Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcriptional regulation of the plastocyanin and cytochrome c553 genes from the cyanobacterium Anabaena species PCC 7937. | The effect of copper on the levels of plastocyanin (PC) and cytochrome c553 (cyt-c)-specific transcripts from Anabaena sp. PCC 7937 was investigated. The addition of copper resulted in a marked increase in PC mRNA levels, and a decrease in cyt c mRNA levels. Thus the functional exchange between PC and cyt c seems to be... | ['Anabaena', 'Base Sequence', 'Chloramphenicol', 'Copper', 'Cytochrome c Group', 'Gene Expression Regulation, Bacterial', 'Kinetics', 'Molecular Sequence Data', 'Plastocyanin', 'Protein Biosynthesis', 'RNA, Messenger', 'Rifampin', 'Transcription, Genetic'] | 1,320,727 | [['B03.280.100', 'B03.440.475.100.100', 'B03.585.051'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D08.244.286', 'D12.776.422.220.286'], ['G05.308.300'], ['G01.374.661'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In-office dental bleaching with light vs. without light: A systematic review and meta-analysis. | OBJECTIVE: A systematic review and meta-analysis were performed to answer the following research question: Does light-activated in-office vital bleaching have a greater whitening efficacy and higher tooth sensitivity (TS) in comparison with in-office vital bleaching without light when used in adults?DATA AND SOURCE: On... | ['Adult', 'Databases, Factual', 'Dental Offices', 'Dentin Sensitivity', 'Humans', 'Hydrogen Peroxide', 'Light', 'Tooth Bleaching', 'Tooth Bleaching Agents'] | 29,289,725 | [['M01.060.116'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['N02.278.192.377'], ['C07.793.266'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.75... | ['Named Groups [M]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Foreign bodies of the bladder. Report of a new case]. | In this paper we are relating the medical history of 30 year-old female patient with psychiatric medical background. This patient introduced multiple foreign bodies in her bladder via the urethra. Throughout this observation, we analyse diagnosis and therapeutic aspects of bladder foreign bodies. | ['Adult', 'Female', 'Foreign Bodies', 'Humans', 'Urinary Bladder'] | 11,496,598 | [['M01.060.116'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.890']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Norms-based assessment of patient-reported outcomes associated with adalimumab monotherapy in patients with ankylosing spondylitis. | OBJECTIVES: To compare the impact of ankylosing spondylitis (AS) on health-related quality of life (HRQL) and of adalimumab on initial and sustained improvement in HRQL for patients with active AS versus the general US population.METHODS: Data from the 5-year ATLAS trial were analysed. HRQL burden of AS and treatment i... | ['Adalimumab', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Inflammatory Agents', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Cost of Illness', 'Disability Evaluation', 'Double-Blind Method', 'Female', 'Health Status', 'Health Status Indicators', 'Health Surveys', 'Humans', 'Male', 'Mid... | 21,813,060 | [['D12.776.124.486.485.114.224.060.250', 'D12.776.124.790.651.114.224.060.250', 'D12.776.377.715.548.114.224.200.250'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.158'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D1... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Clinical value of thymidine kinase and tissue polypeptide specific antigen in breast cancer. | Thymidine kinase (TK) and tissue polypeptide specific antigen (TPS) were determined in breast cancer (BC) patients (n = 83), normal healthy women (n = 30) and 18 women with different benign mastopathies. Mean serum levels of TK and TPS in BC patients showed significant increases from their corresponding levels in healt... | ['Biomarkers, Tumor', 'Bone Neoplasms', 'Breast Neoplasms', 'Female', 'Humans', 'Mastectomy, Radical', 'Peptides', 'Postoperative Period', 'Prognosis', 'Tamoxifen', 'Thymidine Kinase', 'Tissue Polypeptide Antigen'] | 8,112,021 | [['D23.101.140'], ['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466.678'], ['D12.644'], ['E04.614.750', 'N02.421.585.753.750'], ['E01.789'], ['D02.455.426.559.389.150.700.900'], ['D08.811.913.696.620.750'], ['D12.644.875', 'D23.050.285.840', '... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Detection systems for carbapenemase gene identification should include the SME serine carbapenemase. | Carbapenemase detection has become a major problem in hospitals that encounter outbreaks of infections caused by carbapenem-resistant Gram-negative bacteria. Rapid detection systems have been reported using multiplex PCR analyses and DNA microarray assays. Major carbapenemases that are detected by these systems include... | ['Bacterial Proteins', 'Bacteriological Techniques', 'Humans', 'Multiplex Polymerase Chain Reaction', 'North America', 'Oligonucleotide Array Sequence Analysis', 'Serratia Infections', 'Serratia marcescens', 'South America', 'beta-Lactamases'] | 23,219,246 | [['D12.776.097'], ['E01.370.225.875.150', 'E05.200.875.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500.487'], ['Z01.107.567'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['C01.150.252.400.310.850'], ['B03.440.450.425.814.664', 'B03.660.250.150.720.500'], ['Z01.10... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Cloning and expression of MRG receptors in macaque, mouse, and human. | Members of the MRG family of G-protein coupled receptors (GPCRs) are expressed predominately in small diameter sensory neurons of the dorsal root ganglia (DRG) suggesting a possible role in nociception. However, the large expansion of this gene family in rodents, combined with the lack of strict rodent orthologs for ma... | ['Animals', 'Blotting, Northern', 'Blotting, Southern', 'Brain', 'Cloning, Molecular', 'DNA, Complementary', 'Ganglia, Spinal', 'Gene Expression', 'Gene Expression Regulation', 'Glycoproteins', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Macaca fascicularis', 'Mice', 'Molecular Sequence Data', 'Multigen... | 15,710,235 | [['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['A08.186.211'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.297'], ['G... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Disclosing special needs to parents. Have we got it right yet? | Parents' perceptions of how they were told that their child has special needs were examined. Thirty-nine families on the Isle of Wight completed a structured interview. Participants formed two groups. The first group comprised of 23 families who had a child aged from birth to 5 years with special needs. In the second g... | ['Adolescent', 'Adult', 'Channel Islands', 'Child', 'Child, Preschool', 'Consumer Behavior', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Intellectual Disability', 'Learning Disabilities', 'Male', 'Parents', 'Truth Disclosure'] | 9,921,417 | [['M01.060.057'], ['M01.060.116'], ['Z01.542.363.161'], ['M01.060.406'], ['M01.060.406.448'], ['F01.145.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['C10.597.606.150.550', 'C23.888.592.604.150.550... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Quantitative aspects of calcium fluorimetry. | Ca(2+) indicator dyes by necessity are Ca(2+) chelators, because it is the binding of Ca(2+) to dye molecules that induces the change in fluorescence on which the Ca(2+) signal is based. As chelators, once introduced into a cell, they contribute to cellular Ca(2+) buffering. It has been a question of much debate to wha... | ['Buffers', 'Calcium', 'Chelating Agents', 'Cytological Techniques', 'Fluorometry', 'Fura-2', 'Staining and Labeling'] | 24,086,061 | [['D27.720.470.280'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.914.500', 'D27.720.832.500'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['E05.196.712.516.600'], ['D03.383.129.462.285', 'D03.633.100.127.250'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The preparticipation physical examination history: who has the correct answers? | OBJECTIVE: To examine whether discrepancies exist between information given by parents and student athletes during the annual preparticipation physical examination (PPE) for athletics, and if present, whether the discrepancies occurred in areas of clinical significance to sports medicine and clearance for participation... | ['Adolescent', 'Athletic Injuries', 'Data Collection', 'Female', 'Humans', 'Male', 'Medical History Taking', 'Parents', 'Physical Examination', 'School Health Services', 'Sensitivity and Specificity', 'South Carolina', 'Sports', 'Students', 'Surveys and Questionnaires'] | 10,512,339 | [['M01.060.057'], ['C26.115'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.510'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E01.370.600'], ['N02.421.726.809'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Cerebral vascular adaptation to pregnancy and its role in the neurological complications of eclampsia. | The cerebral circulation has a central role in mediating the neurological complications of eclampsia, yet our understanding of how pregnancy and preeclampsia affect this circulation is severely limited. Here, we show that pregnancy causes outward remodeling of penetrating arterioles and increased capillary density in t... | ['Animals', 'Blood Flow Velocity', 'Cerebral Arteries', 'Cerebrovascular Circulation', 'Cerebrovascular Disorders', 'Eclampsia', 'Female', 'Nervous System Diseases', 'Pre-Eclampsia', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Vascular Resistance'] | 21,071,591 | [['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A07.015.114.228'], ['G09.330.100.159'], ['C10.228.140.300', 'C14.907.253'], ['C13.703.395.124'], ['C10'], ['C13.703.395.249'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G09.330.380.921'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Decolorization and biodegradation of Reactive Blue 13 by Proteus mirabilis LAG. | The decolorization and biodegradation of Reactive Blue 13 (RB13), a sulphonated reactive azo dye, was achieved under static anoxic condition with a bacterial strain identified as Proteus mirabilis LAG, which was isolated from a municipal dump site soil near Lagos, Nigeria. This strain decolorized RB13 (100mg/l) within ... | ['Biodegradation, Environmental', 'Color', 'Coloring Agents', 'Gas Chromatography-Mass Spectrometry', 'Proteus mirabilis'] | 20,832,936 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['G01.590.540.199'], ['D27.720.233'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B03.440.450.425.600.501', 'B03.660.250.150.590.500']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A facilitatory effect on the induction of long-term potentiation in vivo by chronic administration of antisense oligodeoxynucleotides against catalytic subunits of calcineurin. | A rise in Ca2+ concentration at postsynaptic sites provides an initial step in inducing both the long-term potentiation (LTP) and long-term depression (LTD) in the CA1 region of the hippocampus. LTP induction requires the activation of Ca(2+)-sensitive protein kinases following the rise in Ca2+. By contrast, the activi... | ['Animals', 'Binding Sites', 'Calcineurin', 'Calcium', 'Calmodulin', 'Calmodulin-Binding Proteins', 'Hippocampus', 'Long-Term Potentiation', 'Male', 'Nerve Tissue Proteins', 'Oligonucleotides, Antisense', 'Phosphoprotein Phosphatases', 'Phosphorylation', 'Protein Processing, Post-Translational', 'Rats', 'Rats, Wistar',... | 8,883,951 | [['B01.050'], ['G02.111.570.120'], ['D08.811.277.352.650.625.150', 'D12.644.360.087', 'D12.776.476.087'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D12.776.157.142'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic recombination between malignant hyperthermia and calcium release channel in skeletal muscle. | Absolute linkage between the gene, on chromosome 19, for the calcium release channel (CRC) of the sarcoplasmic reticulum in skeletal muscle and malignant hyperthermia (MH) has been reported by other workers. In the present study of three Swedish Families informative with respect to this linkage relationship, definite r... | ['Alleles', 'Calcium Channels', 'Chromosomes, Human, Pair 19', 'Female', 'Genetic Linkage', 'Humans', 'Male', 'Malignant Hyperthermia', 'Muscles', 'Pedigree', 'Phenotype', 'Recombination, Genetic'] | 1,318,804 | [['G05.360.340.024.340.030'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['A11.284.187.520.300.460.465', 'G05.360.162.520.300.460.465'], ['G05.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505.700', 'C23.550.767.600'], ['A02.633', 'A10.690'], ['E05.393.673'], ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differentiated expression of membrane type metalloproteinases (MMP-14, MMP-15) and pro-MMP2 in laryngeal squamous cell carcinoma. A novel mechanism. | Cancer progression involves multiple proteolytic interactions, with metalloproteinases (MMPs) performing a crucial role. MMP-2, a major MMP, plays a key role in the degradation of basement membranes. Mechanisms underlying MMP-2 activation had to be investigated. Membrane-type matrix metalloproteinases are not only resp... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Cell Membrane', 'Cytoplasm', 'Disease Progression', 'Enzyme Precursors', 'Epithelium', 'Female', 'Gelatinases', 'Humans', 'Immunohistochemistry', 'Laryngeal Mucosa', 'Laryngeal Neoplasms', 'Lymphatic Metastasis', 'Male', 'Matrix Metalloproteinase 14', 'Matrix Metalloprotei... | 22,998,427 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.284.149'], ['A11.284.430.214'], ['C23.550.291.656'], ['D08.622', 'D12.776.811.243'], ['A10.272'], ['D08.811.277.656.300.480.252', 'D08.811.277.656.675.374.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.50... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Scedosporium apiospermum disseminated infection in a single lung transplant recipient]. | BACKGROUND: Scedosporium spp. are filamentous fungi, and the 2 most important species are Scedosporium prolificans and Scedosporium apiospermum. S. apiospermum accounts for approximately 25% of non-Aspergillus filamentous fungi infections in organ transplant recipients. Scedosporium can colonize the sinuses and airways... | ['Amphotericin B', 'Antifungal Agents', 'Candidiasis', 'Combined Modality Therapy', 'Cross Infection', 'Debridement', 'Deoxycholic Acid', 'Drug Combinations', 'Fatal Outcome', 'Fungemia', 'Graft Rejection', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Immunocompromised Host', 'Immunosuppressive Agents', 'Itraconazole', ... | 21,700,235 | [['D02.540.576.500.500'], ['D27.505.954.122.136'], ['C01.150.703.160'], ['E02.186'], ['C01.248', 'C23.550.291.875.500'], ['E04.176'], ['D04.210.500.105.225.272', 'D04.210.500.221.430.342'], ['D26.310'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of gender on access to the renal transplant waiting list for pediatric and adult patients. | While the public and policy-makers place a priority on equity in the organ allocation process, several studies suggest that women may be less likely than men to receive a renal transplant. However, the cause of this disparity and whether it exists among children with end-stage renal disease (ESRD) are unknown. To addre... | ['Adolescent', 'Adult', 'Aged', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Cohort Studies', 'Confounding Factors, Epidemiologic', 'Female', 'Health Services Accessibility', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Proportional Hazards M... | 10,770,976 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.240', 'N06.850.490.718'], ['N04.590.374... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mycobacterium marinum infection. | A 64-year-old man presented for evaluation of tender pustules that developed on his right hand and subsequently spread up his arms in a sporotrichoid manner. Owing to the prominent history of recent trauma followed by fish tank exposure, the patient was started on doxycycline for coverage of Mycobacterium marinum. Subs... | ['Animals', 'Doxycycline', 'Fishes', 'Hand Dermatoses', 'Humans', 'Male', 'Middle Aged', 'Mycobacterium Infections, Nontuberculous', 'Mycobacterium marinum', 'Thumb', 'Water Microbiology', 'Wound Infection'] | 19,061,606 | [['B01.050'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['B01.050.150.900.493'], ['C17.800.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.150.252.410.040.552.475'], ['B03.510.024.962.500.720.500', 'B03.510.460.400.410.552.552.720.500'], ['A01.378.800.667.430.705'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficient error correction for next-generation sequencing of viral amplicons. | BACKGROUND: Next-generation sequencing allows the analysis of an unprecedented number of viral sequence variants from infected patients, presenting a novel opportunity for understanding virus evolution, drug resistance and immune escape. However, sequencing in bulk is error prone. Thus, the generated data require error... | ['Algorithms', 'Cluster Analysis', 'Computational Biology', 'DNA, Viral', 'Haplotypes', 'Sequence Analysis, DNA', 'Viruses'] | 22,759,430 | [['G17.035', 'L01.224.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['D13.444.308.568'], ['G05.380.360'], ['E05.393.760.700'], ['B04']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
The Bifidobacterium longum NCIMB 702259T ctr gene codes for a novel cholate transporter. | Preexposure of Bifidobacterium longum NCIMB 702259T to cholate caused increased resistance to cholate, chloramphenicol, and erythromycin. The B. longum ctr gene, encoding a cholate efflux transporter, was transformed into the efflux-negative mutant Escherichia coli KAM3, conferring resistance to bile salts and other an... | ['Amino Acid Sequence', 'Anti-Bacterial Agents', 'Bacterial Proteins', 'Bifidobacterium', 'Bile Acids and Salts', 'Carbon Radioisotopes', 'Chloramphenicol', 'Cholates', 'Drug Resistance, Bacterial', 'Erythromycin', 'Membrane Transport Proteins', 'Microbial Sensitivity Tests', 'Molecular Sequence Data'] | 16,391,136 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.954.122.085'], ['D12.776.097'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['D04.210.500.105'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['D04.210.500.105.225.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Heimlich valve treatment of Pneumocystis carinii-associated pneumothorax. | Two patients were treated for AIDS-associated bilateral pneumothoraces which persisted despite prolonged chest tube drainage. Heimlich flutter valves were used to facilitate the outpatient management of these patients. | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Chest Tubes', 'Drainage', 'Humans', 'Lung', 'Male', 'Pneumonia, Pneumocystis', 'Pneumothorax', 'Radiography'] | 2,060,370 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['E07.858.150'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C01.150.703.534.700', 'C01.150... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic profiling of the Azores Islands (Portugal): data from 10 X-chromosome STRs. | The populations from the Azores islands have been the target of several genetic studies, using data derived from monoparental and recombining genetic systems. These studies have provided a complex picture of the genetic landscape of the three groups of Azorean islands, and further data are required to assess its geneti... | ['Azores', 'Chromosomes, Human, X', 'Female', 'Gene Frequency', 'Genetic Loci', 'Genetic Markers', 'Haplotypes', 'Humans', 'Male', 'Polymorphism, Genetic', 'Population', 'Portugal'] | 19,593,741 | [['Z01.639.040.218'], ['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['G05.330'], ['G05.360.340.024.380'], ['D23.101.387', 'G05.695.450'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795'], ['N01.600'], ['Z01.542.727'... | ['Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effects of the submarine environment on renal-stone risk factors and vitamin D metabolism. | The effects of total sunlight deprivation on urinary risk factors for nephrolithiasis and vitamin D metabolism were studied in 20 healthy male subjects. Blood and 24-h urine samples were collected before submarine deployment and 68 days later while still at sea. No subject received sunlight exposure during the test int... | ['Adult', 'Creatinine', 'Diving', 'Humans', 'Kidney Calculi', 'Male', 'Parathyroid Hormone', 'Phosphorus', 'Risk Factors', 'Sodium', 'Sulfates', 'Vitamin D'] | 7,633,276 | [['M01.060.116'], ['D03.383.129.308.207'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Blockade of cardiac Na+ channels by a charged class I antiarrhythmic agent, bisaramil: possible interaction of the drug with a pre-open closed state. | The mechanism of cardiac Na+ channel block by a charged class I antiarrhythmic agent, bisaramil, was studied in guinea-pig ventricular myocytes using patch-clamp techniques of whole-cell, cell-attached and inside-out configurations. Bath application of bisaramil caused the use-dependent block of whole cell Na+ current ... | ['Animals', 'Anti-Arrhythmia Agents', 'Binding Sites', 'Bridged Bicyclo Compounds, Heterocyclic', 'Chlorobenzenes', 'Guinea Pigs', 'Heart', 'Kinetics', 'Myocardium', 'Sodium Channel Blockers', 'Sodium Channels'] | 8,894,603 | [['B01.050'], ['D27.505.954.411.097'], ['G02.111.570.120'], ['D03.605.084'], ['D02.455.426.559.389.261', 'D02.455.526.439.202'], ['B01.050.150.900.649.313.992.550'], ['A07.541'], ['G01.374.661', 'G02.111.490'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D27.505.519.562.750', 'D27.505.954.411.720'], ['D12.776.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationships of fear, anxiety, and depression with physical function in patients with knee osteoarthritis. | OBJECTIVES: To explore whether the psychologic variables anxiety, depression, and fear-avoidance beliefs, and interactions between these variables, are associated with physical function in patients with knee osteoarthritis (OA). We hypothesized lower levels of function would be related to higher anxiety, higher depress... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anxiety', 'Cross-Sectional Studies', 'Depression', 'Disability Evaluation', 'Fear', 'Female', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Psychiatric Status Rating Scales'] | 19,887,210 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['E01.370.400'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Results of penetrating keratoplasty for pseudophakic bullous keratopathy with the exchange of an intraocular lens. | We report on 29 consecutive patients with pseudophakic bullous keratopathy who underwent in one eye penetrating keratoplasty with an exchange of the original intraocular lens for a Pearce tripod posterior chamber lens, and who were available for a follow up of at least 12 months. The average interval between cataract e... | ['Aged', 'Aged, 80 and over', 'Cataract Extraction', 'Corneal Diseases', 'Corneal Edema', 'Female', 'Humans', 'Keratoplasty, Penetrating', 'Lenses, Intraocular', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Visual Acuity'] | 2,804,025 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.540.825.249'], ['C11.204'], ['C11.204.267'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.225.350', 'E04.540.825.374.350', 'E04.936.580.225.350'], ['E07.632.500.460', 'E07.695.460'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.500.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Turnover of apoE in normal and hypercholesterolemic rats. | The turnover of apoE in the total lipoprotein fraction (p less than 1.21 g/ml) of normolipemic and hypercholesterolemic rats was compared. The specific activity of 125I-labelled apoE in the lipoproteins was determined after isolation of the apoprotein by immunoaffinity chromatography. The serum apoE decay curves showed... | ['Animals', 'Apoenzymes', 'Apoproteins', 'Cholesterol', 'Chylomicrons', 'Half-Life', 'Hypercholesterolemia', 'Lipoproteins', 'Male', 'Rats'] | 518,738 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characteristics of victims coarrested for intimate partner violence. | This study evaluated the frequency of coarrest in female victims who utilized 911 for intimate partner violence (IPV) and any patterns or circumstances that increased the likelihood of coarrest. All cases of police-documented IPV where a female IPV victim was arrested in conjunction with the perpetrator were included. ... | ['Adolescent', 'Adult', 'Aggression', 'Crime Victims', 'Female', 'Humans', 'Incidence', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Police', 'Prisoners', 'Records', 'Socioeconomic Factors', 'Spouse Abuse', 'Substance-Related Disorders', 'United States'] | 17,057,163 | [['M01.060.057'], ['M01.060.116'], ['F01.145.126.125', 'F01.145.813.045'], ['M01.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['F01.829.401'], ['M01.060.116.630'], ['M01.526.373.750', 'M01.526.76... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Antidiabetic action of vanadyl in rats independent of in vivo insulin-receptor kinase activity. | The effects of oral vanadyl sulfate administration for 9-12 days on carbohydrate and lipid metabolism in the basal state and on glucose dynamics during submaximal hyperinsulinemic clamps were investigated in nondiabetic and streptozocin-induced diabetic rats. Decreases in growth rate and water and food consumption were... | ['Animals', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Hypoglycemic Agents', 'Kinetics', 'Liver', 'Male', 'Protein-Tyrosine Kinases', 'Rats', 'Rats, Inbred Strains', 'Receptor, Insulin', 'Reference Values', 'Vanadates'] | 1,849,104 | [['B01.050'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D27.505.696.422'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['D08.811.913.696.620.682.725'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A program for the control of indoor pollution by metallic mercury. | The objective of this study was to develop an educational program for preventing metallic mercury emissions due to the burning of mercury-gold amalgams inside houses. The main participants were adolescents from a school in the city of Pocon?, State of Mato Grosso. The program was developed in five stages, including dis... | ['Adolescent', 'Adolescent Behavior', 'Air Pollution, Indoor', 'Education', 'Female', 'Gold', 'Humans', 'Male', 'Mercury', 'Metallurgy', 'Urban Population'] | 10,856,183 | [['M01.060.057'], ['F01.145.022'], ['N06.850.460.100.080'], ['I02'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['J01.576.655.875.400'], ['N01.600.900']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Analysis of naturally-occurring radionuclides in coal combustion fly ash, gypsum, and scrubber residue samples. | Coal combustion residues from coal-fired power plants can be advantageous for use in building and construction materials. These by-products contain trace quantities of naturally occurring radionuclides from the uranium and thorium series, as well as other naturally occurring radionuclides such as K. Analysis was perfor... | ['Calcium Sulfate', 'Coal', 'Coal Ash', 'Radioisotopes', 'Sewage'] | 23,361,421 | [['D01.146.375', 'D01.578.215', 'D01.875.800.800.850.125'], ['D20.345.108', 'N06.230.132.258.108'], ['D20.633.110'], ['D01.496.749'], ['D20.944.932.500']] | ['Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Histologic analysis of microinvasive carcinoma of the cervix uteri with graphic reconstruction]. | To seize the aspect of microinvasive carcinoma in relation to C.I.S., graphic reconstruction of 37 cases, comprising 31 cases of Stage Ia and 6 cases with confluent invasion to a depth of 5mm or less, were represented in detailed schematic drawings. From a new approach to analysis, the following conclusions could be dr... | ['Carcinoma', 'Epithelium', 'Female', 'Humans', 'Models, Biological', 'Neoplasm Invasiveness', 'Uterine Cervical Neoplasms'] | 3,701,136 | [['C04.557.470.200'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['C04.697.645', 'C23.550.727.645'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.852.762.850', 'C13.351.937.418.875.850']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studying the genotoxic effects induced by two kinds of bentonite particles on human B lymphoblast cells in vitro. | The aim of the present study was to evaluate the genotoxic effects induced by native and active bentonite particles (BPs) on human B lymphoblast cells using comet assay and cytokinesis-block micronucleus (CBMN) assay in vitro. The cells were exposed to BPs at the concentrations of 30, 60, 120 and 240ìg/ml for 24, 48 an... | ['B-Lymphocytes', 'Bentonite', 'Cell Line', 'Comet Assay', 'DNA Damage', 'Dose-Response Relationship, Drug', 'Humans', 'Micronucleus Tests', 'Solubility'] | 21,215,817 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D01.056.050.075.100', 'D01.578.725.025.100', 'D01.650.550.050.075.100', 'D01.837.725.700.760.050.100'], ['A11.251.210'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stimulatory catfish leukocyte immune-type receptors (IpLITRs) demonstrate a unique ability to associate with adaptor signaling proteins and participate in the formation of homo- and heterodimers. | Channel catfish leukocyte immune-type receptors (IpLITRs) are immunoglobulin superfamily (IgSF) members believed to play a role in the control and coordination of cellular immune responses. Some IpLITR-types encode a transmembrane (TM) region containing a single positive charged lysine (K) residue, which is a key featu... | ['Adaptor Proteins, Signal Transducing', 'Amino Acid Motifs', 'Animals', 'Catfishes', 'Cell Membrane', 'Cytoplasm', 'Leukocytes', 'Mutagenesis, Site-Directed', 'Protein Multimerization', 'Receptors, Immunologic', 'Subcellular Fractions'] | 19,800,691 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['B01.050'], ['B01.050.150.900.493.080'], ['A11.284.149'], ['A11.284.430.214'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['E05.393.420.601.575'], ['G02.111.694'], ['D12.776.543.750.705']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thyrotropin-releasing hormone and lysine-bradykinin stimulate arachidonate liberation from rat anterior pituitary cells through different mechanisms. | TRH and lysine-bradykinin (Lys-bradykinin) increase PRL release and arachidonate liberation from anterior pituitary cells. We investigated whether the arachidonate liberation stimulated by TRH and Lys-bradykinin originates in pituitary lactotropes and whether these events are accomplished through similar mechanisms. Ly... | ['Animals', 'Arachidonic Acids', 'Cells, Cultured', 'Female', 'Kallidin', 'Kinetics', 'Pituitary Gland, Anterior', 'Prolactin', 'Rats', 'Rats, Inbred Strains', 'Stearic Acids', 'Thyrotropin-Releasing Hormone', 'Time Factors', 'Tritium'] | 1,505,463 | [['B01.050'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['A11.251'], ['D12.644.276.812.169.400', 'D12.644.456.193.400', 'D12.776.467.812.169.400', 'D23.469.050.375.110.400', 'D23.529.812.169.400'], ['G01.374.661', 'G02.111.490'], ['A06.300.747.500', 'A06.688.357.750.500', 'A08.186.211.180.497.352.435.500.500', 'A... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SHUGOSHINs and PATRONUS protect meiotic centromere cohesion in Arabidopsis thaliana. | In meiosis, chromosome cohesion is maintained by the cohesin complex, which is released in a two-step manner. At meiosis I, the meiosis-specific cohesin subunit Rec8 is cleaved by the protease Separase along chromosome arms, allowing homologous chromosome segregation. Next, in meiosis II, cleavage of the remaining cent... | ['Arabidopsis', 'Arabidopsis Proteins', 'Cell Cycle Proteins', 'Centromere', 'Chromosome Segregation', 'Meiosis', 'Mitosis', 'Spindle Apparatus'] | 24,506,176 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D12.776.167'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['G04.144.220.220.625', 'G05.113.220.625'], ['G04.144.220.220.687', 'G05.113.220.687'], ['G04.144.220.220.781', 'G05.113.220.781'], ['A11.284.430.214.190.750.820']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ten years experience of thoracic and thoracoabdominal aortic aneurysm surgical repair: lessons learned. | In the last few years, advances in surgical techniques and in organ protection adjuncts have improved outcomes in thoracic (TAA) and thoracoabdominal aortic aneurysm (TAAA) surgical repair, although mortality and morbidity are still noteworthy. The aim of the current retrospective study is to determine whether the use ... | ['Aged', 'Aortic Aneurysm, Abdominal', 'Aortic Aneurysm, Thoracic', 'Arteriovenous Shunt, Surgical', 'Extracorporeal Circulation', 'Female', 'Hospital Mortality', 'Humans', 'Intraoperative Care', 'Magnetic Resonance Angiography', 'Male', 'Paraplegia', 'Postoperative Complications', 'Respiratory Insufficiency', 'Retrosp... | 15,534,729 | [['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['E04.035.087', 'E04.100.814.868.249'], ['E04.292'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate. | BAL1 is a transcription modulator that is overexpressed in chemoresistant, diffuse large B-cell lymphomas (DLBCLs). BAL1 complexes with a recently described DELTEX family member termed BBAP. Herein, we characterized BAL1 and BBAP expression in primary DLBCL subtypes defined by their comprehensive transcriptional profil... | ['Base Sequence', 'Cell Line, Tumor', 'Chromosomes, Human, Pair 3', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Interferon-gamma', 'Janus Kinase 2', 'Lymphoma, B-Cell', 'Lymphoma, Large B-Cell, Diffuse', 'Mutation', 'Neoplasm Proteins', 'Poly(ADP-ribose) Polymerases', 'Promoter Regions, Genetic', 'Protein-Tyro... | 16,809,771 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.187.520.300.235.250', 'G05.360.162.520.300.235.250'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vivo evaluation of gene transfer into mesenchymal cells (in view of cartilage repair). | Gene transfer of specific growth factors is suitable for inducing chondrogenic differentiation of -mesenchymal cells to be used for cartilage regeneration. However, extent and quality of repair tissue formation also depend on biomechanical and metabolic influences that can only be studied in vivo. We describe three met... | ['Adenoviridae', 'Animals', 'Cartilage', 'Cartilage, Articular', 'Cell Transplantation', 'Cells, Cultured', 'Dependovirus', 'Female', 'Gene Transfer Techniques', 'Genes, Reporter', 'Genetic Vectors', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Knee Injuries', 'Mesenchymal Stem Cell Transplantation', 'Me... | 21,590,406 | [['B04.280.030'], ['B01.050'], ['A02.165', 'A10.165.382'], ['A02.165.407.150', 'A02.835.583.192'], ['E02.095.147.500', 'E04.936.225'], ['A11.251'], ['B04.280.580.650.170'], ['E05.393.350'], ['G05.360.340.024.340.435'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276', 'D12.776.467', 'D23... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thermophilic archaeal enzymes and applications in biocatalysis. | Thermophilic enzymes have advantages for their use in commercial applications and particularly for the production of chiral compounds to produce optically pure pharmaceuticals. They can be used as biocatalysts in the application of 'green chemistry'. The thermophilic archaea contain enzymes that have already been used ... | ['Aeropyrum', 'Alcohol Dehydrogenase', 'Amidohydrolases', 'Aminohydrolases', 'Archaea', 'Archaeal Proteins', 'Biocatalysis', 'Green Chemistry Technology', 'Hydrolases', 'Models, Molecular', 'Protein Conformation', 'Sulfolobus solfataricus', 'Thermococcus', 'Transaminases'] | 21,265,764 | [['B02.075.200.500.050'], ['D08.811.682.047.820.250'], ['D08.811.277.087'], ['D08.811.277.151'], ['B02'], ['D12.776.090'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['J01.897.360'], ['D08.811.277'], ['E05.599.595'], ['G02.111.570.820.709'], ['B02.075.725.725.725.800'], ['B02.200.825.800.800'], ['D08.811.913.477.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Erythrokeratodermia variabilis. | A 47-year-old woman presented with both transient, figurate, erythematous patches and fixed, hyperkeratotic plaques on the upper extremities. Her cutaneous disease began in childhood and affects numerous siblings and her daughter. Her clinical presentation, history, and histopathologic analysis were consistent with ery... | ['Connexins', 'Erythema', 'Female', 'Humans', 'Keratosis', 'Middle Aged', 'Mutation'] | 14,594,578 | [['D12.776.543.585.250'], ['C17.800.229', 'C23.888.885.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.428'], ['M01.060.116.630'], ['G05.365.590']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The impact of posttraumatic stress disorder on blood pressure and heart rate in a veteran population. | Hyperarousal is a hallmark of posttraumatic stress disorder (PTSD). PTSD has been associated with increased blood pressure (BP) and heart rate (HR) in veteran populations. We retrospectively identified male patients consulted to outpatient psychiatry at the Iowa City Veterans Affairs Healthcare System. Patients were di... | ['Adult', 'Arousal', 'Blood Pressure', 'Cardiovascular Diseases', 'Combat Disorders', 'Cross-Sectional Studies', 'Explosions', 'Heart Rate', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Stress Disorders, Post-Traumatic', 'United States', 'Veterans'] | 23,371,434 | [['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['F03.950.750.249'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.230.208'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pharmacokinetic interactions of the microsomal triglyceride transfer protein inhibitor, lomitapide, with drugs commonly used in the management of hypercholesterolemia. | STUDY OBJECTIVE: To characterize the effects of two doses (10 and 60 mg) of lomitapide—a microsomal triglyceride transfer protein inhibitor approved as adjunct treatment to lower low-density lipoprotein cholesterol levels in patients with homozygous familial hypercholesterolemia—on the pharmacokinetics of several lipid... | ['Adolescent', 'Adult', 'Aged', 'Anticholesteremic Agents', 'Benzimidazoles', 'Carrier Proteins', 'Disease Management', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Drug Therapy, Combination', 'Female', 'Humans', 'Hypercholesterolemia', 'Male', 'Middle Aged', 'Prospective Studies', 'Young Adult'] | 24,734,312 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D03.633.100.103'], ['D12.776.157'], ['N04.590.607'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Telephone line transmission of rectilinear radionuclide scans. Report of a pilot project. | The General Electric-Elscint system for telephone line transmission of rectillinear scans has been tested and with certain limitations found to be acceptable in terms of diagnostic accuracy for many scan procedures. The system tested had some logistic disadvantage requiring batch processing of the scans, and making qua... | ['Data Display', 'Humans', 'Radionuclide Imaging', 'Telephone', 'Videotape Recording'] | 838,758 | [['F02.784.412.221', 'L01.296'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.710', 'E01.370.384.730'], ['L01.178.847.698'], ['J01.897.280.500.846.734', 'J01.897.280.500.898.840', 'L01.178.590.875.840', 'L01.178.820.090.846.734', 'L01.178.820.090.898.840', 'L01.280.940.840', 'L01.280.960.880']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Two cases of mesothelial/monocytic incidental cardiac excrescences of the heart. | Two cases of mesothelial/monocytic incidental cardiac excrescences in a 66-year-old female and an 80-year-old male are presented. Lesions had solid and tubular pattern formations which were composed of two predominant cell types of histiocytoid cells and cuboidal cells arranged in strips. The histiocytoid cells were ro... | ['Aged', 'Aged, 80 and over', 'Antigens, CD', 'Antigens, Differentiation, Myelomonocytic', 'Biomarkers, Tumor', 'Epithelium', 'Female', 'Heart Diseases', 'Histiocytes', 'Humans', 'Hyperplasia', 'Iatrogenic Disease', 'Immunohistochemistry', 'Keratins', 'Leukocyte Common Antigens', 'Male', 'Monocytes', 'Myocardium'] | 9,736,413 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.900', 'D23.101.100.900'], ['D23.101.140'], ['A10.272'], ['C14.280'], ['A11.329.372.385', 'A11.627.482.385', 'A11.733.397.385', 'A15.382.670.522.385', 'A15.382.680.397.385'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Apatite-forming ability and mechanical properties of PTMO-modified CaO-SiO2 hybrids prepared by sol-gel processing: effect of CaO and PTMO contents. | Transparent monolithics of triethoxysilane end-capped poly(tetramethylene oxide) (Si-PTMO)-modified CaO-SiO2 hybrids were successfully synthesized by hydrolysis and polycondensation of Si-PTMO, tetraethoxysilane (TEOS) and calcium nitrate. As for the samples with varying (Ca(NO3)2)/(TEOS) molar ratios under constant ra... | ['Apatites', 'Biocompatible Materials', 'Body Fluids', 'Calcium Compounds', 'Gels', 'Humans', 'Materials Testing', 'Microscopy, Electron, Scanning', 'Oxides', 'Silicon Dioxide', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties', 'Tensile Strength'] | 12,069,346 | [['D01.029.260.700.675.374.075.025', 'D01.146.360.050', 'D01.578.122', 'D01.695.625.675.650.075.025'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A12.207'], ['D01.146'], ['D20.280.320', 'D26.255.165.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['E01.370.350.515.402.541', 'E05.595.402.5... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
In vitro activity of telithromycin against Haemophilus influenzae at epithelial lining fluid concentrations. | BACKGROUND: Haemophilus influenzae is one of the main aetiological agents of community-acquired respiratory tract infections. The primary aim of this study was to evaluate the antibacterial activity of telithromycin against H. influenzae clinical isolates showing different pattern of resistance in comparison with azith... | ['Anti-Bacterial Agents', 'Azithromycin', 'Carbon Dioxide', 'Clarithromycin', 'Haemophilus Infections', 'Haemophilus influenzae', 'Humans', 'Ketolides', 'Microbial Sensitivity Tests', 'Respiratory Tract Infections', 'Time Factors', 'beta-Lactamases'] | 18,230,154 | [['D27.505.954.122.085'], ['D02.540.576.500.992.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D02.540.576.500.992.100'], ['C01.150.252.400.700.433'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540.576.500.992.445'], ['E01.370.225.875.595'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Allelic variation in the cg2 gene does not correlate with chloroquine resistance among Indian Plasmodium falciparum isolates. | The cg2 gene of Plasmodium falciparum has been proposed to be associated with chloroquine resistance. Here we describe PCR amplification and sequencing of all the four repeat regions (kappa (kappa), gamma (gamma), psi (psi) and omega (omega)) of this gene, from Indian isolates. There were variant forms for each of thes... | ['Alleles', 'Amino Acid Sequence', 'Animals', 'Antimalarials', 'Base Sequence', 'Chloroquine', 'DNA, Protozoan', 'Drug Resistance', 'Genetic Variation', 'Humans', 'India', 'Malaria, Falciparum', 'Molecular Sequence Data', 'Plasmodium falciparum', 'Polymerase Chain Reaction', 'Protozoan Proteins', 'Sequence Homology, Am... | 11,730,794 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.122.250.100.085'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.633.100.810.050.180'], ['D13.444.308.442'], ['G07.690.773.984'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.25... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
[Effect of knocking down Piezo1 mechanically sensitive protein on migration of MC3T3-E1 osteoblast cells]. | Objective: To discuss the effect of Piezo1 mechanically sensitive protein in migration process of mouse MC3T3-E1 osteoblast cells.Methods: The 5th-10th generation mouse MC3T3-E1 osteoblasts were divided into Piezo1-small interfering RNA (siRNA) transfection group (group A), negative control group (group B), and blank c... | ['Animals', 'Cell Differentiation', 'Cell Movement', 'Ion Channels', 'Mice', 'Osteoblasts', 'Osteocalcin', 'RNA, Small Interfering', 'Transfection'] | 30,644,257 | [['B01.050'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.329.629'], ['D12.776.157.125.700'], ['D13.150.650.700', 'D13.444.735.150.700', 'D13.444.735.790.552.875'], ['E05.393.350.810', 'G05.728.860... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute peritonsillar abscess caused by Arcanobacterium haemolyticum. | A patient is reported with a peritonsillar abscess yielding Arcanobacterium haemolyticum. This appears to be only the fifth such case described in the medical literature and the first from Europe. The organism has been reported as an occasional cause of tonsillopharyngitis with rash, resembling infection with Streptoco... | ['Acute Disease', 'Adult', 'Female', 'Gram-Positive Asporogenous Rods', 'Gram-Positive Bacterial Infections', 'Humans', 'Peritonsillar Abscess'] | 1,479,262 | [['C23.550.291.125'], ['M01.060.116'], ['B03.510.460.400'], ['C01.150.252.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.561.750.500', 'C01.830.025.675', 'C07.550.781.750.500', 'C08.730.561.750.500', 'C09.775.649.750.500']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Kawasaki disease patients with six principal symptoms have a high risk of being a non-responder. | BACKGROUND: A diagnosis of Kawasaki disease (KD) is established using six principal symptoms. Because the principal symptoms are deeply connected with KD, it is thus important to investigate the usefulness of the principal symptoms for evaluating the disease severity of KD.METHODS: Patients with definite KD or suspicio... | ['Aspirin', 'Child, Preschool', 'Coronary Aneurysm', 'Coronary Vessels', 'Drug Therapy, Combination', 'Humans', 'Immunoglobulins', 'Immunoglobulins, Intravenous', 'Infant', 'Logistic Models', 'Mucocutaneous Lymph Node Syndrome', 'Multivariate Analysis', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Inde... | 22,115,193 | [['D02.455.426.559.389.657.410.595.176'], ['M01.060.406.448'], ['C14.280.647.250.250', 'C14.907.055.395', 'C14.907.585.250.250'], ['A07.015.114.269', 'A07.015.908.194'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['D12.776.124... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Water quality analysis of the commercial boreholes in Mubi Metropolis, Adamawa State, Nigeria: geographic information system approach. | It is observed that most of the commercial boreholes in Mubi Metropolis are located along River Yedzeram which is the main river that runs across the town. Unfortunately, due to the geographical location of the town in savanna region with minimal water supply, water related small scale industries such as sachet water, ... | ['Geographic Information Systems', 'Groundwater', 'Humans', 'Nigeria', 'Urban Population', 'Water Pollutants', 'Water Pollution', 'Water Quality'] | 23,120,934 | [['L01.313.500.750.300.314', 'L01.470.750.750.462'], ['G01.311.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.190.565'], ['N01.600.900'], ['D27.888.284.903'], ['N06.850.460.790'], ['N06.850.460.350.080.750', 'N06.850.460.790.730']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
The use of a sonicate preparation of Mycobacterium tuberculosis (new tuberculin) in the assessment of BCG vaccination. | Six hundred and sixty four children attending elementary schools in and around the town of Butajira in Shoa district of Ethiopia have been skin-tested with a sonicate tuberculin and the responses have been divided into two different types. One of these types is believed to indicate protective immunity and the other tis... | ['Adolescent', 'Adult', 'Age Factors', 'BCG Vaccine', 'Child', 'Developing Countries', 'Ethiopia', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Hypersensitivity, Delayed', 'Male', 'Time Factors', 'Tuberculin', 'Tuberculin Test', 'Tuberculosis, Pulmonary', 'Ultrasonics'] | 6,606,885 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D20.215.894.135.825.100'], ['M01.060.406'], ['I01.615.500.300'], ['Z01.058.290.120.310'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.418'], ['G01.910.857'], ['D23.050.161.845'], ['E01.370.225.812... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]... | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Carbohydrate-like composition of submicron atmospheric particles and their production from ocean bubble bursting. | Oceans cover over two-thirds of the Earth's surface, and the particles emitted to the atmosphere by waves breaking on sea surfaces provide an important contribution to the planetary albedo. During the International Chemistry Experiment in the Arctic LOwer Troposphere (ICEALOT) cruise on the R/V Knorr in March and April... | ['Aerosols', 'Alaska', 'Atmosphere', 'Carbohydrates', 'Hydroxyl Radical', 'North America', 'Oceans and Seas', 'Organic Chemicals', 'Pacific Ocean', 'Particle Size', 'Salts', 'Sodium', 'Spectroscopy, Fourier Transform Infrared', 'Wind'] | 20,080,571 | [['D20.280.055', 'D26.255.165.055'], ['Z01.107.567.875.580.100'], ['G16.500.275.063', 'N06.230.300.100'], ['D09'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['Z01.107.567'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['D02'], ['Z01.756.700'], ['G02.712'], ['D01.786'], ['D01.268.549.... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Structural basis for ligand selectivity of heteromeric olfactory cyclic nucleotide-gated channels. | In vertebrate olfactory receptors, cAMP produced by odorants opens cyclic nucleotide-gated (CNG) channels, which allow Ca(2+) entry and depolarization of the cell. These CNG channels are composed of alpha subunits and at least two types of beta subunits that are required for increased cAMP selectivity. We studied the m... | ['Animals', 'Binding Sites', 'Biophysical Phenomena', 'Biophysics', 'Female', 'In Vitro Techniques', 'Ion Channel Gating', 'Ion Channels', 'Ligands', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Nucleotides, Cyclic', 'Olfactory Receptor Neurons', 'Oocytes', 'Protein Structure, Quaternary', 'Rats', 'Recombinant P... | 10,777,729 | [['B01.050'], ['G02.111.570.120'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['E05.481'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D27.720.470.480'], ['E05.599.595'], ['E05.393.420.601.575'], ['D13.695.462'], ['A04.531.520.573.580', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of pulmonary regurgitation on distensibility and flow of the branch pulmonary arteries in tetralogy of Fallot. | Significant pulmonary regurgitation (PR) after repair of tetralogy of Fallot (TOF) may affect flow in the pulmonary artery (PA) side branches. We sought to assess flow changes and distensibility of the PA side branches in vivo and test correlation with the degree of PR and right-ventricular (RV) dilatation. Thirty pati... | ['Adolescent', 'Adult', 'Blood Flow Velocity', 'Case-Control Studies', 'Child', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Pulmonary Artery', 'Pulmonary Circulation', 'Pulmonary Valve Insufficiency', 'Tetralogy of Fallot', 'Treatment Outcome'] | 23,292,337 | [['M01.060.057'], ['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E01.370.350.825.500.510'], ['M01.060.116.630'], ['A07.015.114.715'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Screening of protein tyrosine kinases activated during neural induction in Xenopus. | We have screened Xenopus animal cap ectodermal cells during neural induction for protein kinases (PK) and protein tyrosine kinases (PTKs) after their renaturation in gels containing the polydispersed substrate poly(Glu, Tyr). Following guanidine hydrochloride denaturation, renaturation, and phosphorylation with [gamma-... | ['Animals', 'Autoradiography', 'Enzyme Activation', 'Nervous System', 'Protein-Tyrosine Kinases', 'Xenopus laevis'] | 8,660,535 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G02.111.263', 'G03.328'], ['A08'], ['D08.811.913.696.620.682.725'], ['B01.050.150.900.090.180.610.500.562']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suppression of tumor necrosis factor-á-induced nuclear factor êB activation and aromatase activity by capsaicin and its analog capsazepine. | Target-specific drugs, including natural products, offer promise for the amelioration of cancer and other human ailments. Capsaicin, the pungent ingredient present in chilies (Capsicum annuum L.), and capsazepine, a synthetic analog of capsaicin (collectively referred to as vanilloids), are known to possess a variety o... | ['Anticarcinogenic Agents', 'Aromatase', 'Capsaicin', 'Capsicum', 'Cell Line', 'Humans', 'Inhibitory Concentration 50', 'NF-kappa B', 'Plant Extracts', 'Transfection', 'Tumor Necrosis Factor-alpha'] | 21,663,483 | [['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D08.244.453.489.500', 'D08.244.453.915.099', 'D08.811.682.690.708.170.447.500', 'D08.811.682.690.708.170.915.099', 'D12.776.422.220.453.489.500', 'D12.776.422.220.453.915.099'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A method for noncontact measurement of corneal diameter in children. | PURPOSE: To evaluate a new method for measuring corneal diameter in children.DESIGN: Prospective, cross-sectional study.METHODS: With a digital camera set at maximum focal distance, the authors photographed 92 children twice, each with a paper ruler taped to his or her forehead. Images were opened on a personal compute... | ['Child', 'Child, Preschool', 'Cornea', 'Cross-Sectional Studies', 'Diagnostic Techniques, Ophthalmological', 'Hemangioma', 'Humans', 'Infant', 'Infant, Newborn', 'Lacrimal Duct Obstruction', 'Photography', 'Prospective Studies', 'Retinal Neoplasms', 'Strabismus'] | 17,601,441 | [['M01.060.406'], ['M01.060.406.448'], ['A09.371.060.217'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.380'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C11.496.456'], ['E01.370.350.600', 'E05.712'], ['E05.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Production of gender-specific morning salivary cortisol reference intervals using internationally accepted procedures. | BACKGROUND: Salivary cortisol concentrations correlate well with biologically active unbound free plasma cortisol concentrations. Despite its practical and analytical advantages, salivary cortisol measurement has been used mainly as a research tool rather than for the routine evaluation of adrenal function. This may be... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Female', 'Gender Identity', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Reference Values', 'Saliva', 'Sensitivity and Specificity', 'Sex Factors', 'Time Factors'] | 15,576,306 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.9... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
TGF-â/Smad3 inhibit vascular smooth muscle cell apoptosis through an autocrine signaling mechanism involving VEGF-A. | We have previously shown that in the presence of elevated Smad3, transforming growth factor-â (TGF-â) transforms from an inhibitor to a stimulant of vascular smooth muscle cell (SMC) proliferation and intimal hyperplasia (IH). Here we identify a novel mechanism through which TGF-â/Smad3 also exacerbates IH by inhibitin... | ['Animals', 'Apoptosis', 'Autocrine Communication', 'Cells, Cultured', 'Humans', 'Hyperplasia', 'Male', 'Myocytes, Smooth Muscle', 'Rats', 'Rats, Sprague-Dawley', 'Signal Transduction', 'Smad3 Protein', 'Transforming Growth Factor beta', 'Tunica Intima', 'Vascular Endothelial Growth Factor A'] | 25,010,983 | [['B01.050'], ['G04.146.954.035'], ['G04.085.100'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['A11.620.520'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.111.820', 'G04.835'], ['D12.644.360.024.334.500.300', 'D12.776.157.057.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum and urinary magnesium during treatment of patients with chronic congestive heart failure. | Electrolyte disturbances are common in patients with Congestive Heart Failure (CHF) especially during long-term treatments. Unlike potassium, little is known of how magnesium is affected in these patients. This study was carried out to determine the serum and urinary concentration of magnesium in patients with CHF who ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Angiotensin-Converting Enzyme Inhibitors', 'Cardiotonic Agents', 'Case-Control Studies', 'Digoxin', 'Diuretics', 'Female', 'Furosemide', 'Heart Failure', 'Humans', 'Lisinopril', 'Magnesium', 'Magnesium Deficiency', 'Male', 'Middle Aged', 'Severity of Illness Index',... | 11,714,011 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.389.745.085'], ['D27.505.954.411.222', 'D27.720.799.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688', 'D09.408.180.261.436... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An electrochemical biosensor for the detection of Pb2+ | We present a novel simple strategy for the detection of Pb2+ based on G-quadruplex DNA and gold nanoparticles. First, gold nanoparticles were chemically adsorbed onto the surface of a thiol-modified gold electrode. Subsequently, the substrate DNA1 was adsorbed onto the surfaces of the gold nanoparticles via thiol-gold ... | ['Biosensing Techniques', 'Cations, Divalent', 'DNA', 'Electrochemical Techniques', 'Electrodes', 'Environmental Monitoring', 'G-Quadruplexes', 'Gold', 'Lead', 'Limit of Detection', 'Metal Nanoparticles', 'Nucleic Acid Hybridization', 'Soil', 'Soil Pollutants', 'Water', 'Water Pollutants, Chemical'] | 29,959,487 | [['E05.601.043'], ['D01.248.497.300.333'], ['D13.444.308'], ['E05.301'], ['E07.305.250'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G02.111.570.820.486.550', 'G05.360.580.550'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D01.268.556.435', 'D01.552.544.435'], ['E05.318.740.872.374', 'N05.715.360.75... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Surface properties of fluoride treated hydroxyapatite as judged by interactions with albumin and lysozyme. | Hydroxyapatite treated with fluoride containing both alkali soluble fluoride (CaF2) and alkali stable fluoride (FAp) was shown to take up less albumin than hydroxyapatite but more lysozyme. The affinity of the adsorption of albumin to fluoride treated apatite was increased, whereas no difference was demonstrated in the... | ['Adsorption', 'Albumins', 'Chemical Phenomena', 'Chemistry, Physical', 'Durapatite', 'Fluorides', 'Hydroxyapatites', 'Muramidase', 'Surface Properties', 'Time Factors'] | 6,314,484 | [['G01.030', 'G02.020'], ['D12.776.034'], ['G02'], ['H01.181.529'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['D01.248.497.158.380', 'D01.303.350.300'], ['D01.029.260.700.675.374.075.025.300', 'D01.146.360.050.300', 'D01.578.12... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Stabilization of anthocyanin and skullcap flavone complexes--investigations with computer simulation and experimental methods. | We examined the stabilization of anthocyanins with flavones from the practical and theoretical perspective. The influence of addition of skullcap flavones, heating to 50 °C, and 12 day storage time (in the presence and absence of light) on the stability of anthocyanins in honeysuckle concentrates was investigated exper... | ['Anthocyanins', 'Computer Simulation', 'Flavones', 'Hot Temperature', 'Hydrophobic and Hydrophilic Interactions', 'Lonicera', 'Molecular Structure', 'Plant Extracts', 'Scutellaria baicalensis'] | 23,265,516 | [['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['L01.224.160'], ['D03.383.663.283.266.450.260', 'D03.633.100.150.266.450.260'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.4... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Role of light and heavy minerals on natural radioactivity level of high background radiation area, Kerala, India. | Natural radionuclides ((238)U, (232)Th and (40)K) concentrations and eight different radiological parameters have been analyzed for the beach sediments of Kerala with an aim of evaluating the radiation hazards. Activity concentrations ((238)U and (232)Th) and all the radiological parameters in most of the sites have hi... | ['Background Radiation', 'Cluster Analysis', 'Humans', 'India', 'Metals, Heavy', 'Minerals', 'Radiation Monitoring', 'Radioactive Pollutants', 'Radioisotopes', 'Spectroscopy, Fourier Transform Infrared'] | 24,361,519 | [['G01.750.750.115'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['D01.268.556', 'D01.552.544'], ['D01.578'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['D20.693'], ['D01.496.749'], ['E05.196.712.726.676.700',... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Decline in neurophysiological function after 7 years in an adolescent diabetic cohort and the role of aldose reductase gene polymorphisms. | OBJECTIVE: This 7-year longitudinal study examines the potential impact of aldose reductase gene (AKR1B1) polymorphisms on the decline of nerve function in an adolescent diabetic cohort.RESEARCH DESIGN AND METHODS: Patients with type 1 diabetes (n = 262) were assessed with three cardiovascular autonomic tests (heart ra... | ['Adolescent', 'Aldehyde Reductase', 'Alleles', 'Autonomic Nervous System', 'Diabetes Mellitus, Type 1', 'Dinucleotide Repeats', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Genotype', 'Heart Rate', 'Humans', 'Longitudinal Studies', 'Male', 'Polymorphism, Genetic', 'Reflex, Pupillary', 'Valsalva Ma... | 16,936,152 | [['M01.060.057'], ['D08.811.682.047.150.700.156.500', 'D08.811.682.047.820.284.500'], ['G05.360.340.024.340.030'], ['A08.800.050'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G02.111.570.080.708.800.500.150', 'G05.360.080.708.800.500.150', 'G05.360.340.024.850.500.150'], ['G05.330'], ['C23.550.291.687.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Improving quality and accessibility in our health care system: cost effective controls in a reformed system. | We need to examine the elements of health reform and to debate them based on what type of health care system we want in the future. If we continue down the current course, the numbers of uninsured will grow; benefit coverage will be reduced; increasing numbers of small employers will not be able to afford to buy covera... | ['Cost Control', 'Cost-Benefit Analysis', 'Delivery of Health Care', 'Health Care Costs', 'Health Care Rationing', 'Health Care Reform', 'Health Expenditures', 'Health Resources', 'Health Services Accessibility', 'Humans', 'Insurance Benefits', 'Insurance, Dental', 'Insurance, Health', 'Patient Participation', 'Quality... | 8,051,334 | [['N03.219.151.160'], ['N03.219.151.125'], ['N04.590.374', 'N05.300'], ['N03.219.151.400', 'N05.300.375'], ['I01.261.750.500', 'N03.349.270', 'N05.300.430.375'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['N03.219.151.450', 'N... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
An oscillation-based model for the neuronal basis of attention. | We propose a model for the neuronal implementation of selective visual attention based on the temporal structure of neuronal activity. In particular, we set out to explain the electrophysiological data from areas V4 and IT in monkey cortex of Moran and Desimone [(1985) Science, 229, 782-784] using the "temporal tagging... | ['Action Potentials', 'Animals', 'Attention', 'Computer Simulation', 'Geniculate Ganglion', 'Haplorhini', 'Neurons, Afferent', 'Visual Cortex'] | 8,296,473 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['F02.830.104.214'], ['L01.224.160'], ['A08.340.390.380', 'A08.800.350.380', 'A08.800.800.120.250.280'], ['B01.050.150.900.649.313.988.400'], ['A08.675.650', 'A11.671.650'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The Personal Acoustics Lab (PAL): a microcomputer-based system for digital signal acquisition, analysis, and synthesis. | A new, integrated digital signal processing (DSP) system, the Personal Acoustics Lab (PAL), is described. This microcomputer-based system is suitable for analogue signal digitization at rates from several samples per hour to 150,000 samples per second in 12- or 16-bit words. Data may be acquired on one to sixteen singl... | ['Animals', 'Biomedical Engineering', 'Computer Systems', 'Humans', 'Microcomputers', 'Signal Processing, Computer-Assisted', 'Speech', 'Speech Acoustics', 'Vocalization, Animal'] | 3,816,166 | [['B01.050'], ['H02.070', 'J01.293.140'], ['L01.224.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.260.550'], ['L01.224.800'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['G11.561.812.650', 'G11.561.820'], ['F01.145.113.055.800']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Secular change in body height and cephalic index of Croatian medical students (University of Rijeka). | An investigation of body height and cephalic measurements was performed among five groups of first-year medical students of the University of Rijeka School of Medicine (Rijeka, Croatia). Body height and different cephalic measurements showed normal distribution, both in male and female students. Differences between mea... | ['Adult', 'Analysis of Variance', 'Anthropometry', 'Body Height', 'Cephalometry', 'Croatia', 'Female', 'Humans', 'Male', 'Population Surveillance', 'Sex Distribution'] | 14,669,240 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['Z01.542.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The stapled continent ileocecal urinary reservoir in the surgical management of gynecologic malignancy. | Total cystectomy at the time of radical pelvic surgery for gynecologic malignancies is not uncommon. Many techniques have been developed for urinary diversion including the continent ileocecal urinary reservoir. Twenty-nine patients underwent construction of a continent ileocecal urinary reservoir during the reconstruc... | ['Adult', 'Aged', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Ileum', 'Middle Aged', 'Proctocolectomy, Restorative', 'Surgical Stapling', 'Urinary Reservoirs, Continent'] | 7,959,282 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.945.418', 'C13.351.937.418'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['M01.060.116.630'], ['E04.210.219.620', 'E04.210.895.500'], ['E04.987.775.800'], ['A10.850.750', 'E07.862.750']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Overuse injuries of the olecranon in young gymnasts. | We report overuse injuries in 14 elbows of ten ?lite young gymnasts. In 12 elbows of eight patients aged 11 to 15 years there was a spectrum of radiological abnormalities including widening of the olecranon physis and fragmentation of the epiphysis. The radiographs were compared with those of normal elbows matched for ... | ['Adolescent', 'Athletic Injuries', 'Child', 'Cumulative Trauma Disorders', 'Female', 'Follow-Up Studies', 'Fractures, Stress', 'Gymnastics', 'Humans', 'Inflammation', 'Male', 'Radiography', 'Time Factors', 'Ulna', 'Ulna Fractures'] | 1,544,975 | [['M01.060.057'], ['C26.115'], ['M01.060.406'], ['C26.844.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.437'], ['G11.427.410.698.277.156', 'I03.350.156', 'I03.450.642.845.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['E01.370.350.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A reversed Ebbinghaus-Titchener illusion in bantams (Gallus gallus domesticus). | A disk surrounded by smaller disks looks larger, and one surrounded by larger disks looks smaller than reality. This visual illusion, called the Ebbinghaus-Titchener illusion, remains one of the strongest and most robust illusions induced by contrast with the surrounding stimuli in humans. In the present study, we aske... | ['Animals', 'Chickens', 'Conditioning, Operant', 'Discrimination, Psychological', 'Female', 'Male', 'Optical Illusions', 'Pattern Recognition, Physiological', 'Photic Stimulation'] | 23,995,772 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['F02.463.425.179.509'], ['F02.463.593.257'], ['F02.463.593.446.659'], ['F02.463.593.524'], ['E05.723.729']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vision loss in older persons. | Family physicians have an essential role in assessing, identifying, treating, and preventing or delaying vision loss in the aging population. Approximately one in 28 U.S. adults older than 40 years is visually impaired. Vision loss is associated with depression, social isolation, falls, and medication errors, and it ca... | ['Aged', 'Aged, 80 and over', 'Amiodarone', 'Anti-Asthmatic Agents', 'Blindness', 'Cataract', 'Causality', 'Comorbidity', 'Diabetic Retinopathy', 'Geriatric Assessment', 'Glaucoma, Open-Angle', 'Humans', 'Macular Degeneration', 'Phosphodiesterase Inhibitors', 'Practice Guidelines as Topic', 'Refractive Errors', 'Vision... | 19,514,694 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D03.633.100.127.075'], ['D27.505.954.796.050'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['C11.510.245'], ['N05.715.350.200', 'N06.850.490.625'], ['N05.715.350.225', 'N06.850.490.687'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Biocomplexity in a highly migratory pelagic marine fish, Atlantic herring. | The existence of biologically differentiated populations has been credited with a major role in conferring sustainability and in buffering overall productivity of anadromous fish population complexes where evidence for spatial structure is uncontroversial. Here, we describe evidence of correlated genetic and life histo... | ['Animal Migration', 'Animals', 'Female', 'Fisheries', 'Fishes', 'Genetic Variation', 'Geography', 'Homing Behavior', 'Male', 'North Sea', 'Seasons', 'Sexual Behavior, Animal'] | 16,777,738 | [['F01.145.113.069.500'], ['B01.050'], ['J01.040.168.300', 'J03.540.280'], ['B01.050.150.900.493'], ['G05.365'], ['H01.277.500'], ['F01.145.113.646'], ['Z01.756.092.650'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['F01.145.113.252.748']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Work load management system ensures stable nurse-patient ratio. | The concept of adjusting work load to staffing is the reverse of most currently accepted practices. However, that is precisely how this management and measurement system works. Patient care units (PCU'S) are estimated for all incoming admissions, and patients are assigned to the units that have the lowest PCU count, th... | ['Efficiency', 'Hospital Bed Capacity, 100 to 299', 'North Carolina', 'Nursing Service, Hospital', 'Patient Care Planning', 'Personnel Management', 'Personnel Staffing and Scheduling', 'Time and Motion Studies'] | 624,541 | [['F02.784.692.351', 'N04.452.209'], ['N02.278.306.472.120'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['N02.278.216.500.968.489', 'N02.421.539.180', 'N04.452.442.452.422.489'], ['N04.590.233.624'], ['N04.452.677'], ['I03.946.225', 'N04.452.677.650'], ['F02.784.412.846.707', 'F02.784.692.746.707']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Serum tests for pancreatitis in patients with abdominal pain. | Though the serum total amylase test has been used for the diagnosis of pancreatitis for over 50 years, both its clinical sensitivity and specificity are far from perfect. We first present the results of serial serum total amylase, pancreatic isoamylase, lipase, and immunoreactive trypsin tests in nine patients during t... | ['Abdomen', 'Amylases', 'Blood Donors', 'Clinical Enzyme Tests', 'Evaluation Studies as Topic', 'Humans', 'Immunoassay', 'Isoamylase', 'Lipase', 'Pain', 'Pancreas', 'Pancreatitis', 'Reference Values', 'Trypsin'] | 2,580,501 | [['A01.923.047'], ['D08.811.277.450.066'], ['M01.898.313'], ['E01.370.225.124.200', 'E05.196.427.200', 'E05.200.124.200'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['D08.811.277.450.585'], ['D08.811.277.352.100.400'], ['C23.888.592.612', 'F02.830.8... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effect of different somatotypes on the intensity of changes of indices of height and body mass during early childhood]. | Anthropometric study of 1425 children of both sexes aged 4-7 years followed by somatodiagnostics according to R. N. Dorokhov method has revealed that at the age of 4 significant proportion of girls belonged to macrosomal type. In the age period of 5-7 years, most part of the children belonged to mesosomal type. However... | ['Anthropometry', 'Body Composition', 'Body Height', 'Body Weight', 'Child', 'Child, Preschool', 'Female', 'Growth', 'Humans', 'Male', 'Sex Factors', 'Somatotypes'] | 12,741,116 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A parsimonious approach to modeling animal movement data. | Animal tracking is a growing field in ecology and previous work has shown that simple speed filtering of tracking data is not sufficient and that improvement of tracking location estimates are possible. To date, this has required methods that are complicated and often time-consuming (state-space models), resulting in l... | ['Animals', 'Methods', 'Models, Biological', 'Movement', 'Seals, Earless'] | 19,262,755 | [['B01.050'], ['E05.581'], ['E05.599.395'], ['G07.568', 'G11.427.410'], ['B01.050.150.900.649.313.750.250.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An analytical derivative procedure for the calculation of vibrational Raman optical activity spectra. | We present an analytical time-dependent Hartree-Fock algorithm for the calculation of the derivatives of the electric dipole-magnetic dipole polarizability with respect to atomic Cartesian coordinates. Combined with analogous procedures to determine the derivatives of the electric dipole-electric dipole and electric di... | ['Algorithms', 'Computer Simulation', 'Electrons', 'Epoxy Compounds', 'Quantum Theory', 'Spectrum Analysis, Raman', 'Time Factors', 'Vibration'] | 18,052,417 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['G01.249.335', 'G01.358.500.750'], ['D02.355.291.411'], ['H01.671.579.800'], ['E05.196.822.860', 'E05.196.867.890'], ['G01.910.857'], ['G01.374.930']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice. | Perforin-mediated cytotoxicity is essential for clearance of primary LCMV infection. BALB/c-perforin-deficient (PKO) mice survived LCMV infection by deleting NP(118)-specific CD8(+) T cells whereas vaccination of PKO mice with Listeria expressing NP(118) generated a stable memory CD8(+) T cell population. However, >85%... | ['Animals', 'CD8-Positive T-Lymphocytes', 'Cytokines', 'Homeostasis', 'Immunophenotyping', 'Listeria monocytogenes', 'Lymphocytic Choriomeningitis', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Knockout', 'Nucleoproteins', 'Peptide Fragments', 'Perforin', 'Pore Forming Cytotoxic Proteins', 'Vaccinati... | 12,705,850 | [['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.410'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. | Talin (tln) binds and activates integrins to couple extracellular matrix-bound integrins to the cytoskeleton; however, its role in heart development is not well characterized. We identified the defective gene and the resulting cardiovascular phenotypes in zebrafish tln1(fl02k) mutants. The ethylnitrosourea-induced fl02... | ['Amino Acid Sequence', 'Animals', 'Endothelium, Vascular', 'Heart', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Integrin beta1', 'Mice', 'Molecular Sequence Data', 'Mutation', 'Sequence Homology, Amino Acid', 'Talin', 'Zebrafish'] | 26,310,270 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A07.015.700.500', 'A10.272.491.355'], ['A07.541'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408.200.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['G05.365.590'], ['G02.111.810.200',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Early Detection of Colorectal Cancer: a Multi-Center Pre-Clinical Case Cohort Study for Validation of a Combined DNA Stool Test. | BACKGROUND: Although colonoscopy-based screening has proven to be highly effective in detecting colorectal cancer (CRC), participation rates remain disappointing. Development of CRC is associated with a number of genetic or somatic mutations. New, non-invasive stool tests are currently being developed based on the dete... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Colonoscopy', 'Colorectal Neoplasms', 'DNA, Neoplasm', 'Early Detection of Cancer', 'Feces', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Mutation', 'Occult Blood', 'Proto-Oncogene Proteins B-raf', 'Proto-Oncogene Proteins p21(ras)', 'Sensitivit... | 30,336,540 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence and consequences of nocturnal hypoglycemia among conventionally treated children with diabetes mellitus. | To determine the prevalence and predictors of, and the glucose responses after, nocturnal hypoglycemia, we studied 135 pediatric patients with insulin-dependent diabetes mellitus on 388 nights. The frequencies of blood glucose values less than 60, 50, and 40 mg/dl (3.3, 2.8, and 2.2 mmol/L) at 2 AM were 14.4%, 7.0%, an... | ['Adolescent', 'Blood Glucose', 'Circadian Rhythm', 'Darkness', 'Diabetes Mellitus, Type 1', 'Eating', 'Energy Intake', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemia', 'Insulin', 'Prevalence', 'Probability', 'Sensitivity and Specificity', 'Time Factors'] | 2,184,211 | [['M01.060.057'], ['D09.947.875.359.448.500'], ['G07.180.562.190'], ['G01.590.540.233'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.650.240.340'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An atypical bladder diverticulum presented with recurrent peritonitis: case report. | Bladder diverticula develop from congenital detrusor muscle defect and frequently present with urinary tract infection, which occurs as a result of urinary stasis in the diverticula. Different clinical presentations, such as bladder outlet obstruction, cyanosis of the lower extremities, intestinal obstruction, ureteral... | ['Abdominal Pain', 'Child', 'Diagnosis, Differential', 'Diverticulum', 'Female', 'Humans', 'Peritonitis', 'Urinary Bladder Neck Obstruction', 'Vomiting'] | 21,935,839 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.406'], ['E01.171'], ['C06.405.205.282.750', 'C23.300.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.463.600', 'C06.844.640'], ['C12.777.767.700.962', 'C12.777.829.760', 'C13.351.968.767.700.850', 'C13.351.968.829.601'], ['C23.888.821.937']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Computer-aided design of a factor Xa inhibitor by using MCSS functionality maps and a CAVEAT linker search. | We have investigated a new approach to efficiently find a novel inhibitor against a serine protease (i.e. an activated coagulation factor X, FXa) by using de novo design programs and the X-ray crystal structure of the target enzyme. FXa is a coagulant enzyme that generates thrombin (a serine protease) and participates ... | ['Antithrombin III', 'Binding Sites', 'Computer Simulation', 'Crystallography, X-Ray', 'Factor Xa', 'Models, Molecular', 'Molecular Structure', 'Protein Conformation', 'Trypsin'] | 12,932,781 | [['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['G02.111.570.120'], ['L01.224.160'], ['E05.196.309.742.225'], ['D08.811.277.656.300.760.315', 'D08.811.277.656.959.350.315', 'D12.776.124.125.400.315', 'D23.119.400.315'], ['E05.599.595'], ['G02.111.57... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phenomenological subtypes of mania and their relationships with substance use disorders. | OBJECTIVE: The aim of the present study was to determine the distinct clusters of subtypes among patients with bipolar disorder (BD) and the relationship between the clinical features of BD patients, particularly substance use disorders (SUDs) and the clusters.METHOD: The present study initially assessed 96 inpatients ... | ['Adolescent', 'Adult', 'Aged', 'Bipolar Disorder', 'Cluster Analysis', 'Factor Analysis, Statistical', 'Humans', 'Inpatients', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Psychotic Disorders', 'Substance-Related Disorders', 'Suicide, Attempted', 'Young Adult'] | 25,560,193 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F03.084.500'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['M01.060.116.630'], ['F04.711.513.653'], ['F03... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Prototype formation from imaged, kinesthetically, and visually presented geometric figures. | The issue of prototype formation from simple geometric figures presented in various modes was studied in four conditions. Base figures and their exemplars were scaled in terms of their physical similarity, which was considered to reflect cognitive similarity. Geometric exemplars were visually presented, imaged by the s... | ['Discrimination Learning', 'Form Perception', 'Humans', 'Imagination', 'Kinesthesis', 'Orientation', 'Pattern Recognition, Visual'] | 528,968 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Experimental results on the recognition of embryos in human assisted reproduction. | The recognition of embryos suitable for transfer in human assisted reproduction is important, and there is evidence that the morphology of the cells may influence the results achievable. A procedure for this recognition problem has been formulated based on morphological attributes of the images of the embryos, and it i... | ['Adult', 'Algorithms', 'Case-Control Studies', 'Embryo Transfer', 'Embryo, Mammalian', 'Expert Testimony', 'Female', 'Humans', 'Pattern Recognition, Automated', 'Reproductive Techniques, Assisted', 'Single-Blind Method', 'Tissue Survival'] | 15,149,572 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.875.800.500', 'E05.820.800.500'], ['A16.254'], ['I01.880.604.583.232', 'N03.706.535.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.399.750'], ['E02.875.800', 'E05.820.800'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Vascular endothelial growth factor (VEGF) expression in the subacromial bursa is increased in patients with impingement syndrome. | Vascular endothelial growth factor (VEGF), which is known to be an angiogenetic factor, plays an important role in the inflammation of synovial tissue. To investigate the relationships between VEGF and clinical symptoms in rotator cuff disease, VEGF expression was examined using RT-PCR and immunohistochemical analysis ... | ['Acromion', 'Aged', 'Bursa, Synovial', 'DNA Primers', 'Endothelial Growth Factors', 'Humans', 'Immunohistochemistry', 'Lymphokines', 'Middle Aged', 'Pain Measurement', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Rotator Cuff', 'Rotator Cuff Injuries', 'Shoulder Impingement Syndrome', 'Shoulde... | 11,398,859 | [['A02.835.232.087.783.261'], ['M01.060.116.100'], ['A02.835.583.156'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.2... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Association between somatic cell count after first parturition and cumulative milk yield in dairy cows. | The aim was to assess the association between the somatic cell count of parity 1 cows between 5 and 30 days in milk (SCC1), and subsequent cumulative milk yield over approximately two years for cows in English and Welsh dairy herds. The dataset included records from 43,461 cows in 2111 herds, from 2004 to 2006. Cumulat... | ['Animals', 'Cattle', 'Cell Count', 'Dairying', 'Female', 'Lactation', 'Milk', 'Parity', 'Pregnancy', 'Time Factors'] | 23,920,363 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['J01.040.246'], ['G08.686.523', 'G08.686.702.500'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['G08.686.677', 'G08.686.784.769.472',... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Pregnant women's experiences, needs, and preferences regarding information about malformations detected by ultrasound scan. | OBJECTIVES: The aim of the study was to explore pregnant women's experiences of received information in relation to fetal malformation detected on ultrasound.METHOD: An exploratory descriptive design was used. Semi-structured interviews with women who continued their pregnancy and women who chose to terminate were audi... | ['Abortion, Eugenic', 'Adult', 'Congenital Abnormalities', 'Empathy', 'Female', 'Humans', 'Interviews as Topic', 'Midwifery', 'Needs Assessment', 'Patient Education as Topic', 'Patient Preference', 'Patient Satisfaction', 'Pregnancy', 'Pregnancy Trimester, Second', 'Pregnant Women', 'Professional-Patient Relations', 'U... | 22,578,754 | [['E04.520.050.050'], ['M01.060.116'], ['C16.131'], ['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['H02.478.676.416'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['I02.233.332.500', 'N02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and P... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
An active transport system in the blood-brain barrier may reduce levodopa availability. | Levodopa, the primary drug used to treat patients with Parkinson's disease, is transported into the brain by the facilitative amino acid transporter (L1). We present here an unanticipated discovery: levodopa may be pumped out of the brain by a Na(+)-dependent transport system that couples the naturally occurring Na(+) ... | ['Animals', 'Biological Transport, Active', 'Blood-Brain Barrier', 'Capillary Permeability', 'Cattle', 'Dopamine Agents', 'Dose-Response Relationship, Drug', 'Endothelial Cells', 'Extracellular Fluid', 'Isoleucine', 'Levodopa', 'Models, Biological', 'Sodium', 'Time Factors', 'Tritium'] | 15,925,365 | [['B01.050'], ['G03.143.310'], ['A07.035', 'A08.186.211.035'], ['G03.143.330', 'G09.330.165'], ['B01.050.150.900.649.313.500.380.271'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436.275'], ['A11.284.295.260', 'A12.207.270'], ['D12.125.070.577', 'D12.125.142.383'], ['D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Murine hematopoietic stem cell dormancy controlled by induction of a novel short form of PSF1 by histone deacetylase inhibitors. | Hematopoietic stem cells (HSCs) can survive long-term in a state of dormancy. Little is known about how histone deacetylase inhibitors (HDACi) affect HSC kinetics. Here, we use trichostatin A (TSA), a histone deacetylase inhibitor, to enforce histone acetylation and show that this suppresses cell cycle entry by dormant... | ['ATP Binding Cassette Transporter, Subfamily B, Member 2', 'ATP-Binding Cassette Transporters', 'Animals', 'Cell Cycle', 'Dose-Response Relationship, Drug', 'Female', 'Flow Cytometry', 'Hematopoietic Stem Cells', 'Histone Deacetylase Inhibitors', 'Hydroxamic Acids', 'Mice', 'Mice, Inbred C57BL', 'NIH 3T3 Cells', 'Stru... | 25,933,513 | [['D12.776.157.530.100.075.250', 'D12.776.157.530.450.074.500.500.250.250', 'D12.776.395.550.020.400.305', 'D12.776.543.550.192.400.305', 'D12.776.543.585.100.200.250', 'D12.776.543.585.450.074.500.500.250.250'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['B01.050'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Global proteomic analysis of brain tissues in transient ischemia brain damage in rats. | Ischemia-reperfusion injury resulting from arterial occlusion or hypotension in patients leads to tissue hypoxia with glucose deprivation, which causes endoplasmic reticulum (ER) stress and neuronal death. A proteomic approach was used to identify the differentially expressed proteins in the brain of rats following a g... | ['Animals', 'Apoptosis', 'Cell Line', 'Disease Models, Animal', 'Endoplasmic Reticulum Stress', 'Gene Expression Regulation', 'Ischemic Attack, Transient', 'Male', 'Neurons', 'Oxidative Stress', 'Proteomics', 'Rats', 'Rats, Sprague-Dawley'] | 26,016,499 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G04.434'], ['G05.308'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['A08.675', 'A11.671'], ['G03.673', 'G07.775.750'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Towards a HPC-oriented parallel implementation of a learning algorithm for bioinformatics applications. | BACKGROUND: The huge quantity of data produced in Biomedical research needs sophisticated algorithmic methodologies for its storage, analysis, and processing. High Performance Computing (HPC) appears as a magic bullet in this challenge. However, several hard to solve parallelization and load balancing problems arise in... | ['Algorithms', 'Animals', 'Computational Biology', 'Computing Methodologies', 'Databases, Nucleic Acid', 'Europe', 'Humans', 'Software'] | 25,077,818 | [['G17.035', 'L01.224.050'], ['B01.050'], ['H01.158.273.180', 'L01.313.124'], ['L01.224'], ['L01.313.500.750.300.188.400.300.500', 'L01.313.500.750.300.188.400.325.630', 'L01.470.750.750.300.500', 'L01.470.750.750.325.630'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner. | Recent studies have shown that the p300/CREB binding protein (CBP)-associated factor (PCAF) is involved in transcriptional activation. PCAF activity has been shown strongly associated with histone acetyltransferase (HAT) activity. In this report, we present evidence for a HAT-independent transcription function that is ... | ['Acetyltransferases', 'Binding Sites', 'CREB-Binding Protein', 'Cell Cycle Proteins', 'DNA, Viral', 'Gene Expression Regulation, Viral', 'Gene Products, tax', 'Histone Acetyltransferases', 'Human T-lymphotropic virus 1', 'Humans', 'Nuclear Proteins', 'Recombinant Fusion Proteins', 'Response Elements', 'Saccharomyces c... | 10,567,539 | [['D08.811.913.050.134'], ['G02.111.570.120'], ['D08.811.913.050.134.415.500.575.249', 'D12.776.930.680.300'], ['D12.776.167'], ['D13.444.308.568'], ['G05.308.385'], ['D12.776.624.664.520.750.480', 'D12.776.964.700.750.480', 'D12.776.964.775.750.480', 'D12.776.964.925.984.410'], ['D08.811.913.050.134.415.500'], ['B04.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myocardial 201Tl washout after combined dipyridamole submaximal exercise stress: reference values from different patient groups. | Dipyridamole stress is favorable in patients unable to exercise maximally for 201Tl myocardial scintigraphy. Aside from an analysis of uptake defects, proper washout analysis can be limited by heart rate variations when isolated dipyridamole stress is used. Heart rate standardized 201Tl washout kinetics after a combine... | ['Adult', 'Aged', 'Coronary Disease', 'Dipyridamole', 'Exercise Test', 'Female', 'Heart', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Radionuclide Imaging', 'Reference Values', 'Thallium Radioisotopes'] | 2,920,742 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.250', 'C14.907.585.250'], ['D03.383.742.175'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.710', 'E01.370.3... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gustatory perception and metabolic utilization of sugars by Myrmica rubra ant workers. | The suitability of various nectar and honeydew sugars as a food source for the polyphagous ant species M. rubra (L.) was studied. The sugars used included monosaccharides (fructose, glucose, galactose, mannose, rhamnose), disaccharides (sucrose, maltose, trehalose, melibiose, lactose) and trisaccharides (melizitose, ra... | ['Animals', 'Ants', 'Carbohydrate Metabolism', 'Feeding Behavior', 'Female', 'Flowers', 'Male', 'Plants, Edible', 'Taste'] | 12,695,902 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['G02.111.158', 'G03.191'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A18.024.249.500'], ['B01.650.510'], ['F02.830.816.724', 'G11.561.790.724']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.