Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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TEs or not TEs? That is the evolutionary question. | Transposable elements (TEs) have contributed a wide range of functional sequences to their host genomes. A recent paper in BMC Molecular Biology discusses the creation of new transcripts by transposable element insertion upstream of retrocopies and the involvement of such insertions in tissue-specific post-transcriptio... | ['Animals', 'Base Sequence', 'Conserved Sequence', 'DNA Transposable Elements', 'Databases, Genetic', 'Drosophila melanogaster', 'Evolution, Molecular', 'Gene Deletion', 'Gene Dosage', 'Gene Duplication', 'Gene Expression Regulation', 'Genes, Plant', 'Genetic Speciation', 'Genome', 'Genome, Human', 'Humans', 'Models, G... | 19,863,763 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Does sedentary behavior increase the risk of low back pain? A population-based co-twin study of Spanish twins. | BACKGROUND: The relationship between sedentary lifestyle and low back pain (LBP) remains unclear and previous research has not accounted for genetic and early environmental factors.PURPOSE: Our aim was to investigate if sedentary behavior is associated with the lifetime prevalence of persistent LBP and the risk of deve... | ['Case-Control Studies', 'Female', 'Gene-Environment Interaction', 'Humans', 'Low Back Pain', 'Male', 'Middle Aged', 'Sedentary Behavior', 'Spain', 'Twins'] | 28,232,052 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.695.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['M01.060.116.630'], ['F01.145.749', 'F01.829.458.705'], ['Z01.542.846'], ['M01.438.873']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reasons for readmission after carotid endarterectomy. | OBJECTIVE: With increasing oversight of postoperative outcomes with the Patient Protection and Affordable Care Act, the reduction of readmissions is necessary to avoid financial penalties. This article provides a multi-institutional, multivariate analysis of the pre- and postoperative patient factors associated with re... | ['Aged', 'Benchmarking', 'Comorbidity', 'Endarterectomy, Carotid', 'Female', 'Humans', 'Male', 'Patient Readmission', 'Postoperative Complications', 'Quality Improvement', 'Risk Adjustment', 'Risk Factors', 'Treatment Outcome'] | 23,973,514 | [['M01.060.116.100'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['N05.715.350.225', 'N06.850.490.687'], ['E04.100.814.456.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.620', 'N02.421.585.400.620'], ['C23.550.767'], ['J01.293.754', 'N04.761.7... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Impact of routine percutaneous coronary intervention after out-of-hospital cardiac arrest due to ventricular fibrillation. | INTRODUCTION: Since 2003, we have routinely used percutaneous coronary intervention (PCI) and mild therapeutic hypothermia (MTH) to treat patients < 80 years of age after out-of-hospital cardiac arrest (OHCA) related to ventricular fibrillation. The aim of our study was to evaluate the prognostic impact of routine PCI ... | ['Adult', 'Age Factors', 'Aged', 'Cardiopulmonary Resuscitation', 'Coronary Angiography', 'Female', 'Humans', 'Hypothermia, Induced', 'Male', 'Middle Aged', 'Out-of-Hospital Cardiac Arrest', 'Prognosis', 'Treatment Outcome', 'Ventricular Fibrillation'] | 21,569,361 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E02.365.647.110'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['M01.060.116.630'], ['C14.280.383.610'], ['E01.789'], [... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A naturally occurring substitution in human immunodeficiency virus Tat increases expression of the viral genome. | A natural amino acid substitution in the human immunodeficiency virus type 1 (HIV-1) transcriptional activator Tat increases its activity and compensates for deleterious mutations elsewhere in the Tat protein. Substitution of asparagine for threonine 23 increases Tat transactivation of the HIV-1 promoter and the bindin... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Asparagine', 'Gene Products, tat', 'Genetic Variation', 'Genome, Viral', 'HIV-1', 'Humans', 'Leukocytes, Mononuclear', 'Molecular Sequence Data', 'Positive Transcriptional Elongation Factor B', 'Protein-Serine-Threonine Kinases', 'Transcription, Genetic', 'Transcripti... | 12,857,933 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['D12.776.260.755.199', 'D12.776.930.900.199', 'D12.776.964.900.750.750', 'D12.776.964.925.984.400'], ['G05.365'], ['G05.360.340.358.840'], ['B04.820.650.589.650.350.400'], ['B... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessment of cadmium content of potato grown in Weining County, Guizhou Province, China. | A total of 54 soil and 54 potato samples have been collected from Weining County to evaluate the accumulation of cadmium in potatoes. The concentrations of the total Cd and the available Cd in the soil samples have been detected. The total concentrations of Cd were from 0.41 to 10.0 mg/kg with an average value of 2.60 ... | ['Cadmium', 'China', 'Environmental Monitoring', 'Models, Theoretical', 'Soil', 'Soil Pollutants', 'Solanum tuberosum'] | 28,432,509 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.599'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756'], ['B01.650.940.800.575.912.250.908.500.725.777']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Evaluation of Optical Coherence Tomography Meibography in Patients With Obstructive Meibomian Gland Dysfunction. | PURPOSE: To evaluate optical coherence tomography meibography (OCT-M) in patients with and without obstructive meibomian gland dysfunction (MGD) and to determine the relationship between OCT-M and ocular surface clinical tests.METHODS: Twenty-two patients with MGD and 16 control subjects were included. Each patient und... | ['Adult', 'Diagnostic Techniques, Ophthalmological', 'Eyelid Diseases', 'Female', 'Humans', 'Male', 'Meibomian Glands', 'Middle Aged', 'Observer Variation', 'Tears', 'Tomography, Optical', 'Tomography, Optical Coherence', 'Young Adult'] | 26,226,467 | [['M01.060.116'], ['E01.370.380'], ['C11.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.337.614', 'A10.336.827.600'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['A12.200.882'], ['E01.370.350.589.249', 'E01.370.350.825.805', 'E05.642.249'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytochrome c is dispensable for fas-induced caspase activation and apoptosis. | Cytochrome c is thought to play an important role in the initiation of apoptosis following its release from mitochondria. It is controversial whether such release is also involved in caspase activation and apoptotic cell death after ligation of the cell surface molecule Fas. We addressed this issue by investigating cel... | ['Adenosine Triphosphate', 'Apoptosis', 'Caspases', 'Coumarins', 'Cytochrome c Group', 'Dose-Response Relationship, Drug', 'Electroporation', 'Enzyme Activation', 'Humans', 'Jurkat Cells', 'Oligomycins', 'Oligopeptides', 'Proton-Translocating ATPases', 'Signal Transduction', 'Staurosporine', 'Tumor Cells, Cultured', 'f... | 10,405,325 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D08.244.286', 'D12.776.422.220.286'], ['G07.690.773.875', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pediatric lung transplantation for cystic fibrosis. | Pediatric lung transplantation for cystic fibrosis has uncertain survival effects. Three retrospective studies disagree on survival benefit. The US Lung Allocation Score has changed patient selection for lung transplantation but confounds the analysis of survival outcomes. A prospective trial is needed to resolve clini... | ['Child', 'Cystic Fibrosis', 'Graft Survival', 'Humans', 'Lung Transplantation', 'Patient Selection', 'Treatment Outcome'] | 18,791,441 | [['M01.060.406'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.928.600.495', 'E04.936.450.495'], ['E05.581.500.653', 'N04.590.731'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Monte Carlo calculation of the wall correction factors for ionization chambers and Aeq for 60Co gamma rays. | The application of cavity-ionization chambers to the standadization of 60Co gamma-ray beams, in terms of exposure, requires that the specific ionization of air Jg, be corrected for the attenuation and scatter of the incident rays by the wall, central electrode, and supporting stem of the chamber. A Monte Carlo photon-e... | ['Cobalt Radioisotopes', 'Electron Transport', 'Gamma Rays', 'Monte Carlo Method', 'Nuclear Reactors', 'Operations Research', 'Radionuclide Generators', 'Scattering, Radiation'] | 713,976 | [['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Lower Magnetization Transfer Ratio in the Forceps Minor Is Associated with Poorer Gait Velocity in Older Adults. | BACKGROUND AND PURPOSE: Gait disturbances in the elderly are disabling and a major public health issue but are poorly understood. In this multimodal MR imaging study, we used 2 voxel-based analysis methods to assess the voxelwise relationship of magnetization transfer ratio and white matter hyperintensity location with... | ['Adult', 'Aged', 'Brain', 'Female', 'Gait', 'Gait Disorders, Neurologic', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged'] | 27,979,793 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C10.597.404', 'C23.888.592.413'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunogenicity and Safety of an EB66 Cell-Culture-Derived Influenza A/Indonesia/5/2005(H5N1) AS03-Adjuvanted Vaccine: A Phase 1 Randomized Trial. | BACKGROUND: Cell-culture-derived (CC) influenza vaccine production methods could provide benefits over classical embryonated-egg technology, including a higher production capacity and the faster creation of a supply that meets demand.METHODS: A CC-inactivated split-virus influenza A/Indonesia/5/2005(H5N1) vaccine deriv... | ['Adjuvants, Immunologic', 'Adolescent', 'Adult', 'Animals', 'Antibodies, Viral', 'Cell Line', 'Drug Combinations', 'Ducks', 'Embryonic Stem Cells', 'Female', 'Humans', 'Influenza A Virus, H5N1 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Middle Aged', 'Polysorbates', 'Single-Blind Method', 'Squalene', ... | 25,722,291 | [['D27.505.696.477.067'], ['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.251.210'], ['D26.310'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['A11.872.700.250'], ['B01.050.150.900.649.313.988.400.112... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Phenotypical characteristics of group B streptococcus in parturients. | Colonization by Group B Streptococcus (GBS) is highly prevalent among pregnant women, with prevalence rates ranging between 4% and 30%. The infection may be transmitted vertically and may result in serious neonatal consequences. In the period from November 2003 to May 2004, a cross-sectional study was carried out among... | ['Adult', 'Anti-Bacterial Agents', 'Carrier State', 'Cross-Sectional Studies', 'Female', 'Humans', 'Microbial Sensitivity Tests', 'Phenotype', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Rectum', 'Risk Factors', 'Serotyping', 'Streptococcal Infections', 'Streptococcus agalactiae', 'Vagina'] | 17,625,774 | [['M01.060.116'], ['D27.505.954.122.085'], ['N06.850.520.169'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G05.695'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['A... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Decisional capacity of depressed elderly to consent to electroconvulsive therapy. | The purpose of this article is to determine the abilities of severely depressed elderly to consent to electroconvulsive therapy (ECT) and to investigate the impact of educational intervention on their capacity. Forty severely depressed adults referred for ECT, with Mini-Mental State Examination scores greater than 20, ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bipolar Disorder', 'Decision Making', 'Depressive Disorder, Major', 'Electroconvulsive Therapy', 'Female', 'Humans', 'Informed Consent', 'Male', 'Mental Competency', 'Mental Status Schedule', 'Middle Aged', 'Patient Education as Topic', 'Patient Participation', 'Psychiatric Depar... | 15,018,698 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.084.500'], ['F02.463.785.373'], ['F03.600.300.375'], ['F04.570.200.583', 'F04.669.224.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['F01.590', 'F... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases. | Interleukin 5 (IL-5) induces proliferation and differentiation of B cells and eosinophils by interacting with its receptor (IL-5R) which consists of two distinct polypeptide chains, alpha and beta (beta c). Although both IL-5R alpha and beta c lack a kinase catalytic domain, IL-5 is capable of inducing tyrosine phospho... | ['Agammaglobulinaemia Tyrosine Kinase', 'Animals', 'Antibodies, Monoclonal', 'B-Lymphocytes', 'Benzoquinones', 'Cell Line', 'Cricetinae', 'Enzyme Activation', 'Humans', 'Interleukin-5', 'Janus Kinase 1', 'Janus Kinase 2', 'Kinetics', 'Lactams, Macrocyclic', 'Lymphocyte Activation', 'Macromolecular Substances', 'Mice', ... | 7,525,847 | [['D08.811.913.696.620.682.725.025'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D02.806.250'], ['A11.251.210'], ['B01.050.150.900.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
One, two-, and three-level instrumented posterolateral fusion of the lumbar spine with a local bone graft: a prospective study with a 2-year follow-up. | STUDY DESIGN: Prospective trial.OBJECTIVE: To examine the difference in bone union and clinical results after one-, two-, and three-level instrumented posterolateral fusion surgery using a local bone graft.SUMMARY OF BACKGROUND DATA: The iliac crest bone graft technique for lumbar posterolateral fusion surgery is widel... | ['Aged', 'Aged, 80 and over', 'Bone Transplantation', 'Female', 'Follow-Up Studies', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Pain Measurement', 'Prospective Studies', 'Sacrum', 'Spinal Fusion'] | 21,224,776 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A methodological investigation of the Intermodal Preferential Looking paradigm: Methods of analyses, picture selection and data rejection criteria. | The Intermodal Preferential Looking paradigm provides a sensitive measure of a child's online word comprehension. To complement existing recommendations (Fernald, Zangl, Portillo, & Marchman, 2008), the present study evaluates the impact of experimental noise generated by two aspects of the visual stimuli on the robust... | ['Acoustic Stimulation', 'Comprehension', 'Female', 'Fixation, Ocular', 'Humans', 'Infant', 'Infant Behavior', 'Language', 'Male', 'Noise', 'Photic Stimulation', 'Recognition, Psychology', 'Reproducibility of Results', 'Research Design'] | 26,176,183 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['F02.463.188.357'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.145.179.500'], ['F01.145.209.399', 'L01.559'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['E05.723.729'], ['F02.463.425.540.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Elements of resilience after the World Trade Center disaster: reconstituting New York City's Emergency Operations Centre. | In this paper we examine the reconstitution of the Emergency Operations Centre (EOC) after its destruction in the World Trade Center attack, using that event to highlight several features of resilience. The paper summarises basic EOC functions, and then presents conceptions of resilience as understood from several disc... | ['Aircraft', 'Crisis Intervention', 'Disaster Planning', 'Emergency Medical Services', 'Humans', 'Interinstitutional Relations', 'New York City', 'Rescue Work', 'Terrorism'] | 12,703,151 | [['J01.937.285.100'], ['F04.754.252'], ['N06.230.100.035'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.822.400'], ['Z01.107.567.875.350.530.530', 'Z01.107.567.875.500.530.530', 'Z01.433.741'], ['N06.230.100.350'], ['I01.198.240.856.800', 'I01.880.735.900.800']] | ['Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Phase II and pharmacodynamic studies of pyrazine diazohydroxide (NSC 361456) in patients with advanced renal and colorectal cancer. | Pyrazine diazohydroxide (PZDH) is a novel antitumor agent that forms DNA adducts via the reactive pyrazine diazonium ion. In a recent Phase I study of PZDH, we identified a recommended Phase II dose of 100 mg/m2/day x 5, given as a 5-min i.v. bolus with the cycles repeated every 42 days (N. J. Vogelzang, et al, Cancer ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Cell Count', 'Colorectal Neoplasms', 'Female', 'Humans', 'Kidney Neoplasms', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Pyrazines', 'Survival Rate'] | 9,563,886 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dietary exposure to acrylamide in a group of Japanese adults based on 24-hour duplicate diet samples. | Acrylamide is a probable human carcinogen and known human neurotoxin that can be generated in food through heating. Using a mathematical modelling approach, our previous study estimated long-term average dietary exposure to acrylamide in the Japanese people; however, the validity of these estimates remained unknown. He... | ['Acrylamide', 'Adult', 'Aged', 'Diet', 'Dietary Exposure', 'Female', 'Food Contamination', 'Healthy Volunteers', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Vegetables', 'Young Adult'] | 30,650,020 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['M01.060.116'], ['M01.060.116.100'], ['G07.203.650.240'], ['N06.850.460.350.040'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.59... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[Geosystemic zoning as a basis for rehabilitation environmental measures of mining and smelting complex (exemplified by metallurgic plant)]. | The article covers a method for zoning of natural technogenic geosystem (exemplified by territory of ash-heap from metallurgic enterprise - one of the major metallurgic enterprises in Russia). The method is based on main principles of systemic approach and enables objective evaluation of space-time spread of pollution ... | ['Conservation of Natural Resources', 'Environmental Monitoring', 'Environmental Pollution', 'Metallurgy', 'Mining', 'Russia'] | 30,351,783 | [['J01.256', 'N06.230.080'], ['N06.850.460.350.080', 'N06.850.780.375'], ['N06.850.460'], ['J01.576.655.875.400'], ['J01.576.655.875.500'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Quantitative detection of Helicobacter pylori in water samples by real-time PCR amplification of the cag pathogenicity island gene, cagE. | AIMS: A new real-time PCR assay that simultaneously amplifies a 102-bp fragment of the cagE gene from Helicobacter pylori and a new internal positive control containing a specific sequence of the gyrB gene from Aeromonas hydrophila, was developed and validated for the detection of H. pylori in environmental samples.MET... | ['Bacterial Proteins', 'DNA Primers', 'DNA, Bacterial', 'Helicobacter pylori', 'Limit of Detection', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Waste Disposal, Fluid', 'Water Microbiology', 'Water Supply'] | 19,302,298 | [['D12.776.097'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.212'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.393.620.500'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.70... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Spinal meningeal melanocytoma simulating neurinoma: case report]. | Meningeal melanocytomas are infrequent tumors that when located in the spinal cord and because of their close relationship to the nerve root can resemble a neurinoma. The MRl can help to differentiate them from the neurinomas preoperatively. The case of a female patient harboring a cervical meningeal melanocytoma invol... | ['Adolescent', 'Diagnosis, Differential', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Meningeal Neoplasms', 'Meningioma', 'Neurilemmoma'] | 12,444,412 | [['M01.060.057'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.557.580.520', 'C04.557.645.520', 'C04.588.614.250.580.500', 'C10.551.240.500.500'], ['C04.557.465.625.650.595', 'C04.557.580.600.610.595', 'C04.557.580.625.650.595']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effect of neuroactivating amino acids on the system activating sympathetic preganglionic neurons]. | In anesthetized cats, the bioelectrical responses were recorded in T3 white ramus during stimulation of intercostal nerve of the T3 segment and of descending pathways (dorsolateral funiculus) of the C5 segment. The effects of GABA, glycine (and its synaptic antagonists picrotoxin and strychnine), and of glutamic acid o... | ['Aminobutyrates', 'Animals', 'Autonomic Fibers, Preganglionic', 'Cats', 'Glutamates', 'Glycine', 'Interneurons', 'Muscles', 'Neurons, Afferent', 'Picrotoxin', 'Reaction Time', 'Reflex', 'Spinal Cord', 'Strychnine', 'Sympathetic Nervous System', 'Vasomotor System', 'gamma-Aminobutyric Acid'] | 658,543 | [['D02.241.081.114.500', 'D12.125.190'], ['B01.050'], ['A08.675.127.500.060', 'A08.675.542.234.060', 'A08.800.050.050.060', 'A08.800.800.060.060', 'A11.671.188.500.060', 'A11.671.501.234.060'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.481'], ['A08.675.358', 'A11... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of the Krusen Limb Load Monitor to quantify temporal and loading measurements of gait. | The purposes of this investigation were to determine whether the temporal and force measurements from the Krusen Limb Load Monitor produced clinically reliable data and to begin identifying the factors that determine the monitor's reliability. Temporal and loading measurements were made from the output of the Krusen Li... | ['Biomechanical Phenomena', 'Female', 'Gait', 'Humans', 'Male', 'Physical Therapy Modalities'] | 7,089,061 | [['G01.154.090', 'G01.374.089'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.779', 'E02.831.535']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The regeneration potential after human and autologous stem cell transplantation in a rat sciatic nerve injury model can be monitored by MRI. | Traumatic nerve injuries are a major clinical challenge. Tissue engineering using a combination of nerve conduits and cell-based therapies represents a promising approach to nerve repair. The aim of this study was to examine the regeneration potential of human adipose-derived stem cells (hASCs) after transplantation in... | ['Adipose Tissue', 'Animals', 'Disease Models, Animal', 'Female', 'Fibrin', 'Humans', 'Immunohistochemistry', 'Magnetic Resonance Imaging', 'Nerve Regeneration', 'Peripheral Nerve Injuries', 'Radiography', 'Rats', 'Rats, Sprague-Dawley', 'Schwann Cells', 'Sciatic Nerve', 'Stem Cell Transplantation', 'Stem Cells', 'Tiss... | 24,380,629 | [['A10.165.114'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.124.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.1... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Situational profile and intervention strategy in the Mesoamerican region in maternal, neonatal and reproductive health area]. | To present the main results of the regional situation diagnosis and intervention plan developed in 2010 as part of the planning activities of the Mesoamerican Health System by the Working Group on Maternal, Reproductive and Neonatal Health. A group of experts and representatives from countries in the region (Central Am... | ['Adolescent', 'Adult', 'Central America', 'Child', 'Child Health Services', 'Developing Countries', 'Family Planning Services', 'Female', 'Goals', 'Health Plan Implementation', 'Health Promotion', 'Health Services Needs and Demand', 'Humans', 'Infant Mortality', 'Infant Welfare', 'Infant, Newborn', 'International Coop... | 22,344,376 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.169'], ['M01.060.406'], ['N02.421.143.130'], ['I01.615.500.300'], ['N02.421.143.401', 'N02.421.800.249'], ['F01.658.500'], ['N03.349.300'], ['I02.233.332.445', 'N02.421.726.407.579'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of genetic variation in LRRTM3 on risk of Alzheimer disease. | OBJECTIVE: To explore the role of leucine-rich repeat transmembrane 3 (LRRTM3) in late-onset Alzheimer disease (AD) by independent genetic epidemiologic and functional studies.METHODS: First, we explored associations between LRRTM3 single-nucleotide polymorphisms and AD in the National Institute on Aging Late-Onset Alz... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Amyloid beta-Protein Precursor', 'Apolipoprotein E3', 'Caribbean Region', 'Chi-Square Distribution', 'Cognition Disorders', 'Female', 'Gene Expression Regulation', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'HEK293 Cells', 'Hispanic Americans'... | 22,393,166 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['D10.532.091.500.500', 'D12.776.070.400.500.500', 'D12.776.521.120.500.500'], ['Z01.107.084'], ['E05.318.740.994.300', 'G17... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social ... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Positive effects of cryopreserved adult or fetal liver cell transplants on hypercholesterolemia and hepatic antioxidant defenses in cholesterol-fed rabbits. | The liver plays a central role in lipid metabolism and the pathophysiology of many lipid disorders leads in turn to liver cell injury. Adult hepatocyte transplants provide well-recognized metabolic support, whilst hepatic stem cells may promote liver regeneration and repair, but in both cases, any clinical application ... | ['Animals', 'Antioxidants', 'Cell Separation', 'Cryopreservation', 'Fetal Tissue Transplantation', 'Hepatocytes', 'Hypercholesterolemia', 'Lipid Peroxidation', 'Lipids', 'Liver', 'Rabbits'] | 17,624,324 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['E02.095.147.725.300', 'E04.936.580... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Short- and long-term effects of a novel paclitaxel coated stent in the porcine coronary model. | BACKGROUND: Drug eluting stents (DES) are unique in allowing sustained release for weeks after a single short intervention. The challenge with DES still remaining is the combination of a biocompatible drug-eluting matrix including an antiproliferative drug showing efficacy and safety in restenosis prevention. The aim o... | ['Angioplasty, Balloon, Coronary', 'Animals', 'Coronary Angiography', 'Coronary Disease', 'Coronary Restenosis', 'Coronary Vessels', 'Disease Models, Animal', 'Drug-Eluting Stents', 'Follow-Up Studies', 'Paclitaxel', 'Probability', 'Random Allocation', 'Risk Factors', 'Survival Rate', 'Swine', 'Swine, Miniature', 'Time... | 18,087,665 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['B01.050'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
3D ultrasound tissue motion tracking using correlation search. | Several methods for ultrasound tissue motion tracking and blood velocity estimation have been proposed and clinically applied. While providing valuable information to the clinician that was not obtainable from B-mode anatomical imaging, these methods still suffer from various fundamental and practical limitations that ... | ['Algorithms', 'Humans', 'Image Processing, Computer-Assisted', 'Movement', 'Transducers', 'Ultrasonography, Doppler'] | 9,921,616 | [['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G07.568', 'G11.427.410'], ['E07.305.812'], ['E01.370.350.850.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessment of metal enrichment and their bioavailability in sediment and bioaccumulation by mangrove plant pneumatophores in a tropical (Zuari) estuary, west coast of India. | Sediment collected from the estuarine mangroves of the Zuari estuary and Cumbharjua canal were analyzed to assess the concentration, contamination and bioavailability of metals. Mangrove pneumatophores were also analyzed to understand the metal bioaccumulation in mangrove plants. The results indicated the variation of ... | ['Biological Availability', 'Ecotoxicology', 'Environmental Monitoring', 'Estuaries', 'Geologic Sediments', 'India', 'Metals', 'Water Pollutants, Chemical', 'Wetlands'] | 27,325,605 | [['G03.787.151', 'G07.690.725.129'], ['H01.158.273.248.500', 'H01.158.891.211', 'H01.277.249.500', 'H02.884.211'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.625.540'], ['G01.311.330', 'G16.500.320'], ['Z01.252.245.393'], ['D01.552'], ['D27.888.284.903.655'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
[Retrospective study of 200 cases of nasopharyngeal carcinoma]. | Nasopharyngeal carcinoma is frequently diagnosed in advanced stages due to the anatomic characteristics of its site of origin and of the inspecificity of many of its clinical manifestations. However, cure rates are directly related with the early diagnosis. In this study of 200 patients affected by this tumor we analys... | ['Carcinoma, Squamous Cell', 'Diagnosis, Differential', 'Humans', 'Nasopharyngeal Neoplasms', 'Otitis Media with Effusion', 'Recurrence', 'Retrospective Studies'] | 12,784,563 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.650', 'C07.550.350.650', 'C07.550.745.650', 'C09.647.710.650', 'C09.775.350.650', 'C09.775.549.650'], ['C09.218.705.663.670'], ['C23.550.291.937'], ['E05.318.372.500.500.500', 'E05.318.37... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Proximal muscle weakness in children. | In as many as half of the children referred to a muscle disease clinic, the original diagnosis is ultimately changed. Five cases histories are reviewed here in which Duchenne muscular dystrophy had been mistakenly diagnosed 3 to 12 years previously and the correct diagnosis was made only after repeat muscle biopsy or b... | ['Biopsy', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Diagnostic Errors', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Muscles', 'Muscular Dystrophies', 'Neuromuscular Diseases'] | 7,454,645 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['E01.354', 'N02.421.450.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
tPA promotes the proliferation of lung fibroblasts and activates the Wnt/â-catenin signaling pathway in idiopathic pulmonary fibrosis. | Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible and the most common fatal interstitial lung disease, which is characterized by damaged alveolar structure, the massive proliferation of fibroblasts and deposition of extracellular matrix (ECM). While the pathogenesis of IPF remains unclear, it ... | ['Animals', 'Cell Proliferation', 'Cells, Cultured', 'Cyclin D1', 'Extracellular Matrix', 'Fibroblasts', 'Glycogen Synthase Kinase 3 beta', 'Idiopathic Pulmonary Fibrosis', 'Mice', 'Mice, Inbred C57BL', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Ribosomal Protein S6 Kinases, 90-kDa', '... | 31,550,972 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['A11.284.295.310'], ['A11.329.228'], ['D05.500.117.875.500', 'D08.811.913.696.620.682.700.429.500.500', 'D08.811.913.696.620.682.700.646.625.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three-dimensional organization of the 30S ribosomal proteins from Escherichia coli. I. Preliminary classification of the proteins. | 30S ribosomal subunits from Escherichia coli were reacted with three protein reagents. After reaction, the ribosomal proteins were extracted and examined; of the 20 proteins known to compose the particle, nine did not react with any of the three reagents. We have tentatively classified these proteins as "internal," and... | ['Bacterial Proteins', 'Centrifugation, Density Gradient', 'Centrifugation, Zonal', 'Chromatography', 'Electrophoresis', 'Escherichia coli', 'Iodoacetates', 'Models, Biological', 'Nitrophenols', 'Ribosomes', 'Trypsin'] | 4,922,288 | [['D12.776.097'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.181.724.336.336', 'E05.196.941.336.419'], ['E05.196.181'], ['E05.196.401', 'E05.301.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.241.081.018.487', 'D02.455.526.581.247'], ['E05.599.395'], ['D02.455.426.559.389.657.566', 'D02.640.743... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cesium and rubidium salts: effects on voluntary intake of ethanol by the rat. | The effects of RbCl and CsCl on voluntary intake of ethanol solution by rats preferring ethanol solution 5% (w/w) over water as the drinking fluid was studied as a function of the dose given and the vehicle injected. Administration of RbCl or CsCl, 0.5 mEq/kg/day or 1.5 mEq/kg/day for three consecutive days, did not al... | ['Alcohol Drinking', 'Animals', 'Cesium', 'Drinking Behavior', 'Feeding Behavior', 'Male', 'Rats', 'Rubidium'] | 733,853 | [['F01.145.317.269'], ['B01.050'], ['D01.268.549.125', 'D01.268.556.165', 'D01.552.528.160', 'D01.552.544.165'], ['F01.145.317'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.268.549.650', 'D01.268.556.800', 'D01.552.528.759', 'D01.552.544.800']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outcomes for Correction of Long-Gap Esophageal Atresia: A 22-Year Experience. | BACKGROUND: Long-gap esophageal atresia (LGEA) precludes immediate primary repair. When delayed primary esophagoesophagostomy (DPE) is not feasible, a reverse gastric tube (RGT) is a potential salvage option. The purpose of this study was to determine if DPE and RGT had both similar short-term and long-term outcomes.ME... | ['Esophageal Atresia', 'Esophagoplasty', 'Female', 'Humans', 'Infant', 'Male', 'Retrospective Studies'] | 32,113,037 | [['C06.198.330', 'C06.405.117.260', 'C16.131.314.330'], ['E04.210.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Possible involvement of natural killer cells in bone marrow graft rejection. | In the present study comparison between Natural killer (NK) cells and cells responsible for rejection of bone marrow grafts was made. Both cell populations were found to be inhibited by cyclophosphamide, silica, carrageenan, and C. parvum. The reactivity of both cell populations occurred late in life and was not expres... | ['Animals', 'Bacterial Vaccines', 'Bone Marrow Transplantation', 'Carrageenan', 'Cyclophosphamide', 'Female', 'Graft Rejection', 'Hematopoietic System', 'Killer Cells, Natural', 'Mice', 'Mice, Inbred Strains', 'Propionibacterium acnes', 'Silicon Dioxide', 'Transplantation, Homologous'] | 203,349 | [['B01.050'], ['D20.215.894.135'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D09.698.152'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['G12.875.545.328'], ['A15.378'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['B01.050.150.900.649.313.992.635.505.500'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
N-3 fatty acids modulate repeated stress-evoked pain chronicity. | N-3 fatty acids, including docosahexaenoic acid (DHA), have a beneficial effect in both pain and psychiatric disorders. In fact, we previously reported that stress-induced pain prolongation might be mediated through the suppression of the G-protein coupled-receptor 40/free fatty acid receptor 1 (GPR40/FFAR1), which is ... | ['Animals', 'Anxiety', 'Brain', 'Chronic Pain', 'Docosahexaenoic Acids', 'Fatty Acids', 'Fatty Acids, Omega-3', 'Female', 'Hyperalgesia', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred ICR', 'Receptors, G-Protein-Coupled', 'Signal Transduction', 'Stress, Psychological'] | 30,831,087 | [['B01.050'], ['F01.470.132'], ['A08.186.211'], ['C23.888.592.612.274'], ['D10.212.302.380.410.210', 'D10.251.355.337.250', 'D10.627.430.450.375'], ['D10.251'], ['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450'], ['C10.597.751.791.400', 'C23.888.592.763.770.400'], ['B01.050.150.900.649.313.992.635.505.500'],... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glycerol oxidation in rat brain: subcellular localization and kinetic characteristics. | The oxidation of [1,3-14C] glycerol to 14CO was measured in slices, whole homogenates, and subcellular fractions of rat brain. In all of these tissue preparations, the Lineweaver-Burk plots of glycerol oxidation were biphasic, yielding two apparent Km and V values. Similar kinetic characteristics were obtained with bra... | ['Animals', 'Brain', 'Carbon Dioxide', 'Glucose', 'Glycerol', 'Glycerol Kinase', 'Guinea Pigs', 'Haplorhini', 'Kinetics', 'Male', 'Mice', 'Mitochondria', 'Oxidation-Reduction', 'Rabbits', 'Rats', 'Species Specificity', 'Subcellular Fractions', 'Swine'] | 6,770,101 | [['B01.050'], ['A08.186.211'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D09.947.875.359.448'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D08.811.913.696.620.275'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Professional ballet dancers have a similar prevalence of articular cartilage defects compared to age- and sex-matched non-dancing athletes. | Ballet exposes the hip joint to repetitive loading in extreme ranges of movement and may predispose a dancer to pain and osteoarthritis (OA). The aims of this study were to compare the prevalence of cartilage defects in professional ballet dancers and athletes and to determine the relationship of clinical signs and sym... | ['Adult', 'Athletes', 'Cartilage, Articular', 'Dancing', 'Female', 'Hip Joint', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Osteoarthritis, Hip', 'Prevalence', 'Range of Motion, Articular', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 27,567,627 | [['M01.060.116'], ['M01.072'], ['A02.165.407.150', 'A02.835.583.192'], ['I03.450.642.287'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C05.550.114.606.400', 'C05.799.613.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.... | ['Named Groups [M]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Isolation and characterization of human monoclonal antibodies to digoxin. | Fab preparations of sheep polyclonal anti-digoxin Abs have proven useful for reversal of the toxic effects of digoxin overdoses in patients. Unfortunately, the use of foreign species proteins in humans is limited because of the potential for immunological responses that include hypersensitivity reactions and acute anap... | ['Animals', 'Antibodies, Monoclonal', 'Antibody Affinity', 'Binding Sites, Antibody', 'Binding, Competitive', 'Digoxin', 'Haptens', 'Humans', 'Hybridomas', 'Immunoglobulin G', 'Immunoglobulin Variable Region', 'Injections, Intraperitoneal', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Mice, Transgenic', 'Species ... | 10,438,974 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.040', 'G12.122.125'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early prednisone therapy in Henoch-Sch?nlein purpura: a randomized, double-blind, placebo-controlled trial. | OBJECTIVE: To evaluate the efficacy of early prednisone therapy in preventing renal and treating extrarenal and renal symptoms in Henoch-Sch?nlein purpura (HSP) in a placebo-controlled trial.STUDY DESIGN: A total of 171 patients (84 treated with prednisone and 87 receiving placebo) were included and followed up for 6 m... | ['Abdominal Pain', 'Adolescent', 'Anti-Inflammatory Agents', 'Arthralgia', 'Child', 'Double-Blind Method', 'Drug Administration Schedule', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Prednisone', 'Prevalence', 'Prospective Studies', 'Purpura, Schoenlein-Henoch', 'Risk Factors', 'Severity of Illness Index', 'Treatme... | 16,887,443 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.057'], ['D27.505.954.158'], ['C05.550.091', 'C23.888.592.612.094', 'F02.830.816.444.350', 'G11.561.790.444.350'], ['M01.060.406'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['B01.050.150.900.649.313.988.4... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Residual behavior and risk assessment of tridemorph in banana conditions. | An efficient method has been developed for determining tridemorph in banana using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The dissipation and terminal residue of tridemorph in banana fields were carried out at good agricultural practice (GAP) conditions. The average recoveries rang... | ['China', 'Chromatography, High Pressure Liquid', 'Food Analysis', 'Food Contamination', 'Half-Life', 'Morpholines', 'Musa', 'Pesticide Residues', 'Risk Assessment', 'Tandem Mass Spectrometry'] | 29,120,807 | [['Z01.252.474.164'], ['E05.196.181.400.300'], ['E05.362', 'J01.576.423.850.100'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['G01.910.405'], ['D03.383.533.640'], ['B01.650.940.800.575.912.250.618.937.555.500'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.200.700'], ['E05.31... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Simultaneous modeling of the Kovats retention indices on OV-1 and SE-54 stationary phases using artificial neural networks. | In this study, a quantitative structure-property relationship technique has been used for the simultaneous prediction of Kovats retention indices for some esters, alcohols, aldehyde and ketones on OV-1 and SE-54 stationary phases, using an artificial neural network (ANN). The best-selected descriptors that appear in th... | ['Chromatography, Gas', 'Models, Chemical', 'Neural Networks, Computer'] | 12,075,931 | [['E05.196.181.349'], ['E05.599.495'], ['G17.485', 'L01.224.050.375.605']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
What do nurses do when they take to the streets? An analysis of psychiatric and mental health nursing interventions in the community. | Little research can be found on nursing practice for populations needing non-traditional mental health care. A descriptive study was done with the nurses on the Community Link Service (CLS), an intensive psychiatric community follow-up program, to identify nursing interventions and the types of situations encountered. ... | ['Case Management', 'Community Health Nursing', 'Community Mental Health Services', 'Follow-Up Studies', 'Humans', 'Mental Disorders', 'Nurse-Patient Relations', "Practice Patterns, Physicians'", 'Psychiatric Nursing'] | 16,335,355 | [['N04.590.233.624.250'], ['H02.478.676.150', 'N02.421.143.150'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F01.829.401.650.600', 'N05.300.660.560'], ['N04.... | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Assessing continuing care needs: findings from the Fife Healthcare Assessment for Placement Project for elderly people. | Previous surveys of elderly patients in different continuing care settings suggest considerable overlap between settings. However, re-analysis of this data in terms of patients' profiles of dependency reveals a somewhat different picture, suggesting that overlap is not such a general phenomenon. Further data from new s... | ['Activities of Daily Living', 'Aged', 'Geriatric Assessment', 'Health Services Needs and Demand', 'Health Services Research', 'Health Surveys', 'Housing for the Elderly', 'Humans', 'Patient Transfer', 'Scotland', 'Skilled Nursing Facilities'] | 8,655,302 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['N03.349.380.420', 'N05.300.450'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
The case for uncontrolled clinical trials: a starting point for the evidence base for CAM. | Clinical research into the effectiveness of any therapy usually progresses in a series of steps that are aimed at providing evidence that will lead to improved patient care. One important early step is the uncontrolled trial. Uncontrolled trials serve several crucial purposes, including establishing firmly that there i... | ['Clinical Trials as Topic', 'Complementary Therapies', 'Ethics, Medical', 'Evidence-Based Medicine', 'Humans', 'Sample Size'] | 11,444,891 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.190'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.762', 'E05.581.500.902', 'N05.715.360.325.692', 'N06.850.520.445.762']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The ability of bovine mammary tissue to synthesize lipids for 96 h when cocultured with liver and adipose tissue. | Explants of bovine mammary, liver, and adipose tissues were cocultured in the same well for 24, 48, 72 or 96 h and their ability to synthesize lipids was measured by the incorporation of [14C]acetate into triglycerides, free fatty acids, and phospholipids. The model was developed to study the effect of bovine somatotro... | ['Adipose Tissue', 'Animals', 'Cattle', 'Female', 'Growth Hormone', 'Insulin-Like Growth Factor I', 'Lipids', 'Liver', 'Mammary Glands, Animal', 'Membrane Lipids', 'Organ Culture Techniques', 'Phospholipids', 'Temperature', 'Time Factors'] | 1,497,862 | [['A10.165.114'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['D10'], ['A03.620'], ['A10.336.482', 'A13.589'], ['D10.570'], ['E05.481.500.484'], ['D10.570.755'], [... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function. | BACKGROUND AND PURPOSE: There is great interest in the development of potentiator drugs to increase the activity of the cystic fibrosis transmembrane conductance regulator (CFTR) in cystic fibrosis. We tested the ability of several anions to potentiate CFTR activity by a novel mechanism.EXPERIMENTAL APPROACH: Patch cla... | ['Animals', 'Cell Line', 'Cobalt', 'Cricetinae', 'Cyanides', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Humans', 'Iridium', 'Mutation', 'Platinum Compounds'] | 22,612,315 | [['B01.050'], ['A11.251.210'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['B01.050.150.900.649.313.992.635.075.250'], ['D01.248.497.158.291', 'D01.625.400.100'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bimatoprost versus Mometasone Furoate in the Treatment of Scalp Alopecia Areata: A Pilot Study. | BACKGROUND: Alopecia areata (AA) is an immune-mediated disease that targets anagen hair follicles. Despite various therapeutic options, there is no cure for AA. Prostaglandin analogues have been recognized as being capable of inducing hypertrichosis.OBJECTIVE: To compare the efficacy and safety of bimatoprost to those ... | ['Administration, Cutaneous', 'Adult', 'Alopecia Areata', 'Bimatoprost', 'Dermatologic Agents', 'Female', 'Hair', 'Humans', 'Male', 'Middle Aged', 'Mometasone Furoate', 'Pilot Projects', 'Prospective Studies', 'Scalp', 'Severity of Illness Index', 'Single-Blind Method', 'Skin Cream', 'Young Adult'] | 25,765,294 | [['E02.319.267.120.060'], ['M01.060.116'], ['C17.800.329.937.122.147'], ['D02.065.141', 'D10.251.355.255.550.775.500.175.250', 'D23.469.050.175.725.775.500.175.250', 'D23.469.700.670.175.250'], ['D27.505.954.444'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D04.210.500.745.432.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
RhoA-sensitive trafficking of muscarinic acetylcholine receptors. | The clathrin-mediated sequestration pathway is used by non-G protein-coupled receptors (e.g., transferrin receptors) and a large number of G protein-coupled receptors, including beta-2 adrenoceptors and various muscarinic acetylcholine receptor (mAChR) subtypes. Recently, the ubiquitously expressed small GTPase RhoA ha... | ['Biological Transport', 'Cell Line, Transformed', 'Clathrin', 'GTP-Binding Proteins', 'Humans', 'Receptor, Muscarinic M1', 'Receptor, Muscarinic M2', 'Receptors, Cell Surface', 'Receptors, Muscarinic', 'rhoA GTP-Binding Protein'] | 9,862,750 | [['G03.143'], ['A11.251.210.172'], ['D12.776.543.990.200'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.695.475.100', 'D12.776.543.750.720.360.500.099'], ['D12.776.543.750.695.475.200', 'D12.776.543.750.720.360.500.200'], ['D12.776.543.750'], ['D12.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seasonal variation, weather and behavior in day-care children: a multilevel approach. | This study analyzes the effect of weather variables, such as solar radiation, indoor and outdoor air temperature, relative humidity and time spent outdoor, on the behavior of 2-year-old children and their affects across different seasons: winter, spring and summer. Participants were a group of 61 children (33 males and... | ['Aggression', 'Child Behavior', 'Child, Preschool', 'Day Care, Medical', 'Environment', 'Female', 'Frustration', 'Humans', 'Italy', 'Male', 'Seasons', 'Weather'] | 23,238,531 | [['F01.145.126.125', 'F01.145.813.045'], ['F01.145.179'], ['M01.060.406.448'], ['E02.760.246', 'N02.421.585.246'], ['G16.500.275', 'N06.230'], ['F01.470.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G16.500.275.063.725',... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pulmonary veno-occlusive disease: diagnostic and therapeutic alternatives. | Pulmonary veno-occlusive disease (PVOD) is a rare cause of pulmonary hypertension. Surgical biopsy was usually required for diagnostic confirmation. However, the morbidity, mortality and limited benefit of this procedure have generated discussion regarding noninvasive diagnostic techniques. We present the case of a fem... | ['Biopsy', 'Bronchoalveolar Lavage', 'Bronchoscopy', 'Endothelin Receptor Antagonists', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Lung', 'Middle Aged', 'Pulmonary Veno-Occlusive Disease', 'Receptors, Endothelin'] | 18,982,212 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.927.100'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['D27.505.519.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Challenges to using an electronic personal health record by a low-income elderly population. | BACKGROUND: Electronic personal health records (PHRs) are increasingly recognized and used as a tool to address various challenges stemming from the scattered and incompatible personal health information that exists in the contemporary US health care system. Although activity around PHR development and deployment has i... | ['Adult', 'Aged', 'Aged, 80 and over', 'Delivery of Health Care', 'Education, Nursing, Graduate', 'Electronic Health Records', 'Female', 'Health Services for the Aged', 'Humans', 'Internet', 'Male', 'Medical Records Systems, Computerized', 'Middle Aged', 'Patient Participation', 'Poverty', 'Young Adult'] | 19,861,298 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N04.590.374', 'N05.300'], ['I02.358.337.450', 'I02.358.462.565'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['N02.421.320'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Interferon consensus sequence-binding protein is constitutively expressed and differentially regulated in the ocular lens. | Interferon signaling is mediated by STATs and interferon regulatory factor (IRF) families of transcription factors. Ten distinct IRFs have been described and most are expressed in a variety of cells except for interferon consensus sequence-binding protein (ICSBP) and lymphoid-specific IRF/Pip that are thought to be exc... | ['Animals', 'Cells, Cultured', 'Consensus Sequence', 'DNA-Binding Proteins', 'Epithelial Cells', 'Gene Expression Regulation', 'Immunohistochemistry', 'Interferon Regulatory Factors', 'Interferon-gamma', 'Lens, Crystalline', 'Mice', 'Mice, Inbred BALB C', 'Repressor Proteins', 'STAT1 Transcription Factor', 'Trans-Activ... | 10,092,656 | [['B01.050'], ['A11.251'], ['G02.111.570.580.175'], ['D12.776.260'], ['A11.436'], ['G05.308'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Addison's disease as a rare cause of chronically elevated liver enzymes]. | Common causes of chronically elevated serum liver enzymes include fatty liver disease, chronic viral hepatitis, autoimmune hepatitis, or hereditary metabolic disorders. Adrenocortical insufficiency can also cause elevated liver enzymes. Since 1990 only 11 cases have been reported. We here report a 52-year-old man with ... | ['Addison Disease', 'Fludrocortisone', 'Humans', 'Hydrocortisone', 'Liver', 'Liver Diseases', 'Male', 'Middle Aged', 'Rare Diseases', 'Treatment Outcome'] | 16,456,760 | [['C19.053.500.263', 'C20.111.163'], ['D04.210.500.745.745.654.600.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['A03.620'], ['C06.552'], ['M01.060.116.630'], ['C23.550.291.906'], ['E01.789.800', 'N04.761.559.590.800', 'N0... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Lateral arm free flap transfer to cover traumatic hand injuries]. | The advantages of free flaps over distant pedicled flaps in hand reconstruction are well documented. They often require only a single operation, do not depend on local conditions of the wound and permit early physiotherapy. The lateral arm free flap is essentially suitable for reconstruction of the hand. It is thin, po... | ['Adult', 'Arm', 'Hand Injuries', 'Humans', 'Male', 'Surgical Flaps'] | 1,572,576 | [['M01.060.116'], ['A01.378.800.075'], ['C26.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The novel acidophilic structure of the killer toxin from halotolerant yeast demonstrates remarkable folding similarity with a fungal killer toxin. | BACKGROUND: Several strains of yeasts and fungi produce proteinous substances, termed killer toxins, which kill sensitive strains. The SMK toxin, secreted by the halotolerant yeast Pichia farinosa KK1 strain, uniquely exhibits its maximum killer activity under conditions of acidic pH and high salt concentration. The to... | ['Amino Acid Sequence', 'Crystallization', 'Crystallography, X-Ray', 'Dimerization', 'Fungal Proteins', 'Hydrogen Bonding', 'Killer Factors, Yeast', 'Models, Molecular', 'Molecular Sequence Data', 'Mycotoxins', 'Pichia', 'Protein Folding', 'Protein Processing, Post-Translational', 'Protein Structure, Secondary', 'Prote... | 9,016,714 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['G02.206', 'G03.230'], ['D12.776.354'], ['G02.282'], ['D12.776.354.374', 'D23.946.587.531'], ['E05.599.595'], ['L01.453.245.667'], ['D23.946.587'], ['B01.300.107.795.700', 'B01.300.930.600'], ['G01.154.651', 'G02.111.688'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A structure-based multiple sequence alignment of all class I aminoacyl-tRNA synthetases. | The superimposable dinucleotide fold domains of MetRS, GlnRS and TyrRS define structurally equivalent amino acids which have been used to constrain the sequence alignments of the 10 class I aminoacyl-tRNA synthetases (aaRS). The conservation of those residues which have been shown to be critical in some aaRS enables to... | ['Amino Acid Sequence', 'Amino Acyl-tRNA Synthetases', 'Escherichia coli', 'Methionine-tRNA Ligase', 'Models, Chemical', 'Molecular Sequence Data', 'Protein Conformation', 'Sequence Alignment', 'Sequence Homology, Amino Acid'] | 7,647,112 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.464.263.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.464.263.200.600'], ['E05.599.495'], ['L01.453.245.667'], ['G02.111.570.820.709'], ['E05.393.751'], ['G02.111.810.200', 'G05.810.200']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Strategies for pharmacologic treatment of high functioning autism and Asperger syndrome. | The treatment of complex, polymorphous disorders like HFA/AS always brings a particular challenge to pharmacotherapy. Additionally, the specific characteristics presented by HFA/AS introduce unique complications to patient care and place unusual demands on a clinician's skill and experience. To provide safe and effecti... | ['Adolescent', 'Asperger Syndrome', 'Autistic Disorder', 'Child', 'Combined Modality Therapy', 'Female', 'Humans', 'Intelligence', 'Male', 'Patient Care Team', 'Psychotropic Drugs'] | 12,512,397 | [['M01.060.057'], ['F03.625.164.113.250'], ['F03.625.164.113.500'], ['M01.060.406'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['N04.590.715'], ['D27.505.954.427.700']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Safety, efficacy, and clinical applicability of pulmonary vein isolation with circular multi-electrode ablation systems: PVAC® vs. nMARQ™ for atrial fibrillation ablation. | AIMS: We compare our experience with available circular multi-electrode catheters for atrial fibrillation (AF) ablation: PVAC(®), a phased radiofrequency system, and nMARQ™, an irrigated tip-CARTO-based technology.METHODS AND RESULTS: Prospective observational study of 175 consecutive patients with follow-up duration o... | ['Aged', 'Atrial Fibrillation', 'Catheter Ablation', 'Electrodes, Implanted', 'Equipment Design', 'Equipment Failure Analysis', 'Female', 'Fluoroscopy', 'Follow-Up Studies', 'Heart Atria', 'Humans', 'Israel', 'Male', 'Middle Aged', 'Prospective Studies', 'Pulmonary Veins', 'Treatment Outcome'] | 26,589,623 | [['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['E02.808.750.500', 'E04.014.760.500'], ['E07.305.250.319', 'E07.695.202'], ['E05.320'], ['E05.325.192'], ['E01.370.350.700.225'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A07.541.358'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Role of pharmacological aids and social supports in smoking cessation associated with Quebec's 2000 Quit and Win campaign. | BACKGROUND: This evaluation of the 2000 Quit and Win campaign in the province of Quebec, Canada, assessed the use and effectiveness of pharmacological aids, social support, and support resources (clinic program, support groups, books, telephone support) among contest participants. The reach of the contest was 1.3% of a... | ['Adolescent', 'Adult', 'Drug Therapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Quebec', 'Smoking Cessation', 'Social Support'] | 15,066,370 | [['M01.060.057'], ['M01.060.116'], ['E02.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.567.176.791'], ['F01.145.488.732'], ['I01.880.853.500.600']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Shoulder pain: pathogenesis, diagnosis and management. | Shoulder pain is a common musculoskeletal problem that can have a significant effect on people's activities of daily living and quality of life. Nurses have a central role in the assessment, management and follow up of patients undergoing conservative and surgical treatments. Understanding the often complex and chronic... | ['Analgesics', 'Humans', 'Pain Management', 'Patient-Centered Care', 'Practice Guidelines as Topic', 'Shoulder Pain'] | 24,471,638 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.745', 'N04.590.607.500'], ['N04.590.233.727.407'], ['N04.761.700.350.650', 'N05.700.350.650'], ['C05.550.091.700', 'C23.888.592.612.094.700', 'F02.830.816.444.350.500', 'G11.561.790.444.350.500']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Biochemical characteristics of AtFAR2, a fatty acid reductase from Arabidopsis thaliana that reduces fatty acyl-CoA and -ACP substrates into fatty alcohols. | Fatty alcohols and derivatives are important for proper deposition of a functional pollen wall. Mutations in specific genes encoding fatty acid reductases (FAR) responsible for fatty alcohol production cause abnormal development of pollen. A disrupted AtFAR2 (MS2) gene in Arabidopsis thaliana results in pollen developi... | ['Acyl Carrier Protein', 'Acyl Coenzyme A', 'Aldehyde Oxidoreductases', 'Arabidopsis', 'Arabidopsis Proteins', 'Fatty Alcohols', 'Hydrogen-Ion Concentration', 'Kinetics', 'Plant Leaves', 'Serum Albumin, Bovine', 'Substrate Specificity', 'Tobacco'] | 27,274,541 | [['D12.776.157.050'], ['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['D08.811.682.657.163'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D02.033.415', 'D10.289'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['A18.024.812'], ['D12.776.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nucleotide and nucleic acid metabolism in rat thymocytes during cell cycle progression. | A complete cell cycle of mature, concanavalin A (Con A) stimulated rat thymocytes was documented by analyzing the cell number as well as the content and synthesis of DNA and RNA. Cell cycle progression is accompanied by an elevation of class I, II and III RNA polymerase activities (about 10-fold) in the S phase maximum... | ['Animals', 'Cell Cycle', 'Concanavalin A', 'DNA', 'DNA-Directed RNA Polymerases', 'Female', 'Kinetics', 'Lymphocyte Activation', 'Nucleotides', 'Phosphoribosyl Pyrophosphate', 'RNA', 'Rats', 'T-Lymphocytes', 'Thymus Gland'] | 1,718,437 | [['B01.050'], ['G04.144'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D13.444.308'], ['D08.811.913.696.445.735.270'], ['G01.374.661', 'G02.111.490'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['D09.408.620', 'D13.695'], ['D09.894.643.650'], ['D13.444.735'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
To swim or not to swim: A population-level model of Xenopus tadpole decision making and locomotor behaviour. | We present a detailed computational model of interacting neuronal populations that mimic the hatchling Xenopus tadpole nervous system. The model includes four sensory pathways, integrators of sensory information, and a central pattern generator (CPG) network. Sensory pathways of different modalities receive inputs from... | ['Animals', 'Behavior, Animal', 'Decision Making', 'Larva', 'Locomotion', 'Models, Neurological', 'Motor Neurons', 'Nerve Net', 'Neural Inhibition', 'Swimming', 'Xenopus'] | 28,720,508 | [['B01.050'], ['F01.145.113'], ['F02.463.785.373'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G07.568.500', 'G11.427.410.568'], ['E05.599.395.642'], ['A08.675.655.500', 'A11.671.655.500'], ['A08.511'], ['G07.265.755', 'G11.561.616'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I03.350.875', 'I03.450.642.845... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[The current status of organ transplantation: the role of xenotransplantation?]. | In the last few years, transplantation was an area of intense research activity. However, there is a worldwide shortage of donor organs for clinical transplantations. Currently, interest in xenotransplantation research is growing not only because of the increased demand for organs but also because of advances in molecu... | ['Animals', 'Genetic Techniques', 'Graft Rejection', 'Graft Survival', 'Humans', 'Immunologic Techniques', 'Molecular Biology', 'Organ Transplantation', 'Research', 'Tissue Donors', 'Tissue and Organ Procurement', 'Transplantation Immunology', 'Transplantation, Heterologous'] | 9,564,229 | [['B01.050'], ['E05.393'], ['G12.875.545.328'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478'], ['H01.158.201.636', 'H01.158.273.343.595', 'H01.181.122.650'], ['E04.936.450'], ['H01.770.644'], ['M01.898'], ['N02.421.911'], ['G12.875'], ['E04.936.764']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Fractal scaling mechanisms in biomembranes. Oscillations in the lateral diffusion coefficient. | A modified model of the Cohen-Turnbull free volume theory for lateral transport processes in biomembranes is presented. The model which is based on renormalization group theoretical concepts incorporates fractal rather than Markovian diffusion kinetics. It predicts harmonic oscillations in the lateral diffusion coeffic... | ['Cell Membrane', 'Diffusion', 'Membrane Fluidity', 'Membrane Proteins', 'Models, Theoretical', 'Periodicity'] | 2,924,739 | [['A11.284.149'], ['G01.202', 'G02.196'], ['G01.154.500', 'G02.111.550', 'G04.570'], ['D12.776.543'], ['E05.599'], ['G01.910.645', 'G07.180.562']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
C-peptide and insulin secretion in diabetes mellitus treated with oral hypoglycaemic agents or diet alone. A 3 years epidemiological cohort study on the Island of Falster, Denmark. | In a 3 yr epidemiological cohort study of 273 diabetics treated with oral hypoglycaemic agents (OHA) and 60 diet-treated diabetics the predictive value of fasting plasma C-peptide levels was assessed with the attempt to discriminate between insulin dependence and non-insulin dependence. Serum insulin, blood glucose, ha... | ['Adult', 'Blood Glucose', 'Body Weight', 'C-Peptide', 'Diabetes Mellitus', 'Diet, Diabetic', 'Female', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Insulin Secretion', 'Male', 'Middle Aged'] | 3,301,161 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C18.452.394.750', 'C19.246'], ['E02.642.249.240', 'G07.203.650.240.240'], ['B01.050.150.90... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Fate of Spacers in the Treatment of Periprosthetic Joint Infection. | BACKGROUND: Two-stage exchange arthroplasty remains the preferred method to treat periprosthetic joint infection. The aim of this study was to investigate the clinical course of periprosthetic joint infection following resection arthroplasty and insertion of a spacer.METHODS: Our institutional database was used to iden... | ['Aged', 'Arthrodesis', 'Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Confidence Intervals', 'Databases, Factual', 'Device Removal', 'Female', 'Follow-Up Studies', 'Humans', 'Kaplan-Meier Estimate', 'Logistic Models', 'Male', 'Middle Aged', 'Prosthesis-Related Infections', 'Reoperation', 'Retros... | 26,378,265 | [['M01.060.116.100'], ['E04.555.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.199'], ['E05.318.372.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The effects of grommet insertion on Eustachian tube function. | A prospective study on the effect of grommet insertion on the passive Eustachian tube opening pressure was undertaken in children's ears with otitis media with effusion. After an initial immediate improvement following aspiration of the middle ear no further change in Eustachian tube function occurred over 4 subsequent... | ['Child', 'Child, Preschool', 'Eustachian Tube', 'Humans', 'Middle Ear Ventilation', 'Otitis Media with Effusion', 'Tympanic Membrane'] | 8,877,219 | [['M01.060.406'], ['M01.060.406.448'], ['A09.246.397.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.579.592', 'E04.580.450.472'], ['C09.218.705.663.670'], ['A09.246.272.702']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultraviolet difference spectroscopy study of peanut lectin binding to Mono- and disaccharides. | Ultraviolet difference spectroscopy was used to study the interaction of peanut (Arachis hypogaea) lectin with complementary carbohydrates. A correlation was observed between variations of ultraviolet spectra during the binding of sugars to the lectin and the specificity and the strength of the binding. The association... | ['Binding Sites', 'Chemical Phenomena', 'Chemistry', 'Disaccharides', 'Lactose', 'Lectins', 'Monosaccharides', 'Peanut Agglutinin', 'Spectrophotometry, Ultraviolet'] | 7,126,638 | [['G02.111.570.120'], ['G02'], ['H01.181'], ['D09.698.629.305', 'D09.947.750'], ['D09.698.629.305.340', 'D09.947.750.340'], ['D12.776.503'], ['D09.947.875'], ['D12.776.503.499.625', 'D12.776.765.678.625'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Content of total immunoglobulin E in patients with acute appendicitis]. | The authors investigated the content of total immunoglobulin E in 34 patients with different forms of acute appendicitis. Higher level of immunoglobulin E was revealed in 19 patients. All the patients had destructive forms of appendicitis, in the third of the patients they were complicated by the development of local p... | ['Acute Disease', 'Appendicitis', 'Humans', 'Immunoenzyme Techniques', 'Immunoglobulin E', 'Peritonitis', 'Postoperative Complications', 'Suppuration', 'Surgical Wound Infection'] | 11,496,488 | [['C23.550.291.125'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['C01.463.600', 'C06.844... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High dietary cholesterol masks type 2 diabetes-induced osteopenia and changes in bone microstructure in rats. | Type 2 diabetes mellitus (T2DM) often occurs concurrently with high blood cholesterol or dyslipidemia. Although T2DM has been hypothesized to impair bone microstructure, several investigations showed that, when compared to age-matched healthy individuals, T2DM patients had normal or relatively high bone mineral density... | ['Animals', 'Bone Density', 'Bone Diseases, Metabolic', 'Bone and Bones', 'Cholesterol, Dietary', 'Delayed Diagnosis', 'Diabetes Mellitus, Type 2', 'Dyslipidemias', 'Female', 'Growth Plate', 'Lipid Metabolism', 'Osteoblasts', 'Osteoclasts', 'Rats', 'Rats, Inbred Strains', 'X-Ray Microtomography'] | 25,200,330 | [['B01.050'], ['G11.427.100'], ['C05.116.198', 'C18.452.104'], ['A02.835.232', 'A10.165.265'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['C18.452.394.750.149', 'C19.246.300'], ['C18.452.584.500'], ['A02.835.232.251.352'], ['G03.458'], ['A1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dynamics of viral hepatitis B epidemiological process in Plovdiv region. | Registration of viral hepatitis cases by type started in 1982 in Bulgaria, and in August 1991 Bulgaria launched a mass immunisation programme to vaccinate infants against hepatitis B. The objective of this dissertation thesis is to study the epidemiological status of hepatitis B virus (HBV) infection in Plovdiv region ... | ['Bulgaria', 'Hepatitis B', 'Hepatitis B Surface Antigens', 'Hepatitis B Vaccines', 'Humans', 'Incidence', 'Renal Dialysis', 'Vaccination'] | 24,191,410 | [['Z01.542.248.180'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D23.050.327.495.500.475'], ['D20.215.894.899.955.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.52... | ['Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Immune enhancing effects of Lactobacillus acidophilus LAFTI L10 and Lactobacillus paracasei LAFTI L26 in mice. | The immune enhancing properties of Lactobacillus acidophilus LAFTI L10 and Lactobacillus paracasei LAFTI L26 in mice were investigated. Each mouse (BALB/c) was orally fed with cultures of either L. acidophilus or L. paracasei at 10(8) CFU/50 mul per day for 14 days. The effect of these strains on immunoglobulin A, inte... | ['Animals', 'Colony Count, Microbial', 'Enzyme-Linked Immunosorbent Assay', 'Fluorescent Antibody Technique, Direct', 'Immunoglobulin A', 'Interferon-gamma', 'Interleukin-10', 'Intestine, Small', 'Lactobacillus', 'Lactobacillus acidophilus', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Random Allocation'] | 17,134,782 | [['B01.050'], ['E01.370.225.875.220', 'E05.200.875.220'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.607.512.240.300', 'E01.370.225.750.551.512.240.300', 'E05.200.500.607.512.240.300', 'E05.200.750.551.512.240.300', 'E05.478.583... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of cytidine on the modification of phospholipid metabolism induced by ischemia. | [1-14C-]Arachidonic acid was injected into the lateral ventricle of the gerbils (meriones unguiculatus) two hours before producing brain ischemia by the bilateral ligation of the carotid arteries. Ten minutes before the carotid ligation a group of animals received an additional intraventricular injection of cold cytidi... | ['Animals', 'Arachidonic Acid', 'Arachidonic Acids', 'Brain', 'Brain Ischemia', 'Cytidine', 'Diglycerides', 'Gerbillinae', 'Injections, Intraventricular', 'Male', 'Phospholipids', 'Plasmalogens'] | 3,108,688 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D03.383.742.680.245', 'D13.570.685.245', 'D13.570.800.286'], ['D10.351.303'], ['B01.050.150.900.649.313.992.635.300'], ['E02.319.267.530.55... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insights into the alteration of osteoblast mechanical properties upon adhesion on chitosan. | Cell adhesion on substrates is accompanied by significant changes in shape and cytoskeleton organization, which affect subsequent cellular and tissue responses, determining the long-term success of an implant. Alterations in osteoblast stiffness upon adhesion on orthopaedic implants with different surface chemical comp... | ['Actin Cytoskeleton', 'Aged', 'Cell Adhesion', 'Cells, Cultured', 'Chitosan', 'Coated Materials, Biocompatible', 'Elastic Modulus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteoblasts'] | 24,987,701 | [['A11.284.430.214.190.750.050'], ['M01.060.116.100'], ['G04.022'], ['A11.251'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D25.130.420', 'J01.637.051.130.420'], ['G01.374.590.605'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A11.329.629']] | ['Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Echocardiographic detection of an intact aneurysm in a horse. | Two-dimensional real-time echocardiographic examination of a 3-year-old Thoroughbred gelding with pleuropneumonia revealed an intact aneurysm of the right sinus of Valsalva, which was confirmed at postmortem examination. The horse had no clinical signs associated with the aneurysm. | ['Animals', 'Aortic Aneurysm', 'Auscultation', 'Echocardiography', 'Horse Diseases', 'Horses', 'Male', 'Pleuropneumonia', 'Punctures', 'Sinus of Valsalva', 'Thorax'] | 2,211,328 | [['B01.050'], ['C14.907.055.239', 'C14.907.109.139'], ['E01.370.600.060'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C01.748.582.473', 'C01.748.610.473', 'C08.381.677.473', 'C08.528.735.473', 'C08.730.582.473', 'C08.730.610.473'], ['E0... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of rat urinary HPLC-UV profiling for metabonomic study on Liuwei Dihuang Pills. | Since urine contains thousands of metabolites, there are no universal analytical techniques to analyze these compounds simultaneously. Therefore, a readily obtained and simple sample pretreatment high-performance liquid chromatography (HPLC) with ultraviolet (UV) detection urinary profiling with good reproducibility wa... | ['Animals', 'Chromatography, High Pressure Liquid', 'Dosage Forms', 'Drugs, Chinese Herbal', 'Gene Expression Profiling', 'Male', 'Medicine, Chinese Traditional', 'Metabolome', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Reproducibility of Results', 'Spectrophotometry, Ultraviolet', 'Urinalysis'] | 19,081,221 | [['B01.050'], ['E05.196.181.400.300'], ['D26.255', 'E05.916.250'], ['D20.215.784.500.350', 'D26.335'], ['E05.393.332'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['G03.500'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Advantages of the enlarged middle cranial fossa approach in acoustic neurinoma surgery. A review. | Utilizing an enlarged middle cranial fossa approach to the cerebello-pontine angle without destruction of the labyrinth or cochlea the authors have since 1981 operated on 263 unilateral acoustic neurinomas. Tumour sizes ranged between 3 mm intrameatal and 35 mm within the cerebello-pontine angle. Complete tumour remova... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Deafness', 'Evoked Potentials, Auditory, Brain Stem', 'Facial Nerve', 'Hearing', 'Humans', 'Middle Aged', 'Monitoring, Intraoperative', 'Neuroma, Acoustic', 'Petrous Bone', 'Postoperative Complications', 'Retrospective Studies', 'Semicircular Canals', 'Skull', 'Vest... | 1,441,980 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.80... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Three-dimensional quantitative assessment of lesion response to MR-guided high-intensity focused ultrasound treatment of uterine fibroids. | RATIONALE AND OBJECTIVES: To investigate the response after magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) treatment of uterine fibroids (UF) using a three-dimensional (3D) quantification of total and enhancing lesion volume (TLV and ELV, respectively) on contrast-enhanced MRI (ceMRI) scans.METHO... | ['Adult', 'Cohort Studies', 'Contrast Media', 'Feasibility Studies', 'Female', 'Follow-Up Studies', 'High-Intensity Focused Ultrasound Ablation', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Leiomyoma', 'Magnetic Resonance Imaging, Interventional', 'Middle Aged', 'Remission Induction'... | 26,160,057 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D27.505.259.500', 'D27.720.259'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E02.565.280.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Micromethod for the determination of 3-beta-HSD activity in cultured cells. | A modified radioassay for the determination of the 3 beta-hydroxy-delta 5-steroid dehydrogenase (3-beta-HSD) is described. The assay is based on the conversion of [3H]pregnenolone to [3H]progesterone followed by a digitonin precipitation step. The method was applied to neurons, glial cells, C6 glioma cells and adrenal ... | ['3-Hydroxysteroid Dehydrogenases', 'Animals', 'Brain', 'Cells, Cultured', 'Mice', 'Mice, Inbred BALB C', 'Neuroglia', 'Neurons', 'Tritium'] | 2,811,376 | [['D08.811.682.047.436.350'], ['B01.050'], ['A08.186.211'], ['A11.251'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['A08.637', 'A11.650'], ['A08.675', 'A11.671'], ['D01.268.406.875', 'D01.362.340.875', 'D01.496.749.925']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Flavobacterium antarcticum sp. nov., a novel psychrotolerant bacterium isolated from the Antarctic. | A yellow-pigmented, Gram-negative and aerobic bacterial strain, designated AT1026(T), was isolated from a terrestrial sample from the Antarctic. Results of 16S rRNA gene sequence analysis indicated that the Antarctic isolate belonged to the genus Flavobacterium, with the highest sequence similarity to Flavobacterium te... | ['Antarctic Regions', 'Bacterial Typing Techniques', 'Cold Temperature', 'DNA, Bacterial', 'DNA, Ribosomal', 'Fatty Acids', 'Flavobacterium', 'Molecular Sequence Data', 'Phenotype', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Soil Microbiology'] | 15,774,636 | [['Z01.158'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D13.444.308.212'], ['D13.444.308.475'], ['D10.251'], ['B03.440.080.190.250', 'B03.440.400.425.310.250'], ['L01.453.... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Highly sensitive detection of hybridization of oligonucleotides to specific sequences of nucleic acids by application of fluorescence resonance energy transfer. | We show a new application of fluorescence resonance energy transfer (FRET) in two stages to detect specific sequences of nucleic acids. In the first stage, two fluorescently tagged oligonucleotides hybridize with a complementary target molecule to produce FRET. The sequences of the oligonucleotides and spectral propert... | ['Binding, Competitive', 'Energy Transfer', 'Fluorescence Polarization', 'Nucleic Acid Hybridization', 'Oligonucleotide Probes', 'Spectrometry, Fluorescence', 'Titrimetry'] | 10,805,160 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['E05.196.712.516.600.390'], ['E05.393.661', 'G02.111.611'], ['D13.444.600.601', 'D27.505.259.750.600.650', 'D27.720.470.530.600.650'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['E05.196.922']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Associations between working memory, health literacy, and recall of the signs of stroke among older adults. | Stroke remains a major cause of mortality and disability among older adults. Although early treatment after stroke is known to reduce both mortality and disability, the first step in seeking early treatment is dependent on the rapid recognition of the signs of stroke. Recall of the signs of stroke may be dependent on f... | ['Aged', 'Aged, 80 and over', 'Diagnostic Self Evaluation', 'Female', 'Health Literacy', 'Humans', 'Male', 'Memory, Short-Term', 'Mental Recall', 'New York City', 'Pamphlets', 'Stroke'] | 22,955,236 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.360', 'F01.752.747.792.220'], ['I02.233.332.186.500', 'L01.143.450.500', 'N02.421.726.407.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463.425.540.641'], ['Z01.107.567.875.350.530.530', 'Z01.107.567.875.500.530.530', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Quality of Life in Painful Peripheral Neuropathies: A Systematic Review. | Objective: Neuropathic pain is a common presenting complaint of patients with peripheral neuropathy (PN) and is considered one of the most disabling neuropathic symptoms, with detrimental effects on patients' quality of life (QoL). The aim of this review was to overview the current literature that focuses on QoL in pai... | ['Humans', 'Neuralgia', 'Pain Management', 'Quality of Life'] | 31,249,636 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829.600', 'C23.888.592.612.664'], ['E02.745', 'N04.590.607.500'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
The absorption characterization effects and mechanism of Radix Angelicae dahuricae extracts on baicalin in Radix Scutellariae using in vivo and in vitro absorption models. | ETHNOPHARMACOLOGICAL RELEVANCE: Angelicae Dahurica(Hoffm.)Benth.&Hook.f.ex Franch.&Sav combined with Scutellaria baicalensis Georgi. has been widely used as herb-pairs in traditional Chinese medicine (TCM) to treat migraine headache and cataract, but the underlying compatibility mechanism of the two herbs remains unkno... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Angelica', 'Animals', 'Coumarins', 'Drugs, Chinese Herbal', 'Female', 'Flavonoids', 'Herb-Drug Interactions', 'In Vitro Techniques', 'Intestinal Absorption', 'Intestinal Mucosa', 'Male', 'Oils, Volatile', 'Rats', 'Rats, Sprague-Dawley', 'Scutellaria baicalens... | 22,023,882 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['B01.650.940.800.575.912.250.075.088'], ['B01.050'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCâ/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1. | High mobility group box 1 (HMGB1), an important inflammatory mediator, is actively secreted by immune cells and some non-immune cells or passively released by necrotic cells. HMGB1 has been implicated in many inflammatory diseases. Our previous published data demonstrated that HMGB1 was up-regulated in heart tissue or ... | ['Animals', 'Autoimmune Diseases', 'Disease Models, Animal', 'Extracellular Signal-Regulated MAP Kinases', 'Fibrillar Collagens', 'HMGB1 Protein', 'MAP Kinase Signaling System', 'Mice, Inbred BALB C', 'Myocarditis', 'Myofibroblasts', 'Osteopontin', 'Protein Kinase C beta', 'Up-Regulation'] | 24,912,759 | [['B01.050'], ['C20.111'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['D05.750.078.280.300', 'D12.776.860.300.250.300'], ['D12.776.260.356.300', 'D12.776.660.235.400.600.300', 'D12.776.664.235.400.600.300'], ['G02.111.820.560', ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antihypertensives and myocardial infarction risk: the modifying effect of history of drug use. | PURPOSE: Confounding by indication is common in observational studies of outcomes that treatment is intended to affect. In light of the stepped-care approach to hypertension management, we reexamined the controversy around myocardial infarction (MI) risk in relation to antihypertensive agents by considering past drug h... | ['Adrenergic beta-Antagonists', 'Adult', 'Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Antihypertensive Agents', 'Calcium Channel Blockers', 'Case-Control Studies', 'Cohort Studies', 'Digoxin', 'Drug Prescriptions', 'Drug Utilization', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Myocardial Infarc... | 11,760,488 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.389.745.085'], ['D27.505.954.411.162'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Time effects, cultural influences, and individual differences in crew behavior during the Mars-500 experiment. | INTRODUCTION: This note provides an overview of salient factors that could have an impact on the behavior of a crew in an isolated and confined environment during a very long-term adaptive process. We present the Mars-500 experiment, which took place in Moscow, Russia, over 520 d from June 5, 2010, to November 4, 2011.... | ['Adult', 'Communication', 'Cross-Cultural Comparison', 'Culture', 'Ecological Systems, Closed', 'Factor Analysis, Statistical', 'Humans', 'Male', 'Russia', 'Space Flight'] | 24,261,062 | [['M01.060.116'], ['F01.145.209', 'L01.143'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['I01.076.201.450', 'I01.880.853.100'], ['G16.500.275.157.240', 'N06.230.124.240', 'N06.230.150.225'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.2... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, In... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Statistical literacy in obstetricians and gynecologists. | The Obstetrician-Gynecologist Statistical Literacy Questionnaire (OGSLQ) was designed to examine physicians' understanding of various number tasks that are relevant to obstetrician-gynecologists (ob-gyns) practice. Forty-seven percent of the nationally representative, practicing ob-gyns responded. Physicians did poorly... | ['Adult', 'Female', 'Gynecology', 'Humans', 'Male', 'Obstetrics', 'Physicians', 'Professional Competence', 'Statistics as Topic'] | 22,292,459 | [['M01.060.116'], ['H02.403.763.750', 'H02.403.810.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.450'], ['M01.526.485.810', 'N02.360.810'], ['I02.399.630'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
The analgesic effect of decursinol. | Although decursinol, which is one of the coumarins purified from the dried roots of Angelica gigas Nakai, was previously demonstrated to have antinociceptive effects on various mouse pain models such as tail-flick, hot-plate, formalin, writhing, and several cytokine-induced pain tests, the possible involvement of its a... | ['Acetaminophen', 'Acetic Acid', 'Analgesics', 'Angelica', 'Animals', 'Aspirin', 'Benzopyrans', 'Butyrates', 'Disease Models, Animal', 'Drug Synergism', 'Drug Therapy, Combination', 'Male', 'Mice', 'Mice, Inbred ICR', 'Pain', 'Plant Extracts'] | 19,557,373 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D02.241.081.018.165', 'D10.251.400.045.500'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.650.940.800.575.912.250.075.088'], ['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['D03.383.663.283', 'D03.633.100.150'], ['D02.241.081.114', 'D10.251.400... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-field, variable-temperature M?ssbauer effect measurements on oxyhemeproteins. | We measured M?ssbauer spectra of human oxyhemoglobin, its isolated beta chains, and of oxymyoglobin from horse and sperm whale in fields of 4 or 6 T between 4.2 and 200 K in order to characterize the electronic state of the oxyheme complex. Diamagnetic sodium nitroprusside measured under the same conditions served as a... | ['Humans', 'Myoglobin', 'Oxyhemoglobins', 'Spectrometry, Gamma', 'Temperature'] | 6,509,067 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['D12.776.124.400.707', 'D12.776.422.316.762.687'], ['E05.196.867.776', 'E05.799.801'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Identification of the protein encoded by the transposable element Tn3 which is required for its transposition. | Protein products have now been identified which account for the entire coding capacity of the transposable element Tn3. Mutations in Tn3 have allowed us to map the genes encoding each of these peptides and to identify their role in transposition. We have found that only a single Tn3-encoded peptide is required for tran... | ['Bacterial Proteins', 'Bacteriocin Plasmids', 'DNA Transposable Elements', 'DNA, Bacterial', 'Escherichia coli', 'Genes', 'Genes, Regulator', 'Molecular Weight', 'Plasmids', 'Transcription, Genetic'] | 390,401 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Decellularized human cadaveric dermis provides a safe alternative for primary inguinal hernia repair in contaminated surgical fields. | BACKGROUND: Repair options for inguinal hernias in contaminated surgical fields include local tissue repair or mesh repair. The former is associated with higher hernia recurrence rates. The latter generally is avoided because of an unacceptably high infection rate. AlloDerm (Lifecell Corp., Branchburg, NJ) can potentia... | ['Aged', 'Aged, 80 and over', 'Collagen', 'Digestive System Surgical Procedures', 'Emergency Medical Services', 'Hernia, Femoral', 'Hernia, Inguinal', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Postoperative Complications', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Serum Albumin', 'Skin, Artifici... | 17,071,174 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E04.210'], ['N02.421.297'], ['C23.300.707.374.750'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['C23.550.767'], ['C23.550.291.937'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of microRNA-21-3p suppresses proliferation as well as invasion and induces apoptosis by targeting RNA-binding protein with multiple splicing through Smad4/extra cellular signal-regulated protein kinase signalling pathway in human colorectal cancer HCT116 cells. | MicroRNA-21-3p (miR-21-3p), the passenger strand of pre-mir-21, has been found to be high-expressing in various cancers and to be associated with tumour malignancy, which is proposed as a novel focus in malignant tumours. Colorectal cancer (CRC), currently known as one of the most prevalent malignancy, is a leading cau... | ['Apoptosis', 'Cell Movement', 'Cell Proliferation', 'Colorectal Neoplasms', 'Extracellular Signal-Regulated MAP Kinases', 'HCT116 Cells', 'Humans', 'MAP Kinase Signaling System', 'MicroRNAs', 'Neoplasm Invasiveness', 'RNA-Binding Proteins', 'Smad4 Protein'] | 29,542,167 | [['G04.146.954.035'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.16... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Urinary retention caused by female urethral diverticulum]. | We report a 49-year-old female who had circumferential urethral diverticulum. She was admitted to our department for urinary retention. A cystic lesion surrounding the urethra had been detected by magnetic resonance imaging. We diagnosed the lesion as a urethral diverticulum after injecting dye to the cystic mass from ... | ['Coloring Agents', 'Diagnostic Imaging', 'Diverticulum', 'Endoscopy', 'Female', 'Humans', 'Indigo Carmine', 'Middle Aged', 'Treatment Outcome', 'Urethral Diseases', 'Urinary Retention'] | 18,051,810 | [['D27.720.233'], ['E01.370.350'], ['C06.405.205.282.750', 'C23.300.415'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.396'], ['M01.060.116.630'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C12.777.767', 'C13.351.968.767'], ['C12.777.9... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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