.450'], [... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Molecular and Cytological Comparisons of Chromosomes 7el₁, 7el₂, 7E(e), and 7E ⁱ Derived from Thinopyrum. | Thinopyrum chromosomes 7el1, 7el2, 7E(e), and 7E(i), homoeologous to group 7 chromosomes of common wheat (Triticum aestivum), were determined to have many useful agronomical traits for wheat improvement. To analyze the genetic relationships among the 4 Thinopyrum 7E chromosomes, the conserved orthologous set markers, g... | ['Chromosome Mapping', 'Chromosomes, Plant', 'Genetic Markers', 'In Situ Hybridization', 'Poaceae', 'Triticum'] | 25,968,454 | [['E05.393.183'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['D23.101.387', 'G05.695.450'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['B01.650.940.800.575.912.250.822'], ['B01.650.940.800.575.912.250.822.918']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Single-level instrumented posterolateral fusion of the lumbar spine with a local bone graft versus an iliac crest bone graft: a prospective, randomized study with a 2-year follow-up. | The iliac crest bone grafting (ICBG) technique for lumbar posterolateral fusion surgery is widely used; however, donor site problems such as pain and sensory disturbance have been reported. Local bone is available for fusion surgery, but its reliability as a graft has not been fully reported. In the current study, we e... | ['Aged', 'Aged, 80 and over', 'Blood Loss, Surgical', 'Bone Transplantation', 'Disability Evaluation', 'Female', 'Follow-Up Studies', 'Humans', 'Ilium', 'Incidence', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Pain Measurement', 'Prospective Studies', 'Spinal Fusion', 'Spondylolisthesis', 'Surgical Wound Infection', 'T... | 21,165,658 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.414.300', 'C23.550.505.300'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E01.370.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Simulation of arrhythmogenic effect of rogue RyRs in failing heart by using a coupled model. | Cardiac cells with heart failure are usually characterized by impairment of Ca(2+) handling with smaller SR Ca(2+) store and high risk of triggered activities. In this study, we developed a coupled model by integrating the spatiotemporal Ca(2+) reaction-diffusion system into the cellular electrophysiological model. Wit... | ['Action Potentials', 'Arrhythmias, Cardiac', 'Calcium', 'Computer Simulation', 'Diffusion', 'Electrophysiology', 'Heart Failure', 'Heart Ventricles', 'Humans', 'Membrane Potentials', 'Models, Statistical', 'Models, Theoretical', 'Muscle Cells', 'Ryanodine Receptor Calcium Release Channel', 'Time Factors'] | 23,056,145 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['C14.280.067', 'C23.550.073'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['L01.224.160'], ['G01.202', 'G02.196'], ['H01.158.344.528', 'H01.158.782.236'], ['C14.280.434'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.154.535... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
An association study of dopamine receptors polymorphisms and the Wisconsin Card Sorting Test in schizophrenia. | Dopamine (DA), an important neurotransmitter in prefrontal cortex (PFC), is involved in the pathogenesis of schizophrenia. The aim of the study was to test an association between common polymorphism of genes for DA receptors DRD1, DRD2, DRD3, DRD4, and performance on the Wisconsin Card Sorting Test (WCST), measuring va... | ['Adolescent', 'Adult', 'Brain', 'Brain Chemistry', 'DNA Mutational Analysis', 'Dopamine', 'Female', 'Genetic Predisposition to Disease', 'Genetic Testing', 'Genotype', 'Humans', 'Male', 'Mutation', 'Neuropsychological Tests', 'Polymorphism, Genetic', 'Prefrontal Cortex', 'Receptors, Dopamine', 'Schizophrenia', 'Schizo... | 15,785,860 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['E05.393.760.700.300'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['C23.550.291.687.500', 'G05.380.355'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'],... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance. | Taxanes act by inhibiting microtubule dynamics; in this study, we have investigated mitochondria as an additional target of taxanes. We incubated isolated mitochondria in the presence of taxanes with or without stimulation of the mitochondrial respiratory state. Results showed that they rapidly induced the loss of delt... | ['Antineoplastic Agents, Phytogenic', 'Blotting, Western', 'Down-Regulation', 'Drug Resistance, Neoplasm', 'Humans', 'Mitochondria', 'Paclitaxel', 'Proto-Oncogene Proteins c-bcl-2', 'Reverse Transcriptase Polymerase Chain Reaction', 'Tumor Cells, Cultured'] | 12,815,160 | [['D27.505.954.248.179'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D02.455.426.39... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of TGF-â1 on Apoptosis of Colon Cancer Cells Via the ERK Signaling Pathway. | PURPOSE: To study the effect of transforming growth factor (TGF)-â1 on apoptosis of colon cancer cells via the ERK signaling pathway.METHODS: Human chemosensitive colon cancer cell line HT- 29 was used in this study. VEGF mRNA and protein level were detected using PCR and western blot. Enzyme-linked immunosorbent assay... | ['Apoptosis', 'Cell Proliferation', 'Colon', 'Colonic Neoplasms', 'Cyclooxygenase 2', 'Etoposide', 'Fluorouracil', 'Gene Expression Regulation, Neoplastic', 'HT29 Cells', 'Humans', 'MAP Kinase Signaling System', 'Mitogen-Activated Protein Kinase 1', 'Reactive Oxygen Species', 'Transforming Growth Factor beta1'] | 31,127,990 | [['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D08.811.600.720.750'], ['D02.455.426.559.847.638.960.675.250', 'D04... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vascular tumors and malformations in children, Introduction. | Over the past decade, I have been amazed at the growth in the field of vascular anomalies. The recognition of vascular birthmarks as a defined area of medicine is a relatively recent event. The International Society for the Study of Vascular Anomalies (ISSVA) was founded by Drs John Mulliken and Anthony Young in the la... | ['Arteriovenous Malformations', 'Child', 'Hemangioma', 'Humans', 'Terminology as Topic', 'Vascular Malformations', 'Vascular Neoplasms'] | 27,607,317 | [['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['M01.060.406'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.400'], ['C14.240.850', 'C16.131.240.850'], ['C04.588.839.750', 'C14.907.936']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Behavior of Listeria monocytogenes during processing and storage of experimentally contaminated hot-smoked trout. | Hot-smoked fish like smoked trout is quite frequently contaminated with Listeria monocytogenes. In order to estimate the potential health hazard for the consumer eating such products, the behavior of L. monocytogenes was studied during processing and storage of artificially-inoculated hot-smoked trout. Four trials were... | ['Animals', 'Food Handling', 'Food Microbiology', 'Food Preservation', 'Humans', 'Listeria monocytogenes', 'Meat', 'Risk Factors', 'Smoke', 'Trout'] | 1,419,540 | [['B01.050'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['J01.576.423.850.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'],... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Immunomodulatory effects of vitamin D3 and bisphosphonates in nutritional osteoporosis in rats]. | The aim of this study was to determine the effectiveness of separate and combined administration of vitamin D3 and different forms of bisphosphonate (disodium salt of methylenbisphosphonic acid dihydrate and alendronate) on the function of immune cells in rats with nutritional osteoporosis. It was shown that D-hypovita... | ['Animals', 'B-Lymphocytes', 'Bone Density Conservation Agents', 'Bone and Bones', 'Calcifediol', 'Calcium', 'Cholecalciferol', 'Diphosphonates', 'Drug Combinations', 'Flow Cytometry', 'Granulocytes', 'Immunity, Humoral', 'Immunoglobulins', 'Immunomodulation', 'Male', 'Monocytes', 'Osteoporosis', 'Phagocytosis', 'Rats'... | 22,642,124 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D27.505.696.242'], ['A02.835.232', 'A10.165.265'], ['D04.210.500.247.222.159.478.250', 'D04.210.500.247.808.146.478.250', 'D04.210.500.812.768.196.478.250', 'D10.570.938.146.478.250']... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The humoral immune responses of patients bitten by the snake Bothrops jararaca (jararaca). | The isotype and specificity of antibodies produced by patients bitten by B. jararaca and submitted to serum therapy were studied. The IgG anti-B. jararaca antibodies have large individual dispersion, starting to appear 10 days after the first bite and increasing to at least 80 days after the bite. IgM antibodies appear... | ['Crotalid Venoms', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoblotting', 'Immunoglobulin G', 'Immunoglobulin M', 'Snake Bites'] | 2,402,767 | [['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Very clever homunculus: compound stimulus strategies for the explicit task-cuing procedure. | In two experiments, subjects were given arbitrary letter cues or meaningful word cues that specified the task to be performed on a subsequent target stimulus. Letter and word cues were presented in separate blocks. There were two cues of each type for each task. Three kinds of transitions separated tasks: cue repetitio... | ['Cognition', 'Cues', 'Fixation, Ocular', 'Humans', 'Models, Psychological', 'Reaction Time'] | 15,732,691 | [['F02.463.188'], ['F02.463.425.234'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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