Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Hyperopia and emergent literacy of young children: pilot study. | PURPOSE: To compare emergent literacy skills in uncorrected hyperopic and emmetropic children.METHODS: "Hyperopes" (>or=2.00 D sphere along the most hyperopic meridian; n=13; aged 67+/-13 mo) and "emmetropes" (<or=1.50 D sphere along the most hyperopic meridian; n=19; aged 58+/-12 mo) were tested for visual acuity (VA)... | ['Child', 'Child, Preschool', 'Cognition', 'Educational Status', 'Handwriting', 'Humans', 'Hyperopia', 'Pilot Projects', 'Reading', 'Visual Acuity', 'Visual Perception', 'Vocabulary'] | 18,043,422 | [['M01.060.406'], ['M01.060.406.448'], ['F02.463.188'], ['N01.824.196'], ['L01.559.423.906.539'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.744.479'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['L01.559.423.557'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Low frequency fatigue of quadriceps muscle after sustained maximum voluntary contractions. | Immediately after sustained maximum voluntary contractions for 60 s, greater quadriceps muscle fatigue and, especially, low frequency fatigue is observed. The results of our study have shown that immediately after the exercise there was a significant (P<0.05) decrease in muscle force induced by low (20 Hz) and high (50... | ['Adult', 'Analysis of Variance', 'Data Interpretation, Statistical', 'Electric Stimulation', 'Exercise', 'Humans', 'Isometric Contraction', 'Knee Joint', 'Male', 'Muscle Contraction', 'Muscle Fatigue', 'Muscle Relaxation', 'Muscle, Skeletal'] | 14,646,464 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.723.402'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
MinPD: distance-based phylogenetic analysis and recombination detection of serially-sampled HIV quasispecies. | A new computational method to study within-host viral evolution is explored to better understand the evolution and pathogenesis of viruses. Traditional phylogenetic tree methods are better suited to study relationships between contemporaneous species, which appear as leaves of a phylogenetic tree. However, viral sequen... | ['Algorithms', 'Chromosome Mapping', 'DNA, Viral', 'Evolution, Molecular', 'HIV', 'Linkage Disequilibrium', 'Phylogeny', 'Recombination, Genetic', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Species Specificity'] | 16,448,005 | [['G17.035', 'L01.224.050'], ['E05.393.183'], ['D13.444.308.568'], ['G05.045.250', 'G16.075.250'], ['B04.820.650.589.650.350'], ['G05.348.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.728'], ['E05.393.751'], ['E05.393.760.700'], ['G16.824']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Success of Minimally Invasive Pectus Excavatum Procedures (Modified Nuss) in Adult Patients (?30 Years). | BACKGROUND: Minimally invasive repair of pectus excavatum (MIRPE) has become standard for pediatric and young adult patients, but its use for older adults is controversial.METHODS: We retrospectively reviewed electronic medical records of adults (?18 years of age) who underwent MIRPE from January 1, 2010, through April... | ['Adult', 'Aged', 'Female', 'Funnel Chest', 'Humans', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Postoperative Care', 'Retrospective Studies', 'Sternum'] | 27,283,111 | [['M01.060.116'], ['M01.060.116.100'], ['C05.116.099.386', 'C05.660.386', 'C16.131.621.386'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.502'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500'... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytokine responses in very low birth weight infants receiving glutamine-enriched enteral nutrition. | OBJECTIVE: Very low birth weight (VLBW) infants receiving glutamine-enriched enteral nutrition may present with a lower infection rate, which may result from enhanced antimicrobial innate or Th1 cytokine responses. We investigated whether glutamine-enriched enteral nutrition in VLBW infants increased these cytokine res... | ['Birth Weight', 'CD28 Antigens', 'CD3 Complex', 'Cytokines', 'Double-Blind Method', 'Enteral Nutrition', 'Female', 'Gestational Age', 'Glutamine', 'Humans', 'Infant, Newborn', 'Infant, Very Low Birth Weight', 'Intensive Care, Neonatal', 'Interferon-gamma', 'Interleukins', 'Lipopolysaccharides', 'Male', 'Placebos', 'Tu... | 19,172,131 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['D12.776.543.750.705.222.500', 'D23.050.301.264.894.128', 'D23.101.100.894.128'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of contrast agent dose and diffusion coefficient measurement on vessel size index estimation. | OBJECTIVES: The goal of this study is to examine the effect of contrast agent (CA) dose and diffusion coefficient on the estimation of vessel size index (VSI).MATERIALS AND METHODS: Three groups of four participants were enrolled in this study and two different experiments were performed. Different dose of CA, namely 0... | ['Adult', 'Blood Vessels', 'Blood-Brain Barrier', 'Brain', 'Brain Neoplasms', 'Contrast Media', 'Diffusion Magnetic Resonance Imaging', 'Diffusion Tensor Imaging', 'Glioma', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Spectroscopy', 'Middle Aged'] | 31,270,714 | [['M01.060.116'], ['A07.015'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.825.500.150'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['C04.557.465.625.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Epithelial differentiation at the mucogingival junction: a stereological comparison of the epithelia of the vestibular gingiva and alveolar mucosa. | The epithelial lining of normal human vestibular gingiva and the adjoining alveolar mucosa was subjected to a comparative stereological analysis. Five biopsies collected from 11 to 12 year-old males and females were selected from a total of 14 specimens and, under standardized conditions, processed for light- and elect... | ['Adolescent', 'Alveolar Process', 'Cell Differentiation', 'Cell Nucleus', 'Cytoplasm', 'Epithelium', 'Female', 'Gingiva', 'Glycogen', 'Humans', 'Male', 'Microscopy, Electron', 'Mouth Mucosa'] | 509,505 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dried blood spots as a sampling technique for the quantitative determination of guanfacine in clinical studies. | BACKGROUND: Dried blood spot (DBS) technology was evaluated for the quantitative determination of guanfacine in human blood in clinical studies. A very sensitive DBS assay has been developed using HPLC coupled with an AB Sciex 5500 QTRAP® (Applied Biosystems/MDS Sciex, ON, Canada) MS system (LC-MS/MS) with a linear cal... | ['Adrenergic alpha-Agonists', 'Chromatography, Liquid', 'Clinical Trials as Topic', 'Dried Blood Spot Testing', 'Guanfacine', 'Humans', 'Liquid-Liquid Extraction', 'Male', 'Specimen Handling', 'Tandem Mass Spectrometry'] | 22,122,599 | [['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['E05.196.181.400'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E01.370.225.124.100.232', 'E05.200.124.100.232'], ['D02.078.370.465', 'D02.241.223.601.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Volatile organic compound testing of a population living near a hazardous waste site. | Accurate measures of individual exposure are critical in reducing misclassification and establishing scientifically valid associations between health outcomes and exposures to environmental contaminants. As part of a community health study, the Agency for Toxic Substances and Disease Registry conducted exposure testing... | ['Acetone', 'Adolescent', 'Adult', 'Aged', 'Butanones', 'Case-Control Studies', 'Child', 'Confidence Intervals', 'Environmental Exposure', 'Female', 'Hazardous Waste', 'Humans', 'Hydrocarbons', 'Hydrocarbons, Chlorinated', 'Industrial Waste', 'Kentucky', 'Male', 'Middle Aged', 'Odds Ratio', 'Reference Values', 'Samplin... | 8,792,300 | [['D02.522.064'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D02.522.296'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['N06.850.460.350'], ['D20.944.380', 'D27.888.426.500', 'N06.850.46... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ultra-thin porous glass membranes--an innovative material for the immobilization of active species for optical chemosensors. | In addition to polymers, porous glasses can be used for the immobilization of indicators, chromoionophores or enzymes. Advantages of these materials include, among others, the photochemical and thermal stability. Porous glass membranes (CPG) based on phase-separated alkali borosilicate glasses with thicknesses of 250-3... | ['Acridines', 'Coloring Agents', 'Glass', 'Hydrogen-Ion Concentration', 'Membranes, Artificial', 'Permeability', 'Porosity', 'Silicates', 'Spectrophotometry', 'Thymolphthalein', 'Water'] | 23,598,220 | [['D03.633.300.046'], ['D27.720.233'], ['J01.637.437'], ['G02.300'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G02.723'], ['G01.374.710'], ['D01.578.725', 'D01.837.725.700.760'], ['E05.196.712.726', 'E05.196.867.826'], ['D02.455.426.559.389.657.625.808'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.6... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Endometrial Carcinomas With Clear Cells: A Study of a Heterogeneous Group of Tumors Including Interobserver Variability, Mutation Analysis, and Immunohistochemistry With HNF-1â. | Endometrial clear cell carcinoma (CC) is an uncommon tumor and often carries a poor prognosis. It has histologic features that overlap with other endometrial carcinomas and is frequently misclassified. Accurate classification is crucial, however, to improve treatment options. The objectives of this study were (1) to as... | ['Adenocarcinoma, Clear Cell', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma, Endometrioid', 'Cystadenocarcinoma, Serous', 'DNA Mutational Analysis', 'Endometrial Neoplasms', 'Female', 'Hepatocyte Nuclear Factor 1-beta', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'Observer Variation'] | 25,851,704 | [['C04.557.470.200.025.045'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['C04.557.470.200.025.480.240', 'C04.5... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Antioxidant status and the risk of elevated C-reactive protein 12 years later. | BACKGROUND/AIMS: Low-grade inflammation is an independent risk factor for cardiovascular disease. Relationships between the antioxidant status and inflammatory biomarkers could give new insights into cardiovascular disease prevention. We investigated long-term associations between the antioxidant nutrient (vitamin C, á... | ['Antioxidants', 'Ascorbic Acid', 'C-Reactive Protein', 'Cohort Studies', 'Female', 'France', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Randomized Controlled Trials as Topic', 'Risk Factors', 'alpha-Tocopherol', 'beta Carotene'] | 25,377,123 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
ACL reconstruction: patellar tendon versus hamstring grafts--economical aspects. | The aim of the present investigation was to compare the costs for the use of patellar tendon versus hamstring tendons as grafts for anterior cruciate ligament (ACL) reconstruction including the different fixation methods. The background is that during recent years there has been a dramatic shift from patellar tendon to... | ['Adult', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Bone Screws', 'Bone-Patellar Tendon-Bone Grafting', 'Costs and Cost Analysis', 'Female', 'Humans', 'Male', 'Prospective Studies', 'Sweden', 'Tendons', 'Transplantation, Autologous'] | 16,570,193 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E02.095.147.725.065', 'E04.555.110.026.500', 'E04.680.101.026.500', 'E04.936.580.065'], ['N03.219.151'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Direct postoperative and follow-up results of transsphenoidal surgery in 19 acromegalic patients pretreated with octreotide compared to those in untreated matched controls. | In this study 19 patients were preoperatively treated with octreotide for 1-17 months (mean, 5 months), with doses from 150-1500 microg daily, and those patients were matched to 19 untreated patients with comparable tumor classification and preoperative serum GH concentrations. Octreotide was started at 300 microg dail... | ['Acromegaly', 'Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Hormones', 'Human Growth Hormone', 'Humans', 'Hypopituitarism', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Octreotide', 'Postoperative Complications', 'Postoperative Period', 'Premedication', 'Prospective Studies', 'Sphenoid Bone', 'Treatment Failure'... | 10,522,994 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D06.472', 'D27.505.696.399.472'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.6... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synergistic effect of bisphosphonate and docetaxel on the growth of bone metastasis in an animal model of established metastatic bone disease. | Bisphosphonates decrease bone resorption and reduce significantly the rate of skeletal complications in patients with metastatic bone disease. Bisphosphonates have also been shown to exhibit antitumor activity in vitro but in vivo results have been equivocal. In the present study, we investigated the effects of bisphos... | ['Animals', 'Antineoplastic Agents', 'Bone Density Conservation Agents', 'Bone Neoplasms', 'Breast Neoplasms', 'Diphosphonates', 'Disease Models, Animal', 'Docetaxel', 'Drug Synergism', 'Female', 'Humans', 'Mice', 'Mice, Nude', 'Neoplasm Metastasis', 'Taxoids', 'Xenograft Model Antitumor Assays'] | 18,989,771 | [['B01.050'], ['D27.505.954.248'], ['D27.505.696.242'], ['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['D02.705.429.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['G07.690.773.968.477'], ['B01.050.150.900.649.313.988.400.112.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pattern of serum immunoreactivity against breast cancer cell lysates may predict severity of disease in breast cancer patients. | Humoral tumor-specific immunity has been investigated as a potential tool to identify tumor-associated antigens and evaluate cancer diagnosis and prognosis. Using SDS-PAGE and western blotting techniques we investigated the humoral immune response against tumor cell antigens in 36 breast cancer patients, 17 node-positi... | ['Antibodies, Neoplasm', 'Antigens, Neoplasm', 'Blotting, Western', 'Breast Neoplasms', 'Cell Line, Tumor', 'Female', 'Humans', 'Immunoassay', 'Immunoglobulin G', 'Predictive Value of Tests', 'Severity of Illness Index', 'Subcellular Fractions'] | 17,440,722 | [['D12.776.124.486.485.114.240', 'D12.776.124.790.651.114.240', 'D12.776.377.715.548.114.240'], ['D23.050.285'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The burden of metabolic diseases amongst HIV positive patients on HAART attending The Johannesburg Hospital. | South Africa has the highest prevalence of human immunodeficiency virus (HIV) infection in the world. The improved life expectancy, due to the recent introduction of highly active antiretroviral therapy (HAART), may lead to an increased health burden related to metabolic disorders, resulting in an increased pressure on... | ['Adult', 'Antiretroviral Therapy, Highly Active', 'Cross-Sectional Studies', 'Diabetes Mellitus', 'Dyslipidemias', 'Female', 'HIV Infections', 'Humans', 'Hypertension', 'Male', 'Metabolic Diseases', 'Middle Aged', 'Multivariate Analysis', 'Obesity', 'Prevalence', 'Risk Factors', 'Sex Factors', 'South Africa', 'Young A... | 21,631,427 | [['M01.060.116'], ['E02.319.310.075'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750', 'C19.246'], ['C18.452.584.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Endoscopic application of EGF-chitosan hydrogel for precipitated healing of GI peptic ulcers and mucosectomy-induced ulcers. | The gastrointestinal (GI) endoscopy has become a standard diagnostic tool for GI ulcers and cancer. In this study we studied endoscopic application of epidermal growth factor-containing chitosan hydrogel (EGF-CS gel) for treatment of GI ulcer. We hypothesized that directional ulcer-coating using EGF-CS gel via endoscop... | ['Animals', 'Chitosan', 'Disease Models, Animal', 'Endoscopy, Gastrointestinal', 'Epidermal Growth Factor', 'Female', 'Gastric Mucosa', 'Hydrogels', 'Peptic Ulcer', 'Rabbits', 'Swine', 'Wound Healing'] | 24,338,378 | [['B01.050'], ['D05.750.078.139.500', 'D09.698.211.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['A03.556.875.875.440', 'A10.615.55... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of proton-pumping nicotinamide nucleotide transhydrogenase in mouse, human brain and C elegans. | Proton-translocating nicotinamide nucleotide transhydrogenase is located in the mitochondrial inner membrane and catalyzes the reduction of NADP(+) by NADH to NADPH and NAD(+). The present investigation describes the expression of the transhydrogenase gene in various mouse organs, subsections of the human brain and Cae... | ['Animals', 'Blotting, Northern', 'Brain', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'Female', 'Green Fluorescent Proteins', 'Humans', 'Luminescent Proteins', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Microscopy, Fluorescence', 'NADP Transhydrogenases', 'Neurons', 'Promoter Regions, Genetic', 'Reverse ... | 12,223,207 | [['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A08.186.211'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['D12.776.532.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.532'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Respiratory pathogens in bronchoalveolar lavage in a Puerto Rican population infected with the human immunodeficiency virus. | OBJECTIVE: To describe the respiratory pathogens found in the bronchoalveolar lavage of a Puerto Rican population infected with the human immunodeficiency virus (HIV).BACKGROUND: Empirical treatment is an accepted strategy for management of HIV-related pneumonia, but it is usually recommended for countries that have kn... | ['Adult', 'Bronchoalveolar Lavage Fluid', 'Female', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'Puerto Rico'] | 16,331,860 | [['M01.060.116'], ['E05.927.100.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.084.900.750', 'Z01.639.880.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Effects of serotonin and serotonin analogs on posture and agonistic behavior in crayfish. | Exogenous serotonin has been shown to induce an elevated, flexed posture in crustaceans and has also been hypothesized to enhance aggressive behavior. We conducted three experiments to further investigate the effects of serotonin and serotonin analogs on posture and agonistic behavior in the crayfish Procambarus clarki... | ['Agonistic Behavior', 'Animals', 'Astacoidea', 'Female', 'Male', 'Posture', 'Receptors, Serotonin', 'Serotonin', 'Serotonin Receptor Agonists'] | 11,800,033 | [['F01.145.126.125.100'], ['B01.050'], ['B01.050.500.131.365.190.070'], ['G11.427.695'], ['D12.776.543.750.670.800', 'D12.776.543.750.695.800', 'D12.776.543.750.720.850'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.050.650'], ['D27.505.519.625.850.800', 'D27.505.696.577.850.800']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ATP induces the release of IL-1 from LPS-primed cells in vivo. | The secretion of IL-1 from murine macrophages in vitro is an inefficient process that is distinct from those of other cytokines such as IL-6. We have therefore studied this process in vivo to see if these differences are maintained. Intraperitoneal injection of LPS in mice induced production and release of IL-6 into th... | ['Acetylglucosaminidase', 'Adenosine Triphosphate', 'Animals', 'Blotting, Western', 'Cells, Cultured', 'Enzyme-Linked Immunosorbent Assay', 'Interleukin-1', 'L-Lactate Dehydrogenase', 'Lipopolysaccharides', 'Macrophages, Peritoneal', 'Male', 'Mice'] | 7,876,552 | [['D08.811.277.450.483.180.500'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surrogate Motherhood and Woman Dignity]. | Motherhood by subrogation is an issue that directly affects human rights and, ultimately, human dignity. Therefore, if we want to give an adequate response to this issue, it is essential to reflect on how this practice affects the dignity and rights of the people involved in it and, more specifically, the pregnant moth... | ['Female', 'Human Rights', 'Humans', 'Personhood', 'Pregnancy', 'Pregnant Women', 'Surrogate Mothers'] | 28,621,959 | [['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.752.566.479.660', 'N05.350.917'], ['G08.686.784.769'], ['M01.975.807'], ['F01.829.263.500.320.892', 'I01.880.853.150.500.340.892', 'M01.620.892']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Expression of agouti-related peptide, neuropeptide Y, pro-opiomelanocortin and the leptin receptor isoforms in fetal mouse brain from pregnant dams on a protein-restricted diet. | Expression of agouti-related peptide, neuropeptide Y, pro-opiomelanocortin and leptin receptor isoforms were found in fetal mouse brain at embryonic day 12 (E12). Levels of expression for these genes were altered in brains of E12 fetuses from pregnant dams on a protein-restricted diet, suggesting that the fetal brain i... | ['Agouti-Related Protein', 'Animals', 'Brain', 'Diet, Protein-Restricted', 'Female', 'Fetus', 'Gene Expression Regulation, Developmental', 'Intercellular Signaling Peptides and Proteins', 'Mice', 'Neuropeptide Y', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Pro-Opiomelanocortin', 'Proteins', 'Receptors, Cell Sur... | 16,099,070 | [['D12.644.276.074', 'D12.776.467.074', 'D23.529.074'], ['B01.050'], ['A08.186.211'], ['E02.642.249.280', 'G07.203.650.240.280'], ['A16.378'], ['G05.308.310'], ['D12.644.276', 'D12.776.467', 'D23.529'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.400.500', 'D12.776.631.650.500'], ['G08.686.784.769'], ['C13.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduction of maternal adrenal steroids results in increased VEGF protein without increased eNOS in the ovine placenta. | Fetal sheep studies have shown that reduced maternal cortisol or aldosterone levels alter placental morphology, with a reduction in placental blood flow. We have now tested the hypothesis that changes in placental morphology with relative adrenal hypoadrenalism are associated with changes in vascular endothelial growth... | ['Aldosterone', 'Animals', 'Female', 'Hydrocortisone', 'Nitric Oxide Synthase Type III', 'Placenta', 'Pregnancy', 'RNA, Messenger', 'Sheep, Domestic', 'Up-Regulation', 'Vascular Endothelial Growth Factor A'] | 17,113,146 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['B01.050'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D08.811.682.664.500.772.750'], ['A16.710'], ['G08.686.784.769'], ['D13.444.735.544'], ['B01.050.150.900.649.313.500.380.791.150'], ['G02.111.905', 'G05.308.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing HIV testing and linkage to care activities and providing academic support to public health authorities in Houston, TX. | BACKGROUND: Health departments often have little knowledge of HIV testing and linkage activities outside of those they directly fund. Many health departments also have limited access to outside academic expertise.METHODS: We conducted a survey of health organizations in the Houston/Harris County region to determine the... | ['AIDS Serodiagnosis', 'HIV Infections', 'Health Care Surveys', 'Health Personnel', 'Health Policy', 'Health Services Accessibility', 'Humans', 'Mass Screening', 'Public Health', 'Texas', 'Workforce'] | 24,126,451 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Effects of cranial radiation on hearing in children with acute lymphocytic leukemia. | We serially assessed the hearing sensitivity of 61 children with acute lymphocytic leukemia who were admitted to our Total Therapy IX study between December, 1975, and July, 1977. Their treatment included combined chemotherapy, 2,400 rads of cranial radiation, and intrathecal methotrexate. Subjects initially received a... | ['Adolescent', 'Adult', 'Audiometry, Pure-Tone', 'Child', 'Child, Preschool', 'Cobalt Radioisotopes', 'Hearing', 'Hearing Loss, Sensorineural', 'Humans', 'Leukemia, Lymphoid', 'Radiation Injuries', 'Skull'] | 6,928,463 | [['M01.060.057'], ['M01.060.116'], ['E01.370.382.375.060.055'], ['M01.060.406'], ['M01.060.406.448'], ['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['C09.218.458.341.887', 'C10.597.751.418.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cyclic tensile force up-regulates BMP-2 expression through MAP kinase and COX-2/PGE2 signaling pathways in human periodontal ligament cells. | Periodontal ligament cells play important roles in the homeostasis of periodontal tissue by mechanical stress derived from mastication, such as tension, compression, fluid shear, and hydrostatic force. In the present study, we showed that cyclic tensile force increased the gene expression level of bone morphogenetic pr... | ['Adult', 'Bite Force', 'Bone Morphogenetic Protein 2', 'Butadienes', 'Calcification, Physiologic', 'Cells, Cultured', 'Cyclooxygenase 2', 'Cyclooxygenase Inhibitors', 'Dinoprostone', 'Extracellular Signal-Regulated MAP Kinases', 'Female', 'Flavonoids', 'Humans', 'Imidazoles', 'Male', 'Mastication', 'Molar, Third', 'Ni... | 24,561,081 | [['M01.060.116'], ['E06.276.125'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['D02.455.326.271.665.146.240'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['A11.251'], ['D08.811.600.720.750'], ['D27.505.519.389.310', 'D27.505.696.663.850.014... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A psychoeducational program for caregivers of the chronic mentally ill residing in community residencies. | The objective of this study was to develop a psychoeducational program for caregivers of the chronically mentally ill residing in community residencies. An evaluative component was added to determine how well the program was received by caregivers and what impact the program had on the residents. A total of 20 caregive... | ['Aged', 'Aged, 80 and over', 'Caregivers', 'Education', 'Female', 'Humans', 'Male', 'Maryland', 'Mental Disorders', 'Middle Aged', 'Outcome Assessment, Health Care', 'Psychotic Disorders', 'Residential Facilities', 'Schizophrenia'] | 9,693,867 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['I02'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['F03'], ['M01.060.116.630'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['F03.700.675']... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Chromosome 1q loss of heterozygosity frequently occurs in sporadic insulinomas and is associated with tumor malignancy. | The pathogenesis of sporadic insulinomas is not clear, and there are no reliable genetic determinants that are useful to distinguish malignant and benign forms of this tumor. It was reported that 1q LOH might contribute to pathogenesis in gastrinomas and was correlated with tumor progression. However, little data are a... | ['Adolescent', 'Adult', 'Aged', 'Chromosome Mapping', 'Chromosomes, Human, Pair 1', 'DNA, Neoplasm', 'Female', 'Humans', 'Insulin', 'Insulinoma', 'Loss of Heterozygosity', 'Male', 'Microsatellite Repeats', 'Middle Aged', 'Pancreatic Neoplasms'] | 15,900,598 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.393.183'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ['D13.444.308.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C04.557.470.035.100.852', 'C04.588.274.761.249.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The role of ultrasonic and cytogenetic markers in prenatal diagnostics]. | As a result of leadthrough 288 invasive manipulations with the use of cytogenetic and molecular-cytogenetic methods we have found 16 different disorders in the fetus karyotype of the expectant mothers of high risk groups. For the most part the Down syndrome and the Shereshevsky-Therner syndrome were detected among aneu... | ['Amniocentesis', 'Biomarkers', 'Chromosome Disorders', 'Cytogenetic Analysis', 'Female', 'Fetal Diseases', 'Gestational Age', 'Humans', 'Pregnancy', 'Prenatal Diagnosis', 'Ultrasonography, Prenatal'] | 17,243,374 | [['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['D23.101'], ['C16.131.260', 'C16.320.180'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.393.285'], ['C13.703.277', 'C16.300'], ['G07.345... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CAR-3, a monoclonal antibody-defined antigen expressed on human carcinomas. | Several monoclonal antibodies were raised against the human epidermoid carcinoma line A 431. The antibody produced by clone AR-3, when tested in enzyme-linked immunosorbent assay, was found to react with the cell line used as immunogen, the human gastric carcinoma line KATO III, the colon carcinoma line HT29, and the o... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, Neoplasm', 'Antigens, Surface', 'Carcinoembryonic Antigen', 'Cell Line', 'Epitopes', 'Gastrointestinal Neoplasms', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Neoplasms'] | 2,413,998 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.285'], ['D23.050.301'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['A11.251.210'], ['D23.050.550'], ['C04.588.274.476', 'C06.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Causes of vision impairment and assessment of need for low vision services for students of blind schools in Nepal. | BACKGROUND: The present study is first of its kind to evaluate causes of visual impairment of blind students in Nepal and assess their need for low vision rehabilitation services.AIM: To evaluate causes of vision impairment of students enrolled in blind schools in Nepal and assess the need for low vision rehabilitation... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Eyeglasses', 'Female', 'Health Surveys', 'Humans', 'Male', 'Nepal', 'Quality of Life', 'Vision Disorders', 'Vision, Low', 'Visually Impaired Persons', 'Young Adult'] | 19,483,452 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E07.632.500.300'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.674'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['C10.597.751.941'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Immunohistological detection of human cytotoxic/suppressor T cells using antibodies to a CD8 peptide sequence. | AIMS: To evaluate whether cytotoxic/suppressor T cells can be detected in paraffin wax embedded human tissue samples using antibodies to a synthetic CD8 peptide sequence.METHODS: Polyclonal and monoclonal antibodies were raised against a 13 amino acid peptide sequence from the cytoplasmic portion of the alpha chain of ... | ['Amino Acid Sequence', 'Antibodies, Monoclonal', 'CD8 Antigens', 'Humans', 'Immunohistochemistry', 'Molecular Sequence Data', 'Palatine Tonsil', 'Spleen', 'T-Lymphocytes, Cytotoxic', 'T-Lymphocytes, Regulatory'] | 1,479,035 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.894.108', 'D23.101.100.894.108'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Determination of the exercise intensity corresponding with maximal lactate steady state in high-level basketball players. | The purpose of the present study was to define the maximal lactate steady state (MLSSmeas) in high-level male basketball players and to compare it with the lactate turnpoint (LTP) and the respective point derived form a prediction method (MLSScal). Twelve high-level basketball players underwent one maximal and several ... | ['Adult', 'Athletes', 'Basketball', 'Exercise Test', 'Humans', 'Lactic Acid', 'Male', 'Oxygen Consumption'] | 30,126,295 | [['M01.060.116'], ['M01.072'], ['I03.450.642.845.117'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['G03.680']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Simple dynamic model of the human blood pressure regulatory system as based on the orthostatic load sequence]. | The two statistical parameter estimation methods, the recursive least squares and the recursive generalized least squares, are dealt with briefly. An additional noncorrelated disturbance is necessary for unbiased parameter estimation in the closed-loop system. The disturbance is realized by an orthostatic load sequence... | ['Adolescent', 'Adult', 'Blood Pressure', 'Blood Pressure Determination', 'Female', 'Heart Rate', 'Humans', 'Male', 'Models, Biological', 'Posture', 'Temporal Arteries'] | 1,022,134 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['G11.427.695'], ['A07.015.114.228.868']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
XPF polymorphism toward lung cancer susceptibility and survival in patients treated with platinum-based chemotherapy. | AIM: To evaluate the association of three XPF polymorphic variants (673 C>T, 11985 A>G, G415A) with lung cancer, overall survival and clinical response in North Indians.METHODS: Genotyping was performed using PCR-restriction fragment length polymorphism.RESULTS: A total of 673 C>T polymorphism was associated with 1.5-f... | ['Adult', 'Aged', 'Carboplatin', 'Cisplatin', 'DNA-Binding Proteins', 'Disease-Free Survival', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Prognosis'] | 29,741,112 | [['M01.060.116'], ['M01.060.116.100'], ['D02.257.125'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D12.776.260'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.393.385'], ['C23.550.291.687.500', 'G0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Foci of stromal melanocytes (so-called blue naevus) of the uterine cervix in Japanese women. | Foci of stromal melanocytes (FSM) of the uterine cervix have been known as extra-cutaneous "blue naevus". However macroscopic and histological findings suggest that FSM of the cervix are analogous to dermal melanocytosis, rather than to cutaneous blue naevus and the lesions are more appropriately called stromal melanoc... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Immunohistochemistry', 'Infant', 'Infant, Newborn', 'Japan', 'Melanocytes', 'Melanoma', 'Middle Aged', 'Nevus, Pigmented', 'S100 Proteins', 'Uterine Cervical Neoplasms'] | 2,024,454 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
An efficient method for the extraction of high-quality fungal total RNA to study the Mycosphaerella fijiensis-Musa spp. Interaction. | Efficient RNA isolation is a prerequisite for gene expression studies and it has an increasingly important role in the study of plant-fungal pathogen interactions. However, RNA isolation is difficult in filamentous fungi. These organisms are notorious for their rigid cell walls and the presence of high levels of carboh... | ['Ascomycota', 'Host-Pathogen Interactions', 'Molecular Biology', 'Musa', 'Mycelium', 'Plant Diseases', 'Plant Leaves', 'RNA, Fungal'] | 18,679,833 | [['B01.300.107'], ['G06.462', 'G16.527.200'], ['H01.158.201.636', 'H01.158.273.343.595', 'H01.181.122.650'], ['B01.650.940.800.575.912.250.618.937.555.500'], ['A19.687'], ['G15.610'], ['A18.024.812'], ['D13.444.735.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Changes in the extracellular pH value and its effect on the intracellular pH value of tissues]. | The behavior of intracellular pH in different tissues during variation of plasma pH by respiratory and metabolic changes was studied in nephrectomized, unrestrained male Sprague-Dawley rats. The following conclusions can be made: pHi is influenced by respiratory and non-respiratory disturbances of the extracellular aci... | ['Acid-Base Equilibrium', 'Acidosis', 'Acidosis, Respiratory', 'Alkalosis', 'Animals', 'Bicarbonates', 'Body Fluids', 'Brain', 'Carbon Dioxide', 'Carbonic Anhydrase Inhibitors', 'Extracellular Space', 'Humans', 'Hydrogen-Ion Concentration', 'Intracellular Fluid', 'Liver', 'Male', 'Muscles', 'Rats', 'Rats, Inbred Strain... | 6,423,502 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['C18.452.076.176'], ['C08.618.846.093', 'C18.452.076.176.310'], ['C18.452.076.354'], ['B01.050'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['A12.207'], ['A08.186.211'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D27.505.519.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic kidney disease and diabetes associated with long-term outcomes in patients receiving percutaneous coronary intervention. | BACKGROUND: The effect of diabetes mellitus (DM) and chronic kidney disease (CKD) on long-term outcomes in patients receiving percutaneous coronary intervention (PCI) is unclear.METHODS: A total of 1394 patients who underwent PCI were prospectively enrolled and divided into 4 groups according to the presence or absence... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Glucose', 'Cause of Death', 'Comorbidity', 'Coronary Angiography', 'Diabetes Mellitus', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Percutaneous Coronary Intervention', 'Prospective Studies', 'Renal... | 28,893,175 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D09.947.875.359.448.500'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
hsa‑miR‑24 suppresses metastasis in nasopharyngeal carcinoma by regulating the c‑Myc/epithelial‑mesenchymal transition axis. | Distant metastasis is the major contributor to treatment failure and mortality in patients with nasopharyngeal carcinoma (NPC). The lack of effective treatment strategies for metastatic NPC is the major cause for the low survival rate. Therefore, it is crucial to understand the molecular mechanisms underlying NPC metas... | ['Aged', 'Carcinoma', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Epithelial-Mesenchymal Transition', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'MicroRNAs', 'Middle Aged', 'Nasopharyngeal Carcinoma', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Proto-Oncogene Proteins c-m... | 30,226,609 | [['M01.060.116.100'], ['C04.557.470.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.356.500'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['M01.060.1... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ICI 206,970: a novel calcium channel blocker with eukalemic diuretic activity. | ICI 206,970 is a novel eukalemic diuretic from the aminomethylphenol pyrazine series which exhibited a calcium antagonist profile. The isolated rat aorta evaluation and dihydropyridine ligand [3H]-PN 200-110 binding studies demonstrated that ICI 206,970, like verapamil and nifedipine, inhibits vascular smooth muscle to... | ['Animals', 'Aorta', 'Calcium Channel Blockers', 'Cardiomegaly', 'Coronary Circulation', 'Diuretics', 'Dogs', 'Electrocardiography', 'Hypertension', 'In Vitro Techniques', 'Male', 'Pyrazines', 'Radioligand Assay', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Rats, Sprague-Dawley'] | 8,278,459 | [['B01.050'], ['A07.015.114.056'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['C14.280.195', 'C23.300.775.250'], ['G09.330.100.324'], ['D27.505.696.560.500'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C14.907.489'], ['E05.481'], ['D03.383.679... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endoscopic sphincter of Oddi manometry in healthy volunteers. | This study evaluates the endoscopic manometric findings within the sphincter of Oddi (SO) in nine healthy volunteers premedicated with atropine 1 h before and with diazepam during the investigation. We measured the bile duct sphincter in seven persons and the pancreatic duct sphincter in two. A hydraulic capillary infu... | ['Adolescent', 'Adult', 'Aged', 'Ampulla of Vater', 'Endoscopy', 'Female', 'Humans', 'Male', 'Manometry', 'Middle Aged', 'Reference Values', 'Sphincter of Oddi'] | 3,576,130 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['M01.060.116.630'], ['E05.978.810'], ['A03.159.183.079.300.950.600'... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The contribution of forensic psychiatry in the determination of punishable guilt]. | As part of the consultative discussions between members of the Supreme Court and workers at the Department of Forensic Psychiatry, G.D.R. Institute of Psychiatrists and Neurologists, problems are being dealt here with, which have been discussed by the present authors as early as in 1972. These are questions arising in ... | ['Crime', 'Emotions', 'Expert Testimony', 'Forensic Psychiatry', 'Germany, East', 'Guilt', 'Humans', 'Mental Disorders', 'Motivation', 'Personality'] | 451,091 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Limited heterogeneity in the T-cell receptor V-gene usage in lymphocytes infiltrating human colorectal tumours. | The presence of T lymphocytes in solid tumours may reflect an ongoing immune response against the transformed cells. We have used polymerase chain reaction (PCR) technology to investigate the T-cell receptor variable-region gene (V-gene) usage in freshly isolated tumour-infiltrating lymphocytes (TILs) to look for a pos... | ['Adenocarcinoma', 'Antigens, CD', 'Colonic Neoplasms', 'Colorectal Neoplasms', 'DNA', 'Humans', 'Immunophenotyping', 'Lymphocytes, Tumor-Infiltrating', 'Polymerase Chain Reaction', 'Receptors, Antigen, T-Cell, alpha-beta', 'Rectal Neoplasms', 'T-Lymphocytes'] | 8,198,973 | [['C04.557.470.200.025'], ['D23.050.301.264.035', 'D23.101.100.110'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Toward the fast blind docking of a peptide to a target protein by using a four-body statistical pseudo-potential. | In vitro molecular evolution creates a lot of peptide aptamers that bind to each target protein. In many cases, their binding sites on a protein surface are not known. Then, predicting the binding sites through computation within a reasonable time is desirable. With this aim, we have developed a novel system of fast an... | ['Algorithms', 'Binding Sites', 'Computer Simulation', 'Databases, Protein', 'Models, Molecular', 'Peptides', 'Protein Conformation', 'Proteins'] | 19,939,735 | [['G17.035', 'L01.224.050'], ['G02.111.570.120'], ['L01.224.160'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['E05.599.595'], ['D12.644'], ['G02.111.570.820.709'], ['D12.776']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison between hemofiltration and hemodiafiltration in a long-term prospective cross-over study. | BACKGROUND: The objective of the study was to compare the convective treatment modes, on-line hemofiltration (HF) and on-line hemodiafiltration (HDF), regarding cardiovascular tolerance and effects on blood pressure, when applied under similar conditions in stable dialysis patients.METHODS: 39 clinically stable dialysi... | ['Blood Pressure', 'Cross-Over Studies', 'Electric Impedance', 'Female', 'Hemodiafiltration', 'Hemofiltration', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged'] | 15,365,963 | [['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G01.358.500.249.277.350'], ['E02.870.300.200', 'E02.912.800.200', 'E04.292.471.350'], ['E02.870.225', 'E04.292.471'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.96... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Helicobacter muricola sp. nov., a novel Helicobacter species isolated from the ceca and feces of Korean wild mouse (Mus musculus molossinus). | A slowly growing microaerophilic Helicobacter strain was isolated from the ceca and fecal pellets of Korean wild mice (Mus musculus molossinus). This bacterial strain possessed a pair of nonsheathed bipolar flagella, was positive for urease, catalase and oxidase, and reduced nitrate to nitrite. It proved susceptible to... | ['Animals', 'Bacterial Proteins', 'Bacterial Typing Techniques', 'Cecum', 'DNA, Bacterial', 'DNA, Ribosomal', 'Feces', 'Female', 'Flagella', 'Helicobacter', 'Korea', 'Male', 'Molecular Sequence Data', 'Muridae', 'Phylogeny', 'Polymerase Chain Reaction', 'RNA, Bacterial', 'RNA, Ribosomal, 16S', 'Species Specificity'] | 12,007,652 | [['B01.050'], ['D12.776.097'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['D13.444.308.212'], ['D13.444.308.475'], ['A12.459'], ['A11.284.180.290'], ['B03.440.500', 'B03.660.150.235.500.250'], ['Z01.252.474.557', 'Z01.586.407'], ['L01.453.245.667'], ['B01.050.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Geographicals [Z]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
The effect of the process variables on the HPLC separation of tricyclic neuroleptics on a calixarene-bonded stationary phase. | The chromatographic behavior of a new HPLC-stationary phase with supramolecular selectors on the basis of calixarenes is described for the separation of nine tricyclic neuroleptics. The effects of different chromatographic conditions (buffer system, pH-value, type and content of organic modifier, injection volume) on t... | ['Antidepressive Agents, Tricyclic', 'Buffers', 'Calixarenes', 'Chromatography, High Pressure Liquid', 'Hydrogen-Ion Concentration', 'Indicators and Reagents', 'Methanol', 'Piperazines', 'Solvents', 'Spectrophotometry, Ultraviolet'] | 15,801,670 | [['D27.505.954.427.700.122.055'], ['D27.720.470.280'], ['D04.345.025'], ['E05.196.181.400.300'], ['G02.300'], ['D27.720.470.410'], ['D02.033.623'], ['D03.383.606'], ['D27.720.844'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monitoring the bacteriological quality of potable waters in hospital. | We report a survey of the bacteriological quality of potable waters from hospitals. In the 12-month period February 1986 to January 1987, 646 samples were examined from 25 hospitals. Coliforms were isolated from eight (1.2%) samples, received from three hospitals. These hospitals did not, therefore, satisfy the Europea... | ['Enterobacteriaceae', 'Maintenance and Engineering, Hospital', 'Sanitary Engineering', 'United Kingdom', 'Water Microbiology', 'Water Supply'] | 2,907,334 | [['B03.440.450.425', 'B03.660.250.150'], ['N02.278.216.500.968.450', 'N02.628.472', 'N04.452.442.452.422.450'], ['H02.229.656', 'J01.293.821', 'N06.850.780.200.800.800', 'N06.850.860.510'], ['Z01.542.363'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['J01.293.821.500']] | ['Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Endoscopic submucosal tumor biopsy using Stiegmann-Goff endoscopic ligator. | Endoscopic biopsy is an important tool for histological diagnosis of lesions residing in gastrointestinal tracts. However, it is less useful in submucosal lesions due to the existence of normal overlying mucosa. We developed a new and safe technique for the diagnosis of submucosal tumor using Stiegmann-Goff endoscopic ... | ['Biopsy', 'Endoscopy, Gastrointestinal', 'Gastric Mucosa', 'Gastrointestinal Neoplasms', 'Humans', 'Intestinal Mucosa', 'Ligation'] | 11,061,573 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C04.588.274.476', 'C06.301.371', 'C0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Basic surgical skills testing for junior residents: current views of general surgery program directors. | BACKGROUND: The American College of Surgeons/Association of Program Directors in Surgery Phase 1 Curriculum (ACS/APDS) includes evaluation of basic surgical skills for junior residents. It is unclear if basic surgical skills evaluation is incorporated into residency curricula or used for resident advancement decisions.... | ['Clinical Competence', 'Curriculum', 'Education, Medical, Graduate', 'Educational Measurement', 'Humans', 'Internship and Residency', 'Surgical Procedures, Operative', 'Task Performance and Analysis'] | 21,356,489 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.337.350', 'I02.358.399.350'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['E04'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Rodent allergen in Los Angeles inner city homes of children with asthma. | Recent studies have examined the presence of mouse allergen in inner city children with asthma. Researchers have found high levels of rodent allergen in homes sampled in the northeast and midwest United States, but there has been considerable variation between cities, and there have been few studies conducted in wester... | ['Adolescent', 'Allergens', 'Animals', 'Asthma', 'Child', 'Cohort Studies', 'Dust', 'Environmental Exposure', 'Environmental Monitoring', 'Family Characteristics', 'Hispanic Americans', 'Housing', 'Humans', 'Los Angeles', 'Mice', 'Poverty Areas', 'Urban Population'] | 18,004,665 | [['M01.060.057'], ['D23.050.063'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D20.633.222'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['F01.829.263.315', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Geogr... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Parkin transcript variants in rat and human brain. | Alternative splicing has an important role in expanding protein diversity. We have identified complementary DNA species from adult rat and fetal human brain encoding seven new splice variants of parkin, a gene mutated in autosomal recessive juvenile parkinsonism (ARJP). Alternative splicing affects almost all previousl... | ['Alternative Splicing', 'Animals', 'Brain', 'Genetic Variation', 'Humans', 'Parkinson Disease', 'Rats', 'Transcription, Genetic', 'Ubiquitin-Protein Ligases'] | 15,453,267 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['A08.186.211'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['G02.111.873', 'G05.297.700'], ['D08.811.46... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microsurgical removal of a vestibular schwannoma after stereotactic radiosurgery: surgical and pathologic findings. | OBJECTIVE: The objective of this study was to provide objective evidence of the enhanced difficulty of preserving the facial nerve in patients who need microsurgery after failed stereotactic radiosurgery (SRS) of vestibular schwannoma.STUDY DESIGN: This study was a retrospective case review.SETTING: A tertiary care ref... | ['Adult', 'Cranial Nerve Neoplasms', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Microsurgery', 'Neurilemmoma', 'Postoperative Care', 'Radiosurgery', 'Retrospective Studies', 'Vestibular Nerve'] | 10,337,979 | [['M01.060.116'], ['C04.588.614.300', 'C04.588.614.596.240', 'C10.292.225', 'C10.551.360', 'C10.551.775.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E04.494', 'E05.591.580'], ['C04.557.465.625.650.595', 'C04.557.580.600.610.595', 'C04.557.580.625.650.595'], ['E02.760.731.700', 'E04... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of periconceptional risk factor exposure and micronutrient supplementation on birth defects in Shaanxi Province in Western China. | OBJECTIVES: 1) To understand the current prevalence and main types of birth defects, 2) assess the periconceptional exposure of factors associated with birth defects in Shaanxi Province, and 3) provide scientific evidence for local governments to formulate services for the primary prevention of birth defects.METHODS: W... | ['Adult', 'China', 'Congenital Abnormalities', 'Delivery of Health Care', 'Dietary Supplements', 'Female', 'Folic Acid', 'Humans', 'Micronutrients', 'Pregnancy', 'Prevalence', 'Risk Factors', 'Surveys and Questionnaires'] | 23,300,928 | [['M01.060.116'], ['Z01.252.474.164'], ['C16.131'], ['N04.590.374', 'N05.300'], ['G07.203.300.456', 'J02.500.456'], ['D03.633.100.733.631.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.494', 'G07.203.300.681.500', 'J02.500.681.500'], ['G08.686.784.769'], ['E05.318.308.985.525.750', 'N01.224.935.5... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Cortisol level predicts myocardial infarction in patients with ischaemic chest pain. | Serum cortisol levels were studied in twenty patients with confirmed myocardial infarction and in twenty patients with severe chest pain admitted to the coronary care unit with suspected myocardial infarction but in whom a diagnosis of angina was subsequently made. Cortisol levels were significantly elevated in patient... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angina Pectoris', 'Biomarkers', 'Coronary Care Units', 'Diagnosis, Differential', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Myocardial Infarction'] | 2,793,263 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['D23.101'], ['N02.278.388.493.211'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Protein arginine methyltransferase 6 regulates embryonic stem cell identity. | Histone arginine methylation has emerged as an important histone modification involved in gene regulation. Protein arginine methyltransferase (PRMT) 4 and 5 have been shown to play essential roles in early embryonic development and in embryonic stem (ES) cells. Recently, it has been reported that PRMT6-mediated di-meth... | ['Animals', 'Biomarkers', 'Cell Differentiation', 'Cell Lineage', 'Cells, Cultured', 'Embryonic Stem Cells', 'Endoderm', 'Gene Expression Regulation, Enzymologic', 'Gene Knockdown Techniques', 'Histones', 'Homeodomain Proteins', 'Methylation', 'Mice', 'Nanog Homeobox Protein', 'Octamer Transcription Factor-3', 'Promote... | 22,455,726 | [['B01.050'], ['D23.101'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A11.251'], ['A11.872.700.250'], ['A16.504.407'], ['G05.308.320'], ['E05.393.335.500'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['D12.776.260.400'], ['G02.111.035.538', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation and implementation of in vivo transit dosimetry with an electronic portal imaging device]. | PURPOSE: In vivo dosimetry is now widely recommended to avoid major treatment error. Transit dosimetry using portal imagers allows fast and accurate in vivo dose verifications. Several teams have published clinical studies but no recommendation has been proposed to define tolerance levels and validation criteria. This ... | ['Algorithms', 'Humans', 'Neoplasms', 'Radiometry', 'Radiotherapy Dosage'] | 24,176,663 | [['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E05.799'], ['E02.815.639']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Actions of vitamins D2 and D3 and 25-OHD3 in anticonvulsant osteomalacia. | In 54 epileptic outpatients treated for at least one year with anticonvulsants the bone mineral content (B.M.C.), an estimate of total body calcium, and serum calcium were measured before and during treatment with three doses of cholecalciferol (vitamin D3; 200, 100, and 50 mu-g daily) and 25-hydroxycholecalciferol (25... | ['Anticonvulsants', 'Bone and Bones', 'Calcium', 'Cholecalciferol', 'Enzyme Induction', 'Epilepsy', 'Ergocalciferols', 'Humans', 'Hydroxycholecalciferols', 'Liver', 'Minerals', 'Osteomalacia'] | 165,857 | [['D27.505.954.427.080'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['G05.308.320.200'], ['C10.228.140.490'], ['D04.210.500.247.222.474', 'D04.210.500.247.808.412', 'D04.210... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impacts of air pollution wave on years of life lost: A crucial way to communicate the health risks of air pollution to the public. | Limited studies have explored the impacts of exposure to sustained high levels of air pollution (air pollution wave) on mortality. Given that the frequency, intensity and duration of air pollution wave has been increasing in highly polluted regions recently, understanding the impacts of air pollution wave is crucial. I... | ['Air Pollutants', 'Air Pollution', 'China', 'Environmental Exposure', 'Humans', 'Public Health', 'Risk'] | 29,421,406 | [['D27.888.284.101'], ['N06.850.460.100'], ['Z01.252.474.164'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Prenatal fluoxetine exposure induces life-long serotonin 5-HT₃ receptor-dependent cortical abnormalities and anxiety-like behaviour. | Selective serotonin reuptake inhibitors (SSRIs) are the first choice of drugs to treat depression and anxiety during pregnancy. However, there is evidence that in utero exposure to SSRIs leads to adverse effects in offspring. Here we show that in mice, the adverse effects of the widely used antidepressant and SSRI fluo... | ['Animals', 'Anxiety', 'Behavior, Animal', 'Cerebral Cortex', 'Female', 'Fluoxetine', 'Mice', 'Neurons', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Receptors, Serotonin, 5-HT3', 'Serotonin Uptake Inhibitors'] | 21,964,434 | [['B01.050'], ['F01.470.132'], ['F01.145.113'], ['A08.186.211.200.885.287.500'], ['D02.092.831.280'], ['B01.050.150.900.649.313.992.635.505.500'], ['A08.675', 'A11.671'], ['G08.686.784.769'], ['C13.703.824.500'], ['D12.776.157.530.400.400.100.700', 'D12.776.543.550.450.500.100.700', 'D12.776.543.585.400.500.100.700', '... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accurate quantification of 5 German cockroach (GCr) allergens in complex extracts using multiple reaction monitoring mass spectrometry (MRM MS). | BACKGROUND: German cockroach (GCr) allergen extracts are complex and heterogeneous products, and methods to better assess their potency and composition are needed for adequate studies of their safety and efficacy.OBJECTIVE AND METHODS: The objective of this study was to develop an assay based on liquid chromatography a... | ['Allergens', 'Animals', 'Blattellidae', 'Chromatography, Liquid', 'Complex Mixtures', 'Epitope Mapping', 'Humans', 'Mass Spectrometry', 'Peptide Library', 'Peptides', 'Reproducibility of Results'] | 28,756,650 | [['D23.050.063'], ['B01.050'], ['B01.050.500.131.617.140.100'], ['E05.196.181.400'], ['D20'], ['E05.478.274', 'E05.601.690.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D12.644.555', 'G02.111.570.060.620', 'G05.360.325.640'], ['D12.644'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A convenient approach to the synthesis of trinucleotide phosphoramidites--synthons for the generation of oligonucleotide/peptide libraries. | Trinucleotide phosphoramidites that correspond to the codons of all 20 amino acids were synthesized in high yield in 5g scale. Precursors of those amidites--trinucleotide phosphotriesters--have been prepared using the phosphotriester approach without protection of the 3'-hydroxyl function. The structures of trinucleoti... | ['Bacteriophages', 'Chromatography, High Pressure Liquid', 'Cloning, Molecular', 'Escherichia coli', 'Isomerism', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Oligodeoxyribonucleotides', 'Peptides'] | 8,871,554 | [['B04.123'], ['E05.196.181.400.300'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.570.685', 'G02.607.445'], ['E05.196.867.519'], ['E05.196.566'], ['D13.695.578.424.450'], ['D12.644']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comprehensive appraisal of 241Am in soils around Rocky Flats, Colorado. | Soils east of Rocky Flats Plant (RFETS) near Golden, Colorado, were contaminated with actinides because of accidental release of oils laden with plutonium isotopes. Consequently, these soils were contaminated by 241Am due to radioactive decay of 241Pu (t1/2 = 14.4 y). A spatial analysis of 241Am activity in soils east ... | ['Americium', 'Soil Pollutants, Radioactive'] | 8,698,577 | [['D01.268.271.100.050', 'D01.268.556.037', 'D01.496.749.305.100.050', 'D01.552.020.086', 'D01.552.544.037'], ['D20.693.756', 'D27.888.284.756.674']] | ['Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coexistent thyroid cancer and pregnancy. | OBJECTIVE: A study was performed to determine the appropriate time for the initiation of therapy for thyroid carcinoma first diagnosed during pregnancy.DATA SOURCES: Material on thyroid cancer cases was obtained from the New Mexico Tumor Registry, Albuquerque, a computerized population-based registry for the state of N... | ['Adolescent', 'Adult', 'Carcinoma, Papillary, Follicular', 'Female', 'Humans', 'Middle Aged', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Thyroid Neoplasms', 'Time Factors'] | 7,917,201 | [['M01.060.057'], ['M01.060.116'], ['C04.557.470.200.025.060.225', 'C04.557.470.200.025.085.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.784.769'], ['C04.850', 'C13.703.720'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The proportion of specific viral subpopulations in attenuated Arkansas Delmarva poultry industry infectious bronchitis vaccines influences vaccination outcome. | We investigated the significance of differing proportions of specific subpopulations among commercial Arkansas (Ark) Delmarva poultry industry (DPI) vaccines with regard to vaccination outcome. Two ArkDPI-derived vaccines that contain a higher proportion of viruses with S1 genes that become selected during replication ... | ['Animals', 'Antibodies, Viral', 'Chickens', 'Coronavirus Infections', 'Harderian Gland', 'Immunoglobulin G', 'Infectious bronchitis virus', 'Interferon-gamma', 'Membrane Glycoproteins', 'Molecular Sequence Data', 'Poultry Diseases', 'RNA, Messenger', 'Respiratory System', 'Reverse Transcriptase Polymerase Chain Reacti... | 23,397,834 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['C01.925.782.600.550.200'], ['A13.445'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Female urodynamics and lower urinary tract infection. | OBJECTIVES: To determine the incidence of unsuspected urinary tract infection (UTI) before cystometry, to evaluate reports of a greater tendency to abnormal cystometry in the presence of asymptomatic bacteriuria, and to determine the incidence of iatrogenic significant bacteriuria after cystometry.PATIENTS AND METHODS:... | ['Aged', 'Aged, 80 and over', 'Bacteriuria', 'Enterobacteriaceae', 'Enterobacteriaceae Infections', 'Female', 'Humans', 'Middle Aged', 'Prospective Studies', 'Risk Factors', 'Urinary Tract Infections', 'Urodynamics'] | 12,010,229 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.915.219', 'C12.777.892.219', 'C13.351.968.892.219'], ['B03.440.450.425', 'B03.660.250.150'], ['C01.150.252.400.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. | Sex determination in mammals is controlled by the presence or absence of the Y-linked gene SRY. In the developing male (XY) gonad, sex-determining region of the Y (SRY) protein acts to up-regulate expression of the related gene, SOX9, a transcriptional regulator that in turn initiates a downstream pathway of testis dev... | ['Animals', 'Disorders of Sex Development', 'Female', 'Gene Expression Regulation, Developmental', 'Humans', 'MAP Kinase Kinase Kinase 4', 'MAP Kinase Signaling System', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Ovary', 'Point Mutation', 'Sex Determination Processes', 'Sex-Determining Region Y Protein', 'Testis'] | 19,753,101 | [['B01.050'], ['C12.706.316', 'C13.351.875.253', 'C16.131.939.316', 'C19.391.119'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.559.400', 'D12.644.360.400.400', 'D12.776.476.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['B01.050.150.900.649.313.992.63... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of a polyvalent inactivated-virus vaccine in protecting mice from infection with clinical strains of group B coxsackieviruses. | A polyvalent vaccine developed from formalin-inactivated prototype strains of coxsackieviruses group B1-6 was tested for its ability to protect mice from acute infection with clinical strains. Adolescent male CD1 mice received an intraperitoneal injection, repeated once or twice at 8 day intervals, containing 0.3 ml pl... | ['Acute Disease', 'Animals', 'Antibodies, Viral', 'Coxsackievirus Infections', 'Enterovirus B, Human', 'Male', 'Mice', 'Species Specificity', 'Vaccines, Inactivated', 'Viral Vaccines'] | 7,747,099 | [['C23.550.291.125'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C01.925.782.687.359.213'], ['B04.820.578.750.284.182'], ['B01.050.150.900.649.313.992.635.505.500'], ['G16.824'], ['D20.215.894.830'], ['D20.215.894.899']] | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Successful treatment of mycotic thoracic aortic aneurysm by in situ graft replacement with omental wrapping. | Mycotic thoracic aortic aneurysm is a fatal disease. We report a case of a 67-year-old man presenting with contained rupture of a mycotic thoracic aortic aneurysm. Urgent in situ graft replacement was successfully performed with omental wrapping to prevent postoperative graft infection. | ['Aged', 'Aneurysm, Infected', 'Aortic Aneurysm, Thoracic', 'Aortic Rupture', 'Humans', 'Male', 'Omentum', 'Vascular Surgical Procedures'] | 16,519,134 | [['M01.060.116.100'], ['C01.069', 'C14.907.055.131'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['C14.907.055.185.125', 'C14.907.055.239.175', 'C14.907.109.139.175', 'C26.761.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.047.025.600.573'], ['E04.100.814']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparing the results of limited incision technique and standard longitudinal incision technique for carpal tunnel decompression by numerical grading system. | The carpal tunnel syndrome is the most common nerve entrapment syndrome. Many different methods have been described for treatment. We performed a novel method to release the carpal tunnel. Subsequently, we compared the surgery results of this novel limited incision technique and the standard longitudinal incision techn... | ['Adult', 'Aged', 'Carpal Tunnel Syndrome', 'Decompression, Surgical', 'Diagnosis, Computer-Assisted', 'Female', 'Follow-Up Studies', 'Hand Strength', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Preoperative Care', 'Pressure', 'Severity of Illness Index', 'Surgical Instruments', 'Transducers', 'You... | 19,263,354 | [['M01.060.116'], ['M01.060.116.100'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['E04.188'], ['E01.158', 'L01.313.500.750.100.158'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Facilitated AMPAR endocytosis causally contributes to the maternal sleep deprivation-induced impairments of synaptic plasticity and cognition in the offspring rats. | Maternal sleep deprivation (MSD) has been suggested to be associated with increased frequency of neurodevelopmental disorders in offspring in both humans and animal models. However, the underlying cellular and molecular mechanism is still unclear. We have recently reported that MSD at different stages of pregnancy impa... | ['Animals', 'Animals, Newborn', 'Disks Large Homolog 4 Protein', 'Endocytosis', 'Escape Reaction', 'Excitatory Postsynaptic Potentials', 'Female', 'Hippocampus', 'Male', 'Maze Learning', 'Neurodevelopmental Disorders', 'Neuronal Plasticity', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Rats, Sprague-Dawle... | 29,378,210 | [['B01.050'], ['B01.050.050.282'], ['D08.811.913.696.650.450.750', 'D12.644.360.265', 'D12.776.476.265', 'D12.776.543.219', 'D12.776.631.224'], ['G04.417'], ['F01.145.113.780.688', 'F01.145.367', 'F01.145.875.439.500.688', 'G07.568.500.590.688', 'G11.427.410.568.850.688'], ['G04.580.887.249', 'G07.265.675.887.249', 'G0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Influence of the endothelial nitric oxide synthase gene on conventional and ambulatory blood pressure: sib-pair analysis and haplotype study. | BACKGROUND: Nitric oxide is involved in the regulation of vascular basal tone and blood pressure. Polymorphisms of NOS3, the gene that codes for endothelial nitric oxide synthase, have been associated with essential hypertension.OBJECTIVE: To look for linkage and association of three di-allelic polymorphisms (Glu298Asp... | ['Adult', 'Angiotensin Amide', 'Belgium', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Female', 'Haplotypes', 'Humans', 'Linkage Disequilibrium', 'Male', 'Middle Aged', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type III', 'Twins, Dizygotic'] | 15,775,780 | [['M01.060.116'], ['D12.644.456.073.041.050', 'D23.469.050.050.050.050'], ['Z01.542.115'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.500'], ['M01.060.116.630'], ['D08.811.682.664.500.772'], ['D0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Neural mass models as a tool to investigate neural dynamics during seizures. | Epilepsy is one of the most common neurological disorders and is characterized by recurrent seizures. We use theoretical neuroscience tools to study brain dynamics during seizures. We derive and simulate a computational model of a network of hippocampal neuronal populations. Each population within the network is based ... | ['Brain', 'Electroencephalography', 'Epilepsy', 'Hippocampus', 'Humans', 'Models, Neurological', 'Seizures'] | 28,102,460 | [['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['C10.597.742', 'C23.888.592.742']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Flavonoid metabolites and susceptibility of rat lipoproteins to oxidation. | Flavonoids are ingested with vegetables and beverages and exert a beneficial effect on cardiovascular disease. Studies in animals in vitro and in humans ex vivo on the resistance of lipoproteins to oxidation are not consistent and the mechanisms by which flavonoids protect against atherosclerosis are a matter of debate... | ['Animal Feed', 'Animals', 'Arteriosclerosis', 'Catechin', 'Cholesterol, LDL', 'Flavonoids', 'Lipoproteins', 'Male', 'Oxidation-Reduction', 'Quercetin', 'Rats', 'Rats, Sprague-Dawley', 'Vitamin A', 'Wine', 'alpha-Tocopherol'] | 15,308,478 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['C14.907.137.126'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['D03.383.663.283.266.450... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The effect of dim light at night on cerebral hemodynamic oscillations during sleep: A near-infrared spectroscopy study. | Recent studies have reported that dim light at night (dLAN) is associated with risks of cardiovascular complications, such as hypertension and carotid atherosclerosis; however, little is known about the underlying mechanism. Here, we evaluated the effect of dLAN on the cerebrovascular system by analyzing cerebral hemod... | ['Adult', 'Cerebrum', 'Electroencephalography', 'Hemodynamics', 'Humans', 'Light', 'Male', 'Neurovascular Coupling', 'Polysomnography', 'Sleep, REM', 'Sleep, Slow-Wave', 'Spectroscopy, Near-Infrared', 'Young Adult'] | 29,064,336 | [['M01.060.116'], ['A08.186.211.200.885.287'], ['E01.370.376.300', 'E01.370.405.245'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G09.330.100.159.500'], ['E01.370.520.625'], ['F02.830.855.796.671', 'G11.561.803.754.67... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence and correlates of community re-entry challenges faced by HIV-infected male prisoners in Malaysia. | HIV-infected prisoners face an inordinate number of community re-entry challenges. In 2007, 102 HIV-infected prisoners in Malaysia were surveyed anonymously within six months prior to release to assess the prevalence and correlates of community re-entry challenges. Staying out of prison (60.8%), remaining off drugs (39... | ['Adult', 'HIV Infections', 'Humans', 'Logistic Models', 'Malaysia', 'Male', 'Prevalence', 'Prisoners'] | 20,606,222 | [['M01.060.116'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Short-term clinical outcomes after HLA 1-locus mismatched uPBSCT are similar to that after HLA-matched uPBSCT and uBMT. | In Japan, use of unrelated peripheral blood stem cell transplantation (uPBSCT) from HLA-mismatched unrelated donors has recently been approved. We compared outcomes between HLA-matched and 1-locus mismatched uPBSCT, as well as the impact of HLA disparity in uPBSCT and in unrelated bone marrow transplantation (uBMT). In... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Alleles', 'Antilymphocyte Serum', 'Bone Marrow Transplantation', 'Child', 'Child, Preschool', 'Feasibility Studies', 'Female', 'Graft vs Host Disease', 'HLA Antigens', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Peripheral Blood Stem Cell Transplantation', 'Retrospectiv... | 30,877,606 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.060.406'], ... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Eighteen-month evaluation of the effects of a 0.4% stannous fluoride gel on gingivitis in orthodontic patients. | The purpose of this study was to determine whether conventional toothbrushing and twice daily use of a brush-on 0.4% stannous fluoride (SnF2) gel containing more than 90% available Sn2+ would be more effective for controlling plaque accumulation and gingivitis in the presence of orthodontic appliances than conventional... | ['Adolescent', 'Analysis of Variance', 'Child', 'Dental Plaque', 'Dental Plaque Index', 'Gels', 'Gingivitis', 'Humans', 'Longitudinal Studies', 'Male', 'Observer Variation', 'Orthodontic Appliances', 'Patient Compliance', 'Periodontal Index', 'Single-Blind Method', 'Tin Fluorides', 'Toothbrushing'] | 8,291,491 | [['M01.060.057'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['D20.280.320', 'D26.255.165.320'], ['C01.408', 'C07.465.714... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Physical self-maintenance, mental status, and personality in institutionalized elderly adults. | Administered the projective Hand Test (HT) to 52 institutionalized elderly adults in order to establish its validity in measuring individual differences in relationships between mental status and physical self-maintenance ability. Results suggested substantial covariance among level of self-care, organic dysfunction, a... | ['Aged', 'Dementia', 'Female', 'Humans', 'Institutionalization', 'Male', 'Personality Assessment', 'Psychometrics', 'Self Care'] | 6,874,986 | [['M01.060.116.100'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.415', 'N02.421.585.415'], ['F04.513'], ['F04.711.780'], ['E02.900', 'I03.050.563', 'N02.421.784.680']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[R-(Z)]-4-amino-3-chloro-2-pentenedioic acid, a new antibiotic. Fermentation, isolation and characterization. | A new unsaturated glutamic acid analog, 4-amino-3-chloro-2-pentenedioic acid ( ACPA ) was isolated from a fermentation broth produced by a strain of Streptomyces. ACPA has a very narrow antibacterial spectrum, which is virtually limited to Micrococcus luteus. | ['Anti-Bacterial Agents', 'Bacillus subtilis', 'Chemical Phenomena', 'Chemistry', 'Fermentation', 'Glutamates', 'Magnetic Resonance Spectroscopy', 'Microbial Sensitivity Tests', 'Micrococcus', 'Streptomyces', 'X-Ray Diffraction'] | 6,427,163 | [['D27.505.954.122.085'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['G02'], ['H01.181'], ['G02.111.158.249', 'G03.191.249'], ['D12.125.067.625', 'D12.125.119.409'], ['E05.196.867.519'], ['E01.370.225.875.595', 'E... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative genomic analysis of fungal genomes reveals intron-rich ancestors. | BACKGROUND: Eukaryotic protein-coding genes are interrupted by spliceosomal introns, which are removed from transcripts before protein translation. Many facets of spliceosomal intron evolution, including age, mechanisms of origins, the role of natural selection, and the causes of the vast differences in intron number b... | ['Bayes Theorem', 'Computational Biology', 'Computer Simulation', 'Evolution, Molecular', 'Genome, Fungal', 'Genomics', 'Introns', 'Phylogeny', 'Selection, Genetic', 'Spliceosomes'] | 17,949,488 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.358.365'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['G05.697', 'G16.075.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Endogenous cortisol production in response to knee arthroscopy and total knee arthroplasty. | BACKGROUND: There is controversy about whether patients who take exogenous glucocorticoids, such as prednisone, require supplemental (exogenous) glucocorticoids in order to meet the physiological demands of surgery. In this study, we sought to define the magnitude of the surgical stress response in normal patients unde... | ['Arthroplasty, Replacement, Knee', 'Arthroscopy', 'Cohort Studies', 'Humans', 'Hydrocortisone', 'Knee Joint', 'Prospective Studies', 'Stress, Physiological'] | 14,630,847 | [['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Factors associated with co-morbid irritable bowel syndrome and chronic fatigue-like symptoms in functional dyspepsia. | BACKGROUND: It is unclear which factors explain the high co-morbidity between functional dyspepsia (FD) and other functional somatic syndromes. The aim of this study is to investigate the association between gastric sensorimotor function, psychosocial factors and 'somatization' on the one hand, and co-morbid irritable ... | ['Adult', 'Comorbidity', 'Dyspepsia', 'Fatigue Syndrome, Chronic', 'Female', 'Humans', 'Irritable Bowel Syndrome', 'Middle Aged', 'Risk Factors', 'Stomach', 'Surveys and Questionnaires'] | 21,255,194 | [['M01.060.116'], ['N05.715.350.225', 'N06.850.490.687'], ['C23.888.821.236'], ['C01.925.330', 'C05.651.310', 'C10.228.440.600', 'C10.668.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.158.272.608'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges. | AIM: A number of K(+) channels are regulated by small, fast changes in cell volume. The mechanisms underlying cell volume sensitivity are not known, but one possible mechanism could be purinergic signalling. Volume activated ATP release could trigger signalling pathways that subsequently lead to ion channel stimulation... | ['Adenosine', 'Adenosine Triphosphate', 'Animals', 'Aquaporin 1', 'Cell Size', 'Genes, Reporter', 'Humans', 'Ion Channel Gating', 'KCNQ1 Potassium Channel', 'Mechanotransduction, Cellular', 'Membrane Potentials', 'Oocytes', 'Osmotic Pressure', 'Patch-Clamp Techniques', 'Potassium Channels, Voltage-Gated', 'Purinergic A... | 22,805,606 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D12.776.157.530.400.500.040.374', 'D12.776.543.550.450.730.040.374', 'D12.776.543.585.400.730.040.436'], ['G04.325'], ['G05.360.340.024.340.435'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human SY5Y neuroblastoma cell interactions with laminin isoforms: neurite outgrowth on laminin-5 is mediated by integrin alpha 3 beta 1. | Laminin (Ln) isoforms may play important roles in neuronal development, particularly axon guidance, but neural receptors mediating interactions with Ln are not entirely understood. In this paper, we have compared the adhesive and process outgrowth activities of a human neuroblastoma cell line SY5Y on various laminin is... | ['Animals', 'Antibodies, Monoclonal', 'Cell Adhesion', 'Cell Adhesion Molecules', 'Cell Extracts', 'Extracellular Matrix', 'Humans', 'Integrin alpha3beta1', 'Integrins', 'Laminin', 'Mice', 'Molecular Weight', 'Neurites', 'Neuroblastoma', 'Placenta', 'Receptors, Laminin', 'Tumor Cells, Cultured'] | 8,807,189 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.022'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D20.777.162'], ['A11.284.295.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.685.300', 'D12.776.543.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two forms of spatial imagery: neuroimaging evidence. | Spatial imagery may be useful in such tasks as interpreting graphs and solving geometry problems, and even in performing surgery. This study provides evidence that spatial imagery is not a single faculty; rather, visualizing spatial location and mentally transforming location rely on distinct neural networks. Using 3-T... | ['Adolescent', 'Adult', 'Brain', 'Brain Mapping', 'Cues', 'Female', 'Humans', 'Imagination', 'Magnetic Resonance Imaging', 'Male', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Space Perception', 'Students', 'Task Performance and Analysis', 'Young Adult'] | 19,765,238 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.188.634'], ['E01.370.350.825.500'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['F02.463.59... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
No evidence of increased risk of malignancies in patients with diabetes treated with insulin detemir: a meta-analysis. | AIMS/HYPOTHESIS: Recent epidemiological studies suggest that treatment with insulin glargine (A21Gly,B31Arg,B32Arg human insulin) may promote cancer growth. The present meta-analysis was performed to assess the risk of cancer during treatment with insulin detemir (B29Lys(epsilon-tetradecanoyl),desB30 human insulin), an... | ['Adult', 'Aged', 'Body Mass Index', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Hypoglycemic Agents', 'Incidence', 'Insulin', 'Insulin Detemir', 'Insulin, Isophane', 'Insulin, Long-Acting', 'Male', 'Middle Aged', 'Neoplasms', 'Randomized Controlled Trials as Topic'] | 19,838,665 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['E05.318.308.985.525.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Topical Silymarin Administration for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial. | Hand-foot syndrome (HFS) is a frequent dose-limiting adverse reaction of capecitabine in patient with gastrointestinal cancers. Silymarin is a polyphenolic flavonoid extracted from the Silybum marianum that exhibits strong antioxidant and antiinflammatory activities. In this study, we evaluated silymarin efficacy in pr... | ['Administration, Cutaneous', 'Aged', 'Antimetabolites, Antineoplastic', 'Capecitabine', 'Female', 'Hand-Foot Syndrome', 'Humans', 'Male', 'Middle Aged', 'Milk Thistle', 'Phytotherapy', 'Silymarin'] | 28,635,153 | [['E02.319.267.120.060'], ['M01.060.116.100'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['C17.800.174.600.587', 'C25.100.468.380.587'], ['B01.050.150.900.649.313.988.400.112.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cervical Myelopathy without Symptoms in the Upper Extremities: Incidence and Presenting Characteristics. | BACKGROUND: Common signs and symptoms of cervical myelopathy (CM) predominantly manifest in the upper extremities and include hand numbness, hand clumsiness, and distal upper extremity weakness. CM manifesting without symptoms in the upper extremities is rare. This study aimed to better understand the incidence and cha... | ['Adult', 'Aged', 'Cervical Vertebrae', 'Decompression, Surgical', 'Female', 'Humans', 'Hypesthesia', 'Incidence', 'Intervertebral Disc Degeneration', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Mobility Limitation', 'Muscle Weakness', 'Retrospective Studies', 'Spinal Cord Compression', 'Spinal Cord Diseases'... | 31,513,953 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.232.834.151'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.751.791.500', 'C23.888.592.763.770.500'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C05.116.900.153'], ['E01.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The evaluation stage of the Hoeven Outcome Monitor (HOM): Towards an evidence based groundwork in forensic mental health. | This study examined if a macro-, meso-, and micro outcome measurement instrument that constitutes the evaluation stage of a Dutch forensic psychiatric outcome monitor, the Hoeven Outcome Monitor (HOM), can provide a first step towards a more evidence based groundwork in forensic mental health. General, serious, very se... | ['Adult', 'Evidence-Based Medicine', 'Female', 'Forensic Psychiatry', 'Humans', 'Male', 'Mental Disorders', 'Mental Health', 'Netherlands', 'Patient Discharge', 'Recidivism'] | 28,256,255 | [['M01.060.116'], ['H02.249.750', 'H02.403.200.400'], ['F04.096.544.335', 'H02.403.690.208', 'I01.198.780.937.469', 'I01.880.604.583.310', 'N03.706.535.351'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F02.418', 'N01.400.500'], ['Z01.542.651'], ['E02.760.169.125', 'E02.760.400.610', 'N02.421.585.169.12... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Replication of porcine parvovirus in peripheral blood lymphocytes, monocytes, and peritoneal macrophages. | Porcine peripheral blood lymphocytes (PBL), peripheral blood monocytes, and peritoneal macrophages were examined for their ability to support porcine parvovirus (PPV) replication. The cell cultures were infected with the NADL-2 strain of PPV at 0.1 multiplicity of infection. PBL cultures were stimulated with the follow... | ['Animals', 'Antigens, Viral', 'Concanavalin A', 'Cytoplasm', 'Lymphocyte Activation', 'Lymphocytes', 'Macrophages', 'Monocytes', 'Parvoviridae', 'Phytohemagglutinins', 'Pokeweed Mitogens', 'Swine'] | 574,124 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Community-based validation of the McCormick Toy Test. | The aim of the present study was to investigate the validity of a community-based hearing test to detect conductive hearing loss in 3-year-old children. Sixty-five children had their hearing tested using standard audiological tests at the same time as they underwent their 3-year-old health checks. The checks were perfo... | ['Acoustic Impedance Tests', 'Audiometry', 'Child, Preschool', 'Community Health Services', 'Female', 'Hearing Loss, Conductive', 'Hearing Tests', 'Humans', 'Male', 'Mass Screening', 'Otitis Media with Effusion', 'Otoscopes', 'Play and Playthings', 'Predictive Value of Tests', 'Reproducibility of Results', 'Severity of... | 11,081,752 | [['E01.370.382.375.050'], ['E01.370.382.375.060'], ['M01.060.406.448'], ['N02.421.143'], ['C09.218.458.341.562', 'C10.597.751.418.341.562', 'C23.888.592.763.393.341.562'], ['E01.370.382.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of temperature and humidity on the development of eggs of Toxocara canis under laboratory conditions. | The influence of temperature and humidity on the survival and development of Toxocara canis eggs in an in vitro model system was investigated. Two soil samples were inoculated with T. canis eggs and maintained at 3% and 50% humidity and temperatures of 19-24 degrees C. Nine soil samples were inoculated with T. canis eg... | ['Animals', 'Eggs', 'Environment', 'Humidity', 'Parasitology', 'Soil', 'Temperature', 'Toxocara canis'] | 16,336,716 | [['B01.050'], ['G07.203.300.470', 'J02.500.470'], ['G16.500.275', 'N06.230'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['H01.158.273.688'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Homicides among women in the different Brazilian regions in the last 35 years: an analysis of age-period-birth cohort effects. | The aim of this study is to estimate the effects of age-period-birth cohort (APC) on female homicides. This is an ecological study which analyzed the violence-related death records of women aged 10 years and older, in the Brazilian geographic regions, between 1980 and 2014. Data on mortality were extracted from the Mor... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Brazil', 'Child', 'Cohort Effect', 'Female', 'Health Information Systems', 'Homicide', 'Humans', 'Middle Aged', 'Mortality', 'Violence', 'Young Adult'] | 28,954,146 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.107.757.176'], ['M01.060.406'], ['N05.715.350.350.225', 'N06.850.490.734.500'], ['L01.313.500.750.300.361'], ['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'],... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Delayed weaning and denial of solid food nibbling upon pancreatic acinar cell responsiveness to urecholine in neonatal rats. | Pancreatic response to urecholine was studied in rats which were fed maternal milk only until they reached 27 days of age. A group of pups which remained all the time with their mother were weaned at 21 days; over that nursing period, their pancreatic amylase concentration increased gradually, lipase started to decreas... | ['Amylases', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Animals, Newborn', 'Bethanechol Compounds', 'Chymotrypsin', 'Lipase', 'Milk', 'Pancreas', 'Pancreatic Juice', 'Rats', 'Weaning'] | 729,949 | [['D08.811.277.450.066'], ['G07.203.650.161'], ['B01.050'], ['B01.050.050.282'], ['D02.092.877.883.088', 'D02.241.081.251.133', 'D02.675.276.148'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['D08.811.277.352.100.400'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Relative handgrip strength, nutritional status and abdominal obesity in Chilean adolescents. | Handgrip strength (HGS) is a well-established indicator of muscle strength and can help to identify risk of sarcopenic obesity in children. This study explores the relationship between adiposity and muscular strength in healthy Chilean adolescents. Adolescents (n = 491) aged 10-17 were selected from five schools in San... | ['Adiposity', 'Adolescent', 'Body Mass Index', 'Body Weight', 'Child', 'Chile', 'Cross-Sectional Studies', 'Female', 'Hand Strength', 'Humans', 'Male', 'Nutrition Assessment', 'Nutritional Status', 'Obesity, Abdominal', 'Overweight', 'Pediatric Obesity', 'Prevalence', 'Risk Factors', 'Waist Circumference'] | 32,520,942 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Isolation and biological characterization of a novel type of pulmonary mesenchymal stem cells derived from Wuzhishan miniature pig embryo. | Pulmonary mesenchymal stem cells (PMSCs) have great potential in lung tissue engineering and represent attractive candidates for disease treatment in human and veterinary research. However, a reliable method for isolation and localization of porcine PMSCs in situ is still uncertain. In this study, we successfully isola... | ['Adipocytes', 'Animals', 'Cell Differentiation', 'Cell Proliferation', 'Cell Separation', 'Chondrocytes', 'Fibroblasts', 'Fluorescent Antibody Technique', 'Lung', 'Mesenchymal Stem Cells', 'Pluripotent Stem Cells', 'Swine', 'Swine, Miniature', 'Tissue Engineering'] | 27,425,208 | [['A11.329.114'], ['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.329.171'], ['A11.329.228'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A04.... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
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