Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Commercial versus technical cues to position a new product: Do hedonic and functional/healthy packages differ? | Packaging attributes can be classified into two main blocks: visual/commercial attributes and informational/technical ones. In this framework, our objectives are: (i) to compare if both kinds of attributes lead to equal responses (consumers' attitudes improvement and product trial) and (ii) to compare if they work equa... | ['Color', 'Consumer Behavior', 'Consumer Health Information', 'Cues', 'Female', 'Food', 'Humans', 'Intention', 'Male', 'Perception', 'Product Packaging', 'Young Adult'] | 29,289,931 | [['G01.590.540.199'], ['F01.145.236'], ['I02.233.332.186', 'N02.421.726.407.229'], ['F02.463.425.234'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['F02.463.593'], ['J01.576.761'], ['M01.060.116.815']] | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Surgical office-based ultrasound of the breast. | How surgical office-based ultrasound (US) influences the management of nonpalpable, new or increasing size, mammogram-detected breast masses was evaluated. Ninety-seven patients had diagnostic US only; of these, 67 had their mass diagnosed as a simple cyst, and 30 had a negative US. Fifty-three additional patients unde... | ['Biopsy, Needle', 'Breast Diseases', 'Breast Neoplasms', 'Carcinoma', 'Choristoma', 'Diagnosis, Differential', 'Female', 'Fibroadenoma', 'Fibrocystic Breast Disease', 'Follow-Up Studies', 'General Surgery', 'Humans', 'Hyperplasia', 'Lymph Nodes', 'Mammography', 'Papilloma', "Physicians' Offices", 'Retrospective Studie... | 7,793,744 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C17.800.090'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['C23.300.250'], ['E01.171'], ['C04.557.450.565.590.595.350... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts. | The efficacy of most cancer treatments is strongly influenced by the tumor blood supply. The results of experimental studies using xenografted tumors to evaluate novel cancer treatments may therefore vary considerably depending on the blood supply of the specific tumor model being used. Mechanisms underlying intertumor... | ['Animals', 'Cell Line, Tumor', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Green Fluorescent Proteins', 'Humans', 'Image Processing, Computer-Assisted', 'Melanoma', 'Mice', 'Mice, Inbred BALB C', 'Microcirculation', 'Neoplasm Transplantation', 'Neovascularization, Pathologic', 'Po... | 23,149,341 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.393.332'], ['G05.308.370'], ['D12.776.532.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rational management of peptic ulcer disease. | If the goal of treatment is healing of the ulcer, then success is usually achieved - repeatedly. In order to avoid recurring episodes, it is essential that both the physician and the patient learn to regard the ulcer as the result of a chronic disease process. This means that management becomes a lifelong undertaking, ... | ['Antacids', 'Humans', 'Hypnotics and Sedatives', 'Parasympatholytics', 'Peptic Ulcer', 'Time Factors'] | 1,026,631 | [['D27.505.519.170', 'D27.505.954.483.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['D27.505.696.663.050.650'], ['C06.405.469.275.800', 'C06.405.748.586'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Safe from harm: learned, instructed, and symbolic generalization pathways of human threat-avoidance. | Avoidance of threatening or unpleasant events is usually an adaptive behavioural strategy. Sometimes, however, avoidance can become chronic and lead to impaired daily functioning. Excessive threat-avoidance is a central diagnostic feature of anxiety disorders, yet little is known about whether avoidance acquired in the... | ['Adaptation, Psychological', 'Adult', 'Anxiety Disorders', 'Conditioning, Classical', 'Conditioning, Psychological', 'Fear', 'Female', 'Generalization, Psychological', 'Humans', 'Learning', 'Male'] | 23,077,631 | [['F01.058'], ['M01.060.116'], ['F03.080'], ['F02.463.425.179.308'], ['F02.463.425.179'], ['F01.470.361'], ['F02.463.425.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Light microscopic Golgi study of mitral/tufted cells in the accessory olfactory bulb of the adult rat. | Mitral/tufted cells (MTCs) of the accessory olfactory bulb (AOB) of adult rats were investigated light microscopically with the rapid Golgi method. The somata of the MTCs, appearing ovoid or triangular in shape, are distributed throughout the external plexiform layer. The soma size varies from small to large (12-26 mic... | ['Animals', 'Dendrites', 'Golgi Apparatus', 'Nerve Fibers, Myelinated', 'Olfactory Bulb', 'Rats', 'Rats, Inbred Strains', 'Species Specificity', 'Staining and Labeling', 'Ultrasonography'] | 1,719,045 | [['B01.050'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['A11.284.430.214.190.875.336'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.514'], ['A08.186.211.200.885.388'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G16.824'], ['E0... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Consulting rates of general practitioners by demographic groups in a defined community. | The demographic characteristics were recorded of 4798 patients aged from 15 to 69 years who consulted, for any reason, the general practitioners of 97% of the practices in the Perth Statistical Division on one day in 1971. A consulting rate in terms of the population at risk was calculated for patients of different sex... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Australia', 'Employment', 'Ethnic Groups', 'Family Characteristics', 'Family Practice', 'Female', 'Health Services', 'Humans', 'Male', 'Middle Aged', 'Sex Factors'] | 661,710 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['N01.824.245'], ['M01.686.754', 'N01.224.317'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['H02.403.340.500'], ['N02.... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The effect of tropical flours (breadfruit and banana) on structural and technological properties of beef emulsion modeling systems. | This study evaluated structural and technological properties of beef emulsion modeling systems prepared with tropical flours. Treatments consisted of a control (0% flour inclusion) and three inclusion levels (1%, 2% and 4%) of two breadfruit flours and a banana flour. Flour type affected starch content of cooked beef e... | ['Animals', 'Artocarpus', 'Cattle', 'Emulsions', 'Food Handling', 'Meat Products', 'Musa', 'Soybean Proteins', 'Starch'] | 32,050,113 | [['B01.050'], ['B01.650.940.800.575.912.250.859.937.406.088'], ['B01.050.150.900.649.313.500.380.271'], ['D20.280.260', 'D26.255.165.260'], ['J01.576.423.200'], ['G07.203.300.600.500', 'J02.500.600.500'], ['B01.650.940.800.575.912.250.618.937.555.500'], ['D12.776.765.741', 'G07.203.300.428.920.750', 'G07.203.300.850.45... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Point-of-Care Ultrasonography to Assess Portal Vein Pulsatility and the Effect of Inhaled Milrinone and Epoprostenol in Severe Right Ventricular Failure: A Report of 2 Cases. | This article describes 2 patients with severe acute right ventricular failure causing circulatory shock. Portal vein pulsatility assessed by bedside ultrasonography suggested clinically relevant venous congestion. Management included cardiac preload reduction and combined inhalation of milrinone and epoprostenol to red... | ['Administration, Inhalation', 'Aged, 80 and over', 'Epoprostenol', 'Female', 'Heart Failure', 'Heart Ventricles', 'Humans', 'Middle Aged', 'Milrinone', 'Point-of-Care Systems', 'Portal Vein', 'Ultrasonography'] | 28,604,468 | [['E02.319.267.050'], ['M01.060.116.100.080'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['C14.280.434'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.092.080.085.543', 'D03.383.725.050.085.543'], ['N04.452.442.452.452.680', 'N04.452.515.360.652', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Measuring spatial variation in secondary production and food quality using a common consumer approach in Lake Erie. | Lake Erie is a large lake straddling the border of the USA and Canada that has become increasingly eutrophic in recent years. Eutrophication is particularly focused in the shallow western basin. The western basin of Lake Erie is hydrodynamically similar to a large estuary, with riverine inputs from the Detroit and Maum... | ['Animals', 'Bivalvia', 'Cyanobacteria', 'Ecosystem', 'Fatty Acids', 'Great Lakes Region', 'Lakes', 'Lipids', 'Rivers', 'Time Factors'] | 27,411,257 | [['B01.050'], ['B01.050.500.644.080'], ['B03.280', 'B03.440.475.100'], ['G16.500.275.157', 'N06.230.124'], ['D10.251'], ['Z01.107.567.875.350'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D10'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Peripheral nerves disorders under exposure to metallic mercury and complex of toxic chemicals]. | Examination of patients with chronic mercury poisoning and fire men subjected to complex of toxic chemicals during fire extinguishing revealed subclinical latent disorder of peripheral nerves due to chronic mercury intoxication and clinical manifestations of polyneuropathy involving nerves of upper and lower limbs in f... | ['Air Pollutants, Occupational', 'Arm', 'Electromyography', 'Female', 'Fires', 'Humans', 'Leg', 'Lipid Peroxidation', 'Male', 'Mercury Poisoning', 'Occupational Diseases', 'Occupational Exposure', 'Polyneuropathies', 'Risk Factors'] | 16,430,119 | [['D27.888.284.101.268'], ['A01.378.800.075'], ['E01.370.405.255', 'E01.370.530.255'], ['N06.230.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['G02.111.515', 'G03.295.531.587'], ['C25.723.522.875'], ['C24'], ['N06.850.460.350.600'], ['C10.668.829.800'], ['E05.318.740.600.800.725', 'N05.7... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma. | The role of B-cell receptor (BCR)-mediated survival signals in diffuse large B-cell lymphoma (DLBCL) remains undefined. Ligand-induced BCR signaling induces receptor oligomerization, Igalpha/beta immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation, and activation of the spleen tyrosine kinase (SYK), w... | ['Apoptosis', 'Cell Culture Techniques', 'Cell Division', 'Cell Line, Tumor', 'Enzyme Inhibitors', 'Flow Cytometry', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Lymphoma, Large B-Cell, Diffuse', 'Oxazines', 'Protein-Tyrosine Kinases', 'Pyridines', 'Receptors, Antigen, B-Cell', 'Syk Kinase', 'Transcripti... | 18,006,696 | [['G04.146.954.035'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D27.505.519.389'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350',... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a tetrameric streptavidin mutein with reversible biotin binding capability: engineering a mobile loop as an exit door for biotin. | A novel form of tetrameric streptavidin has been engineered to have reversible biotin binding capability. In wild-type streptavidin, loop(3-4) functions as a lid for the entry and exit of biotin. When biotin is bound, interactions between biotin and key residues in loop(3-4) keep this lid in the closed state. In the en... | ['Amino Acid Motifs', 'Amino Acid Substitution', 'Bacterial Proteins', 'Binding Sites', 'Biotin', 'Chromatography, Affinity', 'Crystallography, X-Ray', 'Cystine', 'Kinetics', 'Models, Molecular', 'Protein Binding', 'Protein Engineering', 'Protein Interaction Domains and Motifs', 'Protein Structure, Quaternary', 'Recomb... | 22,536,357 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['E05.393.420.601.035', 'G05.558.109'], ['D12.776.097'], ['G02.111.570.120'], ['D03.383.129.308.080', 'D08.211.096'], ['E05.196.181.400.170'], ['E05.196.309.742.225'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental regulation of Pseudomonas aeruginosa PAO1 Las and Rhl quorum-sensing systems. | The lasI-lasR and the rhlI-rhlR quorum-sensing systems in Pseudomonas aeruginosa regulate the expression of numerous cellular and secreted virulence factor genes and play important roles in the development of biofilms. The las and rhl systems themselves are known to be directly or indirectly regulated by a number of tr... | ['4-Butyrolactone', 'Bacterial Proteins', 'Cluster Analysis', 'Colony Count, Microbial', 'DNA-Binding Proteins', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'Gene Expression Regulation, Developmental', 'Humans', 'Iron', 'Pseudomonas aeruginosa', 'Quorum Sensing', 'Sodium Chloride', 'Sputum', '... | 17,449,617 | [['D02.540.150', 'D03.383.312.150'], ['D12.776.097'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D12.776.260'], ['E05.393.332'], ['G05.308.300'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Youth risk behavior survey: the Alaskan perspective. | The Youth Risk Behavior Survey (YRBS) is a national school-based survey used to monitor health risk behaviors that contribute to the leading causes of mortality, morbidity, and social problems among youth and adults in the United States. Both high school and middle school surveys were administered to a representative g... | ['Adolescent', 'Adolescent Behavior', 'Age Distribution', 'Alaska', 'Child', 'Female', 'Health Surveys', 'Humans', 'Male', 'Risk-Taking', 'Sex Distribution'] | 10,093,358 | [['M01.060.057'], ['F01.145.022'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['Z01.107.567.875.580.100'], ['M01.060.406'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.722'], ['I01.240.800', 'N01.224.803', 'N06.850... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Cushing's syndrome during HIV treatment: pharmacological interaction during use of ritonavir]. | Physicians are not always aware that locally administered glucocorticoids can cause systemic toxicity. This risk is greatly enhanced in the case of pharmacological interactions. We present two cases of HIV-infected patients who developed Cushing-like symptoms as a result of a pharmacological interaction. Their antiretr... | ['Adult', 'Albuterol', 'Androstadienes', 'Asthma', 'Bronchodilator Agents', 'Cushing Syndrome', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 CYP3A Inhibitors', 'Drug Combinations', 'Drug Interactions', 'Fluticasone-Salmeterol Drug Combination', 'Glucocorticoids', 'HIV Infections', 'HIV Protease Inhibitors', 'Humans', 'M... | 23,548,184 | [['M01.060.116'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['D04.210.500.054.079.129'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['C19.053.800.367'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Test-retest reliability and practice effects of executive function tasks in preschool children. | This study examined the test-retest reliability of executive function tasks in preschool children. Measures of working memory, response inhibition, attentional flexibility, and planning were administered to thirty three preschool children between the ages of 36 and 72 months (M = 54.75 months) on two testing occasions ... | ['Attention', 'Child, Preschool', 'Executive Function', 'Female', 'Humans', 'Inhibition, Psychological', 'Male', 'Memory, Short-Term', 'Neuropsychological Tests', 'Practice, Psychological', 'Problem Solving', 'Psychometrics', 'Reproducibility of Results'] | 22,256,888 | [['F02.830.104.214'], ['M01.060.406.448'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F02.463.425.540.407'], ['F04.711.513'], ['F02.463.425.674'], ['F02.463.425.725', 'F02.463.785.810'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', '... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of bypass grafting to the infarct artery on late potentials in coronary operations. | BACKGROUND: Late potentials (LPs) after myocardial infarction identify the risk of arrhythmic events and sudden death, and the absence of anterograde flow in the infarct-causing occluded coronary artery frequently is associated with LPs on signal-averaged electrocardiography. The present study was designed to clarify t... | ['Aged', 'Coronary Artery Bypass', 'Electrocardiography', 'Female', 'Heart Conduction System', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Time Factors', 'Ventricular Function, Left'] | 7,646,107 | [['M01.060.116.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['G01.910.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Longitudinal study of the long-term relation between physical activity and obesity in adults. | BACKGROUND: Earlier observational studies of the relation between physical activity and obesity are inconsistent and ambiguous, showing a clear cross-sectional inverse relation, and a prospective association only when physical activity at the time of follow-up is included.OBJECTIVE: To examine the long-term effect of l... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Cross-Sectional Studies', 'Exercise', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Prospective Studies', 'Regression Analysis', 'Sex Factors'] | 14,647,181 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.410.698.277', 'I03.350'], ['B01.0... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Role of virulence factors in resistance of avian pathogenic Escherichia coli to serum and in pathogenicity. | In chickens, colibacillosis is caused by avian pathogenic Escherichia coli (APEC) via respiratory tract infection. Many virulence factors, including type 1 (F1A) and P (F11) fimbriae, curli, aerobactin, K1 capsule, and temperature-sensitive hemagglutinin (Tsh) and plasmid DNA regions have been associated with APEC. A s... | ['Animals', 'Bacterial Capsules', 'Blood Bactericidal Activity', 'Chickens', 'Escherichia coli', 'Escherichia coli Infections', 'Escherichia coli Proteins', 'Lipopolysaccharides', 'Mutation', 'Poultry Diseases', 'Virulence', 'Virulence Factors'] | 12,496,207 | [['B01.050'], ['A20.186'], ['G09.188.100', 'G12.450.564.204'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['D12.776.097.275'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.5... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oxygen derived free radicals and the course of Eimeria vermiformis infection in inbred strains of mice. | Free radical generation by peritoneal leukocytes from BALB/c and C57BL/6 mice was monitored for 18 days following infection with Eimeria vermiformis. Free radical generation occurred earlier and was quantitatively much greater in resistant BALB/c mice than in susceptible C57BL/6 mice, resistance being indicated by a mu... | ['Animals', 'Coccidiosis', 'Disease Susceptibility', 'Female', 'Free Radicals', 'Leukocyte Count', 'Leukocytes', 'Luminol', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Oxygen', 'Parasite Egg Count', 'Peritoneal Cavity', 'Random Allocation', 'Species Specificity'] | 2,084,608 | [['B01.050'], ['C01.610.752.250'], ['C23.550.291.687', 'G07.100.250'], ['D01.339', 'D02.389'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105.595'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['D... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Actions of peptides isolated from amphibian skin on pancreatic acinar cells. | In dispersed acinar cells prepared from guinea pig pancreas, peptides isolated from amphibian skin (caerulein, bombesin, litorin, and physalaemin) as well as eledoisin, a peptide isolated from the posterior salivary gland of a Mediterranean octopod, increased outflux of 45Ca, release of bound 45Ca, accumulation of cycl... | ['Amylases', 'Animals', 'Anura', 'Biological Transport, Active', 'Bombesin', 'Calcium', 'Ceruletide', 'Cyclic AMP', 'Cyclic GMP', 'Eledoisin', 'Guinea Pigs', 'Oligopeptides', 'Pancreas', 'Physalaemin', 'Proteins'] | 210,673 | [['D08.811.277.450.066'], ['B01.050'], ['B01.050.150.900.090.180'], ['G03.143.310'], ['D06.472.699.100', 'D12.644.400.085', 'D12.644.548.100', 'D12.776.631.650.085', 'D20.888.033.137', 'D23.946.833.033.137'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.644.456.241'], ['D03.633.100.759.646.138.395', 'D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epitope mapping of recombinant antigens by transposon mutagenesis. | We describe a method for generating a plasmid library expressing random truncations of a recombinant protein and for epitope mapping by screening the library with monoclonal antibodies. The key step is the random introduction of the transposon, Tn1000, which carries stop codons in all three reading frames, into a bacte... | ['Antibodies, Monoclonal', 'Antigens', 'Base Sequence', 'Blotting, Western', 'DNA Transposable Elements', 'Dystrophin', 'Epitope Mapping', 'Escherichia coli', 'Molecular Sequence Data', 'Mutagenesis', 'Recombinant Proteins', 'Sequence Analysis, DNA'] | 8,521,039 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Perceived sources of stress among dental students. | A survey of dental students' perceptions of stress indicates that academic factors and faculty relationships with students are the areas that create the most stress. Differences between the four classes in the ranking of several areas reflect the differences in academic and clinical requirements and experience associat... | ['Dental Care', 'Educational Measurement', 'Faculty, Dental', 'Female', 'Financial Management', 'Humans', 'Interpersonal Relations', 'Male', 'Motor Skills', 'Psychophysiologic Disorders', 'Stress, Psychological', 'Students, Dental'] | 6,929,835 | [['E06.170', 'N02.421.240.190'], ['I02.399'], ['M01.526.485.360', 'M01.526.702.250.273', 'N02.360.360'], ['N03.219.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.808.260'], ['C23.888.592.700'], ['F01.145.126.990', 'F02.830.900'], ['M01.848.769.519']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effect of serum sodium concentration and tolvaptan treatment on length of hospitalization in patients with heart failure. | PURPOSE: The effect of serum sodium concentration and tolvaptan treatment on length of stay (LOS) in patients hospitalized with heart failure (HF) was evaluated.METHODS: Data for this study were derived from a large, international, Phase III trial of patients hospitalized for HF. Two distinct post hoc analyses were per... | ['Adolescent', 'Adult', 'Antidiuretic Hormone Receptor Antagonists', 'Benzazepines', 'Cardiotonic Agents', 'Heart Failure', 'Humans', 'Hyponatremia', 'Length of Stay', 'Sodium', 'Tolvaptan'] | 21,289,328 | [['M01.060.057'], ['M01.060.116'], ['D27.505.519.174', 'D27.505.696.560.311'], ['D03.633.100.079'], ['D27.505.954.411.222', 'D27.720.799.080'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.620'], ['E02.760.400.480', 'N02.421.585.400.480'], ['D01.268.549.750', 'D01.268.557.650', 'D01.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of pancreatic status and sex on polyunsaturated fatty acid profiles in cystic fibrosis. | BACKGROUND: Some but not all studies have reported abnormal polyunsaturated fatty acid composition in cystic fibrosis (CF) patients. We investigated the influence of pancreatic status and sex on the fatty acid profile in plasma and erythrocyte membranes in patients with CF.METHODS: After a 1-step transesterification wi... | ['8,11,14-Eicosatrienoic Acid', 'Adolescent', 'Arachidonic Acid', 'Cystic Fibrosis', 'Docosahexaenoic Acids', 'Erythrocyte Membrane', 'Exocrine Pancreatic Insufficiency', 'Fatty Acids, Unsaturated', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Male', 'Plasma', 'Sex Factors'] | 18,089,657 | [['D10.251.355.255.207'], ['M01.060.057'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D10.212.302.380.410.210', 'D10.251.355.337.250', 'D10.627.430.450.375'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['C06.689.276'], ['D1... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Meeting the four-hour deadline in an A&E department. | PURPOSE: Accident and emergency (A&E) departments experience a secondary peak in patient length of stay (LoS) at around four hours, caused by the coping strategies used to meet the operational standards imposed by government. The aim of this paper is to build a discrete-event simulation model that captures the coping s... | ['Bed Occupancy', 'Computer Simulation', 'Emergency Service, Hospital', 'Humans', 'Length of Stay', 'London', 'Models, Organizational', 'Operations Research', 'State Medicine', 'Time and Motion Studies'] | 22,256,661 | [['N02.278.050'], ['L01.224.160'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['Z01.433.553', 'Z01.542.363.300.553'], ['E05.599.670', 'N04.452.534'], ['H01.770.644.333', 'L01.906.394'], ['N03.349... | ['Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
The cholinergic influence on the mesenteric ganglion affects the liberation of ovarian steroids and nitric oxide in oestrus day rats: characterization of an ex vivo system. | The axons that constitute the ovarian nervous plexus originate mostly in the principal neurons of the superior mesenteric ganglion (SMG) that is part of the sympathetic ganglionic chain and exhibits cholinergic receptors. In order to observe the effect of acetylcholine, the main neurotransmitter in the ganglionic trans... | ['Acetylcholine', 'Androstenedione', 'Animals', 'Cholinergic Agents', 'Dissection', 'Estradiol', 'Estrus', 'Female', 'Functional Laterality', 'Ganglia, Sympathetic', 'Gonadal Steroid Hormones', 'In Vitro Techniques', 'Models, Animal', 'Nitric Oxide', 'Nitrites', 'Ovary', 'Perfusion', 'Potassium Chloride', 'Progesterone... | 17,170,216 | [['D02.092.211.111'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['B01.050'], ['D27.505.519.625.120', 'D27.505.696.577.120'], ['E01.370.225.998.221', 'E04.221', 'E05.200.998.221'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison between electro-acupuncture and hydrotherapy, both in combination with patient education and patient education alone, on the symptomatic treatment of osteoarthritis of the hip. | OBJECTIVES: The aim of the study was to evaluate the therapeutic effect of electro-acupuncture (EA) and hydrotherapy, both in combination with patient education or with patient education alone, in the treatment of osteoarthritis in the hip.METHODS: Forty-five patients, aged 42-86 years, with radiographic changes consis... | ['Adult', 'Aged', 'Aged, 80 and over', 'Combined Modality Therapy', 'Disability Evaluation', 'Electroacupuncture', 'Female', 'Humans', 'Hydrotherapy', 'Male', 'Middle Aged', 'Osteoarthritis, Hip', 'Pain', 'Pain Management', 'Pain Measurement', 'Patient Education as Topic', 'Quality of Life', 'Time Factors', 'Treatment ... | 15,100,594 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.186'], ['E01.370.400'], ['E02.186.250', 'E02.190.044.244', 'E02.331.399', 'E02.779.468.399', 'E02.831.535.468.399', 'E03.091.823.500', 'E03.155.519'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.779.492', 'E02.831.535.492'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Sex differences in the toxicokinetics of inhaled solvent vaporsin humans 1. m-Xylene. | The aim of this study was to evaluate possible sex differences in the inhalation toxicokinetics of m-xylene vapor. Seventeen healthy volunteers (nine women and eight men) were exposed to m-xylene (200 mg/m3) and to clean air (control exposure) on different occasions during 2 h of light physical exercise (50 W). The cho... | ['Administration, Inhalation', 'Adult', 'Area Under Curve', 'Chromatography, High Pressure Liquid', 'Female', 'Humans', 'Inhalation Exposure', 'Male', 'Middle Aged', 'Models, Biological', 'Physical Exertion', 'Sex Factors', 'Solvents', 'Volatilization', 'Xylenes'] | 14,644,617 | [['E02.319.267.050'], ['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.112'], ['M01.060.116.630'], ['E05.599.395'], ['G11.427.683'], ['N05.715.350.675', 'N06.850.490.875'], ['D27.720... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Concomitant neuropeptide-producing endometrial carcinomas and ileal carcinoid tumors. | The concomitant occurrence of neuropeptide-reactive endometrial carcinoma and ileal carcinoid tumor represents an observation that has been unreported until now. We have seen two patients with this rare combination of tumors. The endometrial carcinomas in these cases manifested focal immunoreactivity for neuron-specifi... | ['Aged', 'Carcinoid Tumor', 'Female', 'Gastrins', 'Histocytochemistry', 'Humans', 'Ileal Neoplasms', 'Nerve Tissue Proteins', 'Substance P', 'Uterine Neoplasms'] | 2,420,166 | [['M01.060.116.100'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D12.776.631.650.320'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.1... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Administration of sirolimus affects vein graft neointima hyperplasia]. | OBJECTIVE: To investigate the effect of Sirolimus on vein graft neointima hyperplasia via oral administration compared with local delivery, and find out an effective and safe way to provide support for clinical application.METHODS: A rabbit external jugular vein-to-common carotid artery model was established. Twenty-fo... | ['Animals', 'Apoptosis', 'Carotid Artery, Common', 'Cell Proliferation', 'Coronary Restenosis', 'Graft Occlusion, Vascular', 'Hyperplasia', 'Immunohistochemistry', 'Immunosuppressive Agents', 'In Situ Nick-End Labeling', 'Jugular Veins', 'Male', 'Proliferating Cell Nuclear Antigen', 'Rabbits', 'Random Allocation', 'Sir... | 17,068,626 | [['B01.050'], ['G04.146.954.035'], ['A07.015.114.186.200'], ['G04.161.750', 'G07.345.249.410.750'], ['C14.280.647.250.285.200', 'C14.907.585.250.285.200'], ['C23.550.767.400'], ['C23.550.444'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Serum levels and differential expression of CD44 in childhood leukemia and malignant lymphoma: correlation with prognostic criteria and survival. | BACKGROUND: The CD44, a cell surface proteoglycan, participates in a variety of function including tumor dissemination and metastasis. However, there are no available data on the prognostic significance of CD44 expression of tumor tissue correlated with serum sCD44 level in childhood leukemias and lymphomas.METHODS: Se... | ['Adolescent', 'Burkitt Lymphoma', 'Child', 'Child, Preschool', 'Female', 'Hodgkin Disease', 'Humans', 'Hyaluronan Receptors', 'Infant', 'Male', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Prognosis'] | 11,472,578 | [['M01.060.057'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['M01.060.406'], ['M01.060.406.448'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.6... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antiidiotypic responses to immunization with anti-Leu 3a in human immunodeficiency virus-seropositive individuals. | Anti-idiotypic antibodies to anti-CD4 monoclonal antibodies (MAbs) have been reported to bind to the human immunodeficiency virus (HIV) envelope glycoprotein gp120. To establish whether HIV-infected patients can mount an anti-idiotypic response to murine MAb, four individuals with symptoms of AIDS-related complex (ARC)... | ['Adult', 'Antibodies, Anti-Idiotypic', 'Antibodies, Monoclonal', 'Antigens, Differentiation, T-Lymphocyte', 'CD4-Positive T-Lymphocytes', 'Chromatography, Affinity', 'Enzyme-Linked Immunosorbent Assay', 'Flow Cytometry', 'HIV Envelope Protein gp120', 'HIV Seropositivity', 'Humans', 'Immunoglobulin G', 'Immunoglobulin ... | 1,671,054 | [['M01.060.116'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.894', 'D23.101.100.894'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structure-based design of potent Bcl-2/Bcl-xL inhibitors with strong in vivo antitumor activity. | Bcl-2 and Bcl-xL are key apoptosis regulators and attractive cancer therapeutic targets. We have designed and optimized a class of small-molecule inhibitors of Bcl-2 and Bcl-xL containing a 4,5-diphenyl-1H-pyrrole-3-carboxylic acid core structure. A 1.4 ? resolution crystal structure of a lead compound, 12, complexed w... | ['Animals', 'Antineoplastic Agents', 'Apoptosis Regulatory Proteins', 'Cell Death', 'Cell Line, Tumor', 'Cell Proliferation', 'Crystallography, X-Ray', 'Drug Design', 'Drug Screening Assays, Antitumor', 'Fluorescence Polarization', 'Humans', 'Inhibitory Concentration 50', 'Mice', 'Mice, SCID', 'Models, Molecular', 'Mol... | 22,747,598 | [['B01.050'], ['D27.505.954.248'], ['D12.644.360.075', 'D12.776.476.075'], ['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['E05.196.309.742.225'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Isoflurane preconditioning protects human neuroblastoma SH-SY5Y cells against in vitro simulated ischemia-reperfusion through the activation of extracellular signal-regulated kinases pathway. | It has been reported that a prior exposure of isoflurane, a commonly used volatile anesthetic in clinical practice, reduces brain cell death after ischemia. This isoflurane preconditioning-induced neuroprotection has been shown in rat in vivo and in vitro brain ischemia models. To investigate the mechanisms of this pro... | ['Butadienes', 'Cell Hypoxia', 'Cell Line, Tumor', 'Cell Survival', 'DNA, Single-Stranded', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Extracellular Signal-Regulated MAP Kinases', 'Glucose', 'Humans', 'Hypoxia-Ischemia, Brain', 'Isoflurane', 'Neuroblastoma', 'Neuroprotective Agents', 'Nitriles', 'Proto-O... | 16,806,162 | [['D02.455.326.271.665.146.240'], ['G03.197.300', 'G04.270.300'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical changes in the gingiva as a result of at-home bleaching. | An investigative study was performed to evaluate changes in gingival health with the application of a 10% carbamide peroxide bleaching gel using exposure times of 2 and 7 hours (overnight). The presence or absence of gingival inflammation was recorded using the Loe and Silness Gingival Index at intervals over a 28-day ... | ['Adult', 'Analysis of Variance', 'Carbamide Peroxide', 'Dental Devices, Home Care', 'Drug Combinations', 'Female', 'Gels', 'Gingivitis', 'Humans', 'Male', 'Periodontal Index', 'Peroxides', 'Self Care', 'Time Factors', 'Tooth Bleaching', 'Urea'] | 8,620,374 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D01.248.497.158.685.750.318', 'D01.339.431.374.318', 'D01.650.550.750.300', 'D02.065.950.278', 'D02.389.338.154'], ['E06.186.250', 'E06.761.726.292', 'E07.222.250'], ['D26.310'], ['D20.280.320', 'D26.255.165.320'], ['C01.408', 'C07.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Models of neuropathic pain in the rat. | Peripheral nerve injury due to trauma, disease, and certain toxins sometimes produces abnormal (neuropathic) pain syndromes that are chronic and refractory to standard analgesics. Knowledge of the mechanisms that produce neuropathic pain and the ability to search for new drugs to control it have been greatly advanced b... | ['Animals', 'Disease Models, Animal', 'Hyperalgesia', 'Male', 'Neuralgia', 'Rats', 'Rats, Sprague-Dawley'] | 21,956,807 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.597.751.791.400', 'C23.888.592.763.770.400'], ['C10.668.829.600', 'C23.888.592.612.664'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Management of cerebral malperfusion in surgical repair of acute type A aortic dissection. | OBJECTIVES: Cerebral malperfusion for patients with acute type A aortic dissection (AAAD) remains an unsolved problem. The present study aimed to evaluate our management of cerebral perfusion and identify predictors of perioperative cerebral malperfusion in patients undergoing surgical repair of AAAD.METHODS: Between J... | ['Aged', 'Aneurysm, Dissecting', 'Aortic Aneurysm', 'Cerebrovascular Circulation', 'Female', 'Humans', 'Intracranial Thrombosis', 'Male', 'Middle Aged', 'Monitoring, Intraoperative', 'Postoperative Complications', 'Reperfusion', 'Risk Factors', 'Vascular Surgical Procedures'] | 28,369,452 | [['M01.060.116.100'], ['C14.907.055.050'], ['C14.907.055.239', 'C14.907.109.139'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.525.425', 'C14.907.253.566.350', 'C14.907.355.590.213.350'], ['M01.060.116.630'], ['E01.370.520.510', 'E04.510'], ['C23.550.767'], ['E04.100.700', 'E... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of sorghum particle size on digestibility of nutrients at the terminal ileum and over the total digestive tract of growing-finishing pigs. | The effect of sorghum particle size on nutrient digestibilities at the terminal ileum and over the total digestive tract of growing-finishing pigs were investigated in a replicated 3 X 3 Latin square trial. Sorghum-casein diets were used. Sorghum was dry rolled (C) or ground in a hammer mill through 6.4 mm (M) or 3.2 m... | ['Amino Acids', 'Animals', 'Caseins', 'Digestion', 'Digestive System', 'Ileum', 'Male', 'Particle Size', 'Poaceae', 'Swine'] | 7,263,529 | [['D12.125'], ['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['G07.203.650.250', 'G10.261.190'], ['A03'], ['A03.556.124.684.249', 'A03.556.249.124'], ['G02.712'], ['B01.650.940.800.575.912.250.822'], ['B01.050.150.900.649.313.500.880']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Global implications of regional grain production through virtual water trade. | Crop yields (Y) and virtual water content (VWC) of agricultural production are affected by climate variability and change, and are highly dependent on geographical location, crop type, specific planting and harvesting practice, soil property and moisture, hydro-geologic and climate conditions. This paper assesses and a... | ['Agriculture', 'Alberta', 'Brassica', 'Climate Change', 'Crops, Agricultural', 'Edible Grain', 'Hordeum', 'Models, Biological', 'Triticum', 'Water', 'Water Resources'] | 31,096,411 | [['J01.040'], ['Z01.107.567.176.064'], ['B01.650.940.800.575.912.250.157.200'], ['G16.500.175.374'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['B01.650.940.800.575... | ['Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Guided optimization of fluid status in haemodialysis patients. | BACKGROUND: Achieving normohydration remains a non-trivial issue in haemodialysis therapy. Guiding the haemodialysis patient on the path between fluid overload and dehydration should be the clinical target, although it can be difficult to achieve this target in practice. Objective and clinically applicable methods for ... | ['Body Composition', 'Body Fluids', 'Electric Impedance', 'Humans', 'Middle Aged', 'Monitoring, Physiologic', 'Prospective Studies', 'Renal Dialysis'] | 19,793,930 | [['G02.111.130', 'G03.180', 'G07.100.049'], ['A12.207'], ['G01.358.500.249.277.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E02.870.300', 'E02.912.800']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Antigenic analysis and immunological studies of the uterotropic bacterial strains SH6 and 01 isolated from aborted cows]. | The uterotropic strains SH6 and O1 were studied immunoelectrophoretically to establish their antigenic relationship. The more readily diffusing component of the O-antigenic fraction of the strains proved immunologically identical with LPA of the R Brucella organisms, while the slower component showed common determinan... | ['Abortion, Veterinary', 'Animals', 'Antigens, Bacterial', 'Bacterial Proteins', 'Brucella', 'Brucella abortus', 'Cattle', 'Cattle Diseases', 'Epitopes', 'Female', 'Immunodiffusion', 'Immunoelectrophoresis', 'Lipopolysaccharides', 'Pregnancy', 'Uterus', 'Yersinia'] | 60,821 | [['C13.703.039.422', 'C22.021'], ['B01.050'], ['D23.050.161'], ['D12.776.097'], ['B03.440.400.425.215.500', 'B03.660.050.070.100'], ['B03.440.400.425.215.500.100', 'B03.660.050.070.100.100'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['D23.050.550'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350'... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of feeding dry-rolled corn-based diets with and without wet distillers grains with solubles and zilpaterol hydrochloride on performance, carcass characteristics, and heat stress in finishing beef steers. | Zilpaterol hydrochloride (ZH) has been approved for use since 2006; however, there is no research on any interactions between ZH and coproducts. Additionally, there is no published information on the potential effects of ZH on heat stress in feedlot cattle. Therefore, an experiment was conducted to determine the effect... | ['Animal Feed', 'Animals', 'Body Composition', 'Cattle', 'Diet', 'Edible Grain', 'Heat-Shock Response', 'Meat', 'Respiratory Rate', 'Trimethylsilyl Compounds', 'Zea mays'] | 25,023,799 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['G07.775.... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Depressive symptoms in acute schizophrenic inpatients. | Prospective and longitudinal assessment of depressive, positive, and negative symptoms were performed on 86 newly admitted schizophrenic patients. The improvement of depressive symptoms was significantly correlated with the improvement in positive symptoms, but did not correlate with the improvement in negative symptom... | ['Adult', 'Antipsychotic Agents', 'Depressive Disorder', 'Female', 'Hospitalization', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Middle Aged', 'Schizophrenia', 'Schizophrenic Psychology'] | 9,187,012 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F03.600.300'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.700.750'], ['F04.824']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Further studies on bacteriophage T4 DNA synthesis in sucrose-plasmolyzed cells. | This paper describes several technical improvements in the sucrose-plasmolyzed cell system used in earlier experiments on DNA synthesis in situ with Escherichia coli infected by DNA-defective mutants of bacteriophage T4 (W. L. Collinsworth and C. K. Mathews, J. Virol. 13:908-915, 1974). Using this system, which is base... | ['Coliphages', 'Cytoplasm', 'DNA Replication', 'DNA, Viral', 'Deoxyribonucleotides', 'Escherichia coli', 'Genes', 'Mutation', 'Osmosis', 'Phenotype', 'Sucrose'] | 328,926 | [['B04.123.205'], ['A11.284.430.214'], ['G02.111.225', 'G05.226'], ['D13.444.308.568'], ['D13.695.201'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['G05.365.590'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['G05.695'], ['D09.698.629.305.770', 'D09.947.750.770']... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The noise sampling period: a new cause of apparent sensing malfunction of demand pacemakers. | Two patients with Omni-Stanicor pulse generators presented an apparent sensing problem characterized by intermittent reversion to fixed-rate pacing only during atrial fibrillation with a very rapid ventricular rate. Every fixed-rate cycle contained two unsensed beats. The first unsensed beat fell in the noise sampling ... | ['Aged', 'Atrial Fibrillation', 'Electric Power Supplies', 'Electrocardiography', 'Humans', 'Male', 'Middle Aged', 'Pacemaker, Artificial', 'Tachycardia'] | 83,638 | [['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['E07.305.124'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.305.250.750'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antigens associated with chemically induced intestinal carcinomas of rats. | Rabbits were immunized with extracts of primary or grafted intestinal adeno-carcinomas induced by carcinogenic drugs in inbred rats. After absorption with normal tissue extracts, the antisera were able to recognize three tumor-associated antigens. Two of them were glycoproteins, present in cancer cells but also, in tra... | ['Adenocarcinoma', 'Animals', 'Antigens, Neoplasm', 'Chemical Precipitation', 'Cross Reactions', 'Epitopes', 'Fluorescent Antibody Technique', 'Guanidines', 'Humans', 'Hydrazines', 'Immune Sera', 'Immunodiffusion', 'Immunoelectrophoresis', 'Intestinal Neoplasms', 'Neoplasm Transplantation', 'Neoplasms, Experimental', '... | 47,840 | [['C04.557.470.200.025'], ['B01.050'], ['D23.050.285'], ['E05.196.150', 'G02.159'], ['G12.122.281'], ['D23.050.550'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['D02.078.370'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin biosynthesis and secretion. | Studies are presented which support the concept that a cell membrane localized glucoreceptor system is involved in the insulin secretory response to glucose and that the specific stimulation of insulin synthesis by glucose reflects effects at both the transcriptional and posttranscriptional level. After 48 hours of fas... | ['Animals', 'Dactinomycin', 'Dietary Carbohydrates', 'Dose-Response Relationship, Drug', 'Fasting', 'Glucose', 'Glycopeptides', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Lectins', 'Polyribosomes', 'Precipitin Tests', 'Proinsulin', 'Protein Binding', 'RNA', 'Rats', 'Receptors, Drug', 'Transcription, Genet... | 1,093,883 | [['B01.050'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['G07.690.773.875', 'G07.690.936.500'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D09.947.875.359.448'], ['D09.400.420', 'D12.644.233'], ['D06.472.699.587.200.500.625', 'D12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Controlled fabrication of porous double-walled TiO2 nanotubes via ultraviolet-assisted anodization. | Double-walled TiO2 nanotubes with porous wall morphologies are fabricated by anodization under ultraviolet (UV) irradiation. TiO2 formed by anodization of Ti is activated to generate electrons and holes by UV and the anodization process is influenced by the photo-generated charges. As a consequence, morphologies of the... | ['Catalysis', 'Methylene Blue', 'Nanotubes', 'Photolysis', 'Porosity', 'Titanium', 'Ultraviolet Rays'] | 24,562,049 | [['G02.130'], ['D02.886.369.517', 'D03.633.300.783.517'], ['J01.637.512.850'], ['G02.740.685'], ['G01.374.710'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.578.891', 'G16.500.275.063.725.525.600', 'G16.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[COALL-80 therapy in the management of acute lymphoblastic leukemia in childhood--an interim report]. | In order to reduce the toxicity of the otherwise very effective childhood ALL treatment protocol BFM 76/79 asparaginase was omitted from the 4-drug induction regimen and placed as single drug before the intensification phase. In addition the effect of 3-monthly intermediate dose methotrexate (ID-MTX) pulses versus conv... | ['Adolescent', 'Asparaginase', 'Child', 'Child, Preschool', 'Daunorubicin', 'Drug Therapy, Combination', 'Female', 'Humans', 'Infant', 'Leukemia, Lymphoid', 'Male', 'Methotrexate', 'Prednisolone', 'Vincristine'] | 6,576,203 | [['M01.060.057'], ['D08.811.277.087.116'], ['M01.060.406'], ['M01.060.406.448'], ['D02.455.426.559.847.562.050.200', 'D04.615.562.050.200', 'D09.408.051.059.200'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.557.337.428', 'C15.604.515.560', 'C20.683.515.528'], ['D03.633.100.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multimodal Exercise Benefits Mobility in Older Adults With Visual Impairment: A Preliminary Study. | Evidence-based recommendations for interventions to reduce fall risk in older adults with visual impairment are lacking. Adapted tango dance (Tango) and a balance and mobility program (FallProof) have improved mobility, balance, and quality of life (QOL) in individuals with movement impairment. This study compared the ... | ['Accidental Falls', 'Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Dancing', 'Exercise Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Postural Balance', 'Quality of Life', 'Task Performance and Analysis', 'Treatment Outcome', 'Visually Impaired Persons'] | 25,562,206 | [['N06.850.135.122'], ['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['I03.450.642.287'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
BrainPrint: identifying subjects by their brain. | Introducing BrainPrint, a compact and discriminative representation of anatomical structures in the brain. BrainPrint captures shape information of an ensemble of cortical and subcortical structures by solving the 2D and 3D Laplace-Beltrami operator on triangular (boundary) and tetrahedral (volumetric) meshes. We deriv... | ['Algorithms', 'Alzheimer Disease', 'Biometric Identification', 'Brain', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Software', 'Subtraction Technique'] | 25,320,780 | [['G17.035', 'L01.224.050'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.740.225.500', 'N04.452.910.099'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Long-Term Outcome After Retro-Areolar Versus Peri-Tumoral Injection of Superparamagnetic Iron Oxide Nanoparticles (SPIO) for Sentinel Lymph Node Detection in Breast Cancer Surgery. | BACKGROUND/OBJECTIVE: SPIO is effective in sentinel node (SN) detection. No nuclear medicine department is needed, and no allergic reactions have occurred. This study aimed to compare retro-areolar and peri-tumoral SPIO injections regarding skin staining, detection rates and number of SNs.METHODS: Data on staining size... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Lobular', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetite Nanoparticles', 'Middle Aged', 'Neoplasm Invasiveness', 'Nipples', 'Prognosis', 'Sentinel Lymph Node', 'Sentinel Lymph Node Biopsy'] | 30,830,536 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.180.437', 'C17.800.090.500.437'], ['E05.318.372.500.750.24... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Expert opinion and controversies in musculoskeletal and sports medicine: core stabilization as a treatment for low back pain. | Although there are a wide variety of therapeutic exercises that have been proposed as treatments for low back pain (LBP), the last 20 years have seen the development of a substantial focus on the use of exercises that are intended to address intersegmental stability in the lumbar spine. These exercise programs are vary... | ['Exercise Therapy', 'Humans', 'Low Back Pain', 'Sports Medicine'] | 18,047,895 | [['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['H02.403.830']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The Global Burden of Cancer 2013. | IMPORTANCE: Cancer is among the leading causes of death worldwide. Current estimates of cancer burden in individual countries and regions are necessary to inform local cancer control strategies.OBJECTIVE: To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adj... | ['Adolescent', 'Adult', 'Age Distribution', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Disability Evaluation', 'Female', 'Global Health', 'Humans', 'Incidence', 'Life Expectancy', 'Male', 'Middle Aged', 'Neoplasms', 'Prevalence', 'Prognosis', 'Risk Factors', 'Sex Distribution', 'Sex Facto... | 26,181,261 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.400'], ['H02.403.371', 'N01.400.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.31... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Anteroventral third ventricular N-methyl-D-aspartate receptors, but not metabotropic glutamate receptors are involved in hemorrhagic AVP secretion. | This study aimed to investigate the roles of glutamate (Glu) receptors in the anteroventral third ventricular region (AV3V), a pivotal area for water, cardiovascular and neuroendocrine regulations, in causing vasopressin (AVP) secretion and other phenomena in response to bleeding. The effects of intracerebral infusions... | ['Analysis of Variance', 'Angiotensin II', 'Animals', 'Blood Glucose', 'Blood Pressure', 'Dizocilpine Maleate', 'Drug Interactions', 'Electrolytes', 'Excitatory Amino Acid Antagonists', 'Glycine', 'Heart Rate', 'Hemorrhage', 'Hypothalamus', 'Injections, Intraventricular', 'Male', 'N-Methylaspartate', 'Osmolar Concentra... | 15,925,145 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.455.426.559.847.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Leadership Transitions and the First 90 Days. | This department highlights change management strategies that may be successful in strategically planning and executing organizational change initiatives. In this article, the author discusses leadership role transitions and provides a framework for successfully navigating the crucial 1st 90 days in an executive leaders... | ['Humans', 'Leadership', 'Nurse Administrators', 'Organizational Innovation', 'Personnel Turnover', 'Professional Role'] | 27,011,151 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580'], ['N04.452.610'], ['N04.452.677.680'], ['F01.829.316.616.625']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Clinical efficacy of high-frequency oscillatory ventilation combined with pulmonary surfactant in treatment of neonatal pulmonary hemorrhage]. | OBJECTIVE: To explore the clinical efficacy of high-frequency oscillatory ventilation (HFOV) combined with pulmonary surfactant (PS) in the treatment of neonatal pulmonary hemorrhage (NPH).METHODS: A total of 122 neonates diagnosed with NPH between January 2010 and June 2014 were enrolled. After being stratified by ges... | ['Combined Modality Therapy', 'Female', 'Hemorrhage', 'High-Frequency Ventilation', 'Humans', 'Infant, Newborn', 'Lung Diseases', 'Male', 'Pulmonary Surfactants'] | 25,919,553 | [['E02.186'], ['C23.550.414'], ['E02.041.625.508', 'E02.880.820.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C08.381'], ['D27.505.954.796.600']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adverse events after surgery for nonmalignant colon polyps are common and associated with increased length of stay and costs. | BACKGROUND AND AIMS: Endoscopic resection (ER) is a safe and effective treatment for nonmalignant complex colorectal polyps (complex polyps). Surgical resection (SR) remains prevalent despite limited outcomes data. We aimed to evaluate SR outcomes for complex polyps and compare SR outcomes to those of ER.METHODS: We pe... | ['Adenoma', 'Aged', 'Colectomy', 'Colonic Polyps', 'Colonoscopy', 'Colorectal Neoplasms', 'Endoscopic Mucosal Resection', 'Female', 'Health Care Costs', 'Humans', 'Length of Stay', 'Logistic Models', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'United States'] | 26,828,760 | [['C04.557.470.035'], ['M01.060.116.100'], ['E04.210.219'], ['C23.300.825.411.235'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of genetic variants of ST8SIA2 and NCAM1 genes on seasonal mood changes and circadian preference in the general population. | ST8SIA2 and NCAM1 are functionally related genes forming polysialic acid (PSA) - neural cell adhesion molecule (NCAM) complex in suprachiasmatic nucleus (SCN), the regulating site of circadian biological rhythm. In this study, the relationship of ST8SIA2 and NCAM1 with circadian and seasonal rhythms of human behavior w... | ['Adult', 'Affect', 'CD56 Antigen', 'Circadian Rhythm', 'Female', 'Genetic Variation', 'Genotype', 'Healthy Volunteers', 'Humans', 'Male', 'Middle Aged', 'Phenotype', 'Polymorphism, Single Nucleotide', 'Seasons', 'Sialyltransferases', 'Young Adult'] | 29,215,920 | [['M01.060.116'], ['F01.470.047'], ['D12.776.395.550.200.250.520.156', 'D12.776.543.550.200.250.520.156', 'D23.050.301.264.894.156', 'D23.050.301.350.250.520.156', 'D23.101.100.894.156'], ['G07.180.562.190'], ['G05.365'], ['G05.380'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A simple method to determine leaf angles of grass species. | There are several very accurate methods to determine leaf angles in closed canopies. However, these are generally very time-consuming or require special equipment. Average canopy leaf angles were derived from simple height and blade length measurements. An exponential relationship between the height/length ratio and th... | ['Plant Leaves', 'Poaceae', 'Ultraviolet Rays'] | 10,944,161 | [['A18.024.812'], ['B01.650.940.800.575.912.250.822'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.578.891', 'G16.500.275.063.725.525.600', 'G16.500.750.775.525.600', 'N06.230.300.100.725.525.600']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quantitation of 25-OH-vitamin D (25OHD) using liquid tandem mass spectrometry (LC-MS-MS). | 25-OH-vitamin D (25OHD) is ordered and interpreted clinically in light of calcium balance and homeostasis. Various methodologies including immunoassay and chromatography are described for the measurement of 25OHD in biological fluids. It is well reported that all existing methods are challenging and require a high leve... | ['Chromatography, Liquid', 'Humans', 'Reference Standards', 'Reproducibility of Results', 'Tandem Mass Spectrometry', 'Vitamin D'] | 20,077,103 | [['E05.196.181.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.978.808'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.196.566.880'], ['D04.210.500.812.768']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Efficacy of â-lactam/â-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis | Mycobacterium tuberculosis (Mtb) expresses a broad-spectrum â-lactamase (BlaC) that mediates resistance to one of the highly effective antibacterials, â-lactams. Nonetheless, â-lactams showed mycobactericidal activity in combination with â-lactamase inhibitor, clavulanate (Clav). However, the mechanistic aspects of how... | ['Amoxicillin-Potassium Clavulanate Combination', 'Anti-Bacterial Agents', 'Bacterial Proteins', 'Cytoplasm', 'Mycobacterium tuberculosis', 'Oxidation-Reduction', 'beta-Lactam Resistance', 'beta-Lactamase Inhibitors'] | 28,548,640 | [['D02.065.589.099.374.160.060', 'D02.065.589.099.750.750.050.050.060', 'D02.886.108.750.750.050.050.060', 'D03.633.100.300.374.160.060', 'D03.633.100.300.750.750.050.050.500', 'D26.310.102'], ['D27.505.954.122.085'], ['D12.776.097'], ['A11.284.430.214'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of timing, sex, and age on site-specific gastrointestinal permeability testing in children and adults. | OBJECTIVES: Measurement of gastrointestinal (GI) permeability is commonly used in research and often used clinically. Despite its utility, little is known about sugar excretion timeframes or the potential effects of age and sex on GI permeability testing. We seek to determine the timeframes of sugar excretion and the p... | ['Adolescent', 'Adult', 'Age Factors', 'Biomedical Research', 'Cell Membrane Permeability', 'Child', 'Child, Preschool', 'Dietary Sucrose', 'Female', 'Humans', 'Intestinal Absorption', 'Intestinal Mucosa', 'Lactulose', 'Male', 'Middle Aged', 'Sex Factors', 'Sucrose', 'Time Factors', 'Young Adult'] | 20,081,547 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['H01.770.644.145'], ['G03.143.335', 'G04.175'], ['M01.060.406'], ['M01.060.406.448'], ['D09.301.831.250', 'D09.698.629.305.770.200', 'D09.947.500.250', 'D09.947.750.770.200', 'D27.720.372.300.353.609.750.250', 'G07.203.300.362.831.250', 'G07.20... | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
[Comparative analysis of the state of asthma prevalence in children from two nation-wide surveys in 1990 and 2000 year]. | OBJECTIVE: To find out the prevalence change of asthma in children aged 0 - 14 years during the ten years.METHODS: A nationwide randomized survey, covering 27 cities, 27 identical cities/municipalities were chosen for comparison which were divided into 6 sections: mid-south, southwest districts, east-China section, nor... | ['Adolescent', 'Age Factors', 'Asthma', 'Child', 'Child, Preschool', 'China', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Prevalence', 'Time Factors'] | 14,990,187 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.308.985.525.750', 'N01.224.935.5... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Defining and Measuring Sustainability in the Food & Fitness Initiative. | Several frameworks for defining and measuring sustainability in public health have been documented in the literature. For the Food & Fitness Initiative, sustainability was a central aim at the outset and was defined broadly throughout the project. Sustainability included not only funding and resources necessary to supp... | ['Adult', 'Community Participation', 'Community-Institutional Relations', 'Exercise', 'Female', 'Food', 'Health Promotion', 'Humans', 'Interviews as Topic', 'Leadership', 'Male', 'Middle Aged', 'Policy Making', 'Program Evaluation', 'Surveys and Questionnaires', 'United States'] | 30,176,770 | [['M01.060.116'], ['N02.421.143.212', 'N03.540.245.360'], ['N04.452.822.210'], ['G11.427.410.698.277', 'I03.350'], ['G07.203.300', 'J02.500'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420']... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psycholo... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Modulation of eosinophil chemotaxis and eosinophil chemotactic factor release by concanavalin A. | Concanavalin A (Con A) is not a chemotactic factor for guinea pig eosinophil leukocytes. It does, however, modulate the response of cells to neutrophil-derived eosinophil chemotactic factor (ECF) or to C5a. This effect occurs by a direct interaction of Con A with the target cell and is reversible by appropriate doses o... | ['Animals', 'Chemotaxis, Leukocyte', 'Concanavalin A', 'Dose-Response Relationship, Immunologic', 'Eosinophils', 'Guinea Pigs', 'Humans', 'Methylmannosides', 'Neutrophils'] | 631,923 | [['B01.050'], ['G04.198.424.233'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['G12.300'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.408.490.500', 'D09.408.514.700'], ['A1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The global biogeography of polyploid plants. | Deciphering the global distribution of polyploid plants is fundamental for understanding plant evolution and ecology. Many factors have been hypothesized to affect the uneven distribution of polyploid plants across the globe. Nevertheless, the lack of large comparative datasets has restricted such studies to local flor... | ['Biological Evolution', 'Forests', 'Phylogeography', 'Plants', 'Polyploidy'] | 30,697,006 | [['G05.045', 'G16.075'], ['G16.500.275.157.437', 'N06.230.124.343'], ['H01.158.273.343.335.500', 'H01.277.500.589'], ['B01.650'], ['C23.550.210.702', 'G05.365.590.175.677', 'G05.700.740']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Aortocoronary bypass for the threatened spread of acute myocardial infarction]. | 21 patients with unstable angina in the acute myocardial infarction period were treated by early surgery, on average on the 3th day after infarction. Resistance to medical therapy given in the coronary care unit, associating modern pharmacological agents and circulatory assistance, on the one hand, and the presence of ... | ['Acute Disease', 'Adult', 'Angina Pectoris', 'Coronary Artery Bypass', 'Female', 'Humans', 'Intra-Aortic Balloon Pumping', 'Male', 'Middle Aged', 'Mitral Valve Insufficiency', 'Myocardial Infarction', 'Postoperative Complications'] | 115,426 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Microbiological and chemical quality of water used in Colombian food industries]. | INTRODUCTION: Food safety is a public health concern that is recognized worldwide. Food-borne diseases affect millions of people throughout the world, although mainly in developing countries. The current study was performed within the framework of an inter-administrative agreement in Colombia that considers decisions f... | ['Colombia', 'Food Industry', 'Food Safety', 'Foodborne Diseases', 'Humans', 'Pilot Projects', 'Water Microbiology', 'Water Pollutants, Chemical', 'Water Supply'] | 21,713,344 | [['Z01.107.757.284'], ['J01.576.423'], ['J01.576.423.850.730.500', 'N06.850.601.500'], ['C25.723.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['D27.888.284.903.655'], ['J01.293.82... | ['Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Health economics and cost implications of anxiety and other mental disorders in the United States. | BACKGROUND: Mental disorders impose a multi-billion dollar burden on the economy each year; translating the burden into economic terms is important to facilitate formulating policies about the use of resources.METHODS: For direct costs, data were obtained from national household interview and provider surveys; for morb... | ['Anxiety Disorders', 'Cost of Illness', 'Direct Service Costs', 'Health Expenditures', 'Humans', 'Mental Disorders', 'United States'] | 9,829,010 | [['F03.080'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['N03.219.151.400.325', 'N05.300.375.250'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The role of oxidative stress in enantiomer-specific, bifenthrin-induced cytotoxicity in PC12 cells. | With the widespread use of synthetic pyrethroids (SPs), the various toxic effects of these compounds have attracted much interest with respect to the investigation of involved mechanisms. However, research on molecular mechanisms of enantioselective toxicity of SPs has been limited. Our previous investigations suggeste... | ['Animals', 'Cell Survival', 'Cytotoxins', 'Endocrine Disruptors', 'Insecticides', 'Oxidative Stress', 'PC12 Cells', 'Pyrethrins', 'Rats', 'Reactive Oxygen Species', 'Stereoisomerism', 'Structure-Activity Relationship'] | 19,950,221 | [['B01.050'], ['G04.346'], ['D27.888.569.213'], ['D27.505.696.353', 'D27.888.141'], ['D27.720.031.700.491', 'D27.888.723.491'], ['G03.673', 'G07.775.750'], ['A11.251.210.190.750', 'A11.251.860.180.750', 'A11.299.500'], ['D02.455.849.575.188.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.339.431', 'D01.650.77... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dry adsorbed emulsion: 2. Dissolution behaviour of an intricate formulation. | The behaviour of a pharmaceutical form, called dry adsorbed emulsion (DAE), containing a sparingly soluble drug (i.e. theophylline) was studied for dissolution drug release kinetic, in relation with DAE structure characterisation. In vitro dissolution testings were performed under different experimental conditions (med... | ['Adsorption', 'Bronchodilator Agents', 'Chemistry, Pharmaceutical', 'Delayed-Action Preparations', 'Emulsions', 'Microscopy, Electron, Scanning', 'Particle Size', 'Powders', 'Solubility', 'Theophylline'] | 11,879,752 | [['G01.030', 'G02.020'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['H01.158.703.007', 'H01.181.466'], ['D26.255.210', 'E02.319.300.253'], ['D20.280.260', 'D26.255.165.260'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G02.712'], ['D26.255.779'], ['G02.805'], ['D03.132.960.751', 'D03.633.100.759.758... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Peroxynitrite formation and apoptosis in transgenic sickle cell mouse kidneys. | BACKGROUND: In a previous study, nitric oxide synthases (NOS) were found to be strongly expressed in the tubular epithelium of kidneys of a transgenic mouse model of sickle cell disease (alphaHbetaS[betaMDD]). Because NOS activity is often associated with peroxynitrite formation when superoxide radical (.O-2) is presen... | ['Anemia, Sickle Cell', 'Animals', 'Apoptosis', 'Blotting, Western', 'Immunohistochemistry', 'Kidney', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Nitrates', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Tyrosine'] | 9,844,128 | [['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
N-terminal acetylation of melanophore-stimulating hormone in the pars intermedia of Xenopus laevis is a physiologically regulated process. | The N-terminal acetylation of melanophore-stimulating hormone (MSH) increases the melanotropic potency of the peptide. This modification may be important in amphibians, where MSH causes skin darkening during adaptation to black background. This study examines the acetylation status of the peptide in the toad Xenopus la... | ['Acetylation', 'Adaptation, Physiological', 'Animals', 'Chromatography, High Pressure Liquid', 'Dopamine', 'In Vitro Techniques', 'Melanocyte-Stimulating Hormones', 'Peptide Fragments', 'Pituitary Gland', 'Radioimmunoassay', 'Xenopus laevis', 'alpha-MSH'] | 2,823,159 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['G07.025', 'G16.012.500'], ['B01.050'], ['E05.196.181.400.300'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E05.481'], ['D06.472.699.327.935.531.750', 'D06.472.699.631.525.600.531.750', 'D12.644.400.400.935.531.750', 'D12... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictive power of sexual hormones and tumor markers in endometrial cancer. | OBJECTIVE: The purpose of the present study was to investigate the predictive power of sexual hormones and tumor markers in endometrial cancer.METHODS: A total of 135 healthy women were prospectively compared with 135 women who had histopathologically confirmed endometrial cancer. Both the groups of women were matched ... | ['Biomarkers, Tumor', 'Carcinoma, Endometrioid', 'Case-Control Studies', 'Endometrial Neoplasms', 'Female', 'Gonadal Steroid Hormones', 'Humans', 'Middle Aged', 'Pituitary Hormones', 'Predictive Value of Tests', 'Prospective Studies'] | 19,777,250 | [['D23.101.140'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.20... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effect of various factors during cryopreservation on the morphology and viability of several poikilothermic cell lines]. | This paper deals with the effect of several factors, during cryopreservation, on three poikilothermic cell lines using morphology and viability as indicators. It was proved that to avoid toxicity in the suspension medium is of vital importance for the outcome of freezing. In addition, one of the systems studied and of ... | ['Cell Line', 'Cell Survival', 'Cold Temperature', 'Cryopreservation', 'Time Factors'] | 2,089,503 | [['A11.251.210'], ['G04.346'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['G0... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A comparative genome analysis of gene expression reveals different regulatory mechanisms between mouse and human embryo pre-implantation development. | BACKGROUND: Pre-implantation development is a crucial step in successful implantation and pregnancy in mammals. It has been studied in depth, but mostly in laboratory animal models. Less is known about the regulatory mechanism involved in the pre-implantation development in humans and about the comparative aspects.METH... | ['Animals', 'Cleavage Stage, Ovum', 'Cluster Analysis', 'Embryo Implantation', 'Embryo, Mammalian', 'Embryonic Development', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Genome', 'Humans', 'Mice', 'Oligonucleotide Array Sequence Analysis', 'Pregnancy', 'Species Specificity'] | 20,459,759 | [['B01.050'], ['A16.166'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G08.686.784.170.104.500'], ['A16.254'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E05.393.332'], ['G05.308.310'], ['G05.360.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Evaluation of quality of life (QOL) and efficacy of drug therapy on nasal symptoms and QOL disturbances in the patients with Japanese Cedar Pollinosis during the season of 2003 in Kyushu and Okinawa districts]. | AIM: The aim of the study is to investigate nasal symptom severity (NSS) and disturbance of quality of life (QOLD) of patients with Japanese Cedar Pollinosis (JCP) during the JC season of 2003, and to evaluate the efficacy of drug treatment on the NSS/QOLD by the data based on disease specific Japan Rhino-conjunctiviti... | ['Adolescent', 'Adult', 'Aged', 'Anti-Allergic Agents', 'Child', 'Cryptomeria', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Nasal Mucosa', 'Pollen', 'Prevalence', 'Quality of Life', 'Rhinitis, Allergic, Seasonal', 'Seasons'] | 15,719,651 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.016'], ['M01.060.406'], ['B01.650.940.800.575.912.625.750.233'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Was the famous astronomer Copernicus also a nephrologist. | Nicolaus Copernicus (1473-1543), world-famous astronomer, born in Toru?, was also a Warmian canon (senior priest) and a physician to 4 consecutive prince-bishops of Warmia and of other Warmian canons. What medical conditions preoccupied Nicolaus Copernicus and whether they included kidney diseases can only be inferred ... | ['Astronomy', 'History, 16th Century', 'Nephrology', 'Poland'] | 21,614,777 | [['H01.671.065'], ['K01.400.475.750'], ['H02.403.429.580'], ['Z01.542.248.679']] | ['Disciplines and Occupations [H]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Observational cohort study of pediatric inpatients with central venous catheters at "intermediate risk" of thrombosis and eligible for anticoagulant prophylaxis. | The risk of deep vein thrombosis (DVT) among hospitalized children is rising.The optimal approach to DVT prophylaxis in children is unclear. This study set out to ascertain the prevalence of DVT among pediatric inpatients who neither have contraindications to nor absolute indications for prophylactic therapy. A prospec... | ['Anticoagulants', 'Catheterization, Central Venous', 'Child', 'Child Welfare', 'Confidence Intervals', 'Contraindications', 'Female', 'Hemorrhage', 'Humans', 'Inpatients', 'Intensive Care Units', 'Male', 'Pediatric Nursing', 'Population Surveillance', 'Prevalence', 'Prospective Studies', 'Quality Improvement', 'Qualit... | 20,657,002 | [['D27.505.954.502.119'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['M01.060.406'], ['I01.880.787.293'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E02.208'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['N02.278.388.493']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
Is there echinococcosis in West Africa? A refugee from Niger with a liver cyst. | BACKGROUND: Italy is presently facing an increase in immigration from sub-Saharan Africa through the Mediterranean Sea. Case reports of human cystic echinococcosis (CE) have been reported from most sub-Saharan countries. Therefore, an increase in the number of patients with CE coming from these areas in the Italian and... | ['Adult', 'Animals', 'Echinococcosis, Hepatic', 'Echinococcus granulosus', 'Humans', 'Italy', 'Libya', 'Liver', 'Male', 'Mediterranean Sea', 'Niger', 'Prevalence', 'Refugees', 'Zoonoses'] | 28,494,818 | [['M01.060.116'], ['B01.050'], ['C01.610.335.190.396.314', 'C01.610.518.314', 'C06.552.664.272'], ['B01.050.500.500.736.215.327.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['Z01.058.266.513'], ['A03.620'], ['Z01.756.592'], ['Z01.058.290.190.560'], ['E05.318.308.985.525.750', 'N01.224.935.59... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor. | In adult tissues and organs with high turnover rates, the generation of transit-amplifying cell (TAC) populations from self-renewing stem cells drives cell replacement. The role of stem cells is to provide a renewable source of cells that give rise to TACs to provide the cell numbers that are necessary for cell differe... | ['Animals', 'Cell Cycle', 'Gene Expression Regulation', 'Genome', 'Histone Code', 'Incisor', 'Mesenchymal Stem Cells', 'Mice', 'Polycomb Repressive Complex 1', 'Stem Cell Niche', 'Wnt Signaling Pathway'] | 29,874,594 | [['B01.050'], ['G04.144'], ['G05.308'], ['G05.360.340'], ['G02.111.570.060.360', 'G05.360.360'], ['A14.549.167.860.425'], ['A11.329.830.500', 'A11.872.590.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['D05.500.781.100', 'D08.811.464.938.750.280', 'D12.776.660.235.600.100', 'D12.776.664.235.800.100', 'D12.776.930... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental and Clinical Risk Factors for Delirium in a Neurosurgical Center: A Prospective Study. | BACKGROUND: Few reports of delirium-related risk factors have focused on environmental risk factors and clinical risk factors, such as white matter signal abnormalities on magnetic resonance imaging fluid attenuated inversion recovery images.METHODS: We prospectively enrolled 253 patients admitted to our neurosurgical ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cerebral Hemorrhage', 'Cerebral Infarction', 'Craniocerebral Trauma', 'Delirium', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Prospective Studies', 'Risk Factors', 'Subarachnoid Hemorrhage', 'Surgicenters', 'Young Adult'] | 28,412,481 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serum high-mobility group box 1 protein correlates with cognitive decline after gastrointestinal surgery. | BACKGROUND: Accumulating evidence has indicated that inflammation may act as a potential mechanism underlying post-operative cognitive dysfunction (POCD). High-mobility group box 1 (HMGB1), as a known late mediator of inflammation, is involved in the development of post-operative complications. Thus, we sought to deter... | ['Aged', 'Anesthesia, General', 'Biomarkers', 'Cognition Disorders', 'Cognitive Reserve', 'Digestive System Surgical Procedures', 'Educational Status', 'Elective Surgical Procedures', 'Female', 'Gastrointestinal Neoplasms', 'HMGB1 Protein', 'Humans', 'Inflammation', 'Interleukin-6', 'Liver Neoplasms', 'Male', 'Middle A... | 24,754,551 | [['M01.060.116.100'], ['E03.155.197'], ['D23.101'], ['F03.615.250'], ['F02.463.188.331'], ['E04.210'], ['N01.824.196'], ['E04.249'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['D12.776.260.356.300', 'D12.776.660.235.400.600.300', 'D12.776.664.235.400.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Anaphylactic reactions to chlorhexidine during urinary catheterisation]. | Three men of 65, 41 and 54 years old respectively, developed an anaphylactic reaction during a medical procedure. Two were under general anaesthesia and the third was undergoing urinary catheterisation. After allergy tests chlorhexidine, an ingredient in the gel which was used during the urinary catheterisation procedu... | ['Aged', 'Anaphylaxis', 'Anti-Infective Agents, Local', 'Chlorhexidine', 'Humans', 'Male', 'Middle Aged', 'Skin Tests', 'Urinary Catheterization'] | 18,062,599 | [['M01.060.116.100'], ['C20.543.480.099'], ['D27.505.954.122.187'], ['D02.078.370.141.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.225.812.871', 'E05.200.812.871', 'E05.478.594.890'], ['E01.370.390.820', 'E02.148.947', 'E05.157.500']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of cell surface receptors for the 86-kilodalton glycoprotein of human cytomegalovirus. | Cell surface receptors for the 86-kDa glycoprotein (gp86) of human cytomegalovirus (HCMV) were identified by using two monoclonal anti-idiotype antibodies that bear the internal image of gp86. These antibodies bound to cells permissive for HCMV infection by both ELISA and immunofluorescence assay and inhibited HCMV pla... | ['Antibodies, Monoclonal', 'Antigens, Viral', 'Cell Line', 'Cell Membrane', 'Cytomegalovirus', 'Enzyme-Linked Immunosorbent Assay', 'Fluorescent Antibody Technique', 'Glycoproteins', 'Humans', 'Immunoblotting', 'Immunoglobulin Idiotypes', 'Molecular Weight', 'Receptors, Virus', 'Viral Plaque Assay'] | 2,557,618 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.327'], ['A11.251.210'], ['A11.284.149'], ['B04.280.382.150.150'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.607.512.240',... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Randomised controlled clinical trial of standard versus echocardiographically guided ibuprofen treatment for patent ductus arteriosus in preterm infants: a pilot study. | OBJECTIVE: The aim of this study was to explore the efficacy of echocardiographically guided (EchoG) pharmacological closure of the ductus arteriosus in reducing the number of required ibuprofen doses without increasing the reopening rate.METHODS: We performed a randomised controlled trial that included 49 infants with... | ['Dose-Response Relationship, Drug', 'Ductus Arteriosus, Patent', 'Echocardiography', 'Female', 'Gestational Age', 'Humans', 'Ibuprofen', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases', 'Intention to Treat Analysis', 'Male', 'Pilot Projects', 'Standard of Care'] | 24,047,189 | [['G07.690.773.875', 'G07.690.936.500'], ['C14.240.400.340', 'C14.280.400.340', 'C16.131.240.400.340'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.701.430'], ['M01.060.703.520'], ['M01.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Connexin 32 and its derived homotypic gap junctional intercellular communication inhibit the migration and invasion of transfected HeLa cells via enhancement of intercellular adhesion. | The effects of connexin (Cx) and its derived homotypic gap junctional intercellular communication (GJIC) between tumor cells on the invasion of metastatic cancers and the underlying mechanisms remain unclear. In this study, we investigated the influence of Cx32 and the homotypic GJIC mediated by this Cx on the migratio... | ['Cell Adhesion', 'Cell Communication', 'Cell Movement', 'Connexins', 'Enzyme Activation', 'Extracellular Signal-Regulated MAP Kinases', 'Extracellular Space', 'Flow Cytometry', 'Gap Junctions', 'HeLa Cells', 'Humans', 'MAP Kinase Signaling System', 'Neoplasm Invasiveness', 'Oleic Acids', 'Transfection', 'p38 Mitogen-A... | 21,687,945 | [['G04.022'], ['G04.085'], ['G04.198', 'G07.568.500.180'], ['D12.776.543.585.250'], ['G02.111.263', 'G03.328'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['A10.082.500', 'A11.284.295'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluorescence digital image analysis of glucose-induced [Ca2+]i oscillations in mouse pancreatic islets of Langerhans. | At intermediate glucose concentrations, [Ca2+]i (intracellular calcium) measured in single islets of Langerhans undergo oscillations that are caused by glucose-induced bursting of electrical activity. Using digital video imaging of fura-2--loaded islets, we have analyzed the spatial distribution of [Ca2+]i in response ... | ['Animals', 'Calcium', 'Glucose', 'Image Processing, Computer-Assisted', 'In Vitro Techniques', 'Islets of Langerhans', 'Mice', 'Microscopy, Fluorescence', 'Tolbutamide'] | 8,325,454 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D09.947.875.359.448'], ['L01.224.308'], ['E05.481'], ['A03.734.414', 'A06.300.414'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.458', 'E05.595.458'], ['D02.065.950.828.896', 'D02.886.590.795.896']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Sudden sports deaths in the armed forces of Germany]. | All Soldiers are obliged to participate in sports educational programs of the services, with the exception of severe restrictions due to individual health problems. During sports activities from 1/1989 to 12/1995 7 soldiers died, 3 (i.e. 43%) during soccer games. Based on a troops strength of 370,000 men, we found a ye... | ['Athletic Injuries', 'Cause of Death', 'Death, Sudden', 'Germany', 'Humans', 'Male', 'Military Personnel', 'Soccer', 'Survival Rate'] | 9,592,920 | [['C26.115'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C23.550.260.322'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['I03.450.642.845.800'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The effect of gender and body composition method on the apparent decline in lean mass-adjusted resting metabolic rate with age. | BACKGROUND: Declining resting energy expenditure (REE) is a hallmark of normal aging, but the cause of this decline remains controversial. Some, but not all, studies have shown that the decline in REE with age is eliminated after adjustment for fat-free mass (FFM).METHODS: We examined the effect of four body compositio... | ['Adult', 'Aged', 'Aging', 'Body Composition', 'Electric Impedance', 'Energy Metabolism', 'Female', 'Humans', 'Male', 'Middle Aged', 'Rest', 'Sex Characteristics', 'Thinness'] | 11,129,399 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G01.358.500.249.277.350'], ['G03.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I03.450.769.647'], ['G08.686.815'], ['C23.888.144.828', 'E01.370.600.115.100.160.120.828', 'G07.100.100.160... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Are HIV positive patients resistant to statin therapy? | BACKGROUND: Patients with HIV are subject to development of HIV metabolic syndrome characterized by dyslipidemia, lipodystrophy and insulin resistance secondary to highly active antiretroviral therapy (HAART). Rosuvastatin is a highly potent HMG-CoA reductase inhibitor. Rosuvastatin is effective at lowering LDL and pos... | ['Cholesterol', 'Drug Resistance, Multiple, Viral', 'Dyslipidemias', 'Female', 'Fluorobenzenes', 'HIV Infections', 'HIV Seropositivity', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Male', 'Middle Aged', 'Pyrimidines', 'Retrospective Studies', 'Rosuvastatin Calcium', 'Sulfonamides'] | 17,958,912 | [['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['G06.225.420.500', 'G06.920.225.500', 'G07.690.773.984.269.420.500', 'G07.690.773.984.300.750'], ['C18.452.584.500'], ['D02.455.426.559.389.358', 'D02.455.526.510.432'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.78... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Poor continuity of care for TB diagnosis and treatment in Zambian Prisons: a situation analysis. | OBJECTIVES: Prisons act as infectious disease reservoirs. We aimed to explore the challenges of TB control and continuity of care in prisons in Zambia.METHODS: We evaluated treatment outcomes for a cohort of inmates diagnosed with TB during a TB REACH funded screening programme initiated by the Zambia Prisons Service a... | ['Adult', 'Antitubercular Agents', 'Continuity of Patient Care', 'Humans', 'Male', 'Medication Adherence', 'Middle Aged', 'Prisons', 'Public Health', 'Time Factors', 'Tuberculosis', 'Young Adult', 'Zambia'] | 29,230,918 | [['M01.060.116'], ['D27.505.954.122.085.255'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.600.500', 'F01.145.488.887.500.600.500', 'N05.300.150.800.500.600.500'], ['M01.060.116.630'], ['I01.880.604.787', 'J03.220.500'], ['H02.403.720... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occup... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Mammary analogue secretory carcinoma of parotid: Is preoperative cytological diagnosis possible? | Mammary analogue secretory carcinoma is a recently recognized tumor of salivary gland with characteristic t(12;15)(q13;q25) that results in ETV6-NTRK3 fusion product. Distinguishing mammary analogue secretory carcinoma from other salivary gland tumors is important. Present study highlights cytologic findings in three c... | ['Adolescent', 'Biomarkers, Tumor', 'Biopsy, Fine-Needle', 'Child', 'Female', 'Humans', 'Male', 'Mammary Analogue Secretory Carcinoma', 'Middle Aged', 'Oncogene Proteins, Fusion', 'Parotid Neoplasms', 'S100 Proteins'] | 26,945,684 | [['M01.060.057'], ['D23.101.140'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Improved leishmanicidal effect of phosphorotioate antisense oligonucleotides by LDL-mediated delivery. | We have designed antisense oligonucleotides that can interact with lipoproteins in order to use them as vectors to facilitate the uptake by those cells expressing the corresponding receptor. Phosphorothioate (PS) oligonucleotides were linked at the 5' end to a palmityl group giving rise to PSPal conjugates. Such a modi... | ['Animals', 'Antiprotozoal Agents', 'Base Sequence', 'Cells, Cultured', 'Drug Carriers', 'Exons', 'Humans', 'Kinetics', 'Leishmania', 'Lipoproteins, LDL', 'Macrophages, Peritoneal', 'Male', 'Mice', 'Molecular Sequence Data', 'Oligonucleotides, Antisense', 'Palmitic Acids', 'Thionucleotides'] | 7,495,868 | [['B01.050'], ['D27.505.954.122.250.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['D26.255.260', 'E02.319.300.380'], ['G05.360.340.024.340.137.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['B01.268.475.868.488'], ['D10.532.515', 'D12.776.521.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Large scale in silico characterization of repeat expansion variation in human genomes. | Significant progress has been made in elucidating single nucleotide polymorphism diversity in the human population. However, the majority of the variation space in the genome is structural and remains partially elusive. One form of structural variation is tandem repeats (TRs). Expansion of TRs are responsible for over ... | ['Alu Elements', 'Datasets as Topic', 'Genome, Human', 'Humans', 'Polymorphism, Single Nucleotide', 'Tandem Repeat Sequences'] | 32,901,039 | [['G02.111.570.080.708.330.800.800.050', 'G05.360.080.708.330.800.800.050', 'G05.360.340.024.425.800.800.050'], ['E05.318.308.056', 'L01.313.500.750.300.188.400.500', 'L01.399.250.224', 'L01.470.750.750.431', 'N05.715.360.300.224', 'N06.850.520.308.056'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Challenges in the Operationalization of Mental Health Quality Measures: An Assessment of Alternatives. | Interest in measuring the quality of mental health services has increased, but challenges remain in moving from general standards of quality and best practices to specific, implementable quality measures. The International Initiative for Mental Health Leadership identified 656 mental health quality measures and then ap... | ['Delphi Technique', 'Humans', 'Mental Health Services', 'Quality Indicators, Health Care'] | 27,301,768 | [['L01.906.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.408', 'N02.421.461'], ['N04.761.789', 'N05.715.760']] | ['Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Development of an inducible system to control and easily monitor gene expression in Lactococcus lactis. | This report describes the implementation and use of a maltose-inducible system for regulated gene expression in Lactococcus lactis. The system was established using Green Fluorescent Protein as reporter. The transcription of a gene of interest from the inducible promoter of pLS1RGFP plasmid vector can be easily monitor... | ['Blotting, Western', 'DNA Primers', 'Gene Expression Regulation, Bacterial', 'Genes, Reporter', 'Genetic Vectors', 'Green Fluorescent Proteins', 'Lactococcus lactis', 'Luminescent Proteins', 'Maltose', 'Microscopy, Fluorescence', 'Plasmids', 'Ribonuclease III'] | 15,109,832 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.300'], ['G05.360.340.024.340.435'], ['G05.360.337'], ['D12.776.532.265'], ['B03.353.750.737.500.400', 'B03.510.400.800.500.400', 'B03.510.550.737.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.