Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Portable chest radiography: comparison of high-resolution digital displays with laser printed digital film. | Computed radiology is a radiographic imaging technology that generates a conventional radiographic image in digital form. The image can be recorded on a laser sensitive film or archived to a digital storage device and displayed on a video monitor. This study was performed to evaluate the adequacy of reporting digitised... | ['Bronchography', 'Computer Systems', 'Computer Terminals', 'Critical Care', 'Data Display', 'Equipment Design', 'Evaluation Studies as Topic', 'Humans', 'Information Storage and Retrieval', 'Lasers', 'Lung', 'Lung Diseases', 'Observer Variation', 'Pleural Diseases', 'Radiographic Image Enhancement', 'Radiography, Thor... | 9,663,305 | [['E01.370.350.700.730.100', 'E01.370.386.100'], ['L01.224.230'], ['L01.224.230.260.115.500'], ['E02.760.190', 'N02.421.585.190'], ['F02.784.412.221', 'L01.296'], ['E05.320'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['E07.632.490', 'E07.710.52... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The measurement of locus of control: assessing more than meets the eye? | Ambiguities in the conceptions and measurement of locus of control were investigated in this study. Specifically, some psychometric properties of several widely used measures of perceived behavior-outcome contingency, interpersonal power, and social self-efficacy were assessed. To different degrees, the results indicat... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Internal-External Control', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Psychometrics', 'Reproducibility of Results', 'Self Concept'] | 10,654,847 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F01.829.401'], ['M01.060.116.630'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['F01.752.747.792']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
New insights into NF-kappaB regulation and function. | NF-kappaB (nuclear factor-kappaB) transcription factors have multiple critical roles in the regulation of immune responses. In unstimulated cells, NF-kappaB proteins are sequestered in the cytoplasm by IkappaB inhibitory proteins. Various immune stimuli induce the IkappaB kinase (IKK) to phosphorylate IkappaBs, trigger... | ['Animals', 'Humans', 'I-kappa B Kinase', 'NF-kappa B', 'NF-kappa B p52 Subunit', 'Signal Transduction', 'TNF Receptor-Associated Factor 2', 'TNF Receptor-Associated Factor 3', 'Transcription Factor RelA', 'Ubiquitin-Conjugating Enzymes', 'Ubiquitination'] | 18,775,672 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['D12.776.157.687.497', 'D12.776.260.600.186', 'D12.776.660.600.186', 'D12.776.660.720.497', 'D12.776.930.60... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suboptimal management of acute food-allergic reactions by patients, emergency departments and general practitioners. | Suboptimal food allergy management by patients and doctors. | ['Acute Disease', 'Adult', 'Bronchodilator Agents', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Epinephrine', 'Female', 'Food Hypersensitivity', 'Glucocorticoids', 'Histamine Antagonists', 'Humans', 'Male', 'Middle Aged', 'Netherlands', 'Physicians, Family'] | 19,226,303 | [['C23.550.291.125'], ['M01.060.116'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['C2... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Benign recurrent intrahepatic cholestasis]. | HISTORY AND FINDINGS: When aged 25 years, a now 38-year-old man had acute hepatitis A with jaundice. In the subsequent years he had recurrent jaundice with severe itching and insomnia. Multiple hospital admissions with laparoscopy and liver biopsy failed to find a cause. On admission he was again jaundiced, but there w... | ['Acute Disease', 'Adult', 'Cholestasis, Intrahepatic', 'Chronic Disease', 'Drug Therapy, Combination', 'Hepatitis A', 'Humans', 'Male', 'Recurrence', 'Remission Induction', 'Time Factors'] | 8,829,906 | [['C23.550.291.125'], ['M01.060.116'], ['C06.130.120.135.250', 'C06.552.150'], ['C23.550.291.500'], ['E02.319.310'], ['C01.925.440.420', 'C01.925.782.687.359.500', 'C06.552.380.705.422'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.937'], ['E02.860'], ['G01.910.857']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha. | Adaptation to hypoxia is mediated by transactivation of hypoxia-responsive genes by hypoxia-inducible factor-1 (HIF-1) in complex with the CBP and p300 transcriptional coactivators. We report the solution structure of the cysteine/histidine-rich 1 (CH1) domain of p300 bound to the C-terminal transactivation domain of H... | ['Amino Acid Sequence', 'Animals', 'Asparagine', 'Escherichia coli', 'Humans', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Sequence Data', 'Nuclear Proteins', 'Protein Binding', 'Protein Conformation', 'Protein Folding', 'Protein Structure, Secondary',... | 11,959,990 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['E05.196.867.519'], ['E05.599.595'], ['L0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Acetone-celloidin method for the cytological and immunofluorescent study of cell cultures infected with various viruses]. | A method was worked out for the extraction of a cell monolayer from test tubes with the use of 10 per cent acetone solution of celloidin. This made it possible to carry out parallel cytologic and immunofluorescent studies of cultures infected with various viruses. In contrast to the alcohol-ether celloidin used in hist... | ['Acetone', 'Animals', 'Cattle', 'Cell Line', 'Collodion', 'Cytological Techniques', 'Fluorescent Antibody Technique', 'Virus Cultivation', 'Viruses'] | 3,909,629 | [['D02.522.064'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['D25.720.099.500.439', 'J01.637.051.720.099.500.439'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.58... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A Hospital-Level Intervention to Improve Outcomes of Opioid Exposed Newborns. | PURPOSE: The purpose of this quality improvement project was to determine if non-pharmacologic strategies such as a rooming-in approach to care for newborns at risk of developing neonatal abstinence syndrome (NAS) would reduce total length of stay (LOS) and reduce the need for pharmacologic treatment.DESIGN AND METHODS... | ['Female', 'Humans', 'Infant Care', 'Infant, Newborn', 'Length of Stay', 'Mothers', 'Neonatal Abstinence Syndrome', 'Opiate Substitution Treatment', 'Outcome Assessment, Health Care', 'Retrospective Studies', 'Severity of Illness Index'] | 31,352,111 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.088.120'], ['M01.060.703.520'], ['E02.760.400.480', 'N02.421.585.400.480'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['C16.614.610', 'C25.775.650', 'F03.900.650'], ['E02.319.620'], ['H01.770.644.145.431', 'N04.761.559.590', 'N... | ['Organisms [B]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Thermostable inulinases secreted by yeast and yeast-like strains from the Brazilian semi-arid region. | The use of inulinases provides an alternative to the chemical process of inulin hydrolysis to obtain fructose syrup, and can reduce processing steps, time, and costs in the food industry. The objective of this work was to screen the thermostable inulinases produced by yeast and yeast-like strains isolated from the Braz... | ['Brazil', 'Desert Climate', 'Enzyme Stability', 'Food Technology', 'Food-Processing Industry', 'Fructose', 'Fungal Proteins', 'Fungi', 'Glycoside Hydrolases', 'Hot Temperature', 'Hydrolysis', 'Inulin', 'Symbiosis', 'Time Factors', 'Yeasts'] | 19,353,366 | [['Z01.107.757.176'], ['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['E05.916.360', 'G02.111.700.500'], ['J01.576.423.850'], ['J01.576.423.200.400'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D12.776.354'], ['B01.300'], ['D08.811.277.450'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.7... | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Incorporation of flow injection analysis with dual-wavelength overlapping resonance Rayleigh scattering for rapid determination of malachite green and its metabolite in fish. | A flow injection analysis (FIA) system combined with dual-wavelength overlapping resonance Rayleigh scattering (DWO-RRS) has been established and validated for rapid determination of malachite green (MG) and its metabolite in fish samples. Under experimental condition, MG would react with Erythrosin (Ery) to form ion-a... | ['Animals', 'Erythrosine', 'Fishes', 'Flow Injection Analysis', 'Food Contamination', 'Hydrogen-Ion Concentration', 'Ions', 'Metals', 'Organometallic Compounds', 'Reproducibility of Results', 'Rosaniline Dyes', 'Scattering, Radiation', 'Spectrometry, Fluorescence', 'Surface-Active Agents'] | 24,769,380 | [['B01.050'], ['D02.455.426.779.347.350', 'D03.633.300.953.275.350', 'D04.711.347.350'], ['B01.050.150.900.493'], ['E05.196.460'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['G02.300'], ['D01.248.497'], ['D01.552'], ['D02.691'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Separation of gliadin at pH 3.1 in a polyacrylamide gel suitable for blotting procedures. | A polyacrylamide gel electrophoresis system for the separation of gliadin at acidic pH is described. The gel is cast at neutral pH with polymerization in 20 min. Equilibration of the gel to pH 3.1 takes place during the electrophoresis. The gel is highly uniform with good mechanical properties and therefore suitable fo... | ['Electrophoresis, Polyacrylamide Gel', 'Gliadin', 'Hydrogen-Ion Concentration', 'Immunosorbent Techniques', 'Plant Proteins', 'Triticum'] | 3,889,121 | [['E05.196.401.402', 'E05.301.300.319'], ['D12.776.765.433.500.500.400', 'D12.776.765.725.500.500.400'], ['G02.300'], ['E05.478.566.380', 'E05.601.470.380'], ['D12.776.765'], ['B01.650.940.800.575.912.250.822.918']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Poly(vinyl alcohol)-Thioxanthone as One-Component Type II Photoinitiator for Free Radical Polymerization in Organic and Aqueous Media. | A novel one-component type II polymeric photoinitiator, poly(vinyl alcohol)-thioxanthone (PVA-TX), is synthesized by a simple acetalization process and characterized. PVA-TX enables photopolymerization of methyl methacrylate and acrylamide in both organic and aqueous media. Photopolymerization proceeds even in the abse... | ['Acrylamide', 'Dimethylformamide', 'Free Radicals', 'Light', 'Methylmethacrylate', 'Photochemical Processes', 'Polymerization', 'Polyvinyl Alcohol', 'Solvents', 'Thioxanthenes', 'Water', 'Xanthones'] | 25,855,091 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['D02.065.463.387', 'D02.241.081.420.500.387'], ['D01.339', 'D02.389'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02.241.081.069.800.550.450', 'D05.750.716.822.111.650.605.450', 'D25.720.716.822.111.650.605.450', 'J01.637.051.720.71... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[A new psychophysiologic test, "The Information Test", and its possible use in cardiology]. | The authors describe a new psychophysiological test based on the use of commercially available television apparatuses and aimed at determining the efficiency of information processing. The use of the test in 346 people has demonstrated its acceptability for building up psychoemotional tension and detecting the hyperten... | ['Adolescent', 'Adult', 'Blood Pressure', 'Cardiovascular Diseases', 'Child', 'Coronary Disease', 'Diagnosis, Differential', 'Humans', 'Hypertension', 'Middle Aged', 'Neurocirculatory Asthenia', 'Psychological Tests'] | 6,492,585 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['M01.060.406'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['F03.080.500'], ['F04.711']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
End of life decisions in newborns in The Netherlands: medical and legal aspects of the Groningen protocol. | The international press has been full of blood chilling accounts concerning a supposedly new practice in the Netherlands of terminating the life of severely defective newborn babies with a protocol. Our aim is to give insight into the medical and legal aspects of this protocol and to describe its contents. The legal de... | ['Advisory Committees', 'Clinical Protocols', 'Critical Care', 'Euthanasia', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Netherlands'] | 16,929,815 | [['N03.706.742.500'], ['E02.183', 'N05.715.360.330.125'], ['E02.760.190', 'N02.421.585.190'], ['E02.760.905.199', 'I01.880.735.344.500', 'N02.421.585.905.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['Z01.542.651']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
cGMP stimulates renin secretion in vivo by inhibiting phosphodiesterase-3. | The interaction between renin, nitric oxide (NO), and its second messenger cGMP is controversial. cAMP is the stimulatory second messenger for renin but is degraded by phosphodiesterases (PDEs). We previously reported that increasing endogenous cGMP in rats by inhibiting its breakdown by PDE-5 stimulated renin secretio... | ["3',5'-Cyclic-AMP Phosphodiesterases", "3',5'-Cyclic-GMP Phosphodiesterases", 'Animals', 'Cyclic AMP', 'Cyclic GMP', 'Cyclic Nucleotide Phosphodiesterases, Type 3', 'Cyclic Nucleotide Phosphodiesterases, Type 5', 'Furosemide', 'Kinetics', 'Male', 'Milrinone', 'Nitric Oxide', 'Phosphodiesterase Inhibitors', 'Phosphoric... | 16,449,359 | [['D08.811.277.352.640.150', 'D12.644.360.008', 'D12.776.476.008'], ['D08.811.277.352.640.155', 'D12.644.360.009', 'D12.776.476.009'], ['B01.050'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Methodologic variants of DNA blood stain analysis: extraction in agarose and digoxigenin marking]. | DNA was extracted from 1 microliter bloodstains on glass, cotton cloth and paper using proteinase K digestion in a solution containing low gelling temperature agarose. This method is advantageous for small amounts of source material because the purifying procedures of other methods that contain a risk of loss of DNA, a... | ['Blood Grouping and Crossmatching', 'Blood Stains', 'DNA Probes', 'Digoxigenin', 'Digoxin', 'Female', 'Genetic Markers', 'Humans', 'Male', 'Sex Determination Analysis', 'Y Chromosome'] | 2,818,476 | [['E01.370.225.625.120', 'E01.370.225.812.385.120', 'E05.200.625.120', 'E05.200.812.385.120', 'E05.478.594.385.120'], ['I01.198.780.937.206'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D04.210.500.155.580.130.688.350'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Nrf2 protects against diabetic dysfunction of endothelial progenitor cells via regulating cell senescence. | Diabetes is associated with an increased risk of cardiovascular disease. A decrease in the number and functionality of endothelial progenitor cells (EPCs) leads to reduced endothelial repair and the development of cardiovascular disease. The aim of the present study was to explore the effect and underlying mechanisms o... | ['Animals', 'Cell Movement', 'Cells, Cultured', 'Cellular Senescence', 'Diabetes Mellitus, Experimental', 'Endothelial Progenitor Cells', 'Male', 'Malondialdehyde', 'Mice', 'Mice, Inbred C57BL', 'NF-E2-Related Factor 2', 'Nitric Oxide', 'Oxidative Stress', 'Reactive Oxygen Species', 'Superoxide Dismutase', 'Vascular En... | 29,901,179 | [['B01.050'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['G04.043'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A11.148.174', 'A11.436.275.182'], ['D02.047.700'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Scoliosis Surgery Significantly Impacts Motor Abilities in Higher-functioning Individuals with Spinal Muscular Atrophy1. | BACKGROUND: Weakness affects motor performance and causes skeletal deformities in spinal muscular atrophy (SMA). Scoliosis surgery decision-making is based on curve progression, pulmonary function, and skeletal maturity. Benefits include quality of life, sitting balance, and endurance. Post-operative functional decline... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Movement Disorders', 'Orthopedic Procedures', 'Outcome and Process Assessment, Health Care', 'Postoperative Complications', 'Scoliosis', 'Spinal Muscular Atrophies of Childhood'] | 32,083,590 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.662'], ['E02.718', 'E04.555'], ['N04.761.559', 'N05.715.360.575'], ['C23.550.767'], ['C05.116.900.800.875'], ['C10... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Scoring Tool to Estimate the Survival of Elderly Patients With Brain Metastases from Esophageal Cancer Receiving Whole-brain Irradiation. | BACKGROUND/AIM: Elderly patients with metastatic esophageal cancer may benefit from individualized therapies. A tool to predict the survival of such patients with brain metastases was created.PATIENTS AND METHODS: In 11 elderly patients (?65 years) receiving whole-brain irradiation (WBI) for brain metastases from esoph... | ['Aged', 'Brain Neoplasms', 'Cranial Irradiation', 'Esophageal Neoplasms', 'Female', 'Humans', 'Male', 'Prognosis', 'Survival Rate', 'Treatment Outcome'] | 32,132,071 | [['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E02.815.190'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Heterogeneity in the biological and cultural determinants of high-density lipoprotein cholesterol in five North American populations: the Lipid Research Clinics Family Study. | Heterogeneity in the source of familial resemblance for high-density lipoprotein (HDL) cholesterol in 5 different Lipid Research Clinics (Cincinnati, Iowa, Minnesota, Oklahoma and Stanford) was assessed using a general linear model for cultural and biological inheritance. No evidence of heterogeneity was found in any o... | ['Cholesterol, HDL', 'Environment', 'Female', 'Genetic Variation', 'Genetics, Population', 'Humans', 'Male', 'Models, Genetic', 'Phenotype', 'Statistics as Topic', 'United States'] | 2,613,250 | [['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['G16.500.275', 'N06.230'], ['G05.365'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['G05.695'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
The effects of lesions of telencephalic visual structures on visual discriminative performance in turtles (Chrysemys picta picta). | Ascending thalamotelencephalic visual pathways that terminate in specific telencephalic regions have been described in all reptiles studied. Although the anatomical data suggests that such telencephalic regions may play a role in visual processing in reptiles, few behavioral data are available. In the present study, th... | ['Animals', 'Brain Mapping', 'Cerebral Cortex', 'Discrimination, Psychological', 'Female', 'Male', 'Pattern Recognition, Visual', 'Superior Colliculi', 'Telencephalon', 'Thalamus', 'Turtles', 'Visual Pathways', 'Visual Perception'] | 6,886,065 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['F02.463.593.257'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['A08.186.211.132.659.800.816'], ['A08.186.211.200.885'], ['A08.186.211.200.317.826'], ['B01.050.150.900.833.848'], ['A08.612.220... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute systemic toxicity and antihypertensive activity of a novel todralazine analog in rats. | Acute intravenous toxicity and antihypertensive activity of KB1, a novel todralazine analog was investigated and compared with the effects of todralazine (Td) in normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rats. LD50 values were 72 mg.kg-1 for KB1, and 255 mg.kg-1 for Td in WKY and 43 mg.kg-1 o... | ['Animals', 'Blood Pressure', 'Hypertension', 'Male', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Todralazine'] | 8,036,918 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.907.489'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.700.400.300'], ['B01.050.050.199.520.760.390', 'B01.050.150.900.649.313.992.635.505.700.400.390'], ['D02.442.925', 'D03.383.710.605... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Holocarboxylase synthetase deficiency: report of a case with onset in late infancy. | A case of holocarboxylase synthetase (HCS) deficiency of late-infantile onset is presented and compared with the common manifestations in previously reported patients. Our patient had her first episode at 20 months followed by recurrent episodes of metabolic acidosis with ketolactic acidosis responding dramatically to ... | ['Age of Onset', 'Carbon-Nitrogen Ligases', 'Female', 'Humans', 'Infant', 'Male', 'Metabolism, Inborn Errors'] | 10,234,606 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['D08.811.464.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C16.320.565', 'C18.452.648']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Solid phase synthesis of oligonucleotides on a crosslinked polyacrylmorpholide support. | A suitable support for the synthesis of oligonucleotides by the phosphodi- and triester approaches was prepared by treatment of commercially available crosslinked polyacrylmorpholide beads with piperazine. The resulting polymer was used as a support for the synthesis of the self complementary decanucleotide d(T-C-G-G-A... | ['Base Sequence', 'Esters', 'Indicators and Reagents', 'Methods', 'Oligodeoxyribonucleotides', 'Oligonucleotides'] | 7,255,171 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.241.400'], ['D27.720.470.410'], ['E05.581'], ['D13.695.578.424.450'], ['D13.695.578.424']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
C825T polymorphism of the G-protein â3 subunit and its association with essential hypertension in Uzbek males. | OBJECTIVES: We investigated the association between the C825T polymorphism of the G-protein â3 subunit (GNB3) gene with essential hypertension (EH) and cardiovascular remodeling markers in Uzbek males.STUDY DESIGN: The study included 174 Uzbek men (mean age 49±10 years) with untreated EH of stage 1-2 and 60 normotensiv... | ['Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Case-Control Studies', 'Echocardiography', 'European Continental Ancestry Group', 'Genotype', 'Heterotrimeric GTP-Binding Proteins', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Protein Subunits', 'Tu... | 21,532,295 | [['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['M01.686.508.400'], ['G05.380'], ['D08.811.277.040.330.300.200', 'D12.644.36... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The Italian National Health Service expenditure on workplace prevention and safety (2006-2013): a national-level analysis. | BACKGROUND: The World Health Organization (WHO) stated that countries' health policies should give high priority to primary prevention of occupational health hazards. Scant data are available on health expenditure on workplace prevention and safety services and on its impact on occupational health outcomes in Italy and... | ['Health Expenditures', 'Health Policy', 'Health Promotion', 'Humans', 'Italy', 'National Health Programs', 'Preventive Medicine', 'Safety', 'Workplace', 'World Health Organization'] | 27,627,662 | [['N03.219.151.450', 'N05.300.385'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['N03.349.550'], ['H02.403.720.750'], ['N06.850.135.060.075'], ['N01.824.245.925', 'N04.452.677.97... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Real time control for reduced aeration and chemical consumption: a full scale study. | The use of the activated sludge process (ASP) for the nitrification/denitrification of wastewaters is commonplace throughout the UK and many other parts of the industrial world. Associated with this process are significant costs arising from aeration requirements and for selected sites, the need to provide an external ... | ['Air', 'Ammonia', 'Bioreactors', 'Nitrates', 'Nitrogen', 'Oxygen', 'Sewage', 'Time Factors', 'United Kingdom', 'Waste Disposal, Fluid', 'Water', 'Water Pollutants, Chemical'] | 20,418,611 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['D01.362.075', 'D01.625.050'], ['E07.115', 'J01.897.120.115'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.268.604', 'D01.362.625'], ['D01.268.185.550', 'D01.362.670'], ['D20.944.932.500'], ['G01.910.857'], ['Z01.542.363'], ['N06.850.780.200.800.800.890... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Primary tracheo-esophageal puncture voice restoration with laryngectomy. | In 1979 Singer and Blom introduced a technique of tracheo-esophageal puncture for restoration of voice in the post-laryngectomy patient. This procedure is usually done as a staged secondary procedure, six months after the primary laryngectomy. This study compares 13 patients who have had a laryngectomy and primary trac... | ['Aged', 'Female', 'Humans', 'Laryngectomy', 'Larynx, Artificial', 'Male', 'Middle Aged', 'Postoperative Complications', 'Punctures', 'Speech, Alaryngeal', 'Speech, Esophageal', 'Time Factors', 'Trachea'] | 3,712,547 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.580.369'], ['E07.695.450', 'E07.858.082.595'], ['M01.060.116.630'], ['C23.550.767'], ['E02.800', 'E04.665'], ['E02.760.169.063.500.727.541', 'E02.831.727.541'], ['E02.760.169.063.500.727.541.677', 'E02.831.727.541.677'], ['G01.910.857'], ['A04... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The physician in the technological age. | Translator's summary and notes: Karl Jaspers (1883-1969) argues that modern advances in the natural sciences and in technology have exerted transforming influence on the art of clinical medicine and on its ancient Hippocratic ideal, even though Plato's classical argument about slave physicians and free physicians retai... | ['Communication', 'Existentialism', 'Humanism', 'Humans', 'Medical Laboratory Science', 'Philosophy, Medical'] | 2,603,158 | [['F01.145.209', 'L01.143'], ['F02.739.418', 'K01.752.304'], ['K01.752.566.479.174', 'N05.350.835'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.010.450', 'J01.897.480'], ['K01.752.667']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Chemical force microscopy with active enzymes. | The adhesion forces have been measured between an atomic force microscope tip derivatized with an active enzyme, shikimate kinase, and an ATP mimic immobilized on a gold surface. Experiments with competitive binding of other ligands in solution show that the observed adhesion forces arise predominantly from specific in... | ['Binding, Competitive', 'Catalysis', 'Cell Adhesion', 'Enzymes', 'Gold', 'Kinetics', 'Ligands', 'Microscopy, Atomic Force', 'Phosphotransferases (Alcohol Group Acceptor)', 'Protein Binding', 'Shikimic Acid', 'Spectrophotometry, Infrared', 'Surface Plasmon Resonance', 'Time Factors'] | 11,325,745 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G02.130'], ['G04.022'], ['D08.811'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['D08.811.913.696.620'], ['G02.111.679', 'G03.808'], ['D02.241.22... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuromelanin of the human substantia nigra: a mixed-type melanin. | Model melanins, synthesized with different cysteinyldopamine/dopamine ratios in the incubates, were oxidized with KMnO4 and the resulting compounds were analyzed by HPLC. The ratios between a phaeomelanin-derived compound, thiazole-4,5-dicarboxylic acid (TDCA), and a compound derived from eumelanin, pyrrole-2,3,5-trica... | ['Autopsy', 'Chromatography, High Pressure Liquid', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Mass Spectrometry', 'Melanins', 'Potassium Permanganate', 'Substantia Nigra'] | 8,158,151 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.196.181.400.300'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D12.125.072.050.875.379', 'D23.767.620'], ['D01.530.700', 'D01.745.750'], ['A08.186.211.132.659.413.656']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Pathological prognostic factors in breast carcinoma. | OBJECTIVE: Pathological prognostic factors in breast cancer are now widely used to predict biological behavior of cancer and to plan its effective management. In this paper, we attempt to evaluate the reports from our histopathology laboratory spanning over a period of 4 years, to assess completeness in recording these... | ['Biopsy', 'Breast Neoplasms', 'Female', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Mastectomy', 'Medical Audit', 'Medical Records', 'Needs Assessment', 'Neoplasm Staging', 'Oman', 'Population Surveillance', 'Practice Guidelines as Topic', 'Predictive Value of Tests', 'Prognosis', 'Retrospective Studies'... | 11,533,822 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E04.466'], ['N04.761.700.250.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Prognosis of heart failure with preserved ejection fraction treated with â-blockers: A propensity matched study in the community. | BACKGROUND: The effect of treatment with â-blockers on the prognosis of patients newly diagnosed with heart failure with preserved ejection fraction (HFpEF) is unknown.OBJECTIVE: To analyze the relationship of commencing treatment with the â-blockers bisoprolol or carvedilol (CT-âB) with the prognosis of newly diagnose... | ['Adrenergic beta-Antagonists', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Propensity Score', 'Prospective Studies', 'Residence Characteristics', 'Stroke Volume', 'Treatment Outcome'] | 27,513,657 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['B01.050.150.900.649.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Estrogen and androgen receptors in the liver of cynomolgus monkeys (Macaca fascicularis). | Estrogen receptors (ER) and androgen receptors (AR) were evaluated in the hepatic cytosol from cynomolgus macaques to determine if there were differences associated with gender and endogenous hormone secretion. Saturable, high affinity binding (Kd = 0.2-0.8 nM) was demonstrated for both ER and AR from either male or fe... | ['Animals', 'Cytosol', 'Estradiol', 'Female', 'Liver', 'Macaca fascicularis', 'Male', 'Menstrual Cycle', 'Molybdenum', 'RNA, Messenger', 'Receptors, Androgen', 'Receptors, Estrogen', 'Sex Factors'] | 3,586,659 | [['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['A03.620'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['G08.686.605'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['D13.444.735.544'], ['D12.776.82... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relationship between aging and renal high-affinity sodium-dependent dicarboxylate cotransporter-3 expression characterized with antifusion protein antibody. | Sodium-dependent dicarboxylate cotransporter (NaDC), which is responsible for the transportation of intermediates of the Krebs cycle, has been implicated in extending the life span of drosophila. In the present study, we cloned an intracellular domain segment of human kidney NaDC-3, which is 75% identical to that of th... | ['Aging', 'Analysis of Variance', 'Animals', 'Antibodies', 'Blotting, Northern', 'Blotting, Western', 'Cloning, Molecular', 'Dicarboxylic Acid Transporters', 'Epitopes', 'Glutathione Transferase', 'Humans', 'Immunoenzyme Techniques', 'Kidney', 'Male', 'Membrane Proteins', 'Organic Anion Transporters, Sodium-Dependent',... | 14,570,853 | [['G07.345.124'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.60... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Restraints rock. | Restraint issues can create problems for staff, patients, and family. To meet the Joint Commission's restraint rules, a multidisciplinary education plan included alternative and distractive devices for patients. Use of restraints decreased markedly as staff members' knowledge and attitude improved. | ['Accidental Falls', 'Aged', 'Arkansas', 'Attitude of Health Personnel', 'Clinical Competence', 'Confusion', 'Education, Nursing, Continuing', 'Geriatric Nursing', 'Guideline Adherence', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Inservice Training', 'Interior Design and Furnishings', 'Nursing Assessment', 'Nu... | 15,127,531 | [['N06.850.135.122'], ['M01.060.116.100'], ['Z01.107.567.875.750.110'], ['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['I02.358.212.450', 'I02.358.462.399'], ['H02.478.676.236', 'N02.421.533.245'], ['N04.761.337', 'N05.715.3... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Technique... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Two SH2 domains of p120 Ras GTPase-activating protein bind synergistically to tyrosine phosphorylated p190 Rho GTPase-activating protein. | p120 GTPase-activating protein (GAP) is a negative regulator of Ras that functions at a key relay point in signal transduction pathways that control cell proliferation. Among other proteins, p120 GAP associates with p190, a GAP for the Ras-related protein, Rho. To characterize the p120.p190 interaction further, we used... | ['Animals', 'Baculoviridae', 'Cell Division', 'Cell Line', 'Cloning, Molecular', 'GTPase-Activating Proteins', 'Guanine Nucleotide Exchange Factors', 'Humans', 'Nuclear Proteins', 'Phosphoproteins', 'Phosphorylation', 'Protein Binding', 'Proteins', 'Repressor Proteins', 'Signal Transduction', 'Spodoptera', 'Tyrosine', ... | 7,629,101 | [['B01.050'], ['B04.280.065', 'B04.525.100'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['E05.393.220'], ['D12.644.360.325.150', 'D12.776.476.325.150'], ['D12.644.360.325.300', 'D12.776.476.325.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Idiopathic scoliosis, growth zones, magnetic therapy. | BACKGROUND: The study has been performed to investigate the influence of pulsed magnetic field on the bone growth plates to get new grounds of magneto therapy in AIS treatment.MATERIALS AND METHODS: Were used methods of "strong" and "weak" pulsed magnetic fields influence.RESULTS: Application of pulsed magnetic field c... | ['Animals', 'Growth Plate', 'Humans', 'Magnetic Field Therapy', 'Mice', 'Mice, Inbred C57BL', 'Rabbits', 'Scoliosis'] | 22,744,538 | [['B01.050'], ['A02.835.232.251.352'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.621'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.150.900.649.313.968.700'], ['C05.116.900.800.875']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Should doctors contribute more to the development of computer-based information systems at hospitals?]. | In our X-ray department we have used a commercially available database computer program to design a system for storing information about the X-ray examinations performed. The system runs on a local area network. We have been able to quickly modify the system in the light of feedback from the users. Using modern databas... | ['Hospital Information Systems', 'Microcomputers', 'Norway', 'Physicians', 'Radiology Department, Hospital'] | 2,339,407 | [['N04.452.442.452.452', 'N04.452.515.360'], ['L01.224.230.260.550'], ['Z01.542.816.374'], ['M01.526.485.810', 'N02.360.810'], ['N02.278.216.500.968.695', 'N04.452.442.452.422.695']] | ['Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Correlations between prolactin and somatotropic hormone in human breast cancer]. | The authors review any possible correlation between prolactin and growth hormone in human breast cancer. They find neither a significant relationship between growth hormone and breast cancer nor between prolactin and growth hormone. In many cases however, prolactin levels may be used as a neoplastic marker. The excess ... | ['Adult', 'Age Factors', 'Aged', 'Breast Neoplasms', 'Climacteric', 'Female', 'Growth Hormone', 'Humans', 'Menopause', 'Middle Aged', 'Neoplasm Metastasis', 'Postoperative Period', 'Prolactin'] | 7,209,107 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['G08.686.157', 'G08.686.841.249'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.157.500', 'G08.686.841.249.500'], ['M01.060.116.630'],... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of formaldehyde emission from building finishing materials at various temperatures in under heating system; ONDOL. | UNLABELLED: The objective of this research was to investigate the effect of various temperatures, room, 37 and 50 degrees C, on formaldehyde emission from floor materials, such as laminate and plywood floorings, and furniture materials, such as MDF and particleboard veneered with decorative paper foil, by desiccator's ... | ['Air Pollution, Indoor', 'Carcinogens, Environmental', 'Construction Materials', 'Floors and Floorcoverings', 'Formaldehyde', 'Heating', 'Humans', 'Korea', 'Temperature'] | 16,108,904 | [['N06.850.460.100.080'], ['D27.888.569.100.125'], ['J01.637.241'], ['J01.086.339.140'], ['D02.047.407'], ['N06.230.150.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.557', 'Z01.586.407'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.71... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[Evaluation of vascular risk factors in primary open-angle glaucoma using doppler sonography]. | UNLABELLED: Primary open angle glaucoma (POAG) is a syndrome of progressive optic neuropathy characterized by optic nerve head excavation and visual field defects. Poor correlation between intraocular pressure (IOP) and progression of glaucoma disease puts vascular mechanism in the center of attention. By color Doppler... | ['Adult', 'Aged', 'Blood Flow Velocity', 'Ciliary Arteries', 'Glaucoma, Open-Angle', 'Humans', 'Middle Aged', 'Pulse', 'Retinal Artery', 'Ultrasonography, Doppler, Color', 'Vascular Resistance'] | 12,630,340 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A07.015.114.248'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.370.380.650', 'G09.330.380.750'], ['A07.015.114.765', 'A07.015.611.647'], ['E01.370.350.850.850.850.850'], ['G09.33... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structural determinants for the action of grayanotoxin in D1 S4-S5 and D4 S4-S5 intracellular linkers of sodium channel alpha-subunits. | We located a novel binding site for grayanotoxin on the cytoplasmic linkers of voltage-dependent cardiac (rH1) or skeletal-muscle (mu 1) Na(+) channel isoforms (segments S4-S5 in domains D1 and D4), using the alanine scanning substitution method. GTX-modification of Na(+) channels, transiently expressed in HEK 293 cell... | ['Alanine', 'Animals', 'Cells, Cultured', 'Diterpenes', 'Ion Channel Gating', 'Kinetics', 'Mutagenesis', 'Protein Conformation', 'Rats', 'Sodium Channels', 'Toxins, Biological'] | 12,150,970 | [['D12.125.042'], ['B01.050'], ['A11.251'], ['D02.455.849.291'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['G01.374.661', 'G02.111.490'], ['G05.558'], ['G02.111.570.820.709'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.157.530.400.875', 'D12.776.543.550.450.875', 'D12.776.543.585.400.875'], ['D23.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Statistical methods for characterizing transfusion-related changes in regional oxygenation using near-infrared spectroscopy (NIRS) in preterm infants. | Near infrared spectroscopy (NIRS) is an imaging-based diagnostic tool that provides non-invasive and continuous evaluation of regional tissue oxygenation in real-time. In recent years, NIRS has shown promise as a useful monitoring technology to help detect relative tissue ischemia that could lead to significant morbidi... | ['Area Under Curve', 'Erythrocyte Transfusion', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Mesentery', 'Oxygen', 'Spectroscopy, Near-Infrared', 'Statistics, Nonparametric'] | 29,996,701 | [['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['E02.095.135.140.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['A01.923.047.025.600.451'], ['D01.268.185.550', 'D01.362.670'], ['E01.370.350.750', 'E05.196.867.851'], ['E05.318.740.99... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The characteristics of deceased and surviving patients with congestive heart failure at a department of internal medicine. | OBJECTIVES: We examined differences between surviving and deceased patients with congestive heart failure (HF).BACKGROUND: Congestive HF is a frequent disease with still increasing incidence, prevalence and poor prognosis. Patients have high mortality.PATIENTS AND METHODS: Over the period of 4 years we followed up 2 gr... | ['Aged', 'Aged, 80 and over', 'Female', 'Heart Failure', 'Humans', 'Male', 'Risk Factors', 'Survival Rate'] | 16,026,137 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.97... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism. | Qualitative impairments in communication, such as delayed language and poor interactive communication skills, are fundamental to the diagnosis of autism. Investigations into social communication in adult BTBR T+tf/J (BTBR) mice are needed to determine whether this inbred strain incorporates phenotypes relevant to the s... | ['Animal Communication', 'Animals', 'Autistic Disorder', 'Behavior, Animal', 'Female', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Neurologic Mutants', 'Motor Activity', 'Odorants', 'Ultrasonics', 'Urine', 'Vocalization, Animal'] | 20,345,893 | [['F01.145.113.055'], ['B01.050'], ['F03.625.164.113.500'], ['F01.145.113'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.150.900.649.313.992.635.505.500.550.480'], ['F01.145.632', 'G11.427.410.698'], ['G16.500.275.640', 'N06.... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Vision care in New Zealand. | This paper reports the results of a study into attitudes on vision care, vision care professionals and the utilisation of various ophthalmic aids and appliances in New Zealand. The majority (70%) of the 2000 persons questioned had received a visual examination by an optometrist or ophthalmologist and were either "very ... | ['Adolescent', 'Adult', 'Age Factors', 'Attitude to Health', 'Consumer Behavior', 'Eyeglasses', 'Female', 'Humans', 'Male', 'Middle Aged', 'New Zealand', 'Ophthalmology', 'Optometry', 'Prescriptions', 'Vision Disorders', 'Vision Tests'] | 6,587,210 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.100.150', 'N05.300.150'], ['F01.145.236'], ['E07.632.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.639.760.747', 'Z01.678.100.747'], ['H02.403.810.468'], ['H02.553'], ['N02.421.668.778'], ['C10.597.... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue | BACKGROUND: Detailed molecular analyses of cells from rheumatoid arthritis (RA) synovium hold promise in identifying cellular phenotypes that drive tissue pathology and joint damage. The Accelerating Medicines Partnership RA/SLE Network aims to deconstruct autoimmune pathology by examining cells within target tissues t... | ['Arthritis, Rheumatoid', 'Cryopreservation', 'Flow Cytometry', 'High-Throughput Screening Assays', 'Humans', 'Synovial Membrane'] | 29,996,944 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.36... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Creatinine reduction ratio on post-transplant day two as criterion in defining delayed graft function. | Delayed graft function (DGF) is a common complication after renal transplant, affecting its outcome. A common definition of DGF is the need for dialysis within the first week of transplantation, but this criterion has its drawbacks. We tried to validate an earlier and better defined parameter of DGF based on the creati... | ['Adult', 'Age Factors', 'Creatinine', 'Dialysis', 'Female', 'Graft Survival', 'Humans', 'Immunosuppressive Agents', 'Ischemia', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Risk Factors', 'Statistics as Topic', 'Time Factors', 'Tissue Donors', 'Treatment Outcome'] | 15,196,076 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D03.383.129.308.207'], ['E05.196.353', 'G02.186'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['C23.550.513'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.060.116.630'], ['E05.318.740.150.500... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
6-OHDA sympathectomy and exercise performance in the rat. | 6-hydroxydopamine (6-OHDA) was utilised for the study of the sympathetic nervous system in the resting rats and rats submitted to prolonged exercise. In order to reduce the acute physiological stress associated with an injection of 6-OHDA, beta-1 and alpha-1 adrenoceptors were blocked before the treatment leading to sy... | ['Animals', 'Blood Glucose', 'Fatty Acids, Nonesterified', 'Glucagon', 'Glycogen', 'Hydroxydopamines', 'Insulin', 'Kinetics', 'Liver', 'Male', 'Muscles', 'Norepinephrine', 'Oxidopamine', 'Physical Exertion', 'Rats', 'Rats, Inbred Strains', 'Sympathectomy, Chemical'] | 1,705,782 | [['B01.050'], ['D09.947.875.359.448.500'], ['D10.251.310'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D02.092.311.342.478', 'D02.455.426.559.389.657.166.175.342.478'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G01.374.661', 'G02.111.490... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Undaria pinnatifida a Rich Marine Reservoir of Nutritional and Pharmacological Potential: Insights into Growth Signaling and Apoptosis Mechanisms in Cancer. | Seaweeds are an important part of diet consumed in a different part of the world such as New Zealand, Ireland, Wales, and Asian countries including Korea, China, and Japan. In addition, seaweed is nutritious sources possessing health improving effects and therapeutic potential. Recently, one of the widely eaten seaweed... | ['Anticholesteremic Agents', 'Anticoagulants', 'Antineoplastic Agents', 'Antioxidants', 'Antiviral Agents', 'Apoptosis', 'Humans', 'Neoplasm Invasiveness', 'Neoplasms', 'Seaweed', 'Signal Transduction', 'Undaria'] | 30,616,379 | [['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D27.505.954.502.119'], ['D27.505.954.248'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D27.505.954.122.388'], ['G04.146.954.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.645', 'C23.550.727.645'], ['C04'], ['B05.080.750'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oogenesis in the leech Glossiphonia heteroclita (Annelida, Hirudinea, Glossiphoniidae) II. Vitellogenesis, follicle cell structure and egg shell formation. | By the end of previtellogenesis, the oocytes of Glossiphonia heteroclita gradually protrude into the ovary cavity. As a result they lose contact with the ovary cord (which begins to degenerate) and float freely within the hemocoelomic fluid. The oocyte's ooplasm is rich in numerous well-developed Golgi complexes showin... | ['Animals', 'Cell Membrane', 'Cytoplasmic Structures', 'Female', 'Leeches', 'Ovarian Follicle', 'Vitellogenesis'] | 16,930,656 | [['B01.050'], ['A11.284.149'], ['A11.284.430.214.190'], ['B01.050.500.091.426'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['G04.152.650.249.880', 'G08.686.784.310.500.880']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections. | During HIV type-1 (HIV-1), hepatitis C virus (HCV), and hepatitis B virus (HBV) infections, altered iron balance correlates with morbidity. The liver-produced hormone hepcidin dictates systemic iron homeostasis. We measured hepcidin, iron parameters, cytokines, and inflammatory markers in three cohorts: plasma donors w... | ['Acute-Phase Proteins', 'Anti-HIV Agents', 'Cohort Studies', 'Cytokines', 'HIV Infections', 'HIV-1', 'Hepatitis B', 'Hepatitis C', 'Hepcidins', 'Iron', 'Up-Regulation', 'Viral Load'] | 25,092,293 | [['D12.776.124.050'], ['D27.505.954.122.388.077.088'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.8... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enzymatic preparation of an artificial microRNA library. | MicroRNAs (miRNAs) are endogenous RNAs of about 20-25 nucleotides that play important roles in gene regulation. Based on miRNA backbones, artificial miRNAs, amiRNAs, can be constructed and expressed exogenously. AmiRNAs can function as natural miRNAs or siRNAs. AmiRNAs display higher expression levels and more potent s... | ['Animals', 'Base Sequence', 'Enzymes', 'Gene Library', 'Gene Targeting', 'Mice', 'MicroRNAs', 'Nucleic Acid Conformation', 'RNA Interference', 'Tumor Suppressor Protein p53'] | 19,836,357 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811'], ['G05.360.325'], ['E05.393.335'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G02.111.570.820.486', 'G05.360.580'], ['G05.308.203.374.790'], ['D12.776.157.687.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Detecting the violation of variance homogeneity in mixed models. | Mixed-effects models are increasingly used in many areas of applied science. Despite their popularity, there is virtually no systematic approach for examining the homogeneity of the random-effects covariance structure commonly assumed for such models. We propose two tests for evaluating the homogeneity of the covarianc... | ['Arthritis, Rheumatoid', 'Humans', 'Longitudinal Studies', 'Quality of Life', 'Regression Analysis', 'United Kingdom'] | 24,659,492 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.85... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Acute renal failure independently predicts mortality after myeloablative allogeneic hematopoietic cell transplant. | BACKGROUND: Patients undergoing myeloablative allogeneic hematopoietic cell transplantation (HCT) have a high incidence of acute renal failure (ARF). However, it is unclear if ARF is independently associated with mortality after this procedure.METHODS: We performed meta-analysis of published reports on ARF after myeloa... | ['Acute Kidney Injury', 'Adult', 'Aged', 'Cohort Studies', 'Colorado', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Middle Aged', 'Risk Factors', 'Transplantation, Homologous'] | 15,840,050 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.107.567.875.760.210'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'],... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
O-GlcNAc modification of the runt-related transcription factor 2 (Runx2) links osteogenesis and nutrient metabolism in bone marrow mesenchymal stem cells. | Runx2 is the master switch controlling osteoblast differentiation and formation of the mineralized skeleton. The post-translational modification of Runx2 by phosphorylation, ubiquitinylation, and acetylation modulates its activity, stability, and interactions with transcriptional co-regulators and chromatin remodeling ... | ['Acetylglucosamine', 'Adaptor Proteins, Signal Transducing', 'Animals', 'Arginine', 'Bone Marrow Cells', 'Bone Morphogenetic Protein 2', 'Bone Morphogenetic Protein 7', 'Cell Differentiation', 'Cell Line', 'Core Binding Factor Alpha 1 Subunit', 'Enzyme Inhibitors', 'HEK293 Cells', 'Humans', 'Membrane Proteins', 'Mesen... | 25,187,572 | [['D09.067.342.531.050'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A11.148', 'A15.378.316'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['D12.644.276.954.200.700', 'D12.776.467.942.200.700', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hexadecylphosphocholine inhibits phosphatidylinositol and phosphatidylcholine phospholipase C in human leukemia cells. | Hexadecylphosphocholine (HePC) is the main representative of a new group of antineoplastic agents, the alkylphosphocholines. Besides remarkable antiproliferative properties on tumor cells in vitro and in vivo, HePC also induces differentiation and inhibits invasive growth of neoplastic cells. Knowledge of the molecular... | ['Antineoplastic Agents', 'Cell Membrane', 'Cells, Cultured', 'Chromatography, Thin Layer', 'Enzyme Activation', 'Humans', 'Leukemia', 'N-Formylmethionine Leucyl-Phenylalanine', 'Phosphatidylinositol Diacylglycerol-Lyase', 'Phosphorylcholine', 'Tumor Necrosis Factor-alpha', 'Type C Phospholipases'] | 9,414,418 | [['D27.505.954.248'], ['A11.284.149'], ['A11.251'], ['E05.196.181.400.537'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['D02.886.030.676.450.440', 'D12.125.072.050.685.445', 'D12.125.142.666.500', 'D12.125.166.676.450.440', 'D12.644.456.400', 'D23.125.685'], ['D08.811... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhalable nanoparticles, a non-invasive approach to treat lung cancer in a mouse model. | Doxorubicin-loaded nanoparticles (NPs) were incorporated into inhalable effervescent and non-effervescent carrier particles using a spray-freeze drying technique. The prepared inhalable powders were tested in a tumor bearing Balb/c mouse model. Control mice were treated with blank inhalable NPs, inhalable lactose powde... | ['Administration, Inhalation', 'Animals', 'Antibiotics, Antineoplastic', 'Carcinoma, Non-Small-Cell Lung', 'Doxorubicin', 'Drug Carriers', 'Female', 'Humans', 'Lung', 'Lung Neoplasms', 'Mice', 'Mice, Inbred BALB C', 'Nanoparticles'] | 21,059,378 | [['E02.319.267.050'], ['B01.050'], ['D27.505.954.248.106'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D26.255.260', 'E02.319.300.380'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. | The heart responds to stress signals by hypertrophic growth, which is accompanied by activation of the MEF2 transcription factor and reprogramming of cardiac gene expression. We show here that class II histone deacetylases (HDACs), which repress MEF2 activity, are substrates for a stress-responsive kinase specific for ... | ['Aging', 'Animals', 'Calcineurin', 'Calcium-Calmodulin-Dependent Protein Kinase Type 1', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cardiomegaly', 'Carrier Proteins', 'DNA-Binding Proteins', 'Enzyme Inhibitors', 'Gene Expression Regulation, Developmental', 'Heart', 'Histone Deacetylase 2', 'Histone Deacetylases'... | 12,202,037 | [['G07.345.124'], ['B01.050'], ['D08.811.277.352.650.625.150', 'D12.644.360.087', 'D12.776.476.087'], ['D08.811.913.696.620.682.700.125.100', 'D12.644.360.100.100', 'D12.776.476.100.100'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['C14.280.195', 'C23.300.775.250'], ['D12.776.157'], ['D... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Who, What, How much, Where? - an analysis of publications by German authors on sociopsychiatric issues in scientific journals]. | OBJECTIVE: Stimulated by Finzen's critical appraisal of the actual situation of social psychiatric research in Germany an analysis of recent publications of German authors on social psychiatric topics was carried out.METHOD: Covering the years 1998 - 2000, 70 scientific journals from psychiatry and related disciplines ... | ['Authorship', 'Community Psychiatry', 'Germany', 'Humans', 'Periodicals as Topic', 'Publishing', 'Research'] | 11,721,222 | [['L01.559.423.906.215'], ['F04.096.544.215', 'H02.403.690.150'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682.829.678'], ['L01.737'], ['H01.770.644']] | ['Information Science [L]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
Parametric Response Mapping of Bronchiolitis Obliterans Syndrome Progression After Lung Transplantation. | Bronchiolitis obliterans syndrome (BOS) remains a major complication after lung transplantation. Air trapping and mosaic attenuation are typical radiological features of BOS; however, quantitative evaluation remains troublesome. We evaluated parametric response mapping (PRM, voxel-to-voxel comparison of inspiratory and... | ['Adult', 'Bronchiolitis Obliterans', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Forced Expiratory Volume', 'Graft Rejection', 'Humans', 'Lung Transplantation', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Syndrome', 'Tomography, X-Ray Computed'] | 27,367,568 | [['M01.060.116'], ['C08.127.446.135.140', 'C08.381.495.146.135.140'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.928.600.495', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thio-derived disulfides as potent inhibitors of botulinum neurotoxin type B: implications for zinc interaction. | Botulinum neurotoxin type B causes the inhibition of acetylcholine release at the neuromuscular junction resulting in a flaccid paralysis designated botulism. This occurs through the cleavage of synaptobrevin, an intracellular critical component of neurotransmitter exocytosis, by the zinc-metallopeptidase activity of t... | ['Binding Sites', 'Botulinum Toxins', 'Botulinum Toxins, Type A', 'Calcium-Binding Proteins', 'Disulfides', 'Enzyme Inhibitors', 'Humans', 'Membrane Glycoproteins', 'Nerve Tissue Proteins', 'Sulfur Compounds', 'Synaptotagmins', 'Zinc'] | 14,527,562 | [['G02.111.570.120'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['D12.776.157.125'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.8... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of hydroxyapatite on the biodegradation and biomechanical stability of polyester nanocomposites for orthopaedic applications. | The effect of hydroxyapatite (HAP) on the performance of nanocomposites of an unsaturated polyester, i.e., hydroxy-terminated high molecular weight poly(proplyene fumarate) (HT-PPFhm), was investigated. A thermoset nanocomposite was prepared with nanoparticles of calcined HAP (<100 nm, rod-like shape, filler content 30... | ['Absorbable Implants', 'Animals', 'Bone Substitutes', 'Durapatite', 'Elastic Modulus', 'Femoral Fractures', 'Fumarates', 'Hardness', 'Materials Testing', 'Nanostructures', 'Orthopedic Equipment', 'Polypropylenes', 'Rabbits', 'Treatment Outcome'] | 19,788,944 | [['E07.695.025'], ['B01.050'], ['D25.130.325', 'J01.637.051.130.325'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['G01.374.590.605'], ['C26.404.061', 'C26.558.276'], ['D02.241.081.337.302'], ['G01.374.647'], ['E05.570'], ['J01.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A novel delta opioid receptor antagonist, SoRI-9409, produces a selective and long-lasting decrease in ethanol consumption in heavy-drinking rats. | BACKGROUND: Naltrexone, a compound with high affinity for the mu opioid receptor (MOP-R) reduces alcohol consumption. SoRI-9409 is a derivative of naltrexone that has highest affinity at delta opioid receptors (DOP-Rs). We have investigated the effects of SoRI-9409 on ethanol consumption to determine the consequences o... | ['Alcohol Drinking', 'Alcoholism', 'Animals', 'Behavior, Animal', 'Brain', 'Choice Behavior', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Ethanol', 'Food Preferences', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Male', 'Morphine Derivatives', 'Naloxone', 'Narcotic Antagonists', 'Narcotics', 'Protein Bind... | 18,774,553 | [['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['B01.050'], ['F01.145.113'], ['A08.186.211'], ['F02.463.785.373.346'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.375'], ['F01.145.407.516', 'G07.203.650.353.516'], ['D02.886.765.380', 'D13.695.667.454.5... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Viewpoint-dependent representation of contextual information in visual working memory. | Objects are not represented individually in visual working memory (VWM), but in relation to the contextual information provided by other memorized objects. We studied whether the contextual information provided by the spatial configuration of all memorized objects is viewpoint-dependent. We ran two experiments asking p... | ['Data Display', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Pattern Recognition, Visual', 'Reaction Time', 'Space Perception', 'User-Computer Interface', 'Video Games'] | 24,470,259 | [['F02.784.412.221', 'L01.296'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.778'], ['L01.224.900.910'], ['I03.450.642.693.930', 'L01.224.900.930']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Indirect sandwich enzyme-linked immunosorbent assay for rapid detection of Streptococcus pneumoniae type 3 antigen. | An indirect sandwich enzyme-linked immunosorbent assay for the detection of the polysaccharide antigen of type 3 pneumococcus (SSS-III) is reported. Polystyrene balls with attached anti-SSS-III antibody serve as the solid phase, and antigen is detected using an alkaline phosphatase-labeled antiglobulin conjugate. The r... | ['Antigens, Bacterial', 'Cross Reactions', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoenzyme Techniques', 'Pneumococcal Infections', 'Streptococcus pneumoniae'] | 7,000,815 | [['D23.050.161'], ['G12.122.281'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['C01.150.252.410.890.670'], ['B03.353.750.737.872.550', 'B0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delayed pain decrease following M1 tDCS in spinal cord injury: A randomized controlled clinical trial. | Despite some encouraging findings for the treatment of neuropathic pain in patients with spinal cord injury (SCI), transcranial direct current stimulation (tDCS) directed to the primary motor cortex (M1) has faced some mixed results. Prior to translating this technology to clinical care, consistent results and durable ... | ['Follow-Up Studies', 'Humans', 'Motor Cortex', 'Neuralgia', 'Pain Management', 'Pain Measurement', 'Quality of Life', 'Spinal Cord Injuries', 'Transcranial Direct Current Stimulation'] | 28,822,837 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['C10.668.829.600', 'C23.888.592.612.664'], ['E02.745', 'N04.590.607.500'], ['E01.370.600.550.324']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Ly49Q defines 2 pDC subsets in mice. | Plasmacytoid dendritic cells (pDCs) play an important primary role for antiviral innate immunity by rapidly producing large amounts of type 1 interferon (IFN) upon viral infection. To study pDC biology, we generated a monoclonal antibody, termed 2E6, that recognizes pDCs. Molecular cloning of a cDNA encoding the 2E6 an... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Antigens, Ly', 'Biomarkers', 'Bone Marrow Cells', 'CD11b Antigen', 'CD11c Antigen', 'Cells, Cultured', 'Cloning, Molecular', 'DNA, Complementary', 'Dendritic Cells', 'Female', 'Interferon-alpha', 'Lectins, C-Type', 'Leukocyte Common A... | 15,598,811 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['D23.050.301.264.920', 'D23.101.100.920'], ['D23.101'], ['A11.148', 'A15.378.316'], ['D12.776.395.550.200.074.750', 'D12.776.543.550.200.093.750', 'D12.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Gastric gnathostomiasis in a cat. | A mass found in the stomach of a 10-year old cat contained a female worm of the genus Gnathostoma. The mass was described as a muscular pseudogranuloma induced by the worm. Although the worm species could not be ascertained, it was concluded that the cat served as an aberrant host for a Gnathostoma sp that usually infe... | ['Animals', 'Cat Diseases', 'Cats', 'Female', 'Gnathostoma', 'Nematode Infections', 'Stomach Diseases'] | 3,610,757 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.500.500.294.400.937.700.722.375'], ['C01.610.335.508'], ['C06.405.748']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subcellular distribution of small GTP binding proteins in pancreas: identification of small GTP binding proteins in the rough endoplasmic reticulum. | Subfractionation of a canine pancreatic homogenate was performed by several differential centrifugation steps, which gave rise to fractions with distinct marker profiles. Specific binding of guanosine 5'-[gamma-[35S]thio]triphosphate (GTP[gamma-35S]) was assayed in each fraction. Enrichment of GTP[gamma-35S] binding wa... | ['Animals', 'Cell Fractionation', 'Centrifugation, Density Gradient', 'Dogs', 'Endoplasmic Reticulum', 'GTP-Binding Proteins', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Guanosine Triphosphate', 'Microscopy, Electron', 'Microsomes', 'Pancreas', 'Subcellular Fractions', 'Thionucleotides'] | 2,106,133 | [['B01.050'], ['E05.242.251'], ['E05.181.724.336', 'E05.196.941.336'], ['B01.050.150.900.649.313.750.250.216.200'], ['A11.284.430.214.190.875.248'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D02.886.765.380', 'D13.695.667.454.504.380', 'D13.695.827.426.504.380', 'D13.695.900.380'], ['D03.633.100.759.646.454.504... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of reference GFR in a development population: a critical factor for the establishment of a GFR estimation equation. | BACKGROUND AND AIM: Our previous work showed that the performance of MDRD equations could be improved by modifying the original MDRD equation. However, during the modification we recognized that reference GFR (rGFR) distribution was not similar between the MDRD study and the Chinese Estimating GFR (eGFR) Investigation ... | ['Biomarkers', 'China', 'Creatinine', 'Demography', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Reference Values'] | 21,955,865 | [['D23.101'], ['Z01.252.474.164'], ['D03.383.129.308.207'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E05.978.810']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Use of the microprojector MRTU 42-2216-63 for microphotography]. | Two methods of microphotography using microprojector MPTY 42-2216-63 without using microphoto heads are proposed. In the first method, a mirror camera without objective is introduced perpendicularly to the luminous flux going from the microprojector ocular to the vertical screen. Exposure time is determined with any ph... | ['Histology', 'Photomicrography'] | 7,417,007 | [['H01.158.100.656'], ['E01.370.350.515.799', 'E01.370.350.600.635', 'E05.595.799']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cadmium, lead and mercury levels in feeding yeast produced in Czechoslovakia. | Ninety-six samples of the feeding yeast known as VITEX were analyzed for Cd, Pb and Hg content during 1987-1989. Cadmium content ranged from 0.30 to 5.12 mg/kg(-1), lead content from 0.21 to 3.01 mg/kg(-1) and mercury content from 0.008 to 0.187 mg/kg(-1). Our findings meet the current government standards (max. allowe... | ['Animal Feed', 'Animals', 'Cadmium', 'Czechoslovakia', 'Lead', 'Mercury', 'Spectrophotometry, Atomic', 'Yeasts'] | 1,594,924 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['Z01.586.250'], ['D01.268.556.435', 'D01.552.544.435'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['E05.196.712.726.551', 'E05.196.867.826.551'], ['B01.300.930']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
A modified staining method for connective tissue in semi-thin histological sections of peripheral and cranial nerves. | A simple staining method for collagen in semi-thin sections of nerves is described. This technique consists of applying basic fuchsin (0.05%) solution for 2 min. to +/- 1.25 microns plastic resin-embedded sections after routine toluidine blue staining. This staining method clearly demonstrates the amount and orientatio... | ['Animals', 'Collagen', 'Coloring Agents', 'Connective Tissue', 'Cranial Nerves', 'Microtomy', 'Peripheral Nerves', 'Plastic Embedding', 'Rats', 'Rosaniline Dyes', 'Tolonium Chloride'] | 10,743,716 | [['B01.050'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D27.720.233'], ['A10.165'], ['A08.800.800.120'], ['E01.370.225.500.620.530', 'E01.370.225.750.600.530', 'E05.200.500.620.530', 'E05.200.750.600.530'], ['A08.800.800'], ['E01.370.225.500.620.760.440.640', 'E01.370.225.750.600.760.440.640', 'E05.200.500.620.760.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of melatonin on luteinizing hormone secretion in anestrous ewes following dopamine and opiate receptor blockade. | In the present investigation we have examined the ability of melatonin to modify the pulsatile LH secretion induced by treatment with a DA antagonist (sulpiride, SULP) or opioid antagonist (naloxone, NAL) in intact mid-anestrous ewes. The experimental design comprised the following treatments-in experiment 1: (1) intra... | ['Anestrus', 'Animals', 'Cerebral Ventricles', 'Dopamine Antagonists', 'Female', 'Luteinizing Hormone', 'Melatonin', 'Naloxone', 'Narcotic Antagonists', 'Periodicity', 'Photoperiod', 'Sheep', 'Sulpiride'] | 14,998,651 | [['G08.686.195.249'], ['B01.050'], ['A08.186.211.140'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['D03.633.100.473.914.481', 'D06.472.506'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04.61... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In Situ Localization of Ribosomal Sites in Peckoltia and Ancistomus (Loricariidae: Hypostominae) from the Amazon Basin. | Loricariidae is a diverse group of fish from the neotropical region, occupying a wide variety of freshwater environments. Cytogenetic data have brought important insights into Loricariidae diversity because they help validate undescribed species as well as our understanding of inter- and intraspecific diversity. Howeve... | ['Animals', 'Brazil', 'Catfishes', 'Cytogenetics', 'DNA, Ribosomal', 'Genetic Variation', 'Karyotyping', 'RNA, Ribosomal, 18S', 'RNA, Ribosomal, 5S'] | 29,420,137 | [['B01.050'], ['Z01.107.757.176'], ['B01.050.150.900.493.080'], ['H01.158.273.343.180'], ['D13.444.308.475'], ['G05.365'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['D13.444.735.686.675'], ['D13.444.735.686.650']] | ['Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
The components of rice and watermelon root exudates and their effects on pathogenic fungus and watermelon defense. | Watermelon (Citrullus lanatus) is susceptible to wilt disease caused by the fungus Fusarium oxysporum f. sp niveum (FON). Intercropping management of watermelon/aerobic rice (Oryza sativa) alleviates watermelon wilt disease, because some unidentified component(s) in rice root exudates suppress FON sporulation and spore... | ['Chitinases', 'Citrullus', 'Disease Resistance', 'Fusarium', 'Gene Expression Regulation, Plant', 'Glucan 1,3-beta-Glucosidase', 'Hydroxybenzoates', 'Oryza', 'Plant Diseases', 'Plant Exudates', 'Plant Leaves', 'Plant Proteins', 'Plant Roots', 'Real-Time Polymerase Chain Reaction', 'Spores, Fungal'] | 27,217,091 | [['D08.811.277.450.207'], ['B01.650.940.800.575.912.250.300.140'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['B01.300.381.366'], ['G05.308.375'], ['D08.811.277.450.420.200.500'], ['D02.241.223.100.300', 'D02.241.511.390', 'D02.455.426.559.389.127.281', 'D02.455.426.559.389.657.410'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Experience with an implantable tiered therapy device incorporating antitachycardia pacing and cardioverter/defibrillator therapy. | The implantable cardioverter-defibrillator provides an alternative therapy for medically refractory ventricular tachyarrhythmias in patients who are not candidates for ventricular operations or in whom these operations have failed. Currently, however, available devices have limitations. In this report we describe our e... | ['Adolescent', 'Adult', 'Aged', 'Cardiac Pacing, Artificial', 'Defibrillators, Implantable', 'Electrophysiology', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Postoperative Period', 'Tachycardia, Ventricular'] | 8,445,925 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.331.200'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['H01.158.344.528', 'H01.158.782.236'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Rhabdomyolysis and acute renal failure caused by haloperidol-decanoate (neuroleptic malignant syndrome)]. | A case of rhabomyolysis with attendant severe acute renal failure, arisen in a 59-year-old male treated with haloperidol-decanoate, is presented. The patient has been affected by paranoia schizophrenia since childhood, and he was treated with electroshock and successively with neuroleptics p.o. Four years before our ob... | ['Acute Kidney Injury', 'Antipsychotic Agents', 'Haloperidol', 'Humans', 'Male', 'Middle Aged', 'Neuroleptic Malignant Syndrome', 'Rhabdomyolysis'] | 9,053,957 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D02.522.352.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.079.737', 'C10.720.737', 'C25.723.705.600'], ['C05.651.807']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation and characterization of the promoter for the gene coding for the 68 kDa carnitine palmitoyltransferase from the rat. | Carnitine palmitoyltransferase (CPT) regulates the flux of long-chain fatty acids into the mitochondria for subsequent beta-oxidation. A 485 bp segment of the promoter for the gene encoding the 68 kDa CPT was isolated from a rat lambda DASH genomic library using the polymerase chain reaction. The promoter contained a c... | ['Animals', 'Base Sequence', 'Carnitine O-Palmitoyltransferase', 'Cell Transformation, Viral', 'Chloramphenicol O-Acetyltransferase', 'DNA', 'DNA Fingerprinting', 'Genetic Vectors', 'Humans', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Promoter Regions, Genetic', 'Rats', 'Transcription Factors', 'Transcrip... | 1,417,736 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.050.350.200'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['D08.811.913.050.134.170'], ['D13.444.308'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['G05.360.337']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Absorption of arsenic from soil and water by two chard (Beta vulgaris L.) varieties: A potential risk to human health. | The accumulation of arsenic (As) in vegetables poses a risk of contamination to humans via the food chain. Two chard (var. cicla and var. d'ampuis) crops were grown for 60 days in greenhouses on Aridisol soil, and irrigated with water from Pastos Chicos, Jujuy (Argentina). The soil and water used in the trial presented... | ['Argentina', 'Arsenic', 'Beta vulgaris', 'Food Contamination', 'Humans', 'Soil', 'Soil Pollutants', 'Water'] | 29,665,483 | [['Z01.107.757.077'], ['D01.268.513.249'], ['B01.650.940.800.575.912.250.200.399'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756'], ['D01.045.250.875', 'D01.248.... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Increased risk of miscarriage among women experiencing physical or sexual intimate partner violence during pregnancy in Guatemala City, Guatemala: cross-sectional study. | BACKGROUND: Violence against women by their male intimate partners (IPV) during pregnancy may lead to negative pregnancy outcomes. We examined the role of IPV as a potential risk factor for miscarriage in Guatemala. Our objectives were: (1) To describe the magnitude and pattern of verbal, physical and sexual violence b... | ['Abortion, Spontaneous', 'Adolescent', 'Adult', 'Battered Women', 'Cross-Sectional Studies', 'Female', 'Guatemala', 'Humans', 'Interpersonal Relations', 'Maternal Welfare', 'Middle Aged', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Prenatal Care', 'Prevalence', 'Risk Factors', 'Socioeconomic Factors', 'Spouse... | 21,733,165 | [['C13.703.039', 'G08.686.784.769.496.125'], ['M01.060.057'], ['M01.060.116'], ['M01.975.155'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.107.169.454'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['I01.880.787.678'], ['M01.060.116.630'], ['G08.686.784.76... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Association of Baseline Prostate-Specific Antigen Level With Long-term Diagnosis of Clinically Significant Prostate Cancer Among Patients Aged 55 to 60 Years: A Secondary Analysis of a Cohort in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. | Importance: The use of prostate-specific antigen (PSA) screening for prostate cancer is controversial because of the risk of overdiagnosis and overtreatment of indolent cancers. Optimal screening strategies are highly sought.Objective: To estimate the long-term risk of any prostate cancer and clinically significant pro... | ['Aged', 'Follow-Up Studies', 'Humans', 'Incidence', 'Kallikreins', 'Kaplan-Meier Estimate', 'Male', 'Mass Screening', 'Middle Aged', 'Prospective Studies', 'Prostate-Specific Antigen', 'Prostatic Neoplasms'] | 31,940,039 | [['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['D08.811.277.656.300.760.442', 'D08.811.277... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Placental insufficiency as a possible cause of low maternal serum human chorionic gonadotropin and low maternal serum unconjugated estriol levels in triploidy. | We report three cases in which triploidy (69,XXX) was detected by amniocentesis performed for very low maternal serum human chorionic gonadotropin levels. All three cases also had low maternal serum unconjugated estriol levels. We suggest placental insufficiency as the cause of the very low human chorionic gonadotropin... | ['Abortion, Therapeutic', 'Adult', 'Amniocentesis', 'Chorionic Gonadotropin', 'Estriol', 'Female', 'Humans', 'Placental Insufficiency', 'Ploidies', 'Pregnancy'] | 1,530,036 | [['E04.520.050.060'], ['M01.060.116'], ['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D04.210.500.365.415.331', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of AnaeroGen system for growth of anaerobic bacteria. | The Oxoid AnaeroGen system was compared with the BBL GasPak for the production of an anaerobic atmosphere and was evaluated for its ability to support the growth of 135 clinically significant anaerobic bacteria. An anaerobe chamber was used as the "gold standard" for supporting the growth of anaerobes. The AnaeroGen re... | ['Atmosphere Exposure Chambers', 'Bacteria, Anaerobic', 'Bacteriological Techniques'] | 7,494,033 | [['E07.079'], ['B03.130'], ['E01.370.225.875.150', 'E05.200.875.150']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of fenprostalene 14 days after fertirelin treatment on intervals from treatment to conception in cows with follicular cysts diagnosed by milk progesterone test. | Of 170 cows with ovarian cysts which were detected by palpation of the ovaries per rectum, 88 cows (51.8%) were diagnosed as having follicular cysts on the basis of milk progesterone concentrations. Eighty-three of the 88 cows were used for treatment trials. A group of 56 cows injected subcutaneously with fenprostalene... | ['Abortifacient Agents, Nonsteroidal', 'Animals', 'Biomarkers', 'Cattle', 'Cattle Diseases', 'Clinical Trials as Topic', 'Drug Therapy, Combination', 'Estrus', 'Female', 'Gonadotropin-Releasing Hormone', 'Hormones', 'Milk', 'Ovarian Cysts', 'Ovarian Follicle', 'Pregnancy', 'Pregnancy, Animal', 'Progesterone', 'Prostagl... | 8,512,999 | [['D27.505.696.875.131.100', 'D27.505.954.705.131.100'], ['B01.050'], ['D23.101'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.319.310'], ['G08.686.195.500'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.45... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Cathepsin G: the significance in rheumatoid arthritis as a monocyte chemoattractant. | Human cathepsin G (EC 3.4.21.20) has been reported to have the in vitro chemotactic activity for human monocytes. In this study, we examined the role of cathepsin G in monocyte involvement in joint inflammation of rheumatoid arthritis (RA) as a monocyte chemoattractant. Eighteen patients with RA and four patients with ... | ['Arthritis, Rheumatoid', 'Cathepsin G', 'Cathepsins', 'Chemotactic Factors', 'Female', 'Humans', 'Immunohistochemistry', 'Inflammation', 'Macrophages', 'Male', 'Middle Aged', 'Monocytes', 'Serine Endopeptidases', 'Synovial Fluid', 'Synovial Membrane'] | 16,977,463 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D08.811.277.656.224.350', 'D08.811.277.656.300.760.066', 'D08.811.277.656.959.350.066'], ['D08.811.277.656.224'], ['D23.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular basis for a severe case of leukocyte adhesion deficiency. | The leukocyte integrins LFA-1, Mac-1 and p150,95 (CD11a/CD18, CD11b/CD18, CD11c/CD18) mediate crucial leukocyte adhesive functions in immune and inflammatory reactions. Leukocyte adhesion deficiency (LAD) disease is caused by the defective expression of these adhesion molecules on leukocytes, and is characterized by re... | ['Amino Acid Sequence', 'Antigens, CD', 'CD11 Antigens', 'CD18 Antigens', 'Child, Preschool', 'Female', 'Humans', 'Leukocytes', 'Lymphocyte Function-Associated Antigen-1', 'Macrophage-1 Antigen', 'Molecular Sequence Data', 'RNA, Messenger'] | 1,352,501 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D12.776.395.550.200.074', 'D12.776.543.550.200.093', 'D23.050.301.350.074'], ['D12.776.395.550.200.275.750', 'D12.776.543.550.200.275.750', 'D12.776.543.750.705.408.200.249', 'D12.776.543.750.705.408.600.100.750', 'D12.776.543.75... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Corynebacterium glutamicum utilizes both transsulfuration and direct sulfhydrylation pathways for methionine biosynthesis. | A direct sulfhydrylation pathway for methionine biosynthesis in Corynebacterium glutamicum was found. The pathway was catalyzed by metY encoding O-acetylhomoserine sulfhydrylase. The gene metY, located immediately upstream of metA, was found to encode a protein of 437 amino acids with a deduced molecular mass of 46,751... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Carbon-Oxygen Lyases', 'Cloning, Molecular', 'Corynebacterium', 'Cysteine Synthase', 'Gene Expression Regulation, Bacterial', 'Methionine', 'Molecular Sequence Data', 'Multienzyme Complexes', 'Saccharomyces cerevisiae Proteins', 'Sequence Alignment', 'Sequ... | 11,844,756 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.520.241'], ['E05.393.220'], ['B03.510.024.250', 'B03.510.460.400.400.200'], ['D08.811.913.225.224'], ['G05.308.300'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Paediatric patients seen in 18 emergency departments during the COVID-19 pandemic. | BACKGROUND: Public health mitigation strategies in British Columbia during the pandemic included stay-at-home orders and closure of non-essential services. While most primary physicians' offices were closed, hospitals prepared for a pandemic surge and emergency departments (EDs) stayed open to provide care for urgent n... | ['Adolescent', 'Betacoronavirus', 'British Columbia', 'COVID-19', 'Child', 'Child, Preschool', 'Coronavirus Infections', 'Emergencies', 'Emergency Medicine', 'Emergency Service, Hospital', 'Female', 'Health Services Accessibility', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Pandemics', 'Pat... | 33,127,743 | [['M01.060.057'], ['B04.820.578.500.540.150.113'], ['Z01.107.567.176.160'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['M01.060.406'], ['M01.060.406.448'], ['C01.925.782.600.550.200'], ['C23.550.291.781', 'N06.2... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Interrelation between the renal sympathetic nerve and atrial natriuretic peptide in conscious long Evans rats subjected to sodium restriction. | The renal excretory function and plasma renin activity (PRA) were studied in conscious rats on a low sodium diet (25 mmol/kg) after atrial natriuretic peptide (ANP) infusion (100 ng/kg b.w./min) for 80 min through a catheter implanted in the right atrium. The half of the animals were with bilateral kidney denervation. ... | ['Animals', 'Atrial Natriuretic Factor', 'Denervation', 'Diabetes Mellitus, Experimental', 'Diet, Sodium-Restricted', 'Glomerular Filtration Rate', 'Injections, Intravenous', 'Kidney', 'Male', 'Norepinephrine', 'Osmolar Concentration', 'Rats', 'Rats, Brattleboro', 'Renin', 'Sympathetic Nervous System'] | 7,645,406 | [['B01.050'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E04.525.210'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['E02.642.249.290', 'G07.203.650.240.290'], ['E01.370.390.400.300', 'G08.852.357'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['A05.810.453'], ['D02.033.100.291.502', 'D02.092.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of miR-21 by Ghrelin Ameliorates Ischemia/Reperfusion-Induced Acute Kidney Injury by Inhibiting Inflammation and Cell Apoptosis. | Renal ischemia-reperfusion (I/R) injury can be caused by cardiac surgery, renal vascular obstruction, and kidney transplantation, mainly leading to acute kidney injury (AKI), which is complicated by lack of effective preventative and therapeutic strategies. Ghrelin has recently been reported to possess anti-inflammator... | ['Acute Kidney Injury', 'Animals', 'Apoptosis', 'Cell Line', 'Creatinine', 'Epithelial Cells', 'Gene Expression Regulation', 'Ghrelin', 'Inflammation', 'Kidney Function Tests', 'Kidney Tubules', 'Male', 'MicroRNAs', 'Phosphatidylinositol 3-Kinases', 'Proto-Oncogene Proteins c-akt', 'Rats', 'Rats, Sprague-Dawley', 'Repe... | 27,152,763 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['B01.050'], ['G04.146.954.035'], ['A11.251.210'], ['D03.383.129.308.207'], ['A11.436'], ['G05.308'], ['D06.472.699.301', 'D12.644.548.322'], ['C23.550.470'], ['E01.370.390.400'], ['A05.810.453.736.560'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.55... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organization and evolution of the chalcone synthase gene family in bread wheat and relative species. | BACKGROUND: Flavonoid compounds are secondary plant metabolites, having a functional importance in plant development, protection from pathogens and unfavorable environmental factors. Chalcone synthase (CHS) is a key enzyme in the biosynthesis of flavonoids; it is involved in biosynthesis of all classes of flavonoid com... | ['Acyltransferases', 'Flavonoids', 'Models, Molecular', 'Multigene Family', 'Phylogeny', 'Triticum'] | 30,885,129 | [['D08.811.913.050'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['E05.599.595'], ['G05.360.340.024.340.645'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.650.940.800.575.912.250.822.918']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In situ observation of the Cardinium symbionts of Brevipalpus (Acari: Tenuipalpidae) by electron microscopy. | Brevipalpus (Acari: Tenuipalpidae) mites are important pests on a variety of host plant species. The mites damage their hosts directly by feeding and some species also serve as vectors of plant viruses. Among more than 200 described Brevipalpus species, three are recognized as vectors of plant viruses: B. phoenicis, B.... | ['Animals', 'Cytophagaceae', 'Female', 'Life Cycle Stages', 'Microscopy, Electron, Transmission', 'Mites', 'Ovum', 'Polymerase Chain Reaction', 'Symbiosis'] | 17,634,867 | [['B01.050'], ['B03.440.080.130', 'B03.440.400.425.300'], ['B05.500', 'G07.345.500.550.500'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['B01.050.500.131.166.132.419'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['E05.393.620.500'], ['G06.550.800', 'G16.840']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of the effects of neuroleptics on phencyclidine-induced behaviors in the rat. | The dose-response effects of neuroleptic pretreatment on phencyclidine (PCP; 3 or 5 mg/kg)-induced locomotor activity, stereotyped behaviors and ataxia were quantified in groups of male rats using rating scales recently developed in this laboratory. Three butyrophenone neuroleptics consistently produced dose-dependent ... | ['Animals', 'Antipsychotic Agents', 'Ataxia', 'Behavior, Animal', 'Dose-Response Relationship, Drug', 'Humans', 'Male', 'Motor Activity', 'Phencyclidine', 'Rats', 'Rats, Inbred Strains', 'Stereotyped Behavior'] | 6,119,221 | [['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['C10.597.350.090', 'C23.888.592.350.090'], ['F01.145.113'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['D03.383.621.699'], ['B01.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
myo-Inositol binding and transport in brush border membranes of rat kidney. | Using hypotonically treated brush border membranes, binding and transport of myo-inositol were examined. By hypotonic treatment, both total and non-specific uptake decreased significantly, but specific uptake was not affected. myo-Inositol release from membranes preloaded by incubation for 2 min was very rapid and abou... | ['Animals', 'Biological Transport', 'Cell Membrane', 'Inositol', 'Kidney', 'Kinetics', 'Mannitol', 'Osmolar Concentration', 'Potassium', 'Rats', 'Sodium'] | 831,786 | [['B01.050'], ['G03.143'], ['A11.284.149'], ['D02.033.800.519', 'D09.853.519'], ['A05.810.453'], ['G01.374.661', 'G02.111.490'], ['D02.033.800.609', 'D09.853.609'], ['G02.640'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.268.549.750',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis | The optrA gene, which confers transferable resistance to oxazolidinones and phenicols, is defined as an ATP-binding cassette (ABC) transporter but lacks transmembrane domains. The resistance mechanism of optrA and whether it involves antibiotic efflux or ribosomal protection remain unclear. In this study, we determined... | ['Drug Resistance, Bacterial', 'Enterococcus faecalis', 'Linezolid', 'Oxazolidinones', 'Species Specificity', 'Staphylococcus aureus', 'Thiamphenicol'] | 30,518,106 | [['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['D02.065.064.463', 'D02.241.081.018.110.525', 'D03.383.129.462.600.550'], ['D03.383.129.462.600'], ['G16.824'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Injury risk in professional basketball players: a comparison of Women's National Basketball Association and National Basketball Association athletes. | BACKGROUND: Gender-based differences in injury rates have been reported in scholastic and collegiate basketball. The purpose of this study was to retrospectively compare injury rates in women's and men's professional basketball.HYPOTHESIS: Female professional basketball players are injured at a higher rate than are men... | ['Adult', 'Athletic Injuries', 'Basketball', 'Female', 'Humans', 'Incidence', 'Male', 'Retrospective Studies', 'Sex Distribution'] | 16,493,173 | [['M01.060.116'], ['C26.115'], ['I03.450.642.845.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.33... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Serum sclerostin and DKK1 in relation to exercise against bone loss in experimental bed rest. | The impact of effective exercise against bone loss during experimental bed rest appears to be associated with increases in bone formation rather than reductions of bone resorption. Sclerostin and dickkopf-1 are important inhibitors of osteoblast activity. We hypothesized that exercise in bed rest would prevent increase... | ['Adaptor Proteins, Signal Transducing', 'Adult', 'Bed Rest', 'Biomarkers', 'Bone Density', 'Bone Morphogenetic Proteins', 'Exercise', 'Femur', 'Genetic Markers', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Male', 'Osteogenesis', 'Time Factors'] | 26,056,021 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.116'], ['E02.075'], ['D23.101'], ['G11.427.100'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['G11.427.410.698.277', 'I03.350'], ['A02.835.232.043.150'], ['D23.101.387', 'G05.695.450'], ['B01.050.150.900.649.313.988.400.112.40... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
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