Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Binocular indirect argon laser photocoagulator. | The binocular indirect argon laser photocoagulator was newly designed to enable visualisation of the entire fundus during panretinal laser photocoagulation and to treat retinal tears immediately after buckling procedures of the sclera. The lamp housing of the binocular ophthalmoscope was remodelled and adjusted so that... | ['Argon', 'Humans', 'Laser Therapy', 'Lasers', 'Retina', 'Retinal Detachment', 'Retinal Diseases'] | 7,196,254 | [['D01.268.613.050', 'D01.362.641.113'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['E07.632.490', 'E07.710.520'], ['A09.371.729'], ['C11.768.648'], ['C11.768']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abalone collagens: immunological properties and seasonal changes of their mRNA levels. | The antisera were raised against pepsin-solubilized abalone collagen and its corresponding gelatin. The reactivity against abalone collagen was higher with the anti-collagen than anti-gelatin antiserum. The two antisera recognized all type I collagens from various vertebrates, whereas these had no reactivity against ve... | ['Animals', 'Cattle', 'Collagen', 'Cross Reactions', 'Female', 'Mollusca', 'RNA, Messenger', 'Rabbits', 'Rats', 'Seasons'] | 10,825,665 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G12.122.281'], ['B01.050.500.644'], ['D13.444.735.544'], ['B01.050.150.900.649.313.968.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
dbCRSR: a manually curated database for regulation of cancer radiosensitivity. | Radiotherapy is used to treat approximately 50% of all cancer patients, with varying prognoses. Intrinsic radiosensitivity is an important factor underlying the radiotherapeutic efficacy of this precise treatment. During the past decades, great efforts have been made to improve radiotherapy treatment through multiple s... | ['Animals', 'Data Curation', 'Data Mining', 'Databases, Bibliographic', 'Humans', 'Neoplasms', 'Radiation Tolerance'] | 29,860,480 | [['B01.050'], ['L01.313.500.875.500', 'L01.453.245.332'], ['L01.313.500.750.280.199', 'L01.470.625'], ['L01.313.500.750.300.188.300', 'L01.470.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['G04.712', 'G07.738']] | ['Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevalence of diabetic retinopathy in children and adolescents with type-1 diabetes attending summer camps in France. | OBJECTIVE: To evaluate, using fundus photography, the prevalence of diabetic retinopathy (DR) in young diabetic subjects attending summer camps run by the Aide aux Jeunes Diab?tiques Association (Aid to Young Diabetics).RESEARCH DESIGN AND METHODS: Five hundred and four children and adolescents (250 boys and 254 girls)... | ['Adolescent', 'Camping', 'Child', 'Child, Preschool', 'Diabetes Mellitus, Type 1', 'Diabetic Retinopathy', 'Female', 'Fluorescein Angiography', 'France', 'Glycated Hemoglobin A', 'Humans', 'Male', 'Prediabetic State', 'Prevalence'] | 17,625,942 | [['M01.060.057'], ['I03.450.642.159'], ['M01.060.406'], ['M01.060.406.448'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E01.370.370.050.350', 'E01.370.380.250'], ['Z01.542.286'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Sustainability criteria for assessing nanotechnology applicability in industrial wastewater treatment: Current status and future outlook. | Application of engineered nanomaterials for the treatment of industrial effluents and to deal with recalcitrant pollutants has been noticeably promoted in recent years. Laboratory, pilot and full-scale studies emphasize the potential of this technology to offer promising treatment options to meet the future needs for c... | ['Environmental Pollutants', 'Environmental Restoration and Remediation', 'Industry', 'Nanostructures', 'Nanotechnology', 'Waste Water', 'Water Purification'] | 30,731,376 | [['D27.888.284'], ['N06.230.080.600', 'N06.850.460.375'], ['J01.576'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['D20.944.932', 'N06.850.460.710.865'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Peptides derived from specific interaction sites of the fibroblast growth factor 2-FGF receptor complexes induce receptor activation and signaling. | Basic fibroblast growth factor (FGF2, bFGF) is the most extensively studied member of the FGF family and is involved in neurogenesis, differentiation, neuroprotection, and synaptic plasticity in the CNS. FGF2 executes its pleiotropic biologic actions by binding, dimerizing, and activating FGF receptors (FGFRs). The pre... | ['Animals', 'Apoptosis', 'Cell Differentiation', 'Cell Survival', 'Cells, Cultured', 'Cerebellum', 'Dendrimers', 'Drug Partial Agonism', 'Fibroblast Growth Factor 2', 'Ligands', 'Models, Molecular', 'Neurites', 'Neurons', 'Neuroprotective Agents', 'Oligopeptides', 'Phosphorylation', 'Rats', 'Rats, Wistar', 'Receptor, F... | 20,374,425 | [['B01.050'], ['G04.146.954.035'], ['G04.152'], ['G04.346'], ['A11.251'], ['A08.186.211.132.810.428.200'], ['D05.750.327', 'E02.319.300.380.200', 'J01.637.512.600.200'], ['G07.690.773.968.154.500'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['D27.720.470.480'], ['E05.599.595'], ['A08.675.256.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Streptomyces caldifontis sp. nov., isolated from a hot water spring of Tatta Pani, Kotli, Pakistan. | A Gram-staining positive, non-motile, rod-shaped, catalase positive and oxidase negative bacterium, designated NCCP-1331T, was isolated from a hot water spring soil collected from Tatta Pani, Kotli, Azad Jammu and Kashmir, Pakistan. The isolate grew at a temperature range of 18-40 °C (optimum 30 °C), pH 6.0-9.0 (optimu... | ['Bacterial Typing Techniques', 'Base Composition', 'DNA, Bacterial', 'DNA, Ribosomal', 'Fatty Acids', 'Hot Springs', 'Pakistan', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Streptomyces'] | 27,730,318 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['D13.444.308.212'], ['D13.444.308.475'], ['D10.251'], ['G01.311.355.750.500', 'G16.500.275.260.500'], ['Z01.252.245.723'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['B03.300.390.400.810.768', 'B03.510.024.997.775', 'B03.51... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Big endothelin in patients with complicated Plasmodium falciparum malaria. | Plasma concentrations of big endothelin-1 were determined by ELISA in 18 patients with complicated Plasmodium falciparum malaria in Bangkok. Before therapy, elevated levels were recorded (21 +/- 12 vs. 2.9 +/- 1.1 pmol/L in age- and sex-matched healthy subjects; P < .001). Even 7 days after therapy, elevated concentrat... | ['Antimalarials', 'Artemisinins', 'Artesunate', 'Endothelin-1', 'Endothelins', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Interleukin-6', 'Malaria, Cerebral', 'Malaria, Falciparum', 'Matched-Pair Analysis', 'Platelet Count', 'Protein Precursors', 'Renal Insufficiency', 'Sesquiterpenes', 'Tumor Necrosis Factor-alph... | 8,627,087 | [['D27.505.954.122.250.100.085'], ['D01.248.497.158.685.750.212', 'D01.339.431.374.212', 'D01.650.550.750.200', 'D02.389.338.055', 'D02.455.849.765.211'], ['D01.248.497.158.685.750.212.500', 'D01.339.431.374.212.500', 'D01.650.550.750.200.500', 'D02.389.338.055.500', 'D02.455.849.765.211.500'], ['D12.644.276.400.225', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Zero-stress state of intra- and extraparenchymal airways from human, pig, rabbit, and sheep lung. | Alterations in airway wall anatomic properties and the consequential effects on airway narrowing have been assessed by use of computational models. In these models, it is generally assumed that at zero transmural pressure the airway wall exists in a zero-stress state. Many studies have shown that this is often not the ... | ['Adolescent', 'Adult', 'Animals', 'Female', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Pressure', 'Rabbits', 'Sheep', 'Swine'] | 11,842,066 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ['G01.374.715'], ['B01.050.150.900.649.313.968.700'], ['B01.050.150.900.649.313.500.380.791'], ['B01.050.150.900.649.313.500.880']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic Acid, an important metabolite of proanthocyanidins in humans. | Grape seed extract provides a concentrated source of polyphenols, most of which are proanthocyanidins. Polymeric proanthocyanidins are poorly absorbed in the small intestine of humans, and exposure may result from metabolism to phenolic acids by colonic bacteria. Any biological effects of proanthocyanidins may be due t... | ['Biflavonoids', 'Catechin', 'Diet', 'Diet Records', 'Dietary Supplements', 'Female', 'Flavonoids', 'Fruit', 'Humans', 'Hydroxybenzoates', 'Male', 'Middle Aged', 'Phenols', 'Polyphenols', 'Proanthocyanidins', 'Propionates', 'Seeds', 'Tea', 'Vegetables', 'Vitis'] | 15,315,398 | [['D03.383.663.283.266.450.190', 'D03.633.100.150.266.450.190'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['G07.203.650.240'], ['N04.452.859.360'], ['G07.203.300.456', 'J02.500.456'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Parturition failure in mice lacking Mamld1. | In mice, the onset of parturition is triggered by a rapid decline in circulating progesterone. Progesterone withdrawal occurs as a result of functional luteolysis, which is characterized by an increase in the enzymatic activity of 20á-hydroxysteroid dehydrogenase (20á-HSD) in the corpus luteum and is mediated by the pr... | ['Animals', 'Cell Line', 'Cholesterol Side-Chain Cleavage Enzyme', 'Estradiol Dehydrogenases', 'Female', 'Gene Expression Regulation, Enzymologic', 'Male', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Ovary', 'Parturition', 'Pregnancy', 'STAT5 Transcription Factor', 'Transcription Factors'] | 26,435,405 | [['B01.050'], ['A11.251.210'], ['D08.244.453.484.250', 'D08.244.453.915.212', 'D08.811.682.690.708.170.425.250', 'D08.811.682.690.708.170.915.212', 'D12.776.422.220.453.484.250', 'D12.776.422.220.453.915.212'], ['D08.811.682.047.436.375.280'], ['G05.308.320'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.99... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphological and pathologic changes of experimental chronic atrophic gastritis (CAG) and the regulating mechanism of protein expression in rats. | OBJECTIVE: To study the pathologic change and molecular regulation in cell proliferation and apoptosis of gastric mucosa in rats with chronic atrophic gastritis (CAG), and evaluate the possible mechanisms.METHODS: Rats were administered with 60% alcohol or 2% salicylate sodium, 20 mmol/L deoxycholate sodium and 0.1% am... | ['Animals', 'Chronic Disease', 'Epidermal Growth Factor', 'ErbB Receptors', 'Gastric Mucosa', 'Gastrins', 'Gastritis, Atrophic', 'Immunohistochemistry', 'Male', 'Proto-Oncogene Proteins c-bcl-2', 'Rats', 'Rats, Sprague-Dawley', 'Tumor Suppressor Protein p53'] | 16,845,717 | [['B01.050'], ['C23.550.291.500'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320'... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Transforming growth factor-beta1 enhances the antifibrinolytic and prothrombotic state of growing endothelial cells in a cell cycle-specific manner. | Cell cycle-dependent modulation of protein expression may influence the balance of antithrombotic and prothrombotic properties of endothelial cells. In the present study, we examined the regulation of prothrombotic and antithrombotic molecules by transforming growth factor-beta1 (TGF-beta1) during distinct phases of th... | ['Cell Cycle', 'Cells, Cultured', 'Endothelial Cells', 'Endothelium, Vascular', 'Gene Expression Regulation', 'Humans', 'Plasminogen Activator Inhibitor 1', 'Thrombomodulin', 'Tissue Plasminogen Activator', 'Transforming Growth Factor beta', 'Transforming Growth Factor beta1', 'Urokinase-Type Plasminogen Activator'] | 16,571,780 | [['G04.144'], ['A11.251'], ['A11.436.275'], ['A07.015.700.500', 'A10.272.491.355'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.861.695.500', 'D12.776.124.125.640', 'D12.776.872.695.500', 'D23.119.832.500'], ['D12.776.395.550.625.800.800', 'D12.776.543.550.625.800.800', 'D12.776.543.750.705.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
International variation in management of screen-detected ductal carcinoma in situ of the breast. | BACKGROUND: Ductal carcinoma in situ (DCIS) incidence has grown with the implementation of screening and its detection varies across International Cancer Screening Network (ICSN) countries. The aim of this survey is to describe the management of screen-detected DCIS in ICSN countries and to evaluate the potential for t... | ['Aged', 'Breast Neoplasms', 'Carcinoma, Intraductal, Noninfiltrating', 'Early Detection of Cancer', 'Europe', 'Female', 'Humans', 'International Agencies', 'Japan', 'Lymph Node Excision', 'Mastectomy, Segmental', 'Middle Aged', 'Outcome Assessment, Health Care', 'Radiotherapy', 'United States'] | 25,149,183 | [['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['E01.390.500'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.514'], ['Z01.252.474.463', 'Z01.639.595'], ['E04.446'], ['E04.466.701'], ['M01.060.116.630... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Microalgae cultivation in sugarcane vinasse: Selection, growth and biochemical characterization. | Sugarcane ethanol is produced at large scale generating wastes that could be used for microalgae biomass production in a biorefinery strategy. In this study, forty microalgae strains were screened for growth in sugarcane vinasse at different concentrations. Two microalgae strains, Micractinium sp. Embrapa|LBA32 and C. ... | ['Biomass', 'Carbohydrates', 'Cell Culture Techniques', 'Ethanol', 'Microalgae', 'Photobioreactors', 'Saccharum', 'Waste Products'] | 28,061,395 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D09'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['D02.033.375'], ['B05.080.500.600.500'], ['E07.115.600', 'J01.897.120.115.600'], ['B01.650.940.800.575.912.250.822.835'], ['D20.944', 'N06.850.460.710']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Serum markers of hepatocyte death and apoptosis are non invasive biomarkers of severe fibrosis in patients with alcoholic liver disease. | BACKGROUND: Quantification of hepatocyte death is useful to evaluate the progression of alcoholic liver diseases. Our aims were to quantify and correlate the circulating levels of Cytokeratin 18 (CK18) and its caspases-generated fragment to disease severity in heavy alcoholics.METHODOLOGY/PRINCIPAL FINDINGS: CK18 and C... | ['Adult', 'Apoptosis', 'Biomarkers', 'Female', 'Hepatocytes', 'Humans', 'Liver Cirrhosis', 'Liver Diseases, Alcoholic', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Transforming Growth Factor beta', 'Tumor Necrosis Factor-alpha'] | 21,445,263 | [['M01.060.116'], ['G04.146.954.035'], ['D23.101'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['C06.552.645', 'C25.775.100.087.645'], ['M01.060.116.630'], ['E05.393.620.500'], ['D12.644.276.374.687', 'D12.644.276.954.775', 'D12.776.467.374.687', 'D12.776.467.9... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Divalent cation affinity sites in Paramecium aurelia. | Sites with high calcium affinity in Paramecium aurelia were identified by high calcium (5 mM) fixation and electron microscope methods. Electron-opaque deposits were observed on the cytoplasmic side of surface membranes, particularly at the basal regions of cilia and trichocyst-pellicle fusion sites. Deposits were also... | ['Animals', 'Barium', 'Binding Sites', 'Calcium', 'Cations, Divalent', 'Cell Membrane', 'Cilia', 'Electron Probe Microanalysis', 'Histocytochemistry', 'Magnesium', 'Manganese', 'Nickel', 'Paramecium', 'Strontium', 'Zinc'] | 1,262,398 | [['B01.050'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300.333'], ['A11.284.149'], ['A11.284.180.165'], ['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Calcium losses resulting from an acute bout of moderate-intensity exercise. | The purpose of this study was to compare daily calcium (Ca) losses in sweat (S) and urine (U) on an exercise day (E) with losses on the preceding day (i.e., a rest day) during which no exercise (NE) was performed. Ten healthy male volunteers (23.9 +/- 3.2 years) performed a single bout of moderate exercise (running at ... | ['Adult', 'Calcium', 'Calcium, Dietary', 'Exercise', 'Hot Temperature', 'Humans', 'Humidity', 'Male', 'Running', 'Sweat'] | 10,477,363 | [['M01.060.116'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.146.395'], ['G11.427.410.698.277', 'I03.350'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Free transplantation of skin onto the face]. | Basing on their experiences the authors describe principal technical methods of free transplantation of skin in different areas of the face. Their personal observations are used as illustrations. | ['Aged', 'Face', 'Female', 'Humans', 'Skin Transplantation'] | 11,837,169 | [['M01.060.116.100'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Respiratory mechanics and breathing pattern during and following maximal exercise. | We looked for evidence of changes in lung elastic recoil and of inspiratory muscle fatigue at maximal exercise in seven normal subjects. Esophageal pressure, flow, and volume were measured during spontaneous breathing at increasing levels of cycle exercise to maximum. Total lung capacity (TLC) was determined at rest an... | ['Adult', 'Biomechanical Phenomena', 'Heart Rate', 'Humans', 'Lung Compliance', 'Lung Volume Measurements', 'Male', 'Oxygen Consumption', 'Physical Exertion', 'Pressure', 'Respiration', 'Tidal Volume', 'Total Lung Capacity', 'Vital Capacity'] | 6,511,552 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.475', 'G09.772.540'], ['E01.370.386.700.485'], ['G03.680'], ['G11.427.683'], ['G01.374.715'], ['G09.772.705'], ['E01.370.386.700.485.750.900.350.750', 'G09.772... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
miR-200a/miR-141 and miR-205 upregulation might be associated with hormone receptor status and prognosis in endometrial carcinomas. | The aim of this study was to compare the clinicopathological significance of miR-200a/miR-141 and miR-205 expression in endometrioid carcinomas (ECs) versus nonendometrioid carcinomas (NECs) and to assess their correlation with hormone receptor status. miR-200a/miR-141 and miR-205 expression in 154 endometrial cancers ... | ['Adult', 'Aged', 'Carcinoma', 'Endometrial Neoplasms', 'Female', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'MicroRNAs', 'Middle Aged', 'Prognosis', 'Proportional Hazards Models', 'Real-Time Polymerase Chain Reaction', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Up-Regulation'] | 26,045,795 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Robust Association Tests for the Replication of Genome-Wide Association Studies. | In genome-wide association study (GWAS), robust genetic association tests such as maximum of three CATTs (MAX3), each corresponding to recessive, additive, and dominant genetic models, the minimum p value of Pearson's Chi-square test with 2 degrees of freedom, and CATT based on additive genetic model (MIN2), genetic mo... | ['DNA Replication', 'Genome', 'Genome-Wide Association Study', 'Models, Genetic'] | 26,345,547 | [['G02.111.225', 'G05.226'], ['G05.360.340'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['E05.599.395.397']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Significance of CCL2, CCL5 and CCR2 polymorphisms for adverse prognosis of Japanese encephalitis from an endemic population of India. | Japanese encephalitis (JE) is a major contributor for viral encephalitis in Asia. Vaccination programme has limited success for largely populated JE endemic countries like India and disease exposure is unavoidable. Involvement of chemokines and its co-receptors for adverse prognosis of JE have been documented both in v... | ['Adult', 'Chemokine CCL2', 'Chemokine CCL5', 'Cross-Sectional Studies', 'Encephalitis, Japanese', 'Endemic Diseases', 'Female', 'Follow-Up Studies', 'Genetic Association Studies', 'Humans', 'India', 'Male', 'Polymorphism, Single Nucleotide', 'Prognosis', 'Receptors, CCR2', 'Survival Analysis'] | 29,057,937 | [['M01.060.116'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D12.644.276.374.200.110.250', 'D12.776.467.374.200.110.250', 'D23.125.300.110.250', 'D23.469.200.110.250', 'D23.529.374.200.110.250'], ['E05.31... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Heteroclinic bifurcation in a ratio-dependent predator-prey system. | In this paper we study the heteroclinic bifurcation in a general ratio-dependent predator-prey system. Based on the results of heteroclinic loop obtained in [J. Math. Biol. 43(2001): 221-246], we give parametric conditions of the existence of the heteroclinic loop analytically and describe the heteroclinic bifurcation ... | ['Animals', 'Ecosystem', 'Models, Biological', 'Predatory Behavior', 'Systems Theory'] | 15,614,545 | [['B01.050'], ['G16.500.275.157', 'N06.230.124'], ['E05.599.395'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['H01.770.808']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Prostacyclin effect on blood pressure in pig with aortic obstruction. | Cardiovascular effects of infused prostacyclin (PGI2) were investigated in hypertensive anesthetized pigs in the steady state and at 1,2,3,4,5,10,15,20 and 30 min after the beginning of the infusion. PGI2 were perfused at the rate of 2 microgram/Kg/min for 4 min before and after vagosympathectomy. We measured the mean ... | ['Animals', 'Aorta', 'Blood Pressure', 'Constriction', 'Epoprostenol', 'Heart Rate', 'Prostaglandins', 'Pulmonary Wedge Pressure', 'Swine', 'Sympathectomy', 'Vagotomy'] | 7,031,726 | [['B01.050'], ['A07.015.114.056'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.225'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['G09.330.380.076.695'], ['B01.050.150.900.649.313.500.880'], ['E04.525.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sargassum serratifolium | Osteoarthritis (OA) is a degenerative joint disease that is characterized by irreversible articular cartilage destruction by inflammatory reaction. Among inflammatory stimuli, interleukin-1â (IL-1â) is known to play a crucial role in OA pathogenesis by stimulating several mediators that contribute to cartilage degradat... | ['Animals', 'Anti-Inflammatory Agents', 'Antioxidants', 'Cell Line', 'Cells, Cultured', 'Chondrocytes', 'Humans', 'Inflammation', 'Interleukin-1beta', 'Male', 'NF-kappa B', 'Osteoarthritis', 'Oxidative Stress', 'Phosphatidylinositol 3-Kinases', 'Plant Extracts', 'Proto-Oncogene Proteins c-akt', 'Rats', 'Rats, Sprague-D... | 30,087,236 | [['B01.050'], ['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A11.251.210'], ['A11.251'], ['A11.329.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.37... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Germ cell line during the seasonal sexual rest of clams: finding niches of cells for gonad renewal. | Reconstitution and renewal of tissues are key topics in developmental biology. In this brief work, we analyzed the wintry spent phase of the reproductive cycle in the Manila clam Ruditapes philippinarum (Bivalvia, Veneridae) in order to study the gonad rebuilding that in this species occurs at the beginning of the warm... | ['Animals', 'Biological Clocks', 'Bivalvia', 'Cell Line', 'Germ Cells', 'Gonads', 'Seasons', 'Sexual Behavior, Animal'] | 28,875,375 | [['B01.050'], ['G07.180.562.094'], ['B01.050.500.644.080'], ['A11.251.210'], ['A05.360.490', 'A11.497'], ['A05.360.576', 'A06.300.312'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['F01.145.113.252.748']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Towards a proteomic map of Lactococcus lactis NCDO 763. | Lactococcus lactis is a widely used bacteria in dairy industry, specially in cheese ripening. Numerous lactococcal enzymes and proteins are involved in this process. Proteomics makes it possible to deal with a high number of proteins and identify modification of their patterns in two-dimensional (2-D) gels. However, an... | ['Bacterial Proteins', 'Electrophoresis, Gel, Two-Dimensional', 'Lactococcus lactis', 'Peptide Mapping', 'Proteome'] | 10,939,470 | [['D12.776.097'], ['E05.196.401.250', 'E05.301.300.230'], ['B03.353.750.737.500.400', 'B03.510.400.800.500.400', 'B03.510.550.737.500.400'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['D12.776.817']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
International practices in the dietary management of fructose 1-6 biphosphatase deficiency. | BACKGROUND: In fructose 1,6 bisphosphatase (FBPase) deficiency, management aims to prevent hypoglycaemia and lactic acidosis by avoiding prolonged fasting, particularly during febrile illness. Although the need for an emergency regimen to avoid metabolic decompensation is well established at times of illness, there is ... | ['Acidosis, Lactic', 'Cross-Sectional Studies', 'Dietary Carbohydrates', 'Dietary Supplements', 'Fasting', 'Fructose-1,6-Diphosphatase Deficiency', 'Humans', 'Hypoglycemia', 'Surveys and Questionnaires'] | 29,370,874 | [['C18.452.076.176.180'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['G07.203.300.456', 'J02.500.456'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['C16.320.565.202.251.221', 'C18.452.648.202.251.221'], ['B01.050... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Ultrasonography and articular cartilage defects in the knee: an in vitro evaluation of the accuracy of cartilage thickness and defect size assessment. | The purpose of this cadaver study was to test the accuracy of ultrasonography in measuring cartilage thickness, and the extent and depth of induced cartilage defects on the medial and lateral femoral condyles of the knee in a clinically relevant setting. With the knees maximally flexed, cartilage thickness was measured... | ['Aged', 'Body Weights and Measures', 'Cadaver', 'Cartilage Diseases', 'Cartilage, Articular', 'Humans', 'Knee Joint', 'Ultrasonography'] | 15,022,038 | [['M01.060.116.100'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['C23.550.260.224'], ['C05.182', 'C17.300.182'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['E01.370.350.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acclimation to the growth temperature and thermosensitivity of photosystem II in a mesophilic cyanobacterium, Synechocystis sp. PCC6803. | Differences in the temperature dependence and thermosensitivities of PSII activities in Synechocystis sp. PCC6803 grown at 25 and 35 degrees C were studied. Hill reactions in cells, thylakoid membranes and purified PSII core complexes were measured at high temperatures or at their growth temperatures after high-tempera... | ['Acclimatization', 'Cyanobacteria', 'Cytosol', 'Electrons', 'Hydrogen-Ion Concentration', 'Oxygen', 'Photosystem II Protein Complex', 'Plastoquinone', 'Temperature', 'Thylakoids'] | 17,056,616 | [['G07.025.133', 'G16.012.500.133'], ['B03.280', 'B03.440.475.100'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G01.249.335', 'G01.358.500.750'], ['G02.300'], ['D01.268.185.550', 'D01.362.670'], ['D05.500.562.488.750', 'D08.811.600.710.750', 'D12.776.543.930.500.750', 'D12.776.765.199.750.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of an anti-tumor necrosis factor therapeutic in a mouse model of Niemann-Pick C liver disease. | BACKGROUND: Niemann-Pick type C (NPC) disease is a lysosomal storage disease characterized by the accumulation of cholesterol and glycosphingolipids. The majority of NPC patients die in their teen years due to progressive neurodegeneration; however, half of NPC patients also suffer from cholestasis, prolonged jaundice,... | ['Animals', 'Antibodies, Monoclonal', 'Apoptosis', 'Cholesterol', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Female', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Lipid Metabolism', 'Liver', 'Mice', 'Mice, Inbred C57BL', 'Niemann-Pick Disease, Type C', 'Proteins', 'Tumor Necrosis Factor-a... | 20,886,067 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.146.954.035'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.988.400.11... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Companion-diagnostic testing limited to KRAS codons 12 and 13 misses 17% of potentially relevant RAS mutations in colorectal cancer. | BACKGROUND: KRAS codons 12 and 13 mutations are commonly used to identify colorectal carcinoma (CRC) patients who are unlikely to benefit from anti-EGFR therapy. However, humans have four different homologous RAS proteins and no routine screening is performed for the other mutation sites. Non-screened mutations may sti... | ['Antibodies, Monoclonal', 'Carcinoma', 'Codon', 'Colorectal Neoplasms', 'ErbB Receptors', 'Gene Expression', 'Genetic Testing', 'Humans', 'Mutation', 'Paraffin', 'Polymerase Chain Reaction', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins p21(ras)', 'Sensitivity and Specificity', 'Sequence Analysis, DNA', 'Tissue ... | 23,832,066 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C04.557.470.200'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of neodymium: YAG capsulotomy on contrast sensitivity and the evaluation of methods for its assessment. | OBJECTIVE: To determine the most appropriate method for measuring the effect on contrast sensitivity of neodymium:YAG (Nd:YAG) posterior capsulotomy for early posterior capsular opacification (PCO).DESIGN: Prospective comparison of five different methods for luminous contrast sensitivity testing in patients undergoing ... | ['Aged', 'Aged, 80 and over', 'Cataract', 'Cataract Extraction', 'Contrast Sensitivity', 'Humans', 'Laser Therapy', 'Lens Capsule, Crystalline', 'Middle Aged', 'Prospective Studies', 'Vision Tests', 'Visual Acuity'] | 10,201,590 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.510.245'], ['E04.540.825.249'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['A09.371.060.500.155'], ['M01.060.11... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The development of an audit technique to assess the quality of safety barrier management. | This paper describes the development of a management model to control barriers devised to prevent major hazard scenarios. Additionally, an audit technique is explained that assesses the quality of such a management system. The final purpose of the audit technique is to quantify those aspects of the management system th... | ['Accidents, Occupational', 'Causality', 'Chemical Industry', 'Computers', 'Containment of Biohazards', 'Disaster Planning', 'Environmental Exposure', 'Europe', 'European Union', 'Guidelines as Topic', 'Hazardous Substances', 'Humans', 'Management Audit', 'Risk Assessment', 'Safety Management', 'Software'] | 16,111,813 | [['N06.850.135.240'], ['N05.715.350.200', 'N06.850.490.625'], ['J01.576.655.437'], ['L01.224.230.260'], ['E05.235', 'N06.850.135.060.075.249'], ['N06.230.100.035'], ['N06.850.460.350'], ['Z01.542'], ['I01.615.500.475'], ['N04.761.700.350', 'N05.700.350'], ['D27.888.426'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases. | BACKGROUND: Periapical lesions are thought to be the result of a local inflammatory response mediated by inflammatory cell infiltration and production of inflammatory mediators. Although chemokines are strongly implicated in the migration and activation of leukocytes in different inflammatory diseases and experimental ... | ['Adult', 'Aged', 'Chemokine CCL2', 'Chemokine CCL3', 'Chemokine CCL4', 'Chemokine CCL5', 'Chemokine CXCL10', 'Chemokines', 'Chemokines, CC', 'Chemokines, CXC', 'Chemotaxis, Leukocyte', 'Gingiva', 'Humans', 'Interleukin-8', 'Leukocytes', 'Macrophage Inflammatory Proteins', 'Middle Aged', 'Periapical Granuloma', 'Periap... | 16,101,967 | [['M01.060.116'], ['M01.060.116.100'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D12.644.276.374.200.110.150', 'D12.644.276.374.200.600.150', 'D12.776.467.374.200.110.150', 'D12.776.467.374.200.600.150',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Retroperitoneoscopic partial nephrectomy in children: a multicentric international comparative study between lateral versus prone approach. | BACKGROUND: Very limited informations are currently available about the best approach to perform retroperitoneoscopic surgery. This multicentric international study aimed to compare the outcome of lateral versus prone approach for retroperitoneoscopic partial nephrectomy (RPN) in children.METHODS: The records of 164 pa... | ['Child, Preschool', 'Conversion to Open Surgery', 'Female', 'Humans', 'Incidence', 'Internationality', 'Intraoperative Complications', 'Laparoscopy', 'Male', 'Nephrectomy', 'Postoperative Complications', 'Reoperation', 'Retroperitoneal Space', 'Retrospective Studies', 'Treatment Outcome'] | 30,006,841 | [['M01.060.406.448'], ['E04.502.250.155'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['I01.615'], ['C23.550.505'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E04.950.774.435'], ['C23.550.767'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Validation of the Italian version of the Coma Recovery Scale-Revised (CRS-R). | PRIMARY OBJECTIVE: To validate the Italian version of the Coma Recovery Scale-Revised (CRS-R).METHODS: Two observers applied the Italian version of the CRS-R to selected patients. On day 1, observer A and B independently scored each patient; the comparison of their observations was used to evaluate inter-observer agree... | ['Brain Damage, Chronic', 'Coma', 'Consciousness', 'Female', 'Humans', 'Italy', 'Language', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Observer Variation', 'Recovery of Function', 'Trauma Severity Indices'] | 21,401,371 | [['C10.228.140.140'], ['C10.597.606.358.800.200', 'C23.888.592.604.359.800.200'], ['F02.463.188.409', 'F02.830.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['F01.145.209.399', 'L01.559'], ['M01.060.116.630'], ['F04.711.513'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Hairless modulates ligand-dependent activation of the vitamin D receptor-retinoid X receptor heterodimer. | The active form of vitamin D, 1á,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], binds to the vitamin D receptor (VDR) and regulates various physiological and pharmacological processes. Secondary bile acids, such as lithocholic acid (LCA), also act as endogenous VDR ligands. The molecular basis of ligand-selective VDR acti... | ['Calcitriol', 'Cell Line', 'Co-Repressor Proteins', 'Cyclic AMP', 'HEK293 Cells', 'Humans', 'Ligands', 'Lithocholic Acid', 'RNA, Messenger', 'Receptors, Calcitriol', 'Retinoid X Receptors', 'Steroid Hydroxylases', 'Transcription Factors', 'Transcriptional Activation', 'Vitamin D3 24-Hydroxylase'] | 22,466,564 | [['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['A11.251.210'], ['D12.776.930.780.625'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A11.251.210.172.750', 'A11.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impedimetric investigation of dual electrical properties of reduced graphene-oxide-based biosensors in the detection of dopamine. | Because of the properties of high charge mobility, large detection area and chemical stability of graphene, it has been applied in many biomedical applications. Graphene oxide (GO) with abundant oxygenated functional groups is easily to form an aqueous suspension by sonication. Here, the exposed areas on the patterned-... | ['Biosensing Techniques', 'Dopamine', 'Graphite', 'Oxides'] | 29,060,798 | [['E05.601.043'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D01.268.150.300', 'D01.578.300'], ['D01.248.497.158.685', 'D01.650.550']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tryptase from rat skin: purification and properties. | Tryptase was purified 13,000-fold to apparent homogeneity from rat skin. The two-step procedure involved ammonium sulfate fractionation of the initial extract followed by combined sequential affinity chromatography on agarose-glycyl-glycyl-p-aminobenzamidine and concanavalin A-agarose. The purified enzyme had a specifi... | ['Amino Acid Sequence', 'Animals', 'Chromatography, Affinity', 'Electrophoresis, Polyacrylamide Gel', 'Endopeptidases', 'Hormones', 'Indicators and Reagents', 'Male', 'Molecular Sequence Data', 'Molecular Weight', 'Peptide Hydrolases', 'Peptides', 'Rats', 'Rats, Inbred Strains', 'Sequence Homology, Nucleic Acid', 'Skin... | 2,036,367 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.181.400.170'], ['E05.196.401.402', 'E05.301.300.319'], ['D08.811.277.656.300'], ['D06.472', 'D27.505.696.399.472'], ['D27.720.470.410'], ['L01.453.245.667'], ['G02.494'], ['D08.811.277.656'], ['D12.644'], ['B01.050.150.900.649.313.992.635.505.700'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reproducibility and interobserver variability of systolic blood flow velocity and 3D wall shear stress derived from 4D flow MRI in the healthy aorta. | PURPOSE: To investigate the reproducibility and interobserver variability of 3D aortic velocity vector fields and wall shear stress (WSS) averaged over five systolic timeframes derived from noncontrast 4D flow magnetic resonance imaging (MRI).MATERIALS AND METHODS: Fourteen controls underwent test-retest 4D flow MRI ex... | ['Adult', 'Aged', 'Aorta', 'Blood Flow Velocity', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged', 'Observer Variation', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Shear Strength', 'Systole', 'Young A... | 26,140,480 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.056'], ['E01.370.370.130', 'G09.330.380.630.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['M01.06... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Potentiation of DNA-adduct formation and cytotoxicity of platinum-containing drugs by low pH. | The low interstitial pH of tumor tissue is an important modulator of various anti-tumor modalities. In order to explore the optimal conditions for the potentiating action of low pH on the cytotoxic activities of cis- and carboplatin, we have investigated the temporal aspects of drug activity and pH modulation in L1210 ... | ['Animals', 'Biological Transport', 'Carboplatin', 'Cisplatin', 'Cytoplasm', 'DNA', 'DNA Damage', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Leukemia L1210', 'Mice', 'Time Factors', 'Tumor Cells, Cultured'] | 8,478,143 | [['B01.050'], ['G03.143'], ['D02.257.125'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['A11.284.430.214'], ['D13.444.308'], ['G05.200'], ['G02.300'], ['E05.481'], ['C04.557.337.372.594', 'C04.619.531.594'], ['B01.050.150.900.649.313.992.635.505.500'], ['G01.910.857'], ['A11.251.860']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of transcranial direct current stimulation of the motor cortex on prefrontal cortex activation during a neuromuscular fatigue task: an fNIRS study. | This study investigated whether manipulation of motor cortex excitability by transcranial direct current stimulation (tDCS) modulates neuromuscular fatigue and functional near-infrared spectroscopy (fNIRS)-derived prefrontal cortex (PFC) activation. Fifteen healthy men (27.7 ± 8.4 years) underwent anodal (2 mA, 10 min)... | ['Adult', 'Elbow', 'Fatigue', 'Hemoglobins', 'Humans', 'Isometric Contraction', 'Male', 'Motor Cortex', 'Neuromuscular Junction', 'Oxyhemoglobins', 'Prefrontal Cortex', 'Psychomotor Performance', 'Spectroscopy, Near-Infrared', 'Transcranial Magnetic Stimulation'] | 23,852,479 | [['M01.060.116'], ['A01.378.800.420'], ['C23.888.369'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['A08.800.550.550.550', 'A08.850.550.550', 'A11.284.149.165.420.780.55... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Fluorescence in situ hybridization detection of peripheral lymphocyte and ultrastructural study of the testicular tissue in a 48,XXYY syndrome patient]. | OBJECTIVE: To investigate the pathogenesis of male sterility in 48,XXYY syndrome patient.METHODS: The peripheral lymphocyte was detected by dual-color fluorescence in situ hybridization. The bioptic testicular tissues were pathologically sectioned and ultra-thin sections were examined by electron-microscopy.RESULTS: Th... | ['Adult', 'Chromosomes, Human, X', 'Chromosomes, Human, Y', 'Humans', 'In Situ Hybridization, Fluorescence', 'Infertility, Male', 'Lymphocytes', 'Male', 'Microscopy, Electron', 'Sex Chromosome Aberrations', 'Testis'] | 14,556,200 | [['M01.060.116'], ['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Validity study of the Moral Judgment Test in Physical Education: development and preliminary validation. | Teaching ethical behavior is an aspect of physical education. The purpose of the study was to present the construction and to estimate validity of a test which assesses physical education students' moral judgment, the Moral Judgment Test in Physical Education. The sample comprised 281 male and female participants (95 i... | ['Adolescent', 'Attitude', 'Child', 'Female', 'Humans', 'Judgment', 'Male', 'Models, Psychological', 'Moral Development', 'Morals', 'Physical Education and Training', 'Psychometrics', 'Reproducibility of Results', 'Sports', 'Students', 'Surveys and Questionnaires', 'Teaching'] | 18,459,355 | [['M01.060.057'], ['F01.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['E05.599.695'], ['F01.752.747.616', 'F01.829.500.679', 'K01.752.566.739'], ['F01.829.500', 'K01.752.566'], ['I02.233.543'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
CD40 stimulation induces vincristine resistance via AKT activation and MRP1 expression in a human multiple myeloma cell line. | Various co-stimulatory receptors are expressed in multiple myeloma (MM) both in immune microenvironment and in the tumor microenvironment in vivo. In relapsed human MM, these receptors are known to increase cell proliferation and induce conventional drug resistance. However, the mechanism of drug resistance induced via... | ['Antineoplastic Agents, Phytogenic', 'CD40 Antigens', 'CD40 Ligand', 'Cell Line, Tumor', 'Drug Resistance, Neoplasm', 'Gene Expression Regulation', 'Humans', 'Multidrug Resistance-Associated Proteins', 'Multiple Myeloma', 'Proto-Oncogene Proteins c-akt', 'Signal Transduction', 'Vincristine'] | 22,445,357 | [['D27.505.954.248.179'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101.100.150.140'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.543.550.198', 'D23.529.374.750.124'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.984.395']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Negative-pressure wound therapy: a hemostatic adjunct for control of coagulopathic hemorrhage in large soft tissue wounds. | BACKGROUND: Negative-pressure wound therapy has been commonly used for treating chronic wounds and recently applied for treatment of traumatic wounds. We investigated the potential hemostatic benefit of negative-pressure wound therapy for control of refractory hemorrhage in a soft tissue wound model in swine.METHODS: C... | ['Animals', 'Blast Injuries', 'Blood Coagulation Disorders', 'Disease Models, Animal', 'Explosions', 'Hemorrhage', 'Hemostatic Techniques', 'Male', 'Negative-Pressure Wound Therapy', 'Soft Tissue Injuries', 'Swine'] | 23,117,379 | [['B01.050'], ['C26.120.126'], ['C15.378.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['N06.230.208'], ['C23.550.414'], ['E02.520'], ['E02.309.610', 'E04.237.444', 'E04.987.550'], ['C26.808'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Restriction mapping of DNA of temperate Rhizobium meliloti phage 16-3: comparison of genetic and physical maps indicates a long, genetically silent chromosomal arm. | The complete restriction map of DNA (61.57 Kb) of temperate Rhizobium meliloti phage 16-3 has been constructed for enzymes BglII, HindIII, HpaI, KpnI, and a partial map for EcoRI. The strategy employed for mapping included the analysis of double, triple and partial digests; comparison of wild type and deletion mutants;... | ['Bacteriophages', 'Chromosome Mapping', 'DNA Restriction Enzymes', 'DNA, Viral', 'Electrophoresis, Agar Gel', 'Genes, Viral', 'Molecular Weight', 'Rhizobium'] | 293,461 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of ROCK2 expression protects against methamphetamine-induced neurotoxicity in PC12 cells. | Methamphetamine is a type of psychoactive drug. It is well known that neurotoxicity caused by Methamphetamine(METH) can damage the nervous system and lead to apoptosis and cell loss of dopaminergic neurons. ROCK2 is a prominent target for gene therapy because its inhibition has proved to have a protective effect in var... | ['Animals', 'Apoptosis', 'Methamphetamine', 'Neurons', 'PC12 Cells', 'Rats', 'rho-Associated Kinases'] | 23,954,743 | [['B01.050'], ['G04.146.954.035'], ['D02.092.471.683.152.619'], ['A08.675', 'A11.671'], ['A11.251.210.190.750', 'A11.251.860.180.750', 'A11.299.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['D08.811.913.696.620.682.700.814', 'D12.644.360.590', 'D12.776.476.595']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic screening of wine-related enzymes in Lactobacillus species isolated from South African wines. | AIMS: The objective of this study was to investigate the presence of genes coding for enzymes of oenological relevance in wine Lactobacillus strains isolated from South African grape and wine samples during the 2001 and 2002 harvest seasons.METHODS AND RESULTS: A total of 120 wine lactobacilli isolates belonging to Lac... | ['Amino Acid Sequence', 'Enzymes', 'Lactobacillus', 'Sequence Alignment', 'Vitis', 'Wine', 'beta-Glucosidase'] | 19,793,136 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['E05.393.751'], ['B01.650.940.800.575.912.250.965.500'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02.200.100.900', 'J02.350.887'], ['D08.811.277.450.420.200.100']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Ornithine decarboxylase: haplotype structure and trait associations in White Leghorn chickens. | Sequence analysis of 4,230 bp of the 3' end of the ornithine decarboxylase gene of 20 chickens from a noninbred White Leghorn strain revealed a total of 62 polymorphisms. Of these 61% were transitions, 24% were transversions, and 16% were deletions or insertions. Despite the high number of polymorphisms, only 3 haploty... | ['Animals', 'Body Weight', 'Chickens', 'DNA Primers', 'Female', 'Genotype', 'Haplotypes', 'Male', 'Ornithine Decarboxylase', 'Polymorphism, Restriction Fragment Length', 'Quantitative Trait Loci', 'Sequence Analysis, DNA', 'Sexual Maturation'] | 15,384,901 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.380'], ['G05.380.360'], ['D08.811.520.224.125.425'], ['G05.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a tightly regulated and highly inducible ecdysone receptor gene switch for plants through the use of retinoid X receptor chimeras. | Chemical inducible gene regulation systems provide essential tools for the precise regulation of transgene expression in plants and animals. Recent development of a two-hybrid ecdysone receptor (EcR) gene regulation system has solved some of the drawbacks that were associated with the monopartate gene switch. To furthe... | ['Arabidopsis', 'DNA', 'Gene Expression Regulation', 'Genetic Techniques', 'Humans', 'Hydrazines', 'Juvenile Hormones', 'Ligands', 'Models, Genetic', 'Plants, Genetically Modified', 'Protoplasts', 'Receptors, Steroid', 'Recombinant Fusion Proteins', 'Retinoid X Receptors', 'Tobacco', 'Transgenes', 'Two-Hybrid System Te... | 17,139,530 | [['B01.650.940.800.575.912.250.157.100'], ['D13.444.308'], ['G05.308'], ['E05.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442'], ['D06.472.445.573.666'], ['D27.720.470.480'], ['E05.599.395.397'], ['B01.650.520', 'B05.620.600'], ['A11.789'], ['D12.776.826.750', 'D12.776.930.778'], ['D12.776.828.300'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Opposite effects on tumor growth depending on dose of Achyranthes bidentata polysaccharides in C57BL/6 mice. | We report here the investigation on the effects of Achyranthes bidentata polysaccharides (ABPS) against Lewis lung cancer (LLC) in C57BL/6 mice. Depending on its doses administered in vivo, ABPS was shown to have inhibitory as well as stimulative effects on tumor growth in LLC-bearing C57BL/6 mice. ABPS at low dose cou... | ['Achyranthes', 'Animals', 'Antineoplastic Agents, Phytogenic', 'Carcinoma, Lewis Lung', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Survival', 'Cytokines', 'Dose-Response Relationship, Drug', 'Female', 'Lung Neoplasms', 'Mice', 'Mice, Inbred C57BL', 'Organ Size', 'Polysaccharides', 'RNA, Messenger', 'Reverse Transcriptase... | 17,386,404 | [['B01.650.940.800.575.912.250.198.500.100.100'], ['B01.050'], ['D27.505.954.248.179'], ['C04.557.470.200.280', 'C04.619.230'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'], ['C04.588.894.797.520', 'C08.38... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of morphine on metabolism of dopamine and serotonin in brains of alcohol-preferring AA and alcohol-avoiding ANA rats. | Morphine induces a larger locomotor stimulation in the alcohol-preferring AA rats than in the alcohol-avoiding ANA rats. We have now studied the acute effects of morphine (1 and 3 mg/kg) on metabolism of dopamine and serotonin (5-HT) in the dorsal and ventral striatum of the AA and ANA rats. The basal level of dopamine... | ['Alcohol Drinking', 'Analgesics, Opioid', 'Animals', 'Caudate Nucleus', 'Dopamine', 'Morphine', 'Nucleus Accumbens', 'Olfactory Pathways', 'Rats', 'Serotonin'] | 10,386,658 | [['F01.145.317.269'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050'], ['A08.186.211.200.885.287.249.487.550.184'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D03.132.577.249.562.571', 'D0... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preoperative transarterial embolization of hypervascular vertebral tumor with permanent particles. | OBJECTIVE: To evaluate the safety and value of preoperative transarterial embolization of hypervascular vertebral tumors.METHODS: Sixteen patients with hypervascular vertebral tumors underwent transarterial embolization before surgery. The lesions were located between the middle cervical and lower lumbar spine. Forty-o... | ['Adolescent', 'Adult', 'Arteries', 'Embolization, Therapeutic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Spinal Neoplasms'] | 12,609,088 | [['M01.060.057'], ['M01.060.116'], ['A07.015.114'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.5... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Screening for cervical cancer in the county of Funen. Status of 25 years of development and experiences]. | INTRODUCTION: Since 1979 screening against cervical cancer has been conducted in the County of Funen. In the period 1979-1988 the screening against cervical cancer was opportunistic, where women aged 25-55 years had a PAP-smear taken once a year by their GP or gynaecologists at the hospitals. In this period the coverag... | ['Adult', 'Denmark', 'Family Practice', 'Female', 'Humans', 'Incidence', 'Mass Screening', 'Middle Aged', 'Papanicolaou Test', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 16,768,956 | [['M01.060.116'], ['Z01.542.816.124'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
[The so-called preventive house call. Forestalling nursing home admission]. | In view of the increasing numbers of elderly citizens in the general population, there is a need to ensure that they receive medical care within a setting of independence preservation and, wherever possible, within the domestic environment. Preventive house calls can contribute greatly to efforts made to achieve this a... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Chronic Disease', 'Disability Evaluation', 'Forecasting', 'Frail Elderly', 'Germany', 'House Calls', 'Humans', 'Nursing Homes', 'Patient Admission', 'Population Dynamics', 'Risk Assessment'] | 12,808,820 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.291.500'], ['E01.370.400'], ['I01.320'], ['M01.060.116.100.540'], ['Z01.542.315'], ['N04.452.758.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.825.610'], ['E02.760.400.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Diffusion-weighted MRI of epithelial ovarian cancers: correlation of apparent diffusion coefficient values with histologic grade and surgical stage. | OBJECTIVE: The purpose of this article is to correlate the apparent diffusion coefficient (ADC) values of epithelial ovarian cancers with histologic grade and surgical stage.MATERIALS AND METHODS: We enrolled 43 patients with pathologically proven epithelial ovarian cancers for this retrospective study. All patients un... | ['Adult', 'Aged', 'Biomarkers', 'Carcinoma, Ovarian Epithelial', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Staging', 'Neoplasms, Glandular and Epithelial', 'Ovarian Neoplasms', 'ROC Curve', 'Retrospective Studies', 'Sensitivity and Specificity'] | 25,623,826 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['C04.557.470.200.295', 'C04.588.322.455.199', 'C13.351.500.056.630.705.350', 'C13.351.937.418.685.350', 'C19.344.410.199', 'C19.391.630.705.350'], ['E01.370.350.825.500.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.612'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The changes of beta-glucuronidase in rabbit model with calcium bilirubinate stone]. | The aim of the present study is to determine the beta-glucuronidase changes in bile and hepatobiliary tissue of rabbit model having pigment gallstone by means of biochemical and enzymehistochemical assay methods. The result showed both of the bacterial and non-bacterial beta-glucuronidase take part in the course of pig... | ['Animals', 'Bile', 'Bilirubin', 'Calcium', 'Cholelithiasis', 'Escherichia coli', 'Female', 'Glucuronidase', 'Liver', 'Male', 'Rabbits'] | 2,202,652 | [['B01.050'], ['A12.200.087'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C06.130.409'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.450.426'], ['A03.620'], ['B01.050.150.900.649... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Paraventricular nucleus mediates pressor response to noradrenaline injection into the dorsal periaqueductal gray area. | The dorsal periaqueductal gray area (dPAG) is involved in cardiovascular modulation. In a previous study, we reported that noradrenaline (NA) microinjection into the dPAG of rats caused pressor response that was mediated by vasopressin release. Vasopressin is synthesized by magnocellular neurons in the hypothalamic par... | ['Animals', 'Antimutagenic Agents', 'Autonomic Pathways', 'Biotin', 'Blood Pressure', 'Cobalt', 'Dextrans', 'Male', 'Microinjections', 'Neural Pathways', 'Neuronal Tract-Tracers', 'Norepinephrine', 'Paraventricular Hypothalamic Nucleus', 'Periaqueductal Gray', 'Presynaptic Terminals', 'Rats', 'Rats, Wistar', 'Reflex', ... | 19,564,136 | [['B01.050'], ['D27.505.696.706.080', 'D27.720.799.042'], ['A08.800.050.050', 'A08.800.800.060'], ['D03.383.129.308.080', 'D08.211.096'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['D05.750.078.562.272', 'D09.698.365.272'], ['E02.319.267.530.690', 'E05.591.57... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thalidomide inhibits epidermal growth factor-induced cell growth in mouse and human monocytic leukemia cells via Ras inactivation. | The effect of thalidomide on epidermal growth factor (EGF)-induced cell growth was examined. Thalidomide inhibited EGF-induced cell growth in mouse and human monocytic leukemia cells, RAW 264.7, U937 and THP-1. Thalidomide inhibited EGF-induced phosphorylation of extracellular signal regulated kinase (ERK) 1/2, but not... | ['Angiogenesis Inhibitors', 'Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Proliferation', 'Enzyme Activation', 'Epidermal Growth Factor', 'ErbB Receptors', 'Humans', 'Leukemia', 'Mice', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Monocytes', 'Phosphorylation', 'Thalidomi... | 18,662,673 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.263', 'G03.328'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D08.811.91... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation between biological state markers of alcohol abuse and severity of alcohol dependence syndrome. | Data on the correlation between the degree of severity of the alcohol dependence syndrome, as evaluated through the Short Alcohol Dependence Data (SADD) questionnaire, and alterations of four biological state markers of alcohol abuse, namely gamma-glutamyltransferase (GGT), glutamate pyruvate transaminase (SGPT), gluta... | ['Adult', 'Alanine Transaminase', 'Alcoholism', 'Aspartate Aminotransferases', 'Erythrocyte Volume', 'Ethanol', 'Female', 'Humans', 'Male', 'Middle Aged', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'gamma-Glutamyltransferase'] | 2,883,983 | [['M01.060.116'], ['D08.811.913.477.700.100'], ['C25.775.100.250', 'F03.900.100.350'], ['D08.811.913.477.700.225'], ['G09.188.130.370', 'G09.330.380.092.370'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C25.775', 'F03.900'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Formation of Nanocomplexes between Carboxymethyl Inulin and Bovine Serum Albumin via pH-Induced Electrostatic Interaction. | As a functional polysaccharide, inulin was carboxymethylated and it formed nanocomplexes with bovine serum albumin (BSA). The success of obtaining carboxymethyl inulin (CMI) was confirmed by a combination of Fourier transform Infrared (FT-IR), Raman spectroscopy, gel permeation chromatography (GPC), and titration. The ... | ['Animals', 'Calorimetry', 'Cattle', 'Hydrogen-Ion Concentration', 'Inulin', 'Molecular Structure', 'Multiprotein Complexes', 'Nanocomposites', 'Serum Albumin, Bovine', 'Spectrum Analysis', 'Static Electricity', 'Thermodynamics'] | 31,443,488 | [['B01.050'], ['E05.196.131'], ['B01.050.150.900.649.313.500.380.271'], ['G02.300'], ['D05.750.078.562.855.750', 'D09.301.915.750', 'D09.698.350.500', 'D09.698.365.855.750'], ['G02.111.570', 'G02.466'], ['D05.500'], ['J01.637.512.150'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['E05.196.867'], ['G01.358.500.249.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A taxonomy for homework used by mental health case managers when working with individuals diagnosed with severe mental illness. | A survey was completed by 122 case managers describing the types of homework assignments commonly used with individuals diagnosed with severe mental illness (SMI). Homework types were categorized using a 12-item homework description taxonomy and in relation to the 22 domains of the Camberwell Assessment of Need (CAN). ... | ['Activities of Daily Living', 'Australia', 'Behavior Therapy', 'Case Management', 'Community Mental Health Services', 'Data Collection', 'Female', 'Humans', 'Hygiene', 'Male', 'Mental Disorders', 'Needs Assessment', 'Psychotic Disorders', 'Reproducibility of Results', 'Schizophrenia', 'Severity of Illness Index', 'Str... | 17,619,146 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['Z01.639.100', 'Z01.678.100.373'], ['F04.754.137'], ['N04.590.233.624.250'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Dermoscopic features of idiopathic facial aseptic granuloma. | Idiopathic facial aseptic granuloma is a recently described condition with defined clinical features, natural history, and underlying histopathologic findings. Several reports have recently described the potential diagnostic usefulness of ultrasound findings in idiopathic facial aseptic granuloma. We describe herein th... | ['Child', 'Dermoscopy', 'Diagnosis, Differential', 'Facial Dermatoses', 'Female', 'Granuloma', 'Humans', 'Skin', 'Ultrasonography'] | 29,962,067 | [['M01.060.406'], ['E01.370.350.515.277.250', 'E05.595.185.250'], ['E01.171'], ['C17.800.271'], ['C15.604.515.292', 'C23.550.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A17.815'], ['E01.370.350.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tear exchangeable limbal rigid contact lens for ocular sequelae resulting from Stevens-Johnson syndrome or toxic epidermal necrolysis. | PURPOSE: To evaluate the therapeutic benefits of tear-exchangeable, limbal, rigid contact lenses (limbal CLs) in patients with Stevens-Johnson syndrome- or toxic epidermal necrolysis-associated ocular sequelae.DESIGN: Noncomparative, retrospective, interventional case series.METHODS: We enrolled 53 eyes of 42 patients ... | ['Adult', 'Aged', 'Contact Lenses', 'Corneal Diseases', 'Equipment Design', 'Female', 'Follow-Up Studies', 'Humans', 'Limbus Corneae', 'Male', 'Middle Aged', 'Quality of Life', 'Retrospective Studies', 'Stevens-Johnson Syndrome', 'Surveys and Questionnaires', 'Tears', 'Time Factors', 'Visual Acuity'] | 25,036,881 | [['M01.060.116'], ['M01.060.116.100'], ['E07.632.500.276'], ['C11.204'], ['E05.320'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.217.659'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Ground substrate affects activity budgets and hair loss in outdoor captive groups of rhesus macaques (Macaca mulatta). | How the captive environment influences the behavior of animals is relevant to the well-being of captive animals. Captivity diverges from the natural environment in many ways, and one goal of enrichment practices is to encourage species-typical behavior in these unnatural environments. This study investigated the influe... | ['Animals', 'Animals, Laboratory', 'Appetitive Behavior', 'Environment, Controlled', 'Grooming', 'Hair', 'Macaca mulatta', 'Motor Activity', 'Observation', 'Self-Injurious Behavior', 'Stereotyped Behavior'] | 18,828,148 | [['B01.050'], ['B01.050.050.199'], ['F01.145.113.111'], ['N06.230.150'], ['F01.145.113.111.453'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['F01.145.632', 'G11.427.410.698'], ['E05.581.249'], ['F01.145.126.980'], ['F01.145.896']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Demonstration of starter unit interprotein transfer from a fatty acid synthase to a multidomain, nonreducing polyketide synthase. | The pathway for substrate transacylation between a fungal type I fatty acid synthase (FAS) and a nonreducing polyketide synthase (NR-PKS) was determined by in vitro reconstitution of dissected domains. System kinetics were influenced by domain dissections, and the FAS phosphopantetheinyl transferase (PPT) monodomain ex... | ['Acyl Carrier Protein', 'Acylation', 'Bacterial Proteins', 'Coenzyme A', 'Fatty Acid Synthases', 'Fatty Acids', 'Polyketide Synthases', 'Protein Interaction Maps', 'Protein Structure, Tertiary', 'Saccharomyces cerevisiae', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Transferases (Other Substitu... | 22,807,303 | [['D12.776.157.050'], ['G02.111.012', 'G02.607.063', 'G03.040'], ['D12.776.097'], ['D03.633.100.759.646.138.382', 'D08.211.211', 'D13.695.667.138.382', 'D13.695.827.068.382'], ['D08.811.277.352.897.387', 'D08.811.520.241.300.287', 'D08.811.682.047.820.196.500', 'D08.811.913.050.134.029.500', 'D08.811.913.050.170.500'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Utilizing multiple scale models to improve predictions of extra-axial hemorrhage in the immature piglet. | Traumatic brain injury (TBI) is a leading cause of death and disability in the USA. To help understand and better predict TBI, researchers have developed complex finite element (FE) models of the head which incorporate many biological structures such as scalp, skull, meninges, brain (with gray/white matter differentiat... | ['Animals', 'Arachnoid', 'Cerebral Hemorrhage', 'Elastic Modulus', 'Finite Element Analysis', 'Models, Biological', 'Pia Mater', 'ROC Curve', 'Stress, Mechanical', 'Sus scrofa', 'Tensile Strength', 'Tomography, Optical Coherence'] | 26,586,144 | [['B01.050'], ['A08.186.566.166'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['G01.374.590.605'], ['E05.355'], ['E05.599.395'], ['A08.186.566.731'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['G01.374.835'], ['B01.050.150.900.6... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Beyond gender: the basis of sexual attraction in bisexual men and women. | The construct of sexual orientation has typically considered the gender of the sexual partner as defining whether the individual is homosexual, bisexual, or heterosexual, and the Kinsey scale conceptualises bisexuality as a point midway between homosexuality and heterosexuality. We propose an alternative model which pl... | ['Adult', 'Aged', 'Bisexuality', 'Female', 'Humans', 'Male', 'Middle Aged', 'Perception', 'Sex Factors', 'Sexual Partners'] | 1,480,717 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.802.975.200', 'G08.686.867.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593'], ['N05.715.350.675', 'N06.850.490.875'], ['M01.778']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Suicide risk and absconding in psychiatric hospitals with and without open door policies: a 15 year, observational study. | BACKGROUND: Inpatient suicide and absconding of inpatients at risk of self-endangering behaviour are important challenges for all medical disciplines, particularly psychiatry. Patients at risk are often admitted to locked wards in psychiatric hospitals to prevent absconding, suicide attempts, and death by suicide. Howe... | ['Adult', 'Female', 'Germany', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Organizational Policy', 'Risk', 'Security Measures', 'Suicide', 'Treatment Outcome'] | 27,477,886 | [['M01.060.116'], ['Z01.542.315'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['I01.655.500.550', 'I01.880.604.825.550', 'N03.623.500.550'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['N04.452.910'], ['F01.1... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Marfan syndrome with myocarditis demonstrated by 99Tcm-HMPAO-labelled WBC and 201Tl scintigraphy: report of three cases in a Chinese family. | Marfan syndrome is a heritable disorder of connective tissue in which the most prominent abnormalities occur in the ocular, cardiovascular and skeletal systems. Although cardiovascular complications are infrequent in patients under 20 years of age, whenever they do occur, they are the major cause of death. Here we repo... | ['Female', 'Humans', 'Leukocytes', 'Male', 'Marfan Syndrome', 'Myocarditis', 'Organotechnetium Compounds', 'Oximes', 'Pedigree', 'Taiwan', 'Technetium Tc 99m Exametazime', 'Thallium Radioisotopes', 'Tomography, Emission-Computed, Single-Photon'] | 8,371,898 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['C05.116.099.674', 'C14.240.400.725', 'C14.280.400.725', 'C16.131.077.550', 'C16.131.240.400.720', 'C16.320.540', 'C17.300.500'], ['C14.280.238.625'], ['D02.691.825'], ['D02.092.570.665'], ['E05.393.673'], ['Z01.252.47... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Pituitary adenylate cyclase-activating polypeptide type 1 (PAC1) receptor is expressed during embryonic development of the earthworm. | Pituitary adenylate cyclase activating polypeptide (PACAP)-like molecules have been shown to be present in cocoon albumin and in Eisenia fetida embryos at an early developmental stage (E1) by immunocytochemistry and radioimmunoassay. Here, we focus on detecting the stage at which PAC1 receptor (PAC1R)-like immunoreacti... | ['Animals', 'Blotting, Western', 'Brain', 'Embryonic Development', 'Ganglia', 'Gene Expression Regulation, Developmental', 'Mice', 'Mice, Inbred BALB C', 'Oligochaeta', 'Organ Specificity', 'Pituitary Gland', 'Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I', 'Tissue Extracts'] | 20,066,549 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['A08.340'], ['G05.308.310'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative evaluation of treated bovine pericardium as a xenograft for hernia repair. | Two forms of bovine pericardium (BPC) were assessed as hernia repair materials: non-cross-linked (lyophilized) and cross-linked through treatment with glutaraldehyde (GA). These were compared with polypropylene mesh (Marlex) in a rabbit model. Over 52 wk implantation, the GA BPC grafts developed a strong, stable, fibro... | ['Animals', 'Biocompatible Materials', 'Cattle', 'Graft Survival', 'Hernia, Ventral', 'Pericardium', 'Polyethylenes', 'Polypropylenes', 'Rabbits', 'Stress, Mechanical', 'Surgical Mesh', 'Transplantation, Heterologous'] | 1,764,549 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['B01.050.150.900.649.313.500.380.271'], ['G12.875.545.340'], ['C23.300.707.374.937'], ['A07.541.795', 'A10.615.789.470'], ['D02.455.326.271.665.550', 'D05.750.716.507', 'D25.720.716.507', 'J01.637.051.720.716.507'], ['D02.455.326.271.665.590', 'D05.750.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Prognostic significance of the activity of nucleolar organizer regions in megakaryocytes from patients with acute lymphoblastic leukemia]. | Bone marrow films from 20 patients with acute lymphoblastic leukemia (ALL) and 40 patients with acute nonlymphoblastic leukemia (ANLL) were investigated using Ag-NOR staining. The control group comprised 12 donors. The activity of nucleolar organizer regions (NOR) in the whole population of megakaryocytes (MK) and in g... | ['Case-Control Studies', 'Humans', 'Leukemia, Myeloid, Acute', 'Megakaryocytes', 'Nucleolus Organizer Region', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Prognosis'] | 8,641,574 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['A11.148.479', 'A15.378.316.479'], ['A11.284.430.106.279.345.190.160.650', 'G05.360.160.650', 'G05.360.340.024.380.875'], ['C04.557.337.428.600', 'C15.604.515.560.60... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An enzymatic method for preparation of homopolymannuronate blocks and strictly alternating sequences of mannuronic and guluronic units. | Two Pseudomonas aeruginosa alginates were lysed by an overexpressed polymannuronate lyase AlxMB (only acting on two or more consecutive, nonacetylated mannuronate units) to prepare either mannuronate blocks (poly-M blocks) with dp approximately 30, or strictly alternating sequences of mannuronic and guluronic acid (pol... | ['Alginates', 'Glucuronic Acid', 'Hexuronic Acids', 'Nuclear Magnetic Resonance, Biomolecular', 'Polysaccharide-Lyases', 'Pseudomonas aeruginosa'] | 9,711,832 | [['D09.698.068'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D02.241.081.844.915.400', 'D02.241.152.811.400', 'D02.241.511.902.915.400', 'D09.811.922.400'], ['E05.196.867.519.550'], ['D08.811.520.241.700'], ['B03.440.400.425.625.625.100', 'B03.660... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Network physiology in insomnia patients: Assessment of relevant changes in network topology with interpretable machine learning models. | Network physiology describes the human body as a complex network of interacting organ systems. It has been applied successfully to determine topological changes in different sleep stages. However, the number of network links can quickly grow above the number of parameters that are typically analyzed with standard stati... | ['Adult', 'Age Distribution', 'Decision Trees', 'Female', 'Humans', 'Machine Learning', 'Male', 'Middle Aged', 'Models, Theoretical', 'Neural Networks, Computer', 'Sleep Initiation and Maintenance Disorders', 'Time Factors', 'Young Adult'] | 31,893,662 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['G17.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['M01.060.116.630'], ['E05.599'], ['G17.485', 'L01.224.050.375.605'], ['C10.886.425.800.800', 'F03.870.400.800.800'], ['G01.910.857'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Pulsatile administration of gonadotropin-releasing hormone does not alter the follicle-stimulating hormone (FSH) isoform distribution pattern of pituitary or circulating FSH in nutritionally growth-restricted ovariectomized lambs. | The experimental induction of puberty by GnRH administration to prepubertal lambs increases serum bioactive FSH (B-FSH) as measured in the rat Sertoli cell aromatase induction bioassay. Serum immunoreactive FSH (I-FSH) levels are unchanged. The increase in serum B-FSH is associated with an increase in the proportion of... | ['Animal Nutritional Physiological Phenomena', 'Animals', 'Female', 'Follicle Stimulating Hormone', 'Gonadotropin-Releasing Hormone', 'Growth Disorders', 'Isoenzymes', 'Luteinizing Hormone', 'Ovariectomy', 'Pituitary Gland', 'Pulsatile Flow', 'Sheep', 'Tissue Distribution'] | 8,462,450 | [['G07.203.650.161'], ['B01.050'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['C23.550.393'], ['D08.811.348', 'D12.776.800.300'], ['D06.47... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of Ca2+ on the promiscuous target-protein binding of calmodulin. | Calmodulin (CaM) is a calcium sensing protein that regulates the function of a large number of proteins, thus playing a crucial part in many cell signaling pathways. CaM has the ability to bind more than 300 different target peptides in a Ca2+-dependent manner, mainly through the exposure of hydrophobic residues. How C... | ['Animals', 'Apoproteins', 'Binding Sites', 'Calcium', 'Calcium Signaling', 'Calmodulin', 'Computational Biology', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Molecular Dynamics Simulation', 'Protein Binding', 'Protein Conformation', 'Static Electricity'] | 29,614,072 | [['B01.050'], ['D12.776.070'], ['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['H01.158.273.180', 'L01.313.124'], ['B01.050.150.900.649.313.988.400.112.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Who Are the "Lazy" Ants? The Function of Inactivity in Social Insects and a Possible Role of Constraint: Inactive Ants Are Corpulent and May Be Young and/or Selfish. | Social insect colonies are commonly thought of as highly organized and efficient complex systems, yet high levels of worker inactivity are common. Although consistently inactive workers have been documented across many species, very little is known about the potential function or costs associated with this behavior. He... | ['Animals', 'Ants', 'Behavior, Animal', 'Biological Evolution', 'Body Size', 'Social Behavior'] | 28,957,517 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['F01.145.113'], ['G05.045', 'G16.075'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['F01.145.813']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The calcium-sensing receptor regulates plasma membrane calcium adenosine triphosphatase isoform 2 activity in mammary epithelial cells: a mechanism for calcium-regulated calcium transport into milk. | The calcium-sensing receptor (CaR) regulates transepithelial calcium transport into milk by mammary epithelial cells. Using a genome-wide screening strategy, we identified the plasma membrane calcium ATPase isoform 2 (PMCA2) as a potential downstream target of the CaR. We show that PMCA2 expression in the mouse mammary... | ['Animals', 'Biological Transport', 'Blotting, Western', 'Calcium', 'Cells, Cultured', 'Epithelial Cells', 'Female', 'Fluorescent Antibody Technique', 'Gadolinium', 'Isoenzymes', 'Lactation', 'Mammary Glands, Animal', 'Mice', 'Mice, Inbred BALB C', 'Microscopy, Immunoelectron', 'Milk', 'Milk Proteins', 'Mutation', 'Oli... | 17,823,248 | [['B01.050'], ['G03.143'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['A11.436'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Exoskeleton Morphology of Three Species of Preponini, with Discussion of Morphological Similarities among Neotropical Charaxinae (Lepidoptera: Nymphalidae)-II. Thorax and Thoracic Appendages. | The present report, the second part of a study of the external morphology of Preponini, compares the thorax and thoracic appendages of Archaeoprepona demophon demophon (Linnaeus, 1758), Archaeoprepona licomedes licomedes (Cramer, 1777) and Prepona pylene pylene Hewitson, [1854], through descriptions and illustrations. ... | ['Animals', 'Butterflies', 'Extremities', 'Species Specificity', 'Thorax', 'Wings, Animal'] | 26,003,985 | [['B01.050'], ['B01.050.500.131.617.720.500.500.937.200'], ['A01.378'], ['G16.824'], ['A01.923.761'], ['A13.395.823']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Drop-out and treatment outcome of outpatient cognitive-behavioral therapy for anorexia nervosa and bulimia nervosa. | In the present study, drop-out-analyses were carried out for a manual-based cognitive-behavioral therapy for 104 females with anorexia nervosa (AN) and bulimia nervosa (BN), in the service setting of a university outpatient clinic (naturalistic setting). A total of 22.9% of patients with AN terminated therapy premature... | ['Adult', 'Anorexia Nervosa', 'Bulimia Nervosa', 'Cognitive Behavioral Therapy', 'Female', 'Humans', 'Outpatients', 'Patient Dropouts', 'Personality Disorders', 'Treatment Outcome'] | 23,587,528 | [['M01.060.116'], ['F03.400.125'], ['F03.400.250'], ['F04.754.137.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.630'], ['F01.100.150.750.500.610', 'F01.145.488.887.500.610', 'N05.300.150.800.500.610'], ['F03.675'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Determinism and probability in the development of the cell theory. | A return to Claude Bernard's original use of the concept of 'determinism' displays the fact that natural laws were presumed to rule over all natural processes. In a more restricted sense, the term boiled down to a mere presupposition of constant determinant causes for those processes, leaving aside any particular ontol... | ['Cell Biology', 'Cells', 'Genetics', 'History, 19th Century', 'History, 20th Century', 'Probability'] | 22,542,690 | [['H01.158.100.433', 'H01.158.273.160'], ['A11'], ['H01.158.273.343'], ['K01.400.504.937'], ['K01.400.504.968'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600']] | ['Disciplines and Occupations [H]', 'Anatomy [A]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Nancy Main Henley (1934-2016). | Presents an obituary for Nancy Main Henley who passed away on June 4, 2016, in Maryland. Henley was a feminist trailblazer who conducted influential work on gender, communication, and power. (PsycINFO Database Record | ['Feminism', 'History, 20th Century', 'Humans', 'Psychology', 'United States'] | 28,032,795 | [['I01.880.604.473.374', 'K01.752.566.479.174.700'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.096.628'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Stability of minute virus of mice to chemical and physical agents. | Minute virus of mice (MVM), a single-stranded deoxyribonucleic acid Parvovirus, was subjected to various inactivation procedures, including chemical disinfectants, heat, and ultraviolet radiation. MVM was found to be less stable than has been reported for other Parvoviruses. This virus was readily inactivated by a vari... | ['1-Propanol', 'Animals', 'Cell Line', 'Chloroform', 'Cytopathogenic Effect, Viral', 'Disinfectants', 'Ethanol', 'Formaldehyde', 'Glutaral', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Mice', 'Parvoviridae', 'Propanols', 'Radiation Effects', 'Rats', 'Sodium Hypochlorite', 'Ultraviolet Rays'] | 4,213,983 | [['D02.033.755.600'], ['B01.050'], ['A11.251.210'], ['D02.455.526.439.224', 'D02.455.526.913.810'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['D27.505.954.122.425', 'D27.720.274'], ['D02.033.375'], ['D02.047.407'], ['D02.047.532'], ['G01.906.595.543', 'G16.500.275.063.725.71... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cyclic adenosine 3', 5' monophosphate: a possible indicator of premalignant changes in the large bowel. | Cyclic adenosine 3', 5' monophosphate (cyclic-AMP) has been estimated in mucosal biopsy samples removed from the descending colon and rectum at endoscopy to investigate the possibility of using this substance for monitoring pre-malignant changes in the large bowel. Four groups of patients have been studied: those with ... | ['Colonic Neoplasms', 'Cyclic AMP', 'Humans', 'Intestinal Mucosa', 'Intestinal Neoplasms', 'Intestine, Large', 'Precancerous Conditions', 'Rectal Neoplasms'] | 229,758 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Entry kinetics and cell-cell transmission of surface-bound retroviral vector particles. | BACKGROUND: Transduction with recombinant HIV-1 derived lentivirus vectors is a multi-step process initiated by surface attachment and subsequent receptor-directed uptake into the target cell. We previously reported the retention of vesicular stomatitis virus G protein pseudotyped particles on murine progenitor cells a... | ['Animals', 'Bone Marrow Cells', 'Cell Communication', 'Cell Line', 'Cell Lineage', 'Cell Membrane', 'Extracellular Matrix', 'Fibronectins', 'Genetic Vectors', 'Green Fluorescent Proteins', 'Heparin', 'Humans', 'Kinetics', 'Mice', 'Peptide Hydrolases', 'Proviruses', 'Retroviridae', 'Time Factors', 'Transduction, Geneti... | 20,440,757 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.085'], ['A11.251.210'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A11.284.149'], ['A11.284.295.310'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['G05.360.337'], ['D12.776.532.265... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk factors for Pneumocystis jirovecii pneumonia in patients with lymphoproliferative disorders. | BACKGROUND: Guidelines for primary Pneumocystis jirovecii pneumonia (PCP) prophylaxis for patients with hematologic malignancy (HM) are still lacking. Our objective was to identify risk factors for PCP among patients with HM to help recognize patients who would benefit from primary PCP prophylaxis.MATERIAL AND METHODS:... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Case-Control Studies', 'Cladribine', 'Female', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymphoma, Non-Hodgkin', 'Lymphoproliferative Disorders', 'Male', 'Middle Aged', 'Pneumocystis carinii', 'Pneumonia, Pneumocystis', 'Retrospective Studies', 'Risk Fa... | 22,000,698 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D03.633.100.759.590.138.300.200', 'D03.633.100.759.590.138.325.075', 'D13.570.230.229.075', 'D13.570.583.138.300.200', 'D13.570.583.138.325.075', 'D13.570.800.096.300.200'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy and Safety of Budesonide, vs Mesalazine or Placebo, as Induction Therapy for Lymphocytic Colitis. | BACKGROUND & AIMS: Lymphocytic colitis is a common cause of chronic, nonbloody diarrhea. However, the effects of treatment are unclear and randomized placebo-controlled trials were requested in a Cochrane review. We performed a randomized, placebo-controlled, multicenter study to evaluate budesonide and mesalazine as i... | ['Administration, Oral', 'Anti-Inflammatory Agents', 'Budesonide', 'Colitis, Lymphocytic', 'Double-Blind Method', 'Drug Administration Schedule', 'Female', 'Humans', 'Induction Chemotherapy', 'Male', 'Mesalamine', 'Middle Aged', 'Treatment Outcome'] | 30,195,447 | [['E02.319.267.100'], ['D27.505.954.158'], ['D04.210.500.745.745.654.105'], ['C06.405.205.265.173.750', 'C06.405.469.158.188.173.750'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.499', 'E02.860.500'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluating photographic scales of facial pores and diagnostic agreement of tests using latent class models. | BACKGROUND: Ordinal severity scales illustrated by photographs have been widely developed to help dermatologists in evaluating skin problems or improvements. Numerous scales have been published, and none of them were used for assessing facial pores.METHODS: A five-point photographic scale of facial pores was formulated... | ['Adult', 'Female', 'Humans', 'Models, Statistical', 'Nose', 'Observer Variation', 'Photography', 'Probability', 'Reproducibility of Results', 'Skin', 'Skin Aging'] | 27,775,445 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['A01.456.505.733', 'A04.531', 'A09.531'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E01.370.350.600', 'E05.712'], ['E05.318.740.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association of the HOPA12bp allele with a large X-chromosome haplotype and positive symptom schizophrenia. | HOPA is a X-chromosome gene that encodes an essential nuclear receptor co-activator. Previously, we have demonstrated that an exonic polymorphism, termed HOPA(12bp), in the Opa (Opposite Paired) domain of this gene that is critical for neuronal growth and differentiation is associated with a low risk for schizophrenia.... | ['Adolescent', 'Adult', 'Alleles', 'Chromosomes, Human, X', 'Cluster Analysis', 'Exons', 'Female', 'Genotype', 'Haplotypes', 'Humans', 'Male', 'Mediator Complex', 'Phenotype', 'Polymorphism, Genetic', 'Receptors, Thyroid Hormone', 'Schizophrenia'] | 15,108,174 | [['M01.060.057'], ['M01.060.116'], ['G05.360.340.024.340.030'], ['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G05.360.340.024.340.137.232'], ['G05.380'], ['G05.380.360'], ['B01.05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Areas of the brain concerned with ventilatory load compensation in awake man. | There is broad agreement that the awake human ventilatory response to a moderate inspiratory load consists of a prolongation of inspiratory time (T(I)) with a maintenance of tidal volume (V(T)) and end-tidal P(C)(O(2)) (P(ET,C)(O(2))), the response being severely blunted in sleep. There is no agreement on the mechanism... | ['Adaptation, Physiological', 'Adult', 'Brain', 'Brain Mapping', 'Cerebrovascular Circulation', 'Humans', 'Inhalation', 'Male', 'Supine Position', 'Tidal Volume', 'Time Factors', 'Tomography, Emission-Computed', 'Work of Breathing'] | 11,897,862 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.772.705.700.390'], ['G11.427.695.625'], ['E01.370.386.700.485.750.900.350.750', 'G09.772.850.970.500.700']... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Madin-Darby canine kidney cells. I. Aldosterone-induced domes and their evaluation as a model system. | Vectorial transport of salt and water in the Madin-Darby canine kidney (MDCK) cell line is indicated by the formation of domes when a monolayer is grown on an impermeable support. We investigated aldosterone-induced dome formation and evaluated the dome as an experimental model. Transepithelial dome resistance was abou... | ['Aldosterone', 'Alprostadil', 'Animals', 'Biological Transport, Active', 'Blood', 'Cell Line', 'Chlorides', 'Dogs', 'Electric Conductivity', 'Epithelium', 'Kidney', 'Membrane Potentials', 'Models, Biological', 'Potassium', 'Sodium', 'Transferrin'] | 2,235,294 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['G03.143.310'], ['A12.207.152', 'A15.145'], ['A11.251.210'], ['D01.210.450.150', 'D01.248.497.158.215'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.35... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrophysiological mechanisms of spontaneous termination of sustained monomorphic reentrant ventricular tachycardia in the canine postinfarction heart. | BACKGROUND: The electrophysiological mechanisms of spontaneous termination of sustained monomorphic ventricular tachycardia (SMVT), in the postinfarction heart, generally considered secondary to a reentrant mechanism, have not been fully investigated.METHODS AND RESULTS: Epicardial activation maps of spontaneous termin... | ['Animals', 'Dogs', 'Electrophysiology', 'Heart', 'Heart Conduction System', 'Male', 'Myocardial Infarction', 'Tachycardia, Ventricular'] | 8,608,626 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['H01.158.344.528', 'H01.158.782.236'], ['A07.541'], ['A07.541.409'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['C14.280.067.845.940', 'C14.280.123.875.940', 'C23.550.073.845.940']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of low molecular weight heparins for the prevention of postoperative venous thromboembolism in general surgery. A survey of practice in the United States. | BACKGROUND: Even though low molecular weight heparins (LMWHs) have become the standard for venous thromboembolism (VTE) prophylaxis in most European countries and Canada, it was not until recently that LMWHs were approved for use in the United States. The main objective of this study was to assess the current preferenc... | ['Anticoagulants', 'Attitude of Health Personnel', 'Bandages', 'Cost-Benefit Analysis', 'General Surgery', 'Health Care Surveys', 'Heparin, Low-Molecular-Weight', 'Humans', 'Incidence', 'Postoperative Complications', 'Practice Guidelines as Topic', 'Risk Factors', 'Severity of Illness Index', 'Surveys and Questionnaire... | 11,941,278 | [['D27.505.954.502.119'], ['F01.100.050', 'N05.300.100'], ['E07.101'], ['N03.219.151.125'], ['H02.403.810.300'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['D09.698.373.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.52... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Serum prealbumin and retinol-binding protein in the prealbumin-related senile and familial forms of systemic amyloidosis. | In a series of 13 elderly patients with proven prealbumin-related senile systemic amyloidosis (SSA), depressed serum prealbumin values (110.7 +/- 14.1 micrograms/ml) were found as compared to an age-matched control group (175.1 +/- 20.3 micrograms/ml). As expected, there was a significant correlation between serum prea... | ['Adult', 'Aged', 'Amyloidosis', 'Female', 'Haptoglobins', 'Heart Diseases', 'Humans', 'Lung Diseases', 'Male', 'Middle Aged', 'Prealbumin', 'Retinol-Binding Proteins', 'Serum Amyloid A Protein'] | 4,038,761 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.845.500'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['M01.060.116.630'], ['D12.776.034.841.450', 'D12.776.124.727.750'], ['D12.776.157.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Blood pressure reduction in stable angina by nifedipine was related to stroke and heart failure reduction but not to coronary interventions. | BACKGROUND AND OBJECTIVE: Whether blood pressure (BP) reduction is a necessary prerequisite for cardiovascular risk reduction or an epiphenomenon has not been definitively established. We used an innovative analytic method to address this question.METHODS: For 7,287 participants in a stable angina trial comparing long-... | ['Angina Pectoris', 'Blood Pressure', 'Calcium Channel Blockers', 'Cardiac Output, Low', 'Clinical Trials as Topic', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nifedipine', 'Stroke', 'Treatment Outcome'] | 17,573,988 | [['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['C14.280.148', 'C23.888.192'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E01.370.350.130.625', 'E... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Brief, Non-Pharmacological, Interventions for Pediatric Anxiety: Meta-Analysis and Evidence Base Status. | In 1998, Ost published [One-session treatment of specific phobias-a rapid and effective method] [in Swedish] giving rise to the idea that brief, intensive, and concentrated psychosocial interventions could exhibit public health impact. At this juncture, and per criteria of the Society for Clinical Child and Adolescent ... | ['Adolescent', 'Anxiety', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male'] | 32,285,692 | [['M01.060.057'], ['F01.470.132'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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