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Biomarkers of cardiac dysfunction and mortality from community-acquired pneumonia in adults. | BACKGROUND: Cardiac dysfunction is common in acute respiratory diseases and may influence prognosis. We hypothesised that blood levels of N-terminal B-type natriuretic peptide (NT-proBNP) and high-sensitivity Troponin T would predict mortality in adults with community-acquired pneumonia.METHODS AND FINDINGS: A prospect... | ['Aged', 'Aged, 80 and over', 'Biomarkers', 'Cohort Studies', 'Community-Acquired Infections', 'Female', 'Heart', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Pneumonia', 'ROC Curve', 'Troponin T'] | 23,667,500 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.234'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['D06.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dual use of an amplatzer device in the transcatheter embolization of a large high-flow renal arteriovenous fistula. | Embolization procedures are now considered the first-line therapy in the treatment of renal arteriovenous fistulas (AVFs). However, a risk posed by the use of these minimally invasive techniques is the migration of occluding agents into the venous and pulmonary circulations. The risk is of particular importance for lar... | ['Adult', 'Angiography', 'Arteriovenous Fistula', 'Embolization, Therapeutic', 'Equipment and Supplies', 'Foreign-Body Migration', 'Humans', 'Male', 'Renal Artery', 'Renal Veins', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 17,494,851 | [['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C14.240.850.750.147', 'C14.240.850.984.750', 'C14.907.150.125', 'C14.907.933.555', 'C16.131.240.850.750.125', 'C23.300.575.950.250'], ['E02.520.360', 'E02.926.500'], ['E07'], ['C26.392.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An in vitro study to determine the effect of Terminalia chebula extract and its formulation on Streptococcus mutans. | AIM: Many weapons are available in the arsenal of a dental professional to combat dental caries, which is almost ubiquitously present. From a public health perspective, most of these weapons are far from being an ideal drug. Hence, there is a demand for better and effective antibacterial agents. This factor stimulated ... | ['Anti-Bacterial Agents', 'Bacterial Adhesion', 'Carboxymethylcellulose Sodium', 'Cariogenic Agents', 'Cariostatic Agents', 'Chemistry, Pharmaceutical', 'Ethanol', 'Fruit', 'Glucans', 'Glycolysis', 'Humans', 'Mannitol', 'Materials Testing', 'Microbial Sensitivity Tests', 'Mouthwashes', 'Parabens', 'Phytotherapy', 'Plan... | 25,307,806 | [['D27.505.954.122.085'], ['G06.099.050'], ['D09.698.365.180.663.329'], ['D25.187', 'D27.720.102.187', 'J01.637.051.187'], ['D25.223', 'D27.505.696.706.222', 'D27.720.102.223', 'D27.720.799.113', 'J01.637.051.223'], ['H01.158.703.007', 'H01.181.466'], ['D02.033.375'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
In vitro osteogenic differentiation of adipose stem cells after lentiviral transduction with green fluorescent protein. | BACKGROUND: Adipose-derived stem cells (ASCs) have the potential to differentiate into osteogenic cells that can be seeded into scaffolds for tissue engineering for use in craniofacial bone defects. Green fluorescent protein (GFP) has been widely used as a lineage marker for mammalian cells. The use of fluorescent prot... | ['Adipose Tissue', 'Animals', 'Cell Differentiation', 'Cell Lineage', 'Cells, Cultured', 'Gelatin Sponge, Absorbable', 'Green Fluorescent Proteins', 'Humans', 'Induced Pluripotent Stem Cells', 'Kidney', 'Lentivirus', 'Luminescent Agents', 'Male', 'Osteoblasts', 'Osteocalcin', 'Osteogenesis', 'Rats', 'Rats, Sprague-Dawl... | 19,934,675 | [['A10.165.114'], ['B01.050'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A11.251'], ['E07.858.740.300'], ['D12.776.532.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['A05.810.453'], ['B04.820.650.589'], ['D27.720.47... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Use protocol to send inpatient holds upstairs. | A "full capacity" protocol requires that admitted patients being held in the ED are moved upstairs when the ED is at full capacity. Length of stay for admitted patients is reduced. Morale of ED nurses is improved. Inpatients receive better care when moved upstairs. | ['Emergency Service, Hospital', 'Guidelines as Topic', 'Humans', 'Inpatients', 'New York', 'Patient Admission', 'Patient Transfer'] | 12,733,220 | [['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['Z01.107.567.875.075.437', 'Z01.107.567.875.350.530', 'Z01.107.567.875.500.530'], ['E02.760.400.600', 'N02.421.585.400.600'], ['E02.760.169.6... | ['Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Terra firma-forme dermatosis]. | BACKGROUND: Terra firma-forme (i.e. resembling dry earth) is a condition chiefly affecting children wrongly considered as dermatosis arising out of negligence and inadequate corporal hygiene. It is in fact an acquired and asymptomatic grey-brown hyperpigmentation of the skin that persists despite normal washing with so... | ['2-Propanol', 'Acanthosis Nigricans', 'Adolescent', 'Ankle', 'Child', 'Child, Preschool', 'Comorbidity', 'Diagnosis, Differential', 'Female', 'Humans', 'Hygiene', 'Hyperpigmentation', 'Infant', 'Male', 'Neck', 'Retrospective Studies', 'Therapeutic Irrigation'] | 24,206,804 | [['D02.033.755.615'], ['C17.800.621.430.530.100'], ['M01.060.057'], ['A01.378.610.050'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.547', 'N06.850.670'], ['C17.800.621.430'], ['M01.060.703'], ['A01.598'], ['E05.318.37... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Altered behavior and alcohol tolerance in transgenic mice lacking MAO A: a comparison with effects of MAO A inhibitor clorgyline. | The influence of deficiency of monoamine oxidase A (MAO A) gene and the lack of enzyme MAO A on the behavior of transgenic mouse strain (Tg8) was studied. It was shown that MAO-A-lacking mice differed from mice of the wild-type strain C3H/HeJ (C3H) by an attenuated acoustic startle response, prepulse inhibition (PPI) w... | ['Alcohol Drinking', 'Animals', 'Anxiety', 'Central Nervous System Depressants', 'Clorgyline', 'Drug Tolerance', 'Ethanol', 'Exploratory Behavior', 'Hypothermia', 'Male', 'Mice', 'Mice, Inbred C3H', 'Mice, Transgenic', 'Monoamine Oxidase', 'Monoamine Oxidase Inhibitors', 'Motor Activity', 'Reflex, Startle', 'Sleep'] | 11,166,062 | [['F01.145.317.269'], ['B01.050'], ['F01.470.132'], ['D27.505.696.277', 'D27.505.954.427.210'], ['D02.092.831.180'], ['G07.690.773.992'], ['D02.033.375'], ['F01.145.387', 'F01.658.370'], ['C23.888.119.565'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.50... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of unesterified cholesterol on the activity of cholesteryl ester transfer protein. | Cholesteryl ester transfer protein (CETP) catalyses the transfer of cholesteryl ester from high-density lipoprotein to triacylglycerol-rich lipoproteins and the transfer of triacylglycerols in the reverse direction. The activity of CETP has been studied using a continuous fluorescence assay which measures the excimer f... | ['Carrier Proteins', 'Cholesterol', 'Cholesterol Ester Transfer Proteins', 'Cholesterol Esters', 'Emulsions', 'Glycoproteins', 'Humans', 'Kinetics', 'Male', 'Phosphatidylcholines', 'Spectrometry, Fluorescence', 'Tritium'] | 7,998,976 | [['D12.776.157'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D09.400.430.750', 'D12.776.124.197', 'D12.776.157.165', 'D12.776.395.199'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['D20.280.260', 'D26.255.165.260'], ['D09.400.430', 'D12.776.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Significance of parasitic blood supply in malignant retroperitoneal tumours (author's transl)]. | Twenty-one neoplastic retroperitoneal tumours- in particular Wilm's tumours and neuroblastomas of the suprarenal glands in children - are analyzed angiographically and the significance of the parasitic blood supply evaluated. More than half of the tumours had penetrating or perforating vessels, but in only 50% there we... | ['Adolescent', 'Adrenal Gland Neoplasms', 'Adult', 'Angiography', 'Child', 'Child, Preschool', 'Ganglioneuroma', 'Humans', 'Infant', 'Kidney Neoplasms', 'Retroperitoneal Neoplasms', 'Wilms Tumor'] | 6,261,432 | [['M01.060.057'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['M01.060.406'], ['M01.060.406.448'], ['C04.557.465.625.600.355', 'C04.557.470.670.355', 'C04.557.580.625.600.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
100 consecutive thyroidectomies performed by a single surgeon in an upstate South Carolina teaching hospital: an outcome analysis. | An experienced surgeon in a community hospital with surgical resident participation can perform thyroid surgery safely. An outcome analysis of 100 consecutive thyroidectomies showed a 1.2% incidence of permanent recurrent nerve injury and no cases of permanent hypo-parathyroidism. Temporary hypocalcemia was common (in ... | ['Adolescent', 'Adult', 'Aged', 'Benchmarking', 'Female', 'Hospitals, Community', 'Humans', 'Hyperthyroidism', 'Internship and Residency', 'Male', 'Medical Audit', 'Middle Aged', 'Outcome Assessment, Health Care', 'Postoperative Complications', 'Risk Factors', 'Safety', 'South Carolina', 'Thyroidectomy', 'Utilization R... | 17,703,844 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['N02.278.421.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['N04.761.700.250.500', 'N05.700... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[Localization of Chinese acupuncture-moxibustion in the United States: the openness of modern acupuncture-moxibustion system]. | The internationalization of Chinese acupuncture-moxibustion is inevitably accompanied by the localization of acupuncture-moxibustion. The localization of acupuncture-moxibustion will inevitably promote the diversified development of acupuncture-moxibustion technique and theory, which fully demonstrates the openness of ... | ['Acupuncture Therapy', 'Moxibustion', 'United States'] | 31,930,905 | [['E02.190.044'], ['E02.190.044.588'], ['Z01.107.567.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Isolation of mouse reticulocyte globin messenger ribonucleoprotein by affinity chromatography using oligo(T)-cellulose. | Mouse globin messenger ribonucleoprotein (mRNP) has been isolated from reticulocyte polysomes by affinity chromatography to oligo(T)-cellulose, using a procedure modified from that of Lindberg and Sundquist. The messenger RNA and protein moieties fo the mRNP are indistinguishable from those isolated by less rapid techn... | ['Animals', 'Chromatography, Affinity', 'Electrophoresis, Polyacrylamide Gel', 'Globins', 'Mice', 'Nucleoproteins', 'Polyribosomes', 'RNA, Messenger', 'Reticulocytes', 'Ribonucleoproteins'] | 1,052,540 | [['B01.050'], ['E05.196.181.400.170'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.422.316'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.664'], ['A11.284.430.214.190.875.811.740'], ['D13.444.735.544'], ['A11.118.290.760', 'A11.148.790', 'A11.443.240.665', 'A15.145.229.334.760', 'A15.378.316.790'], ['D... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanical and electrical properties of smooth muscle cells and their regulations by endothelium-derived factors in the guinea pig coronary artery. | Effects of high K+, acetylcholine (ACh), 9,11-epithio-11,12-methanothromboxane A2 (STA2), thrombin and endothelin were investigated on smooth muscles of the guinea pig coronary artery in intact and endothelium-denuded tissues. In intact tissues, ACh transiently inhibited but ATP produced maintained inhibition of the ST... | ['Acetylcholine', 'Adenosine Triphosphate', 'Animals', 'Arteries', 'Coronary Vessels', 'Endothelins', 'Female', 'Guinea Pigs', 'Male', 'Muscle Contraction', 'Muscle, Smooth', 'Nitric Oxide'] | 2,087,000 | [['D02.092.211.111'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A07.015.114'], ['A07.015.114.269', 'A07.015.908.194'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['B01.050.150.900.649.313.992.550'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['D01.33... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence that L-carnitine and selenium supplementation reduces oxidative stress in phenylketonuric patients. | It is well established that the involvement of reactive species in the pathophysiology of several neurological diseases, including phenylketonuria (PKU), a metabolic genetic disorder biochemically characterized by elevated levels of phenylalanine (Phe). In previous studies, we verified that PKU patients (treated with a... | ['Adolescent', 'Antioxidants', 'Carnitine', 'Dietary Supplements', 'Humans', 'Oxidative Stress', 'Phenylketonurias', 'Reactive Oxygen Species', 'Selenium', 'Thiobarbituric Acid Reactive Substances', 'Young Adult'] | 21,191,647 | [['M01.060.057'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.092.877.883.099'], ['G07.203.300.456', 'J02.500.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.673', 'G07.775.750'], ['C10.228.140.163.100.687', 'C16.320.565.100.766', 'C16.320.565.189.687', 'C18.452.132.100.687', 'C18... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Salvage Completion Pancreatectomies as Damage Control for Post-pancreatic Surgery Complications: A Single-Center Retrospective Analysis. | BACKGROUND: Post-pancreatic surgical morbidity is frequent but often manageable by less invasive means than re-operation. Yet, some complications can become hazardous and life threatening. Herein, the results of a completion pancreatectomy (CP) to cope with severe post-operative pancreatic fistulas (POPF) and bleeding ... | ['Aged', 'Aged, 80 and over', 'Anastomotic Leak', 'Female', 'Hospital Mortality', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Pancreas', 'Pancreatectomy', 'Pancreatic Fistula', 'Pancreatic Neoplasms', 'Pancreaticojejunostomy', 'Pancreatitis', 'Postoperative Complications', 'Postoperative Hemorrhage', 'Reoperati... | 25,651,954 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.767.071'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['A03.734'], ['E04.210.7... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Selective cytotoxicity of withaphysalins in myeloid leukemia cell lines versus peripheral blood mononuclear cells. | Withaphysalins are C(28)-steroidal lactones structurally based on the ergostane skeleton that possess antiproliferative activity against tumor cell lines. In the present study, the antileukemic actvity of withaphysalin O (1), M (2), and N (3) isolated from Acnistus arborescens, against two leukemic cell lines, HL-60 an... | ['Apoptosis', 'Caspase 3', 'Caspases', 'Cell Proliferation', 'DNA Replication', 'Ergosterol', 'HL-60 Cells', 'Humans', 'Leukemia, Myeloid', 'Leukocytes, Mononuclear', 'Secosteroids'] | 16,824,549 | [['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Poor glycemic control is a strong predictor of postoperative morbidity and mortality in patients undergoing vascular surgery. | OBJECTIVE: Hyperglycemia is a common occurrence in patients undergoing cardiovascular surgery. It has been identified in several surgical cohorts that improved perioperative glycemic control reduced postoperative morbidity and mortality. A significant portion of the population with peripheral arterial disease suffers f... | ['Aged', 'Biomarkers', 'Blood Glucose', 'Databases, Factual', 'Female', 'Humans', 'Hyperglycemia', 'Hypoglycemic Agents', 'Male', 'Middle Aged', 'Patient Readmission', 'Reoperation', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Time Factors', 'Treatment Outcome', 'Vascular Surgical Procedures'] | 30,459,015 | [['M01.060.116.100'], ['D23.101'], ['D09.947.875.359.448.500'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['D27.505.696.422'], ['M01.060.116.630'], ['E02.760.400.620', 'N02.421.585.400.620'], ['E04.690'], ['E05.318.372.500.500.500', 'E05.31... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The diagnostic performance of a novel ELISA for human CTP (Cochlin-tomoprotein) to detect perilymph leakage. | Perilymphatic fistula is defined as an abnormal communication between the perilymph-filled space and the middle ear, or cranial spaces. The manifestations include a broad spectrum of neuro-otological symptoms such as hearing loss, vertigo/dizziness, disequilibrium, aural fullness, tinnitus, and cognitive dysfunction. B... | ['Blotting, Western', 'Enzyme-Linked Immunosorbent Assay', 'Extracellular Matrix Proteins', 'Humans', 'Perilymph'] | 29,377,910 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.270.517.678']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the effect of glycerol and triamcinolone acetonide on cumulative skin irritation in a randomized trial. | BACKGROUND: So-called anti-irritants are added to cosmetic formulations because of their alleged beneficial effect on irritated skin. Documentation for these claims is often limited. However, glycerol has shown anti-irritant properties in experimentally induced irritation from sodium lauryl sulfate and nonanoic acid (N... | ['Adult', 'Anti-Inflammatory Agents', 'Colorimetry', 'Cosmetics', 'Cryoprotective Agents', 'Double-Blind Method', 'Female', 'Glycerol', 'Humans', 'Male', 'Skin', 'Skin Irritancy Tests', 'Triamcinolone Acetonide', 'Water Loss, Insensible'] | 17,156,893 | [['M01.060.116'], ['D27.505.954.158'], ['E05.196.922.250'], ['D27.720.269', 'J01.516.213'], ['D27.505.696.706.320', 'D27.720.799.180'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D02.033.800.875.500', 'D09.853.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A17... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Preventing infant deaths: a descriptive study of one high-risk neighborhood. | This study examines whether 72 infant deaths in one urban neighborhood in one year could have been prevented and if so, how. The neighborhood was targeted for a Maternal and Child Health Block Grant demonstration project because of its combination of low income and high rates of unemployment, teenage births, and infant... | ['Child Health Services', 'Decision Trees', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Louisiana', 'Maternal Health Services', 'Preventive Health Services', 'Risk Factors', 'Socioeconomic Factors', 'Urban Population'] | 3,452,359 | [['N02.421.143.130'], ['G17.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], ['M01.060.703.520'], ['Z01.107.567.875.750.480'], ['N02.421.143.620', 'N02.421.800.500'], ['N02.421.7... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The purinergic receptor P2X7 role in control of Dengue virus-2 infection and cytokine/chemokine production in infected human monocytes. | Purinergic signaling has a crucial role in intracellular pathogen elimination. The P2X7 purinergic receptor (P2X7R), once activated by ATP, leads to pro-inflammatory responses including reactive oxygen species production. ATP can be released by injured cells, as endogenous danger signals. Dengue fever may evolve to a s... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'Adenosine Triphosphate', 'Cells, Cultured', 'Chemokines', 'Cytokines', 'Dengue', 'Dengue Virus', 'Humans', 'Monocytes', 'Nitric Oxide', 'Receptors, Purinergic P2X7', 'Viral Load'] | 26,969,484 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.251'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C01.92... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The utility of thermistor attached tracheal tube for pediatric patients in cardiac surgery]. | During cardiac surgery, esophageal, rectal, or bladder temperature is usually monitored as an index of core temperature; however, these methods are invasive, and often inconsistently reflect the central body temperature, especially in pediatric patients. The purpose of this study was to evaluate the utility of tracheal... | ['Anesthesia, General', 'Biosensing Techniques', 'Body Temperature', 'Cardiac Surgical Procedures', 'Cardiopulmonary Bypass', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Intubation, Intratracheal', 'Male', 'Monitoring, Physiologic'] | 7,474,320 | [['E03.155.197'], ['E05.601.043'], ['E01.370.600.875.374', 'G07.110'], ['E04.100.376', 'E04.928.220'], ['E04.292.413'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E01.370.520']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Different effects of depolarization and muscarinic stimulation on the Ca2+/force relationship during the contraction-relaxation cycle in the guinea pig ileum. | The effects of K+ depolarization and of the muscarinic agonist carbachol on [Ca2+]i and force were investigated in smooth muscle sheets of the longitudinal layer of the ileum loaded with Fura-2. K(+)-rich solutions increased [Ca2+]i and force to an initial peak value, which was determined by the concentration of [K+]o.... | ['Animals', 'Calcium', 'Carbachol', 'Guinea Pigs', 'Ileum', 'Muscle Contraction', 'Muscle Relaxation', 'Muscle, Smooth', 'Potassium', 'Receptors, Muscarinic'] | 2,352,839 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['B01.050.150.900.649.313.992.550'], ['A03.556.124.684.249', 'A03.556.249.124'], ['G11.427.494'], ['G11.427.494.554'], ['A02.633.570', 'A10.690.467'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phoneme frequency effects in jargon aphasia: a phonological investigation of nonword errors. | This study investigates the nonwords produced by a jargon speaker, LT. Despite presenting with severe neologistic jargon, LT can produce discrete responses in picture naming tasks thus allowing the properties of his jargon to be investigated. This ability was exploited in two naming tasks. The first showed that LT's no... | ['Aged', 'Aged, 80 and over', 'Aphasia, Wernicke', 'Humans', 'Male', 'Periodicity', 'Phonetics', 'Severity of Illness Index', 'Vocabulary'] | 12,681,351 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.597.606.150.500.800.100.166', 'C23.888.592.604.150.500.800.100.166'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.910.645', 'G07.180.562'], ['L01.559.598.518'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells. | The development of germ cells is a highly ordered process that begins during fetal growth and is completed in the adult. Epigenetic modifications that occur in germ cells are important for germ cell function and for post-fertilization embryonic development. We have previously shown that male germ cells in the adult mou... | ['Animals', 'Base Sequence', 'CpG Islands', 'DNA Methylation', 'DNA Primers', 'Epigenesis, Genetic', 'Gene Expression Regulation, Developmental', 'Genome', 'Genomic Imprinting', 'Male', 'Meiosis', 'Mice', 'Mice, Inbred C57BL', 'Repetitive Sequences, Nucleic Acid', 'Spermatocytes', 'Spermatogenesis', 'Spermatogonia'] | 17,559,830 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.203'], ['G05.308.310'], ['G05.36... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prolonged pertussis toxin treatment affects morphine's action on tuberoinfundibular dopaminergic neuron activity and on prolactin secretion. | The effects of pertussis toxin (PTX) pretreatment on basal and morphine-affected changes of tuberoinfundibular dopaminergic (TIDA) neuron activity and serum prolactin level were tested in this study. Adult female Sprague-Dawley rats, ovariectomized and treated with a long-acting estrogen (polyestradiol phosphate, 0.1 m... | ['3,4-Dihydroxyphenylacetic Acid', 'Animals', 'Cerebral Ventricles', 'Delayed-Action Preparations', 'Dopamine', 'Drug Interactions', 'Estradiol', 'Female', 'Hypothalamus, Middle', 'Injections, Intraventricular', 'Kinetics', 'Median Eminence', 'Morphine', 'Neurons', 'Ovariectomy', 'Pertussis Toxin', 'Prolactin', 'Rats',... | 8,842,396 | [['D02.241.223.601.220'], ['B01.050'], ['A08.186.211.140'], ['D26.255.210', 'E02.319.300.253'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G07.690.773.968'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['A08.186.211.180.497.352', 'A08.186.211.200.317.357.352'], ['E0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical case of the month. Mental confusion due to the administration of tramadol in a patient treated with MOAI]. | However currently less used, MAOI (monoamine-oxidase inhibitor) antidepressants have specific indications like refractory or atypical depressions. The main difficulties related to MAOI therapy consist in their potentially very dangerous interactions with certain foods on the one side, many medications on the other side... | ['Confusion', 'Drug Interactions', 'Female', 'Humans', 'Middle Aged', 'Monoamine Oxidase Inhibitors', 'Narcotics', 'Phenelzine', 'Tramadol'] | 10,686,795 | [['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['G07.690.773.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D27.505.519.389.616'], ['D27.505.696.277.600', 'D27.505.696.663.850.014.760', 'D27.505.954.427.040.550', 'D27.505.954.427.210.600'], ['D02.442.700'], ['D02.033.415.510... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multi-component synthesis of trimetallic tetranuclear clusters [Cu(L)(H(2)O)](2)Ln(H(2)O)(2)Cr(C(2)O(4))(3).12H(2)O (H(2)L = 1,4,8,11-tetraazacyclotradecane-2,3-dione, Ln(3+) = Gd, Tb and Dy). | Novel tetranuclear Cu(ii)-Ln(iii)-Cr(iii) complexes with oxamidate and oxalate bridges have been prepared using [Cu(L)], LnCl(3).6H(2)O and K(3)[Cr(ox)(3)] components (ox(2-) = oxalate) during the development of new multimetallic complexes as molecular magnets. Overall ferromagnetic properties have been observed in the... | ['Chromium', 'Coordination Complexes', 'Copper', 'Crystallography, X-Ray', 'Dysprosium', 'Gadolinium', 'Lanthanoid Series Elements', 'Magnetics', 'Molecular Conformation', 'Organometallic Compounds', 'Oxalates', 'Oxamic Acid', 'Temperature', 'Terbium'] | 20,714,551 | [['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.234', 'D02.257'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.196.309.742.225'], ['D01.268.558.362.374', 'D01.552.550.399.374'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['D01.268.558.362', 'D01.552.550.399'], ['H01.671.493'],... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of thyroid hormone on GLUT4 glucose transporter gene expression and NIDDM in rats. | Previous studies have shown that T3 coordinately stimulates GLUT4-glucose transporter messenger RNA (mRNA) and protein expression in mixed fiber-type skeletal muscle of the rat and produces a concomitant elevation in basal (noninsulin mediated) glucose uptake. The aim of the present study was to 1) determine the precis... | ['Animals', 'Diabetes Mellitus, Type 2', 'Gene Expression', 'Glucose Transporter Type 4', 'Hindlimb', 'Hyperinsulinism', 'Male', 'Monosaccharide Transport Proteins', 'Muscle Fibers, Skeletal', 'Muscle Proteins', 'Muscle, Skeletal', 'Obesity', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Rats, Zucker', 'Transcript... | 9,048,628 | [['B01.050'], ['C18.452.394.750.149', 'C19.246.300'], ['G05.297'], ['D12.776.157.530.500.500.937', 'D12.776.157.530.937.563.937', 'D12.776.543.585.500.500.937', 'D12.776.543.585.937.625.937'], ['A13.473'], ['C18.452.394.968'], ['D12.776.157.530.500', 'D12.776.543.585.500'], ['A10.690.552.500.500', 'A11.620.249'], ['D12... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Designing equivalent treatment regimens for prostate radiotherapy based on equivalent uniform dose. | The purpose of this work was to determine alternative radiotherapy (RT) regimens that are biologically equivalent to clinically proven treatments using different RT modalities or different fractionation schemes. The concept of equivalent uniform dose (EUD) is used with the linear quadratic model to determine equivalent... | ['Brachytherapy', 'Dose Fractionation, Radiation', 'Humans', 'Male', 'Models, Biological', 'Prostatic Neoplasms', 'Radiation Dosage', 'Radiotherapy', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Rectum'] | 18,039,721 | [['E02.815.150'], ['E02.815.639.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E02.815'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The dilemma of painful old os calcis fractures. | This study of 16 patients (17 amputations) draws attention to intractable pain as a rare, but not previously emphasized, sequela of os calcis fracture. The fracture remained painful despite, in many cases, exhaustive measures to relieve symptoms. The majority of patients still had pain even after amputation and revisio... | ['Adult', 'Aged', 'Amputation', 'Calcaneus', 'Fractures, Bone', 'Fractures, Closed', 'Humans', 'Male', 'Methods', 'Middle Aged', 'Pain, Intractable', 'Tarsal Bones'] | 6,861,382 | [['M01.060.116'], ['M01.060.116.100'], ['E04.555.080'], ['A02.835.232.043.300.710.300'], ['C26.404'], ['C26.404.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['C23.888.592.612.776'], ['A02.835.232.043.300.710']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk factors for fluoroquinolone resistance in Enterococcus urinary tract infections in hospitalized patients. | Past studies exploring risk factors for fluoroquinolone (FQ) resistance in urinary tract infections (UTIs) focused only on UTIs caused by Gram-negative pathogens. The epidemiology of FQ resistance in enterococcal UTIs has not been studied. We conducted a case-control study at two medical centres within the University o... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Case-Control Studies', 'Chi-Square Distribution', 'Cross Infection', 'Drug Resistance, Microbial', 'Enterococcus', 'Female', 'Fluoroquinolones', 'Gram-Positive Bacterial Infections', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Risk Fa... | 20,696,087 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C01.248', 'C23.550.291.875.500'], ['G06.225', 'G07.690.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
-765 g>c polymorphism of the cox-2 gene and gastric cancer risk in Brazilian population. | CONTEXT: Genomic alterations play important roles in gastric cancer carcinogenesis. Cyclooxygenases (COX) are important enzymes in the maintenance of mucosal integrity and in pathological processes, mainly in inflammation and cancer. The -765G>C COX-2 polymorphism has been implicated in gastric cancer risk.OBJECTIVES: ... | ['Case-Control Studies', 'Cyclooxygenase 2', 'Female', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Restriction Fragment Length', 'Polymorphism, Single Nucleotide', 'Risk Factors', 'Stomach Neoplasms'] | 25,003,256 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D08.811.600.720.750'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.795.595'], ['G05.365.795.598'], ['E05.318.740.600.800.725', 'N05.715.350.200.700',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fixed digital contractures revealing light-chain amyloidosis. | Among the many clinical manifestations of light-chain (AL) amyloidosis, musculoskeletal involvement is rarely reported. We describe the case of a 72-year-old woman who was referred to our rheumatology department for fixed flexion contractures of the fingers that developed concomitantly with a decline in general health.... | ['Aged', 'Amyloidosis', 'Contracture', 'Dyspnea', 'Female', 'Fluorodeoxyglucose F18', 'Hand Bones', 'Humans', 'Immunoglobulin Light Chains', 'Immunoglobulin kappa-Chains', 'Macroglossia', 'Radiography', 'Radioisotopes', 'Shoulder Joint'] | 19,800,832 | [['M01.060.116.100'], ['C18.452.845.500'], ['C05.550.323', 'C05.651.197'], ['C08.618.326', 'C23.888.852.371'], ['D09.254.229.500'], ['A02.835.232.087.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.705.750', 'D12.776.124.790.651.705.750', 'D12.776.377.715.548.705.750'], ['D12.776.124.486.4... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rapid presumptive diagnosis of hantavirus cardiopulmonary syndrome by peripheral blood smear review. | Hantavirus cardiopulmonary syndrome (HCPS) is a rare but frequently lethal acute zoonotic viral infection in rural North America. The rapidity of progression from febrile prodrome to cardiogenic shock and noncardiogenic pulmonary edema requiring intensive care creates high diagnostic urgency and a need for a rapid scre... | ['Adult', 'Blood Specimen Collection', 'Blood Volume', 'Cohort Studies', 'Hantavirus', 'Hantavirus Pulmonary Syndrome', 'Hematologic Tests', 'Humans', 'Middle Aged', 'Myeloproliferative Disorders', 'Neutrophils', 'Polycythemia', 'Pulmonary Edema', 'Radiography, Thoracic', 'Retrospective Studies', 'Sensitivity and Speci... | 11,710,682 | [['M01.060.116'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['G09.188.130', 'G09.330.380.092'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B04.820.480.750.440'], ['C01.925.782.147.420.380', 'C08.618.846.450'], ['E01.370.225.625', 'E05.200.625'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Silver Metallic Cyclodextrin-Core Star mPEG. | A novel silver metallic â-cyclodextrin (â-CD)-core star methoxypolyethylene glycol (mPEG) (SM-CD-SPEG) is presented. For this, a well-defined water-soluble â-CD-core star mPEG with aldehyde groups (CD-star(ald)PEG, III) is first designed and synthesized via the copper-catalyzed azide-alkyne click reaction. Then, silver... | ['Cyclodextrins', 'Metal Nanoparticles', 'Micelles', 'Polyethylene Glycols', 'Polymers', 'Silver'] | 30,561,864 | [['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['J01.637.512.600.500'], ['D05.374', 'D26.255.560'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Immunohistochemical localization of prostaglandin H synthase in the sheep placenta from early pregnancy to term. | Prostaglandin H synthase (PGHS) activity within intrauterine tissues is considered to catalyze a critical step in prostaglandin (PG) biosynthesis at parturition. In sheep, the placenta is a major site of PG production throughout pregnancy, but little information is available concerning the cells that are responsible. T... | ['Animals', 'Female', 'Gestational Age', 'Placenta', 'Pregnancy', 'Pregnancy Proteins', 'Pregnancy, Animal', 'Prostaglandin-Endoperoxide Synthases', 'Sheep', 'Trophoblasts'] | 1,786,297 | [['B01.050'], ['G07.345.500.325.235.968', 'G08.686.320'], ['A16.710'], ['G08.686.784.769'], ['D12.776.780'], ['G08.686.784.769.498'], ['D08.811.600.720', 'D08.811.682.690.708.715'], ['B01.050.150.900.649.313.500.380.791'], ['A11.382.992', 'A16.254.500.766', 'A16.710.802']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
User-Centered Design, Experience, and Usability of an Electronic Consent User Interface to Facilitate Informed Decision-Making in an HIV Clinic. | Health information exchange is the electronic accessibility and transferability of patient medical records across various healthcare settings and providers. In some states, patients have to formally give consent to allow their medical records to be electronically shared. The purpose of this study was to apply a novel u... | ['Ambulatory Care', 'Cross-Sectional Studies', 'Decision Making', 'Electronic Health Records', 'HIV Infections', 'Health Information Exchange', 'Humans', 'Informed Consent', 'Patients', 'Qualitative Research', 'Surveys and Questionnaires', 'User-Computer Interface'] | 28,481,754 | [['E02.760.106', 'N02.421.585.106'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Impact of visit copayments on outpatient mental health utilization by members of a health maintenance organization. | OBJECTIVE: The authors examined the impact of increasing cost sharing on use of outpatient mental health services.METHOD: A quasi-experimental design was used to study outpatient utilization by members of a health maintenance organization (HMO) who were subject to increasing copayments for mental health visits (state g... | ['Ambulatory Care', 'Appointments and Schedules', 'Attitude to Health', 'Community Mental Health Services', 'Cost Sharing', 'Deductibles and Coinsurance', 'Fees and Charges', 'Health Benefit Plans, Employee', 'Health Care Reform', 'Health Maintenance Organizations', 'Humans', 'Insurance Claim Review', 'Probability', 'U... | 8,610,819 | [['E02.760.106', 'N02.421.585.106'], ['N04.452.095'], ['F01.100.150', 'N05.300.150'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['N03.219.151.170', 'N03.219.521.576.090'], ['N03.219.151.170.300', 'N03.219.521.576.090.300'], ['N03.219.442'], ['N01.824.417.700.325', 'N03.219.521.576.343.290', 'N04.452.677.80... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Salvage treatment for local or local-regional recurrence after initial breast conservation treatment with radiation for ductal carcinoma in situ. | The present study evaluated the outcome of salvage treatment for women with local or local-regional recurrence after initial breast conservation treatment with radiation for mammographically detected ductal carcinoma in situ (DCIS; intraductal carcinoma) of the breast. The study cohort consisted of 90 women with local ... | ['Adult', 'Breast Neoplasms', 'Carcinoma, Intraductal, Noninfiltrating', 'Cohort Studies', 'Female', 'Humans', 'Mammography', 'Mastectomy, Segmental', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prognosis', 'Salvage Therapy'] | 16,043,350 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E04.466.701'], ['M01.060.116... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Feasibility Randomized Controlled Crossover Trial of Home-Based Warm Footbath to Improve Sleep in the Chronic Phase of Traumatic Brain Injury. | INTRODUCTION: Sleep disturbance is a common complaint after traumatic brain injury (TBI). The aim of this study was to examine the effects of a home-based warm footbath intervention on sleep in patients with TBI.METHODS: This was a randomized controlled crossover study, and 23 adults with TBI were recruited and randomi... | ['Actigraphy', 'Adult', 'Baths', 'Brain Injuries', 'Complementary Therapies', 'Cross-Over Studies', 'Female', 'Foot', 'Hot Temperature', 'Humans', 'Male', 'Sleep Initiation and Maintenance Disorders'] | 29,117,034 | [['E01.370.520.049', 'E05.003.500'], ['M01.060.116'], ['E02.056.110'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E02.190'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['A01.378.610.250'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.30... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The recombinant fusion protein of cholera toxin B and neutrophil-activating protein expressed on Bacillus subtilis spore surface suppresses allergic inflammation in mice. | The neutrophil-activating protein of Helicobacter pylori (HP-NAP) has been identified as a modulator with anti-Th2 inflammation activity, and cholera toxin B (CTB) is a mucosal adjuvant that can also induce antigen tolerance. In this study, we constructed a CTB-NAP fusion protein on the surface of Bacillus subtilis spo... | ['Adjuvants, Immunologic', 'Administration, Oral', 'Animals', 'Asthma', 'Bacillus subtilis', 'Bacterial Proteins', 'Cholera Toxin', 'Hypersensitivity', 'Immunoglobulin E', 'Inflammation', 'Interferon-gamma', 'Interleukin-10', 'Lung', 'Mice', 'Mice, Inbred BALB C', 'Ovalbumin', 'Recombinant Fusion Proteins', 'Spores, Ba... | 28,608,279 | [['D27.505.696.477.067'], ['E02.319.267.100'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['D08.811.913.400.72... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: a randomized controlled trial. | BACKGROUND: Paralytic ileus that develops after elective surgery is a common and uncomfortable complication and is considered inevitable after an intraperitoneal operation.OBJECTIVE: The purpose of this study was to investigate whether coffee consumption accelerates the recovery of bowel function after complete staging... | ['Adult', 'Aged', 'Aorta', 'Coffee', 'Defecation', 'Female', 'Flatulence', 'Gastrointestinal Motility', 'Genital Neoplasms, Female', 'Gynecologic Surgical Procedures', 'Humans', 'Hysterectomy', 'Ileus', 'Intestinal Pseudo-Obstruction', 'Lymph Node Excision', 'Middle Aged', 'Ovariectomy', 'Pelvis', 'Postoperative Care',... | 27,780,709 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.056'], ['D20.215.784.249', 'G07.203.100.325', 'J02.200.325'], ['G10.261.165'], ['C23.888.821.360'], ['G10.261.360'], ['C04.588.945.418', 'C13.351.937.418'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['C06.405.469.531.492']... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Technology transfer of brain-computer interfaces as assistive technology: barriers and opportunities. | This paper provides an analysis of perspectives from different stakeholders on the state-of-the-art of BCI. Three barriers for technology transfer of BCIs as access technologies are identified. First, BCIs are developed with a narrow focus on creating a reliable technology, while a broader focus on creating a usable te... | ['Brain-Computer Interfaces', 'Equipment Design', 'Humans', 'Neurological Rehabilitation', 'Self-Help Devices', 'Technology Transfer'] | 25,595,535 | [['E07.305.076'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.477', 'E02.831.477', 'H02.403.680.600.750', 'N02.421.784.511'], ['E07.796'], ['J01.897.900', 'L01.143.320.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Risk factors for hepatocellular carcinoma in northern Italy. | The role of socio-demographic factors, lifestyle habits and selected dietary factors on the risk of hepatocellular carcinoma was evaluated in a hospital-based case-control study conducted in Northern Italy on 151 patients with hepatocellular carcinoma and 1,051 controls in hospital for acute, non-neoplastic or digestiv... | ['Carcinoma, Hepatocellular', 'Diet', 'Hepatitis B', 'Humans', 'Italy', 'Liver Neoplasms', 'Retinoids', 'Risk Factors', 'Smoking'] | 2,847,988 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G07.203.650.240'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['D02... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Evidence that increased 5-HT release evokes region-specific effects on blood-oxygenation level-dependent functional magnetic resonance imaging responses in the rat brain. | This study aimed to determine the potential of in vivo functional magnetic resonance imaging (fMRI) methods as a non-invasive means of detecting effects of increased 5-HT release in brain. Changes in blood-oxygenation level-dependent (BOLD) contrast induced by administration of the 5-HT-releasing agent, fenfluramine, w... | ['Animals', 'Brain', 'Brain Mapping', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Excitatory Amino Acid Transporter 3', 'Fenclonine', 'Fenfluramine', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Oncogene Proteins v-fos', 'Oxygen', 'Rats', 'Rats, Sprague-Dawley', 'Serotonin... | 19,174,180 | [['B01.050'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['D12.776.157.530.200.249.500.500.875', 'D12.776.157.530.450.625.147.875', 'D12.776.157.530.562.374.781.781', 'D12.776.157.530.937.250.500.875', 'D12.776... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Inhibiting fly ash reactivity by adding N- and S- containing compounds. | The inhibitory effect of thiourea (TUA), ammonium thiosulfate (TSA) and amidosulfonic acid (ASA) on the reactivity of fly ash air was investigated using a thermobalance at different heating rates (5, 10 and 20 K min-1). A model fly ash (activated carbon + 50 wt% CuCl2·2H2O, pyrolyzed at 700 °C and washed) was used as c... | ['Coal Ash', 'Incineration', 'Particulate Matter', 'Sulfonic Acids', 'Thiosulfates', 'Thiourea'] | 30,077,109 | [['D20.633.110'], ['N06.850.860.510.900.600.500'], ['D20.633'], ['D01.029.260.877.740', 'D01.875.800.740', 'D02.886.645.600'], ['D01.248.497.158.845.703', 'D01.875.800.800.850.900'], ['D02.065.950.898', 'D02.886.904']] | ['Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Multifunctional Compound AD-35 Improves Cognitive Impairment and Attenuates the Production of TNF-á and IL-1â in an Aâ25-35-induced Rat Model of Alzheimer's Disease. | The dyshomeostasis of transition metal ions, accumulation of amyloid-â (Aâ) senile plaques and neuroinflammatory response found in the brain of patients with Alzheimer's disease (AD) have been suggested to be involved in AD pathogenesis. Novel compounds capable of targeting metal-Aâ species and neuroinflammation would ... | ['Alzheimer Disease', 'Amyloid beta-Peptides', 'Animals', 'Astrocytes', 'Brain', 'Cell Line, Tumor', 'Cholinesterase Inhibitors', 'Cognitive Dysfunction', 'Disease Models, Animal', 'Donepezil', 'Humans', 'Indans', 'Interleukin-1beta', 'Male', 'Memory Disorders', 'Nootropic Agents', 'Peptide Fragments', 'Piperidines', '... | 28,157,092 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['A11.251.210.190', 'A11.251.860.180'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['F03.61... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Factors affecting the efficiency of CD8+ T cell cross-priming with exogenous antigens. | Processing of exogenous protein Ags by APC leads predominantly to presentation of peptides on class II MHC and, thus, stimulation of CD4+ T cell responses. However, "cross-priming" can also occur, whereby peptides derived from exogenous Ags become displayed on class I MHC molecules and stimulate CD8+ T cell responses. ... | ['Antibodies, Viral', 'Antigen-Presenting Cells', 'Antigens, Viral', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cell Count', 'Cells, Cultured', 'Cytokines', 'Cytomegalovirus', 'Dendritic Cells', 'Dose-Response Relationship, Immunologic', 'Epitopes, T-Lymphocyte', 'Histocompatibility Antigens Class I',... | 11,390,476 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.066', 'A15.382.066'], ['D23.050.327'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The phosphodiesterase 4 inhibitor apremilast inhibits Th1 but promotes Th17 responses induced by 6-sulfo LacNAc (slan) dendritic cells. | BACKGROUND: The phosphodiesterase 4 (PDE4) inhibitor apremilast increases cellular cAMP levels and has proven effective in the treatment of psoriasis and psoriasis arthritis. We recently described 6-sulfo LacNAc dendritic cells (slanDCs) as immature DCs in blood and as a subset of inflammatory dermal DCs in psoriasis w... | ['Amino Sugars', 'Coculture Techniques', 'Cyclic AMP', 'Cytokines', 'Dendritic Cells', 'Humans', 'Immunologic Factors', 'Leukocytes, Mononuclear', 'Nuclear Receptor Subfamily 1, Group F, Member 3', 'Phosphodiesterase 4 Inhibitors', 'Psoriasis', 'T-Box Domain Proteins', 'Th1 Cells', 'Th17 Cells', 'Thalidomide', 'Tumor N... | 28,499,587 | [['D09.067'], ['E05.481.500.374'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigation of the imaging properties of an x-ray film scanner. | In this note, the imaging properties of a CCD x-ray film scanner were investigated. The relationship between optical density and the logarithm of output pixel value provides information on the linearity of the system. The resolution properties of the scanner can be characterized by the presampling modulation transfer f... | ['Equipment Failure Analysis', 'Fingers', 'Humans', 'Phantoms, Imaging', 'Radiographic Image Enhancement', 'Radiographic Image Interpretation, Computer-Assisted', 'Reproducibility of Results', 'Sensitivity and Specificity', 'X-Ray Film', 'X-Ray Intensifying Screens'] | 15,552,094 | [['E05.325.192'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600'], ['E01.158.600.680', 'E01.370.350.350.700', 'E01.370.350.700.705', 'L01.313.500.750.100.158.600.680'], ['E05.318.370.725', 'E05.337.851', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Evidence of iteroparity in the widely distributed diadromous fish inanga Galaxias maculatus and potential implications for reproductive output. | Gaps in understanding variability among populations of inanga Galaxias maculatus in the timing of reproduction were addressed in southern New Zealand (NZ), where G. maculatus constitutes a declining fishery. Reproductive activity was delayed by 1 month on the west coast compared with the east coast and the west coast s... | ['Animals', 'Ecosystem', 'Fertility', 'New Zealand', 'Osmeriformes', 'Reproduction', 'Seasons'] | 27,470,074 | [['B01.050'], ['G16.500.275.157', 'N06.230.124'], ['G08.686.210'], ['Z01.639.760.747', 'Z01.678.100.747'], ['B01.050.150.900.493.595'], ['G08.686.784'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Synovial membrane and fluid morphologic alterations in early rheumatoid arthritis: microvascular injury and virus-like particles. | Eight patients have been studied during the first 6 weeks of rheumatoid synovitis. All of them exhibited microvascular injury, which was manifested by gaps between endothelial cells, vascular occlusion, erythrocyte extravasation, or endothelial cell injury. In four patients, a variety of virus-like particles were found... | ['Adult', 'Arthritis, Rheumatoid', 'Basement Membrane', 'Biopsy, Needle', 'Capillaries', 'Endothelium', 'Female', 'Humans', 'Lymphocytes', 'Male', 'Middle Aged', 'Neutrophils', 'Phagocytosis', 'Plasma Cells', 'RNA Viruses', 'Synovial Fluid', 'Synovial Membrane'] | 1,057,866 | [['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A10.272.220', 'A10.615.179'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['A07.015.461.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modulation of uterine sensitivity to decidual induction in the rat by nicotinamide; challenge and extension of a model of progestational differentiation. | A recently constructed model describes pyridine nucleotide metabolism as a key target of progesterone action during early progestational differentiation of the uterus ( progestation ). The present study was designed to challenge this model. Using uterine sensitivity to decidual induction as a "whole animal" index of pr... | ['Animals', 'Decidua', 'Embryo Implantation', 'Female', 'NAD', 'NADP', 'Niacinamide', 'Pregnancy', 'Progesterone', 'Rats'] | 6,232,957 | [['B01.050'], ['A05.360.319.679.490.373', 'A16.710.289'], ['G08.686.784.170.104.500'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749'], ['D03.066.515.530', 'D03.383.725.547.530'], [... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence and risk factors of diabetic retinopathy in non-Hispanic whites and Hispanics with NIDDM. San Luis Valley Diabetes Study. | Diabetic retinopathy (DR) is the leading cause of blindness in adults in the United States. Because photocoagulation can reduce the incidence of blindness from severe DR by approximately 50%, it is important to identify people at increased risk for DR so that appropriate treatment can be accomplished. Use of population... | ['Adult', 'Aged', 'Biomarkers', 'Blood Pressure', 'Colorado', 'Diabetes Mellitus, Type 2', 'Diabetic Retinopathy', 'European Continental Ancestry Group', 'Glycated Hemoglobin A', 'Hispanic Americans', 'Humans', 'Middle Aged', 'Prevalence', 'Reference Values', 'Risk Factors'] | 2,792,575 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['Z01.107.567.875.760.210'], ['C18.452.394.750.149', 'C19.246.300'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['M01.686.508.400'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Micropattern orientation and spatial localization. | A current, popular, theory of spatial localization holds that the visual system represents the location of simple objects by a single positional tag, the accuracy of which is largely independent of the internal properties of the object. We have already presented evidence of the limitations of such a view (Keeble & Hess... | ['Anisotropy', 'Discrimination, Psychological', 'Humans', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Psychophysics', 'Rotation', 'Sensory Thresholds', 'Space Perception'] | 11,712,985 | [['G01.590.040', 'G02.050'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['E01.370.685', 'F04.096.753'], ['G01.482.703'], ['F02.463.593.710'], ['F02.463.593.778']] | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Is it still ethical to conduct clinical trials against a placebo? A review of the ethical and methodological controversy]. | UNLABELLED: A DEVELOPING CONTROVERSY: The marketing authorization for new drugs from the regulatory authorities'and ethical point of view, is only possible following convincing proof of their efficacy and safety. Between the drug registration authorities, who underline the necessity of early assessment against a placeb... | ['Clinical Trials as Topic', 'Ethics, Clinical', 'Humans', 'Marketing', 'Placebos'] | 12,876,524 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['K01.752.566.479.045.500', 'K01.752.566.479.171.132', 'N05.350.200.500', 'N05.350.340.162'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.219.687'], ['D26.660', 'E02.785']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The paradox of HIV/AIDS as expanding consciousness. | A heuristic approach employing Newman's method for pattern identification was used to examine the theory of health as expanding consciousness in persons with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). Themes derived from the interview of nine gay men portrayed a pattern of alienation ... | ['Acquired Immunodeficiency Syndrome', 'Adaptation, Psychological', 'Adult', 'Attitude to Health', 'Consciousness', 'Cultural Evolution', 'Family', 'HIV Infections', 'Health Behavior', 'Homosexuality', 'Human Development', 'Humans', 'Loneliness', 'Male', 'Middle Aged', 'Models, Nursing', 'Nursing Methodology Research',... | 8,203,827 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['F01.058'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['F02.463.188.409', 'F02.830.233'], ['I01.076.201.450.370'], ['F01.829.263', 'I01.880.853.... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Study of the anatomical variations of vertebral artery in C2 vertebra with magnetic resonance imaging and its application in the C1-C2 transarticular screw fixation. | STUDY DESIGN: Use of magnetic resonance imaging (MRI) with Constructive Interference in Steady State (CISS) sequence and isometric voxels to demonstrate the anatomic variations of vertebral artery in C2 vertebra.OBJECTIVES: To determine the transarticular screw trajectory on CISS MRI and to identify patients with anato... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Atlanto-Axial Joint', 'Axis, Cervical Vertebra', 'Bone Screws', 'Cervical Atlas', 'Child', 'Female', 'Fracture Fixation', 'Humans', 'Image Processing, Computer-Assisted', 'Internal Fixators', 'Joint Instability', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', ... | 20,118,834 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.835.583.097'], ['A02.835.232.834.151.383'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['A02.835.232.834.151.500'], ['M01.060.406'], ['E04.555.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Role of remission clinics in the longitudinal treatment of CKD. | Heavy proteinuria is a major determinant of progression to ESRD for patients with chronic nephropathies and reducing proteinuria should be a key target for renoprotective therapy. In the Remission Clinic, we applied a multimodal intervention to target urinary proteins in 56 consecutive patients who had >3 g proteinuria... | ['Algorithms', 'Chronic Disease', 'Cohort Studies', 'Disease Progression', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kidney Diseases', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Proteinuria'] | 18,354,029 | [['G17.035', 'L01.224.050'], ['C23.550.291.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.291.656'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['C12.777.419.780.750.500', 'C13.351.968.419.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Limb deformity in a newborn. Is rifampicin just an innocent bystander? | OBJECTIVE: The first-line antituberculous agents for use during pregnancy have minimal teratogenic effects. The possibility of limb deformity during rifampin use, however, was reported by some researchers.CASE REPORT: A male newborn was born with a hypoplastic right forearm to a mother with tuberculosis who used isonia... | ['Antitubercular Agents', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Rifampin', 'Tuberculosis', 'Upper Extremity Deformities, Congenital', 'Young Adult'] | 25,720,727 | [['D27.505.954.122.085.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['D03.633.400.811.700', 'D04.345.295.750.700'], ['C01.150.252.410.040.552.846'], ['C05.660.585.988', 'C16.131.621.585.988'], ['M01.060.116.815']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A simple identification scheme for coagulase negative staphylococci from bovine mastitis. | Coagulase-negative staphylococci from cases of bovine mastitis were identified to species level by using an identification scheme based on a three-plate test system which tested for DNase on DNA agar, for protease on calcium caseinate agar, and for the organism's sensitivity to novobiocin, desferrioxaminine (deferoxami... | ['Agar', 'Animals', 'Cattle', 'Coagulase', 'Deoxyribonucleases', 'Endopeptidases', 'Female', 'Fosfomycin', 'Mastitis, Bovine', 'Sensitivity and Specificity', 'Staphylococcus', 'Staphylococcus epidermidis'] | 7,817,013 | [['D09.698.360.041'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.277.656.300.174', 'D12.776.097.181'], ['D08.811.277.352.335'], ['D08.811.277.656.300'], ['D02.705.429.625'], ['C22.196.581'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A novel role for RAD54: this host protein modulates geminiviral DNA replication. | Geminiviruses primarily encode only few factors, such as replication initiator protein (Rep), and need various host cellular machineries for rolling-circle replication (RCR) and/or recombination-dependent replication (RDR). We have identified a host factor, RAD54, in a screen for Rep-interacting partners and observed i... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'Base Sequence', 'Begomovirus', 'DNA Helicases', 'DNA Repair Enzymes', 'DNA Replication', 'DNA, Viral', 'Host-Pathogen Interactions', 'Microscopy, Electron', 'Molecular Sequence Data', 'Peptide Library', 'Protein Binding', 'Protein Interaction Domains and M... | 22,171,001 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B04.280.350.100', 'B04.715.270.100'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D08.811.074'], ['G02.111.225', 'G05.226'], ['D13.444.308.568'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A Fetal ECG Monitoring System Based on the Android Smartphone. | In this paper, a fetal electrocardiogram (ECG) monitoring system based on the Android smartphone was proposed. We designed a portable low-power fetal ECG collector, which collected maternal abdominal ECG signals in real time. The ECG data were sent to a smartphone client via Bluetooth. Smartphone app software was devel... | ['Algorithms', 'Electrocardiography', 'Female', 'Fetal Monitoring', 'Humans', 'Pregnancy', 'Signal Processing, Computer-Assisted', 'Smartphone', 'Software', 'Wearable Electronic Devices', 'Wireless Technology'] | 30,678,252 | [['G17.035', 'L01.224.050'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.378.230', 'E01.370.520.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['L01.224.800'], ['L01.178.847.698.300.250', 'L01.224.230.260.550.500.750'], ['L01.224.900'], ['E07.305.906'], ['L01.178.847.950']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Generalization of microdosimetric correlations for the non-Poisson random process]. | The relationship between a radiation dose and moments of density of sensitive microvolumes distribution by the value of the absorbed specific energy was found for a random non-Poisson's distribution of the number of particle passages through a cell microvolume. A deviation from the Poisson's distribution was shown to c... | ['Cells', 'Mathematics', 'Models, Biological', 'Radiation Dosage'] | 3,423,239 | [['A11'], ['H01.548'], ['E05.599.395'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250']] | ['Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Differential impact of inflammation on six laboratory assays measuring residual arachidonic acid-inducible platelet reactivity during dual antiplatelet therapy. | AIMS: Inflammation has been postulated to modify the platelet response to aspirin treatment, thereby causing high on-treatment residual platelet reactivity (HRPR). Both high levels of inflammatory markers and HRPR have been linked to adverse cardiovascular events. We aimed to study the impact of inflammation on residua... | ['Aged', 'Arachidonic Acids', 'Aspirin', 'Blood Platelets', 'C-Reactive Protein', 'Electrochemistry', 'Female', 'Humans', 'Immunoassay', 'Inflammation', 'Interleukin-6', 'Male', 'Middle Aged', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Predictive Value of Tests', 'Risk Factors', 'Thromboxane B2'] | 23,739,624 | [['M01.060.116.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['D02.455.426.559.389.657.410.595.176'], ['A11.118.188', 'A15.145.229.188'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['H01.181.529.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['C2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Embolisation of renal arteriovenous malformation (AVM) in pregnancy. | A case of congenital renal arteriovenous malformation (AVM), presenting with profuse haematuria in the second trimester of pregnancy is reported. Selective embolisation with polyvinyl alcohol particles and absolute alcohol successfully ablated the lesion and a healthy infant was delivered at term five months later. Ren... | ['Adult', 'Arteriovenous Malformations', 'Balloon Occlusion', 'Female', 'Humans', 'Kidney Diseases', 'Pregnancy', 'Pregnancy Complications'] | 11,394,340 | [['M01.060.116'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['E02.148.106', 'E02.520.392.500', 'E02.926.500.074', 'E05.157.063'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['G08.686.784.769'], ['C13.703']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cryptic species of Archinome (Annelida: Amphinomida) from vents and seeps. | Since its description from the Galapagos Rift in the mid-1980s, Archinome rosacea has been recorded at hydrothermal vents in the Pacific, Atlantic and Indian Oceans. Only recently was a second species described from the Pacific Antarctic Ridge. We inferred the identities and evolutionary relationships of Archinome repr... | ['Animals', 'DNA, Intergenic', 'DNA, Mitochondrial', 'Ecosystem', 'Electron Transport Complex IV', 'Hydrothermal Vents', 'Molecular Sequence Data', 'Phylogeny', 'Polychaeta', 'RNA, Ribosomal', 'Sequence Analysis, DNA'] | 24,026,823 | [['B01.050'], ['D13.444.308.324', 'G05.360.340.024.220'], ['D13.444.308.283.225'], ['G16.500.275.157', 'N06.230.124'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['G01.311.355.750.500.400', 'G16.500.275.260.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Hepatitis B virus candidate subgenotype I1 varies in distribution throughout Guangxi, China and may have originated in Long An county, Guangxi. | Sequencing of the complete hepatitis B virus (HBV) genomes from Vietnam, China and Laos led to the identification of a complex recombinant, referred to initially as an aberrant genotype and later proposed to be a new genotype, I. However, epidemiological data regarding this new genotype are lacking. A cross-sectional s... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Child', 'Child, Preschool', 'China', 'Cluster Analysis', 'Cohort Studies', 'Cross-Sectional Studies', 'DNA, Viral', 'Ethnic Groups', 'Female', 'Genome, Viral', 'Genotype', 'Hepatitis B', 'Hepatitis B virus', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Molecular Epidemiolo... | 23,508,905 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.8... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
[Management of T1a vocal fold carcinoma]. | About 2/3 of the larynx carcinomas affect the vocal chords. The main risk factor is smoking. Carcinomas in this localisation often arise from leukoplakias with dysplasia. A typical symptom is dysphonia. Arrest of vibration in microlaryngostroboscopy is a hint that a carcinoma could be present. Transoral laser cordectom... | ['Biopsy', 'Carcinoma, Squamous Cell', 'Cell Transformation, Neoplastic', 'Female', 'Humans', 'Laryngeal Neoplasms', 'Laryngectomy', 'Laryngoscopy', 'Laser Therapy', 'Male', 'Neoplasm Metastasis', 'Neoplasm Staging', 'Prognosis', 'Survival Rate', 'Vocal Cords'] | 23,929,210 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.697.098.500', 'C23.550.727.098.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.36... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Variations in serum sphingolipid levels associate with liver fibrosis progression and poor treatment outcome in hepatitis C virus but not hepatitis B virus infection. | UNLABELLED: Ablation of very-long-chain ceramides (Cers) with consecutive elevations in sphinganine levels has been shown to cause a severe hepatopathy in a knockout mouse model. We have recently shown that serum sphingolipids (SLs) are deregulated in patients with chronic liver disease. However, their role as possible... | ['Adolescent', 'Adult', 'Aged', 'Disease Progression', 'Female', 'Hepatitis B, Chronic', 'Hepatitis C, Chronic', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Retrospective Studies', 'Sphingolipids', 'Sphingosine'] | 25,348,752 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.656'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Self-efficacy partially mediates the effect of a school-based physical-activity intervention among adolescent girls. | BACKGROUND: This study evaluated the effects of the Lifestyle Education for Activity Program (LEAP), a comprehensive school-based intervention emphasizing changes in instruction and school environment, on variables derived from social-cognitive theory (SCT) as mediators of change in physical activity among black and wh... | ['Adolescent', 'Adolescent Behavior', 'Exercise', 'Female', 'Humans', 'Self Efficacy', 'South Carolina'] | 15,066,366 | [['M01.060.057'], ['F01.145.022'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.792.700'], ['Z01.107.567.875.075.662', 'Z01.107.567.875.750.700']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
The influence of upper limb position on the effect of a contrast agent in chest CT enhancement. | PURPOSE: To compare the influence of two different upper limb positions on contrast agent effects in chest CT enhancement.MATERIALS AND METHODS: In 142 patients undergoing contrast-enhanced CT chest scanning, an indwelling venous catheter was placed in the right hand and iodinated contrast agent was injected through a ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Arm', 'Artifacts', 'Contrast Media', 'Female', 'Humans', 'Iohexol', 'Male', 'Middle Aged', 'Patient Positioning', 'Radiographic Image Enhancement', 'Radiographic Image Interpretation, Computer-Assisted', 'Radiography, Thoracic', 'Reproducibility of Res... | 23,357,251 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['A01.378.800.075'], ['E05.047'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.400.880.400', 'D02.455.426.559.389.127.375.880.400'], ['M01.060.116.630'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effects of in vitro exposure to autologous blood and serum on expression of interleukin-8, interleukin-1â, and chemokine (C-X-C motif) ligand 2 in equine primary bronchial epithelial cell cultures. | OBJECTIVE: To examine the effects of in vitro exposure to solutions of autologous horse blood (AHB) and autologous horse serum (AHS) on expressions of selected cytokine genes in equine primary bronchial epithelial cell (BEC) cultures and to contrast these responses to those induced in BEC cultures by endotoxin and hay ... | ['Animals', 'Bronchi', 'Cells, Cultured', 'Chemokine CXCL2', 'Epithelial Cells', 'Gene Expression Regulation', 'Horses', 'Interleukin-1beta', 'Interleukin-8', 'Primary Cell Culture', 'Respiratory Mucosa', 'Serum'] | 22,280,393 | [['B01.050'], ['A04.411.125'], ['A11.251'], ['D12.644.276.374.200.120.100', 'D12.644.276.374.200.600.940', 'D12.776.467.374.200.120.100', 'D12.776.467.374.200.600.940', 'D23.125.300.120.100', 'D23.125.300.600.940', 'D23.469.200.120.100', 'D23.469.200.600.940', 'D23.529.374.200.120.100', 'D23.529.374.200.600.940'], ['A1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Targeting low-normal or high-normal mean arterial pressure after cardiac arrest and resuscitation: a randomised pilot trial. | PURPOSE: We aimed to determine the feasibility of targeting low-normal or high-normal mean arterial pressure (MAP) after out-of-hospital cardiac arrest (OHCA) and its effect on markers of neurological injury.METHODS: In the Carbon dioxide, Oxygen and Mean arterial pressure After Cardiac Arrest and REsuscitation (COMACA... | ['Aged', 'Arterial Pressure', 'Cardiopulmonary Resuscitation', 'Critical Care', 'Feasibility Studies', 'Female', 'Humans', 'Hypertension', 'Hypotension', 'Hypoxia-Ischemia, Brain', 'Male', 'Middle Aged', 'Out-of-Hospital Cardiac Arrest', 'Phosphopyruvate Hydratase', 'Pilot Projects', 'Time Factors'] | 30,443,729 | [['M01.060.116.100'], ['G09.330.380.076.347'], ['E02.365.647.110'], ['E02.760.190', 'N02.421.585.190'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.907.514'], ['C10.228.140.300.150.716', 'C10.228.140.624.500', ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stimulating effect of ileal pancreaticobiliary secretion on ileal apolipoprotein A-IV mRNA expression in fasted rats. | The effect of pancreaticobiliary secretion on the intestinal expression of the apo A-IV gene was examined in fasted rats. Pancreaticobiliary diversion, but not biliary diversion alone, into the ileum increased the ileal apo A-IV mRNA expression by 24 h post-operation. Jejunal apo A-IV mRNA was reduced by biliary exclus... | ['Animals', 'Apolipoproteins A', 'Biliary Tract', 'Biliopancreatic Diversion', 'Fasting', 'Ileum', 'Male', 'Pancreas', 'RNA, Messenger', 'Rats', 'Rats, Wistar', 'Stimulation, Chemical', 'Up-Regulation'] | 9,178,567 | [['B01.050'], ['D10.532.091.200', 'D12.776.070.400.200', 'D12.776.521.120.200'], ['A03.159'], ['E04.210.120.086', 'E04.210.169'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['A03.734'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects. | Previous studies have shown an abnormality of the spermidine-to-spermine (Spd/Spm) ratio in whole blood of cystic fibrosis homo-and heterozygotes. To investigate Spd and Spm distribution amoung blood components as a possible cause of the abnormality, blood was fractionated using Rabinowitz's glass bead technique and Bo... | ['Cell Fractionation', 'Cell Separation', 'Citrates', 'Cystic Fibrosis', 'Heparin', 'Humans', 'Male', 'Polyamines', 'Spermidine', 'Spermine'] | 953,366 | [['E05.242.251'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['D02.241.081.901.434'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.782'], ['D02.092.211.415.701.801', 'D02.092.782.677'], ['D02.092.211.415.701... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: a multicenter phase II study by the Cancer Therapeutic Research Group. | The main objectives of this study were to assess the use of irinotecan, 5-fluorouracil (5-FU), and leucovorin (FA) as neoadjuvant chemotherapy for patients with unresectable colorectal liver metastases and to determine the response rate and proportion of patients that could be down-staged to resectable tumors. Forty pa... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Camptothecin', 'Colorectal Neoplasms', 'Combined Modality Therapy', 'Disease Progression', 'Female', 'Fluorouracil', 'Humans', 'Infusions, Intravenous', 'Irinotecan', 'Leucovorin', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoadjuva... | 16,110,141 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.132.151'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E02.186'], ['C23.550.291.656'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The impact of metabolic syndrome on carotid intima media thickness. | OBJECTIVES: Metabolic syndrome (MetS) is a cluster of metabolic abnormalities involving several cardiovascular risk factors. Carotid intima media thickness (CIMT) is an important early screening tool to assess subclinical manifestation of cardiovascular and metabolic diseases. We aimed to investigate the impact of MetS... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Carotid Arteries', 'Carotid Intima-Media Thickness', 'Case-Control Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Insulin Resistance', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Obesity', 'Obesity, Morbid', 'Overweight', 'Prospective Studi... | 24,065,221 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A07.015.114.186'], ['E01.370.350.850.150', 'E01.370.370.180', 'G09.330.210'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A new graphical format to communicate treatment effects to patients-A web-based randomized controlled trial. | OBJECTIVE: Patients making treatment decisions require understandable evidence-based information. However, evidence on graphical presentation of benefits and side-effects of medical treatments is not conclusive. The study evaluated a new space-saving format, CLARIFIG (clarifying risk figures), aiming to facilitate accu... | ['Adult', 'Communication', 'Computer Graphics', 'Decision Making', 'Decision Support Techniques', 'Female', 'Humans', 'Internet', 'Male', 'Patient Education as Topic', 'Patient Preference', 'Risk Assessment'] | 27,981,688 | [['M01.060.116'], ['F01.145.209', 'L01.143'], ['L01.224.108', 'L01.296.110'], ['F02.463.785.373'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['I02.233.332.500', 'N02.421.726.407.680'], ['F01.100.150.750.625.500', 'F01.145.488.887.625.500', 'N04.452.822... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice. | DNA vaccines are cost-effective to manufacture on a global scale and Tat-based DNA vaccines have yielded protective outcomes in preclinical and clinical models of human immunodeficiency virus (HIV), highlighting the potential of such vaccines. However, Tat-based DNA vaccines have been poorly immunogenic, and despite th... | ['Animals', 'Apoptosis Regulatory Proteins', 'Chimera', 'HIV Antibodies', 'HIV Infections', 'HIV-1', 'Humans', 'Immunity, Cellular', 'Mice', 'Recombinant Fusion Proteins', 'Survivin', 'Vaccines, DNA', 'tat Gene Products, Human Immunodeficiency Virus'] | 27,358,023 | [['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['B05.200'], ['D12.776.124.486.485.114.254.150.440', 'D12.776.124.790.651.114.254.150.440', 'D12.776.377.715.548.114.254.150.440'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the application values of different combination schemes of liquid-based cytology and high-risk human papilloma virus test in the screening of high-grade cervical lesions. | The aim of this study was to explore the value of different combination schemes of liquid-based cytology (LBC) and high-risk human papilloma virus (HPV) test in the screening of high-grade (?CIN 2) cervical lesions. From 5727 women who had undergone examinations with LBC and high-risk HPV test, 1884 patients with posit... | ['Adolescent', 'Adult', 'Aged', 'Cervical Intraepithelial Neoplasia', 'Diagnostic Screening Programs', 'Female', 'Humans', 'Liquid Biopsy', 'Middle Aged', 'Papillomavirus Infections', 'Precancerous Conditions', 'Predictive Value of Tests', 'Sensitivity and Specificity', 'Young Adult'] | 30,484,489 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.240.250'], ['N02.421.726.233.138'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.384.100.396', 'E01.370.225.998.054.396', 'E05.200.500.384.100.396', 'E05.200.998.054.396', 'E05.242.384.100.396'], ['M01.060.116.630'], ['C01.9... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Properties and subcellular localization of myocardial fatty acyl-coenzyme A oxidase. | The properties and subcellular localization of fatty acyl-CoA oxidase (FAO) were studied in rat heart homogenates. After differential centrifugation, FAO was sedimentable and enriched in a "light-mitochondrial" fraction. FAO had a pH optimum of 8-9. Among straight-chain, saturated fatty acyl-CoAs, the enzyme showed a m... | ['Acyl-CoA Oxidase', 'Animals', 'Cell Fractionation', 'Centrifugation, Density Gradient', 'Kinetics', 'Male', 'Myocardium', 'Oxidoreductases', 'Rats', 'Rats, Inbred Strains', 'Subcellular Fractions'] | 3,414,812 | [['D08.811.682.660.150.200', 'D12.776.331.149'], ['B01.050'], ['E05.242.251'], ['E05.181.724.336', 'E05.196.941.336'], ['G01.374.661', 'G02.111.490'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D08.811.682'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of the internal and external responsiveness of the Pressure Ulcer Scale for Healing (PUSH) tool for assessing acute and chronic wounds. | AIM: To examine the internal and external responsiveness of the Pressure Ulcer Scale for Healing (PUSH) tool for assessing the healing progress in acute and chronic wounds.BACKGROUND: It is important to establish the responsiveness of instruments used in conducting wound care assessments to ensure that they are able to... | ['Acute Disease', 'Adult', 'Aged', 'Chronic Disease', 'Empirical Research', 'Female', 'Hong Kong', 'Humans', 'Linear Models', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Prospective Studies', 'Reproducibility of Results', 'Severity of Illness Index', 'Wound Healing', 'Wounds and Injuries'] | 26,750,541 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.500'], ['H01.770.644.241'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500... | ['Diseases [C]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Quantitative studies on the accumulation of serum albumin and erythrocytes in mouse paw oedema induced by bradykinin or thermal injury. | The accumulation of 125I-labelled serum albumin and 51Cr-labelled erythrocytes was measured in mouse paw oedema induced by bradykinin or by heating the paw at 46.5 degrees. The extravasating fluid in bradykinin oedema consistently contained 50% of the albumin concentration of plasma, whereas the extravasating fluid ind... | ['Animals', 'Bradykinin', 'Burns', 'Edema', 'Epinephrine', 'Erythrocytes', 'Female', 'Inflammation', 'Mice', 'Serum Albumin', 'Time Factors'] | 638,029 | [['B01.050'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['C26.200'], ['C23.888.277'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical trial of tramadol by means of the "paired card" system (author's transl)]. | 1. 1-(m-Methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol (tramadol; Tramal) was administered i.v. to patients suffering from pain of various origins. Its efficacy and side effects were compared with those of metamizole and placebo. 2. Tramadol (100 mg) was as effective as metamizole (2.5 mg) and significantly mor... | ['Analgesics', 'Clinical Trials as Topic', 'Cyclohexanols', 'Dipyrone', 'Double-Blind Method', 'Drug Evaluation', 'Female', 'Humans', 'Male', 'Pain', 'Placebos', 'Statistics as Topic'] | 343,788 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['D03.383.129.539.850.077.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Catabolite repression and pyruvate metabolism in Escherichia coli. | A study was made of the reactions involved in the cellular regulatory function known as catabolite repression. These studies employed the glucose-repressible, beta-galactosidase system of Escherichia coli and involved an investigation of glucose dissimilation under cultural conditions capable of permitting or preventin... | ['Carbon Isotopes', 'Enzyme Repression', 'Escherichia coli', 'Galactosidases', 'Glucose', 'Oxygen Consumption', 'Pyruvates'] | 5,337,847 | [['D01.268.150.075', 'D01.496.123'], ['G05.308.320.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.450.410'], ['D09.947.875.359.448'], ['G03.680'], ['D02.241.755.812']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of sequential twin screw extrusion and fungal pretreatment to release soluble nutrients from soybean residue for carotenoid production. | BACKGROUND: Soybean residue (okara) is an agricultural by-product, which is rich in protein and fiber. This study evaluated a novel sequential process which combined fungal pretreatment (F) and twin screw extruder (E), to hydrolyze okara. The sequence of the pretreatment steps, and extruder at screw speeds 200 rpm (200... | ['Basidiomycota', 'Carotenoids', 'Fermentation', 'Food Handling', 'Plant Extracts', 'Soybeans', 'Waste Products'] | 30,411,355 | [['B01.300.179'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['G02.111.158.249', 'G03.191.249'], ['J01.576.423.200'], ['D20.215.784.500', 'D26.667'], ['B01.650.940.800.575.912.250.401.750'], ['D20.944', 'N06.850.460.710']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Correlation of MRI-derived adipose tissue measurements and anthropometric markers with prevalent hypertension in the community. | OBJECTIVES: To compare the correlations of MRI-derived adipose tissue measurements and anthropometric markers, respectively, with prevalent hypertension in a community-based sample, free of clinical cardiovascular disease.METHODS: MRI-derived adipose tissue measurements were obtained in 345 participants (143 women; age... | ['Aged', 'Area Under Curve', 'Blood Pressure', 'Body Mass Index', 'Female', 'Germany', 'Humans', 'Hypertension', 'Intra-Abdominal Fat', 'Liver', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pancreas', 'Pericardium', 'Prevalence', 'Subcutaneous Fat', 'Waist Circumference', 'Waist-Hip Ratio'] | 29,601,409 | [['M01.060.116.100'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A rare presentation of tuberculosis. | Primary involvement of the musculoskeletal system with tuberculosis is rare. We present a case of a young, immunocompetent woman with primary sternal tuberculosis. The disease led to destruction of the manubrium and a portion of the gladiolus and required extensive debridement and partial sternectomy, followed by muscu... | ['Adult', 'Biopsy', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Humans', 'Mycobacterium tuberculosis', 'Sternum', 'Surgical Flaps', 'Tomography, X-Ray Computed', 'Tuberculosis, Osteoarticular'] | 16,494,195 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds. | The calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) activates CAMK1, CAMK4, AMPK, and AKT, leading to numerous physiological responses. The deregulation of CAMKK2 is linked to several diseases, suggesting the utility of CAMKK2 inhibitors for oncological, metabolic and inflammatory indications. In this wor... | ['Animals', 'Benzimidazoles', 'Calcium-Calmodulin-Dependent Protein Kinase Kinase', 'Humans', 'Naphthalimides', 'Protein Kinase Inhibitors'] | 31,941,153 | [['B01.050'], ['D03.633.100.103'], ['D08.811.913.696.620.682.700.125.049', 'D12.644.360.100.049', 'D12.776.476.100.049'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.478.480', 'D03.383.621.808.612', 'D03.633.100.531.460', 'D04.615.638.596'], ['D27.505.519.389.755']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hyperhidrosis in na?ve purpose-bred beagle dogs (Canis familiaris). | This case study details the unusual clinical findings in a unique paw-pad disorder that recently emerged among 2 male and 1 female na?ve purpose-bred beagle dogs (Canis familiaris) newly received into our facility. During acclimation period physical examinations, the affected dogs demonstrated constantly moist, soft pa... | ['Animals', 'Breeding', 'Dog Diseases', 'Dogs', 'Female', 'Foot', 'Hyperhidrosis', 'Male', 'Skin'] | 21,640,037 | [['B01.050'], ['E05.820.150', 'G05.090'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['A01.378.610.250'], ['C17.800.946.350'], ['A17.815']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma ionic calcium levels following injection of chloride, gluconate, and gluceptate salts of calcium. | The ionic equivalency of three calcium salts was tested in 15 patients undergoing cardiac surgery with extracorporeal circulation. Of the three salts tested (chloride, gluconate, gluceptate), only calcium chloride showed a reproducible and highly significant relationship between the increase in total calcium and the in... | ['Buffers', 'Calcium', 'Calcium Chloride', 'Gluconates', 'Heart Arrest', 'Hematocrit', 'Hemoglobins', 'Heptoses', 'Humans', 'Oxygen', 'Potassium', 'Sodium', 'Sugar Acids'] | 1,263,543 | [['D27.720.470.280'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.146.300', 'D01.210.450.150.150'], ['D02.241.081.844.322', 'D02.241.511.902.322', 'D09.811.308'], ['C14.280.383'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.776.124.400', 'D12.776.422.316.762'], ['D09.947.875.28... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Deficiency in type I interferon signaling prevents the early interferon-induced gene signature in pancreatic islets but not type 1 diabetes in NOD mice. | Type I interferons (IFNs) have been implicated in the initiation of islet autoimmunity and development of type 1 diabetes. To directly test their involvement, we generated NOD mice deficient in type I IFN receptors (NOD.IFNAR1(-/-)). Expression of the type I IFN-induced genes Mx1, Isg15, Ifit1, Oas1a, and Cxcr4 was det... | ['Animals', 'Diabetes Mellitus, Type 1', 'Gene Expression', 'Histocompatibility Antigens Class I', 'Interferon Type I', 'Islets of Langerhans', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred NOD', 'Receptor, Interferon alpha-beta', 'Signal Transduction', 'Toll-Like Receptor 2', 'Toll-Like Receptor 9'] | 24,353,186 | [['B01.050'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G05.297'], ['D12.776.395.550.489', 'D12.776.543.550.439', 'D23.050.301.500.100', 'D23.050.705.552.100'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['A03.734.414', 'A06.300.414'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum 25-OH vitamin D level in treatment-na?ve systemic lupus erythematosus patients: Relation to disease activity, IL-23 and IL-17. | Objectives The aim of this study was to assess the vitamin D status in treatment-na?ve SLE patients and its association with clinical and laboratory markers of disease activity, including serum levels of IL-17 and IL-23. Methods Fifty-seven treatment-na?ve SLE patients along with 42 matched controls were included. SLED... | ['Adult', 'Antibodies, Antinuclear', 'Biomarkers', 'Case-Control Studies', 'Cross-Sectional Studies', 'Egypt', 'Female', 'Humans', 'Interleukin-17', 'Interleukin-23', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Prevalence', 'Vitamin D', 'Vitamin D Deficiency'] | 27,927,883 | [['M01.060.116'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.058.266.317'], ['B... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Influence of autogenous platelet concentrate on combined GTR/graft therapy in intrabony defects: a 7-year follow-up of a randomized prospective clinical split-mouth study. | OBJECTIVES: To investigate the influence of autogenous platelet concentrate (APC) on the long-term regeneration outcome 7 years after guided tissue regeneration (GTR) in deep intrabony periodontal defects.MATERIAL AND METHODS: In 25 patients, two deep contra-lateral intrabony defects were treated according to GTR (rand... | ['Alveolar Bone Loss', 'Blood Transfusion, Autologous', 'Bone Transplantation', 'Dental Plaque Index', 'Follow-Up Studies', 'Gingival Recession', 'Gingivitis', 'Guided Tissue Regeneration, Periodontal', 'Humans', 'Longitudinal Studies', 'Patient Compliance', 'Periodontal Attachment Loss', 'Periodontal Index', 'Periodon... | 22,486,272 | [['C05.116.264.150', 'C07.465.714.354.500'], ['E02.095.135.164'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The use of fruit extracts for production of apple chips with enhanced antioxidant activity | Background: Style and pace of life make consumers more willing to reach for snack products. This group of processed food includes, among others, fruit chips. Due to the increasing incidence of diseases associated with the excessive exposure to free radicals foods enriched with antioxidant compounds, eg. polyphenols, ca... | ['Antioxidants', 'Food, Fortified', 'Fruit', 'Malus', 'Plant Extracts', 'Polyphenols', 'Snacks'] | 28,646,833 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.203.300.515', 'J02.500.515'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.650.940.800.575.912.250.859.937.500.444'], ['D20.215.784.500', 'D26.667'], ['D02.455.426.559.389.657.715', 'D03.633.100.150.266.450.260.777'], ['G07.203.300.590.78... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Experience based on 800,000 newborn screening tests of the Budapest Phenylketonuria Centre. | 800 000 newborns were screened for hyperphenylalaninaemia by the Guthrie-test in the Budapest PKU Centre in the 10 and a half years since 1 May, 1973. The blood samples were taken from mature newborns on the fifth and from premature babies on the fourteenth day of life. All infants exhibiting a level equal to or exceed... | ['Child Health Services', 'Humans', 'Hungary', 'Infant, Newborn', 'Mass Screening', 'Phenylalanine', 'Phenylketonurias'] | 4,041,279 | [['N02.421.143.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['M01.060.703.520'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['D12.125.072.050.685', 'D12.125.142.666'], ['C10.228.140.1... | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prolonged third stage of labor: morbidity and risk factors. | Although retained placenta is a major cause of postpartum hemorrhage, there is no general agreement regarding when manual placental extraction is indicated to prevent hemorrhage. We sought to determine the following: 1) what duration of the third stage of labor is abnormal, 2) what duration is associated with complicat... | ['Female', 'Humans', 'Labor Stage, Third', 'Obstetric Labor Complications', 'Pregnancy', 'Regression Analysis', 'Risk Factors', 'Time Factors'] | 2,030,858 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326.500.110'], ['C13.703.420'], ['G08.686.784.769'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.72... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Changes in Pulmonary Function Following Image-Guided Stereotactic Lung Radiotherapy: Neither Lower Baseline Nor Post-SBRT Pulmonary Function Are Associated with Worse Overall Survival. | PURPOSE: To determine changes in pulmonary function brought about by lung stereotactic body radiation therapy (SBRT).METHODS: One hundred and twenty-seven patients were treated with lung SBRT using 48 to 60Gy in four to five fractions on a prospective trial. We obtained pulmonary function tests (PFTs) at baseline, 6 we... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Non-Small-Cell Lung', 'Cohort Studies', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Radiotherapy, Image-Guided', 'Respiratory Function Tests', 'Survival Analysis'] | 26,334,751 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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