Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The use of the Heimlich maneuver in near drowning: Institute of Medicine report. | The application of the Heimlich maneuver as the initial and perhaps only step for opening the airway in all near-drowning victims has been proposed by Henry Heimlich and Edward Patrick, contrary to current resuscitation guidelines for the treatment of near-drowning victims established by the Emergency Cardiac Care (ECC... | ['Airway Obstruction', 'Emergencies', 'Foreign Bodies', 'Humans', 'Near Drowning', 'Resuscitation'] | 7,673,638 | [['C08.618.846.185'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.304.500', 'N06.850.135.696.500'], ['E02.365.647']] | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Low-Cost, High-Throughput Sequencing of DNA Assemblies Using a Highly Multiplexed Nextera Process. | In recent years, next-generation sequencing (NGS) technology has greatly reduced the cost of sequencing whole genomes, whereas the cost of sequence verification of plasmids via Sanger sequencing has remained high. Consequently, industrial-scale strain engineers either limit the number of designs or take short cuts in q... | ['DNA', 'Gene Library', 'High-Throughput Nucleotide Sequencing', 'INDEL Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Single Nucleotide', 'Quality Control', 'Sequence Analysis, DNA'] | 25,913,499 | [['D13.444.308'], ['G05.360.325'], ['E05.393.760.319'], ['G05.365.590.500', 'G05.558.370'], ['E05.393.620.500'], ['G05.365.795.598'], ['J01.897.608'], ['E05.393.760.700']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Expression of secreted frizzled-related protein 4 in the primate placenta. | Secreted frizzled-related protein 4 (sFRP4) blocks the Wnt signalling pathway by competitively binding Wnt ligands (frizzled receptors). This pathway is important during development and oncogenesis. It is, however, complex with a large number of interacting proteins, isoforms and receptors. The Wnt signalling pathway h... | ['Animals', 'Apoptosis', 'Female', 'Gene Expression', 'Gestational Age', 'Humans', 'Macaca fascicularis', 'Placenta', 'Placentation', 'Pre-Eclampsia', 'Pregnancy', 'Pregnancy Trimester, First', 'Pregnancy, Animal', 'Primates', 'Proto-Oncogene Proteins', 'Term Birth', 'Trophoblasts'] | 19,146,776 | [['B01.050'], ['G04.146.954.035'], ['G05.297'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['A16.710'], ['G08.686.784.769.491'], ['C13.703.395.249'], ['G08.686.784.769'], ['G08.686.707.408'], ['G08.686.784.769.498... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Density-dependence vs. density-independence - linking reproductive allocation to population abundance and vegetation greenness. | 1. Recent studies have shown that optimal reproductive allocation depends on both climatic conditions and population density. We tested this hypothesis using six years of demographic data from eight reindeer (Rangifer tarandus) populations coupled with data on population abundance and vegetation greenness [measured usi... | ['Animals', 'Body Weight', 'Climate', 'Eating', 'Ecology', 'Female', 'Norway', 'Population Density', 'Reindeer', 'Reproduction', 'Seasons'] | 21,985,598 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G07.203.650.283', 'G10.261.330'], ['H01.158.273.248', 'H01.277.249'], ['Z01.542.816.374'], ['N01.224.600', 'N06.850.505.400.600'], ['B01.050.15... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
[Mediastinal infiltration in children with acute lymphoblastic leukemia]. | The clinical and haematological analysis is presented of six out of 68 cases of acute lymphoblastic leukaemia in children. In these six cases mediastinal involvement was found. They accounted for 8.8% of all patients and all were boys aged over 4 years. In all these cases the course was dramatic, with high risk and wit... | ['Adolescent', 'Age Factors', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Leukemia-Lymphoma, Adult T-Cell', 'Leukemic Infiltration', 'Male', 'Mediastinum', 'Prognosis', 'Sex Factors'] | 1,462,567 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.557.337.428.580.100', 'C15.604.515.560.575.100', 'C20.683.515.528.582.100'], ['C04.697.645.500', 'C23.550.727.645.500'], ['A01.923.761.800.500'], ['E01.... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of patient narratives on information search in a web-based breast cancer decision aid: an eye-tracking study. | BACKGROUND: Previous research has examined the impact of patient narratives on treatment choices, but to our knowledge, no study has examined the effect of narratives on information search. Further, no research has considered the relative impact of their format (text vs video) on health care decisions in a single study... | ['Adult', 'Aged', 'Breast Neoplasms', 'Decision Making', 'Decision Support Techniques', 'Eye Movements', 'Female', 'Humans', 'Information Seeking Behavior', 'Internet', 'Middle Aged', 'Patient Participation', 'Telemedicine', 'Video Recording'] | 24,345,424 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['F02.463.785.373'], ['E05.245', 'L01.313.500.750.190'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.372', 'F01.145.535', 'L01.143.458'], ['L01.224.230.110.500'], ['M01.060.116.630'], ['F01.100.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Hip toggle stabilization using the TightRope® system in 17 dogs: technique and long-term outcome. | OBJECTIVE: To describe the technique for, and long-term clinical outcome of, a modified hip toggle stabilization using the TightRope® system for coxofemoral luxation repair.STUDY DESIGN: Retrospective case series.METHODS: Medical records (July 2008-July 2010) including radiographs (17 limbs) of dogs that had coxofemora... | ['Animals', 'Coccyx', 'Dogs', 'External Fixators', 'Female', 'Femur', 'Gait', 'Hip Dislocation', 'Male', 'Radiography', 'Range of Motion, Articular', 'Retrospective Studies', 'Treatment Outcome'] | 24,708,485 | [['B01.050'], ['A02.835.232.834.229'], ['B01.050.150.900.649.313.750.250.216.200'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['A02.835.232.043.150'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C05.550.518.384', 'C26.289.384', 'C26.531.500'], ['E01.370.350.700'], ['E01.370.600.700', 'G11.427.760'], ['E05.3... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Simultaneous determination of four designer drugs and their major metabolites by liquid chromatography-mass spectrometry. | A sensitive liquid chromatography-electrospray ionization-ion trap mass spectrometry (LC-ESI-ITMS) method was utilized for the simultaneous analysis of four designer drugs and their in vitro metabolites in rat liver microsome S9 fraction. Four designer drugs, including methcathinone (MC), 3,4-methylenedioxymethcathinon... | ['Animals', 'Chromatography, Liquid', 'Designer Drugs', 'Humans', 'Limit of Detection', 'Linear Models', 'Male', 'Microsomes, Liver', 'Powders', 'Rats', 'Rats, Sprague-Dawley', 'Reproducibility of Results', 'Spectrometry, Mass, Electrospray Ionization', 'Substance Abuse Detection'] | 25,939,091 | [['B01.050'], ['E05.196.181.400'], ['D26.909.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Factors affecting food intake of women with Alzheimer's type dementia in long-term care. | This study assessed the nutrient intake and problems associated with the feeding of individuals who have advanced senile dementia of the Alzheimer's type (SDAT). The sample consisted of 19 non-ambulatory women, ranging in age from 67 to 105 years, with documented SDAT, who reside in a long-term-care facility. Dietary i... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Data Collection', 'Diet', 'Eating', 'Energy Intake', 'Female', 'Food, Fortified', 'Humans', 'Long-Term Care', 'Pilot Projects'] | 2,512,336 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.650.240.340'], ['G07.203.300.515', 'J02.500.515'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Oxygen vacancies versus fluorine at CeO2(111): a case of mistaken identity? | We propose a resolution to the puzzle presented by the surface defects observed with STM at the (111) surface facet of CeO 2 single crystals. In the seminal paper of Esch et al. [Science 309, 752 (2005)] they were identified with oxygen vacancies, but the observed behavior of these defects is inconsistent with the resu... | ['Cerium', 'Crystallization', 'Fluorine', 'Microscopy, Electron, Scanning Transmission', 'Models, Molecular', 'Oxygen', 'Surface Properties'] | 24,785,057 | [['D01.268.558.362.249', 'D01.552.550.399.249'], ['E05.196.300', 'G02.171'], ['D01.268.380.300'], ['E01.370.350.515.402.580.480', 'E05.595.402.580.480'], ['E05.599.595'], ['D01.268.185.550', 'D01.362.670'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of novel antibacterial peptides by chemoinformatics and machine learning. | The rise of antibiotic resistant pathogens is one of the most pressing global health issues. Discovery of new classes of antibiotics has not kept pace; new agents often suffer from cross-resistance to existing agents of similar structure. Short, cationic peptides with antimicrobial activity are essential to the host de... | ['Anti-Bacterial Agents', 'Antimicrobial Cationic Peptides', 'Artificial Intelligence', 'Drug Resistance, Multiple, Bacterial', 'Enterobacter cloacae', 'Enterococcus', 'Escherichia coli', 'Klebsiella pneumoniae', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Models, Molecular', 'Neural ... | 19,296,598 | [['D27.505.954.122.085'], ['D12.644.050', 'D12.776.543.695.054'], ['G17.035.250', 'L01.224.050.375'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['B03.440.450.425.275.200', 'B03.660.250.150.170.100'], ['B03.353.750.250.250', 'B03.510.550.250.250'], ['B03.440.450.42... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Apigenin isolated from the seeds of Perilla frutescens britton var crispa (Benth.) inhibits food intake in C57BL/6J mice. | Energy balance is monitored by the hypothalamus, which responds to peripheral signals by releasing neuropeptides that regulate energy intake and expenditure. In this study, we constructed pro-opiomelanocortin (POMC) and "cocaine and amphetamine-related transcript" (CART) promoter-driven luciferase plasmids and transfor... | ['Animals', 'Apigenin', 'Eating', 'Humans', 'Hypothalamus', 'Luciferases', 'Mice', 'Mice, Inbred C57BL', 'Nerve Tissue Proteins', 'Neuropeptides', 'Obesity', 'Perilla frutescens', 'Pro-Opiomelanocortin', 'Seeds', 'Weight Gain'] | 21,116,776 | [['B01.050'], ['D03.383.663.283.266.450.260.110', 'D03.633.100.150.266.450.260.110'], ['G07.203.650.283', 'G10.261.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D08.811.682.517', 'D12.776.532.510'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Kidneys extract BNP and NT-proBNP in healthy young men. | Renal metabolism of the cardiac marker NH2-terminal-pro-brain natriuretic peptide (NT-proBNP) has been suggested. Therefore, we determined the renal extraction ratios of NT-proBNP and its bioactive coproduct brain natriuretic peptide (BNP) at rest and during exercise. In addition, the cerebral ratios were evaluated. Te... | ['Adult', 'Blood Pressure', 'Brain', 'Exercise', 'Glomerular Filtration Rate', 'Heart Rate', 'Humans', 'Kidney', 'Male', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Protein Precursors', 'Stroke Volume'] | 16,037,399 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A08.186.211'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.390.400.300', 'G08.852.357'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['D06.472.699.584.625', 'D12.644.548.585.625', 'D12.776... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Protein-polymer conjugation via ligand affinity and photoactivation of glutathione S-transferase. | A photoactivated, site-selective conjugation of poly(ethylene glycol) (PEG) to the glutathione (GSH) binding pocket of glutathione S-transferase (GST) is described. To achieve this, a GSH analogue (GSH-BP) was designed and chemically synthesized with three functionalities: (1) the binding affinity of GSH to GST, (2) a ... | ['Animals', 'Benzophenones', 'Glutathione', 'Glutathione Transferase', 'Horses', 'Ligands', 'Light', 'Polyethylene Glycols'] | 25,315,970 | [['B01.050'], ['D02.455.426.559.389.134', 'D02.522.223'], ['D12.644.456.448'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.984.235.472'], ['D27.720.470.480'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Variants in the HEPSIN gene are associated with prostate cancer in men of European origin. | There is considerable evidence that genetic factors are involved in prostate cancer susceptibility. We have studied the association of 11 single nucleotide polymorphisms (SNPs) in the HEPSIN gene (HPN) with prostate cancer in men of European ancestry. HPN is a likely candidate in prostate cancer susceptibility, as it e... | ['Case-Control Studies', 'European Continental Ancestry Group', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Haplotypes', 'Humans', 'Male', 'Polymorphism, Single Nucleotide', 'Prostatic Neoplasms', 'Serine Endopeptidases'] | 16,783,571 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.686.508.400'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.598'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Some principles of organization of spinal neurons underlying locomotion in zebrafish and their implications. | Recent studies of the spinal motor system of zebrafish, along with work in other species, are leading to some principles that appear to underlie the organization and recruitment of motor networks in cord: (1) broad neuronal classes defined by a set of transcription factors, key morphological features, and transmitter p... | ['Animals', 'Cell Differentiation', 'Chickens', 'Electrophysiology', 'Interneurons', 'Locomotion', 'Mice', 'Motor Activity', 'Motor Neurons', 'Nerve Net', 'Neurons', 'Ranidae', 'Species Specificity', 'Spinal Cord', 'Swimming', 'Synaptic Transmission', 'Zebrafish'] | 20,536,924 | [['B01.050'], ['G04.152'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['H01.158.344.528', 'H01.158.782.236'], ['A08.675.358', 'A11.671.358'], ['G07.568.500', 'G11.427.410.568'], ['B01.050.150.900.649.313.992.635.505.500'], ['F01.145.632', 'G11.427.410.698'], ['A08.675.655.500', 'A11.671.655.500'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Control of nitrogenase reactivation by the GlnZ protein in Azospirillum brasilense. | The glnZ mutant of Azospirillum brasilense (strain 7611) showed only partial recovery (20 to 40%) after 80 min of ammonia-induced nitrogenase switch-off, whereas the wild type recovered totally within 10 min. In contrast, the two strains showed identical anoxic-induced switch-on/switch-off, indicating no cross talk bet... | ['Ammonia', 'Anaerobiosis', 'Azospirillum brasilense', 'Bacterial Proteins', 'Mutation', 'Nitrogenase', 'Time Factors'] | 11,673,445 | [['D01.362.075', 'D01.625.050'], ['G02.111.062', 'G03.078'], ['B03.440.400.425.708.100.020', 'B03.585.120', 'B03.660.050.755.750.100.020'], ['D12.776.097'], ['G05.365.590'], ['D08.811.682.647'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative Study of the Composition of Sweat from Eccrine and Apocrine Sweat Glands during Exercise and in Heat. | This preliminarily study was made to examine the differences in sweat excretions from human eccrine and apocrine sweat glands in dynamic exercise and heat conditions. Sweat samples were collected from six young males while they were either running on a treadmill or sitting in a sauna cabinet. Sweat samples of at least ... | ['Apocrine Glands', 'Eccrine Glands', 'Exercise', 'Hot Temperature', 'Humans', 'Male', 'Sweat', 'Sweat Glands', 'Sweating', 'Young Adult'] | 32,408,694 | [['A10.336.899.206', 'A17.815.830.206'], ['A10.336.899.480', 'A17.815.830.480'], ['G11.427.410.698.277', 'I03.350'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.200.849'], ... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A comparative study of the asparagine-linked oligosaccharides on siglec-5, siglec-7 and siglec-8, expressed in a CHO cell line, and their contribution to ligand recognition. | The siglecs (sialic acid-binding immunoglobulin-like lectins) mediate sialic acid-dependent cellular interactions and may in some cases signal through SH2-binding domains. In addition to the previously characterized siglecs, sialoadhesin, CD22, CD33 and myelin-associated glycoprotein, several new ones, siglec-5, siglec... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Animals', 'Antigens, CD', 'Antigens, Differentiation, B-Lymphocyte', 'Antigens, Differentiation, Myelomonocytic', 'Asparagine', 'CHO Cells', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Cell Line', 'Cricetinae', 'Erythrocytes', 'Glycosylation', 'Humans', 'Lectins'... | 11,231,274 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.051', 'D23.101.100.150'], ['D23.050.301.264.900', 'D23.101.100.900'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['A11.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Optimization of adaptive designs: efficiency evaluation. | The rising cost of clinical trials is impeding the development of new drugs. There is an acute need for critical evaluation and innovate thinking while designing the trial. Adaptive design has been repeatedly called upon in the last decade as one of the prescriptions for this intricate problem. From a pure statistical ... | ['Algorithms', 'Clinical Trials as Topic', 'Computer Simulation', 'Data Interpretation, Statistical', 'Decision Making', 'Humans', 'Models, Statistical', 'Probability', 'Research Design', 'Sample Size'] | 22,651,106 | [['G17.035', 'L01.224.050'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.50... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
The fine structure of intra-erythrocytic stages of Babesia bigemina. | The electron microscope was used to study the structure of merozoites, merozoites in the process of transformation to trophozoites, trophozoites, and the method of multiplication of B. bigemina. The merozoites were piriform in shape and surrounded by 3 peripheral membranes of which the 2 inner ones often appeared as a ... | ['Animals', 'Babesia', 'Babesiosis', 'Cattle', 'Cattle Diseases', 'Erythrocytes', 'Male', 'Microscopy, Electron'] | 614,533 | [['B01.050'], ['B01.043.075.600.580.070'], ['C01.610.701.688.122', 'C01.610.752.075', 'C01.610.752.625.122', 'C01.920.930.182', 'C22.674.710.122'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.350.515.402', 'E05.595.402']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular hydrogen messengers can lead to structural infidelity: A cautionary tale of protonated glycine. | The effects of tagging protonated glycine with either He or between 1 and 14 H2 molecules on the infrared photodissociation spectra and the ion structure were investigated. Differences in the IR spectra with either a single He atom or H2 molecule attached indicate that even a single H2 molecule can affect the frequenci... | ['Glycine', 'Helium', 'Hydrogen', 'Hydrogen Bonding', 'Mass Spectrometry', 'Protons', 'Spectrophotometry, Infrared'] | 26,374,041 | [['D12.125.481'], ['D01.268.613.350', 'D01.362.641.352'], ['D01.268.406', 'D01.362.340'], ['G02.282'], ['E05.196.566'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['E05.196.712.726.676', 'E05.196.867.826.676']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Formaldehyde assay by capacitance versus voltage and impedance measurements using bi-layer bio-recognition membrane. | A novel formaldehyde sensitive biosensor based on bacterial formaldehyde dehydrogenase (FDH) as a bio-recognition element has been developed. The bio-recognition membrane had bi-layer architecture and consisted of FDH, cross-linked with albumin, and of the cofactor NAD at a high concentration level (first layer). The s... | ['Aldehyde Oxidoreductases', 'Biosensing Techniques', 'Electric Capacitance', 'Electric Impedance', 'Electrochemistry', 'Electromagnetic Fields', 'Environmental Monitoring', 'Enzymes, Immobilized', 'Fluorocarbon Polymers', 'Formaldehyde', 'Materials Testing', 'Membranes, Artificial', 'NAD', 'Reproducibility of Results'... | 16,516,460 | [['D08.811.682.657.163'], ['E05.601.043'], ['G01.358.500.249.270'], ['G01.358.500.249.277.350'], ['H01.181.529.307'], ['G01.358.500.260', 'G01.358.750.500'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D08.811.180', 'D12.776.463.500'], ['D05.750.395', 'D25.720.395', 'J01.637.051.720.395'], ['D02.047.407'], ['E05.570'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Neural signatures of betrayal aversion: an fMRI study of trust. | Decisions are said to be 'risky' when they are made in environments with uncertainty caused by nature. By contrast, a decision is said to be 'trusting' when its outcome depends on the uncertain decisions of another person. A rapidly expanding literature reveals economically important differences between risky and trust... | ['Adolescent', 'Adult', 'Affect', 'Brain', 'Cerebral Cortex', 'Decision Making', 'Female', 'Humans', 'Interpersonal Relations', 'Magnetic Resonance Imaging', 'Male', 'Social Behavior', 'Trust', 'Uncertainty', 'Young Adult'] | 24,648,217 | [['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E01.370.350.825.500'], ['F01.145.813'], ['F01.829.401.825'], ['E05.318.740.600.900', 'F02.463.785.373.820', 'G17.680.875', 'N05.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genetic and phenotypic analysis of a large (122-member) protein S-deficient kindred provides an explanation for the familial coexistence of type I and type III plasma phenotypes. | Protein S deficiency is a known risk factor for thrombosis. The coexistence of phenotypic type I (reduction in total and free antigen) and type III (reduction in free antigen only) protein S deficiencies in 14 of 18 families was recently reported. We investigated the cause of this phenotypic variation in the largest of... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Complement Inactivator Proteins', 'Disease Susceptibility', 'Female', 'Genotype', 'Glycoproteins', 'Humans', 'Male', 'Middle Aged', 'Pedigree', 'Phenotype', 'Point Mutation', 'Protein S', 'Protein S Deficiency', 'Receptors, Complement', 'Risk Factors', 'Thrombosis'] | 9,192,759 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['D12.776.124.486.274.920'], ['C23.550.291.687', 'G07.100.250'], ['G05.380'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.393.673'], ['G05.695'], ['G05.365.590.675'], ['D12.776.124.67... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Study on the compound Fritilaria thunbergii Miq particles to the subcellular accumulation ability and inducing apoptosis of K562/A02 cells]. | OBJECTIVE: To investigate the effects of the Compound Fritillaria thunbergii Miq Particles (CFMP) to the sub-cellular accumulation ability and inducing the apoptosis of K562/A02 cells, explore the mechanism of the CFMP reserve the multi-drug resistance of K562/A02 cells.METHODS: Forty Wistar male rats were divided into... | ['Animals', 'Apoptosis', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Drugs, Chinese Herbal', 'Flow Cytometry', 'Fritillaria', 'Humans', 'K562 Cells', 'Male', 'Rats'] | 20,462,045 | [['B01.050'], ['G04.146.954.035'], ['G07.690.773.984.300'], ['G07.690.773.984.395'], ['D20.215.784.500.350', 'D26.335'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.650.940.800.575.912.25... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute facial palsy in children--a 2-year follow-up study with focus on Lyme neuroborreliosis. | OBJECTIVE: Acute facial palsy in children is believed to be a rather benign neurological condition. Follow-up-studies are sparse, especially including a thorough otoneurological re-examination. The aim of this study was to examine children with a history of facial palsy in order to register the incidence of complete re... | ['Adolescent', 'Borrelia', 'Child', 'Child, Preschool', 'Facial Nerve', 'Facial Paralysis', 'Female', 'Follow-Up Studies', 'Humans', 'Lyme Neuroborreliosis', 'Male', 'Outcome Assessment, Health Care', 'Recovery of Function', 'Retrospective Studies', 'Severity of Illness Index', 'Time Factors'] | 12,745,151 | [['M01.060.057'], ['B03.440.425.410.711.193', 'B03.851.595.193'], ['M01.060.406'], ['M01.060.406.448'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['C07.465.327', 'C10.597.622.214', 'C23.888.592.636.214'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Patterns of CT use in Japan, 2014: A nationwide cross-sectional study. | OBJECTIVES: To describe CT usage in Japan by age, gender, and region and to clarify the relationship between aging and CT examination rate.MATERIALS AND METHODS: We conducted a cross-sectional study using openly accessible data from the National Database, which includes all Japanese health insurance claim data from 201... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Databases, Factual', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Japan', 'Male', 'Middle Aged', 'Physical Examination', 'Sex Distribution', 'Tomography, X-Ray Computed', 'Young Adult'] | 29,153,375 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.9... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Intrinsic disorder is a common structural characteristic of RxLR effectors in oomycete pathogens. | Intrinsic disorder is common in nature and has been studied to play important biological roles in bacterial effectors. However, disorder in oomycete RxLR effectors has not been investigated previously and the roles are unknown. Our results of PONDR VL-XT disorder analysis showed that predicted oomycete RxLR effectors w... | ['Amino Acid Sequence', 'Computational Biology', 'Fungal Proteins', 'Oomycetes', 'Protein Conformation', 'Virulence Factors'] | 29,029,698 | [['G02.111.570.060', 'L01.453.245.667.060'], ['H01.158.273.180', 'L01.313.124'], ['D12.776.354'], ['B01.750.580'], ['G02.111.570.820.709'], ['D23.946.896']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Altered gaze following during live interaction in infants at risk for autism: an eye tracking study. | BACKGROUND: The ability to follow gaze is an important prerequisite for joint attention, which is often compromised in children with autism spectrum disorder (ASD). The direction of both the head and eyes provides cues to other people's attention direction, but previous studies have not separated these factors and thei... | ['Attention', 'Autism Spectrum Disorder', 'Cues', 'Early Diagnosis', 'Eye Movements', 'Family Health', 'Female', 'Fixation, Ocular', 'Head Movements', 'Humans', 'Imitative Behavior', 'Infant', 'Male', 'Pursuit, Smooth', 'Risk', 'Single-Blind Method', 'Social Behavior', 'Social Perception'] | 26,819,699 | [['F02.830.104.214'], ['F03.625.164.113'], ['F02.463.425.234'], ['E01.390'], ['G11.427.410.140', 'G14.350'], ['N01.400.300'], ['G14.350.253'], ['G11.427.410.478'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.510'], ['M01.060.703'], ['G14.350.453'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Central cyanosis on a psychiatric unit treated at the Salford Royal Hospital. | We describe a case of acquired methaemoglobinaemia due to frequent use of the 'legal high' known as 'Pink Panthers'. This contains 5,6-Methylenedioxy-2-aminoindane and 2-Aminoindane, both amphetamine analogues with the potential to cause methaemoglobinaemia. Furthermore, the most common 'cutting agent' for legal highs ... | ['Benzocaine', 'Cyanosis', 'Humans', 'Illicit Drugs', 'Indans', 'Methemoglobinemia', 'Schizophrenic Psychology', 'Substance-Related Disorders'] | 25,063,354 | [['D02.241.223.100.050.500.643', 'D02.455.426.559.389.127.020.937.687'], ['C23.888.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['D02.455.426.559.847.486.487', 'D04.615.486.487'], ['C15.378.619'], ['F04.824'], ['C25.775', 'F03.900']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endotracheal reintubation: a closer look at a preventable condition. | We designed a prospective study of endotracheal intubations and reintubations in our inner city Level 1 Trauma Center, to determine the frequency and causes of reintubation and evaluate the impact of an educational intervention aimed at minimizing unplanned extubations (UEs). After an initial 3-month phase, efforts wer... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Clinical Nursing Research', 'Critical Care', 'Equipment Failure', 'Female', 'Humans', 'Intubation, Intratracheal', 'Male', 'Middle Aged', 'Prospective Studies'] | 9,274,152 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['H01.770.644.145.390.234', 'H02.478.395.234', 'N04.590.233.508.613.234'], ['E02.760.190', 'N02.421.585.190'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['M01.060.116.630']... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Genetic background affects stability of mecA in Staphylococcus aureus. | The staphylococcal methicillin resistance determinant, mecA, resides on a mobile genetic element, staphylococcus chromosomal cassette mec (SCCmec). The distribution of SCCmec in nature is limited to relatively few clonal complexes of related methicillin-resistant Staphylococcus aureus (MRSA). We have previously reporte... | ['Bacterial Proteins', 'Base Sequence', 'DNA Primers', 'Drug Resistance, Microbial', 'Methicillin Resistance', 'Penicillin-Binding Proteins', 'Plasmids', 'Staphylococcus aureus', 'Tetracycline', 'Transformation, Bacterial', 'beta-Lactamases'] | 15,872,270 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G06.225', 'G07.690.773.984.269'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], ['D08.811.710', 'D12.776.097.545'], ['G05.360.600'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Estradiol modulates Kiss1 neuronal response to ghrelin. | Ghrelin is a metabolic signal regulating energy homeostasis. Circulating ghrelin levels rise during starvation and fall after a meal, and therefore, ghrelin may function as a signal of negative energy balance. Ghrelin may also act as a modulator of reproductive physiology, as acute ghrelin administration suppresses gon... | ['Acylation', 'Animals', 'Arcuate Nucleus of Hypothalamus', 'Estradiol', 'Estrogen Receptor alpha', 'Estrogen Replacement Therapy', 'Female', 'Gene Expression Regulation', 'Ghrelin', 'Green Fluorescent Proteins', 'Hypothalamus', 'Kisspeptins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Nerve Tissue Proteins', '... | 24,473,434 | [['G02.111.012', 'G02.607.063', 'G03.040'], ['B01.050'], ['A08.186.211.180.497.352.081', 'A08.186.211.200.317.357.352.081'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D12.776.826.750.350.174'], ['E02.319.452.150'], ['G05.308'], ['D06.472.699.301', 'D12.644.548.322'], ['D12.776.532.265'], ['A08.186.211.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Voice assessment and demographic data of applicants for a school of speech therapists]. | BACKGROUND: Demographic data, subjective und objective voice analysis as well as self-assessment of voice quality from applicants for a school of speech therapists were investigated.METHODS: Demographic data from 116 applicants were collected and their voice quality assessed by three independent judges. An objective ev... | ['Adolescent', 'Adult', 'Career Choice', 'Female', 'Humans', 'Male', 'Middle Aged', 'Music', 'Personnel Selection', 'School Admission Criteria', 'Self-Assessment', 'Sound Spectrography', 'Speech Therapy', 'Voice Quality'] | 18,247,263 | [['M01.060.057'], ['M01.060.116'], ['F02.463.785.373.346.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['K01.602'], ['N04.452.677.500'], ['I02.399.750'], ['F01.752.747.792.537'], ['E05.855'], ['E02.760.169.063.500.727.552', 'E02.831.727.552'], ['G09.772.925.960']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
High-frequency ultrasound for monitoring changes in liver tissue during preservation. | Currently the only method to assess liver preservation injury is based on liver appearance and donor medical history. Previous work has shown that high-frequency ultrasound could detect ischemic cell death due to changes in cell morphology. In this study, we use high-frequency ultrasound integrated backscatter to asses... | ['Animals', 'Image Interpretation, Computer-Assisted', 'Ischemia', 'Liver', 'Organ Preservation', 'Rats', 'Rats, Wistar', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Severity of Illness Index', 'Ultrasonography'] | 15,742,939 | [['B01.050'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['C23.550.513'], ['A03.620'], ['E02.792.833.660', 'E05.760.833.660'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Topical silymarin versus hydroquinone in the treatment of melasma: A comparative study. | BACKGROUND: Melasma is a highly prevalent hyperpigmentation disorder with a high relapsing rate and a negative impact on the psychological state of the affected patients. The exact pathogenesis of melasma is not completely elucidated; however, ultraviolet induced oxidative stress has an important role in its pathogenes... | ['Administration, Cutaneous', 'Adult', 'Antioxidants', 'Female', 'Humans', 'Hydroquinones', 'Melanosis', 'Middle Aged', 'Patient Satisfaction', 'Severity of Illness Index', 'Silymarin', 'Treatment Outcome'] | 30,146,802 | [['E02.319.267.120.060'], ['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.657.393'], ['C17.800.621.430.530'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cromolyn sodium in the treatment of asthma: coming of age in the United States. | Cromolyn sodium has matured as a first-line drug in the management of asthma in the United States. New pharmacokinetic assays reveal that it exerts classic dose-response effects both in vitro and in vivo. The protective effect of cromolyn sodium is due chiefly to its ability to inhibit mediator release from mast cells,... | ['Aerosols', 'Asthma', 'Biological Availability', 'Bronchi', 'Bronchial Provocation Tests', 'Bronchial Spasm', 'Cromolyn Sodium', 'Dose-Response Relationship, Drug', 'Humans', 'Inflammation', 'Mast Cells', 'Metabolic Clearance Rate', 'Theophylline'] | 3,926,853 | [['D20.280.055', 'D26.255.165.055'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['G03.787.151', 'G07.690.725.129'], ['A04.411.125'], ['E01.370.386.700.125'], ['C08.127.321'], ['D03.383.663.283.266.300', 'D03.633.100.150.266.300'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-density neutrophils in MGUS and multiple myeloma are dysfunctional and immune-suppressive due to increased STAT3 downstream signaling. | To understand neutrophil impairment in the progression from MGUS through active MM, we investigated the function of mature, high-density neutrophils (HDNs), isolated from peripheral blood. In 7 MM, 3 MGUS and 3 healthy subjects by gene expression profile, we identified a total of 551 upregulated and 343 downregulated g... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Case-Control Studies', 'Disease Progression', 'Disease Susceptibility', 'Female', 'Follow-Up Studies', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Monoclonal Gammopathy of Un... | 32,029,833 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.656'], ['C23.550.291.687', 'G07.100.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.393.33... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Trapping and stabilization of integral membrane proteins by hydrophobically grafted glucose-based telomers. | Amphipols (APols) are short amphipathic polymers designed to adsorb onto the transmembrane surface of membrane proteins, keeping them water-soluble in the absence of detergent. Current APols carry charged groups, which is a limitation for certain types of applications. This has prompted the development of totally nonio... | ['Bacterial Outer Membrane Proteins', 'Bacteriorhodopsins', 'Glucose', 'Glycosylation', 'Hydrophobic and Hydrophilic Interactions', 'Immobilized Proteins', 'Membrane Proteins', 'Polymers', 'Solubility', 'Water'] | 20,000,638 | [['D12.776.097.120', 'D12.776.543.100'], ['D12.776.090.200', 'D12.776.157.530.450.250.875.249', 'D12.776.543.585.450.250.875.249', 'D12.776.752.812.249'], ['D09.947.875.359.448'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['G02.409'], ['D12.776.463'], ['D12.776.543'], ['D05.750', 'D25.720', 'J01.637.051.720'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Risk of second primary cancer in patients treated with radiotherapy for rectal cancer. | BACKGROUND: Many patients with rectal cancer receive radiotherapy (RT) to reduce the risk of local recurrence. Radiation may give rise to adverse effects, including second primary cancers. In view of the divergent results of previous studies, the present study evaluated the risk of second primary cancer following RT in... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Neoplasms, Second Primary', 'Proportional Hazards Models', 'Radiotherapy, Adjuvant', 'Randomized Controlled Trials as Topic', 'Rectal Neoplasms', 'Registries', 'Risk ... | 27,802,358 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.682', 'C26.733.476', 'G01.750.748.500.476'], ['C04.692'], ['E05.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Enhanced proliferation, growth factor induction and immortalization by adenovirus E1A 12S in the absence of E1B. | Immortalization and transformation of primary epithelial cells requires expression of the adenovirus E1A and E1B genes, respectively. The E1A gene is involved in growth stimulatory processes. Little is known about the mechanism utilized by E1B, however, roles in growth stimulatory processes have also been implied. To d... | ['Adenovirus E1A Proteins', 'Adenovirus E1B Proteins', 'Animals', 'Cell Division', 'Cell Transformation, Viral', 'Cells, Cultured', 'DNA', 'Genes, p53', 'Growth Substances', 'Rats', 'Rats, Inbred F344'] | 8,058,328 | [['D12.776.460.050.100', 'D12.776.624.664.520.045.050.100', 'D12.776.930.100', 'D12.776.964.700.045.050.100', 'D23.050.285.062.045', 'D23.050.327.062.045'], ['D12.776.460.050.110', 'D12.776.624.664.520.045.050.110', 'D12.776.930.110', 'D12.776.964.700.045.050.110', 'D23.050.285.062.050', 'D23.050.327.062.050'], ['B01.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulatory effects of alpha-linolenic acid on generation of reactive oxygen species in elaidic acid enriched peritoneal macrophages in rats. | Fatty acids are known to influence the ability of macrophages to generate reactive oxygen species (ROS). However the effect of elaidic acid (EA, 18:1 trans fatty acid) on ROS generation is not well studied. Rat peritoneal macrophages were enriched with elaidic acid by incubating the cells with 80 1M EA. The macrophages... | ['Animals', 'Cells, Cultured', 'Fatty Acids', 'Linseed Oil', 'Macrophages, Peritoneal', 'Male', 'Oleic Acid', 'Oleic Acids', 'Rats', 'Rats, Wistar', 'Reactive Oxygen Species', 'alpha-Linolenic Acid'] | 25,241,585 | [['B01.050'], ['A11.251'], ['D10.251'], ['D10.212.507.550', 'D10.627.700.615', 'D20.215.784.750.615'], ['A11.329.372.630', 'A11.627.482.630', 'A11.733.397.630', 'A15.382.670.522.630', 'A15.382.680.397.630'], ['D10.251.355.325.600.525'], ['D10.251.355.325.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Migration of metal-on-metal versus ceramic-on-polyethylene hip prostheses. | In a prospective randomized study, 32 metal-on-metal prostheses and 29 ceramic-on-polyethylene prostheses of similar design were implanted in 59 patients. Radiolucency, cup migration, wear, and function were examined after a minimum of 2 years followup (followup rate, 87%). The purpose of the current study was to evalu... | ['Aged', 'Ceramics', 'Equipment Failure Analysis', 'Female', 'Follow-Up Studies', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Male', 'Metals', 'Middle Aged', 'Polyethylene', 'Prospective Studies', 'Prosthesis Design', 'Prosthesis Failure', 'Radiography', 'Range of Motion, Articular'] | 12,838,059 | [['M01.060.116.100'], ['J01.637.153'], ['E05.325.192'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.552'], ['M01.060.116.630'], ['D02.455.326.271.665.550.500', 'D05.750.716.507... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Improved sensitivity of DNA microarrays using photonic crystal enhanced fluorescence. | DNA microarrays are used to profile changes in gene expression between samples in a high-throughput manner, but measurements of genes with low expression levels can be problematic with standard microarray substrates. In this work, we expand the detection capabilities of a standard microarray experiment using a photonic... | ['Crystallization', 'DNA', 'Oligonucleotide Array Sequence Analysis', 'Photons', 'Spectrometry, Fluorescence'] | 20,704,375 | [['E05.196.300', 'G02.171'], ['D13.444.308'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['E05.196.712.516.600.676', 'E05.196.867.726']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of utterance length upon bilabial closure duration of selected deaf children. | Measurements were made of intraoral air pressure associated with bilabial closure durations of VCV syllables in sentence-like frames of increasing length for nine deaf and nine matched normal hearing chidren. Results demonstrated significantly longer absolute closure durations at all utterance lengths for the deaf, but... | ['Articulation Disorders', 'Child', 'Deafness', 'Female', 'Humans', 'Lip', 'Male', 'Phonation'] | 7,419,730 | [['C10.597.606.150.500.800.150', 'C23.888.592.604.150.500.800.150'], ['M01.060.406'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.456.505.631.515', 'A14.549.336'], ['G09.772.585']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A wide variety of Clostridium perfringens type A food-borne isolates that carry a chromosomal cpe gene belong to one multilocus sequence typing cluster. | Of 98 suspected food-borne Clostridium perfringens isolates obtained from a nationwide survey by the Food and Consumer Product Safety Authority in The Netherlands, 59 strains were identified as C. perfringens type A. Using PCR-based techniques, the cpe gene encoding enterotoxin was detected in eight isolates, showing a... | ['Chromosomes, Bacterial', 'Clostridium perfringens', 'Cluster Analysis', 'DNA Fingerprinting', 'DNA, Bacterial', 'Enterotoxins', 'Food Microbiology', 'Genotype', 'Molecular Sequence Data', 'Multilocus Sequence Typing', 'Netherlands', 'Plasmids'] | 22,865,060 | [['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['D13.444.308.212'], ['D23.9... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture ... | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Serum androgens and estrogens in postmenopausal women with and without endometrial cancer. | Thirty-five consecutive patients with adenocarcinoma of the endometrium and an equal number of control subjects matched to the cancer patients for age and percentage of ideal weight were studied prospectively. In the cancer patients, the mean +/- SE serum androstenedione, testosterone, estrone (E1) and estradiol (E2) l... | ['Adenocarcinoma', 'Age Factors', 'Aged', 'Androgens', 'Diabetes Complications', 'Estradiol', 'Estrogens', 'Estrone', 'Female', 'Humans', 'Middle Aged', 'Obesity', 'Prospective Studies', 'Risk', 'Uterine Neoplasms'] | 7,361,834 | [['C04.557.470.200.025'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D27.505.696.399.472.161'], ['C19.246.099'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D27.505.696.399.472.277'], ['D04.210.500.365.415.414', 'D04.210.500.578.502.497', 'D06.472.040.502.497', 'D06.472.334.851.437.996... | ['Diseases [C]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nitric oxide synthase type II expression by different cell types in MHV-JHM encephalitis suggests distinct roles for nitric oxide in acute versus persistent virus infection. | Intranasal inoculation with mouse hepatitis virus strain JHM (MHV-JHM) results in acute meningoencephalitis. We found NOS II mRNA expression in brains of acutely infected animals on days 5 through 7 after infection. In situ hybridization and immunohistochemistry demonstrated NOS II message and protein in infiltrating m... | ['Acute Disease', 'Animals', 'Central Nervous System', 'Chronic Disease', 'Coronavirus Infections', 'Encephalomyelitis', 'In Situ Hybridization', 'Isoenzymes', 'Mice', 'Mice, Inbred C57BL', 'Murine hepatitis virus', 'Nitric Oxide', 'Nitric Oxide Synthase', 'RNA, Messenger', 'Tissue Distribution'] | 9,058,755 | [['C23.550.291.125'], ['B01.050'], ['A08.186'], ['C23.550.291.500'], ['C01.925.782.600.550.200'], ['C01.207.291', 'C10.228.228.291', 'C10.228.440'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['D08.811.348', 'D12.776.800.300']... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Correlations of the indicators of biochemical composition and physico-chemical properties of the bile in chronic cholecystitis]. | The study of the factors relevant to the bile colloid stability in aggravation of calculous or ++non-calculous cholecystitis demonstrated changes in aggregative-kinetic stability of bile presenting with low boundary of the phase transition, electrokinetic potential, mass and growing size of macromolecular compounds. Th... | ['Bile', 'Cholecystitis', 'Cholelithiasis', 'Chronic Disease', 'Humans', 'Molecular Weight', 'Proteins', 'Risk Factors', 'Trace Elements', 'Viscosity'] | 2,625,961 | [['A12.200.087'], ['C06.130.564.263'], ['C06.130.409'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.494'], ['D12.776'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['D01.268.811', 'D27.505.696.49... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Lower birth weight and attenuated adrenocortical response to ACTH in offspring from sows that orally received cortisol during gestation. | Prenatal stress is known to affect several offspring characteristics, but its effects depend among other factors on the period of gestation in which it is applied. In the present study, oral administration of hydrocortisone-acetate (HCA) was used to elevate cortisol concentrations in pregnant sows to levels also observ... | ['Adrenocorticotropic Hormone', 'Animals', 'Animals, Newborn', 'Birth Weight', 'Body Composition', 'Body Weight', 'Female', 'Hydrocortisone', 'Least-Squares Analysis', 'Litter Size', 'Pregnancy', 'Pregnancy Complications', 'Random Allocation', 'Saliva', 'Stress, Physiological', 'Swine'] | 16,107,308 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['B01.050.050.282'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Optimization of physical and mechanical properties for chitosan-nanocellulose biocomposites. | Chitosan (CHT) is a biodegradable compound and has excellent performance in forming films; on the other hand, nanocellulose (NCL) crystals have low densities and are less expensive than other nanofillers. A novel and simple method was applied to develop CHT-NCL nanocomposite (NCP) from CHT powder of high molecular weig... | ['Cellulose', 'Chitosan', 'Elastic Modulus', 'Glycerol', 'Nanostructures', 'Permeability', 'Steam', 'Tensile Strength'] | 24,708,973 | [['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D05.750.078.139.500', 'D09.698.211.500'], ['G01.374.590.605'], ['D02.033.800.875.500', 'D09.853.875.500'], ['J01.637.512'], ['G02.723'], ['D01.045.250.875.800', 'D01.248.497.158.459.650.800', 'D01.650.550.925.800', 'G16.500.887... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
(1-->3)-beta-D-glucan in culture fluid of fungi activates factor G, a limulus coagulation factor. | Two well-known polysaccharides, (1-->3)-beta-D-glucan and mannan, are major structural components of the fungus cell wall. The G test is a direct method to measure (1-->3)-beta-D-glucan using a (1-->3)-beta-D-glucan-sensitive component, factor G, fractionated from the limulus lysate. The concentration of (1-->3)-beta-D... | ['Agglutination', 'Animals', 'Antineoplastic Agents', 'Aspergillus fumigatus', 'Candida albicans', 'Cryptococcus neoformans', 'Culture Media', 'Glucan Endo-1,3-beta-D-Glucosidase', 'Glucans', 'Horseshoe Crabs', 'Limulus Test', 'Mannans', 'beta-Glucans'] | 8,531,015 | [['G02.111.026', 'G12.122.100'], ['B01.050'], ['D27.505.954.248'], ['B01.300.381.081.295'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['D27.720.470.305', 'E07.206'], ['D08.811.277.450.420.200.600'], ['D05.750.078.562', 'D09.698.365'], ['B0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The medaka mutation tintachina sheds light on the evolution of V-ATPase B subunits in vertebrates. | Vacuolar-type H(+) ATPases (V-ATPases) are multimeric protein complexes that play a universal role in the acidification of intracellular compartments in eukaryotic cells. We have isolated the recessive medaka mutation tintachina (tch), which carries an inactivating modification of the conserved glycine residue (G75R) o... | ['Animals', 'Biological Evolution', 'Molecular Sequence Data', 'Mutation', 'Oryzias', 'Phenotype', 'Protein Subunits', 'Vacuolar Proton-Translocating ATPases', 'Vertebrates'] | 24,225,653 | [['B01.050'], ['G05.045', 'G16.075'], ['L01.453.245.667'], ['G05.365.590'], ['B01.050.150.900.493.850.139.650'], ['G05.695'], ['D12.776.813'], ['D08.811.277.040.025.325.875', 'D08.811.913.696.650.150.500.875', 'D12.776.157.530.450.250.875.500.875', 'D12.776.543.585.450.250.875.500.875'], ['B01.050.150.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A Randomized Controlled Trial of Allopurinol in Patients With Peripheral Arterial Disease. | BACKGROUND: Patients with peripheral arterial disease (PAD) are limited by intermittent claudication in the distance they can walk. Allopurinol has been shown in coronary arterial disease to prolong exercise before angina occurs, likely by prevention of oxygen wastage in tissues and reduction of harmful oxidative stres... | ['Adult', 'Aged', 'Aged, 80 and over', 'Allopurinol', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Exercise Test', 'Exercise Tolerance', 'Female', 'Follow-Up Studies', 'Free Radical Scavengers', 'Humans', 'Intermittent Claudication', 'Male', 'Middle Aged', 'Peripheral Arterial Disease', 'Retrospective St... | 26,277,090 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D03.633.100.759.160'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['G11.427.680.270'], ['E05.318.372.500.750... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The effect of non-steroidal anti-inflammatory drugs on phytohaemagglutinin stimulated lymphocytes: relevance to possible therapeutic immunosuppression by fenclofenac. | Representatives of seven chemical groups of non-steroidal anti-inflammatory drugs were tested for their effect on activation and replicative growth of phytohaemagglutinin stimulated normal human lymphocytes in vitro at concentrations in the high therapeutic range, and, where possible, at 10 times that concentration. Fe... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Cell Survival', 'DNA', 'Flow Cytometry', 'Humans', 'Immunosuppressive Agents', 'Lymphocyte Activation', 'Lymphocytes', 'Phenylacetates', 'Phytohemagglutinins', 'RNA'] | 2,460,411 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G04.346'], ['D13.444.308'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Irreversible oxidation of ferricytochrome c by lignin peroxidase. | Lignin peroxidase (LiP) from Phanerochaete chrysosporium catalyzes irreversible oxidative damage to ferricytochrome c (Cc3+) in the presence of H2O2 and 3,4-dimethoxybenzyl (veratryl) alcohol (VA). Atomic absorption analysis and UV/vis spectroscopy indicate that the oxidation of Cc3+ is accompanied by a loss of heme ir... | ['Basidiomycota', 'Benzyl Alcohols', 'Chromatography, High Pressure Liquid', 'Cytochrome c Group', 'Dimerization', 'Oxidation-Reduction', 'Peroxidases'] | 9,485,329 | [['B01.300.179'], ['D02.033.160', 'D02.455.426.559.389.140.200'], ['E05.196.181.400.300'], ['D08.244.286', 'D12.776.422.220.286'], ['G02.206', 'G03.230'], ['G02.700', 'G03.295.531'], ['D08.811.682.732']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of Geriatric Assessment Tools in Selecting Therapies in Women Aged ?70 Years With Hormone Receptor-Positive Early-Stage Breast Cancer: Preliminary Experience With a Quality Improvement Initiative. | PURPOSE: To develop a multidisciplinary algorithmic approach to management of women aged ?70 years with clinically staged T1N0 hormone receptor-positive breast cancer, including geriatric assessments predicting life expectancy and the likelihood of functional decline in the near future, in the context of a program-wide... | ['Aged', 'Aged, 80 and over', 'Algorithms', 'Breast Neoplasms', 'Dose Fractionation, Radiation', 'Female', 'Geriatric Assessment', 'Humans', 'Life Expectancy', 'Practice Guidelines as Topic', 'Prognosis', 'Quality Improvement', 'Radiotherapy, Adjuvant', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Sentinel Lymph ... | 28,366,577 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['C04.588.180', 'C17.800.090.500'], ['E02.815.639.200'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemica... | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
A Type-2 Fuzzy Image Processing Expert System for Diagnosing Brain Tumors. | The focus of this paper is diagnosing and differentiating Astrocytomas in MRI scans by developing an interval Type-2 fuzzy automated tumor detection system. This system consists of three modules: working memory, knowledge base, and inference engine. An image processing method with three steps of preprocessing, segmenta... | ['Algorithms', 'Astrocytoma', 'Brain Neoplasms', 'Expert Systems', 'Fuzzy Logic', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging'] | 26,276,018 | [['G17.035', 'L01.224.050'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['L01.224.050.375.190'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Unique expression, processing regulation, and regulatory network of peach (Prunus persica) miRNAs. | BACKGROUND: MicroRNAs (miRNAs) have recently emerged as important gene regulators in plants. MiRNAs and their targets have been extensively studied in Arabidopsis and rice. However, relatively little is known about the characterization of miRNAs and their target genes in peach (Prunus persica), which is a complex crop ... | ['Base Sequence', 'Conserved Sequence', 'Gene Expression Regulation, Plant', 'Gene Regulatory Networks', 'MicroRNAs', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Organ Specificity', 'Plant Proteins', 'Prunus', 'RNA Processing, Post-Transcriptional', 'RNA, Small Interfering', 'Species Specificity', 'Transcr... | 22,909,020 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580'], ['G05.308.375'], ['G05.360.080.689.360'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['G07.650'], ['D12.776.765'], ['B01.650.940.800.575.912.250.859.9... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Minimal oxidation and inflammogenicity of pristine graphene with residence in the lung. | Two-dimensional graphitic carbon, graphene, is a new form of nanomaterial with great potential in a wide variety of applications. It is therefore crucial to investigate the behaviour of graphene in biological systems to assess potential adverse effects that might follow from inhalation exposure. In this study we focuss... | ['Animals', 'Female', 'Graphite', 'Horseradish Peroxidase', 'Inhalation Exposure', 'Lung', 'Mice', 'Mice, Inbred C57BL', 'Oxidation-Reduction', 'Pneumonia', 'Spectrum Analysis, Raman'] | 23,924,429 | [['B01.050'], ['D01.268.150.300', 'D01.578.300'], ['D08.811.682.732.512'], ['N06.850.460.350.112'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['G02.700', 'G03.295.531'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Noninfectious inflammation after intravitreal injection of aflibercept: clinical characteristics and visual outcomes. | PURPOSE: To report the presenting features and clinical outcomes of a series of patients with noninfectious inflammation after intravitreal aflibercept injection.DESIGN: Noncomparative consecutive case series.METHODS: Medical records of patients who presented with noninfectious inflammation after intravitreal afliberce... | ['Aged', 'Aged, 80 and over', 'Angiogenesis Inhibitors', 'Endophthalmitis', 'Female', 'Glucocorticoids', 'Humans', 'Intravitreal Injections', 'Male', 'Receptors, Vascular Endothelial Growth Factor', 'Recombinant Fusion Proteins', 'Retinal Vein Occlusion', 'Retrospective Studies', 'Visual Acuity', 'Wet Macular Degenerat... | 24,983,791 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['C01.375.265', 'C11.294.265'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.475.500'], ['D08.811.913.696.620.682.725.400.95... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Are preterm-born survivors at risk of long-term respiratory disease? | BACKGROUND: To evaluate the long-term impact of preterm birth on respiratory function in female patients born preterm, we undertook spirometric examinations twice, as they reached the age of puberty, then follow-up examinations of part of the same cohort in adulthood. We sought evidence that preterm birth is correlated... | ['Adolescent', 'Age Factors', 'Child', 'Female', 'Follow-Up Studies', 'Forced Expiratory Volume', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Lung', 'Lung Diseases', 'Maximal Midexpiratory Flow Rate', 'Premature Birth', 'Puberty', 'Risk Factors', 'Spirometry', 'Time Factors', 'Vital Capacity'] | 28,614,994 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis in patients with colorectal cancer. | Long noncoding RNAs (lncRNA) are emerging as key molecules in human cancer. Prostate cancer-associated ncRNA transcripts 1 (PCAT-1), a lncRNA, has been recently revealed involving in human prostate cancer progression. However, whether PCAT-1 could serve as novel biomarker to predict prognosis in colorectal cancer (CRC)... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Case-Control Studies', 'Colorectal Neoplasms', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Prognosis', 'RNA, Long Noncoding', 'RNA, Messenger', 'Risk Factors'] | 23,640,607 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.90... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cefamandole in the treatment of infections due to Enterobacter and indole-positive Proteus. | Clinical and bacteriologic results are reported for 80 patients treated with 1.5--12 g of cefamandole daily for a variety of infections caused by Enterobacter and indole-positive Proteus, organisms that have been resistant to most available cephalosporins. Of 45 patients with infections due to Enterobacter, 41 (91%) ha... | ['Adult', 'Aged', 'Cefamandole', 'Cephalosporins', 'Enterobacter', 'Enterobacteriaceae Infections', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Proteus Infections', 'Pyelonephritis', 'Skin Ulcer', 'Surgical Wound Infection', 'Urinary Tract Infections'] | 649,997 | [['M01.060.116'], ['M01.060.116.100'], ['D02.065.589.099.249.150', 'D02.886.665.074.150', 'D03.633.100.300.249.150'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['B03.440.450.425.275', 'B03.660.250.150.170'], ['C01.150.252.400.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibitory effects of ketamine on the isolated uteri of the rat: evidence for the mechanism of action. | The inhibitory effect of ketamine on the agonist-induced contraction of isolated rat uteri was compared with that of papaverine and verapamil. Under similar experimental conditions papaverine and verapamil were found to be more potent than ketamine. When preparations were preincubated for 20 min with either ketamine (3... | ['Animals', 'Barium', 'Barium Compounds', 'Chlorides', 'Female', 'In Vitro Techniques', 'Ketamine', 'Oxytocin', 'Papaverine', 'Potassium', 'Rats', 'Rats, Inbred Strains', 'Uterine Contraction', 'Uterus', 'Verapamil'] | 6,661,686 | [['B01.050'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['D01.103'], ['D01.210.450.150', 'D01.248.497.158.215'], ['E05.481'], ['D02.455.426.392.368.367.652'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['D03.132.098.666', 'D03.132.577.750', 'D03.633.100.531.085.666'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myocardial Ischemia caused by a coronary anomaly: left circumflex coronary artery arising from right sinus of valsalva. | We present the case of a patient in whom a previously undetected anomalous origin of the circumflex coronary artery caused myocardial ischemia and led to positive myocardial scintigraphic results. Subsequent coronary angiography showed that the left circumflex coronary artery arose from the right coronary ostium-an ano... | ['Aged', 'Coronary Angiography', 'Coronary Vessel Anomalies', 'Dyspnea', 'Humans', 'Male', 'Myocardial Ischemia'] | 15,562,848 | [['M01.060.116.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.240.400.210', 'C14.280.400.210', 'C16.131.240.400.210'], ['C08.618.326', 'C23.888.852.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647', 'C14.907.585']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chronic effects of angiotensin-converting enzyme inhibition on kinin receptor binding sites in the rat spinal cord. | With the use of in vitro receptor autoradiography, this study aims at determining whether the higher level of kinin B(2) receptor density in the spinal cord of the spontaneously hypertensive rat (SHR) is secondary to arterial hypertension and whether chronic treatment with angiotensin I-converting enzyme inhibitors (AC... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Antihypertensive Agents', 'Autoradiography', 'Blood Pressure', 'Body Weight', 'Bradykinin Receptor Antagonists', 'Hypertension', 'Losartan', 'Male', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Receptor, Bradykinin B1', 'Receptor, Bradykinin B2', 'Receptors, ... | 12,586,640 | [['D27.505.519.389.745.085'], ['B01.050'], ['D27.505.954.411.162'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D27.505.519.265'], ['C14.907.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytokines in gingival crevicular fluid of adolescents and young adults. | BACKGROUND/AIM: The purpose of this study was to compare the levels of the cytokines interleukin-1beta (IL-1beta), IL-4, and IL-8 in the gingival crevicular fluid (GCF) of adolescents and young adults.METHODS: Twenty-five adolescents aged between 14 and 16 years (Group A) and 20 periodontally healthy young adults aged ... | ['Adolescent', 'Adult', 'Age Factors', 'Case-Control Studies', 'Cross-Sectional Studies', 'Dental Plaque', 'Female', 'Gingival Crevicular Fluid', 'Humans', 'Interleukin-1beta', 'Interleukin-4', 'Interleukin-8', 'Male', 'Periodontal Index'] | 19,121,063 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C07.793.208.377'], ['A12.383.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Homocysteine, circulating vascular cell adhesion molecule and carotid atherosclerosis in postmenopausal vegetarian women and omnivores. | Since the adoption of vegetarian diets as a healthy lifestyle has become popular, the cardiovascular effects of long-term vegetarianism need to be explored. The present study aimed to compare the presence and severity of carotid atherosclerosis (CA), and the blood levels of Vitamin B12, homocysteine (Hcy) and soluble v... | ['Biomarkers', 'Carotid Artery Diseases', 'Diet, Vegetarian', 'Female', 'Follow-Up Studies', 'Homocysteine', 'Humans', 'Immunoassay', 'Middle Aged', 'Postmenopause', 'Prognosis', 'Retrospective Studies', 'Severity of Illness Index', 'Time Factors', 'Ultrasonography', 'Vascular Cell Adhesion Molecule-1'] | 16,005,009 | [['D23.101'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E02.642.249.300', 'G07.203.650.240.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['M01.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transfection of genetically encoded photoswitchable probes for STORM imaging. | Conventional fluorescence microscopy is limited by its spatial resolution, leaving many biological structures too small to be studied in detail. Stochastic optical reconstruction microscopy (STORM) is a method for superresolution fluorescence imaging based on the high accuracy localization of individual fluorophores. I... | ['Animals', 'Cell Line', 'Chlorocebus aethiops', 'Fluorescent Dyes', 'Luminescent Proteins', 'Microscopy, Fluorescence', 'Optical Imaging', 'Plasmids', 'Staining and Labeling', 'Transfection'] | 23,734,026 | [['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D12.776.532'], ['E01.370.350.515.458', 'E05.595.458'], ['E01.370.350.589', 'E05.642'], ['G05.360.600'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identifying actives from HTS data sets: practical approaches for the selection of an appropriate HTS data-processing method and quality control review. | High-throughput screening (HTS) has achieved a dominant role in drug discovery over the past 2 decades. The goal of HTS is to identify active compounds (hits) by screening large numbers of diverse chemical compounds against selected targets and/or cellular phenotypes. The HTS process consists of multiple automated step... | ['Biological Assay', 'Data Interpretation, Statistical', 'Dimethyl Sulfoxide', 'Drug Discovery', 'False Positive Reactions', 'High-Throughput Screening Assays', 'Quality Control', 'Validation Studies as Topic'] | 21,160,066 | [['E05.091'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['D02.886.640.150'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['E01.354.506'], ['E05.916.680'], ['J01.897.608'], ['E05.337.925', 'N05.715.360.335.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721. | The molecular mechanisms of wogonin-induced apoptosis of human hepatoma SMMC-7721 cells are reported. Wogonin treatment resulted in significant inhibition of SMMC-7721 cells in a time-dependent and concentration-dependent manner. Typical morphological changes and apoptotic blebbing in SMMC-7721 cells were observed afte... | ['Annexin A5', 'Apoptosis', 'Blotting, Western', 'Carcinoma, Hepatocellular', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Shape', 'Colorimetry', 'DNA Fragmentation', 'DNA, Neoplasm', 'Flavanones', 'Humans', 'Propidium', 'Proto-Oncogene Proteins c-bcl-2', 'Reverse Transcriptase Polymerase Chain Reaction', 'Tetrazolium Salts... | 16,926,629 | [['D12.776.157.125.050.100'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.320'], ['E05.196.92... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of electroconvulsive seizures on pattern separation. | Strategies employing different techniques to inhibit or stimulate neurogenesis have implicated a role for adult-born neurons in the therapeutic effect of antidepressant drugs, as well as a role in memory formation. Electroconvulsive seizures (ECS), an animal model of electroconvulsive therapy, robustly stimulate hippoc... | ['Animals', 'Behavior, Animal', 'Cell Differentiation', 'Disease Models, Animal', 'Electroconvulsive Therapy', 'Hippocampus', 'Male', 'Neurogenesis', 'Neurons', 'Pattern Recognition, Visual', 'Psychomotor Performance', 'Rats'] | 25,850,383 | [['B01.050'], ['F01.145.113'], ['G04.152'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['F04.570.200.583', 'F04.669.224.300'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G04.152.912', 'G07.345.500.325.377.687', 'G08.686.784.170.450.500', 'G11.561.620'], ['A08.675', 'A11.671'], ['F02.463.593.524.5... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lipophilic cations: a group of model substrates for the multidrug-resistance transporter. | The possibility that simple lipophilic cations such as tetraphenylphosphonium (TPA+), triphenylmethylphosphonium (TPMP+), and diphenyldimethylphosphonium (DDP+) are substrates for the multidrug-resistance transport protein, P-glycoprotein, was tested. Hamster cells transfected with and overexpressing mouse mdr1 or mous... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Adenosine Triphosphate', 'Animals', 'Arsenicals', 'CHO Cells', 'Cations', 'Cell Survival', 'Cricetinae', 'Electrophoresis, Polyacrylamide Gel', 'Gramicidin', 'Membrane Glycoproteins', 'Mutation', 'Onium Compounds', 'Organophosphorus Compounds', 'Substrate Spe... | 1,371,401 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D01.075', 'D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A simple and efficient genetic transformation method of Ganoderma weberianum. | In this study, the Agrobacterium tumefaciens-mediated transformation method for Ganderma weberianum has been established. Driven by the cauliflower mosaic virus (CaMV) 35S promoter, the hygromycin phosphotransferase (hpt), â-glucuronidase (uidA), and enhanced green fluorescent protein (egfp) genes have been efficiently... | ['Agrobacterium tumefaciens', 'Ganoderma', 'Genetic Techniques', 'Genetic Vectors', 'Green Fluorescent Proteins', 'Transformation, Genetic'] | 25,655,754 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['B01.300.179.120.760.338'], ['E05.393'], ['G05.360.337'], ['D12.776.532.265'], ['G05.728.865']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum 25-hydroxyvitamin D and orthostatic hypotension in old people: the Pro.V.A. study. | Interest in the association between serum 25-hydroxyvitamin D (25OHD) and blood pressure has increased because recent research showed a close relationship between them, but there is still little information on the possible association between 25OHD and orthostatic hypotension. The aim of this study was to explore the r... | ['Aged', 'Aged, 80 and over', 'Aging', 'Biomarkers', 'Blood Pressure', 'Cohort Studies', 'Cross-Sectional Studies', 'Female', 'Humans', 'Hypotension, Orthostatic', 'Italy', 'Logistic Models', 'Male', 'Prevalence', 'Vitamin D'] | 24,914,191 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Predicting international students' clinical and academic grades using two language tests (IELTS and C-test): A correlational research study. | Academic English tests are used to ascertain if international English as a Second Language nursing students have sufficient language skills to commence their nursing degrees, and later, if they have sufficient English for nursing registration. However, an academic English test may not be appropriate for clinical contex... | ['Australia', 'Educational Measurement', 'Humans', 'Language Arts', 'Language Tests', 'Nurses, International', 'Students, Nursing'] | 30,384,083 | [['Z01.639.100', 'Z01.678.100.373'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.423'], ['F04.711.513.240'], ['M01.526.407.717', 'M01.526.485.650.662', 'N02.360.650.662'], ['M01.848.769.685']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Availability of primate species, research, and management in China. | Approximately 30 institutions are currently engaged in primate research and management in China. New studies record 20 species of primates and their distribution throughout China. | ['Animals', 'China', 'Female', 'Male', 'Primates', 'Research'] | 1,803,008 | [['B01.050'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988'], ['H01.770.644']] | ['Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Caudate nucleus is critically involved in trace eyeblink conditioning. | The basal ganglia are a collection of brain regions involved with motor planning and initiation. The major site of cortical and thalamic input into the basal ganglia network is the striatum, which includes a differentiated caudate nucleus (CN) and the putamen in rabbits. Trace eyeblink conditioning (EBC) is a forebrain... | ['Adaptation, Physiological', 'Animals', 'Blinking', 'Caudate Nucleus', 'Conditioning, Eyelid', 'Female', 'Rabbits'] | 19,923,285 | [['G07.025', 'G16.012.500'], ['B01.050'], ['G11.561.731.127', 'G14.152'], ['A08.186.211.200.885.287.249.487.550.184'], ['F02.463.425.179.408'], ['B01.050.150.900.649.313.968.700']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors that impact health-related quality of life over time for individuals with head and neck cancer. | OBJECTIVES/HYPOTHESIS: To identify sociodemographic, behavioral, and clinical factors associated with health-related quality of life (HRQOL) for head and neck cancer (HNC) patients over time.STUDY DESIGN: A population-based longitudinal cohort study.METHODS: Newly diagnosed HNC patients (N = 587) were administered the ... | ['Adult', 'African Americans', 'Aged', 'European Continental Ancestry Group', 'Female', 'Head and Neck Neoplasms', 'Health Status', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Quality of Life', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Survivors'] | 27,224,024 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['M01.686.508.400'], ['C04.588.443'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M0... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Pain syndromes and etiologies in ambulatory AIDS patients. | Ambulatory AIDS patients participating in a quality of life study were recruited for an assessment of pain syndromes. Of 274 patients with pain, 151 (55%) consented to the assessment which included a clinical interview, neurologic examination, and review of medical records. The number, type, and etiology of pains were ... | ['Adolescent', 'Adult', 'Female', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Outpatients', 'Pain', 'Prospective Studies', 'Syndrome'] | 9,150,284 | [['M01.060.057'], ['M01.060.116'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.643.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Magnetic resonance imaging of the bone marrow in patients with leukemia, aplastic anemia, and lymphoma. | Magnetic resonance imaging (MRI) of the bone marrow was performed in 29 patients with leukemia, aplastic anemia, or lymphoma who were scheduled for bone marrow transplantation, and in 12 normals. T1-weighted coronal images (TR600/TE40) of the pelvis and proximal femurs demonstrated marrow pathology in adult patients. A... | ['Adolescent', 'Adult', 'Anemia, Aplastic', 'Bone Marrow', 'Child', 'Female', 'Hodgkin Disease', 'Humans', 'Leukemia, Lymphoid', 'Leukemia, Myeloid', 'Leukemia, Myeloid, Acute', 'Magnetic Resonance Spectroscopy', 'Male'] | 3,460,974 | [['M01.060.057'], ['M01.060.116'], ['C15.378.071.085', 'C15.378.190.223.250'], ['A15.382.216'], ['M01.060.406'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428', 'C15.604.515.560', 'C20.683.515.528'], ['C04.557.337.539'], ['C04.557.3... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk factors for invasive Haemophilus influenzae type b in Los Angeles County children 18-60 months of age. | Potential factors that confer risk or protection for invasive Haemophilus influenzae type b disease were evaluated in Los Angeles County children 18-60 months of age by case-control methods. In this age group, 79 H. influenzae type b cases were identified by overlapping surveillance methods, and 221 random controls wer... | ['Age Factors', 'Bacterial Vaccines', 'Breast Feeding', 'Case-Control Studies', 'Child, Preschool', 'Comorbidity', 'Ethnic Groups', 'Family Characteristics', 'Haemophilus Infections', 'Haemophilus influenzae', 'Housing', 'Humans', 'Immunization', 'Income', 'Infant', 'Logistic Models', 'Los Angeles', 'Medicare', 'Popula... | 1,415,144 | [['N05.715.350.075', 'N06.850.490.250'], ['D20.215.894.135'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['M01.686.754', 'N01.224.317... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industr... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
In silico evolutionary analysis of Helicobacter pylori outer membrane phospholipase A (OMPLA). | BACKGROUND: In the past decade, researchers have proposed that the pldA gene for outer membrane phospholipase A (OMPLA) is important for bacterial colonization of the human gastric ventricle. Several conserved Helicobacter pylori genes have distinct genotypes in different parts of the world, biogeographic patterns that... | ['Bacterial Outer Membrane Proteins', 'Computational Biology', 'Evolution, Molecular', 'Helicobacter pylori', 'Molecular Sequence Data', 'Phospholipases A1', 'Phylogeny', 'Sequence Analysis, DNA'] | 22,974,200 | [['D12.776.097.120', 'D12.776.543.100'], ['H01.158.273.180', 'L01.313.124'], ['G05.045.250', 'G16.075.250'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['L01.453.245.667'], ['D08.811.277.352.100.680.750.875'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Hallux proximal phalanx Akin-Scarf osteotomy. | Numerous hallux proximal phalanx osteotomies have been described, but the Akin-type varisation or adduction osteotomies are currently the most commonly used by foot and ankle surgeons. This article describes the hallux proximal phalanx Akin-Scarf osteotomy. This osteotomy combines the inherent stability of the Scarf-ty... | ['Foot Bones', 'Foot Deformities', 'Hallux', 'Humans', 'Metatarsal Bones', 'Osteotomy'] | 14,729,996 | [['A02.835.232.043.300'], ['C05.330'], ['A01.378.610.250.300.792.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.300.492'], ['E04.555.580']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of mRNA expression of transcription factors in glucocorticoid sensitivity of peripheral blood mononuclear cells and disease state in rheumatoid arthritis. | OBJECTIVE: To investigate the mechanisms underlying glucocorticoid (GC) resistance in rheumatoid arthritis (RA), we evaluated the suppressive effects of prednisolone (PSL) or methylprednisolone (MPSL) on the blastogenesis of peripheral blood mononuclear cells (PBMC). We also measured the expression of mRNA for transcri... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthritis, Rheumatoid', 'Drug Resistance', 'Female', 'Glucocorticoids', 'Humans', 'Leukocytes, Mononuclear', 'Lymphocyte Activation', 'Male', 'Methylprednisolone', 'Middle Aged', 'Prednisolone', 'RNA, Messenger', 'Receptors, Glucocorticoid', 'Transcription Factor AP-1', 'Transcri... | 14,994,389 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G07.690.773.984'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['E01... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of serum CEA, PHI, and TPA as tumor markers in breast cancer patients. | The purpose of this study was to evaluate the clinical significance of different serum tumor markers in patients with breast cancer who developed recurrent disease. Determined were tissue polypeptide antigen (TPA), carcinoembryonic antigens (CEA), and phosphohexose isomerase (PHI). Serum samples of 411 breast cancer pa... | ['Breast Neoplasms', 'Carcinoembryonic Antigen', 'Female', 'Glucose-6-Phosphate Isomerase', 'Humans', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Peptides', 'Tissue Polypeptide Antigen'] | 3,568,016 | [['C04.588.180', 'C17.800.090.500'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['D08.811.399.475.200.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C23.550.727.650'], ['C04.697.655', 'C23.550.727.655'], ['D12.644'], ['D... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Latent Structure of Dictionaries. | How many words-and which ones-are sufficient to define all other words? When dictionaries are analyzed as directed graphs with links from defining words to defined words, they reveal a latent structure. Recursively removing all words that are reachable by definition but that do not define any further words reduces the ... | ['Dictionaries as Topic', 'Humans', 'Learning', 'Semantics'] | 27,424,842 | [['L01.178.682.192.836.285'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['L01.559.598.745']] | ['Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Magnetic resonance imaging in cervical cord birth injury. | Three children who sustained cervical cord injury due to birth trauma are described. The clinical and radiological data, and the central nervous system pathology of one child, illustrate the advantages and feasibility of magnetic resonance imaging in ventilator-dependent children with cervical cord lesions. | ['Birth Injuries', 'Brain', 'Evaluation Studies as Topic', 'Humans', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Respiration, Artificial', 'Spinal Cord', 'Spinal Cord Injuries'] | 2,330,237 | [['C16.614.131', 'C26.141'], ['A08.186.211'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.350.825.500'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['A08.186.854'], ['C10.228.854.763', 'C10.900.850', 'C26.819']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
From sucker to saint: moralization in response to self-threat. | When people's rationality and agency are implicitly called into question by the more expedient behavior of others, they sometimes respond by feeling morally superior; this is referred to as the sucker-to-saint effect. In Experiment 1, participants who completed a tedious task and then saw a confederate quit the same ta... | ['Cooperative Behavior', 'Culture', 'Female', 'Game Theory', 'Humans', 'Interpersonal Relations', 'Male', 'Motivation', 'Retrospective Moral Judgment', 'Self Concept', 'Social Justice', 'Social Perception'] | 18,816,289 | [['F01.145.813.115'], ['I01.076.201.450', 'I01.880.853.100'], ['G17.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.658', 'F01.752.543.500.750'], ['K01.752.566.479.113.750', 'N05.350.244.750'], ['F01.752.747.792'], ['I01.880.604.473.700', 'K01.752.566.479.830.750', 'N03.706.437.700', 'N05... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Teflon sponge shunt for recurrent arachnoid cyst. | A 50-year-old female presented with complaints of progressive ataxia. Investigations showed a large intradural arachnoid cyst located anterior to the brainstem. Following marsupialization of the cyst she improved remarkably in her symptoms. The symptoms recurred nine months later and investigations revealed recurrence ... | ['Arachnoid Cysts', 'Biocompatible Materials', 'Cisterna Magna', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Polytetrafluoroethylene', 'Subarachnoid Space'] | 18,040,114 | [['C04.182.044', 'C04.588.614.250.387.100', 'C10.500.142.100', 'C10.551.240.375.100', 'C16.131.666.142.100'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A08.186.566.166.686.351'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['D05.750.395.616', 'D25.720.395.61... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Quantifying the formation of nitrogen-containing disinfection by-products in chlorinated water using absorbance and fluorescence indexes. | Among known but unregulated disinfection by-products (DBPs), several nitrogenous species (N-DBPs) have been found in drinking waters. While concentrations of N-DBP are much lower than those of trihalomethanes (THMs) and haloacetic acids (HAAs), their potential toxicity is higher. In this study the relationships between... | ['Chlorine', 'Disinfection', 'Nitrogen', 'Spectrometry, Fluorescence', 'Spectrophotometry, Ultraviolet'] | 21,245,551 | [['D01.268.380.150', 'D01.362.225'], ['N06.850.780.200.450.850.375'], ['D01.268.604', 'D01.362.625'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Molecular phylogenetics of the hominoid Y chromosome. | The Human Y-chromosome plays a central role in sex determination, and is composed of DNA sequences homologous to the Y-chromosome, families of Y-specific repetitive DNA sequences, and single copy sequences. We investigated the chromosomal location of Y-specific DNA sequences, in the chimpanzee (Pan troglodytes), gorill... | ['Amelogenin', 'Animals', 'Dental Enamel Proteins', 'Evolution, Molecular', 'Gorilla gorilla', 'Hominidae', 'Humans', 'In Situ Hybridization, Fluorescence', 'Pan troglodytes', 'Phylogeny', 'Pongo pygmaeus', 'Telomere', 'Y Chromosome'] | 9,747,032 | [['D12.776.231.500'], ['B01.050'], ['D12.776.231'], ['G05.045.250', 'G16.075.250'], ['B01.050.150.900.649.313.988.400.112.400.375'], ['B01.050.150.900.649.313.988.400.112.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Molecular characterization and expression profile of the melatonin receptor MT1 in the ovary of Tianzhu white yak (Bos grunniens). | Melatonin plays crucial roles in a wide range of ovarian physiological functions via the melatonin receptors (MRs). Structure and function of MRs have been well studied in sheep, cattle, and humans, but little information exists on the genetic characterization and function of these receptors in the ovary of the white y... | ['Amino Acid Sequence', 'Animals', 'Cattle', 'DNA, Complementary', 'Female', 'Gene Expression Regulation', 'Granulosa Cells', 'Humans', 'Melatonin', 'Open Reading Frames', 'Ovary', 'Pregnancy', 'RNA, Messenger', 'Receptor, Melatonin, MT1'] | 26,482,006 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.308'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812', 'A11.436.329'], ['B01.050.150.900.649.313.988.400.112.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chimeric CD19 antibody mediates cytotoxic activity against leukemic blasts with effector cells from pediatric patients who received T-cell-depleted allografts. | Relapse is a major problem after transplantation in children with acute B-lineage leukemias, and new therapies are needed to increase graft-versus-leukemia (GvL) effects without inducing graft-versus-host disease (GvHD). Here, we studied the ability of effector cells recovered from patients after transplantation with p... | ['Antibodies', 'Antibody-Dependent Cell Cytotoxicity', 'Antigens, CD19', 'Child', 'Cytotoxicity Tests, Immunologic', 'Humans', 'Killer Cells, Natural', 'Lymphocyte Depletion', 'Peripheral Blood Stem Cell Transplantation', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Recombinant Fusion Proteins', 'T-Lymphocytes, R... | 14,764,538 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.287.070'], ['D23.050.301.264.035.119', 'D23.050.301.264.051.119', 'D23.050.301.500.600.200', 'D23.050.705.552.600.200', 'D23.101.100.110.119', 'D23.101.100.150.119'], ['M01.060.406'], ['E01.370.225.812.160', 'E05.200.812.160', 'E0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Asbestos in talc. | Talc deposits include asbestos minerals such as chrysotile and amphiboles that may be carried over into consumer products. Optical microscopy and x-ray diffraction analyses may not reveal their presence. Examples are given of electron microscopy procedures that permit detection and measurement. | ['Asbestos', 'Microscopy, Electron', 'Microscopy, Polarization', 'Talc', 'X-Ray Diffraction'] | 4,470,924 | [['D01.578.725.050', 'D01.837.725.700.760.070'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.350.515.624', 'E05.595.624'], ['D01.524.500.850', 'D01.578.725.500.800', 'D01.837.725.700.760.535.800'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glycemic control and pregnancy outcomes in women with type 2 diabetes from Poland. The impact of pregnancy planning and a comparison with type 1 diabetes subjects. | The number of pregnancies complicated by type 2 diabetes mellitus (T2DM) is growing; however, their clinical characteristics remain incomplete. We aimed to assess clinical characteristics, glycemic control, and selected pregnancy outcomes in pregestational T2DM from Poland and to compare them with those of T1DM. We ana... | ['Adult', 'Age Factors', 'Body Mass Index', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Fetal Macrosomia', 'Glycated Hemoglobin A', 'Humans', 'Infant, Newborn', 'Poland', 'Preconception Care', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Trimester, First', 'Pregnancy in Diabetics', 'Prenatal Ca... | 21,528,433 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['C13.703.170.500', 'C13.703.277.570', 'C13.703.726.570', 'C16.300.570', ... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues. | Vascular endothelial growth factor-C (VEGF-C) functions specifically to induce lymphangiogenesis. We examined the relationship between expression of VEGF-C and clinicopathological features in patients with colorectal cancer. The expression of VEGF-C in the 99 primary tumours and 18 metastatic lymph nodes from colorecta... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Colorectal Neoplasms', 'Endothelial Growth Factors', 'Female', 'Humans', 'Immunohistochemistry', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Vascular Endothelial Growth Factor C'] | 10,970,690 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Caspase-mediated apoptosis in sponges: cloning and function of the phylogenetic oldest apoptotic proteases from Metazoa. | Sponges (phylum Porifera) represent the phylogenetically oldest metazoan phylum. These animals have complex cell adhesion and powerful immune systems which allow the formation of a distinct body plan. Consequently, an apoptotic machinery has to be predicted that allows sponges to eliminate unwanted cells accumulating d... | ['Amino Acid Sequence', 'Animals', 'Apoptosis', 'Caspase 3', 'Caspase Inhibitors', 'Caspases', 'Cloning, Molecular', 'Coumarins', 'Endopeptidases', 'Enzyme Inhibitors', 'Isoenzymes', 'Molecular Sequence Data', 'Oligopeptides', 'Phylogeny', 'Porifera', 'Sequence Alignment'] | 12,581,862 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D27.505.519.389.745.325.500'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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