Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Inhibition of suicidal erythrocyte death by xanthohumol. | Xanthohumol is a proapoptotic hop-derived beer component with anticancer and antimicrobial activities. Similar to nucleated cells, erythrocytes may undergo suicidal cell death or eryptosis, which is triggered by oxidative stress (tert-butylhydroperoxide, TBOOH) or energy depletion (removal of glucose). The triggers inc... | ['Calcium', 'Cell Death', 'Down-Regulation', 'Erythrocytes', 'Flavonoids', 'Humans', 'Propiophenones'] | 19,642,672 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.146'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.522.818']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cross-cultural adaptation and validation of the Chinese abbreviated profile of hearing aid benefit. | OBJECTIVE: The objective of the study was to investigate the cross-cultural validity and reliability of the Chinese version of the Abbreviated Profile of the Hearing Aid Benefit questionnaire (APHAB-CH).DESIGN: A convenience sampling method was used to identify and recruit subjects. The subjects completed a history for... | ['Asian Continental Ancestry Group', 'China', 'Factor Analysis, Statistical', 'Hearing Aids', 'Humans', 'Outcome Assessment, Health Care', 'Reproducibility of Results', 'Surveys and Questionnaires'] | 21,271,802 | [['M01.686.508.200'], ['Z01.252.474.164'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['E07.305.906.500', 'E07.814.458'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Influence of sprint acceleration stance kinetics on velocity and step kinematics in field sport athletes. | The interaction between step kinematics and stance kinetics determines sprint velocity. However, the influence that stance kinetics has on effective acceleration in field sport athletes requires clarification. About 25 men (age = 22.4 ± 3.2 years; mass = 82.8 ± 7.2 kg; height = 1.81 ± 0.07 m) completed twelve 10-m spri... | ['Athletic Performance', 'Biomechanical Phenomena', 'Humans', 'Male', 'Running', 'Young Adult'] | 23,222,091 | [['I03.450.642.845.054'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['M01.060.116.815']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Cloning of cDNA to rat mammary-gland fatty acid synthase mRNA. Evidence for the expression of two mRNA species during lactation. | A cDNA library was constructed in the expression vector lambda gt11, by synthesizing cDNA from size-selected poly(A) RNA from lactating rat mammary gland, using random hexanucleotide primers. Using this library we identified two recombinants which, on addition of a lac z inducer, produced proteins recognized by affinit... | ['Animals', 'Antibodies', 'Cloning, Molecular', 'DNA, Circular', 'Electrophoresis, Agar Gel', 'Fatty Acid Synthases', 'Female', 'Lactation', 'Mammary Glands, Animal', 'Nucleic Acid Hybridization', 'Pregnancy', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains'] | 3,342,031 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.393.220'], ['D13.444.308.283', 'G02.111.570.820.486.212', 'G05.360.580.156'], ['E05.196.401.153', 'E05.301.300.100'], ['D08.811.277.352.897.387', 'D08.811.520.241.300.287', 'D08.811.682.047.820.196.500', 'D08.811.913.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A newly revised classification of the protozoa. | The subkingdom Protozoa now inclues over 65,000 named species, of which over half are fossil and approximately 10,000 are parasitic. Among living species, this includes approximately 250 parasitic and 11,300 free-living sarcodines (of which approximately 4,600 are foraminiferids); approximately 1,8000 parasitic and 5,1... | ['Animals', 'Bibliographies as Topic', 'Eukaryota', 'Terminology as Topic'] | 6,989,987 | [['B01.050'], ['L01.178.682.099', 'L01.453.183'], ['B01'], ['L01.559.598.400']] | ['Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Basal cell carcinoma with neuroendocrine differentiation arising in a scar: A case report. | Basal cell carcinoma (BCC), the most common cutaneous malignant tumor, may display neuroendocrine differentiation in very rare instances. We here describe a case of a BCC with neuroendocrine differentiation that arose in a scar resulting from a trauma 75 years earlier. Neuroendocrine differentiation was proven by immun... | ['Aged', 'Carcinoma, Basal Cell', 'Cicatrix', 'Female', 'Humans', 'Skin Neoplasms'] | 19,951,622 | [['M01.060.116.100'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.805', 'C17.800.882']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dynamics of culling for Jersey, Holstein, and Jersey ? Holstein crossbred cows in large multibreed dairy herds. | The objective of this observational study was to describe and compare the dynamics of reason-specific culling risk for the genetic groups Jerseys (JE), Holsteins (HO), and Jersey ? Holstein crossbreds (JH), considering parity, stage of lactation, and milk yield, among other variables, in large multibreed dairy herds in... | ['Animal Husbandry', 'Animals', 'Cattle', 'Dairying', 'Female', 'Lactation', 'Longevity', 'Pregnancy', 'Texas'] | 24,612,810 | [['J01.040.090'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['G08.686.523', 'G08.686.702.500'], ['G07.345.124.519', 'G07.540'], ['G08.686.784.769'], ['Z01.107.567.875.760.750']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Trends in neonatal and infant mortality in five continents. | Trends in the mortality rates for the periods 0-6, 7-27, 28-365 and 0-365 days after birth have been analysed in 48 European, American, African, Asian and Australian countries included in the World Health Organization (WHO) mortality database. From the late 1960s to the early 1990s infant mortality rates declined stead... | ['Birth Rate', 'Cause of Death', 'Cross-Cultural Comparison', 'Cross-Sectional Studies', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Male'] | 9,297,761 | [['E05.318.308.985.775.500', 'N01.224.935.849.500', 'N06.850.505.400.975.775.500', 'N06.850.520.308.985.775.500'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['E05.318.372.500.875', 'N05.715.360.330.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[The parental origin of the extra chromosome 21 in Down's syndrome]. | The parental origin of the extra chromosome 21 and the meiotic failure involved were traced in 100 patients with Down syndrome and the relation with parental age was studied. In 20% of the cases the extra chromosome appeared to be of paternal origin (half of which caused by a nondisjunction at meiosis I, the remaining ... | ['Adult', 'Age Factors', 'Child', 'Chromosome Aberrations', 'Chromosomes, Human, 21-22 and Y', 'Down Syndrome', 'Female', 'Humans', 'Male', 'Maternal Age', 'Meiosis', 'Middle Aged', 'Parents', 'Pregnancy', 'Risk', 'Translocation, Genetic'] | 6,230,758 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.505', 'G05.360.162.520.300.505'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.560', 'N05.7... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter. | Leukoencephalopathy with vanishing white matter is a recently defined autosomal recessive disorder. The course is chronic progressive with additional episodes of rapid deterioration, provoked by fever and minor head trauma. A previous study showed that mutations in the genes encoding the epsilon- or the beta-subunit of... | ['Brain Diseases', 'DNA Mutational Analysis', 'Eukaryotic Initiation Factor-2B', 'Humans', 'Magnetic Resonance Imaging', 'Mutation', 'Nerve Fibers, Myelinated', 'Phenotype', 'Protein Biosynthesis'] | 11,835,386 | [['C10.228.140'], ['E05.393.760.700.300'], ['D12.644.360.325.300.050', 'D12.776.476.325.300.050', 'D12.776.835.725.868.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['G05.365.590'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.514'], ['G05.695'], ['G02.111.660.871', 'G03.734.871', ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacodynamic modeling of verapamil effects under steady-state and nonsteady-state conditions. | Pharmacodynamic models relating the plasma concentration (Cp) of verapamil to the drug's effect (E) on the P-R interval were investigated after single dose infusions of (0.15-0.22 mg/kg) verapamil in 22 normal subjects. Model predictions of the steady-state Cp-E relationship were then compared to results from actual st... | ['Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Biological', 'Regression Analysis', 'Verapamil'] | 2,600,802 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.395'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['D02.092.471.683.953']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Genetic polymorphism of NFKB1 gene in Chinese Han of Chengdu and Thai populations]. | OBJECTIVE: To investigate the single nucleotide polymorphisms (rs3774963 C>G and rs11722146 A>G) of NFKB1 gene between the Chinese Han of Chengdu and Thai populations, and simultaneously to compare distributions of genotype and allelic frequencies of NFKB1 among different ethnic groups from the International Haplotype ... | ['Base Sequence', 'China', 'Female', 'Gene Frequency', 'Genotype', 'Humans', 'Male', 'NF-kappa B p50 Subunit', 'Polymorphism, Single Nucleotide', 'Thailand'] | 19,627,002 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.252.474.164'], ['G05.330'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.260.600.124', 'D12.776.660.600.124', 'D12.776.930.600.124'], ['G05.365.795.598'], ['Z01.252.145.841']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Exploring the technical aspects of "fit" in qualitative research. | The concept of fit and processes of fitting have been largely ignored in qualitative inquiry. In this article, the authors address the technical significance of fit as an analytic process for both data and concepts in the process of theory construction. The ramifications of violating processes of fit and examples of mi... | ['Evaluation Studies as Topic', 'Health Services Research', 'Humans', 'Models, Theoretical', 'Research Design'] | 11,710,081 | [['E05.337', 'N05.715.360.335'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E05.581.500', 'H01.770.644.728']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Responses of tooth eruption and alveolar bone subject to somatic growth retardation in the rat. | The morphogenesis and regression of the osteodental fissure formed by alveolar bone in the maxillary and mandibular regions has been investigated in relation to eruption of the dentition during and following a period of somatic retardation stemming from nutritional suppression. Fissural formation occurred above the fir... | ['Alveolar Process', 'Animals', 'Female', 'Incisor', 'Male', 'Mandible', 'Maxillofacial Development', 'Molar', 'Morphogenesis', 'Nutrition Disorders', 'Rats', 'Time Factors', 'Tooth Eruption'] | 7,257,885 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['B01.050'], ['A14.549.167.860.425'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['G07.345.500.325.377.625.050.500.478', 'G11.427.578.050.500.478'], ['A14.549.167.860.525'], ['G07.345.500'], ['C18.654'], ['B01.050.150.900.649.313.992.635.505.7... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impaired phagocytic activity of neutrophils in patients receiving haemodialysis: the critical role of iron overload. | The metabolic burst (as measured by the spontaneous and stimulated nitroblue tetrazolium tests), the phagocytosis of heat inactivated bakers' yeast and of Staphylococcus aureus, the killing of Staph aureus, and the myeloperoxidase activity of polymorphonuclear neutrophils were studied in 11 patients receiving maintenan... | ['Adult', 'Aged', 'Deferoxamine', 'Ferritins', 'Humans', 'Iron', 'Middle Aged', 'Neutrophils', 'Peroxidase', 'Phagocytosis', 'Renal Dialysis'] | 2,992,675 | [['M01.060.116'], ['M01.060.116.100'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['M01.060.116.630'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
DNA damage in metabolic syndrome and its association with antioxidative and oxidative measurements. | The purpose of this study was to assess DNA damage levels in subjects with metabolic syndrome (MetS). Sixty-five subjects with MetS and 65 controls were enrolled in this study. Levels of DNA damage, total antioxidant capacity (TAC), total peroxide and oxidative stress index (OSI) were measured. We found that DNA damage... | ['Adult', 'Aged', 'Antioxidants', 'Case-Control Studies', 'Comet Assay', 'DNA Damage', 'Female', 'Humans', 'Lymphocytes', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Oxidants', 'Oxidation-Reduction', 'Oxidative Stress', 'Peroxides'] | 16,981,963 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src. | Interleukin 1 (IL-1) has been implicated in the reorganization of the actin cytoskeleton. An expression vector encoding a PKB/Akt pleckstrin-homology domain fused to a fluorescent protein was used to detect phosphoinositide 3-kinase (PI 3-kinase) products. It was observed that PI 3-kinase was activated either by treatm... | ['Actins', 'Amino Acid Motifs', 'Cell Line', 'Cytoskeleton', 'Humans', 'Interleukin-1', 'Models, Biological', 'NF-kappa B', 'Phosphatidylinositol 3-Kinases', 'Protein Structure, Tertiary', 'Proto-Oncogene Proteins p21(ras)', 'Proto-Oncogene Proteins pp60(c-src)', 'Pseudopodia', 'Signal Transduction', 'TNF Receptor-Asso... | 16,569,657 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['A11.251.210'], ['A11.284.430.214.190.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.77... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Value of transthoracic echocardiography for the detection of high-grade coronary artery stenosis: prospective evaluation in 50 consecutive patients scheduled for coronary angiography. | We prospectively evaluated the feasibility of direct, transthoracic evaluation of coronary arteries to diagnose flow-limiting lesions. Second harmonic mode in B-mode and fundamental mode for Doppler examinations was used. A stenosis was diagnosed when maximal flow velocity at least doubled in comparison with that of th... | ['Adult', 'Aged', 'Angioplasty, Balloon, Coronary', 'Blood Flow Velocity', 'Coronary Angiography', 'Coronary Disease', 'Echocardiography, Doppler, Color', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Treatment Outcome'] | 11,119,277 | [['M01.060.116'], ['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.350.130.625', 'E01.370.35... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The antihyperalgesic effect of venlafaxine in diabetic rats does not involve the opioid system. | Venlafaxine (VFX) is a structurally novel antidepressant that inhibits reuptake of serotonin and norepinephrine but, unlike tricyclic antidepressants, has few side effects. The present work studies the antihyperalgesic effect of repeated administrations of VFX (five successive injections of 2.5, 5 or 10 mg/kg, s.c., ev... | ['Analgesics', 'Animals', 'Cyclohexanols', 'Diabetes Complications', 'Dose-Response Relationship, Drug', 'Hyperalgesia', 'Male', 'Naloxone', 'Narcotic Antagonists', 'Pain Threshold', 'Pressure', 'Rats', 'Rats, Sprague-Dawley', 'Venlafaxine Hydrochloride', 'Vocalization, Animal'] | 12,727,329 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['C19.246.099'], ['G07.690.773.875', 'G07.690.936.500'], ['C10.597.751.791.400', 'C23.888.592.763.770.400'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimizing the arterialized venous flap. | BACKGROUND: Outcome of arterialized venous flaps is quite varied. The authors' initial experiments showed that a good vascular bed contributes significantly to survival of the flap. In continuation of these experiments, this study aimed to understand the influence of architectural variations on flap outcome.METHODS: Fa... | ['Angiography', 'Animals', 'Arteries', 'Arteriovenous Shunt, Surgical', 'Ear, External', 'Microcirculation', 'Models, Animal', 'Neovascularization, Physiologic', 'Rabbits', 'Regional Blood Flow', 'Surgical Flaps', 'Veins'] | 19,050,520 | [['E01.370.350.700.060', 'E01.370.370.050'], ['B01.050'], ['A07.015.114'], ['E04.035.087', 'E04.100.814.868.249'], ['A09.246.272'], ['G09.330.100.645'], ['E05.598'], ['G09.330.630'], ['B01.050.150.900.649.313.968.700'], ['G09.330.100.780'], ['A10.850.710', 'E07.862.710'], ['A07.015.908']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of CNC prototype for the characterization of the nanoparticle release during physical manipulation of nanocomposites. | This work focuses on the release of nanoparticles from commercially used nanocomposites during machining operations. A reliable and repeatable method was developed to assess the intentionally exposure to nanoparticles, in particular during drilling. This article presents the description and validation of results obtain... | ['Air Pollutants', 'Dust', 'Environmental Exposure', 'Environmental Monitoring', 'Nanocomposites', 'Nanoparticles'] | 26,889,574 | [['D27.888.284.101'], ['D20.633.222'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['J01.637.512.150'], ['J01.637.512.600']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Whole-Body and Local Muscle Vibration Immediately Improve Quadriceps Function in Individuals With Anterior Cruciate Ligament Reconstruction. | OBJECTIVE: To determine the immediate effects of a single session of whole-body vibration (WBV) and local muscle vibration (LMV) on quadriceps function in individuals with anterior cruciate ligament reconstruction (ACLR).DESIGN: Singe-blind, randomized crossover trial.SETTING: Research laboratory.PARTICIPANTS: Populati... | ['Anterior Cruciate Ligament Reconstruction', 'Cross-Over Studies', 'Evoked Potentials, Motor', 'Female', 'Humans', 'Isometric Contraction', 'Knee Joint', 'Male', 'Muscle Strength', 'Physical Therapy Modalities', 'Quadriceps Muscle', 'Single-Blind Method', 'Torque', 'Vibration', 'Young Adult'] | 26,869,286 | [['E04.555.110.026', 'E04.680.101.026'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A02.835.583.475'], ['E01.370.600.425', 'G11.427.560'], ['E02.779', 'E02.831.535'], ['A02.633... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytogenotoxicity of selected organophosphate insecticides on HaCaT keratinocytes and NL-20 human bronchial cells. | Organophosphate insecticides (OI) are widely used. To humans the main routes of exposure are skin and inhalation. For this, keratinocytes (HaCaT) and bronchial cells (NL-20) were used as cell culture models to evaluate the effects of OI. The aim of this study was to evaluate the effect of four OI on HaCaT and NL-20 cel... | ['Bronchi', 'Cell Death', 'Cell Line', 'Cell Survival', 'Comet Assay', 'DNA Damage', 'Humans', 'Insecticides', 'Keratinocytes', 'Mutagens', 'Organophosphorus Compounds'] | 26,688,254 | [['A04.411.125'], ['G04.146'], ['A11.251.210'], ['G04.346'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.031.700.491', 'D27.888.723.491'], ['A11.409.500', 'A11.436.397'], ['D27.888.569.468'], ['D02.705']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mason type II radial head fractures: operative versus nonoperative treatment. | The most appropriate treatment of Mason type II radial head fractures remains controversial. Recommended treatment has included closed reduction and immobilization, resection, or open reduction and internal fixation. The cases of 29 Mason type II radial head fractures treated at Naval Hospital Oakland from 1983 to 1989... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Fractures, Closed', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Radius', 'Radius Fractures', 'Retrospective Studies', 'Treatment Outcome'] | 1,403,245 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['A02.835.232.087.090.700'], ['C26.088.268.556', 'C26.404.562'], ['E05.318.372.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of copper addition on the superelastic behavior of Ni-Ti shape memory alloys for orthodontic applications. | Transformation temperatures and mechanical properties such as transformation stresses at different temperatures, superelasticity characteristics, and load cycling behavior have been investigated in NiTiCu orthodontic archwires with various copper concentrations. The results have been compared with the conventional NiTi... | ['Copper', 'Dental Alloys', 'Elasticity', 'Humans', 'Nickel', 'Orthodontic Appliances', 'Titanium'] | 10,490,682 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D25.339.208', 'J01.637.051.339.208'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['E06.658.453'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dynamic CT perfusion imaging with acetazolamide challenge for evaluation of patients with unilateral cerebrovascular steno-occlusive disease. | BACKGROUND AND PURPOSE: Perfusion CT (PCT) has the ability to measure quantitative values and produce maps of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). We assessed cerebral hemodynamics by using these parameters and acetazolamide challenge in patients with cerebrovascular sten... | ['Acetazolamide', 'Aged', 'Aged, 80 and over', 'Basal Ganglia', 'Blood Circulation', 'Blood Flow Velocity', 'Blood Volume', 'Brain', 'Carbonic Anhydrase Inhibitors', 'Carotid Artery, Internal', 'Carotid Stenosis', 'Cerebral Cortex', 'Cerebral Infarction', 'Cerebrovascular Disorders', 'Dominance, Cerebral', 'Female', 'H... | 17,032,859 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.211.200.885.287.249'], ['G09.330.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.188.130', 'G09.330.380.092'], ['A08.186.211'], ['D27.505.519.389.200'], ['A07.015.114.186.200.230'], ['C10.228.140.300.20... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Structural basis for the glycosyltransferase activity of the Salmonella | The Salmonella-secreted effector SseK3 translocates into host cells, targeting innate immune responses, including NF-êB activation. SseK3 is a glycosyltransferase that transfers an N-acetylglucosamine (GlcNAc) moiety onto the guanidino group of a target arginine, modulating host cell function. However, a lack of struct... | ['Amino Acid Sequence', 'Catalytic Domain', 'Crystallography, X-Ray', 'Glycosyltransferases', 'Humans', 'Models, Molecular', 'Protein Conformation', 'Salmonella Infections', 'Salmonella typhimurium', 'Sequence Alignment'] | 29,449,376 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309.742.225'], ['D08.811.913.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['G02.111.570.820.709'], ['C01.150.252.400.310.821'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Myocardial blood flow and VO2 in lambs with an aortopulmonary shunt during strenuous exercise. | To determine how much myocardial O2 consumption (VO2) would increase during an additional load on the heart in shunt as compared with control lambs, we studied 12 7-wk-old lambs with an aortopulmonary left-to-right shunt (59 +/- 3% of left ventricular output, mean +/- SE) and 11 control lambs during exercise at 80% of ... | ['Anastomosis, Surgical', 'Animals', 'Aorta', 'Atrial Function, Left', 'Blood Pressure', 'Coronary Circulation', 'Heart Rate', 'Oxygen Consumption', 'Physical Exertion', 'Pulmonary Artery', 'Sheep', 'Stroke Volume', 'Ventricular Function, Left'] | 8,456,994 | [['E04.035'], ['B01.050'], ['A07.015.114.056'], ['G09.330.040.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.100.324'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G03.680'], ['G11.427.683'], ['A07.015.114.715'], ['B01.050.150.900.649.313.500.380.791'], ['E01.370.370.380.150.700', 'G09.330.380.124.882']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Genesis and clinical aspects of functional diseases]. | A new approach of patients with functional disorders is proposed, as a result of an original experience: within a Department of internal Medicine we created a permanent place for listening to patients. This work is devoted to the genesis and clinical aspects of functional disorders. At the start, the functional disorde... | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychophysiologic Disorders'] | 6,651,097 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.592.700']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Skeletal muscle myopathy caused by triton WR-1339. | After administration (1 g/kg every other day for a total of five injections) of Triton WR-1339, the tonic, anterior (ALD) and phasic, posterior (PLD) latissimus dorsi muscles of the chicken underwent distinct pathological modifications. Some of the morphological alterations in the muscles paralleled those seen after ad... | ['Animals', 'Chickens', 'Cytoskeleton', 'Microscopy, Electron', 'Muscles', 'Muscular Diseases', 'Myofibrils', 'Polyethylene Glycols', 'Sarcoplasmic Reticulum', 'Surface-Active Agents'] | 6,119,838 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.284.430.214.190.750'], ['E01.370.350.515.402', 'E05.595.402'], ['A02.633', 'A10.690'], ['C05.651', 'C10.668.491'], ['A10.690.552.875', 'A11.284.430.214.190.750.620', 'A11.620.249.850', 'A11.620.500.500'], ['D02.033.455.250.700', 'D05.75... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The Top End Mental Health Services General Practice Clinic: an initiative for patients with serious mental illness. | OBJECTIVE: The aim of the present study was to provide an overview of the benefits of establishing a general practice clinic within a community mental health service. The clinic was established via collaboration between the Division of General Practice and the Mental Health Service.METHODS: Data collected over 19 month... | ['Ambulatory Care Facilities', 'Australia', 'Benchmarking', 'Community Mental Health Services', 'Health Promotion', 'Health Status', 'Humans', 'Mass Screening', 'Mental Disorders', 'Patient Care Team', 'Primary Health Care'] | 17,464,637 | [['N02.278.035'], ['Z01.639.100', 'Z01.678.100.373'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['I02.233.332.445', 'N02.421.726.407.579'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.9... | ['Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Diminished superoxide production of synovial fluid neutrophils in patients with rheumatoid arthritis following piroxicam treatment. | Superoxide production by polymorphonuclear leukocytes (PMNs) and macrophages was inhibited by piroxicam and other non-steroidal anti-inflammatory drugs both in vitro and in vivo. Hitherto, data have only been available on blood PMNs and macrophages. In order to investigate the situation in the joint, PMNs were isolated... | ['Arthritis, Rheumatoid', 'Humans', 'Neutrophils', 'Piroxicam', 'Superoxides', 'Synovial Fluid'] | 2,159,656 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['D02.886.665.500', 'D03.383.855.500'], ['D01.248.497.158.685.750.850', ... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Life After the Event: A Review of Basic Life Support Training for Parents Following Apparent Life-Threatening Events and Their Experience and Practices Following Discharge. | Apparent Life-Threatening Events (ALTEs) are a common presentation to paediatric hospitals and represent a significant cause of parental anxiety. Basic Life Support (BLS) training is recommended for all caregivers following ALTEs. This study aimed to assess the rate of caregiver BLS training and reviewed parents experi... | ['Anxiety', 'Cardiopulmonary Resuscitation', 'Child', 'Emergency Service, Hospital', 'Humans', 'Life Support Care', 'Parents', 'Patient Discharge'] | 28,737,312 | [['F01.470.132'], ['E02.365.647.110'], ['M01.060.406'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.440', 'N02.421.585.440'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E02.760.169.125', 'E02.760.400.610', 'N... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Current experience with thiamphenicol in uncomplicated gonococcal urethritis. | Use of thiamphenicol for the treatment of uncomplicated gonococcal urethritis was evaluated in 96 cases occurring between 1971 and 1975 and in 60 cases occurring between 1982 and 1983. Results in both groups of patients were nearly identical. Evidence indicates that gonococcal strains have not developed resistance to t... | ['Acute Disease', 'Chronic Disease', 'Gonorrhea', 'Humans', 'Male', 'Thiamphenicol', 'Urethritis'] | 6,523,321 | [['C23.550.291.125'], ['C23.550.291.500'], ['C01.150.252.400.625.275', 'C01.150.252.734.401', 'C01.221.812.281.401', 'C01.778.281.401', 'C12.294.668.281.401', 'C13.351.500.711.281.401'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.455.706.300.850', 'D02.455.426.559.389.565.175.850', 'D02.640.529.175.850'... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action. | Adriamycin-stimulated formation of .OH in sensitive and resistant subline of human breast tumor cells (MCF-7) has been examined by electron spin resonance spectroscopy. It was shown that adriamycin significantly stimulated the formation of .OH spin adducts [5,5-dimethyl-1-pyrroline N-oxide (DMPO)-OH] in the sensitive c... | ['Breast Neoplasms', 'Catalase', 'Cell Line', 'Colony-Forming Units Assay', 'Cyclic N-Oxides', 'Deferoxamine', 'Doxorubicin', 'Drug Resistance', 'Electron Spin Resonance Spectroscopy', 'Female', 'Free Radicals', 'Glutathione Peroxidase', 'Humans', 'Hydroxides', 'Hydroxyl Radical', 'Oxygen', 'Superoxide Dismutase', 'Tum... | 2,820,475 | [['C04.588.180', 'C17.800.090.500'], ['D08.811.682.732.332'], ['A11.251.210'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['D03.661.243'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['G07.690.773.984'], [... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Leukocytes in the cervix: a quantitative evaluation of cervicitis. | OBJECTIVE: To quantify the numbers of leukocytes in the normal cervix and relate these numbers to the diagnosis of cervicitis.METHODS: Isolated cell suspensions were prepared from cervical tissue recovered at hysterectomy from 37 women who had no obvious cervical disease. The percentages of CD45+ cells (leukocytes) in ... | ['Cell Count', 'Cervix Uteri', 'Female', 'Flow Cytometry', 'Humans', 'Leukocyte Common Antigens', 'Leukocytes', 'Middle Aged', 'Uterine Cervicitis'] | 9,611,010 | [['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A05.360.319.679.256'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alveolar Macrophages Can Control Respiratory Syncytial Virus Infection in the Absence of Type I Interferons. | Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections. Immunity to RSV is initiated upon detection of the virus by pattern recognition receptors, such as RIG-I-like receptors. RIG-I-like receptors signal via MAVS to induce the synthesis of proinflammatory mediators, including type I ... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Cells, Cultured', 'Cytokines', 'Inflammation Mediators', 'Interferon Type I', 'Macrophages, Alveolar', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Receptor, Interferon alpha-beta', 'Respiratory Syncytial Virus Infections', 'Respiratory Syncytial Viruses', 'Signa... | 27,423,203 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D23.469'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['A11.329.372.600', 'A11.627.482.600', 'A11.733.397.600', 'A15.382.670.522.600', 'A15.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Single-cell transcriptional analysis of neuronal progenitors. | The extraordinary cellular heterogeneity of the mammalian nervous system has largely hindered the molecular analysis of neuronal identity and diversity. In order to uncover mechanisms involved in neuronal differentiation and diversification, we have monitored the expression profiles of individual neurons and progenitor... | ['Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Cell Differentiation', 'Cell Separation', 'Cells, Cultured', 'DNA, Complementary', 'DNA-Binding Proteins', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Humans', 'Lasers', 'Mice', 'Neuroglia', 'Neurons', 'Neurons, Afferent', 'Nucl... | 12,718,852 | [['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['G04.152'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.251'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.776.260'], ['E05.393.332'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Partial purification from hot dogs of N-nitroso compound precursors and their mutagenicity after nitrosation. | Hot dogs contain apparent N-nitroso compounds (ANC) and ANC precursors (ANCP). ANCP purification was followed by nitrosation, sulfamic acid treatment, and analysis for ANC. Aqueous hot dog extracts were adsorbed on silica gel, which was eluted with MeCN and MeOH. The MeOH eluate was adsorbed on cation exchange resin (H... | ['Amino Acids', 'Chromatography, High Pressure Liquid', 'Drug Stability', 'Gas Chromatography-Mass Spectrometry', 'Glucose', 'Meat Products', 'Mutagenicity Tests', 'Mutagens', 'Nitrosation', 'Nitroso Compounds', 'Sucrose'] | 16,848,563 | [['D12.125'], ['E05.196.181.400.300'], ['E05.916.330'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D09.947.875.359.448'], ['G07.203.300.600.500', 'J02.500.600.500'], ['E05.393.560', 'E05.940.560'], ['D27.888.569.468'], ['G02.111.595', 'G02.607.598', 'G03.558'], ['D02.654'], ['D09.698.629.305.770', 'D09.947.750.770']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Breast cancer in Argentina: case-control study with special reference to meat eating habits. | An exploratory case-control study of the role of diet in the etiology of breast cancer was conducted in Buenos Aires, Argentina, where the mortality rate for this disease is high and the consumption of meat, mainly beef, is unusually elevated (76.2 kilograms per head were reported for 1987). One hundred and ninety-six ... | ['Adult', 'Aged', 'Argentina', 'Body Weight', 'Breast Neoplasms', 'Case-Control Studies', 'Diet', 'Female', 'Humans', 'Meat', 'Middle Aged', 'Odds Ratio', 'Regression Analysis', 'Risk Factors'] | 1,857,455 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.757.077'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.203.650.240'], ['B01.0... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Relationship between scanning laser polarimetry with enhanced corneal compensation and with variable corneal compensation. | PURPOSE: To evaluate the structure-function relationships between retinal sensitivity measured by Humphrey visual field analyzer (HVFA) and the retinal nerve fiber layer (RNFL) thickness measured by scanning laser polarimetry (SLP) with variable corneal compensation (VCC) and enhanced corneal compensation (ECC) in glau... | ['Algorithms', 'Birefringence', 'Cornea', 'Cross-Sectional Studies', 'Diagnostic Techniques, Ophthalmological', 'Female', 'Glaucoma', 'Humans', 'Intraocular Pressure', 'Lasers', 'Male', 'Middle Aged', 'Nerve Fibers', 'Optic Nerve Diseases', 'Prospective Studies', 'Retinal Ganglion Cells', 'Vision Disorders', 'Visual Fi... | 18,323,701 | [['G17.035', 'L01.224.050'], ['G01.590.080'], ['A09.371.060.217'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.380'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E07.632.490', 'E07.710.520'], ['M01.060.116.630'], ['A08.675.542', 'A11.671.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes. | Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that plays an important role in multiple sclerosis (MS). However, mechanisms by which CNTF expression could be increased in the brain are poorly understood. Recently we have discovered anti-inflammatory and immunomodulatory activities of sodium benzo... | ['Animals', 'Astrocytes', 'Ciliary Neurotrophic Factor', 'Cinnamomum zeylanicum', 'Cyclic AMP Response Element-Binding Protein', 'Cyclic AMP-Dependent Protein Kinases', 'Encephalomyelitis, Autoimmune, Experimental', 'Enzyme Activation', 'Food Preservatives', 'Gene Knockdown Techniques', 'Humans', 'Isoquinolines', 'Mice... | 26,399,250 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['D12.644.276.860.212', 'D12.776.467.860.212', 'D12.776.631.600.212', 'D23.529.850.212'], ['B01.650.940.800.575.912.250.595.400.149.500'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ophthalmic drug delivery through contact lenses. | PURPOSE: Currently available ophthalmic drug delivery systems are inefficient and may lead to side effects. To increase efficiency and reduce side effects, the authors propose disposable particle-laden soft contact lenses for ophthalmic drug delivery.METHODS: The essential idea is to encapsulate the ophthalmic drug for... | ['Anesthetics, Local', 'Contact Lenses, Hydrophilic', 'Disposable Equipment', 'Drug Delivery Systems', 'Emulsions', 'Gels', 'Lidocaine', 'Microscopy, Electron, Scanning', 'Ophthalmic Solutions', 'Pilot Projects', 'Polyhydroxyethyl Methacrylate'] | 15,223,815 | [['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['E07.632.500.276.360'], ['E07.252'], ['E02.319.300'], ['D20.280.260', 'D26.255.165.260'], ['D20.280.320', 'D26.255.165.320'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D26... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Modified extraperitoneal uterosacral ligament suspension for prevention of vault prolapse after vaginal hysterectomy. | INTRODUCTION AND HYPOTHESIS: During vaginal hysterectomy, extraperitoneal uterosacral ligament suspension (ULS) bites can be taken before removing the uterus. We evaluated this modified extraperitoneal ULS for vault prolapse prevention.METHODS: Study period was 3.5 years. Fifty-one women with third- and fourth-degree p... | ['Aged', 'Female', 'Humans', 'Hysterectomy, Vaginal', 'Ligaments', 'Middle Aged', 'Pelvic Organ Prolapse', 'Sacrum', 'Uterine Prolapse', 'Uterus'] | 29,777,272 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399.380'], ['A02.513', 'A10.165.669'], ['M01.060.116.630'], ['C23.300.842.624'], ['A02.835.232.834.717'], ['C13.351.500.852.833', 'C23.300.842.624.750'], ['A05.360.319.679']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effect of JNK pathway in apoptosis of PC12 cell by MPP+]. | OBJECTIVE: To study the toxicity and its mechanisms of 1-methyl-4-phenylpyridinium ion (MPP+) on pheochromocytoma PC12 cells.METHODS: PC12 cells were cultured in vitro, and poisoned by 100, 300, 500 micromol/L MPP+. Western blot was performed to determine the level of phosphorylated c-Jun-N-terminal kinase/stress activ... | ['1-Methyl-4-phenylpyridinium', 'Animals', 'Anthracenes', 'Apoptosis', 'MAP Kinase Signaling System', 'PC12 Cells', 'Rats'] | 21,434,327 | [['D03.383.725.762.550'], ['B01.050'], ['D02.455.426.559.847.117', 'D04.615.117'], ['G04.146.954.035'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['A11.251.210.190.750', 'A11.251.860.180.750', 'A11.299.500'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CD38 Is Required for Neural Differentiation of Mouse Embryonic Stem Cells by Modulating Reactive Oxygen Species. | CD38 is a multifunctional membrane enzyme and the main mammalian ADP-ribosyl cyclase, which catalyzes the synthesis and hydrolysis of cADPR, a potent endogenous Ca(2+) mobilizing messenger. Here, we explored the role of CD38 in the neural differentiation of mouse embryonic stem cells (ESCs). We found that the expressio... | ['ADP-ribosyl Cyclase 1', 'Animals', 'Cell Differentiation', 'Cells, Cultured', 'Gene Knockdown Techniques', 'Membrane Glycoproteins', 'Mice', 'Mouse Embryonic Stem Cells', 'Neurons', 'Reactive Oxygen Species'] | 26,012,865 | [['D08.811.277.450.430.400.060.500', 'D12.776.543.550.045'], ['B01.050'], ['G04.152'], ['A11.251'], ['E05.393.335.500'], ['D12.776.395.550', 'D12.776.543.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.872.700.250.875'], ['A08.675', 'A11.671'], ['D01.339.431', 'D01.650.775']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synergistic ROS-Associated Antimicrobial Activity of Silver Nanoparticles and Gentamicin Against Staphylococcus epidermidis | Introduction: Increasing bacteria resistance to antibiotics is a major problem of healthcare system. There is a need for solutions that broaden the spectrum of bactericidal agents improving the efficacy of commonly used antibiotics. One of the promising directions of search are silver nanoparticles (obtained by differe... | ['Anti-Bacterial Agents', 'Biofilms', 'Culture Media', 'Gentamicins', 'Humans', 'Metal Nanoparticles', 'Microbial Sensitivity Tests', 'Reactive Oxygen Species', 'Silver', 'Staphylococcus epidermidis'] | 32,547,013 | [['D27.505.954.122.085'], ['A20.593', 'G06.120'], ['D27.720.470.305', 'E07.206'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.512.600.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D01.339.431', 'D01.650.775'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Validation of the Scale of Basic Psychological Needs towards Physical Exercise, with the Inclusion of Novelty. | The purpose of this study was to validate and adapt to the Spanish context of Physical Education, the Spanish version of the Scale of Basic Psychological Needs in the context of physical exercise, with the incorporation of novelty to the scale. The sample that took part in the study was 2372 people from 16 to 48 years ... | ['Adolescent', 'Adult', 'Exercise', 'Exploratory Behavior', 'Female', 'Humans', 'Male', 'Middle Aged', 'Needs Assessment', 'Psychological Tests', 'Psychometrics', 'Reproducibility of Results', 'Spain', 'Young Adult'] | 31,963,663 | [['M01.060.057'], ['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.387', 'F01.658.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['F04.711'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A Stress Management Program for Higher Risk Medical Students: Preliminary Findings. | Approximately 10 % of first year medical students have clinically relevant anxiety or depression which may affect academic success and quality of life. This study tested the effects of a stress management intervention on indicators of anxiety, depression and self-efficacy in self-selected first year medical students. F... | ['Adaptation, Psychological', 'Anxiety', 'Depression', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Quality of Life', 'Self Efficacy', 'Stress, Psychological', 'Students, Medical', 'Young Adult'] | 26,969,177 | [['F01.058'], ['F01.470.132'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['F01.752.747.792.700'], ['F01.145.126.990', 'F02.830.900'], ['M01.848.769.602'], ['M01.060.116.815']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Case-control assessment of diet and lung cancer risk in African Americans and Mexican Americans. | In this case-control study we determined whether dietary differences underlie some of the ethnic and sex differences in US lung cancer rates. We examined the relationship between diet and lung cancer development in 137 lung cancer cases (93 African Americans and 44 Mexican Americans) and 187 controls (78 African Americ... | ['African Americans', 'Case-Control Studies', 'Diet', 'Dietary Fats', 'Dietary Fiber', 'Energy Intake', 'Female', 'Fruit', 'Humans', 'Incidence', 'Logistic Models', 'Lung Neoplasms', 'Male', 'Mexican Americans', 'Risk Factors', 'Sex Factors', 'Smoking', 'Social Class', 'Vegetables'] | 9,427,982 | [['M01.686.508.100.100', 'M01.686.754.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.203.650.240'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.650.240.340'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. | The Cre/loxP site-specific recombination system derived from bacteriophage P1 provides a convenient tool for directed modifications of genomes in various organisms. To exploit Cre-mediated manipulation of mouse genomic sequences at the zygote stage, we have developed a transgenic mouse line carrying the CAG-cre transge... | ['Animals', 'Chloramphenicol O-Acetyltransferase', 'Female', 'Gene Deletion', 'Genes, Reporter', 'Integrases', 'Male', 'Mice', 'Mice, Transgenic', 'Oocytes', 'Recombination, Genetic', 'Transgenes', 'Viral Proteins'] | 9,268,708 | [['B01.050'], ['D08.811.913.050.134.170'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.360.340.024.340.435'], ['D08.811.739.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['A05.360.490.690.680', 'A11.497.497.600'], ['G05.728'], ['G05.360... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Irsogladine maleate regulates gap junctional intercellular communication-dependent epithelial barrier in human nasal epithelial cells. | The airway epithelium of the human nasal mucosa acts as the first physical barrier that protects against inhaled substances and pathogens. Irsogladine maleate (IM) is an enhancer of gastric mucosal protective factors via upregulation of gap junctional intercellular communication (GJIC). GJIC is thought to participate i... | ['Antineoplastic Agents', 'Cell Communication', 'Epithelial Cells', 'Gap Junctions', 'Gene Expression', 'Glycyrrhetinic Acid', 'Humans', 'Interleukin-8', 'Nasal Mucosa', 'Oleic Acids', 'Tight Junction Proteins', 'Triazines', 'Tumor Necrosis Factor-alpha'] | 25,652,184 | [['D27.505.954.248'], ['G04.085'], ['A11.436'], ['A11.284.149.165.420.471'], ['G05.297'], ['D02.455.849.919.530.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D12.776.467.374.200.120.800', 'D12.776.467.374.465.246', 'D23.125.300.120.800', 'D23.469.200... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of suicide cases in Turkey, 2007-2012. | BACKGROUND: The aim of this study was to determine the demographic and sociocultural characteristics of suicide attempts by using data from the Turkish Statistical Institute. It is our intent that the work data may contribute to the national suicide data and the development of suicide prevention policies.MATERIAL AND M... | ['Adult', 'Age Distribution', 'Cause of Death', 'Cities', 'Educational Status', 'Female', 'Geography', 'Humans', 'Male', 'Middle Aged', 'Suicide', 'Turkey', 'Young Adult'] | 24,732,406 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['N01.824.196'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Clinical features of familial ovarian cancer lacking mutations in BRCA1 or BRCA2. | PURPOSE OF INVESTIGATION: The purpose of the present study was to identify the clinical and pathologic features of ovarian cancers in patients who have a family history of breast or ovarian cancer but who do not have a mutation in the BRCA1 or BRCA2 gene.METHODS: 303 patients with ovarian cancer were reviewed for clini... | ['Adult', 'Case-Control Studies', 'Female', 'Genes, BRCA1', 'Genes, BRCA2', 'Genetic Predisposition to Disease', 'Humans', 'Middle Aged', 'Mutation', 'Neoplasm Staging', 'Ovarian Neoplasms', 'Poland'] | 15,053,073 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.360.340.024.340.375.249.100', 'G05.360.340.024.340.415.400.100'], ['G05.360.340.024.340.375.249.105', 'G05.360.340.024.340.415.400.105'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Activity of polynucleotide phosphorylase in ribosomal fraction of rat liver]. | A method of isolating polynucleotidephosphorylase (PNPase) containing polyribosome fraction from rat liver is described. PNPase is found to be bind to RNA in polyribosomes with weak electrostatic bonds which are easily broken down in a weak alkaline medium with ionic strength more than 0.1 beta-22P-labelled ADP, GDP, U... | ['Animals', 'Hydrogen-Ion Concentration', 'Liver', 'Macromolecular Substances', 'Polyribonucleotide Nucleotidyltransferase', 'Polyribosomes', 'Protein Binding', 'RNA', 'Rats', 'Ribosomes', 'Structure-Activity Relationship'] | 1,115 | [['B01.050'], ['G02.300'], ['A03.620'], ['D05'], ['D08.811.913.696.445.735.532'], ['A11.284.430.214.190.875.811.740'], ['G02.111.679', 'G03.808'], ['D13.444.735'], ['B01.050.150.900.649.313.992.635.505.700'], ['A11.284.430.214.190.875.811'], ['G02.111.830', 'G07.690.773.997']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The innermost cells of the outer root sheath in human anagen hair follicles undergo specialized keratinization mediated by apoptosis. | The innermost cell layer of the outer root sheath (IORS) is a special single cell layer located just outside Henle's layer. In situ end-labeling immunohistochemistry for apoptosis showed that labeled cells were most consistently located in the IORS from the suprabulbar portion to the infundibulum of anagen terminal hai... | ['Adult', 'Apoptosis', 'Female', 'Hair Follicle', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Microscopy, Electron', 'Middle Aged'] | 9,694,621 | [['M01.060.116'], ['G04.146.954.035'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
T-helper type-1-dominated lymph node responses induced in C57BL/6 mice by optimally irradiated cercariae of Schistosoma mansoni are down-regulated after challenge infection. | Following a single percutaneous vaccination with optimally irradiated cercariae of Schistosoma mansoni, C57BL/6 mice mount a T-helper type-1 (Th1) lymphocyte-dominant immune response and are highly resistant to challenge infection. In this study, we show that, besides interferon-gamma (IFN-gamma), lymph node (LN) cells... | ['Animals', 'Antigens, Helminth', 'Cell Division', 'Cells, Cultured', 'Cytokines', 'Female', 'Immunization', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-2', 'Interleukin-4', 'Lymph Nodes', 'Mice', 'Mice, Inbred C57BL', 'Schistosoma mansoni', 'Schistosomiasis mansoni', 'Th1 Cells', 'Th2 Cells'] | 7,751,008 | [['B01.050'], ['D23.050.223'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['D12.644.276.374.440.893', 'D12.644.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Metal complexes of chiral pentaazacrowns as conformational templates for beta-turn recognition. | Examples of reverse turns as recognition motifs in biological systems can be found in high-resolution crystal structures of antibody-peptide complexes. Development of peptidomimetics is often based on replacing the amide backbone of peptides by sugar rings, steroids, benzodiazepines, or other hetero- and carbocycles. I... | ['Computer Simulation', 'Drug Design', 'Heterocyclic Compounds', 'Ligands', 'Models, Molecular', 'Molecular Conformation', 'Molecular Mimicry', 'Oligopeptides', 'Organometallic Compounds', 'Peptides, Cyclic', 'Stereoisomerism', 'Thermodynamics'] | 12,602,952 | [['L01.224.160'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D03'], ['D27.720.470.480'], ['E05.599.595'], ['G02.111.570.820'], ['G02.111.560', 'G05.545', 'G16.012.750.500'], ['D12.644.456'], ['D02.691'], ['D04.345.566', 'D12.644.641'], ['G02.607.445.682'], ['G01.906']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Electronographic changes in general anesthesia]. | Using the electronograph, a special device which is capable to record luminous effects of the Corona and Kirlian types, the authors investigated 9 patients (6 males and 3 females) both before and during anesthetic sleep, and after arousal from anesthesia. In all the patients the studies were made on black-and-white, as... | ['Anesthesia, General', 'Anesthetics', 'Energy Metabolism', 'Energy Transfer', 'Humans'] | 6,220,435 | [['E03.155.197'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['G03.295'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Production of oxychemicals from precipitated hardwood lignin. | Lignin is a major byproduct in the biomass-to-ethanol process. The lignin produced from acid treatment of biomass has characteristics suitable for further conversion to organic chemicals. It is free of contaminants and has a relatively low molecular weight. In this study, catalytic oxidative conversion of the acid-solu... | ['Aldehydes', 'Benzaldehydes', 'Biomass', 'Biotechnology', 'Chemical Precipitation', 'Ethanol', 'Hydrogen-Ion Concentration', 'Ketones', 'Lignin', 'Oxidation-Reduction', 'Wood'] | 11,963,899 | [['D02.047'], ['D02.047.222'], ['G16.500.275.157.100', 'N06.230.124.100'], ['H01.158.550', 'J01.897.120'], ['E05.196.150', 'G02.159'], ['D02.033.375'], ['G02.300'], ['D02.522'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['G02.700', 'G03.295.531'], ['A18.450... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Diagnosis in dermatology]. | We summarize here some of the specificities of diagnosis in dermatology for the general practitioner. Starting with clinical cases, we analyze the steps that the dermatologist uses to diagnose skin disorders. The initial clinical examination of primary and secondary skin lesions leads to a differential diagnosis. Subse... | ['Adult', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Skin Diseases'] | 17,552,266 | [['M01.060.116'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact Mineralization of Chokeberry and Cranberry Fruit Juices Using a New Functional Additive on the Protection of Bioactive Compounds and Antioxidative Properties. | Chicken eggshells can be used as an attractive dietary source of mineral compounds, including calcium (Ca). However, the effects of chicken eggshell powder (CESP) on berry fruit juices have not been studied to date. Therefore, the objective of this study was to evaluate the effect of its addition to juices from chokebe... | ['Animals', 'Antioxidants', 'Calcium', 'Chickens', 'Chromatography, High Pressure Liquid', 'Egg Shell', 'Food Additives', 'Fruit and Vegetable Juices', 'Hydrogen-Ion Concentration', 'Minerals', 'Phytochemicals', 'Polyphenols', 'Prunus', 'Vaccinium macrocarpon'] | 32,033,071 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.300'], ['A13.316'], ['D27.720.372.300', 'G07.203.300.514.500', 'J02.500.514.500'], ['G07.203.100.606', 'J0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Predominance of beta 3-adrenergic component in catecholamine activation of lipolysis in garden dormouse adipocytes. | The beta 3-adrenoceptor (AR) agonists are potent activators of lipolysis in white adipose tissue. beta-AR agonists were tested here on the lipolytic activity of a hibernator, the garden dormouse (Eliomys quercinus L.). All the agonists exhibited full intrinsic activity; the most potent was the beta 3-AR agonist BRL-373... | ['Adipocytes', 'Adrenergic beta-Agonists', 'Adrenergic beta-Antagonists', 'Animals', 'Catecholamines', 'Female', 'Iodocyanopindolol', 'Lipolysis', 'Male', 'Pindolol', 'Propanolamines', 'Receptors, Adrenergic, beta', 'Rodentia'] | 7,909,204 | [['A11.329.114'], ['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['D02.033.100.624.698.699.420', 'D02.033.755.624.698.699.420', 'D02.092.063.624.698.699.420'], ['G02.111.534'... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The DNA-binding ability of HIVEP3/KRC decreases upon activation of V(D)J recombination. | Somatic V(D)J recombination of the immune receptor genes is mediated by the recombination signal sequence (RSS) and the recombination-activating genes RAG1 and RAG2. Previously, proteins binding specifically to the RSS have been characterized in nuclear extracts of T and B lymphocytes. Further elucidation of the role o... | ['Antibody Specificity', 'B-Lymphocytes', 'Binding Sites', 'DNA-Binding Proteins', 'Enhancer Elements, Genetic', 'Humans', 'NF-kappa B', 'Protein Binding', 'Receptors, Antigen, B-Cell', 'Recombination, Genetic', 'U937 Cells'] | 11,685,469 | [['G12.100'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G02.111.570.120'], ['D12.776.260'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.500.6... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between Dietary Xanthophyll (Lutein and Zeaxanthin) Intake and Early Age-Related Macular Degeneration: The Atherosclerosis Risk in Communities Study. | PURPOSE: To examine the association between xanthophyll intake and prevalent early age-related macular degeneration (AMD) using data from the Atherosclerosis Risk in Communities Study (n = 10,295). Potential effect modification by genetic polymorphisms and biomarkers of high-density lipoprotein (HDL) metabolism was exp... | ['Aged', 'Atherosclerosis', 'Complement Factor H', 'Diet', 'Female', 'Genotype', 'Humans', 'Lipoproteins, HDL', 'Macular Degeneration', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Prevalence', 'Proteins', 'Retinal Drusen', 'Xanthophylls'] | 28,332,910 | [['M01.060.116.100'], ['C14.907.137.126.307'], ['D12.776.124.486.274.920.325.200', 'D12.776.124.790.223.200', 'D12.776.377.715.182.200'], ['G07.203.650.240'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.432', 'D12.776.521.479'], ['C11.768.585.439'], ['M01.060.116.630'], ['G05.365.795.598'], ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhancement and metastasis after immunotherapy of ovine squamous-cell carcinoma. | Extracts of ovine squamous-cell carcinoma (OSCC) prepared by different procedures, were injected at varying concentrations into 184 tumour-bearing sheep. At a total protein of 0.5 mg and greater, there was significant enhancement and metastasis in all 120 sheep examined. Extracts of OSCC containing less than 0.5 mg pro... | ['Animals', 'Antigens, Neoplasm', 'Carcinoma, Squamous Cell', 'Female', 'Immunotherapy', 'Male', 'Neoplasm Metastasis', 'Neoplasm Proteins', 'Sheep', 'Sheep Diseases', 'Skin Neoplasms'] | 708,569 | [['B01.050'], ['D23.050.285'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.095.465.425'], ['C04.697.650', 'C23.550.727.650'], ['D12.776.624'], ['B01.050.150.900.649.313.500.380.791'], ['C22.836'], ['C04.588.805', 'C17.800.882']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA damage and p53-mediated growth arrest in human cells treated with platinum nanoparticles. | AIM: Platinum-based therapeutic agents are widely used in medicine. Thus, a thorough understanding of their mechanism of action in cells is warranted. This study investigates the uptake and bioactivity (e.g., cytotoxicity, genotoxicity and protein expression) of platinum nanoparticles (Pt-NPs, approximately 5-8 nm in s... | ['Antineoplastic Agents', 'Apoptosis', 'Cell Cycle', 'Cell Line, Tumor', 'Cyclin-Dependent Kinase Inhibitor p21', 'DNA Damage', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Metal Nanoparticles', 'Platinum', 'Tumor Suppressor Protein p53'] | 20,025,464 | [['D27.505.954.248'], ['G04.146.954.035'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['G05.200'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparing Health Status, Health Trajectories and Use of Health and Social Services between Children with and without Developmental Disabilities: A Population-based Longitudinal Study in Manitoba. | BACKGROUND: Little information exists on health of children with developmental disabilities (DDs) in the Canadian province of Manitoba.METHOD: The present authors linked 12 years of administrative data and compared health status, changes in health and access to health and social services between children with (n = 1877... | ['Child', 'Child, Preschool', 'Developmental Disabilities', 'Female', 'Health Services', 'Health Services Accessibility', 'Health Status', 'Humans', 'Longitudinal Studies', 'Male', 'Manitoba', 'Social Work', 'Socioeconomic Factors'] | 27,041,130 | [['M01.060.406'], ['M01.060.406.448'], ['F03.625.421'], ['N02.421'], ['N04.590.374.350', 'N05.300.430'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['Z01.107.567.176.41... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Hes1 in the somatic cells of the murine ovary is necessary for oocyte survival and maturation. | The Notch pathway plays an important role in ovary development in invertebrates like Drosophila. However its role for the mammalian ovary is unclear. Mammalian Hes genes encode transcriptional factors that mediate many of the activities of the Notch pathway. Here, we have studied the function of Hes1 during embryonic d... | ['Animals', 'Apoptosis', 'Basic Helix-Loop-Helix Transcription Factors', 'Cell Count', 'Cell Differentiation', 'Cell Proliferation', 'Cell Size', 'Cell Survival', 'Endothelial Cells', 'Female', 'Fertility', 'Gene Expression Regulation, Developmental', 'Granulosa Cells', 'Homeodomain Proteins', 'Mice', 'Mice, Knockout',... | 23,274,689 | [['B01.050'], ['G04.146.954.035'], ['D12.776.260.103', 'D12.776.930.125'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.325'], ['G04.346'], ['A11.436.275'], ['G08.686.210'], ['G05.308.310'], ['A05.360.319.114.630.535.200', 'A06.300.312.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peribulbar versus general anesthesia for horizontal strabismus surgery. | PURPOSE: To compare the results of strabismus surgery under peribulbar and general anesthesia in cases of small and moderate angle of horizontal strabismus.METHODS: Medical records of eighty-four patients with small and moderate angle horizontal strabismus who underwent strabismus surgery were reviewed. Forty-two patie... | ['Adolescent', 'Adult', 'Anesthesia, General', 'Anesthetics, Local', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Postoperative Period', 'Preoperative Care', 'Reference Values', 'Statistics, Nonparametric', 'Strabismus', 'Treatment Outcome', 'Young Adult'] | 18,641,820 | [['M01.060.057'], ['M01.060.116'], ['E03.155.197'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.614.750', 'N02... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rebasing the Medicare payment for dialysis: rationale, challenges, and opportunities. | After Medicare's implementation of the bundled payment for dialysis in 2011, there has been a predictable decrease in the use of intravenous drugs included in the bundle. The change in use of erythropoiesis-stimulating agents, which decreased by 37% between 2007, when its allowance in the bundle was calculated, and 201... | ['Administration, Intravenous', 'Ambulatory Care Facilities', 'Cost Control', 'Cost-Benefit Analysis', 'Hematinics', 'Humans', 'Medicare', 'Reimbursement Mechanisms', 'Renal Dialysis', 'Renal Insufficiency, Chronic', 'United States'] | 25,189,926 | [['E02.319.267.082'], ['N02.278.035'], ['N03.219.151.160'], ['N03.219.151.125'], ['D27.505.954.502.543'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['N03.219.521.710.305'], ['E02.870.300', 'E02.912.800'], ['C12.777.419.780.750', 'C13.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Inhibition of mouse liver alcohol dehydrogenase by methyl N-butyl ketone. | Methyl N-butyl ketone (MNBK) inhibited the activity of mouse liver alcohol dehydrogenase (LADH) in vitro. Ethanol elimination was reduced in MNBK-treated mice as compared to controls. Ethanol-induced induced loss of righting reflex was significantly prolonged in mice pretreated with MNBK. | ['Alcohol Dehydrogenase', 'Alcohol Oxidoreductases', 'Animals', 'Brain', 'Chromatography, Gas', 'Ethanol', 'In Vitro Techniques', 'Ketones', 'Liver', 'Male', 'Metabolic Clearance Rate', 'Methyl n-Butyl Ketone', 'Mice', 'Time Factors'] | 3,159,129 | [['D08.811.682.047.820.250'], ['D08.811.682.047'], ['B01.050'], ['A08.186.211'], ['E05.196.181.349'], ['D02.033.375'], ['E05.481'], ['D02.522'], ['A03.620'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['D02.522.520.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['G01.910.857']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Model for Temporal Dynamics of Brown Rot Spreading in Fruit Orchards. | Brown rot, caused by Monilinia spp., is a major disease of stone fruit and, in favorable environmental conditions and in the absence of fungicide treatments, it causes important economic losses. In the present work, we propose a modification of classical susceptible, exposed, infectious and removed compartmental models... | ['Ascomycota', 'France', 'Fruit', 'Models, Theoretical', 'Plant Diseases', 'Prunus persica'] | 29,182,471 | [['B01.300.107'], ['Z01.542.286'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.599'], ['G15.610'], ['B01.650.940.800.575.912.250.859.937.500.625.750']] | ['Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Change perspective to increase diagnostic accuracy of ultrasonography in calcium pyrophosphate dehydrate deposition disease! A new approach: the axial scan of the meniscus. | Ultrasonography (US) is a relevant tool in the study of calcium pyrophosphate dihydrate (CPP) deposition disease. However, differential diagnosis of hyperechoic deposits within the fibrocartilage can be difficult; moreover, US study is limited by the need of an adequate acoustic window. We describe a US scanning techni... | ['Calcium Pyrophosphate', 'Chondrocalcinosis', 'Crystallization', 'Humans', 'Knee Joint', 'Meniscus', 'Predictive Value of Tests', 'Sensitivity and Specificity', 'Ultrasonography'] | 25,829,191 | [['D01.029.260.700.675.374.075.150', 'D01.029.260.700.675.374.775.150.150', 'D01.146.360.150', 'D01.695.625.675.650.075.150', 'D01.695.625.675.650.775.150.150'], ['C05.550.114.264', 'C05.550.354.125'], ['E05.196.300', 'G02.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['A02.165.308.538', ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quality assurance in DNR (do not resuscitate) decisions--the role of chaplaincy: a case report and a 92 patient group study. | This paper describes 10 indicators of quality assurance for DNR decisions developed by a New England hospital's chaplaincy. It then looks at how these 10 indicators were applied to a specific case and subsequently to the hospital's group of 92 terminal cases. Recommendations were also made for each responsibility group... | ['Chaplaincy Service, Hospital', 'Decision Making', 'Ethics, Institutional', 'Hospital Bed Capacity, 500 and over', 'Hospital Departments', 'Interdepartmental Relations', 'Massachusetts', 'Professional Staff Committees', 'Quality Assurance, Health Care', 'Resuscitation', 'Role', 'Terminal Care'] | 10,292,622 | [['N02.278.216.500.968.270', 'N04.452.442.452.422.270'], ['F02.463.785.373'], ['K01.752.566.479.168', 'N05.350.325'], ['N02.278.306.472.300'], ['N02.278.216.500.968', 'N04.452.442.452.422'], ['N04.452.822.388'], ['Z01.107.567.875.550.510'], ['N04.452.758.788', 'N05.700.685'], ['N04.761.700', 'N05.700'], ['E02.365.647']... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Colony opacity, hemadsorption, hemolysis, and mitogenicity are not associated with virulence of Mycoplasma pulmonis. | Colony opacity, hemadsorption and hemolysis of erythrocytes, and the ability of whole mycoplasmal cells to induce a blastogenic response when incubated with C3H/HeN or C57BL/6 mouse lymphocytes were examined for 18 strains of Mycoplasma pulmonis to determine if any of these characteristics could be associated with viru... | ['Animals', 'Erythrocytes', 'Hemolysis', 'Lymphocyte Activation', 'Mice', 'Mycoplasma', 'Mycoplasma Infections', 'Species Specificity'] | 3,397,189 | [['B01.050'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.550.403', 'G12.122.545'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050.150.900.649.313.992.635.505.500'], ['B03.440.860.580.553.553'], ['C01.150.252.400.610.610'], ['G16.824']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cultured epithelial autografts in extensive burn coverage of severely traumatized patients: a five year single-center experience with 30 patients. | OBJECTIVE: We report recent five-year experience in a large, single center series of severely burned and otherwise traumatized patients given cultured epithelial autografts (CEA) from a single commercial laboratory.SUMMARY BACKGROUND DATA: Initial optimism over CEA application has been tempered by subsequent reports as... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Analysis of Variance', 'Anti-Infective Agents, Local', 'Bandages', 'Body Surface Area', 'Burns', 'Burns, Inhalation', 'Cerium', 'Child', 'Child, Preschool', 'Culture Techniques', 'Drug Combinations', 'Epithelium', 'Female', 'France', 'Graft Survival', 'Humans', 'Male', 'M... | 10,751,706 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.954.122.187'], ['E07.101'], ['E01.370.600.115.100.231', 'E05.041.124.231', 'G07.100.100.231'], ['C26.200'], ['C26.200.322'], ['D01.268.558.362.249'... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Combined transarterial chemoembolization and microwave ablation versus transarterial chemoembolization in BCLC stage B hepatocellular carcinoma. | PURPOSE: We aimed to compare the clinical effectiveness of combination therapy of transarterial chemoembolization (TACE) and microwave ablation (MWA) with TACE monotherapy in BCLC stage B HCC patients with tumor size ?7 cm and tumor number ?5.METHODS: We retrospectively reviewed 150 BCLC stage B HCC patients who had re... | ['Ablation Techniques', 'Carcinoma, Hepatocellular', 'Chemoembolization, Therapeutic', 'Combined Modality Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Kaplan-Meier Estimate', 'Liver', 'Liver Neoplasms', 'Male', 'Microwaves', 'Middle Aged', 'Retrospective Studies', 'Severity of Illness Index', 'Treatment Outcome'... | 29,792,289 | [['E04.014'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.520.360.150', 'E02.926.500.150'], ['E02.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phosphatidylserine decarboxylase from Clostridium butyricum. | Phosphatidylserine decarboxylase activity has been characterized in membrane preparations from Clostridium butyricum ATCC 19398. A particulate fraction was shown to catalyze the formation of phosphatidylethanolamine and plasmenylethanolamine when vesicles containing phosphatidylserine and plasmenylserine were used as s... | ['Carboxy-Lyases', 'Chromatography, Thin Layer', 'Clostridium', 'Decarboxylation', 'Detergents', 'Phosphatidylserines', 'Plasmalogens', 'Protoplasts'] | 4,020,299 | [['D08.811.520.224.125'], ['E05.196.181.400.537'], ['B03.300.390.400.200', 'B03.353.625.375.500', 'B03.510.415.400.200'], ['G02.111.195', 'G02.607.188', 'G03.225'], ['D27.720.877.265', 'J01.516.381'], ['D10.570.755.375.760.400.971'], ['D10.570.755.375.760.400.985.820'], ['A11.789']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Freeze-fracture electron microscopic observations on the effects of sulphydryl group reagents on human erythrocyte membranes. | Freeze-fracture electron microscopy of human red blood cells at pH 7.4 and 5.5 reveals the presence of membrane elevations (50-100 nm diameter). These are also observed after incubation of the erythrocytes with N-ethylmaleimide but not after incubation with p-chloromercuribenzene sulphonate. Neither of the sulphydryl-g... | ['Erythrocyte Membrane', 'Freeze Fracturing', 'Humans', 'Microscopy, Electron', 'Sulfhydryl Reagents'] | 3,677,180 | [['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['E01.370.225.500.620.620.260', 'E01.370.225.750.600.620.260', 'E05.200.500.620.620.260', 'E05.200.750.600.620.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['D27.720.470.410.700']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression and function of integrin alpha4beta1 and vascular cell adhesion molecule-1 (VCAM-1) during sympathetic innervation of the heart. | The interaction between the integrin alpha4beta1 receptor on superior cervical ganglion (SCG) neurons and vascular cell adhesion molecule-1 (VCAM-1) in cardiac tissue has been implicated in proper development of the sympathetic innervation of the heart (Wingerd et al. [2002] J Neurosci 22:10772-10780). In this study, w... | ['Animals', 'Cells, Cultured', 'Heart', 'Immunohistochemistry', 'Integrin alpha4beta1', 'Neurons', 'Rats', 'Superior Cervical Ganglion', 'Vascular Cell Adhesion Molecule-1'] | 15,366,013 | [['B01.050'], ['A11.251'], ['A07.541'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['D12.776.395.550.200.625.347', 'D12.776.543... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Antiviral effect of bacterially produced human interferon (Hu-IFN alpha 2) against experimental vaccinia infection in calves. | The heterologous antiviral efficiency of bacterially produced human interferon (Hu-IFN alpha 2) in the bovine species was studied, using vaccinia infection as experimental model. In a double blind experiment, young calves were intramuscularly injected daily for seven consecutive days with different doses of Hu-IFN alph... | ['Animals', 'Antibodies, Viral', 'Cattle', 'DNA, Recombinant', 'Humans', 'Interferon Type I', 'Metabolic Clearance Rate', 'Vaccinia', 'Vaccinia virus', 'Viral Interference'] | 3,989,335 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['E01.370.225.843', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heterozygote deficiency, population substructure and their implications in DNA fingerprinting. | Substructured populations exhibit an overall deficiency of heterozygosity whose proportional magnitude depends on the nature of substructuring, i.e., the number of subpopulations (s), their time of divergence (t) from the ancestral population, and the rate of gene flow amongst them (m). Since apparent heterozygote defi... | ['African Continental Ancestry Group', 'DNA Fingerprinting', 'European Continental Ancestry Group', 'Genetics, Population', 'Heterozygote', 'Humans', 'Repetitive Sequences, Nucleic Acid'] | 1,733,828 | [['M01.686.508.100'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['M01.686.508.400'], ['H01.158.273.343.335'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.708', 'G05.360.080.708']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Impaired time perception and motor timing in stimulant-dependent subjects. | Stimulant-dependent individuals (SDI) have abnormal brain metabolism and structural changes involving dopaminergic target areas important for the processing of time. These individuals are also more impulsive and impaired in working memory and attention. The current study tested whether SDI show altered temporal process... | ['Adult', 'Attention', 'Cocaine', 'Cognition Disorders', 'Dopamine', 'Humans', 'Impulsive Behavior', 'Male', 'Memory, Short-Term', 'Methamphetamine', 'Middle Aged', 'Neuropsychological Tests', 'Perceptual Disorders', 'Prefrontal Cortex', 'Psychomotor Performance', 'Severity of Illness Index', 'Substance-Related Disorde... | 17,434,690 | [['M01.060.116'], ['F02.830.104.214'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['F03.615.250'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.527'], ['F02.463.425.540.407'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Binding effect of Cu(2+) as a trigger on the sol-to-gel and the coil-to-helix transition processes of polysaccharide, gellan gum. | The binding effect of divalent cation Cu(2+) on the gelation process with a coil-helix transition in Cu(2+)/gellan aqueous solutions has been successfully elucidated by EPR, CD, and viscoelasticity measurements. Generally, Na-type gellan gum in aqueous solution can make gel when accompanied by an intrinsic coil-helix f... | ['Binding Sites', 'Circular Dichroism', 'Copper', 'Elasticity', 'Gels', 'Molecular Conformation', 'Polysaccharides, Bacterial', 'Viscosity'] | 15,132,674 | [['G02.111.570.120'], ['E05.196.867.151'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G01.374.590'], ['D20.280.320', 'D26.255.165.320'], ['G02.111.570.820'], ['D09.698.718', 'D23.050.161.616'], ['G02.930']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of the plasmid-borne quinolone resistance gene qnrB19 in Salmonella enterica serovar Typhimurium. | A qnrB19 gene variant, carried by an IncL/M-like plasmid, was detected in a multidrug Salmonella enterica serovar Typhimurium human strain with reduced susceptibility to ciprofloxacin. The genetic environment around the gene was fully sequenced (20 kb). A large gene cluster, containing the aph, qnrB19, and blaSHV-12-li... | ['Anti-Bacterial Agents', 'Bacterial Proteins', 'DNA Transposable Elements', 'Drug Resistance, Multiple, Bacterial', 'Evolution, Molecular', 'Microbial Sensitivity Tests', 'Multigene Family', 'Plasmids', 'Quinolones', 'Salmonella typhimurium'] | 19,528,272 | [['D27.505.954.122.085'], ['D12.776.097'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['G05.045.250', 'G16.075.250'], ['E01.370.225.875.595', 'E05.200.875.595'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Auditory temporal perceptual learning and transfer in Chinese-speaking children with developmental dyslexia. | Perceptual learning refers to the improvement of perceptual performance as a function of training. Recent studies found that auditory perceptual learning may improve phonological skills in individuals with developmental dyslexia in alphabetic writing system. However, whether auditory perceptual learning could also bene... | ['Auditory Perception', 'Child', 'Dyslexia', 'Education of Intellectually Disabled', 'Female', 'Handwriting', 'Humans', 'Learning', 'Male', 'Reading', 'Speech Articulation Tests', 'Teaching', 'Transfer, Psychology'] | 29,413,429 | [['F02.463.593.071', 'G07.888.125'], ['M01.060.406'], ['C10.597.606.150.500.300', 'C10.597.606.150.550.200', 'C23.888.592.604.150.500.300', 'C23.888.592.604.150.550.200', 'F03.625.562.400'], ['F02.784.629.375', 'I02.233.213.400'], ['L01.559.423.906.539'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425',... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Expression of the human NRAMP1 gene in professional primary phagocytes: studies in blood cells and in HL-60 promyelocytic leukemia. | In the mouse, mutations at the natural resistance-associated macrophage protein 1 (Nramp1) gene abrogate resistance to infection with antigenically unrelated intracellular parasites such as Mycobacterium, Salmonella, and Leishmania. Nramp1 expression is restricted to reticuloendothelial organs and peripheral blood leuk... | ['Base Sequence', 'Carrier Proteins', 'Cation Transport Proteins', 'HL-60 Cells', 'Humans', 'Jurkat Cells', 'Membrane Proteins', 'Molecular Sequence Data', 'Neutrophils', 'RNA, Messenger', 'Sequence Alignment', 'Species Specificity', 'Tumor Cells, Cultured'] | 9,000,542 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
No Relation between Body Temperature and Arterial Recanalization at Three Days in Patients with Acute Ischaemic Stroke. | BACKGROUND: Recanalization of an occluded intracranial artery is influenced by temperature-dependent enzymes, including alteplase. We assessed the relation between body temperature on admission and recanalization.METHODS: We included 278 patients with acute ischaemic stroke within nine hours after symptom onset, who ha... | ['Aged', 'Body Temperature', 'Brain Ischemia', 'Cerebrovascular Circulation', 'Female', 'Humans', 'Male', 'Stroke', 'Time Factors', 'Tissue Plasminogen Activator'] | 26,473,959 | [['M01.060.116.100'], ['E01.370.600.875.374', 'G07.110'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.775', 'C14.907.253.855'], ['G01.910.857'], ['D08.811.277.656.300.760.875', 'D08.811.277.656.959.350.875', 'D12.776.124.125.662.768... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sub- or intertrochanteric fracture following screw fixation of an intracapsular proximal femoral fracture: true complication or technical error? | PURPOSE: To review, retrospectively, the possible causes of sub- or intertrochanteric fractures after screw fixation of intracapsular fractures of the proximal femur.METHODS: Eighty-four patients with an intracapsular fracture of proximal femur were operated between 1995 and 1998 by using three cannulated 6.25 mm screw... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomechanical Phenomena', 'Bone Screws', 'Female', 'Femur Neck', 'Fracture Fixation, Internal', 'Hip Fractures', 'Humans', 'Joint Capsule', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiography', 'Recurrence', 'Reoperation', 'Retrospective Studies', 'Risk Factors', '... | 12,723,288 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G01.154.090', 'G01.374.089'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['A02.835.232.043.150.510'], ['E04.555.300.300'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro susceptibility of fungi to killing by neutrophil granulocytes discriminates between primary pathogenicity and opportunism. | Pathogenic fungi, according to their propensity to cause infection of apparently normal individuals, can be grouped into either primary pathogens (e.g., Coccidioides, Histoplasma, Paracoccidioides, Blastomyces, and Sporothrix) or opportunists (e.g., Candida, Mucoraceae, Aspergillus spp., Petriellidium, and Trichosporon... | ['Blastomycosis', 'Candidiasis', 'Disease Susceptibility', 'Fungi', 'Histoplasmosis', 'Humans', 'Hydrogen Peroxide', 'Mycoses', 'Neutrophils', 'Oxygen Consumption', 'Paracoccidioidomycosis', 'Phagocytosis', 'Virulence'] | 3,734,102 | [['C01.150.703.302.055', 'C01.150.703.534.350', 'C01.748.435.395', 'C01.800.200.055', 'C08.381.472.350', 'C08.730.435.395', 'C17.800.838.208.055'], ['C01.150.703.160'], ['C23.550.291.687', 'G07.100.250'], ['B01.300'], ['C01.150.703.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', ... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An optimized framework for quantitative magnetization transfer imaging of the cervical spinal cord in vivo. | PURPOSE: To develop a framework to fully characterize quantitative magnetization transfer indices in the human cervical cord in vivo within a clinically feasible time.METHODS: A dedicated spinal cord imaging protocol for quantitative magnetization transfer was developed using a reduced field-of-view approach with echo ... | ['Adult', 'Algorithms', 'Cervical Cord', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Myelin Sheath', 'Signal Processing, Computer-Assisted'] | 28,921,614 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['A08.186.854.126'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.800.690.500', 'A10.755.503', 'A11.284.149... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Puerarin prevents inflammation and apoptosis in the neurocytes of a murine Parkinson's disease model. | The aim of this study was to investigate Parkinson's disease (PD) using a murine model of PD. Specifically, we aimed to explore the mechanism by which puerarin prevents inflammation and apoptosis in neurocytes. Eighty healthy male C57/BL6 mice were randomly selected and divided into four groups (N = 20 each): control g... | ['1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine', 'Animals', 'Apoptosis', 'Caspase 3', 'Disease Models, Animal', 'Down-Regulation', 'Glial Fibrillary Acidic Protein', 'Inflammation', 'Isoflavones', 'Male', 'Mice, Inbred C57BL', 'Neurons', 'Nitric Oxide Synthase Type II', 'Parkinson Disease', 'Substantia Nigra', 'Tyrosin... | 27,808,353 | [['D03.383.725.450'], ['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D05.750.078.593.400', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Salmonellosis in Poland in 2011. | THE PURPOSE OF THE STUDY: To assess the epidemiological situation of salmonellosis in Poland in 2011 as compared with previous years.MATERIALS AND METHODS: The assessment was based on the results of analysis of the data from the newsletter "Infectious diseases and poisonings in Poland 2011", information from laboratori... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Disease Outbreaks', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Intestinal Diseases', 'Male', 'Middle Aged', 'Poland', 'Salmonella Food Poisoning', 'Young Adult'] | 24,340,562 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['M0... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Proteasomes associated with the Blm10 activator protein antagonize mitochondrial fission through degradation of the fission protein Dnm1. | The conserved Blm10/PA200 activators bind to the proteasome core particle gate and facilitate turnover of peptides and unfolded proteins in vitro. We report here that Blm10 is required for the maintenance of functional mitochondria. BLM10 expression is induced 25-fold upon a switch from fermentation to oxidative metabo... | ['Apoptosis', 'Base Sequence', 'DNA Primers', 'GTP Phosphohydrolases', 'Mitochondria', 'Mitochondrial Proteins', 'Oxidative Stress', 'Proteasome Endopeptidase Complex', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 24,604,417 | [['G04.146.954.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D08.811.277.040.330'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D12.776.575'], ['G03.673', 'G07.775.750'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Low-dose antithymocyte globulin enhanced the efficacy of tacrolimus and mycophenolate for GVHD prophylaxis in recipients of unrelated SCT. | We performed a retrospective analysis of the outcome of 197 consecutive unrelated donor transplant recipients who received GVHD prophylaxis either TM regimen (tacrolimus and mycophenolate) (121 patients) or TM/ATG-G regimen (TM with low-dose antithymocyte globulin (ATG) of 4.5 mg/kg, ATG-G, Genzyme) (76 patients). Cumu... | ['Adult', 'Aged', 'Antilymphocyte Serum', 'Female', 'Follow-Up Studies', 'Graft vs Host Disease', 'Hematologic Neoplasms', 'Humans', 'Immunosuppressive Agents', 'Male', 'Middle Aged', 'Mycophenolic Acid', 'Risk Factors', 'Stem Cell Transplantation', 'Tacrolimus', 'Unrelated Donors'] | 25,285,804 | [['M01.060.116'], ['M01.060.116.100'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C20.452'], ['C04.588.448', 'C15.378... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Support media can steer methanogenesis in the presence of phenol through biotic and abiotic effects. | A wide variety of inhibitors can induce anaerobic digester disruption. To avoid performance losses, support media can be used to mitigate inhibitions. However, distinguishing the physico-chemical from the biological mechanisms of such strategies remains delicate. In this framework, the impact of 10 g/L of different ty... | ['Anaerobiosis', 'Archaea', 'Bacteria', 'Bioreactors', 'Culture Media', 'Methane', 'Methanosarcina', 'Microbial Consortia', 'Phenols', 'Waste Management', 'Zeolites'] | 29,684,699 | [['G02.111.062', 'G03.078'], ['B02'], ['B03'], ['E07.115', 'J01.897.120.115'], ['D27.720.470.305', 'E07.206'], ['D02.455.326.146.571'], ['B02.200.765.550.550'], ['G06.591.750', 'G16.500.275.157.049.100.500.750', 'N06.230.124.049.100.500.500'], ['D02.455.426.559.389.657'], ['N06.850.780.200.800.800.900', 'N06.850.860.51... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Moderate wine consumption and prevention of coronary heart disease]. | Moderate alcohol consumption and in particular wine consumption, is associated with a significant reduction in cardiovascular morbidity and mortality in epidemiological studies. Although no randomized placebo-controlled studies with wine intervention exist - and will probably never exist - the observed association can ... | ['Coronary Artery Disease', 'Ethanol', 'Evidence-Based Medicine', 'Humans', 'Wine'] | 24,343,181 | [['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['D02.033.375'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02.200.100.900', 'J02.350.887']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Hairpins create minute inversions in non-coding regions of chloroplast DNA. | Minute inversions (4 bp in length), associated with probable hairpin secondary structures, were inferred from comparative analysis of rpl16 intron sequences from the chloroplast genomes of Chusquea species and related bamboos (Poaceae). The inverted sequences, which appear to have arisen independently on several occasi... | ['Base Sequence', 'Chloroplasts', 'Chromosome Inversion', 'DNA, Plant', 'Exons', 'Genes, Plant', 'Introns', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Phylogeny', 'Plants', 'Polymorphism, Genetic'] | 8,753,656 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.430.214.190.875.700.140'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['D13.444.308.435'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.024.220.400', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of the Asp175Asn and Glu180Gly TPM1 mutations on actin-myosin interaction during the ATPase cycle. | Hypertrophic cardiomyopathy (HCM), characterized by cardiac hypertrophy and contractile dysfunction, is a major cause of heart failure. HCM can result from mutations in the gene encoding cardiac á-tropomyosin (TM). To understand how the HCM-causing Asp175Asn and Glu180Gly mutations in á-tropomyosin affect on actin-myos... | ['Actins', 'Actomyosin', 'Adenosine Triphosphatases', 'Amino Acid Substitution', 'Animals', 'Asparagine', 'Aspartic Acid', 'Cardiomyopathy, Hypertrophic', 'Fluorescent Dyes', 'Glutamic Acid', 'Glycine', 'Humans', 'Muscle Contraction', 'Mutation', 'Myosin Subfragments', 'Naphthalenesulfonates', 'Peptide Fragments', 'Pro... | 22,155,441 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D12.776.210.500.154'], ['D08.811.277.040.025'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['C14.280.238.100', 'C14.28... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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