Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Community perspectives on drug/alcohol use, concerns, needs, and resources in four Washington State Tribal communities. | Community-university teams investigated substance use, abuse, and dependence (SUAD) and related concerns, needs, strengths, and resources in four Washington State Tribal communities. A total of 153 key community members shared their perspectives through 43 semi-structured interviews and 19 semi-structured focus groups.... | ['Alcohol-Related Disorders', 'Attitude to Health', 'Female', 'Focus Groups', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Humans', 'Indians, North American', 'Male', 'Opioid-Related Disorders', 'Prescription Drug Misuse', 'Substance-Related Disorders', 'Washington'] | 25,560,464 | [['C25.775.100', 'F03.900.100'], ['F01.100.150', 'N05.300.150'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['C25.775.643.500', 'F03.900.647.500'], ['... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Diode laser enucleation of the prostate (Dilep): technique and initial results]. | INTRODUCTION: we present our preliminary experience and results of practising the prostate enucleation technique using a diode laser (DiLEP) and intravesical morcellation, following the same principles of holmium laser enucleation (HoLEP).MATERIALS AND METHOD: we endoscopically treated benign prostate hyperplasia with ... | ['Aged', 'Aged, 80 and over', 'Humans', 'Lasers, Semiconductor', 'Male', 'Middle Aged', 'Prostatectomy', 'Prostatic Hyperplasia'] | 21,256,393 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490.480', 'E07.710.520.480'], ['M01.060.116.630'], ['E04.950.774.860.625'], ['C12.294.565.500']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential gene expression between developing queens and workers in the honey bee, Apis mellifera. | Many insects show polyphenisms, or alternative morphologies, which are based on differential gene expression rather than genetic polymorphism. Queens and workers are alternative forms of the adult female honey bee and represent one of the best known examples of insect polyphenism. Hormonal regulation of caste determina... | ['Animals', 'Bees', 'Cloning, Molecular', 'Crystallins', 'Evolution, Molecular', 'Gene Expression Regulation, Developmental', 'Genes, Insect', 'Insect Proteins', 'Larva', 'Molecular Sequence Data', 'Morphogenesis', 'Oncogene Proteins', 'Oxidoreductases', 'Proto-Oncogene Proteins c-ets', 'RNA, Messenger', 'Receptors, Re... | 10,318,926 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['E05.393.220'], ['D12.776.306.366'], ['G05.045.250', 'G16.075.250'], ['G05.308.310'], ['G05.360.340.024.340.340', 'G05.360.340.357.500'], ['D12.776.093.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['L01.453.245.667'], ['G07.345.500'], ['D12.776.624.664']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Relationship of protein molecular structure to metabolisable proteins in different types of dried distillers grains with solubles: a novel approach. | To date, there has been no study of protein molecular structures affected by bioethanol processing in relation to protein nutritive values of the new co-products of bioethanol production. The objective of the present study was to investigate the relationship between protein molecular structures (in terms of protein á-h... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Biofuels', 'Cattle', 'Diet', 'Dietary Proteins', 'Fermentation', 'Protein Conformation', 'Protein Denaturation', 'Triticum', 'Zea mays'] | 20,594,396 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['D20.147', 'N06.230.132.644.124'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G02.111.158.249', 'G03.191.249'], ['G02.111.570.820.709'], ['G01.154.651.750.500', 'G02.11... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Facile synthesis of bimetallic nanoplates consisting of Pd cores and Pt shells through seeded epitaxial growth. | Pd-Pt core-shell nanoplates with hexagonal and triangular shapes were synthesized through the heterogeneous, epitaxial growth of Pt on Pd nanoplates. The Pd nanoplates were synthesized by reducing Na2PdCl4 precursor with PVP as a reducing agent, which then served as seeds for the nucleation of Pt atoms formed by reduci... | ['Furans', 'Microscopy, Electron, Scanning', 'Microscopy, Electron, Transmission', 'Nanostructures', 'Palladium', 'Platinum'] | 18,616,327 | [['D03.383.312'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['J01.637.512'], ['D01.268.556.680', 'D01.268.956.718', 'D01.552.544.680'], ['D01.268.556.690', 'D01.268.956.734', 'D01.552.544.690']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Endarterectomy for calcified porcelain aorta associated with aortic valve stenosis. | BACKGROUND: A calcified porcelain aorta may complicate aortic valve insertion and require an alternative, more complex method for valve replacement. The reason for this is that sutures cannot be inserted through the calcific plates in the annulus and ascending aorta.METHODS: In 6 patients with an average age of 73.8 ye... | ['Aged', 'Aged, 80 and over', 'Aortic Diseases', 'Aortic Valve', 'Aortic Valve Stenosis', 'Calcinosis', 'Coronary Artery Bypass', 'Endarterectomy', 'Female', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Postoperative Complications', 'Radiography'] | 8,561,542 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.109'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['C18.452.174.130'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E04.100.814.456'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.76... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of Early Life Antibiotic Exposure and Neonatal Hyperoxia on the Murine Microbiome and Lung Injury. | Cross talk between the intestinal microbiome and the lung and its role in lung health remains unknown. Perinatal exposure to antibiotics disrupts the neonatal microbiome and may have an impact on the preterm lung. We hypothesized that perinatal antibiotic exposure leads to long-term intestinal dysbiosis and increased a... | ['Ampicillin', 'Animals', 'Animals, Newborn', 'Anti-Bacterial Agents', 'Bronchopulmonary Dysplasia', 'Disease Models, Animal', 'Dysbiosis', 'Female', 'Gastrointestinal Microbiome', 'Hyperoxia', 'Mice', 'Mice, Inbred C57BL', 'Pregnancy', 'Pulmonary Alveoli', 'RNA, Ribosomal, 16S'] | 31,628,395 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['B01.050'], ['B01.050.050.282'], ['D27.505.954.122.085'], ['C08.381.520.750.500', 'C16.614.521.125'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.308'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sensitive quantitative detection of Ralstonia solanacearum in soil by the most probable number-polymerase chain reaction (MPN-PCR) method. | We developed a sensitive quantitative assay for detecting Ralstonia solanacearum in soil by most probable number (MPN) analysis based on bio-PCR results. For development of the detection method, we optimized an elution buffer containing 5 g/L skim milk for extracting bacteria from soil and reducing contamination of pol... | ['Bacterial Load', 'Bacteriological Techniques', 'Polymerase Chain Reaction', 'Ralstonia solanacearum', 'Sensitivity and Specificity', 'Soil Microbiology', 'Temperature', 'Time Factors'] | 24,584,461 | [['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E05.393.620.500'], ['B03.660.075.090.688.600.750'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Lymphocyte activation, iron uptake and release by human mononuclear leukocytes in the presence of desferrioxamine. | Desferrioxamine (DFO), an iron chelating drug, has been shown to inhibit the proliferative response of leukocytes to mitogen. In the present study we investigated the effect of DFO on different aspects of human mononuclear leukocyte (MNL) function in vitro. DFO, added at the beginning of the culture period, inhibited b... | ['Deferoxamine', 'Humans', 'In Vitro Techniques', 'Iron', 'Leukocytes, Mononuclear', 'Lymphocyte Activation', 'Transferrin'] | 3,171,105 | [['D02.092.570.394.265', 'D02.241.511.372.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The majority of clathrin coated vesicles from lactating rabbit mammary gland arises from the secretory pathway. | Clathrin coated vesicles were isolated from lactating rabbit mammary gland by differential centrifugation, centrifugation on (2)H2O-sucrose cushions and Sephacryl S-1000 chromatography. Mammary epithelial cells contain an unexpectedly high quantity of clathrin coated vesicles which appear heterogeneous in size, with a ... | ['Adaptor Protein Complex alpha Subunits', 'Adaptor Proteins, Vesicular Transport', 'Animals', 'Biological Transport', 'Brain', 'Cattle', 'Clathrin', 'Coated Vesicles', 'Cytoplasmic Granules', 'Electrophoresis, Agar Gel', 'Electrophoresis, Polyacrylamide Gel', 'Epithelial Cells', 'Female', 'Immunohistochemistry', 'Intr... | 10,547,368 | [['D12.776.543.990.150.500.100'], ['D12.776.543.990.150'], ['B01.050'], ['G03.143'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['D12.776.543.990.200'], ['A11.284.430.214.190.875.190.880.180'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['E05.196.401.153', 'E05.301.300.100'], ['E05.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A plasma membrane pool of cholesteryl esters that may mediate the selective uptake of cholesteryl esters from high-density lipoproteins. | Selective uptake of high-density lipoprotein (HDL) cholesteryl esters without parallel uptake of HDL particles occurs by a nonendocytotic pathway that requires no specific apolipoprotein and results in the net delivery of cholesteryl esters to cells. Here we examine a reversibly cell-associated pool of cholesteryl este... | ['Adrenal Gland Neoplasms', 'Animals', 'Cell Membrane', 'Cells, Cultured', 'Cholesterol Esters', 'Cycloheximide', 'Kinetics', 'Lipoproteins, HDL', 'Mice', 'Oleic Acid', 'Oleic Acids', 'Rats'] | 2,713,387 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['B01.050'], ['A11.284.149'], ['A11.251'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['D03.383.621.808.240'], ['G01.374.661', 'G02.111.490'], ['D10.532.432', 'D12.776.521.479'], ['B01.050.150.900.649.313.992.635.505.500'], ... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Na+ channel accumulation on axolemma of afferent endings in nerve end neuromas in Apteronotus. | In mammals, cut sensory axons trapped in a nerve end neuroma have been shown to develop hyperexcitability, and to become a source of ectopic afferent discharge and abnormal sensation. We have explored cellular mechanisms underlying neuroma electrogenesis. First we confirmed that ectopic neuroma discharge develops in in... | ['Animals', 'Axons', 'Cell Membrane', 'Denervation', 'Electric Fish', 'Electrophysiology', 'Immunohistochemistry', 'Microscopy, Electron', 'Myelin Sheath', 'Nerve Regeneration', 'Neuroma', 'Neurons, Afferent', 'Sodium Channels'] | 2,554,205 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A11.284.149'], ['E04.525.210'], ['B01.050.150.900.493.378'], ['H01.158.344.528', 'H01.158.782.236'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro evaluation of the potential toxic effects of palladium nanoparticles on fibroblasts and lung epithelial cells. | Palladium nanoparticles have been increasingly used in catalytic processes, wastewater treatment, electronics, and biomedicine. However, recent evidence proved that these nanoparticles are able to induce adverse effects both in in vitro and in vivo models. Nevertheless, molecular mechanisms underlying the toxic effects... | ['A549 Cells', 'Animals', 'Apoptosis', 'Cell Cycle', 'Cell Cycle Proteins', 'Cell Line', 'Cell Proliferation', 'Cell Survival', 'DNA Damage', 'Epithelial Cells', 'Fibroblasts', 'Humans', 'Lung', 'Metal Nanoparticles', 'Palladium', 'Rats', 'Reactive Oxygen Species'] | 28,473,196 | [['A11.251.210.190.080', 'A11.251.860.180.080', 'A11.436.054'], ['B01.050'], ['G04.146.954.035'], ['G04.144'], ['D12.776.167'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G05.200'], ['A11.436'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['J01.637.512.600... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Serotonin reuptake inhibitor-induced sexual dysfunction and its treatment: a large-scale retrospective study of 596 psychiatric outpatients. | In the present study, a large-scale retrospective case review was undertaken to assess the incidence and type of sexual dysfunctions associated with serotonin reuptake inhibitor (SRI) therapy, in addition to the effects of three pharmacological antidotes (yohimbine, amantadine, cyproheptadine) on SRI-induced sexual dys... | ['Adult', 'Amantadine', 'Ambulatory Care', 'Aphrodisiacs', 'Cyproheptadine', 'Dopamine Agents', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Retrospective Studies', 'Serotonin Antagonists', 'Serotonin Uptake Inhibitors', 'Sexual Dysfunctions, Psychological', 'Yohimbine'] | 9,292,832 | [['M01.060.116'], ['D02.455.426.100.050.035'], ['E02.760.106', 'N02.421.585.106'], ['D27.505.696.282.045', 'D27.505.954.427.220.045'], ['D02.455.426.559.847.181.384.340', 'D03.383.621.160', 'D04.615.181.384.340'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer. | Increasing evidence suggests that the long non-coding RNA, HOX transcript antisense intergenic RNA (HOTAIR) is widely involved in the progression and metastasis of cancer. However, the specific role of HOTAIR in ovarian carcinogenesis remains to be fully elucidated. In the present study, the levels of HOTAIR were detec... | ['Adult', 'Apoptosis', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MicroRNAs', 'Middle Aged', 'Ovarian Neoplasms', 'RNA, Long Noncoding', 'rab GTP-Binding Proteins'] | 27,484,896 | [['M01.060.116'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['M01.060.116.630'], ['C04.588.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Removal of Chlorpyrifos by Water Hyacinth (Eichhornia crassipes) and the Role of a Plant-Associated Bacterium. | The objective of this research was to study the efficiency of water hyacinth (Eichhornia crassipes) and the role of any plant-associated bacteria in removing chlorpyrifos from water. The relative growth rate (RGR) of E. crassipes in the presence of 0.1 mg/L chlorpyrifos was not significantly different from that in its ... | ['Acinetobacter', 'Biodegradation, Environmental', 'Chlorpyrifos', 'Eichhornia', 'Plant Roots', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 25,976,881 | [['B03.440.400.425.537.050', 'B03.660.250.530.050'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['B01.650.940.800.575.912.250.827.500'], ['A18.400'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clonidine-evoked respiratory effects in anaesthetized rats. | The respiratory effects of stimulation of alpha2-adrenergic receptors were studied in spontaneously breathing anaesthetized rats that were neurally intact, or bilaterally vagotomized, or subjected to bilateral combined midcervical vagotomy and section of the carotid sinus nerves. An intravenous clonidine bolus (15 micr... | ['Adrenergic alpha-Agonists', 'Adrenergic alpha-Antagonists', 'Anesthesia', 'Animals', 'Benzazepines', 'Blood Pressure', 'Carotid Sinus', 'Clonidine', 'Dose-Response Relationship, Drug', 'Injections, Intravenous', 'Lung', 'Male', 'Rats', 'Rats, Wistar', 'Receptors, Adrenergic, alpha-2', 'Respiration', 'Respiratory Cent... | 16,282,369 | [['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['E03.155'], ['B01.050'], ['D03.633.100.079'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.114.186.456'], ['D03.383.129.308.436.500'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monokine mediated release of intracellular iron in tumor target cells in vitro. | Activated macrophages cocultured with tumor cells mediate intracellular iron release in both lytically-sensitive and lytically-resistant targets. The early inhibition of aconitase and loss of intracellular iron in tumor targets upon coincubation with activated macrophages have been proposed to be causally linked. In th... | ['Animals', 'Cell Line', 'Cytotoxicity, Immunologic', 'Endotoxins', 'In Vitro Techniques', 'Iron', 'Iron-Sulfur Proteins', 'Macrophage Activation', 'Macrophages', 'Mice', 'Mice, Inbred Strains', 'Monokines', 'Mycobacterium bovis', 'Neoplasms, Experimental', 'Proteins'] | 3,546,962 | [['B01.050'], ['A11.251.210'], ['G12.287'], ['D23.946.123.329'], ['E05.481'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D12.776.157.427.374.375', 'D12.776.556.579.374.375'], ['G12.287.500'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attitudes toward medical and genetic confidentiality in the Saudi research biobank: An exploratory survey. | Achieving a balance between giving access to information and respecting donors' confidentiality is a crucial issue for any biobank, with its large number of samples and associated information. Despite the existence of much empirical literature on confidentiality, there are too few surveys in the Middle East about the t... | ['Access to Information', 'Adolescent', 'Adult', 'Attitude', 'Biological Specimen Banks', 'Biomedical Research', 'Confidentiality', 'Female', 'Genetic Privacy', 'Humans', 'Informed Consent', 'Male', 'Medical Records', 'Middle Aged', 'Saudi Arabia', 'Surveys and Questionnaires', 'Young Adult'] | 26,806,715 | [['I01.880.604.473.352.500.030', 'L01.143.024', 'L01.737.030'], ['M01.060.057'], ['M01.060.116'], ['F01.100'], ['N02.278.065'], ['H01.770.644.145'], ['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['I01.880.604.473.352.500.320', 'I01.880.604.473.650.5... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Cardiovascular Disease Risk Among Young Urban Women. | BACKGROUND: Although young women are presumed to have low cardiovascular disease (CVD) risk and mortality, the mortality benefits secondary to ischemic heart disease have plateaued among young women, <50 years.MATERIALS AND METHODS: Women, 18-49 years (n = 595) among all participants (n = 1,045) in the Columbia Univers... | ['Adolescent', 'Adult', 'Anthropometry', 'Diabetes Mellitus', 'Ethnic Groups', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Status Disparities', 'Healthy Lifestyle', 'Humans', 'Hyperlipidemias', 'Hypertension', 'Logistic Models', 'Middle Aged', 'Overweight', 'Risk Factors', 'Self Report', 'Socioeconomic F... | 27,058,670 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['C18.452.394.750', 'C19.246'], ['M01.686.754', 'N01.224.317'], ['F01.100.150.500', 'N05.300.150.410'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['F01.829.458.205'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Subcellular localization, inhibiting specificity and catalytic properties of several aminooxidases from the human placenta]. | Human placenta was shown to contain practically all known types of aminooxidase, i.e., Membrane-bound and soluble monoamine oxidases A that predominantly oxidize serotonin (Km approximately 0.05 and 0.2 mM) and tyramine (Km approximately 0.03 and 0.085 mM), partly oxidize phenylethylamine (Km approximately 0.013 and 0.... | ['Benzylamine Oxidase', 'Cadaverine', 'Female', 'Histamine', 'Humans', 'Kinetics', 'Monoamine Oxidase', 'Monoamine Oxidase Inhibitors', 'Oxidation-Reduction', 'Phenethylamines', 'Placenta', 'Pregnancy', 'Serotonin', 'Subcellular Fractions', 'Substrate Specificity', 'Tyramine'] | 3,986,244 | [['D08.811.682.664.750.100'], ['D02.092.211.415.261', 'D02.092.782.258.174'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.664.750'], ['D27.505.519.389.616'], ['G02.700', 'G03.295.531'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrasonic purification of Bridge anticoagulant neutralizing agent (BANA) and a study on its effect on factor VIII inhibitor. | Ether precipitation of globulins from the supernatant fraction of prothrombin complex concentrate, followed by adsorption on tricalcium phosphate and elution gives a beta2 fraction termed Bridge anticoagulant neutralizing agent (BANA). Although this is completely free of all known blood clotting factors, it improves re... | ['Coagulants', 'Factor VIII', 'Humans', 'Methods', 'Ultrasonics'] | 432,913 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Poor Insight": A Capacity Perspective on Treatment Refusal in Serious Mental Illness. | For several decades, a protection standard has prevailed in determining the conditions under which a mental health provider, in concert with state authority, might intrude upon the civil rights of a person with serious mental illness. This approach contrasts with a treatment standard that guides consideration and asses... | ['Amputation', 'Cellulitis', 'Humans', 'Leg', 'Legal Guardians', 'Male', 'Middle Aged', 'Osteomyelitis', 'Schizophrenia', 'Treatment Refusal'] | 27,181,738 | [['E04.555.080'], ['C01.800.130', 'C01.830.200', 'C17.300.185', 'C23.550.470.756.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.380'], ['M01.060.116.630'], ['C01.160.495', 'C05.116.165.495'], ['F03.700.750'], ['F01.100.150.750.750', 'F01.145.488.887.750', 'I01.880.604.473.650.968', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The á1 | Cone snails use separately evolved venoms for prey capture and defence. While most use a harpoon for prey capture, the Gastridium clade that includes the well-studied Conus geographus and Conus tulipa, have developed a net hunting strategy to catch fish. This unique feeding behaviour requires secretion of "nirvana caba... | ['Adrenergic alpha-1 Receptor Antagonists', 'Animals', 'Conus Snail', 'Escape Reaction', 'Mollusk Venoms', 'Predatory Behavior', 'Receptors, Adrenergic, alpha-1', 'Zebrafish', 'Zebrafish Proteins'] | 31,780,714 | [['D27.505.519.625.050.200.100.100', 'D27.505.696.577.050.200.100.100'], ['B01.050'], ['B01.050.500.644.400.275'], ['F01.145.113.780.688', 'F01.145.367', 'F01.145.875.439.500.688', 'G07.568.500.590.688', 'G11.427.410.568.850.688'], ['D20.888.590', 'D23.946.580.590', 'D23.946.833.590'], ['F01.145.113.111.600', 'F01.145.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of community-based health insurance on the utilization of modern health care services: evidence from Burkina Faso. | OBJECTIVE: To quantify the impact of community-based health insurance (CBI) on utilization of health care services in rural Burkina Faso.METHODS: Propensity score matching was used to minimise the observed baseline differences in the characteristics of insured and uninsured groups such that the observed difference in h... | ['Adult', 'Aged', 'Burkina Faso', 'Community Networks', 'Female', 'Health Services', 'Humans', 'Insurance, Health', 'Male', 'Middle Aged', 'Young Adult'] | 19,036,467 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.058.290.190.245'], ['I01.880.853.500.300', 'L01.313.500.750.300.184', 'N02.421.143.202'], ['N02.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
The Troms? study: the prevalence of exercise-induced silent myocardial ischaemia and relation to risk factors for coronary heart disease in an apparently healthy population. | A random population sample of 294 men and 312 women aged 20-64 years, all apparently healthy, were examined following a screening to determine the prevalence of silent ischaemia and its relations to coronary risk factors. Based on exercise testing, the prevalence of silent ischaemia was 2.5% in men and 3.4% in women. I... | ['Adult', 'Aged', 'Blood Pressure', 'Coronary Disease', 'Electrocardiography', 'Exercise Test', 'Female', 'Health Status', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Norway', 'Prevalence', 'Regression Analysis', 'Risk Factors', 'Sex Factors'] | 1,623,859 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Single-feature inking and stamping: a versatile approach to molecular patterning. | A technique for micrometer-scale patterning of multiple functional biological molecules on surfaces is demonstrated. The technique is referred to as single-feature inking and stamping (SFINKS). It combines elements of dip-pen nanolithography and microcontact printing. "Inked" atomic force microscopy probes are used to ... | ['Biomimetic Materials', 'DNA, Single-Stranded', 'Microscopy, Fluorescence', 'Nanotechnology', 'Oligonucleotides', 'Pattern Recognition, Automated'] | 15,669,842 | [['J01.637.087'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['E01.370.350.515.458', 'E05.595.458'], ['H01.603', 'J01.897.520.600'], ['D13.695.578.424'], ['L01.399.750']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Influence of humidity and setting time on the push-out strength of mineral trioxide aggregate obturations. | The aim of this study is to assess how a wet environment curing affects the retention characteristics of mineral trioxide aggregate (MTA), and also to determine the time needed for curing. MTA obturations were carried out in perforated dentine slices and cured under different conditions (presence or absence of humidity... | ['Aluminum Compounds', 'Calcium Compounds', 'Dental Stress Analysis', 'Dentin', 'Drug Combinations', 'Humans', 'Humidity', 'Materials Testing', 'Oxides', 'Root Canal Filling Materials', 'Root Canal Obturation', 'Silicates', 'Time Factors'] | 16,934,637 | [['D01.056'], ['D01.146'], ['E06.308'], ['A14.549.167.900.280'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['E05.570'], ['D01.248.497.158.685', 'D01.650.550'], ['D25.339.859', 'J01.637.051.339.859'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Oral and genital human herpesvirus 8 and human papillomavirus in heterosexual partners. | BACKGROUND: The purpose of this study was to verify a possible co-infection of human herpesvirus 8 (HHV-8) in commonly associated human papillomavirus (HPV) penile lesions and to determine the frequency of detection of these viruses in the oral mucosa of their female counterparts.METHODS: Thirty-one male subjects under... | ['Adolescent', 'Adult', 'Alphapapillomavirus', 'Carcinoma, Squamous Cell', 'Chi-Square Distribution', 'Coinfection', 'Female', 'Genitalia, Female', 'Herpesviridae Infections', 'Herpesvirus 8, Human', 'Heterosexuality', 'Humans', 'Male', 'Middle Aged', 'Mouth Mucosa', 'Papillomavirus Infections', 'Penile Neoplasms', 'Sa... | 22,680,306 | [['M01.060.057'], ['M01.060.116'], ['B04.280.210.655.050', 'B04.613.204.655.050'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C01.218'], ['A05.360.319'], ['C01.925.256.466'], ['B04.280.210.400.700.330', 'B04.280.382.400... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages. | Autophagy plays a pro-survival role in the tamoxifen-resistant breast cancer cells. Herein we found that autophagy was concomitantly induced in tamoxifen-resistant MCF-7 (MCF-7TR5) cells through the dissociation of Bcl-2 from Beclin 1 and subsequent enhancement of interaction among the ATG14-Beclin1-PI3KC3 complex. Mor... | ['4-Butyrolactone', 'Autophagy', 'Breast Neoplasms', 'Cell Line, Tumor', 'DNA Damage', 'Female', 'Humans', 'MCF-7 Cells'] | 28,431,397 | [['D02.540.150', 'D03.383.312.150'], ['G04.011'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.630']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensory features as predictors of adaptive behaviors: A comparative longitudinal study of children with autism spectrum disorder and other developmental disabilities. | BACKGROUND: Children with autism spectrum disorder (ASD) and other developmental disabilities (DD) exhibit sensory features that differ from their typically developing peers. Prior cross-sectional research has demonstrated significant associations between elevated sensory features and lower adaptive behavior scores, ye... | ['Adaptation, Psychological', 'Autism Spectrum Disorder', 'Child', 'Child Behavior', 'Child, Preschool', 'Developmental Disabilities', 'Early Intervention, Educational', 'Female', 'Humans', 'Male', 'Mental Processes', 'Prognosis'] | 30,060,977 | [['F01.058'], ['F03.625.164.113'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['F03.625.421'], ['N02.421.143.130.320', 'N02.421.726.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463'], ['E01.789']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cardiac Damage Biomarkers and Heart Rate Variability Following a 118-Km Mountain Race: Relationship with Performance and Recovery. | This study aimed to assess the release of cardiac damage biomarkers jointly with cardiac autonomic modulation after a mountain ultramarathon. Such knowledge and the possible relationship of these markers with race time is of primary interest to establish possible recommendations upon athletes' recovery and return to tr... | ['Adult', 'Biomarkers', 'Heart Rate', 'Humans', 'Male', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Physical Endurance', 'Running', 'Troponin T', 'Vagus Nerve'] | 31,827,345 | [['M01.060.116'], ['D23.101'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.584.625', 'D12.644.548.585.625', 'D12.776.631.590'], ['D12.644.541'], ['G11.427.680', 'I03.450.642.845.054.600'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The effects of precompetition massage on the kinematic parameters of 20-m sprint performance. | The purpose of this study was to investigate what effect precompetition massage has on short-term sprint performance. Twenty male collegiate games players, with a minimum training/playing background of 3 sessions per week, were assigned to a randomized, counter-balanced, repeated-measures designed experiment used to an... | ['Adult', 'Athletic Performance', 'Biomechanical Phenomena', 'Humans', 'Male', 'Massage', 'Running'] | 20,386,129 | [['M01.060.116'], ['I03.450.642.845.054'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.599.750.750', 'E02.779.867.880.750', 'E02.831.535.867.880.750'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Validity of the Keith Edwards scoring system for the diagnosis of childhood pulmonary tuberculosis]. | INTRODUCTION: The diagnosis of childhood pulmonary tuberculosis remains a challenge. The effectiveness of the Keith Edwards scoring system used to diagnose tuberculosis is controversial. We evaluated this scoring system in the present study.METHODS: A prospective randomized study was conducted between March 2008 and De... | ['Child', 'Child, Preschool', 'Decision Support Techniques', 'Democratic Republic of the Congo', 'Developing Countries', 'Diagnostic Techniques, Respiratory System', 'Female', 'Humans', 'Infant', 'Male', 'Mass Screening', 'Predictive Value of Tests', 'Probability', 'Prospective Studies', 'Tuberculosis, Pulmonary'] | 24,309,200 | [['M01.060.406'], ['M01.060.406.448'], ['E05.245', 'L01.313.500.750.190'], ['Z01.058.290.100.220'], ['I01.615.500.300'], ['E01.370.386'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.98... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Knowledge and perception of young adults in Nigeria on effectiveness of condom use in prevention of sexually transmitted infections. | BACKGROUND: Although sexually transmitted infections (STIs) are a global health problem affecting every region of the world, the higher prevalence and mortality rate of STIs in developing countries of the world, like Nigeria, make them serious public health issues in this region.OBJECTIVE: The aim of this study is to a... | ['Adolescent', 'Adult', 'Condoms', 'Contraception Behavior', 'Female', 'Health Knowledge, Attitudes, Practice', 'Heterosexuality', 'Homosexuality', 'Humans', 'Male', 'Nigeria', 'Safe Sex', 'Sexual Behavior', 'Sexually Transmitted Diseases', 'Surveys and Questionnaires', 'Young Adult'] | 26,536,574 | [['M01.060.057'], ['M01.060.116'], ['E07.190.270.150'], ['F01.145.688.500', 'G08.686.784.891.500'], ['F01.100.150.500', 'N05.300.150.410'], ['F01.145.802.975.400', 'G08.686.867.400'], ['F01.145.802.975.500', 'G08.686.867.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.190.565'], ['F01.145.802.845'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Gender-Affirming Pharmacological Interventions for Youth With Gender Dysphoria: When Treatment Guidelines Are Not Enough. | Youth with gender dysphoria, also known as transgender youth, are increasingly presenting to multidisciplinary clinics within academic pediatric centers across the United States. Gender-affirming pharmacological interventions for adolescents with gender dysphoria may be used to promote positive psychological well-being... | ['Adolescent', 'Female', 'Gender Dysphoria', 'Gender Identity', 'Humans', 'Male', 'Transgender Persons'] | 28,660,776 | [['M01.060.057'], ['F03.835.550'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.777.500']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Emerging Trends in Clinical Research: With Implications for Population Health and Health Policy. | Policy Points: Significant advances in clinical medicine that have broader societal relevance may be less accessible to population health researchers and policymakers because of increased specialization within fields. We describe important recent clinical advances and discuss their broader societal impact. These advanc... | ['Clinical Nursing Research', 'Clinical Trials as Topic', 'Forecasting', 'Health Equity', 'Health Policy', 'Humans', 'Population Health'] | 29,870,114 | [['H01.770.644.145.390.234', 'H02.478.395.234', 'N04.590.233.508.613.234'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['I01.320'], ['N04.590.374.350.500', 'N05.300.430.383'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
[Ultrasound-guided biopsy of the pancreas: a multicenter study]. | OBJECTIVE: Members of "Asociaci?n de Ecograf?a Digestiva" decided to carry out a multicenter retrospective study on fine-needle aspiration biopsy for pancreatic space-occupying lesions under ultrasonographic guidance and via the percutaneous route in order to assess this technique s performance versus endoscopic ultras... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biopsy, Fine-Needle', 'Endoscopy, Gastrointestinal', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreas', 'Pancreatic Diseases', 'Retrospective Studies', 'Ultrasonography'] | 18,052,647 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.370.372.250.250', 'E01.370.388.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies. | BACKGROUND: Lonafarnib (LNF) is a protein farnesyl transferase (FTase) inhibitor that has shown synergistic activity with taxanes in preclinical models and early stage clinical trials. Preclinical findings suggested tubulin acetylation and FTase expression levels may be important determinants of drug sensitivity that w... | ['Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Docetaxel', 'Enzyme Inhibitors', 'Farnesyltranstransferase', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Pilot Projects', 'Piperidines', 'Pyridines', 'Taxoids'] | 21,365,629 | [['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['D27.505.519.389'], ['D08.811.913.225.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.72... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Donor IFN-gamma receptors are critical for acute CD4(+) T cell-mediated cardiac allograft rejection. | Recent studies using mouse models demonstrate that CD4(+) T cells are sufficient to mediate acute cardiac allograft rejection in the absence of CD8(+) T cells and B cells. However, the mechanistic basis of CD4-mediated rejection is unclear. One potential mechanism of CD4-mediated rejection is via elaboration of proinfl... | ['Animals', 'CD4 Antigens', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Female', 'Graft Rejection', 'Heart Transplantation', 'Interferon-gamma', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Receptors, Interferon', 'Transplantation, Homologous'] | 11,673,565 | [['B01.050'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microdeletions of 3p21.31 characterized by developmental delay, distinctive features, elevated serum creatine kinase levels, and white matter involvement. | Interstitial deletions of chromosome 3 are rare, and only one patient with a microdeletion of 3p21.31 has been reported to date. We identified two additional cases of patients with microdeletions of 3p21.31. The characteristic clinical features of developmental delay and distinctive facial features (including arched ey... | ['Abnormalities, Multiple', 'Adolescent', 'Child, Preschool', 'Chromosome Deletion', 'Chromosomes, Human, Pair 3', 'Creatine Kinase', 'Developmental Disabilities', 'Female', 'Humans', 'Leukoencephalopathies', 'Nerve Tissue Proteins', 'Phenotype'] | 24,039,031 | [['C16.131.077'], ['M01.060.057'], ['M01.060.406.448'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187.520.300.235.250', 'G05.360.162.520.300.235.250'], ['D08.811.913.696.640.150'], ['F03.625.421'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica. | BACKGROUND: A polyspecific, intrathecal humoral immune response against neurotropic viruses such as measles, rubella and varicella zoster virus (MRZ reaction, MRZR) is present in 80-100% of patients with multiple sclerosis (MS), but has not to date been evaluated in patients with neuromyelitis optica (NMO).AIMS: To eva... | ['Adult', 'Aged', 'Antibodies, Viral', 'Chickenpox', 'Diagnosis, Differential', 'Female', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Measles', 'Middle Aged', 'Multiple Sclerosis', 'Neuromyelitis Optica', 'Optic Nerve', 'Rubella'] | 18,270,237 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C01.925.256.466.930.250'], ['E01.171'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.58... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Probing the self-assembly and the accompanying structural changes of hydrophobin SC3 on a hydrophobic surface by mass spectrometry. | The fungal class I hydrophobin SC3 self-assembles into an amphipathic membrane at hydrophilic-hydrophobic interfaces such as the water-air and water-Teflon interface. During self-assembly, the water-soluble state of SC3 proceeds via the intermediate alpha-helical state to the stable end form called the beta-sheet state... | ['Air', 'Amino Acid Sequence', 'Circular Dichroism', 'Detergents', 'Endopeptidases', 'Formates', 'Fungal Proteins', 'Kinetics', 'Mass Spectrometry', 'Metalloendopeptidases', 'Molecular Sequence Data', 'Oxygen', 'Pepsin A', 'Peptides', 'Polytetrafluoroethylene', 'Protein Binding', 'Protein Conformation', 'Protein Struct... | 15,345,568 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.867.151'], ['D27.720.877.265', 'J01.516.381'], ['D08.811.277.656.300'], ['D02.241.081.420'], ['D12.776.354'], ['G01.374.661', 'G02.111.490'], ['E05.196.566'], ['D08.811.277.656.300.480', 'D08.811.277.656.675.374'], ['... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Dual mode of action of glucose pentaacetates on hormonal secretion from the isolated perfused rat pancreas. | Isolated perfused rat pancreases were exposed, in the presence of 10. 0 mM L-leucine, to either alpha-D-glucose pentaacetate, beta-L-glucose pentaacetate, or unesterified D-glucose, all tested at a 1.7 mM concentration. The pentaacetate ester of alpha-D-glucose and, to a lesser extent, that of beta-L-glucose stimulated... | ['Animals', 'Female', 'Glucagon', 'Glucose', 'In Vitro Techniques', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Leucine', 'Oscillometry', 'Perfusion', 'Rats', 'Rats, Wistar', 'Somatostatin', 'Stereoisomerism', 'Time Factors'] | 9,755,079 | [['B01.050'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D09.947.875.359.448'], ['E05.481'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', 'A06.300.414'], ['D12.125.070.637', 'D12.125.142.441'], ['E05.654'], ['E05.680'], ['B01.050.150.900.649.313.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ensuring the viability of gastric transplants used in esophagoplasty using hemomotordynamic monitoring]. | A new method of hemomotordynamic monitoring of an isoperistaltic gastric graft in esophagoplasty was evaluated in the clinic in 27 patients. The method was found to be adequate in determining and ensuring viability of the grafts. The presence of an intramural pulse in all parts of the graft is the criterion of its viab... | ['Esophagoplasty', 'Female', 'Graft Survival', 'Humans', 'Intraoperative Period', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Stomach'] | 2,722,037 | [['E04.210.355'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['M01.060.116.630'], ['E01.370.520'], ['A03.556.875.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Competitive incorporation of perrhenate and nitrate into sodalite. | Nuclear waste storage tanks at the Hanford site in southeastern Washington have released highly alkaline solutions, containing radioactive and other contaminants, into subsurface sediments. When this waste reacts with subsurface sediments, feldspathoid minerals (sodalite, cancrinite) can form, sequestering pertechnetat... | ['Anions', 'Microscopy, Electron, Scanning', 'Minerals', 'Nitrates', 'Radioactive Waste', 'Rhenium', 'Solutions', 'Temperature', 'Washington', 'Water', 'X-Ray Absorption Spectroscopy', 'X-Ray Diffraction'] | 25,280,127 | [['D01.248.497.158'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.578'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D20.693.638', 'D20.944.380.638', 'D27.888.426.500.638', 'N06.850.460.710.380.638', 'N06.850.810.485'], ['D01.268.556.787', 'D01.268.956.750', 'D01.552.544.787'], ['D26.776'], ['G01... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Nusinersen in type 1 SMA infants, children and young adults: Preliminary results on motor function. | We report preliminary data on the six month use of Nusinersen in 104 type 1 patients of age ranging from three months to 19 years, 9 months. Ten of the 104 were classified as 1.1, 58 as 1.5 and 36 as 1.9. Three patients had one SMN2 copy, 65 had two and 24 had three copies. In 12 the SMN2 copy number was not available.... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Motor Skills', 'Neurologic Examination', 'Oligonucleotides', 'Spinal Muscular Atrophies of Childhood', 'Treatment Outcome', 'Young Adult'] | 29,960,818 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F02.808.260'], ['E01.370.376.550', 'E01.370.600.550'], ['D13.695.578.424'], ['C10.228.854.468.800', 'C10.574.500.812', 'C10.574.562.500.750', 'C10.668.467.500.750', 'C16.320.400.765'], ['E01.789.8... | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
BHRF1 exerts an antiapoptotic effect and cell cycle arrest via Bcl-2 in murine hybridomas. | Apoptosis has been widely studied in order to find methods to increase the life-span and production performance in large-scale animal cell cultures. The use of anti-apoptotic genes has emerged as an efficient method to reduce apoptosis in a variety of biotechnological relevant cell lines, including CHO and hybridomas, ... | ['Animals', 'Apoptosis', 'Batch Cell Culture Techniques', 'Benzopyrans', 'Cell Cycle Checkpoints', 'Cell Line', 'Hybridomas', 'Membrane Potential, Mitochondrial', 'Mice', 'Mitochondria', 'Nitriles', 'Proto-Oncogene Proteins c-bcl-2', 'Thiazoles', 'Transfection', 'Up-Regulation', 'Viral Proteins'] | 26,057,602 | [['B01.050'], ['G04.146.954.035'], ['E05.481.500.249.124'], ['D03.383.663.283', 'D03.633.100.150'], ['G04.144.109'], ['A11.251.210'], ['A11.251.353.485', 'A11.251.600.485'], ['G03.295.770.500', 'G04.580.550', 'G07.265.675.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.430.214.190.875.564', 'A11.284.835.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonclinical pharmacologic and toxicologic considerations for evaluating biologic products. | Prior to a Phase 1 clinical study, products are studied preclinically to establish evidence of pharmacologic activity, gain an understanding of the mechanism of action, evaluate the potential human risk, and establish a clinical study dose range. Although it is possible to follow this generic itinerary for the developm... | ['Biological Products', 'Drug Evaluation, Preclinical', 'Drugs, Investigational', 'Humans', 'Research Design', 'Risk Factors', 'United States', 'United States Food and Drug Administration'] | 2,602,582 | [['D20.215'], ['E05.290.750', 'E05.337.550'], ['D26.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500', 'H01.770.644.728'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['Z01.107.567.875'], ['I01.409.418.750.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Diagnostic utility of immunochemical fecal occult blood tests to detect lower gastrointestinal lesions in patients with chronic kidney disease. | PURPOSE: The immunochemical fecal occult blood test (iFOBT) is a useful method to screen for lower gastrointestinal (GI) bleeding-related lesions. However, few studies have investigated the diagnostic utility of iFOBT in chronic kidney disease (CKD).METHODS: We included 691 patients with nondialysis-dependent CKD stage... | ['Aged', 'Colonoscopy', 'Demography', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Immunohistochemistry', 'Lower Gastrointestinal Tract', 'Male', 'Middle Aged', 'Occult Blood', 'Prevalence', 'ROC Curve', 'Renal Insufficiency, Chronic'] | 25,868,513 | [['M01.060.116.100'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Stability of fecapentaene-12 and its carcinogenicity in F-344 rats. | Carcinogenicity studies of the fecal mutagen fecapentaene-12 (FP-12) have been hampered because of its apparent instability. We report here that: (i) contrary to the popular belief, FP-12 is quite stable, particularly at micromolar to nanomolar concentration; and (ii) its characteristic spectrophotometric absorbance sp... | ['Animals', 'Cattle', 'Cells, Cultured', 'Colon', 'DNA', 'DNA Damage', 'Drug Stability', 'Epithelial Cells', 'Epithelium', 'Humans', 'Mutagens', 'Neoplasms, Experimental', 'Polyenes', 'Rats', 'Rats, Inbred F344', 'Spectrometry, Fluorescence'] | 2,013,124 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['D13.444.308'], ['G05.200'], ['E05.916.330'], ['A11.436'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.888.569.468'], ['C04.619', 'E05.598.500.496'], ['D02.455.326.271.665'], ['B0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intra-operative radiation therapy for malignant brain tumors: rationale, method, and treatment results of cerebral glioblastomas. | In radiation therapy for malignant brain tumours, the dose of radiation that can be safely delivered to a tumour is limited by the radiation tolerance of the adjacent normal brain tissue. Among various radiation modalities to produce local tumour eradication without unacceptable complications, we chose a large, single ... | ['Adolescent', 'Adult', 'Aged', 'Animals', 'Brain', 'Brain Neoplasms', 'Combined Modality Therapy', 'Cranial Irradiation', 'Female', 'Follow-Up Studies', 'Glioblastoma', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Transplantation', 'Pilot Projects', 'Radiotherapy Dosage', 'Radiotherapy, Adjuvant', 'Radiotherapy, High-En... | 7,709,789 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E02.186'], ['E02.815.190'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.6... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metallothionein deficiency enhances skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate in metallothionein-null mice. | To clarify the physiological role(s) of metallothionein (MT) in carcinogenesis, we studied the susceptibility of MT-null mice to chemically mediated carcinogenesis in the 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced two-stage carcinogenesis model. The MT-null mice were subjec... | ['9,10-Dimethyl-1,2-benzanthracene', 'Animals', 'Cell Division', 'Female', 'Genes, ras', 'Metallothionein', 'Mice', 'Mice, Inbred C57BL', 'Mutation', 'Polymerase Chain Reaction', 'Skin', 'Skin Neoplasms', 'Tetradecanoylphorbol Acetate'] | 12,807,749 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G05.360.340.024.340.375.500.791.550'], ['D12.776.556.670'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice. | OBJECTIVE: Imatinib has been reported to induce regression of type 2 diabetes in chronic leukemia patients. However, the mechanism of diabetes amelioration by imatinib is unknown, and it is uncertain whether imatinib has effects on type 2 diabetes itself without other confounding diseases like leukemia. We studied the ... | ['Adipose Tissue', 'Animals', 'Benzamides', 'Cell Cycle Proteins', 'Cell Line, Tumor', 'Diabetes Mellitus, Type 2', 'Endoplasmic Reticulum', 'Eukaryotic Initiation Factor-2', 'Humans', 'Imatinib Mesylate', 'Immunohistochemistry', 'In Situ Nick-End Labeling', 'Insulin Resistance', 'Insulin-Secreting Cells', 'JNK Mitogen... | 19,171,749 | [['A10.165.114'], ['B01.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['D12.776.167'], ['A11.251.210.190', 'A11.251.860.180'], ['C18.452.394.750.149', 'C19.246.300'], ['A11.284.430.214.190.875.248'], ['D12.776.835.725.868.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells. | T cell activation is known to be critically regulated by the extent and duration of TCR-induced signaling pathways. The NFAT family of transcription factors is believed to play an important role in coupling these quantitative differences in TCR-induced signaling events into changes in gene expression. In this study we ... | ['Animals', 'Apoptosis', 'CD4-Positive T-Lymphocytes', 'CD40 Ligand', 'Cells, Cultured', 'DNA-Binding Proteins', 'Down-Regulation', 'Drug Synergism', 'Fas Ligand Protein', 'Female', 'Interferon-gamma', 'Interleukin-2', 'Interleukin-4', 'L-Selectin', 'Leukemia Virus, Murine', 'Leukocyte Common Antigens', 'Ligands', 'Lym... | 11,994,444 | [['B01.050'], ['G04.146.954.035'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.543.550.198', 'D23.529.374.750.124'], ['A11.251'], ['D12.776.260'], ['G02.111.240', 'G05.308.200', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Digestive enzyme activities in the guts of bonnethead sharks (Sphyrna tiburo) provide insight into their digestive strategy and evidence for microbial digestion in their hindguts. | Few investigations have studied digestive enzyme activities in the alimentary tracts of sharks to gain insight into how these organisms digest their meals. In this study, we examined the activity levels of proteases, carbohydrases, and lipase in the pancreas, and along the anterior intestine, spiral intestine, and colo... | ['Acetylglucosaminidase', 'Aminopeptidases', 'Animals', 'Carbohydrate Metabolism', 'Colon', 'Digestion', 'Digestive System', 'Intestinal Mucosa', 'Intestines', 'Lipase', 'Microbiota', 'Pancreas', 'Peptide Hydrolases', 'Sharks', 'Time Factors', 'beta-Glucosidase'] | 26,239,220 | [['D08.811.277.450.483.180.500'], ['D08.811.277.656.350.100'], ['B01.050'], ['G02.111.158', 'G03.191'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['G07.203.650.250', 'G10.261.190'], ['A03'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['D08.811.277.352.100.400'], ['G06.591', 'G16.500.275.157.049.100.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The hydrogen ion equilibria of horseradish peroxidase and apoperoxidase. | 1. The reversible proton dissociation equilibria of peroxidase, apoperoxidase and haem-recombined apoperoxidase have been explored in 150mm-potassium chloride at 20 degrees C at pH3-11.5. 2. Complementary heat measurements have been made of the classes of titratable groups to determine their intrinsic DeltaH dissociati... | ['Amino Acids', 'Binding Sites', 'Carbohydrates', 'Chemical Phenomena', 'Chemistry, Physical', 'Heme', 'Histidine', 'Hydrogen-Ion Concentration', 'Imidazoles', 'Molecular Weight', 'Peroxidases', 'Potentiometry', 'Protons', 'Spectrum Analysis', 'Tyrosine'] | 5,135,245 | [['D12.125'], ['G02.111.570.120'], ['D09'], ['G02'], ['H01.181.529'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D12.125.072.329', 'D12.125.142.308'], ['G02.300'], ['D03.383.129.308'], ['G02.494'], ['D08.811.682.732'], ['E05.196.922.750', 'E05... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlating gene promoters and expression in gene disruption experiments. | MOTIVATION: Finding putative transcription factor binding sites in the upstream sequences of similarly expressed genes has recently become a subject of intensive studies. In this paper we investigate how much gene expression regulation can be attributed to the presence of various binding sites in the gene promoters by ... | ['Algorithms', 'Binding Sites', 'DNA, Fungal', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Gene Silencing', 'Promoter Regions, Genetic', 'Protein Binding', 'Research', 'Saccharomyces cerevisiae', 'Statistics as Topic', 'Transcription Factors'] | 12,386,000 | [['G17.035', 'L01.224.050'], ['G02.111.570.120'], ['D13.444.308.300'], ['E05.393.332'], ['G05.308'], ['G05.308.203.374'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.679', 'G03.808'], ['H01.770.644'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['E05.318.740'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[The surgeon as a prognostic factor in the treatment of cancer of the rectum]. | The study of prognostic factors in neoplastic rectal surgery is enriched with a new element, namely, the role of the surgeon. The aim of this study was to evaluate whether this was true of our own experience. We selected 118 patients with rectal cancer operated on with a radical intent by two different surgeons and ana... | ['Age Factors', 'Analysis of Variance', 'Colorectal Surgery', 'Female', 'Humans', 'Male', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', "Physician's Role", 'Prognosis', 'Rectal Neoplasms', 'Retrospective Studies', 'Sex Factors', 'Survival Analysis'] | 12,038,109 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['H02.403.810.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C23.550.727.650'], ['C04.697.655', 'C23.550.727.655'], ['E01.789.625'], ['F01.829.316.616.625.600'], ['E01.789'], ['C04.588.2... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical analysis of borderline ovarian tumors. | PURPOSE: The goal of this study was to evaluate the incidence and clinical features of borderline ovarian tumors (BOTS).METHODS: We retrospectively performed chart reviews of 22 patients with BOTS who were diagnosed and treated in the university medical center from 1998 to 2009 inclusively.RESULTS: BOTS among ovarian p... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Ovarian Neoplasms', 'Retrospective Studies', 'Young Adult'] | 21,446,329 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E01.789.625'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['E05.318.372.500.500.500', ... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Contrast-dose relation in first-pass myocardial MR perfusion imaging. | PURPOSE: To determine the regime of linear contrast enhancement in human first-pass perfusion cardiovascular magnetic resonance (CMR) imaging to improve accuracy in myocardial perfusion quantification.MATERIALS AND METHODS: A total of 10 healthy subjects were studied on a clinical 1.5T MR scanner. Seven doses of Gd-DTP... | ['Adult', 'Contrast Media', 'Dose-Response Relationship, Drug', 'Female', 'Gadolinium DTPA', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Linear Models', 'Magnetic Resonance Angiography', 'Male', 'Myocardium'] | 17,520,736 | [['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['L01.224.308'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Contribution of the serine protease HtrA in Escherichia coli to infection in foxes. | Escherichia coli can cause severe, acute hemorrhagic pneumonia and systemic infection in farmed foxes, raccoon dogs and minks, leading to considerable economic losses to the farmers. It is well established that the htrA-encoded serine protease HtrA is critical for bacterial growth and survival under stress, and HtrA ha... | ['Animal Diseases', 'Animals', 'Bacterial Proteins', 'Biofilms', 'Cold Shock Proteins and Peptides', 'Escherichia coli', 'Escherichia coli Infections', 'Foxes', 'Gene Expression Regulation, Bacterial', 'Gene Knockout Techniques', 'Heat-Shock Proteins', 'Mice', 'Periplasmic Proteins', 'Pneumonia', 'Sequence Deletion', '... | 31,158,492 | [['C22'], ['B01.050'], ['D12.776.097'], ['A20.593', 'G06.120'], ['D12.644.360.175', 'D12.776.476.175'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['B01.050.150.900.649.313.750.250.216.250'], ['G05.308.300'], ['E05.393.335.750'], ['D12.776.580.216'], ['B01.050.150.900.649.313.9... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monitoring the past and choosing the future: the prefrontal cortical influences on voluntary action. | Choosing between equivalent response options requires the resolution of ambiguity. One could facilitate such decisions by monitoring previous actions and implementing transient or arbitrary rules to differentiate response options. This would reduce the entropy of chosen actions. We examined voluntary action decisions d... | ['Adolescent', 'Adult', 'Choice Behavior', 'Decision Making', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Magnetoencephalography', 'Male', 'Prefrontal Cortex', 'Reaction Time', 'Young Adult'] | 29,739,978 | [['M01.060.057'], ['M01.060.116'], ['F02.463.785.373.346'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E01.370.376.500', 'E01.370.405.440', 'E05.540.500'], ['A08.186.211.200.885.287.500.270.700'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['M01.0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultrastructural GABA immunocytochemistry in the mossy fiber terminals of Wistar and genetic absence epileptic rats receiving amygdaloid kindling stimulations. | The existence of absence epilepsy and temporal lobe epilepsy in the same patient is not common in clinical practice. The reason why both types of seizures are rarely seen in the same patient is not well understood. Therefore, we aimed to investigate kindling in a well known model of human absence epilepsy, genetic abse... | ['Amygdala', 'Animals', 'Dentate Gyrus', 'Disease Models, Animal', 'Epilepsy, Absence', 'Epilepsy, Temporal Lobe', 'Genetic Predisposition to Disease', 'Hippocampus', 'Kindling, Neurologic', 'Male', 'Microscopy, Immunoelectron', 'Mossy Fibers, Hippocampal', 'Neural Inhibition', 'Rats', 'Rats, Mutant Strains', 'Rats, Wi... | 21,195,064 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.287.500.345.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.490.375.260', 'C10.228.140.490.493.125'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['C23.550.291.687.5... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Guideline for the production of multicentre physiological reference values using the same measurement system. A proposal of the Catalan Association for Clinical Laboratory Sciences. | This article is intended as a guide for the production of biological reference values of healthy people (physiological reference values) by several clinical laboratories using the same measurement system. This guide is a proposal from the Catalan Association of Clinical Laboratory Sciences to be applied worldwide at a ... | ['Clinical Chemistry Tests', 'Clinical Laboratory Techniques', 'Humans', 'Multicenter Studies as Topic', 'Reference Standards', 'Reference Values', 'Research Design'] | 15,327,013 | [['E01.370.225.124', 'E05.200.124'], ['E01.370.225', 'E05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.658', 'N05.715.360.330.643', 'N06.850.520.450.643'], ['E05.978.808'], ['E05.978.810'], ['E05.581.500', 'H01.770.644.728']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Superiority of tissue-culture-grown antigens over egg-grown antigens for serologic diagnosis of influenza B virus infections. | Acute and convalescent sera obtained from 10 adults and 21 children who were infected with influenza B virus were tested by hemagglutination inhibition. Of four antigens used, two tissue-culture-grown antigens were superior to either egg-grown or egg-grown, ether-treated antigens in detecting fourfold antibody rise dur... | ['Antigens, Viral', 'Cells, Cultured', 'Eggs', 'Hemagglutination Inhibition Tests', 'Humans', 'Influenza B virus', 'Influenza, Human'] | 3,723,116 | [['D23.050.327'], ['A11.251'], ['G07.203.300.470', 'J02.500.470'], ['E01.370.225.812.735.370', 'E05.200.812.735.370', 'E05.478.594.760.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.407.410'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Toxicity and narcotic effect of sodium oxybutyrate and ketalar at different periods of combined radiation lesion, burn injury and irradiation exposure]. | It has been shown that there are differences in the action of sodium hydroxybutyrate and ketamine depending on the stage and type of exposure. Alterations in the duration of anesthesia within the first four days after ionizing radiation are directly opposite to those seen under the conditions of the combined radiation-... | ['Analgesics, Opioid', 'Animals', 'Atmosphere Exposure Chambers', 'Burns', 'Gamma Rays', 'Hydroxybutyrates', 'Hypoxia', 'Ketamine', 'Lethal Dose 50', 'Mice', 'Radiation Injuries, Experimental', 'Sodium Oxybate', 'Time Factors'] | 2,867,931 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050'], ['E07.079'], ['C26.200'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['D02.241.081.114.937', 'D02.241.511.429', 'D10.251.400.143.781'], ['C23.888.852.079'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Substance use by college students: the role of intrinsic versus extrinsic motivation for athletic involvement. | Certain types of athletic involvement may confer risk for substance use by college students. This study investigated whether motivational factors play a role in the relationship between athletic involvement and substance use. Intercollegiate athletes (n=98) and exercisers (n=120) were surveyed about substance use and m... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Male', 'Motivation', 'Sports', 'Students', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Universities'] | 16,938,065 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['I03.450.642.845'], ['M01.848'], ['C25.775', 'F03.900'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['I02.783.830', 'J03.832.830']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Early myocardial lesions induced by cardiotoxic compounds in Sprague-Dawley rats. | Early focal myocardial lesions in rats induced by five cardiotoxic compounds were histopathologically observed 1 hr and 4 hr after a single intravenous injection with 1/10 LD50 and LD50. The lesions were observed 1 hr and 4 hr after the treatment with LD50 of isoproterenol (ISP), 4 hr with 1/10 LD50 of ISP, 4 hr with L... | ['Animals', 'Caffeine', 'Cyclophosphamide', 'Doxorubicin', 'Heart', 'Hydralazine', 'Isoproterenol', 'Lethal Dose 50', 'Male', 'Myocardial Contraction', 'Myocardium', 'Rats', 'Rats, Sprague-Dawley'] | 8,844,612 | [['B01.050'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['A07.541'], ['D03.383.710.605.500'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Presence and expression of terminal oxygen reductases in strictly anaerobic sulfate-reducing bacteria isolated from salt-marsh sediments. | In the anaerobic sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough genes were found encoding membrane terminal oxygen reductases of two types: a cytochrome c oxidase and a cytochrome bd oxidase, both enzymes are terminal oxidases typical of facultative or aerobic microorganisms (Heidelberg JF, et al., The... | ['Anaerobiosis', 'Cytochrome d Group', 'Cytochromes b', 'Desulfovibrio vulgaris', 'Electron Transport Complex IV', 'Geologic Sediments', 'Molecular Sequence Data', 'Oxidoreductases', 'Oxygen', 'Oxygen Consumption', 'Phylogeny', 'Portugal', 'Seawater', 'Sequence Analysis, DNA', 'Sulfur-Reducing Bacteria'] | 18,457,966 | [['G02.111.062', 'G03.078'], ['D08.244.300', 'D12.776.422.220.300'], ['D08.244.187.249', 'D12.776.422.220.187.249'], ['B03.440.425.410.350.875', 'B03.660.125.144.500.875.875', 'B03.900.350.875'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Intramural neurofibroma of the trachea treated by multiple stents. | The case history is presented of a patient in whom an intramural tracheal neurofibroma developed, causing severe airway stenosis. The patient was treated with multiple stents over a period of 5 years because of progression of the disease and associated airflow limitation. Clinicians should be aware of this rare complic... | ['Bronchoscopy', 'Female', 'Humans', 'Middle Aged', 'Neurofibroma', 'Neurofibromatosis 1', 'Respiratory Function Tests', 'Stents', 'Tracheal Neoplasms'] | 11,413,361 | [['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.580.600.580', 'C10.551.775.500.750', 'C10.668.829.725.500.600'], ['C04.557.580.600.580.590.650', 'C04.700.631.650', 'C10.562.600.500', 'C10.574.500.549.400',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modelling eye-head coordination without pre-planning--a reflex-based approach. | The gaze orientation system is a prime example of the CNS using multiple platforms to achieve its goal. To move the gaze in space, the eyes, head, and body cooperate to place the image of the target on the fovea. Understanding the underlying neural circuitry innervating this collaboration could also be a cue to underst... | ['Computer Simulation', 'Eye Movements', 'Feedback, Sensory', 'Fixation, Ocular', 'Head Movements', 'Humans', 'Models, Neurological', 'Muscle Contraction', 'Oculomotor Muscles', 'Postural Balance', 'Reflex'] | 23,366,948 | [['L01.224.160'], ['G11.427.410.140', 'G14.350'], ['F04.754.137.301.500', 'F04.754.308.500.500', 'F04.754.339', 'G07.410.732.500'], ['G14.350.253'], ['G11.427.410.478'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['G11.427.494'], ['A02.633.567.700'], ['F02.830.816.541.752', 'G07.888.750.500',... | ['Information Science [L]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Results from two online surveys comparing sexual risk behaviors in Hispanic, black, and white men who have sex with men. | Many men who have sex with men (MSM) are among those who increasingly use the internet to find sexual partners. Few studies have compared behavior by race/ethnicity in internet-based samples of MSM. We examined the association of race/ethnicity with HIV risk-related behavior among 10,979 Hispanic, black, and white MSM ... | ['Adolescent', 'Adult', 'African Americans', 'European Continental Ancestry Group', 'Female', 'HIV Infections', 'HIV Seropositivity', 'Health Surveys', 'Hispanic Americans', 'Humans', 'Internet', 'Male', 'Risk-Taking', 'Sexual Behavior', 'Sexual Partners', 'Unsafe Sex', 'Young Adult'] | 21,691,760 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.400'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Acute versus chronic pain experience in Alzheimer's disease. a new questionnaire. | The low use of analgesics in patients with Alzheimer's disease (AD), compared to nondemented elderly persons, is generally explained by (1) a lower prevalence of painful conditions in the former group and (2) undertreatment of pain due to a decrease in communicative abilities in AD. However, considering the neuropathol... | ['Acute Disease', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Mental Status Schedule', 'Middle Aged', 'Pain', 'Pain Measurement', 'Pain Threshold'] | 10,629,356 | [['C23.550.291.125'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.603.500', 'F04.711.513.653.574'], ['M01.060.116.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.79... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sudden unexpected death in an adult patient with endocardial cushion defect. | A 50-year-old male died following a road traffic accident. Postmortem examination revealed that the injuries caused by the accident did not seem to have caused his death. A large ostium primum defect was found, with bridging leaflets attached to the interventricular septum. In this article, we present a case of sudden ... | ['Accidents, Traffic', 'Death, Sudden, Cardiac', 'Endocardial Cushion Defects', 'Humans', 'Male', 'Middle Aged'] | 15,363,756 | [['N06.850.135.392'], ['C14.280.383.220', 'C23.550.260.322.250'], ['C14.240.400.560.350', 'C14.280.400.560.350', 'C16.131.240.400.560.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Plasma radioiron kinetics in man: explanation for the effect of plasma iron concentration. | The plasma iron turnover was measured in 19 normal subjects. A correlation was found between plasma iron concentration and plasma iron turnover. In addition to the turnover of 55Fe at normal plasma iron concentration (predominantly monoferric transferrin), a second turnover in which the labeled plasma was saturated wit... | ['Adult', 'Blood Volume', 'Female', 'Humans', 'Iron', 'Iron Radioisotopes', 'Kinetics', 'Male', 'Transferrin'] | 274,740 | [['M01.060.116'], ['G09.188.130', 'G09.330.380.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.268.556.412.500.498', 'D01.268.956.287.500.498', 'D01.496.473.498', 'D01.496.749.514', 'D01.552.544.412.500.498'], ['G01.374.661', 'G02.111.490'], ['D12... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spectrophotometric quantitative analysis of the main hemoglobin derivatives. | A spectrophotometric multiwavelength method for the simultaneous determination of the main hemoglobin derivatives including oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, and methemoglobin has been developed. The choice of analytical wavelengths was made by the methods of information factors and linear programming.... | ['Carboxyhemoglobin', 'Hemoglobins', 'Humans', 'Hydrogen-Ion Concentration', 'Least-Squares Analysis', 'Male', 'Methemoglobin', 'Oxyhemoglobins', 'Smoking', 'Software', 'Spectrophotometry'] | 9,864,449 | [['D12.776.124.400.141', 'D12.776.422.316.762.149'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['D12.776.124.400.599', 'D12.776.422.316.762.571'], ['D12.776.124.400.707', 'D12.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Three-dimensional Mammary Epithelial Cell Morphogenesis Model for Analysis of TGF? Signaling. | Culturing mammary epithelial cells in laminin-rich extracellular matrices (three dimensional or 3D culture) offers significant advantages over that in the conventional two-dimensional (2D) tissue culture system in that it takes into considetation the impact of extracellular matrix (ECM) microenvironment on the prolifer... | ['Acinar Cells', 'Cell Culture Techniques', 'Cell Differentiation', 'Cell Line, Tumor', 'Cell Proliferation', 'Collagen', 'Drug Combinations', 'Epithelial Cells', 'Epithelial-Mesenchymal Transition', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Laminin', 'Mammary Glands, Human', 'Morphogenesis', 'Proteoglycan... | 26,520,121 | [['A11.031'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D26.310'], ['A11.436'], ['G04.356.500'], ['E01.370.225.500.607.512.240.310', 'E01.370.225... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dysfunctional vestibular system causes a blood pressure drop in astronauts returning from space. | It is a challenge for the human body to maintain stable blood pressure while standing. The body's failure to do so can lead to dizziness or even fainting. For decades it has been postulated that the vestibular organ can prevent a drop in pressure during a position change--supposedly mediated by reflexes to the cardiova... | ['Adult', 'Astronauts', 'Blood Pressure', 'Cardiovascular System', 'Humans', 'Male', 'Middle Aged', 'Posture', 'Space Flight', 'Vestibule, Labyrinth', 'Vision, Ocular'] | 26,671,177 | [['M01.060.116'], ['M01.526.173'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G11.427.695'], ['J01.937.285.850'], ['A09.246.300.909'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Short-term results of total hip replacements performed by visiting surgeons at an NHS treatment centre. | Between December 2004 and June 2006, 136 patients (156 total hip replacements), were sent from the waiting list of the Cardiff Vale NHS Trust to the NHS Treatment Centre, Weston-super-Mare, in an attempt to reduce the waiting time for total hip replacement. Because of concerns about their outcome, each patient was cont... | ['Acetabulum', 'Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'England', 'Female', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'National Health Programs', 'Radiography', 'Referral and Consultation', 'Reoperation', 'Treatment Outcome', 'Waiting Lists', 'Workload'] | 19,721,039 | [['A02.835.232.043.825.108'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['Z01.542.363.300'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N03.349.550'], ['E01.370.350.700'], ['N04.452.... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Modeling human papillomavirus vaccine effectiveness: quantifying the impact of parameter uncertainty. | The development of models is based on assumptions, which inevitably embed a level of uncertainty. Quantifying such uncertainty is particularly important when modeling human papillomavirus (HPV) vaccine effectiveness; the natural history of infection and disease is complex, and age- and type-specific data remain scarce ... | ['Adolescent', 'Adult', 'Carcinoma, Squamous Cell', 'Child', 'Computer Simulation', 'Female', 'Humans', 'Middle Aged', 'Models, Theoretical', 'Papillomaviridae', 'Papillomavirus Infections', 'Papillomavirus Vaccines', 'Uncertainty', 'Uterine Cervical Neoplasms', 'Viral Vaccines'] | 17,276,976 | [['M01.060.057'], ['M01.060.116'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['M01.060.406'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599'], ['B04.280.210.655', 'B04.613.204.655'], ['C01.925.256.650', 'C01.925.928.725'], ['D20.215.894.899.498'], ['E05.318.740.6... | ['Named Groups [M]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Distinguishing rate-limiting electron versus H-atom transfers in Cu2O2-mediated oxidative N-dealkylations: application of inter- versus intramolecular kinetic isotope effects. | Copper-dioxygen adducts are important biological oxidants. To gain a better understanding of the underlying chemistries of such species, we report on a series of Cu2II-O2 complexes, [{CuII(MePY2)R'}2(O2)](B(C6F5)4)2 (1R') (where (MePY2)R' is a 4-pyridyl substituted bis[2-(2-(4-R'-pyridyl)ethyl]methylamine; R' = H, MeO,... | ['Alkylation', 'Aniline Compounds', 'Copper', 'Electrons', 'Hydrogen', 'Kinetics', 'Oxidation-Reduction', 'Oxygen'] | 14,558,790 | [['G02.111.035', 'G02.607.094', 'G03.059'], ['D02.092.146'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G01.249.335', 'G01.358.500.750'], ['D01.268.406', 'D01.362.340'], ['G01.374.661', 'G02.111.490'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cross-sectional evaluation of bone metabolism in men. | There are relatively few data concerning age-related changes of bone turnover in men. The aim of the study was to evaluate age-related changes of the levels of serum and urinary biochemical markers of bone metabolism in a large cohort of 934 men aged 19-85 years and to investigate their association with bone mineral de... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Alkaline Phosphatase', 'Amino Acids', 'Biomarkers', 'Bone Density', 'Bone Resorption', 'Bone and Bones', 'Collagen', 'Collagen Type I', 'Cross-Sectional Studies', 'Humans', 'Male', 'Middle Aged', 'Osteocalcin', 'Peptides', 'Phosphopeptides', 'Procollagen'] | 11,547,833 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['D08.811.277.352.650.035'], ['D12.125'], ['D23.101'], ['G11.427.100'], ['C05.116.264', 'G11.427.213.150'], ['A02.835.232', 'A10.165.265'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.10... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chlorophyll fluorescence tracks seasonal variations of photosynthesis from leaf to canopy in a temperate forest. | Accurate estimation of terrestrial gross primary productivity (GPP) remains a challenge despite its importance in the global carbon cycle. Chlorophyll fluorescence (ChlF) has been recently adopted to understand photosynthesis and its response to the environment, particularly with remote sensing data. However, it remain... | ['Chlorophyll', 'Ecosystem', 'Environmental Monitoring', 'Fluorescence', 'Forests', 'Massachusetts', 'Photosynthesis', 'Plant Leaves', 'Seasons'] | 27,976,474 | [['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G16.500.275.157.437', 'N06.230.124.343'], ['Z01.107.567.875.550.510'], ['G02.111.158.937', 'G02.111.669.700', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Sex bias in psychological research. Progress or complacency? | A total of 4,952 articles published in 1970, 1975, 1980, 1985, and 1990 in the areas of developmental, clinical, physiological, and social psychology were reviewed for the purpose of assessing various indicators of sexism in human psychological research. Significant changes in sex of first author, sex of participants, ... | ['Female', 'Gender Identity', 'Humans', 'Prejudice', 'Psychology', 'Publishing', 'Research', 'United States', "Women's Rights"] | 1,562,109 | [['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.813.550', 'F01.829.595'], ['F04.096.628'], ['L01.737'], ['H01.770.644'], ['Z01.107.567.875'], ['I01.880.604.473.850', 'N03.706.437.850']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Interferon treatment inhibits glycosylation of a viral protein. | Earlier, we reported a 30-200-fold reduction in the yield of infectious vesicular stomatitis virus (VSV) released from L cells treated with 10-30 reference units ml-1 of interferon (IFN); however, in these cultures virus particle production, as measured by VSV particle-associated viral RNA, virus nucleocapsid protein a... | ['Dolichol Phosphates', 'Glucosamine', 'Glycoproteins', 'Interferons', 'Tunicamycin', 'Uridine Diphosphate N-Acetylglucosamine', 'Vesicular stomatitis Indiana virus', 'Viral Proteins', 'Virus Replication'] | 6,159,539 | [['D02.033.318.250', 'D02.033.415.230.250', 'D02.455.849.366.250', 'D02.455.849.690.250', 'D02.705.400.725.200', 'D10.289.230.250'], ['D09.067.342.531'], ['D09.400.430', 'D12.776.395'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['D03.383.742.680.725', 'D13.570.685.725'], ['D03.383.742.686.850.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of HLA alleles in response to treatment with pegylated interferon-alpha and ribavirin in patients with chronic hepatitis C. | The objective of this study was to analyse the possible role of HLA polymorphism of chronically infected hepatitis C virus patients in the response outcome to treatment with pegylated interferon-alpha plus ribavirin. To that end, 144 Brazilian patients infected only with genotype 1 of the virus were treated with pegyla... | ['Adult', 'Alleles', 'Drug Therapy, Combination', 'Female', 'Follow-Up Studies', 'Genes, MHC Class I', 'Genes, MHC Class II', 'Genotype', 'HLA-DRB1 Chains', 'Hepacivirus', 'Hepatitis C, Chronic', 'Histocompatibility Testing', 'Humans', 'Interferon-alpha', 'Male', 'Middle Aged', 'RNA, Viral', 'Recurrence', 'Ribavirin', ... | 22,284,614 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['E02.319.310'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.360.340.024.340.610.595', 'G05.360.340.024.380.500.595', 'G12.500.500.595'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gene therapy with cytokine-transfected xenogeneic cells in metastatic tumors. | On the basis of compelling preclinical data in cats and dogs we initiated a clinical gene therapy study in nine patients with advanced solid tumors using xenogeneic fibroblasts secreting human IL-2 (Vero-IL-2 cells). Cohorts of three successive patients with tumors accessible to CT- or ultrasound-guided injection were ... | ['Adult', 'Aged', 'Animals', 'Antigens, CD', 'Cats', 'Chlorocebus aethiops', 'Clinical Protocols', 'Cytokines', 'Dogs', 'Female', 'Genetic Therapy', 'Humans', 'Immunotherapy', 'Interleukin-2', 'Male', 'Middle Aged', 'Neoplasms', 'Transfection', 'Transplantation, Heterologous', 'Vero Cells'] | 10,026,923 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E02.183', 'N05.715.360.330.125'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.7... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Activation of protein kinase C (PKC) by 3,4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter. | This report further characterizes the intermediate metabolic effects of the psychotropic amphetamine derivative, 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy"), on the activity of second messenger-dependent kinases. Previous work has demonstrated that two injections of MDMA (20 mg/kg) elicits a prolonged translo... | ['Animals', 'Binding Sites', 'Brain', 'Brain Stem', 'Carrier Proteins', 'Cerebral Cortex', 'Enzyme Activation', 'Female', 'Fluoxetine', 'Hippocampus', 'Ketanserin', 'Membrane Glycoproteins', 'Membrane Transport Proteins', 'N-Methyl-3,4-methylenedioxyamphetamine', 'Nerve Tissue Proteins', 'Phorbol 12,13-Dibutyrate', 'Pr... | 9,272,479 | [['B01.050'], ['G02.111.570.120'], ['A08.186.211'], ['A08.186.211.132'], ['D12.776.157'], ['A08.186.211.200.885.287.500'], ['G02.111.263', 'G03.328'], ['D02.092.831.280'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D03.383.621.365', 'D03.633.100.786.830.333'], ['D12.776.395.550', 'D12.776.543.550'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infiltration patterns in monoclonal plasma cell disorders: correlation of magnetic resonance imaging with matched bone marrow histology. | OBJECTIVES: To investigate how plasma cell infiltration patterns detected by MRI match the plasma cell distribution in bone marrow biopsy.METHODS: We assessed 50 patients with monoclonal plasma cell disorders of all clinical stages. MRI infiltration pattern was compared with matched BM histology from the same anatomic ... | ['Adult', 'Aged', 'Bone Marrow', 'Bone Marrow Cells', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Paraproteinemias', 'Plasma Cells', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Statistics as Topic'] | 24,725,673 | [['M01.060.116'], ['M01.060.116.100'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C15.378.147.780', 'C20.683.780'], ['A11.063.438.725', 'A11.118.637.555.5... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Identifying the impact of government targets on waiting times in the NHS. | Waiting times for elective surgery are a key issue for the NHS. The principal policy response in the English NHS has been to introduce maximum waiting time targets against which performance is measured and rewarded. The aim of this paper is to identify the effect of government targets on the distribution of waiting tim... | ['Efficiency, Organizational', 'Elective Surgical Procedures', 'Female', 'Hospitals, Public', 'Humans', 'Male', 'Patient Admission', 'State Medicine', 'Survival Analysis', 'Time Factors', 'United Kingdom', 'Waiting Lists'] | 19,938,438 | [['N04.452.209.500'], ['E04.249'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.600', 'N02.421.585.400.600'], ['N03.349.550.902', 'N03.858'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['G01.910.857'], ['Z01.542.363'], ['N04.452.095.738']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Characterization of two crustin antimicrobial peptides from the freshwater crayfish Pacifastacus leniusculus. | The two bacteria-induced crustin genes, Plcrustin1 and Plcrustin2, previously found in the hemocyte cDNA library of Pacifastacus leniusculus, contain the open reading frames of 357 bp encoding a putative protein of 118 amino acid residues and 330 bp encoding a putative protein of 109 amino acid residues, respectively. ... | ['Amino Acid Sequence', 'Animals', 'Anti-Infective Agents', 'Antimicrobial Cationic Peptides', 'Astacoidea', 'Electrophoresis, Polyacrylamide Gel', 'Hemocytes', 'Microbial Sensitivity Tests', 'Recombinant Proteins', 'Serine Proteinase Inhibitors'] | 20,371,367 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.122'], ['D12.644.050', 'D12.776.543.695.054'], ['B01.050.500.131.365.190.070'], ['E05.196.401.402', 'E05.301.300.319'], ['A11.118.480', 'A15.145.229.480'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D12.776.828'], ['D27.505.51... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fate of histone messenger RNA in synchronized HeLa cells in the absence of initiation of protein synthesis. | The fate of cytoplasmic histone mRNA was studied under conditions in which initiation of protein synthesis in synchronized HeLa cells is S phase was blocked by increasing the osmolarity of the growth medium with NaCl. In contrast to the interruption of DNA replication with hydroxyurea, which results in an exponential d... | ['Cell Division', 'Centrifugation, Density Gradient', 'DNA Replication', 'Dactinomycin', 'HeLa Cells', 'Histones', 'Kinetics', 'Mitosis', 'Molecular Weight', 'Neoplasm Proteins', 'Polyribosomes', 'Protein Biosynthesis', 'RNA, Messenger', 'Ribosomes', 'Time Factors', 'Transcription, Genetic'] | 837,922 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E05.181.724.336', 'E05.196.941.336'], ['G02.111.225', 'G05.226'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Transfection of HL-60 cells by Venus lentiviral vector]. | In order to study the potential of Venus, lentiviral vector, applied to acute myeloid leukemia, the recombinant vector Venus-C3aR was transfected into 293T packing cells by DNA-calcium phosphate coprecipitation. All virus stocks were collected and transfected into HL-60, the GFP expression in HL-60 cells was measured b... | ['Genetic Vectors', 'HL-60 Cells', 'Humans', 'Lentivirus', 'Transfection'] | 23,815,901 | [['G05.360.337'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.650.589'], ['E05.393.350.810', 'G05.728.860']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relation between popularity and achievement: a longitudinal test of the lateral transmission of value hypothesis. | Data from a longitudinal study of school desegregation were used to examine the relation between normative social influence processes and academic achievement in order to test theoretical models of how school desegregation produces benefit. Subjects were white, Mexican-American, and black elementary school children who... | ['Achievement', 'African Americans', 'California', 'Child', 'Ethnic Groups', 'Female', 'Humans', 'Male', 'Models, Psychological', 'Prejudice', 'Social Desirability', 'Social Values'] | 3,783,423 | [['F01.658.059', 'F02.784.629.054'], ['M01.686.508.100.100', 'M01.686.754.100'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['M01.060.406'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F01.145.813.550', 'F01.829.595'], ['F01.145.813.628'], ['F01.829.8... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Diabetes in adolescent patients: diagnostic dilemmas. | The classification of diabetes mellitus by types (1 or 2), or by age of onset (juvenile or adult), helps to clarify many aspects of pathophysiology, prognosis, and therapy. However, less-commonly encountered patients, presenting in childhood or adolescence, may not fit neatly into one or the other group. These include ... | ['Adolescent', 'Child', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Humans'] | 11,338,217 | [['M01.060.057'], ['M01.060.406'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Predictors of Unplanned Reoperation After Operative Treatment of Pelvic Ring Injuries. | OBJECTIVES: To evaluate the incidence of unplanned reoperations after pelvic ring injuries and to develop a risk prediction model.DESIGN: Retrospective review.SETTING: Level I Trauma Center.PATIENTS: The medical records of 913 patients (644 male and 269 female patients; mean age, 39 years; age range, 16-89 years) with ... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Female', 'Fracture Fixation, Internal', 'Fracture Healing', 'Fractures, Bone', 'Humans', 'Incidence', 'Injury Severity Score', 'Kaplan-Meier Estimate', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Pelvic Bones', 'Postoperati... | 29,634,600 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.555.300.300'], ['G16.762.891.500'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The changes of palate cleft gap of complete unilateral cleft lip and palate infants before and after presurgical orthodontic and cheiloplasty]. | OBJECTIVE: To study the changes of palate cleft gap of complete unilateral cleft lip and palate (UCLP) infants before and after presurgical orthodontic and cheiloplasty.METHODS: The sample consisted of 18 complete UCLP infants who were treated using presurgical nasoalveolar molding (PNAM) appliance and cheiloplasty. Th... | ['Cleft Lip', 'Cleft Palate', 'Humans', 'Infant', 'Lip', 'Nose', 'Preoperative Care'] | 21,776,854 | [['C07.465.409.225', 'C07.465.525.164', 'C07.650.525.164', 'C16.131.850.525.164'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.500.460.185', 'C07.650.525.185', 'C16.131.621.207.540.460.185', 'C16.131.850.500.460.185', 'C16.131.850.525.185'], ['B01.050.150.900.649.313.98... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Asthma in the Army: 1985-1996. | Based on comparison between data obtained on medical discharges from the Army due to asthma for 1985 and for 1994-1995, this study shows that the current Army policy on asthma and recruiting is effective but could be improved. Plans aimed at improving the current screening programme are introduced. | ['Adolescent', 'Adult', 'Asthma', 'Exercise Test', 'Female', 'Humans', 'Male', 'Mass Screening', 'Military Medicine', 'Military Personnel', 'Personnel Selection', 'Time Factors', 'United Kingdom'] | 10,216,844 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Isolation, expression, and nucleotide sequence of the sod gene from Porphyromonas gingivalis. | The sod gene coding for the Mn/Fe-dependent superoxide dismutase (SOD) enzyme has been isolated on a 5.9-kb DNA fragment from Porphyromonas gingivalis ATCC 53977. SOD activity can be expressed from the P. gingivalis fragment and from a subcloned fragment in Escherichia coli. However, the enzyme does not appear to be ex... | ['Amino Acid Sequence', 'Bacteroides', 'Base Sequence', 'Escherichia coli', 'Gene Expression', 'Genes, Bacterial', 'Molecular Sequence Data', 'Superoxide Dismutase'] | 1,840,572 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.440.080.094.152', 'B03.440.425.410.194.152'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['L01.45... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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