Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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A prospective evaluation of occult disorders in obstructed defecation using the 'iceberg diagram'. | OBJECTIVE: Surgical treatment of constipation and obstructed defecation (OD) carries frequent recurrences, as OD is an 'iceberg syndrome' characterized by 'underwater rocks' or occult diseases which may affect the outcome of surgery. The aim of this study was to evaluate occult disorders in order to alert the clinician... | ['Adult', 'Aged', 'Anxiety Disorders', 'Constipation', 'Defecography', 'Fecal Impaction', 'Female', 'Humans', 'Male', 'Manometry', 'Middle Aged', 'Patient Selection', 'Prospective Studies', 'Rectal Prolapse', 'Rectocele', 'Severity of Illness Index'] | 17,032,326 | [['M01.060.116'], ['M01.060.116.100'], ['F03.080'], ['C23.888.821.150'], ['E01.370.350.700.715.250'], ['C06.405.469.531.424'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['M01.060.116.630'], ['E05.581.500.653', 'N04.590.731'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.45... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Treatment of perigraft seroma in expanded polytetrafluoroethylene grafts by sequential fibrin sealing of the outer graft surface. | BACKGROUND: The recommended standard for treatment of perigraft seroma (PS) is the graft removal and the reconstruction using an alternative prosthesis. We assumed that a fibrin sealing of the outer surface of expanded polytetrafluoroethylene (ePTFE) grafts would prevent leakage and used this technique in the treatment... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Chi-Square Distribution', 'Device Removal', 'Female', 'Fibrin Tissue Adhesive', 'Germany', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Polytetrafluoroethy... | 20,800,429 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.199'], ['D12.776.124.270.305'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Modulation of a neuronal network by electrical high frequency stimulation in striatal slices of the rat in vitro. | The effects of the GABA(A) receptor antagonist bicuculline, the D2-like receptor antagonist sulpiride and the D1-like receptor antagonist SCH-23390 on the electrical high frequency stimulation (HFS)-evoked gamma-aminobutyric acid (GABA) and dopamine (DA) release were measured from slices of the rat striatum by means of... | ['Animals', 'Corpus Striatum', 'Electric Stimulation', 'Female', 'In Vitro Techniques', 'Nerve Net', 'Rats', 'Rats, Wistar'] | 16,310,287 | [['B01.050'], ['A08.186.211.200.885.287.249.487'], ['E05.723.402'], ['E05.481'], ['A08.511'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developing a practice formulary as a byproduct of computer controlled repeat prescribing. | We use our office computer to record and issue repeat prescriptions. Each month we look at a printout to see how many times a drug has been prescribed, with the goal of limiting our practice formulary. We have reduced by more than 10% the range of drugs that we use in the practice and have the possibility of knowing do... | ['Computers', 'Drug Prescriptions', 'Family Practice', 'Formularies as Topic'] | 6,428,523 | [['L01.224.230.260'], ['E02.319.307', 'N02.421.668.778.500'], ['H02.403.340.500'], ['L01.178.682.192.836.535']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Comparing the anchorage effects of micro-implant and J hook on treating patients with maxillary protrusion]. | PURPOSE: To investigate the differences in anchorage effects between micro-implants and J hook in treating patients with Class II division 1 maxillary protrusion.METHODS: Thirty-one cases of adult patients with Class II division 1 maxillary protrusion were treated. They were divided into 2 groups depending on their sel... | ['Adult', 'Cephalometry', 'Humans', 'Incisor', 'Malocclusion, Angle Class II', 'Maxilla', 'Molar', 'Orthodontic Appliances'] | 26,598,202 | [['M01.060.116'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.860.425'], ['C07.793.494.630'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['A14.549.167.860.525'], ['E06.658.453']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence of tardive dyskinesia in a clinic population. | The reported prevalence of tardive dyskinesia (TD) widely ranges from 0.5% to 70%. This variability is probably due to many factors, including different patient characteristics, drug treatment exposures, and investigator biases. The aim of this study was to evaluate the prevalence, severity, and symptom type of TD in a... | ['Adult', 'Age Factors', 'Aged', 'Antipsychotic Agents', 'Arousal', 'Cross-Sectional Studies', 'Dose-Response Relationship, Drug', 'Dyskinesia, Drug-Induced', 'Female', 'Humans', 'Long-Term Care', 'Male', 'Middle Aged', 'Psychotic Disorders', 'Stereotyped Behavior'] | 2,860,658 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F02.830.104', 'G11.561.035'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.690.773.875', 'G07.690.936.500'],... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Laparoscopic clam shell partial fundoplication achieves effective reflux control with reduced postoperative dysphagia and gas bloating. | BACKGROUND: We describe a novel laparoscopic "clam shell" partial fundoplication, incorporating a modified Toupet with an anterior fundic flap for the management of medically recalcitrant gastroesophageal reflux disease. We hypothesize that this clam-shell-like mechanism allows a dynamic rather than rigid circumferenti... | ['Deglutition Disorders', 'Female', 'Flatulence', 'Fundoplication', 'Gastroesophageal Reflux', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies'] | 17,954,090 | [['C06.405.117.119', 'C09.775.174'], ['C23.888.821.360'], ['E04.210.390'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A strategy for improving and integrating biomedical ontologies. | The integration of biomedical terminologies is indispensable to the process of information integration. When terminologies are linked merely through the alignment of their leaf terms, however, differences in context and ontological structure are ignored. Making use of the SNAP and SPAN ontologies, we show how three ref... | ['Anatomy', 'Humans', 'Pathology', 'Physiology', 'Terminology as Topic', 'Vocabulary, Controlled'] | 16,779,118 | [['H01.158.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.650'], ['H01.158.782'], ['L01.559.598.400'], ['L01.453.245.945']] | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Diffusion kurtosis imaging for differentiating borderline from malignant epithelial ovarian tumors: A correlation with Ki-67 expression. | PURPOSE: To investigate the use of diffusion kurtosis imaging (DKI) in differentiating borderline from malignant epithelial ovarian tumors (MEOTs) and to correlate DKI parameters with Ki-67 expression.MATERIALS AND METHODS: Fifty-two consecutive patients with epithelial ovarian tumors (17 borderline epithelial ovarian ... | ['Adult', 'Aged', 'Carcinoma, Ovarian Epithelial', 'Diffusion Magnetic Resonance Imaging', 'Diffusion Tensor Imaging', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Immunohistochemistry', 'Ki-67 Antigen', 'Middle Aged', 'Neoplasms, Glandular and Epithelial', 'Observer Variation', 'Ovarian Neoplasms', 'Rep... | 28,295,854 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.295', 'C04.588.322.455.199', 'C13.351.500.056.630.705.350', 'C13.351.937.418.685.350', 'C19.344.410.199', 'C19.391.630.705.350'], ['E01.370.350.825.500.150'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['B01.050.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Measurements of transient membrane potential after current switch-off as a tool to study the electrochemical properties of supported thin nanoporous layers. | We have studied the potential of chronopotentiometry after current switch-off as a tool for electrochemical characterization of thin supported nanoporous layers. Within the scope of this technique, a thin supported electrochemically active layer is polarized by direct electric current until a steady state is reached. A... | ['Electrochemistry', 'Membrane Potentials', 'Membranes, Artificial', 'Models, Chemical', 'Nanostructures', 'Nanotechnology', 'Porosity'] | 16,851,912 | [['H01.181.529.307'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E05.599.495'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['G01.374.710']] | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Immunophenotypical characterization of inflammatory cellular infiltrates in tinea. | In order to elucidate the still poorly understood pathogenetic pathways of acute tinea, the inflammatory cellular infiltrates in this infection were analyzed. Lesional punch biopsies were cryostat-sectioned and stained with monoclonal antibodies for immunophenotypization of T cells, B cells, macrophages and activation ... | ['Acute Disease', 'Antibodies, Monoclonal', 'B-Lymphocytes', 'Humans', 'Immunoenzyme Techniques', 'Immunophenotyping', 'Lymphocyte Activation', 'Macrophages', 'T-Lymphocytes', 'Tinea'] | 1,361,279 | [['C23.550.291.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary docosahexaenoic acid affects stearic acid desaturation in spontaneously hypertensive rats. | Docosahexaenoic acid (DHA, 22:6n-3) is an n-3 polyunsaturated fatty acid which attenuates the development of hypertension in spontaneously hypertensive rats (SHR). The effects of DHA on delta-9-desaturase activity in hepatic microsomes and fatty acid composition were examined in young SHR. Two groups of SHR were fed ei... | ['Animals', 'Diet', 'Docosahexaenoic Acids', 'Fatty Acids', 'Male', 'Microsomes, Liver', 'Rats', 'Rats, Inbred SHR', 'Stearic Acids', 'Stearoyl-CoA Desaturase'] | 11,026,622 | [['B01.050'], ['G07.203.650.240'], ['D10.212.302.380.410.210', 'D10.251.355.337.250', 'D10.627.430.450.375'], ['D10.251'], ['A11.284.835.540.541'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.700.400.300'], ['D10.251.882'], ['D08.811.682.690.708.392.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fracture treatment for the multiply injured patient. | Multiply injured patients are benefited by an intradisciplinary approach to treatment. Consultants provide expertise in the treatment of particular injured systems. Resuscitation and diagnostic evaluation are life-saving priorities of treatment in the emergency room. Definitive surgical treatment of body cavity injury ... | ['Critical Care', 'Femoral Fractures', 'Forearm Injuries', 'Fracture Fixation', 'Fractures, Bone', 'Humans', 'Humeral Fractures', 'Monitoring, Physiologic', 'Orthopedic Fixation Devices', 'Pelvic Bones', 'Tibial Fractures', 'Wounds and Injuries'] | 3,819,400 | [['E02.760.190', 'N02.421.585.190'], ['C26.404.061', 'C26.558.276'], ['C26.088.268'], ['E04.555.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.088.390', 'C26.404.500'], ['E01.370.520'], ['E07.858.442.660', 'E07.858.690.725'], ['A02.835.232.043.825'], ['C26.404.875', 'C26.558.857'], ['C26']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. | BACKGROUND: The transcription factor STAT3 is a downstream target of the LIF signalling cascade. LIF signalling or activation is sufficient to maintain embryonic stem (ES) cells in an undifferentiated and pluripotent state. To further investigate the importance of STAT3 in the establishment of ES cells we have in a fir... | ['Animals', 'Blastocyst Inner Cell Mass', 'Cell Line', 'DNA-Binding Proteins', 'Embryonic Stem Cells', 'Gene Expression', 'Gene Expression Profiling', 'Homeodomain Proteins', 'Immunohistochemistry', 'In Situ Hybridization', 'Mice', 'Mice, Transgenic', 'Nanog Homeobox Protein', 'Oligonucleotide Array Sequence Analysis',... | 18,500,982 | [['B01.050'], ['A16.254.500.533'], ['A11.251.210'], ['D12.776.260'], ['A11.872.700.250'], ['G05.297'], ['E05.393.332'], ['D12.776.260.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Circulating microRNA is a biomarker of biliary atresia. | OBJECTIVE: The lack of reliable noninvasive diagnostic biomarkers of biliary atresia (BA) results in delayed diagnosis and worsened patient outcome. Circulating microRNAs (miRNAs) are a new class of noninvasive biomarkers with encouraging diagnostic utility.METHODS: We examined the ability of serum miRNAs to distinguis... | ['Animals', 'Biliary Atresia', 'Biomarkers', 'Cholestasis', 'Diagnosis, Differential', 'Humans', 'Hyperbilirubinemia', 'Infant', 'Mice', 'MicroRNAs'] | 22,732,895 | [['B01.050'], ['C06.130.120.123', 'C06.198.125', 'C16.131.314.125'], ['D23.101'], ['C06.130.120.135'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.429'], ['M01.060.703'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Evaluation of haemostasis and endothelial dysfunction characteristics in patient with community-acquired pneumonia]. | The article deals with a study of hemostasis (D-dimer soluble fibrin-monomer complex, time fibrin self-assemblance, antitrombin III, fibrinogen), endothelial dysfunction (f. Willebrand and activity of plasminogen activators inhibitor type 1) and CRP in 61 patients with CAP in the day of admission and before discharge f... | ['C-Reactive Protein', 'Community-Acquired Infections', 'Endothelium, Vascular', 'Fibrin Fibrinogen Degradation Products', 'Hemostasis', 'Humans', 'Pneumonia, Bacterial', 'Predictive Value of Tests', 'Severity of Illness Index'] | 24,749,306 | [['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C01.234'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.776.124.270.300', 'D12.776.811.300.290'], ['G09.188.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.620', 'C01.748.610.540', 'C08.381.677.540', 'C08.730.610.540'], ['E05.3... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Acute subdural hematoma secondary to cerebrospinal fluid drainage during thoracic endovascular aortic repair (TEVAR): A case report]. | We report a case of acute subdural hematoma which occurred following cerebrospinal fluid (CSF) drainage during thoracic endovascular aortic repair (TEVAR) surgery. A 63-year-old woman was scheduled to receive TEVAR for thoracic-abdominal aneurysm extending from the descending aorta (T10) to 15 mm above the celiac trunk... | ['Aorta, Thoracic', 'Aortic Aneurysm, Thoracic', 'Celiac Artery', 'Cerebrospinal Fluid', 'Decompression, Surgical', 'Drainage', 'Endovascular Procedures', 'Female', 'Hematoma, Subdural, Acute', 'Humans', 'Intraoperative Complications', 'Middle Aged', 'Stents'] | 22,256,585 | [['A07.015.114.056.372'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['A07.015.114.207'], ['A12.207.270.210'], ['E04.188'], ['E02.309', 'E04.237'], ['E04.100.814.529', 'E04.502.382'], ['C10.228.140.300.535.450.400.050', 'C10.900.300.837.600.050', 'C14.907.253.573.400.450.050', 'C23.550.414.838.700.100', 'C23.550.4... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mid-arm lymph nodes dissection for melanoma. | An interval node in the upper limb termed the mid-arm node was recently identified. However, its surgical anatomy remains unclear. We report a patient with metastatic melanoma of the mid-arm node and the epitrochlear node at 10 years after removal of the primary tumour from the forearm and therapeutic axillary lymph no... | ['Diagnostic Imaging', 'Forearm', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Lymphatic Vessels', 'Male', 'Melanoma', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Skin Neoplasms'] | 20,227,935 | [['E01.370.350'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['C04.697.650.560', 'C23.550.727.650.560'], ['A15.382.520.301'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['C04.588.805', 'C17.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Detection of Neospora caninum in an aborted goat foetus. | In Italy Neospora caninum has been reported in cattle, in buffaloes and in dogs. No data are available about the infection in sheep and goats. In this paper, the authors report the detection of protozoan cysts, identified as N. caninum by PCR, in the brain of an aborted goat foetus. | ['Aborted Fetus', 'Abortion, Veterinary', 'Animals', 'Brain', 'Coccidiosis', 'DNA, Protozoan', 'Female', 'Goat Diseases', 'Goats', 'Neospora', 'Polymerase Chain Reaction', 'Pregnancy', 'RNA, Ribosomal, 18S'] | 15,325,053 | [['A16.378.099'], ['C13.703.039.422', 'C22.021'], ['B01.050'], ['A08.186.211'], ['C01.610.752.250'], ['D13.444.308.442'], ['C22.405'], ['B01.050.150.900.649.313.500.380.513'], ['B01.043.075.189.250.750.550'], ['E05.393.620.500'], ['G08.686.784.769'], ['D13.444.735.686.675']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The prevalence and perceived aetiology of male sexual problems in a non-clinical sample. | One hundred and nine men (38 per cent single, 48 per cent married) participated in a survey of the prevalence of erectile and ejaculatory difficulty in a non-clinical sample. Perceived aetiology of erectile difficulty was also investigated. Twenty-three per cent of the sample were currently experiencing sexual problems... | ['Adolescent', 'Adult', 'Aged', 'Communication', 'Ejaculation', 'Erectile Dysfunction', 'Extramarital Relations', 'Humans', 'Male', 'Middle Aged', 'Penile Erection', 'Personal Satisfaction', 'United Kingdom'] | 3,801,344 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.209', 'L01.143'], ['G08.686.784.084'], ['C12.294.644.486', 'F03.835.400'], ['F01.145.802.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.784.717'], ['F01.145.677'], ['Z01.542.363']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Prevalence of hyperinsulinaemia in patients with high blood pressure. | A total of 41 patients with hypertension were identified in a survey of 732 healthy factory workers. Twenty-three of these individuals were receiving antihypertensive medication, whereas 18 cases were newly discovered. Plasma glucose and insulin responses to oral glucose and fasting plasma triglyceride (TG), cholestero... | ['Blood Glucose', 'Cholesterol', 'Female', 'Glucose Tolerance Test', 'Humans', 'Hyperinsulinism', 'Hypertension', 'Hypertriglyceridemia', 'Insulin', 'Male', 'Middle Aged', 'Prevalence'] | 1,556,520 | [['D09.947.875.359.448.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968'], ['C14.907.489'], ['C18.452.584.500.500.851'], ['D06.472.699.587.200.500.62... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of risk factors on peripheral and cerebrovascular disease in men with coronary artery disease, low high-density lipoprotein cholesterol levels, and desirable low-density lipoprotein cholesterol levels. HIT Investigators. Department of Veterans Affairs HDL Intervention Trial. | BACKGROUND: The Veterans Administration-HDL Intervention Trial is an ongoing, 20-center, randomized, double-blind, placebo-controlled study aiming to assess the effect of gemfibrozil-improved low high-density lipoprotein cholesterol levels on cardiovascular morbidity and mortality rates.METHODS AND RESULTS: Eligible pa... | ['Aged', 'Cerebrovascular Disorders', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Coronary Disease', 'Diabetes Complications', 'Double-Blind Method', 'Hospitals, Veterans', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Peripheral Vascular Diseases', 'Risk Factors', 'Smoking', 'Surveys and Questionnaires', 'United Stat... | 9,778,079 | [['M01.060.116.100'], ['C10.228.140.300', 'C14.907.253'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['C14.280.647.250', 'C14.907.585.250'], ['C19.246.099'], ['E05.318... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Postmortem delay has minimal effect on brain RNA integrity. | The Bryan Alzheimer Disease Research Center obtains postmortem human brain tissue from patients with Alzheimer disease (AD) and cognitively normal control subjects for molecular and genetic research programs. A growing body of research suggests that variations in gene transcript levels may contribute to the onset and p... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Brain', 'Female', 'Gene Expression Regulation', 'Humans', 'Male', 'Middle Aged', 'Nerve Tissue Proteins', 'Postmortem Changes', 'RNA', 'Reverse Transcriptase Polymerase Chain Reaction', 'Specimen Handling'] | 18,090,918 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.631'], ['C23.550.260.224.617'], ['D13.444.735'], ['E05.393.620.500.725'], ['E01.370.225.998', 'E05.2... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sequence-specific interactions of the tight-binding I12-X86 lac repressor with non-operator DNA. | The tight-binding I12-X86 lac repressor binds to non-operator DNA in a sequence-specific fashion. Using the DNA of the E. coli I gene we have investigated these sequence-specific interactions and compared them to the operator binding of wild-type repressor. The specific, non-operator DNA interactions are sensitive to t... | ['Autoradiography', 'Base Sequence', 'DNA, Bacterial', 'Escherichia coli', 'Lac Operon', 'Repressor Proteins', 'Transcription Factors'] | 7,003,550 | [['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.686.545', 'G05.360.340.358.207.500.545'], ['D12.776.260.703', 'D12.776.930.780'], ['D12.776.930']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Synthesis and biological evaluation of a focused library of beauveriolides. | Fungal beauveriolide III (1b), discovered as an inhibitor of lipid droplet accumulation in mouse macrophages and showing antiatherogenic activity in mouse model, consists of l-Phe, l-Ala, d-allo-Ile, and (3S, 4S)-3-hydroxy-4-methyloctanoic acid moieties. A combinatorial library of beauveriolide analogues focusing on l-... | ['Alanine', 'Amino Acids', 'Animals', 'Atherosclerosis', 'Combinatorial Chemistry Techniques', 'Depsipeptides', 'Disease Models, Animal', 'Isoleucine', 'Lipid Metabolism', 'Macrophages', 'Mice', 'Molecular Structure', 'Sterol O-Acyltransferase', 'Structure-Activity Relationship'] | 18,620,856 | [['D12.125.042'], ['D12.125'], ['B01.050'], ['C14.907.137.126.307'], ['E05.197.312', 'J01.897.836.249.249'], ['D04.345.566.297', 'D12.644.641.297'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.125.070.577', 'D12.125.142.383'], ['G03.458'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Metachromatic leukodystrophy. Report of siblings with the juvenile type of metachromatic leukodystrophy. | Two sisters with juvenile metachromatic leukodystrophy are described. The patients were 17 and 20 years old. The younger sister died and an autopsy was performed. The elder sister keeps alive. A sural nerve biopsy of both cases revealed an accumulation of metachromatic lipid granules in the Schwann cells and macrophage... | ['Adolescent', 'Adult', 'Brain', 'Brain Chemistry', 'Female', 'Histocytochemistry', 'Humans', 'Immunohistochemistry', 'Leukodystrophy, Metachromatic', 'Lipids', 'Microscopy, Electron', 'Microscopy, Fluorescence', 'Sural Nerve'] | 3,188,912 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
A sleep/wake circuit controls isoflurane sensitivity in Drosophila. | General anesthesia remains a mysterious phenomenon, even though a number of compelling target proteins and processes have been proposed [1]. General anesthetics such as isoflurane abolish behavioral responsiveness in all animals, and in the mammalian brain, these diverse compounds probably achieve this in part by targe... | ['Anesthesia', 'Animals', 'Capsaicin', 'Dopamine', 'Dopaminergic Neurons', 'Dose-Response Relationship, Drug', 'Drosophila Proteins', 'Drosophila melanogaster', 'Drug Resistance', 'Female', 'Isoflurane', 'Locomotion', 'Neuroimaging', 'Neuromuscular Junction', 'Sleep', 'Syntaxin 1', 'Transcription Factors', 'Wakefulness... | 23,499,534 | [['E03.155'], ['B01.050'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['A08.675.278', 'A11.671.270'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.093... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wireless impedance measurements for monitoring peripheral vascular disease. | Wireless microdevices powered by ultrasound energy have been fabricated to measure and telemeter tissue impedance spectrums for applications in peripheral vascular disease monitoring. The system is characterized by simplicity of the implant consisting of only two electrical components. Ex vivo testing shows the potenti... | ['Dielectric Spectroscopy', 'Electrical Equipment and Supplies', 'Electrodes, Implanted', 'Microtechnology', 'Peripheral Vascular Diseases', 'Telemetry', 'Ultrasonics', 'Wireless Technology'] | 25,571,591 | [['E05.196.867.335'], ['E07.305'], ['E07.305.250.319', 'E07.695.202'], ['H01.570', 'J01.897.520.500'], ['C14.907.617'], ['E01.370.520.750', 'E05.925', 'L01.178.847.675'], ['H01.671.031.849'], ['L01.178.847.950']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Information Science [L]'] | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Infectious episodes in severely granulocytopenic patients. | In a prospective study, 40 episodes of granulocytopenia (granulocytes less than 500/mm3) in 34 patients were analyzed. During 52.5% of these episodes there was proven infection; these infections were present for only 24.4% of the 1,435 granulocytopenic days. The risk of infection and mortality were closely linked with ... | ['Adult', 'Agranulocytosis', 'Anti-Bacterial Agents', 'Bacterial Infections', 'Granulocytes', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies'] | 511,334 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fast and accurate average genome size and 16S rRNA gene average copy number computation in metagenomic data. | BACKGROUND: Metagenomics caused a quantum leap in microbial ecology. However, the inherent size and complexity of metagenomic data limit its interpretation. The quantification of metagenomic traits in metagenomic analysis workflows has the potential to improve the exploitation of metagenomic data. Metagenomic traits ar... | ['Benchmarking', 'DNA Copy Number Variations', 'Databases, Genetic', 'Gene Dosage', 'Genome Size', 'Metagenome', 'Metagenomics', 'Oceans and Seas', 'RNA, Ribosomal, 16S', 'Time Factors'] | 31,488,068 | [['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['G05.365.795.297.500'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.380.350'], ['G05.360.340.037'], ['G05.360.340.550'], ['H01.158.273.343.350.261'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.7... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Chloroplast biogenesis 88. Protochlorophyllide b occurs in green but not in etiolated plants. | It has recently been reported that protochlorophyllide (Pchlide) b is an abundant pigment in barley etioplasts but is rather unstable, as it is rapidly converted to Pchlide a by 7-formyl reductase during pigment extraction with conventional 80% acetone (Reinbothe, S., Pollmann, S., and Reinbothe, C. (2003) J. Biol. Che... | ['Acetone', 'Chlorophyll', 'Chloroplasts', 'Diethyl Pyrocarbonate', 'Hordeum', 'Light', 'Photobiology', 'Pigments, Biological', 'Plant Leaves', 'Plant Physiological Phenomena', 'Plant Proteins', 'Plastids', 'Protochlorophyllide', 'Spectrometry, Fluorescence'] | 14,594,820 | [['D02.522.064'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['A11.284.430.214.190.875.700.140'], ['D02.241.081.420.750.250'], ['B01.650.940.800.575.912.250.822.481'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['H01.158.273.738'], ['D23.767'], ['A18.024.81... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantifying the dynamics of coupled networks of switches and oscillators. | Complex network dynamics have been analyzed with models of systems of coupled switches or systems of coupled oscillators. However, many complex systems are composed of components with diverse dynamics whose interactions drive the system's evolution. We, therefore, introduce a new modeling framework that describes the d... | ['Cell Cycle', 'Computer Simulation', 'Models, Biological', 'Saccharomyces cerevisiae'] | 22,242,172 | [['G04.144'], ['L01.224.160'], ['E05.599.395'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The dorsoproximal-dorsodistal projection of the distal carpal bones in horses: an evaluation of different beam-cassette angles. | To estimate the extent of the third carpal bone (C3) visible for evaluation in the dorsoproximal-dorsodistal oblique projection of the distal row of carpal bones, 13 forelimbs collected at post mortem from 7 horses were examined radiographically. The limbs were frozen with the carpal joints flexed then radiographed usi... | ['Analysis of Variance', 'Animals', 'Carpal Bones', 'Female', 'Horse Diseases', 'Horses', 'Male', 'Radiography', 'Sclerosis'] | 10,528,842 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A02.835.232.087.319.150'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['E01.370.350.700'], ['C23.550.823']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dynamic assessment of cognitive and cardiovascular performance in the elderly. | Dynamic measures of cardiovascular and cognitive performance have been used as a preliminary step toward developing predictors of decline in functional performance in older persons. Both batteries use multiple measures to examine the cooperativity of various aspects of performance, and both examine the subject's respon... | ['Aged', 'Blood Pressure', 'Cognition', 'Female', 'Hemodynamics', 'Humans', 'Language Tests', 'Male', 'Memory', 'Middle Aged', 'Monitoring, Physiologic', 'Neuropsychological Tests', 'Reaction Time', 'Visual Perception'] | 3,744,772 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['F02.463.188'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['F02.463.425.540'], ['M01.060.116.630'], ['E01.370.520'], ['F04.711.513'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.59... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Macrophage colony-stimulating factor drives cord blood monocyte differentiation into IL-10(high)IL-12absent dendritic cells with tolerogenic potential. | Immature dendritic cells (DCs) induce tolerance and mature DCs induce inflammatory immune responses. However, the likelihood of maturation of immature DCs in vivo limits its potential application for suppression of unwanted immune reactions in vivo. The aim of this study was to generate DCs with anti-inflammatory prope... | ['CD4-Positive T-Lymphocytes', 'Cell Differentiation', 'Cell Proliferation', 'Dendritic Cells', 'Drug Synergism', 'Fetal Blood', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Humans', 'Immune Tolerance', 'In Vitro Techniques', 'Infant, Newborn', 'Interleukin-10', 'Interleukin-12', 'Interleukin-4', 'Isoantigens',... | 15,814,695 | [['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['G07.690.773.968.477'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['D12.644.276.374.410... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gene transfer by naked DNA into adult mouse brain. | Nonviral gene transfer into the central nervous system could provide a basis for therapeutic uses and fundamental research. We show that naked DNA injected intracerebrally into the mouse brain can provide expression of a reporter protein. Expression is dose dependent, being maximal for 150 mu g DNA injected. We observe... | ['Animals', 'Brain', 'DNA', 'Female', 'Gene Transfer Techniques', 'Genetic Therapy', 'Lipopolysaccharides', 'Luciferases', 'Mice'] | 9,156,801 | [['B01.050'], ['A08.186.211'], ['D13.444.308'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['D08.811.682.517', 'D12.776.532.510'], ['B01.050.150.900.649.313.992.635.505.500']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modelling correlated data: Multilevel models and generalized estimating equations and their use with data from research in developmental disabilities. | BACKGROUND: The use of Multilevel Models (MLM) and Generalized Estimating Equations (GEE) for analysing clustered data in the field of intellectual and developmental disability (IDD) research is still limited.METHOD: We present some important features of MLMs and GEEs: main function, assumptions, model specification an... | ['Cluster Analysis', 'Computer Simulation', 'Data Interpretation, Statistical', 'Developmental Disabilities', 'Humans', 'Intellectual Disability', 'Latent Class Analysis', 'Models, Statistical', 'Multilevel Analysis', 'Research Design'] | 29,786,528 | [['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['F03.625.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Zika virus damages the human placental barrier and presents marked fetal neurotropism. | An unusually high incidence of microcephaly in newborns has recently been observed in Brazil. There is a temporal association between the increase in cases of microcephaly and the Zika virus (ZIKV) epidemic. Viral RNA has been detected in amniotic fluid samples, placental tissues and newborn and fetal brain tissues. Ho... | ['Adult', 'Amniotic Fluid', 'Brain', 'Female', 'Humans', 'Immunohistochemistry', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Male', 'Microcephaly', 'Placenta', 'Pregnancy', 'RNA, Viral', 'Viral Tropism', 'Zika Virus', 'Zika Virus Infection'] | 27,143,490 | [['M01.060.116'], ['A12.098', 'A16.378.149'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.51... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Reduction of matrix interferences by the combination of chaotropic salt and DMSO in a broadly applicable target-based ELISA for pharmacokinetic studies of therapeutic monoclonal antibodies. | Use of a synergistic effect of DMSO together with a chaotropic salt (NaSCN or MgCl2) allowed to drastically reduce matrix interferences in an ELISA for therapeutic monoclonal antibodies. Optimum combinations were found to be 0.4 M NaSCN together with 10.0% DMSO, and 1.0 M MgCl2 with 15.0% DMSO. At this optimum combinat... | ['Animals', 'Antibodies, Monoclonal', 'Biotin', 'Chemistry, Pharmaceutical', 'Dimethyl Sulfoxide', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Macaca fascicularis', 'Rats', 'Recombinant Proteins', 'Reproducibility of Results', 'Salts', 'Solvents', 'Technology, Pharmaceutical'] | 19,608,373 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D03.383.129.308.080', 'D08.211.096'], ['H01.158.703.007', 'H01.181.466'], ['D02.886.640.150'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Distal locking using an electromagnetic field-guided computer-based real-time system for orthopaedic trauma patients. | OBJECTIVES: To compare the efficacy of distal interlocking during intramedullary nailing using a freehand technique versus an electromagnetic field real-time system (EFRTS).DESIGN: A prospective, randomized controlled trial.SETTING: Level I academic trauma center.PATIENTS/PARTICIPANTS: Patients older than 18 years who ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Computer Systems', 'Electromagnetic Fields', 'Equipment Design', 'Equipment Failure Analysis', 'Femoral Fractures', 'Fracture Fixation, Intramedullary', 'Humans', 'Middle Aged', 'Operative Time', 'Prospective Studies', 'Surgery, Computer-Assisted', 'Tibial Fractures... | 23,429,175 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['L01.224.230'], ['G01.358.500.260', 'G01.358.750.500'], ['E05.320'], ['E05.325.192'], ['C26.404.061', 'C26.558.276'], ['E04.555.300.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.614.374.500', 'N02.... | ['Named Groups [M]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Growth-factor-dependent mitogenesis requires two distinct phases of signalling. | Prolonged and continuous exposure to growth factors is required to commit cells to the cell cycle. Here we show that the prolonged requirement for growth factor can be replaced with two short pulses of mitogen. The first pulse of growth factor moves the cell through the initial segment of the G0 to S interval. This ini... | ['3T3 Cells', 'Animals', 'Cell Cycle', 'Cell Cycle Proteins', 'Culture Media, Serum-Free', 'Immunoblotting', 'Kinetics', 'MAP Kinase Kinase 1', 'Mice', 'Mitogen-Activated Protein Kinase Kinases', 'Phosphatidylinositol 3-Kinases', 'Platelet-Derived Growth Factor', 'Protein-Serine-Threonine Kinases', 'Proto-Oncogene Prot... | 11,175,749 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['G04.144'], ['D12.776.167'], ['D27.720.470.305.255', 'E07.206.255'], ['E05.478.566.320', 'E05.601.470.320'], ['G01.374.661', 'G02.111.490'], ['D08.811.913.696.620.682.700.565.100', 'D08.811.913.696.620.682.725.200.100', 'D12.644.360.440.100', 'D12.776.476.440.100']... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-invasive analysis of myoblast transplants in rodent cardiac muscle. | BACKGROUND: Magnetic resonance imaging (MRI) of magnetically labeled stem cells is a non-invasive approach that can provide images with high spatial resolution. We evaluated the ability of a commercially available, Food and Drug Administration (FDA) approved contrast agent to allow the monitoring of myoblast transplant... | ['Animals', 'Cell Differentiation', 'Cell Movement', 'Cell Survival', 'Cells, Cultured', 'Contrast Media', 'Female', 'Ferrosoferric Oxide', 'Graft Survival', 'Imaging, Three-Dimensional', 'Iron', 'Magnetic Resonance Imaging', 'Muscle Fibers, Skeletal', 'Myoblasts, Cardiac', 'Myocardium', 'Oxides', 'Polylysine', 'Rats',... | 15,856,647 | [['B01.050'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['G04.346'], ['A11.251'], ['D27.505.259.500', 'D27.720.259'], ['D01.490.100.375', 'D01.490.200.350', 'D01.578.285'], ['G12.875.545.340'], ['E01.370.350.400', 'L01.224.308.410'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['E01.370.350.825.500'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Interactions between the oocyte and cumulus cells in the ovary of the B6.Y(TIR) sex-reversed female mouse. | The XY (B6.Y(TIR)) sex-reversed female mouse is infertile, primarily because of the early death of its embryos. We have previously determined that the XY oocyte itself, not the surrounding somatic cells, is responsible for its failure in postfertilization development. In the present study, we assessed the ability of th... | ['Animals', 'Cell Communication', 'Cell Differentiation', 'Chimera', 'Disorders of Sex Development', 'Estradiol', 'Female', 'Genotype', 'Granulosa Cells', 'Male', 'Mice', 'Mice, Mutant Strains', 'Microscopy, Electron', 'Oocytes', 'Ovary', 'Progesterone', 'Sex Differentiation', 'Y Chromosome'] | 9,283,002 | [['B01.050'], ['G04.085'], ['G04.152'], ['B05.200'], ['C12.706.316', 'C13.351.875.253', 'C16.131.939.316', 'C19.391.119'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G05.380'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812', 'A11.436.329'], ['B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Knowledge, health beliefs and health-related behaviours of first-degree relatives of women suffering from osteoporosis in Taiwan: a questionnaire survey. | BACKGROUND: No previous study has examined knowledge, health beliefs and health-related behaviours in first-degree relatives (FDRs) of osteoporosis sufferers, especially focusing on Asian women.AIM: This study explored osteoporosis knowledge, beliefs and behaviours of women with a family history of osteoporosis, and dr... | ['Caregivers', 'Female', 'Health Behavior', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Middle Aged', 'Osteoporosis', 'Surveys and Questionnaires', 'Taiwan'] | 17,394,538 | [['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F01.145.488'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.116.198.579', 'C18.452.104.579'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.252.474.872', 'Z01.639.850']] | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Active transportation and acculturation among Latino children in San Diego County. | OBJECTIVES: To examine multiple measures of acculturation and their association with walking to school in a large population-based sample in San Diego, California.METHODS: The sample consisted of predominantly Latino children and their parents (n=812) who participated in a study to maintain healthy weights from kinderg... | ['Acculturation', 'Adolescent', 'Adult', 'California', 'Child', 'Cross-Sectional Studies', 'Female', 'Hispanic Americans', 'Humans', 'Male', 'Obesity', 'Overweight', 'Schools', 'Surveys and Questionnaires', 'Transportation', 'Walking', 'Young Adult'] | 18,353,433 | [['I01.076.201.450.050', 'I01.880.853.100.079'], ['M01.060.057'], ['M01.060.116'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.5... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Enhancement of cytotoxic activity by synthesis of peptide multimeric forms. | Synthesis of four multimeric H-Lys-His-His-Arg-Lys-Lys-His-Arg-Lys-Arg-Lys-His-His-Lys-Arg-Lys-oH peptides containing two, four, eight and sixteen branches was carried out by solid phase utilizing a lysine core matrix. These multimeric peptides enhanced activity by inhibiting the colony-forming ability of HeLa cells, f... | ['Amino Acid Sequence', 'Cell Division', 'Growth Inhibitors', 'HeLa Cells', 'Humans', 'Lysine', 'Molecular Sequence Data', 'Oligopeptides', 'Structure-Activity Relationship'] | 9,413,211 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D27.505.696.377.450'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['L01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of swirling flow on the uptakes of native and oxidized LDLs in a straight segment of the rabbit thoracic aorta. | To elucidate the physiological significance of the spiral flow in the arterial system from the viewpoint of atherogenic lipid transport, an ex vivo experimental comparative study was designed to investigate the effect of swirling flow on the distribution of native 3,3'-dioctadecylindocarbocyanine-low-density lipoprotei... | ['Animals', 'Aorta, Thoracic', 'Hemodynamics', 'Humans', 'Lipoproteins, LDL', 'Male', 'Rabbits', 'Receptors, LDL', 'Regional Blood Flow', 'Rheology'] | 20,407,083 | [['B01.050'], ['A07.015.114.056.372'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.515', 'D12.776.521.550'], ['B01.050.150.900.649.313.968.700'], ['D12.776.543.750.710.450'], ['G09.330.100.780'], ['E05.830', 'H01.671.808']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2. | The effect of spironolactone (SL) administration on 17alpha-ethynylestradiol (EE)-induced cholestasis was studied, with emphasis on expression and activity of Mrps. Adult male Wistar rats were divided into the following groups: EE (5 mg/kg daily for 5 days, s.c.), SL (200 micromol/kg daily for 3 days, i.p.), EE+SL (sam... | ['ATP Binding Cassette Transporter, Subfamily B, Member 11', 'ATP-Binding Cassette Transporters', 'Acetaminophen', 'Animals', 'Anion Transport Proteins', 'Antiporters', 'Bile', 'Blotting, Western', 'Cholestasis, Intrahepatic', 'Ethinyl Estradiol', 'Gene Expression', 'Glucuronosyltransferase', 'Glutathione', 'Liver', 'M... | 17,686,906 | [['D12.776.157.530.100.075.125', 'D12.776.157.530.450.074.500.500.250.438', 'D12.776.395.550.020.400.534', 'D12.776.543.550.192.400.534', 'D12.776.543.585.100.200.438', 'D12.776.543.585.450.074.500.500.250.438'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D02.065.199... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Promoting Children Growth and Development: A community-based cluster randomized controlled trial in rural areas of Indonesia. | OBJECTIVE: This study examined the influence of the Promote Children's Growth and Development (PCGD) intervention on children's growth and development in rural areas in Indonesia.DESIGN AND SAMPLE: A community-based nonblinded cluster randomized controlled trial was conducted. Twelve clusters of villages were matched b... | ['Body Mass Index', 'Body Weight', 'Caregivers', 'Child', 'Child Development', 'Child, Preschool', 'Education, Nonprofessional', 'Female', 'Humans', 'Indonesia', 'Infant', 'Infant, Newborn', 'Male', 'Mothers', 'Parenting', 'Rural Population', 'Surveys and Questionnaires'] | 31,099,133 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.06... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Breeding on eight strains of Pseudostellaria heterophylla based on phenotypic traits and quality in Guizhou province]. | OBJECTIVE: To provide new germplasm materials for breeding new varieties of Pseudostellaria heterophylla.METHOD: The method of single plant selection was adopted, with the comparative experiments being carried out under the same conditions in Shibing county. The 8 plants of Shibing SB-4 were compared respectively with ... | ['Breeding', 'Caryophyllaceae', 'China', 'Phenotype', 'Polysaccharides'] | 25,775,793 | [['E05.820.150', 'G05.090'], ['B01.650.940.800.575.912.250.198.500.250'], ['Z01.252.474.164'], ['G05.695'], ['D09.698']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Engineering of the H2O2-binding pocket region of a recombinant manganese peroxidase to be resistant to H2O2. | The manganese peroxidase produced by Phanerochaete chrysosporium, which catalyzes the oxidation of Mn(2+) to Mn(3+), is easily inactivated by the hydrogen peroxide (H2O2) presented in the reaction. We attempted to increase H2O2 resistance by the conformational stabilization around the H2O2-binding pocket. Based on its ... | ['Binding Sites', 'Dose-Response Relationship, Drug', 'Escherichia coli', 'Hydrogen Peroxide', 'Methionine', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Mutation', 'Oxygen', 'Peroxidases', 'Phanerochaete', 'Protein Binding', 'Protein Conformation', 'Protein Folding', 'Recombinant Proteins'] | 11,734,216 | [['G02.111.570.120'], ['G07.690.773.875', 'G07.690.936.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['E05.599.595'], ['E05.393... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Implementing informative priors for heterogeneity in meta-analysis using meta-regression and pseudo data. | Many meta-analyses combine results from only a small number of studies, a situation in which the between-study variance is imprecisely estimated when standard methods are applied. Bayesian meta-analysis allows incorporation of external evidence on heterogeneity, providing the potential for more robust inference on the ... | ['Bayes Theorem', 'Likelihood Functions', 'Markov Chains', 'Meta-Analysis as Topic', 'Monte Carlo Method', 'Network Meta-Analysis'] | 27,577,523 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.400'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Effect of thymalin on protein synthesis in the brain and conditioned-reflex activity of the progeny of neurosensitized female rats]. | Thymalin administration to two-week-old offspring of neurosensitized female rats prevented the development of protein synthesis disturbances in the central nervous system and the retention of conditioned reflex of passive avoidance. Thymalin injection to the offspring of intact female rats improved conditioned reflex r... | ['Adjuvants, Immunologic', 'Animals', 'Brain', 'Conditioning, Classical', 'Female', 'Fetal Proteins', 'Immune System Diseases', 'Nerve Tissue Proteins', 'Pregnancy', 'Rats', 'Thymus Hormones'] | 3,676,482 | [['D27.505.696.477.067'], ['B01.050'], ['A08.186.211'], ['F02.463.425.179.308'], ['D12.776.320'], ['C20'], ['D12.776.631'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['D06.472.910']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Compressive mechanical properties of the intraluminal thrombus in abdominal aortic aneurysms and fibrin-based thrombus mimics. | An intraluminal thrombus (ILT) forms in the majority of abdominal aortic aneurysms (AAAs). While the ILT has traditionally been perceived as a byproduct of aneurysmal disease, the mechanical environment within the ILT may contribute to the degeneration of the aortic wall by affecting biological events of cells embedded... | ['Aged', 'Aged, 80 and over', 'Aortic Aneurysm, Abdominal', 'Aortic Rupture', 'Endothelium, Vascular', 'Extracellular Space', 'Female', 'Fibrin', 'Humans', 'Male', 'Microscopy, Electron, Scanning', 'Middle Aged', 'Molecular Mimicry', 'Stress, Mechanical', 'Thrombosis'] | 19,058,807 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.055.185.125', 'C14.907.055.239.175', 'C14.907.109.139.175', 'C26.761.125'], ['A07.015.700.500', 'A10.272.491.355'], ['A10.082.500', 'A11.284.295'], ['D12.776.124.270'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Temperature dependence of protein-hydration hydrodynamics by molecular dynamics simulations. | The dynamics of water molecules near the protein surface are different from those of bulk water and influence the structure and dynamics of the protein itself. To elucidate the temperature dependence hydration dynamics of water molecules, we present results from the molecular dynamic simulation of the water molecules s... | ['Ovomucin', 'Plant Proteins', 'Protease Inhibitors', 'Protein Conformation', 'Temperature', 'Viscosity', 'Water'] | 17,720,293 | [['D12.776.256.159.157.675', 'D12.776.290.675', 'D12.776.395.560.760'], ['D12.776.765'], ['D27.505.519.389.745'], ['G02.111.570.820.709'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G02.930'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Synthesis and application of clindamycin succinate as a novel chiral selector for capillary electrophoresis. | A novel chiral selector, clindamycin succinate, was synthesized and first used as a chiral selector in capillary electrophoresis (CE). The chiral resolution ability of this kind of clindamycin derivation was studied by CE using some racemic drugs as model analytes. From the experimental results, it was found that both ... | ['Clindamycin', 'Electrophoresis, Capillary', 'Hydrogen-Ion Concentration', 'Molecular Structure', 'Stereoisomerism', 'Temperature'] | 21,898,800 | [['D03.383.773.532.500.125', 'D09.408.471.500.125'], ['E05.196.401.190', 'E05.301.300.190'], ['G02.300'], ['G02.111.570', 'G02.466'], ['G02.607.445.682'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Turnip Mosaic Virus Counteracts Selective Autophagy of the Viral Silencing Suppressor HCpro. | Autophagy is a conserved intracellular degradation pathway and has emerged as a key mechanism of antiviral immunity in metazoans, including the selective elimination of viral components. In turn, some animal viruses are able to escape and modulate autophagy for enhanced pathogenicity. Whether host autophagic responses ... | ['Arabidopsis', 'Arabidopsis Proteins', 'Autophagy', 'Models, Biological', 'Plant Diseases', 'Potyvirus', 'Proteolysis', 'RNA Interference', 'Ubiquitin', 'Viral Proteins'] | 29,133,371 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G04.011'], ['E05.599.395'], ['G15.610'], ['B04.715.464.600', 'B04.715.635.600', 'B04.820.578.782.600'], ['G02.111.720', 'G03.812'], ['G05.308.203.374.790'], ['D12.776.947.500'], ['D12.776.964']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The organisation of primary care in Europe: part 1 trends--position paper of the European Forum for Primary Care. | AIM: To describe and classify contemporary organisational developments in primary care across Europe.METHOD: Ten case studies have been undertaken at local sites which are exemplars of organisational practice nominated by national leaders and international experts. The selection is informed by a comprehensive literatur... | ['Europe', 'Health Policy', 'Humans', 'Interprofessional Relations', 'Managed Care Programs', 'Models, Organizational', 'National Health Programs', 'Organizational Case Studies', 'Primary Health Care', 'Professional Practice'] | 19,416,606 | [['Z01.542'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['E05.599.670', 'N04.452.534'], ['N03.349.550'], ['N03.349.380.710', 'N05.715.360.455'], ['N04.590.233.727'], ['N... | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Efficacy and safety of tolterodine in people with neurogenic detrusor overactivity. | OBJECTIVE: To compare tolterodine with oxybutynin and placebo in people with neurogenic detrusor overactivity.DESIGN: Prospective, randomized, double-blind, crossover trial plus open-label comparative stage.PARTICIPANTS: Ten participants with neurogenic detrusor overactivity due to spinal cord injury or multiple sclero... | ['Adult', 'Benzhydryl Compounds', 'Cresols', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Mandelic Acids', 'Middle Aged', 'Multiple Sclerosis', 'Muscarinic Antagonists', 'Phenylpropanolamine', 'Prospective Studies', 'Spinal Cord Injuries', 'Tolterodine Tartrate', 'Urinary Bladder, Neurogeni... | 15,478,523 | [['M01.060.116'], ['D02.455.426.559.389.115'], ['D02.455.426.559.389.657.239'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.475', 'D02.241.511.536']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Facilitating and limiting factors of workplace health promotion at Rhodes University, South Africa. | BACKGROUND: Workplace health promotion programs, when well designed and implemented are beneficial to both employees and their employers.OBJECTIVE: To investigate the factors that affect workplace health promotion initiatives intended for support staff at Rhodes University. To explore ways in which future initiatives t... | ['Adult', 'Female', 'Focus Groups', 'Health Promotion', 'Humans', 'Male', 'Qualitative Research', 'South Africa', 'Universities', 'Workforce', 'Workplace'] | 29,733,050 | [['M01.060.116'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.241.850'], ['Z01.058.290.175.735'], ['I02.783.830', 'J03.832.830'], ['N04.452.525'], ['N01.824.245.925', 'N04.452.677.975']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice. | The c-H-ras-1 gene of an B6C3F1 mouse was isolated and nucleotide sequence determined. Our study has revealed that this c-H-ras-1 gene consists of four exons, separated by three introns ranging in size from 150 to 649 bp. The coding parts of the sequence of mouse c-H-ras-1 gene show no important differences as compared... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'DNA', 'Genes, ras', 'Humans', 'Male', 'Mice', 'Mice, Inbred Strains', 'Molecular Sequence Data', 'Sequence Homology, Amino Acid'] | 8,922,043 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['G05.360.340.024.340.375.500.791.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.31... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Frontalis-Orbicularis Muscle Advancement for Correction of Upper Eyelid Ptosis: A Systematic Literature Review. | PURPOSE: To review the level of standardization of frontalis-orbicularis muscle advancement to correct severe blepharoptosis and the degree of scientific evidence supporting the procedure as a useful modality of blepharoptosis repair.METHODS: The authors searched the Medline, Lilacs, and Scopus databases for all articl... | ['Blepharoplasty', 'Blepharoptosis', 'Eyelids', 'Facial Muscles', 'Humans', 'Oculomotor Muscles', 'Surgical Flaps'] | 29,958,196 | [['E04.540.104', 'E04.680.275.090'], ['C11.338.204'], ['A01.456.505.420.504', 'A09.371.337'], ['A02.633.567.400', 'A14.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.700'], ['A10.850.710', 'E07.862.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chitin is only a minor component of the peritrophic matrix from larvae of Lucilia cuprina. | The gut of most insects is lined with a peritrophic matrix that facilitates the digestive process and protects insects from invasion by micro-organisms and parasites. It is widely accepted that the matrix is composed of chitin, proteins and proteoglycans. Here we critically re-examine the chitin content of the typical ... | ['Animals', 'Benzenesulfonates', 'Chitin', 'Chitin Synthase', 'Chitinases', 'Chitosan', 'Digestive System', 'Diptera', 'Larva', 'Pyrimidine Nucleosides', 'Wheat Germ Agglutinins'] | 11,044,665 | [['B01.050'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['D05.750.078.139', 'D09.698.211'], ['D08.811.913.400.450.460.200'], ['D08.811.277.450.207'], ['D05.750.078.139.500', 'D09.698.211.500'], ['A03'], ['B01.050.500.131.617.720.500.500.750'], ['B05.500.500', 'G07.345.500.550.500.500'], ['D03.383.742.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Parathyroid hormone attenuates radiation-induced increases in collagen crosslink ratio at periosteal surfaces of mouse tibia. | As part of our ongoing efforts to understand underlying mechanisms contributing to radiation-associated bone fragility and to identify possible treatments, we evaluated the longitudinal effects of parathyroid hormone (PTH) treatment on bone quality in a murine model of limited field irradiation. We hypothesized PTH wou... | ['Animals', 'Bone Matrix', 'Calcification, Physiologic', 'Collagen', 'Cross-Linking Reagents', 'Female', 'Mice, Inbred BALB C', 'Parathyroid Hormone', 'Periosteum', 'Spectrum Analysis, Raman', 'Tibia', 'X-Rays'] | 26,960,578 | [['B01.050'], ['A10.165.265.166'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D27.720.470.410.210'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['D06.472.699.590', 'D12.644.548.587'], ['A10... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Helical volumetric modulated arc therapy for treatment of craniospinal axis. | PURPOSE: Volumetric modulated arc therapy (VMAT) can be used with multiple isocenters to provide an effective treatment of the craniospinal axis. Additional efficiency can be achieved by simultaneously applying linear couch motion to generate a helical arc trajectory. This study investigated the treatment planning and ... | ['Algorithms', 'Cranial Irradiation', 'Humans', 'Patient Positioning', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Image-Guided', 'Radiotherapy, Intensity-Modulated', 'Retrospective Studies', 'Rotation', 'Spinal Cord', 'Spine', 'Supine Position', 'Time Factors'] | 22,115,791 | [['G17.035', 'L01.224.050'], ['E02.815.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.670', 'N02.421.585.700'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E02.815.768'], ['E02.815.635.700.700', 'L01.313.500.750.100.710.600.550.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Findings on a relationship between type A behavior and headaches. | Based on answers to a headache questionnaire college women were classified on a two-dimensional array according to their relative frequencies of both vascular (migraine) and tension (muscle contraction) pain. The various groups were then compared on a measure of the coronary-prone Type A behavior pattern. In two indepe... | ['Coronary Disease', 'Headache', 'Humans', 'Migraine Disorders', 'Psychological Tests', 'Type A Personality'] | 6,481,797 | [['C14.280.647.250', 'C14.907.585.250'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.546.399.750'], ['F04.711'], ['F01.752.747.880']] | ['Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The association between progression of coronary artery calcium and colorectal adenoma: A retrospective follow-up study of asymptomatic Koreans. | The potential relationship between coronary artery calcium (CAC) and colorectal adenoma has been widely indicated. This study aimed to investigate the relationship between the risk of colorectal adenoma and CAC progression in asymptomatic Korean adults who underwent serial assessments by colonoscopy and CAC scan.A tota... | ['Adenoma', 'Asymptomatic Diseases', 'Calcium', 'Colonoscopy', 'Colorectal Neoplasms', 'Coronary Angiography', 'Coronary Artery Disease', 'Coronary Vessels', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Multidetector Computed Tomography', 'ROC Curve', 'Republic of... | 31,626,147 | [['C04.557.470.035'], ['C23.550.291.187'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.49... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Arbuscular mycorrhizal fungus modulates the phytotoxicity of Cd via combined responses of enzymes, thiolic compounds, and essential elements in the roots of Phragmites australis. | The positive effects of arbuscular mycorrhizal (AM) fungi on host plants under heavy metal (HM) stress conditions have been widely recognized. HMs are known to induce phytotoxicity through 1) the production of reactive oxygen species (ROS), 2) the direct interaction with thiol groups or 3) the competition with essentia... | ['Cadmium', 'Catalase', 'Copper', 'Metals, Heavy', 'Mycorrhizae', 'Plant Roots', 'Poaceae', 'Stress, Physiological', 'Sulfhydryl Compounds', 'Superoxide Dismutase', 'Symbiosis'] | 28,850,908 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D08.811.682.732.332'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D01.268.556', 'D01.552.544'], ['A18.400.525', 'A19.690', 'B01.300.655', 'B05.550'], ['A18.400'], ['B01.650.940.800.575.912.250.822'], ['G07.775'], ['D02.886.489'], ['D08.811.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sequences encoding the protein and RNA components of ribonuclease P from Streptomyces bikiniensis var. zorbonensis. | The genes encoding the RNA (rnpB) and protein (rnpA) subunits of ribonuclease P (RNase P) of Streptomyces bikiniensis var. zorbonensis have been cloned by complementing the temperature-sensitive growth phenotype of Escherichia coli strains that carry mutations in these genes. The rnpB sequence of S. bikiniensis include... | ['Amino Acid Sequence', 'Base Sequence', 'DNA, Bacterial', 'Endoribonucleases', 'Escherichia coli Proteins', 'Genetic Variation', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'RNA, Bacterial', 'RNA, Catalytic', 'Ribonuclease P', 'Sequence Alignment', 'Streptomyces'] | 1,379,566 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['D08.811.277.352.355.350', 'D08.811.277.352.700.350'], ['D12.776.097.275'], ['G05.365'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.735.473'], ['D08.811.797', 'D13.44... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A new method of analysis of peroxydisulfate using ion chromatography and its application to the simultaneous determination of peroxydisulfate and other common inorganic ions in a peroxydisulfate matrix. | A new method for the determination of peroxydisulfate using ion chromatography has been developed. Elution of peroxydisulfate was effected by isocratic elution using 200 mM NaOH at 40°C. A modification of the method using gradient elution was able to simultaneously determine other common inorganic ions (nitrate, nitrit... | ['Anions', 'Chromatography, Ion Exchange', 'Linear Models', 'Peroxides', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Sodium Hydroxide', 'Sulfates', 'Temperature'] | 21,185,030 | [['D01.248.497.158'], ['E05.196.181.400.383'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['D01.248.497.158.685.750', 'D01.339.431.374', 'D01.650.550.750', 'D02.389.338'], ['E05.318.370.72... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The prevalence and risk factors analysis of serum antibody to hepatitis C virus in the elders in northeast Taiwan. | BACKGROUND: Hepatitis C virus (HCV) infection will result in liver cirrhosis and hepatocellular carcinoma, which are the leading causes of death in Taiwan. The prevalence of antibody to HCV (anti-HCV) was 2%-3% in Taipei city. However, it can be as high as 20% to 60% in Central and Southern part of Taiwan. In I-Lan, a ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'Male', 'Middle Aged', 'Needles', 'Risk Factors', 'Seroepidemiologic Studies', 'Transfusion Reaction'] | 12,716,008 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['D12.776.124.486.485.114.254.450.510', 'D12.776.124.790.651.114.254.450.510', 'D12.776.377.715.548.114.254.450.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical audit of multidisciplinary care at a medium-sized hospital in Spain. | BACKGROUND: Multidisciplinary care is a key enabler in the provision of high quality care for cancer patients. Despite compelling evidence supporting their benefit to patients and for providers, multidisciplinary cancer conferences (MCC) are not universally occurring. Team composition of MCC reflects the multidisciplin... | ['Clinical Audit', 'Decision Making', 'Humans', 'Patient Care Team', "Practice Patterns, Physicians'", 'Prognosis', 'Prospective Studies', 'Quality of Health Care'] | 24,597,686 | [['N04.761.700.250', 'N05.700.175'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.715'], ['N04.590.374.577', 'N05.300.625'], ['E01.789'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['N04.761', 'N05.715']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Endothelium-dependent relaxation of canine pulmonary artery after prolonged lung graft preservation in University of Wisconsin solution: role of L-arginine supplementation. | BACKGROUND: The University of Wisconsin (UW) solution has been demonstrated to enhance pulmonary allograft preservation. Endothelial nitric oxide (NO) production has been shown to be significantly impaired after ischemia and reperfusion (I/R) injury. The present experiments aimed to determine the protective effects of ... | ['Acetylcholine', 'Adenosine', 'Adenosine Diphosphate', 'Allopurinol', 'Animals', 'Arginine', 'Dogs', 'Endothelium, Vascular', 'Female', 'Glutathione', 'Insulin', 'Lung', 'Lung Transplantation', 'Male', 'Molsidomine', 'Organ Preservation Solutions', 'Pulmonary Artery', 'Raffinose', 'Sodium Fluoride', 'Tissue Preservati... | 15,135,376 | [['D02.092.211.111'], ['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.160'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.015.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
PLANET TOPERS: Planets, Tracing the Transfer, Origin, Preservation, and Evolution of their ReservoirS. | The Interuniversity Attraction Pole (IAP) 'PLANET TOPERS' (Planets: Tracing the Transfer, Origin, Preservation, and Evolution of their Reservoirs) addresses the fundamental understanding of the thermal and compositional evolution of the different reservoirs of planetary bodies (core, mantle, crust, atmosphere, hydrosph... | ['Evolution, Planetary', 'Exobiology', 'Extraterrestrial Environment', 'Planets'] | 27,337,974 | [['G01.060.275', 'G01.311.290'], ['H01.158.273.295'], ['G01.060.075.159', 'G16.500.275.240'], ['G01.060.075.680', 'G01.060.075.730.700']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Decreased T3 and T4 levels following topical application of povidone-iodine in premature neonates. | Thyroid function and iodine levels of 30 preterm neonates were examined before and up to five days after topical exposure to 10% povidone-iodine application. Urinary iodine excretion significantly increased in the group closest to term (8.9 +/- 1.2 mg I/g creatinine x 10) vs controls (3.5 +/- 0.5 mg; p < 0.01). T3 leve... | ['Administration, Topical', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Iodine', 'Povidone-Iodine', 'Thyroxine', 'Triiodothyronine'] | 7,820,214 | [['E02.319.267.120'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['D01.268.380.400'], ['D01.475.557.500', 'D02.455.326.271.884.533.710', 'D03.383.773.812.615.630', 'D05.750.716.721.838.745', 'D25.720.716.721.838.745', 'J01.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study. | BACKGROUND: Recent studies indicate a potential role of Saccharomyces boulardii in the prevention of Helicobacter pylori treatment-related side-effects and also in improvement of eradication rate. Our aim is to investigate the efficacy and safety of S. boulardii in the prevention of side-effects related to H. pylori er... | ['2-Pyridinylmethylsulfinylbenzimidazoles', 'Adult', 'Aged', 'Amoxicillin', 'Clarithromycin', 'Diarrhea', 'Double-Blind Method', 'Drug Therapy, Combination', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Lansoprazole', 'Male', 'Middle Aged', 'Nausea', 'Probiotics', 'Prospective Studies', 'Sacch... | 17,669,103 | [['D02.886.640.074', 'D03.383.725.024', 'D03.633.100.103.034'], ['M01.060.116'], ['M01.060.116.100'], ['D02.065.589.099.750.750.050.050', 'D02.886.108.750.750.050.050', 'D03.633.100.300.750.750.050.050'], ['D02.540.576.500.992.100'], ['C23.888.821.214'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N0... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Resolution of model Holliday junctions by yeast endonuclease: effect of DNA structure and sequence. | The resolution of Holliday junctions in DNA involves specific cleavage at or close to the site of the junction. A nuclease from Saccharomyces cerevisiae cleaves model Holliday junctions in vitro by the introduction of nicks in regions of duplex DNA adjacent to the crossover point. In previous studies [Parsons and West ... | ['Base Sequence', 'DNA, Fungal', 'Endodeoxyribonucleases', 'Fungal Proteins', 'Methylation', 'Models, Genetic', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Recombination, Genetic', 'Saccharomyces cerevisiae', 'Sequence Homology, Nucleic Acid', 'Substrate Specificity'] | 2,653,810 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.300'], ['D08.811.277.352.335.350', 'D08.811.277.352.355.325'], ['D12.776.354'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['E05.599.395.397'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['G05.728'], ['B01.300.107.79... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Demographic characteristics of doctors who intend to follow clinical academic careers: UK national questionnaire surveys. | OBJECTIVES: It is well recognised that women are underrepresented in clinical academic posts. Our aim was to determine which of a number of characteristics-notably gender, but also ethnicity, possession of an intercalated degree, medical school attended, choice of specialty-were predictive of doctors' intentions to fol... | ['Asian Continental Ancestry Group', 'Career Choice', 'Cohort Studies', 'Demography', 'Female', 'Humans', 'Male', 'Physicians', 'Sex Factors', 'Surveys and Questionnaires', 'Teaching', 'Workforce'] | 25,136,138 | [['M01.686.508.200'], ['F02.463.785.373.346.400'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.810', 'N02.360.810'], ['N05.715.350.675', 'N06.850.490.875'], ['E05.318.308.980', 'N... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Interacting effects of multiple roles on women's health. | Our study tests several hypotheses concerning the effects of employment, marriage, and motherhood on women's general physical health. These hypotheses predict how the health effect of each role varies, depending on specific role characteristics and the other roles a woman holds. Our analyses utilize longitudinal panel ... | ['Adolescent', 'Adult', 'Employment', 'Female', 'Health Status', 'Humans', 'Longitudinal Studies', 'Marriage', 'Maternal Age', 'Mother-Child Relations', 'Pregnancy', "Women's Health", 'Workload'] | 9,785,695 | [['M01.060.057'], ['M01.060.116'], ['N01.824.245'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.5... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[From the regional hospital to the Clinical Center in Sarajevo--100 years of work and development]. | In the course of the past 100 years of the Regional Hospital, the Clinical Centre now experienced a number of organizational, functional and technological changes. There 6 striking periods: 1. Period of the Regional Hospital in Sarajevo, 1894-1918; 2. General State Hospital, 1919-1940; 3. World War 2, 1941-1945; 4. Cli... | ['Bosnia and Herzegovina', 'History, 19th Century', 'History, 20th Century', 'Hospitals'] | 7,752,701 | [['Z01.542.248.160'], ['K01.400.504.937'], ['K01.400.504.968'], ['N02.278.421']] | ['Geographicals [Z]', 'Humanities [K]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A contactin-receptor-like protein tyrosine phosphatase beta complex mediates adhesive communication between astroglial cells and gonadotrophin-releasing hormone neurones. | Although it is well established that gonadotrophin-releasing hormone (GnRH) neurones and astrocytes maintain an intimate contact throughout development and adult life, the cell-surface molecules that may contribute to this adhesiveness remain largely unknown. In the peripheral nervous system, the glycosylphosphatidyl i... | ['Animals', 'Astrocytes', 'Cell Adhesion', 'Cell Adhesion Molecules, Neuronal', 'Cell Communication', 'Cells, Cultured', 'Contactins', 'Female', 'Gonadotropin-Releasing Hormone', 'Hypothalamus', 'Mice', 'Neurons', 'Receptor-Like Protein Tyrosine Phosphatases, Class 5', 'Recombinant Fusion Proteins'] | 17,927,663 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['G04.022'], ['D12.776.395.550.200.250', 'D12.776.543.550.200.250', 'D23.050.301.350.250'], ['G04.085'], ['A11.251'], ['D12.776.395.550.200.250.325', 'D12.776.395.550.448.250', 'D12.776.543.484.500.250', 'D12.776.543.550.200.250.325', 'D12.776.543.550.418.250', 'D23.050.301... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feather mites are potentially an important source of allergens for pigeon and budgerigar keepers. | BACKGROUND: Previous studies on allergy to feathers have not addressed whether organisms living on feathers (mites, lice, moulds) are a source of allergens.OBJECTIVE: To investigate whether feather mites produced allergens of clinical relevance to bird keepers.METHODS: We examined serum IgE responses of 96 pigeon breed... | ['Allergens', 'Animals', 'Antigens, Dermatophagoides', "Bird Fancier's Lung", 'Blotting, Western', 'Columbidae', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Feathers', 'Glycoproteins', 'Immunoglobulin E', 'Microscopy, Electron, Scanning', 'Mites', 'Parrots', 'Radioallergosorbent Test'] | 9,117,882 | [['D23.050.063'], ['B01.050'], ['D23.050.181'], ['C08.381.483.125.125', 'C08.674.055.125', 'C20.543.480.680.075.125', 'C24.125'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B01.050.150.900.248.165.150'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.35... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pain in knee arthrography: comparison of air vs. CO2 and reaspiration vs. no reaspiration. | A prospective study of 255 patients undergoing double-contrast arthrography of the knee was performed to evaluate postexamination knee pain after two procedural modifications: (1) intraarticular carbon dioxide versus room air and (2) postprocedural joint reaspiration versus no reaspiration. A moderate or severe increas... | ['Adult', 'Air', 'Carbon Dioxide', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Knee Joint', 'Male', 'Middle Aged', 'Pain', 'Prospective Studies', 'Radiography'] | 6,781,262 | [['M01.060.116'], ['G16.500.275.063.150', 'N06.230.300.100.150'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['M01.060.116.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E05.318.372.500.750... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Diagnostic and prognostic value of stress echo-pacing in patients with implanted AAI pace-maker]. | UNLABELLED: The aim of this study was to assess the utility, safety and prognostic value of echocardiographic stress test (EST) in non-invasive diagnosis of ischemic heart disease in patients (pts) with implanted pacemaker, with and without left ventricle hypertrophy.MATERIAL AND METHODS: EST was performed in 40 patien... | ['Aged', 'Coronary Angiography', 'Echocardiography, Stress', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Pacemaker, Artificial', 'Predictive Value of Tests', 'Prognosis', 'Sensitivity and Specificity', 'Time Factors'] | 16,194,018 | [['M01.060.116.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E01.370.350.130.750.228', 'E01.370.350.850.220.228', 'E01.370.370.380.220.228'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neurovascular coupling in terms of a control system: validation of a second-order linear system model. | Neurovascular coupling (NC) adapts cerebral blood flow to cortical activity. Functional transcranial Doppler (f-TCD) investigations revealed a typical time course of evoked blood flow responses with an initial overshoot and a stabilization at a lower, but stable, level. This blood flow reaction can be described in term... | ['Adult', 'Algorithms', 'Blood Flow Velocity', 'Cerebrovascular Circulation', 'Humans', 'Linear Models', 'Photic Stimulation', 'Reference Values', 'Reproducibility of Results', 'Ultrasonography, Doppler, Transcranial', 'Visual Cortex'] | 11,397,527 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity. | For a given body mass index (BMI), mortality is higher in patients with central compared to generalized obesity. Glucocorticoids play an important role in determining body fat distribution, but circulating cortisol concentrations are reported to be normal in obese patients. Our recent studies show enhanced conversion o... | ['Adipose Tissue', 'Adult', 'Body Constitution', 'Body Mass Index', 'Cortisone', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Obesity', 'Tetrahydrocortisol', 'Tetrahydrocortisone'] | 10,084,590 | [['A10.165.114'], ['M01.060.116'], ['E01.370.600.115', 'G07.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D04.210.500.745.745.183', 'D06.472.040.585.478.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.4... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Contrasting effects of low or high copper intake on rat tissue lipid essential fatty acid composition. | The effects of low copper intake or copper supplementation on the metabolism of stearic acid have been studied previously, but their effects on essential fatty acids have not been reported. Male Sprague-Dawley rats were fed for 12 weeks on pelleted semi-synthetic diets containing less than 1 mg/kg copper (low copper), ... | ['Adipose Tissue', 'Animal Feed', 'Animals', 'Copper', 'Dose-Response Relationship, Drug', 'Fatty Acids', 'Fatty Acids, Essential', 'Food, Fortified', 'Lipids', 'Liver', 'Male', 'Myocardium', 'Rats', 'Rats, Inbred Strains'] | 3,994,296 | [['A10.165.114'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G07.690.773.875', 'G07.690.936.500'], ['D10.251'], ['D10.251.355.310'], ['G07.203.300.515', 'J02.500.515'], ['D10'], ['A03.620'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate. | BACKGROUND: The activity of Bruton's tyrosine kinase (Btk) is important for the maturation of B cells. A variety of point mutations in this enzyme result in a severe human immunodeficiency known as X-linked agammaglobulinemia (XLA). Btk contains a pleckstrin-homology (PH) domain that specifically binds phosphatidylinos... | ['Agammaglobulinaemia Tyrosine Kinase', 'Agammaglobulinemia', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Calorimetry', 'Crystallography, X-Ray', 'Dimerization', 'Humans', 'Inositol Phosphates', 'Membrane Lipids', 'Models, Molecular', 'Molecular Sequence Data', 'Phosphatidylinositols', 'Point Mutation', 'Protein... | 10,196,129 | [['D08.811.913.696.620.682.725.025'], ['C15.378.147.142', 'C15.604.515.032', 'C20.673.088'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['E05.196.131'], ['E05.196.309.742.225'], ['G02.206', 'G03.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.800.519.400', 'D09... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Model-based estimates of transmission of respiratory syncytial virus within households. | INTRODUCTION: Respiratory syncytial virus (RSV) causes a significant respiratory disease burden in the under 5 population. The transmission pathway to young children is not fully quantified in low-income settings, and this information is required to design interventions.METHODS: We used an individual level transmission... | ['Adolescent', 'Child', 'Child, Preschool', 'Cohort Studies', 'Epidemics', 'Family Characteristics', 'Female', 'Humans', 'Infant', 'Kenya', 'Male', 'Models, Theoretical', 'Poverty', 'Respiratory Syncytial Virus Infections', 'Respiratory Syncytial Virus, Human', 'Rural Population', 'Seasons', 'Viral Load'] | 30,591,267 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N06.850.290.200'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Prevalence and significance of cardiovascular disease and hypertension in elderly patients with dementia and depression. | The prevalence and significance of clinical heart disease and hypertension were compared in three groups of elderly patients. One group was diagnosed as dementia of an Alzheimer's type (AD), another as multiinfarct dementia (MID), and the third as major depression. Clinical heart disease and hypertension were uncommon ... | ['Aged', 'Alzheimer Disease', 'Cardiovascular Diseases', 'Dementia', 'Depressive Disorder', 'Female', 'Heart Diseases', 'Humans', 'Hypertension', 'Male', 'Maryland'] | 4,019,997 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['C14'], ['C10.228.140.380', 'F03.615.400'], ['F03.600.300'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
A novel monoacyldiglycosyl-monoacylglycerol from Flavobacterium marinotypicum. | A monoacyldiglycosyl-monoacylglycerol was isolated from the Gram-negative bacterium Flavobacterium marinotypicum (ATCC 19260). The structure was determined, mainly by spectral data, to be [alpha-glucopyranosyl-(1-->3)-O-(6-O-acyl-alpha-mannopyranosyl)]-O- acylglycerol. | ['Carbohydrate Sequence', 'Flavobacterium', 'Glycolipids', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'Spectrometry, Mass, Fast Atom Bombardment'] | 10,217,728 | [['G02.111.570.160', 'L01.453.245.667.160'], ['B03.440.080.190.250', 'B03.440.400.425.310.250'], ['D09.400.410', 'D10.390'], ['E05.196.867.519'], ['L01.453.245.667'], ['E05.196.566.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Contact versus flexure fatigue of a fiber-filled composite. | OBJECTIVE: The intent of this project was to examine the effect of two different modes of fatigue loading, contact and flexure, on the flexure strength of a dental composite.METHODS: The composite was Restolux (a fiber-filled composite) formed as bars 3 mm x 3 mm x 25 mm in size. The cyclic loading ranges were 30-50, 6... | ['Air', 'Composite Resins', 'Dental Materials', 'Ethanol', 'Finite Element Analysis', 'Humans', 'Materials Testing', 'Pliability', 'Saliva, Artificial', 'Solvents', 'Stress, Mechanical', 'Surface Properties', 'Temperature', 'Time Factors', 'Water'] | 16,876,859 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['D25.339', 'D27.720.102.339', 'J01.637.051.339'], ['D02.033.375'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['G... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Backbone and side chain assignments of the second RNA-binding domain of Musashi-1 in its free form and in complex with 5-mer RNA. | Musashi1 (Msi1) is an RNA-binding protein that is involved in cell fate determination. Here, we report the 1H, 15N, and 13C resonance assignments of Msi1 second RNA-binding domain in free form and in complex with RNA. The assignments can be utilized for NMR structure and dynamics analyses of the Msi1:RNA complex, and m... | ['Animals', 'Mice', 'Nerve Tissue Proteins', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Binding', 'Protein Domains', 'RNA', 'RNA-Binding Proteins'] | 28,808,919 | [['B01.050'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.631'], ['E05.196.867.519.550'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['D13.444.735'], ['D12.776.157.725', 'D12.776.664.962']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Supersensitivity to catecholamines after impairment of extraneuronal uptake or catechol-O-methyl transferase. | In cat papillary muscle and nictitating membrane block of extraneuronal catechol-O-methyl transferase (COMT) by 3',4'-dihydroxy-alpha-methyl propiophenone (U-0521) or of extraneuronal uptake by hydrocortisone causes supersensitivity to catecholamines whenever the experimental conditions result in a high sensitivity of ... | ['Animals', 'Catechol O-Methyltransferase', 'Cats', 'Hydrocortisone', 'Kinetics', 'Monoamine Oxidase Inhibitors', 'Neurons', 'Nictitating Membrane', 'Norepinephrine', 'Normetanephrine', 'Papillary Muscles', 'Receptors, Cell Surface'] | 169,167 | [['B01.050'], ['D08.811.913.555.500.250'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['G01.374.661', 'G02.111.490'], ['D27.505.519.389.616'], ['A08.675', 'A11.671'], ['A13.660'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of subtraction methods in three-dimensional contrast-enhanced peripheral MR angiography. | PURPOSE: To compare the effectiveness of three image subtraction algorithms designed to improve arterial conspicuity in first-pass contrast-enhanced magnetic resonance (MR) angiography.MATERIALS AND METHODS: Three subtraction methods were analyzed through computer simulations, phantom studies, and clinical studies. The... | ['Algorithms', 'Angiography, Digital Subtraction', 'Computer Simulation', 'Contrast Media', 'Gadolinium DTPA', 'Humans', 'Magnetic Resonance Angiography', 'Peripheral Vascular Diseases', 'Phantoms, Imaging'] | 11,997,895 | [['G17.035', 'L01.224.050'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['L01.224.160'], ['D27.505.259.500', 'D27.720.259'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice. | OBJECTIVES: ACAT2 is the exclusive cholesterol-esterifying enzyme in hepatocytes and enterocytes. Hepatic ABCA1 transfers unesterified cholesterol (UC) to apoAI, thus generating HDL. By changing the hepatic UC pool available for ABCA1, ACAT2 may affect HDL metabolism. The aim of this study was to reveal whether hepatic... | ['ATP Binding Cassette Transporter 1', 'Animals', 'Base Sequence', 'Cell Line', 'Down-Regulation', 'Lipoproteins, HDL', 'Liver', 'Male', 'Mice', 'Mice, Knockout', 'Oligonucleotides, Antisense', 'Sterol O-Acyltransferase'] | 24,695,360 | [['D12.776.157.530.100.050.500', 'D12.776.395.550.020.381.500', 'D12.776.543.550.192.381.500', 'D12.776.543.585.100.190.500'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D10.532.432', 'D12.776.521.479'], ['A03.620'], ['B0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Etiologic types of end-stage chronic liver disease in adults: analysis of prevalence and their temporal changes from a study on native liver explants. | BACKGROUND: Whole native livers from orthotopic liver transplant (LT) recipients provide an ideal resource material for the proper identification and etiologic evaluation of end-stage liver diseases in these patients. This study determined the etiologic types of chronic liver disease (CLD) in adults of our geographic r... | ['Adolescent', 'Adult', 'Aged', 'Carcinoma, Hepatocellular', 'End Stage Liver Disease', 'Fatty Liver', 'Female', 'Hepatitis B', 'Hepatitis C', 'Humans', 'India', 'Liver', 'Liver Cirrhosis', 'Liver Neoplasms', 'Liver Transplantation', 'Male', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Prevalence'] | 22,751,227 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C06.552.308.500.177'], ['C06.552.241'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['C01.221.250.750', 'C01.925.440.440', 'C01.92... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Spiral T1 Spin-Echo for Routine Postcontrast Brain MRI Exams: A Multicenter Multireader Clinical Evaluation. | BACKGROUND AND PURPOSE: Spiral MR imaging has several advantages compared with Cartesian MR imaging that can be leveraged for added clinical value. A multicenter multireader study was designed to compare spiral with standard-of-care Cartesian postcontrast structural brain MR imaging on the basis of relative performance... | ['Adult', 'Aged', 'Artifacts', 'Brain', 'Female', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neuroimaging'] | 32,029,467 | [['M01.060.116'], ['M01.060.116.100'], ['E05.047'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.350.578', 'E01.370.376.537', 'E05.629']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Evaluation of API 20 NE in routine diagnostics of nonfermenting gram-negative rod-shaped bacteria. | 292 strains of non-fermenting Gram-negative rod-shaped bacteria were determined by standard methods and tested in a new commercial microidentification-system, the API 20 NE (api Biom?rieux). A total of 282 (= 96,6%) strains were identified conformably; 130 (= 46,1%) after 24 h and 77 (= 27,3%) within 48 h. In 75 (= 26,... | ['Alcaligenes', 'Bacteriological Techniques', 'Carbohydrate Metabolism', 'Flavobacterium', 'Gram-Negative Bacteria', 'Moraxella', 'Pseudomonas'] | 3,890,425 | [['B03.440.400.425.115.050', 'B03.660.075.090.344.050'], ['E01.370.225.875.150', 'E05.200.875.150'], ['G02.111.158', 'G03.191'], ['B03.440.080.190.250', 'B03.440.400.425.310.250'], ['B03.440'], ['B03.440.400.425.537.525', 'B03.660.250.530.525'], ['B03.440.400.425.625.625', 'B03.660.250.580.590']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of topical corticosteroid application frequency on histamine-induced wheals. | BACKGROUND: Very few studies have been conducted to assess the effect of corticosteroid application frequency to attain maximum benefit with minimum side-effects.OBJECTIVES: Compare the efficacy of twice-daily, once-daily and alternate-day applications of clobetasol propionate (0.05%) and compare whether an initial onc... | ['Administration, Cutaneous', 'Clobetasol', 'Drug Administration Schedule', 'Glucocorticoids', 'Histamine', 'Humans', 'Treatment Outcome', 'Urticaria'] | 15,869,544 | [['E02.319.267.120.060'], ['D04.210.500.908.093.250'], ['E02.319.283'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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