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Predicting medical and surgical complications of carotid endarterectomy: comparing the risk indexes. | BACKGROUND: Several generic cardiac risk assessment tools predict perioperative cardiac complications, but their ability to predict a broader range of medical, neurologic, and surgical complications is unknown.METHODS: A multicenter retrospective observational cohort study of 1998 patients undergoing carotid endarterec... | ['Aged', 'Carotid Artery Diseases', 'Endarterectomy, Carotid', 'Female', 'Follow-Up Studies', 'Heart Diseases', 'Humans', 'Incidence', 'Male', 'New York', 'Postoperative Complications', 'Prognosis', 'Retrospective Studies', 'Risk Assessment', 'Stroke', 'Survival Rate'] | 16,636,219 | [['M01.060.116.100'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E04.100.814.456.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A CAD-CAM-prototyped temporomandibular condyle connected to a bony plate to support a free fibula flap in patients undergoing mandiblectomy: A pilot study with 5 years of follow up. | Reconstruction of the condyle after an ablative procedure with the aim of cancer elimination remains surgically challenging. This pilot study focused on mandibular condylar replacement using CAD-CAM temporomandibular prostheses connected to customized reconstructive plates to support free fibula flaps in oncological pa... | ['Bone Plates', 'Computer-Aided Design', 'Fibula', 'Follow-Up Studies', 'Free Tissue Flaps', 'Humans', 'Mandibular Condyle', 'Mandibular Neoplasms', 'Mandibular Prosthesis', 'Mandibular Reconstruction', 'Pilot Projects'] | 27,235,153 | [['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['L01.224.108.150', 'L01.296.110.150'], ['A02.835.232.043.650.321'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A10.850.710.500', 'E07.862.710.500'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of different doses in continuous veno-venous hemofiltration on plasma lactate in critically ill patients. | BACKGROUND: Many studies have shown that continuous renal replacement therapy (CRRT) could clean lactate and treat the hyper-lactatemia. On the contrary, some other studies found that filter lactate clearance only accounted for a very small part of total lactate clearance and the hemofilter's contribution to the overal... | ['Adult', 'Aged', 'Aged, 80 and over', 'Critical Illness', 'Female', 'Hemofiltration', 'Humans', 'Lactic Acid', 'Male', 'Middle Aged'] | 24,824,239 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.291.625'], ['E02.870.225', 'E04.292.471'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Splenic outer periarterial lymphoid sheath (PALS): an immunoproliferative microenvironment constituted by antigen-laden marginal metallophils and ED2-positive macrophages in the rat. | In an attempt to reveal the role of antigen-laden marginal metallophil (MM) and other macrophages in the intrasplenic immune response of a specific B-cell lineage to a thymus-independent type-2 antigen (Ficoll conjugated with fluorescein isothiocyanate), simultaneous immunohistological observations of the involved cell... | ['Animals', 'Antibodies, Monoclonal', 'Arteries', 'B-Lymphocytes', 'Bromodeoxyuridine', 'Lymphocyte Activation', 'Macrophages', 'Male', 'Rats', 'Rats, Inbred Strains', 'Spleen'] | 2,790,931 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A07.015.114'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Salivary gland tumours: 25 years of experience from a single institution in Croatia. | INTRODUCTION: The aim of this study was to determine the types, frequency, distribution, and demographic characteristics of salivary gland tumours in a large representative sample.PATIENTS AND METHODS: We retrospectively analysed the medical records of 779 patients with tumours of the salivary glands surgically treated... | ['Adenolymphoma', 'Adenoma, Pleomorphic', 'Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Carcinoma', 'Carcinoma, Adenoid Cystic', 'Carcinoma, Mucoepidermoid', 'Child', 'Child, Preschool', 'Croatia', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Palatal Neoplasms', 'Parotid Neoplasms', 'Retr... | 21,641,811 | [['C04.557.435.075'], ['C04.557.435.090', 'C04.557.470.035.155'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200'], ['C04.557.470.200.025.220'], ['C04.557.470.200.025.340', 'C04.557.470.590.340'], ['M01.060.406'], ['M01.060.406.4... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Acute coronary artery dissection after aortic valve replacement]. | Late aortic dissection can occur after aortic valve replacement surgery, but rarely in the first postoperative month. Coronary artery dissection is rare and usually occurs after coronary angiography. We report a rare case of coronary artery dissection followed by myocardial infarction in the immediate postoperative per... | ['Aged', 'Aneurysm, Dissecting', 'Aortic Valve', 'Coronary Aneurysm', 'Female', 'Heart Valve Prosthesis Implantation', 'Humans', 'Hypertension', 'Myocardial Infarction', 'Postoperative Complications', 'Postoperative Period', 'Radiography'] | 20,428,604 | [['M01.060.116.100'], ['C14.907.055.050'], ['A07.541.510.110'], ['C14.280.647.250.250', 'C14.907.055.395', 'C14.907.585.250.250'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.5... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
East African megadroughts between 135 and 75 thousand years ago and bearing on early-modern human origins. | The environmental backdrop to the evolution and spread of early Homo sapiens in East Africa is known mainly from isolated outcrops and distant marine sediment cores. Here we present results from new scientific drill cores from Lake Malawi, the first long and continuous, high-fidelity records of tropical climate change ... | ['Africa, Eastern', 'Animals', 'Biological Evolution', 'Disasters', 'Hominidae', 'Humans', 'Paleontology', 'Population', 'Tropical Climate'] | 17,785,420 | [['Z01.058.290.120'], ['B01.050'], ['G05.045', 'G16.075'], ['N06.230.100'], ['B01.050.150.900.649.313.988.400.112.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.277.875', 'I01.076.368.584'], ['N01.600'], ['G16.500.275.071.600', 'N06.230.300.100.250.600']] | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Occurrence and relative abundance of mosquitoes in stormwater retention facilities in North Carolina, U.S.A. | Throughout the 2004 mosquito season, 52 stormwater retention facilities were sampled to characterize the seasonal occurrence and relative abundance of mosquito species in relation to the structural complexity and biological diversity of the facilities. The three different types of facilities included standard wet ponds... | ['Animals', 'Culicidae', 'North Carolina', 'Rain', 'Species Specificity', 'United States', 'Wetlands'] | 17,120,664 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['G16.824'], ['Z01.107.567.875'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effect of risk-based payment model on caries inequalities in preschool children assessed by geo-mapping. | BACKGROUND: To describe, with aid of geo-mapping, the effects of a risk-based capitation model linked to caries-preventive guidelines on the polarization of caries in preschool children living in the Halland region of Sweden.METHODS: The new capitation model was implemented in 2013 in which more money was allocated to ... | ['Capitation Fee', 'Child', 'Child, Preschool', 'Dental Caries', 'Female', 'Geography, Medical', 'Health Status Disparities', 'Humans', 'Male', 'Models, Economic', 'Risk Factors', 'Sweden'] | 29,304,785 | [['N03.219.442.090'], ['M01.060.406'], ['M01.060.406.448'], ['C07.793.720.210'], ['H01.277.500.097', 'H02.403.352'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.600', 'E05.599.835.890', 'N05.715.360.750.530.500', 'N06.850.520.830.... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Neurohypophyseal hormone-sensitive adenyl cyclase of toad urinary bladder. | An adenyl cyclase preparation derived from epithelial cells of the urinary bladder of the toad, Bufo marinus, is described. This cyclase preparation is specifically stimulated by neurohypophyseal hormones and various synthetic analogs which evoke a hydroosmotic response in the intact bladder. The relative stimulatory e... | ['Adenylyl Cyclases', 'Animals', 'Anura', 'Enzymes', 'Epithelium', 'Oxytocin', 'Prostaglandins', 'Stimulation, Chemical', 'Urinary Bladder', 'Vasopressins'] | 5,272,332 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['B01.050.150.900.090.180'], ['D08.811'], ['A10.272'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['G07.690.773.996'], ['A05.810.890'], ['D06.472.699.631.692.781', 'D12.644.400.900',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The histopathology of uterine leiomyomas following treatment with gonadotropin-releasing hormone analogues. | Gonadotropin-releasing hormone analogues (GnRH agonists) cause pituitary desensitization by downregulation of GnRH receptors, decrease gonadal steroid production, and reduce uterine volume in women with leiomyomas. The purpose of this study was to examine the morphologic changes in uterine leiomyomas associated with Gn... | ['Adult', 'Combined Modality Therapy', 'Female', 'Gonadotropin-Releasing Hormone', 'Humans', 'Hysterectomy', 'Leiomyoma', 'Middle Aged', 'Necrosis', 'Retrospective Studies', 'Uterine Neoplasms'] | 8,406,417 | [['M01.060.116'], ['E02.186'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['C04.557.450.590.450'], ['M01.060.116.630'], ['C23.550.717'], ['E05.318.372.500.500.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of enhanced recovery after surgery program on patient-reported outcomes and function recovery in patients undergoing liver resection for hepatocellular carcinoma. | The aim of this study was to investigate the effect of enhanced recovery after surgery (ERAS) on perioperative outcomes, with an emphasis on patient-reported outcomes (PROs) and functional recovery.We compared the clinical outcomes in a cohort of 275 patients undergoing liver resection before and after the implementati... | ['Adult', 'Aged', 'Carcinoma, Hepatocellular', 'Cohort Studies', 'Enhanced Recovery After Surgery', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Patient Reported Outcome Measures', 'Recovery of Function', 'Treatment Outcome', 'Young Adult'] | 32,443,312 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.604.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.69... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
One Special Glomerulus in the Olfactory Bulb of Xenopus laevis Tadpoles Integrates a Broad Range of Amino Acids and Mechanical Stimuli. | The olfactory system senses odors, but not exclusively, as shown over the past years. It also registers other modalities such as temperature and pressure. However, it remains unknown how widespread these sensitivities are across species and how strongly their processing is interconnected with the processing of odors. H... | ['Amino Acids', 'Animals', 'Female', 'Larva', 'Male', 'Mechanotransduction, Cellular', 'Odorants', 'Olfactory Bulb', 'Olfactory Perception', 'Physical Stimulation', 'Pressure', 'Xenopus laevis'] | 27,798,179 | [['D12.125'], ['B01.050'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G01.154.090.500', 'G02.111.820.580', 'G04.835.580'], ['G16.500.275.640', 'N06.230.480'], ['A08.186.211.200.885.388'], ['F02.463.593.485'], ['E05.723'], ['G01.374.715'], ['B01.050.150.900.090.180.610.500.562']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Plasma, serum and whole-blood viscosity variations with age, sex, and smoking habits. | To study the influence of age, sex, and smoking habits on rheology, the authors measured plasma (PV), serum (SV), native (NBV), and corrected (CBV) blood viscosity with a computerized rotational viscometer in 152 blood donors (86 men and 66 women) and in 20 healthy persons (4 men and 16 women) attending smoke aversion ... | ['Adult', 'Age Factors', 'Aged', 'Blood Sedimentation', 'Blood Viscosity', 'Female', 'Fibrinogen', 'Hematocrit', 'Humans', 'Male', 'Middle Aged', 'Sex Factors', 'Smoking'] | 8,480,916 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.225.625.125', 'E05.200.625.125'], ['G09.188.370.124', 'G09.330.380.630.110'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['B01.05... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prenatal and early childhood bisphenol A concentrations and behavior in school-aged children. | INTRODUCTION: Early life exposure to bisphenol A (BPA), an endocrine disrupting chemical used in some food and beverage containers, receipts, and dental sealants, has been associated with anxiety and hyperactivity in animal studies. A few human studies also show prenatal and childhood BPA exposure to be associated with... | ['Aggression', 'Anxiety', 'Attention', 'Benzhydryl Compounds', 'Child', 'Child Behavior', 'Child, Preschool', 'Depression', 'Dyskinesia, Drug-Induced', 'Endocrine Disruptors', 'Environmental Exposure', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Phenols', 'Pregnancy', 'Prenatal Exposure Delayed Effects'] | 23,870,093 | [['F01.145.126.125', 'F01.145.813.045'], ['F01.470.132'], ['F02.830.104.214'], ['D02.455.426.559.389.115'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['F01.145.126.350'], ['C10.228.662.262.500', 'C10.597.350.275', 'C10.720.312', 'C23.888.592.350.275', 'C25.100.750', 'C25.723.705.200'], ['D27.505.696.353', ... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of Specific Core Re-Warm-Ups on Core Function, Leg Perfusion and Second-Half Team Sport-Specific Sprint Performance: A Randomized Crossover Study. | This study examined the effects of a specific core exercise program, as a re-warm-up regime during the half-time period, on inspiratory (IM) and core (CM) muscle functions, leg perfusion and the team sport-specific sprint performance in the initial stage of the second half of a simulated exercise task. Nine team-sports... | ['Athletic Performance', 'Cross-Over Studies', 'Exercise Test', 'Humans', 'Inhalation', 'Leg', 'Male', 'Muscle, Skeletal', 'Respiratory Muscles', 'Running', 'Warm-Up Exercise', 'Young Adult'] | 31,427,870 | [['I03.450.642.845.054'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.772.705.700.390'], ['A01.378.610.500'], ['A02.633.567', 'A10.690.552.500'], ['A02.633.567.900'], ['G11.427.41... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Basilar artery occlusion therapy for giant aneurysm: hemodynamic analysis by hydraulic vascular model]. | Therapeutic occlusion of the basilar artery has been one of the alternative treatments for surgically or intravascularly inaccessible basilar bifurcation giant aneurysms. However, several problems have been reported, such as incomplete thrombosis of the aneurysms, their growth or rupture, and cerebral embolism originat... | ['Basilar Artery', 'Cerebrovascular Circulation', 'Embolization, Therapeutic', 'Hemodynamics', 'Humans', 'Intracranial Aneurysm', 'Models, Biological', 'Models, Cardiovascular', 'Pulsatile Flow', 'Vascular Resistance'] | 1,448,190 | [['A07.015.114.106'], ['G09.330.100.159'], ['E02.520.360', 'E02.926.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['E05.599.395'], ['E05.599.395.161'], ['G01.482.620', 'G09.330.380.630.555'], ['G09.330.380.921']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative efficacy of fluoroquinolones, aminoglycosides, ureidopenicillins & newer cephalosporins against Pseudomonas species. | A total of 74 strains of Pseudomonas aeruginosa and 18 strains of Ps. putrefaciens were tested for sensitivity to 14 different antimicrobial agents. Ps. aeruginosa were mostly sensitive to netilmicin (81%), piperacillin (78%), amikacin (73%), azlocillin (70%), ceftazidime (69%) and pefloxacin (65%). Only 66 per cent st... | ['4-Quinolones', 'Aminoglycosides', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Cephalosporins', 'Microbial Sensitivity Tests', 'Penicillins', 'Pseudomonas'] | 1,506,063 | [['D03.633.100.810.835.830'], ['D09.408.051'], ['D27.505.954.122.085'], ['D27.505.954.122'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D02.065.589.099.750', 'D02.886.108.750', 'D03.633.100.300.750'], ['B03.440.400.425.625.625', 'B... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predicting communicative competence at 2 and 3 years from pragmatic skills at 10 months. | It is proposed that children play an important part in determining the kinds of linguistic experience they receive, influencing their language environment by means of early pragmatic communication. These early behaviours may also be predictive of later communicative competence. As a preliminary investigation into the w... | ['Child Behavior', 'Child Language', 'Child, Preschool', 'Communication', 'Female', 'Humans', 'Infant', 'Language Development', 'Language Development Disorders', 'Language Tests', 'Longitudinal Studies', 'Male', 'Predictive Value of Tests'] | 9,709,433 | [['F01.145.179'], ['F01.525.200.310.250'], ['M01.060.406.448'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.525.200.310'], ['C10.597.606.150.500.550', 'C23.888.592.604.150.500.550'], ['F04.711.513.240'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', '... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Studies on drug metabolism in obese men and mice (author's transl)]. | In 7 obese patients with an overweight of 53 +/- 19% of Broca we found a 2-fold enlarged apparent volume of distribution and a nearly 2-fold prolonged elimination halflife of hexobarbital; the hexobarbital plasma clearance however, which is nearly identical with the metabolizing capacity of the liver for hexobarbital, ... | ['Adolescent', 'Adult', 'Animals', 'Enzyme Induction', 'Fatty Liver', 'Female', 'Hexobarbital', 'Humans', 'Male', 'Mice', 'Mice, Obese', 'Microsomes, Liver', 'Middle Aged', 'Obesity', 'Phenobarbital'] | 433,368 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of celiac ganglionectomy on tachykinin innervation, receptor distribution and intestinal responses in the rat. | Substance P (SP) is an important neurotransmitter in the control of intestinal motility and is found in both the enteric and sympathetic nervous systems. This study examined the effect of celiac ganglionectomy on (1) mechanical properties of the circular muscles of the duodenum, ileum and proximal colon, (2) circular m... | ['Animals', 'Ganglia, Sympathetic', 'Ganglionectomy', 'Immunohistochemistry', 'In Vitro Techniques', 'Intestinal Mucosa', 'Intestines', 'Male', 'Muscle Contraction', 'Muscle, Smooth', 'Neurokinin A', 'Norepinephrine', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Tachykinin', 'Substance P', 'Tachykinins'] | 8,988,488 | [['B01.050'], ['A08.340.315.350', 'A08.800.050.300.300', 'A08.800.050.800.300'], ['E04.525.210.105.800.380'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512'... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
How Food Rules at Home Influence Independent Adolescent Food Choices. | PURPOSE: The prevalence of unhealthy dietary behaviors among adolescents is high. We examined the effect of having health-oriented food rules at home on the healthiness of adolescents' independent food choices, and the necessity of parental oversight for such rules to be effective.METHODS: We surveyed a socioeconomical... | ['Adolescent', 'Cross-Sectional Studies', 'Diet, Healthy', 'Feeding Behavior', 'Female', 'Food Preferences', 'Health Behavior', 'Humans', 'Male', 'Parents', 'San Francisco', 'Students', 'Surveys and Questionnaires'] | 29,779,673 | [['M01.060.057'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.829.458.205.500', 'G07.203.650.240.629'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.145.407.516', 'G07.203.650.353.516'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Different influences of DNA purity indices and quantity on PCR-based DGGE and functional gene microarray in soil microbial community study. | Based on the comparative study of the DNA extracts from two soil samples obtained by three commercial DNA extraction kits, we evaluated the influence of the DNA quantity and purity indices (the absorbance ratios A260/280 and A260/230, as well as the absorbance value A320 indicating the amount of humic substances) on po... | ['Bacteriological Techniques', 'Biodiversity', 'DNA, Bacterial', 'Electrophoresis, Gel, Two-Dimensional', 'Humic Substances', 'Oligonucleotide Array Sequence Analysis', 'Polymerase Chain Reaction', 'Reagent Kits, Diagnostic', 'Reproducibility of Results', 'Soil Microbiology'] | 19,247,649 | [['E01.370.225.875.150', 'E05.200.875.150'], ['G16.500.275.157.049', 'N06.230.124.049'], ['D13.444.308.212'], ['E05.196.401.250', 'E05.301.300.230'], ['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['E05.393.620.500'], ['D27.505.25... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Quantitative analysis of somatostatin receptor subtype (SSTR1-5) gene expression levels in somatotropinomas and non-functioning pituitary adenomas. | OBJECTIVE: It is believed that the variable effectiveness of somatostatin analogs in post-surgical management of somatotropinomas and non-functioning pituitary adenomas (NFPA) may be due in part to variable expression of somatostatin receptor isoforms (SSTR1-5), within and between pituitary tumor types.DESIGN AND METHO... | ['Acromegaly', 'Adenoma', 'Adult', 'Antisense Elements (Genetics)', 'DNA Primers', 'Female', 'Follow-Up Studies', 'Gene Dosage', 'Gene Expression', 'Gene Expression Regulation, Neoplastic', 'Human Growth Hormone', 'Humans', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Octreotide', 'Pituitary Neoplasms', 'RNA, Mes... | 17,218,727 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['C04.557.470.035'], ['M01.060.116'], ['D13.150', 'D13.444.600.150', 'D27.720.470.530.600.150'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell surface markers. | The ability to purify to homogeneity a population of hepatic progenitor cells from adult liver is critical for their characterization prior to any therapeutic application. As a step in this direction, we have used a bipotential liver cell line from 14 days postcoitum mouse embryonic liver to compile a list of cell surf... | ['Animals', 'Antigens, Differentiation', 'Antigens, Surface', 'Bile Ducts', 'Biomarkers', 'Cell Differentiation', 'Cells, Cultured', 'Dihydropyridines', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Hepatocytes', 'Lipopolysaccharides', 'Liver', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CB... | 17,641,245 | [['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['D23.050.301'], ['A03.159.183'], ['D23.101'], ['G04.152'], ['A11.251'], ['D03.383.725.203'], ['E05.393.332'], ['G05.308.310'], ['A11.436.348'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A03.620'], ['B01.050.150.900.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Double-antigen sandwich ELISA for detection of antibodies to SARS-associated coronavirus in human serum. | The study presented here was conducted to evaluate the performance of a double-antigen sandwich ELISA to detect antibodies in human serum against the coronavirus associated with severe acute respiratory syndrome (SARS). A recombinant partial nucleocapsid protein of SARS-associated coronavirus was used as a serodiagnost... | ['Antibodies, Viral', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Nucleocapsid Proteins', 'Recombinant Proteins', 'SARS Virus', 'Severe Acute Respiratory Syndrome'] | 16,133,409 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.964.970.600'], ['D12.776.828'], ['B04.820.578.50... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Threonine 576 residue of amyloid-â precursor protein regulates its trafficking and processing. | Deposition of amyloid-â (Aâ) in the brain is the main culprit of Alzheimer's disease (AD). Aâ is derived from sequential proteolytic cleavage of amyloid-â precursor protein (APP). Newly synthesized APP is transported from endoplasmic reticulum to the plasma membrane via trans-Golgi network (TGN) after post-translationa... | ['Amyloid beta-Protein Precursor', 'Glycosylation', 'HeLa Cells', 'Humans', 'Mutation', 'Organelles', 'Protein Processing, Post-Translational', 'Protein Transport', 'Threonine'] | 26,471,307 | [['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['A11.284.430.214.190.875'], ['G02.111.660.871.790.60... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of DVT diseases using numerical simulations. | This research provides useful insights for better diagnosis and understanding the vein blockage induced by a deep venous thrombosis and the occurrence of reverse flow in human veins, allowing a proper detection of serious diseases related to deep venous insufficiency. An arbitrary Lagrangian-Eulerian formulation is use... | ['Humans', 'Models, Biological', 'Venous Thrombosis'] | 26,780,462 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['C14.907.355.830.925']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation Between Standardized Uptake Value in Preneoadjuvant and Postneoadjuvant Chemoradiotherapy and Tumor Regression Grade in Patients With Locally Advanced Esophageal Cancer. | PURPOSE: To investigate whether positron emission tomography/computed tomography (PET/CT) initial and restaging imaging predicts for pathologic response measured by tumor regression grade (TRG) after preoperative chemoradiotherapy (CRT) in patients with locally advanced esophageal cancer.METHODS: A retrospective review... | ['Adult', 'Aged', 'Chemoradiotherapy, Adjuvant', 'Esophageal Neoplasms', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoadjuvant Therapy', 'Neoplasm Grading', 'Positron Emission Tomography Computed Tomography', 'Prognosis', 'Retrospective Studies'] | 26,703,814 | [['M01.060.116'], ['M01.060.116.100'], ['E02.186.079.500', 'E02.319.164.500', 'E02.815.160.500'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gi2 alpha protein deficiency: a model of inflammatory bowel disease. | Mice deficient for the G protein subunit Gi2 alpha were obtained by gene targeting. They displayed a growth retardation that was apparent at 6 weeks of age. They subsequently developed diffuse colitis with clinical and histopathological features closely resembling those of ulcerative colitis in humans. Seven of 20 Gi2 ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Disease Models, Animal', 'GTP-Binding Proteins', 'Gene Targeting', 'Inflammatory Bowel Diseases', 'Mice', 'Mice, Transgenic', 'Molecular Sequence Data', 'T-Lymphocytes'] | 8,613,481 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['E05.393.335'], ['C06.405.205.731', 'C06.405.469.432'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Long-term outcomes of lumbar spinal stenosis: eight-year results of the Spine Patient Outcomes Research Trial (SPORT). | STUDY DESIGN: Randomized trial with a concurrent observational cohort study.OBJECTIVE: To compare 8-year outcomes of surgery with nonoperative care for symptomatic lumbar spinal stenosis.SUMMARY OF BACKGROUND DATA: Surgery for spinal stenosis has been shown to be more effective than nonoperative treatment during 4 year... | ['Aged', 'Disability Evaluation', 'Female', 'Humans', 'Laminectomy', 'Lost to Follow-Up', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Spinal Stenosis', 'Treatment Outcome'] | 25,569,524 | [['M01.060.116.100'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['E05.318.370.438'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C05.116.900.825'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study. | PURPOSE: Androgen receptor splice variant 7 (AR-V7) results in a truncated receptor, which leads to ligand-independent constitutive activation that is not inhibited by anti-androgen therapies, including abiraterone or enzalutamide. Given that previous reports suggested that circulating tumor cell (CTC) AR-V7 detection ... | ['Aged', 'Aged, 80 and over', 'Androstenes', 'Humans', 'Male', 'Middle Aged', 'Neoplastic Cells, Circulating', 'Phenylthiohydantoin', 'Predictive Value of Tests', 'Progression-Free Survival', 'Prospective Studies', 'Prostatic Neoplasms, Castration-Resistant', 'Protein Isoforms', 'Receptors, Androgen', 'Reproducibility ... | 30,865,549 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D04.210.500.054.079'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A11.642', 'C04.697.650.900', 'C23.550.727.650.900'], ['D03.383.129.308.432.555.868.650'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E01.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects on Pulmonary Vascular Mechanics of Two Different Lung-Protective Ventilation Strategies in an Experimental Model of Acute Respiratory Distress Syndrome. | OBJECTIVES: To compare the effects of two lung-protective ventilation strategies on pulmonary vascular mechanics in early acute respiratory distress syndrome.DESIGN: Experimental study.SETTING: University animal research laboratory.SUBJECTS: Twelve pigs (30.8 ± 2.5 kg).INTERVENTIONS: Acute respiratory distress syndrome... | ['Animals', 'Disease Models, Animal', 'Pulmonary Artery', 'Random Allocation', 'Respiration, Artificial', 'Respiratory Distress Syndrome', 'Respiratory Mechanics', 'Swine'] | 28,872,540 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A07.015.114.715'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['C08.381.840', 'C08.618.840'], ['G09.772.705.700'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dehydroepiandrosterone enhances influenza immunization in aged mice. | The effect of DHEA administration on the age-associated decline in immunity against influenza vaccine was studied. Increased humoral response was observed in 16- and 24-month-old mice immunized by live A/PR/8/34 (H1N1) influenza virus following DHEA treatment (a single injection adjacent to immunization). Furthermore, ... | ['Aging', 'Animals', 'Antibodies, Viral', 'Dehydroepiandrosterone', 'Female', 'Influenza Vaccines', 'Mice', 'Mice, Inbred C57BL', 'Orthomyxoviridae Infections'] | 8,597,470 | [['G07.345.124'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.952'], ['D20.215.894.899.302'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Repetitive naming and the detection of word retrieval deficits in the beginning reader. | The claim has been advanced that children with severe reading disability are generally deficient in word retrieval compared with normal readers. Support for the claim is based largely on studies of rapid naming of repetitively presented pictured objects or other nameable stimuli, a task which is apparently more sensiti... | ['Child', 'Color Perception', 'Humans', 'Memory', 'Mental Recall', 'Pattern Recognition, Visual', 'Reaction Time', 'Reading', 'Semantics', 'Verbal Learning'] | 4,092,487 | [['M01.060.406'], ['F02.463.593.932.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['L01.559.423.557'], ['L01.559.598.745'], ['F02.463.425.952']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Tuberculous meningitis in children in the Western Cape. Epidemiology and outcome. | The incidence of tuberculous meningitis in children was determined using hospital records as well as local authority notifications. One hundred and eighty-five cases occurred over a 3-year period. The age-specific incidence in the 0-14-year-old group was 7,5/100 000. In only 28 cases was the disease at an early stage w... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Prognosis', 'South Africa', 'Time Factors', 'Tuberculosis, Meningeal'] | 4,012,506 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.789'], ['Z01.058.290.175.735'], ['G01.910.857'], ['C01.150.252.223.500.937', 'C01.150.252.223.850.800', 'C01.150.252.410.040.552.846.570.600', 'C01.207.180.500.937', 'C01.207.180.850.800', 'C1... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Nitric oxide release from normal and dysfunctional endothelium. | The endothelium plays a critical role in maintaining vascular tone by releasing vasoconstrictor and vasodilator substances. Endothelium - derived nitric oxide (NO) is a vasodilator rapidly inactivated by superoxide (O2-) found in significant quantities. The porphyrinic sensor (0.5-8 microm diameter) and chemiluminescen... | ['Animals', 'Cells, Cultured', 'Cholesterol, LDL', 'Dose-Response Relationship, Drug', 'Endothelium, Vascular', 'Heart Ventricles', 'Humans', 'Hypertension', 'In Vitro Techniques', 'Luminescent Measurements', 'Male', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Organ Preservation', 'Porphyrins', 'Rabbits', 'Rats', 'Rats, ... | 10,639,008 | [['B01.050'], ['A11.251'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['G07.690.773.875', 'G07.690.936.500'], ['A07.015.700.500', 'A10.272.491.355'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.481'], ['E05.196.712.516']... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A case of bilateral lesions in the temporal convexity: attempt to define symptoms]. | The case is reported of a boy aged 15 who suffered a bilateral lesion of the temporal convexity after a brain traumatism; he died 5 years later and the symptoms during that period are described. The clinical picture is adequately described neither under the title of dementia, nor under that of aphasia. The concept of a... | ['Adolescent', 'Apraxias', 'Brain Injuries', 'Brain Mapping', 'Echolalia', 'Humans', 'Male', 'Memory Disorders', 'Psycholinguistics', 'Syndrome', 'Temporal Lobe'] | 954,450 | [['M01.060.057'], ['C10.597.606.881.350', 'C23.888.592.604.882.350', 'F01.700.875.350'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C10.597.606.150.500.800.300', 'C23.888.592.604.150.500.800.300'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A non-surgical technique for the transcervical administration of physiological and pharmacological agents into rat uteri. | A technique for the instillation of solutions into the rat uterine lumen is described. The method has been tested by following the receptor depletion/replenishment cycle after oestradiol injection and by checking on the stoichiometry of hormone/receptor translocation from the cytoplasmic compartment into the nucleus. B... | ['Animals', 'Cell Nucleus', 'Centrifugation, Density Gradient', 'Cytoplasm', 'Electrophoresis, Agar Gel', 'Estradiol', 'Female', 'Injections', 'Radioimmunoassay', 'Rats', 'Rats, Inbred Strains', 'Receptors, Estradiol', 'Receptors, Estrogen', 'Uterus'] | 6,857,751 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.181.724.336', 'E05.196.941.336'], ['A11.284.430.214'], ['E05.196.401.153', 'E05.301.300.100'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.319.267.530'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['B01.050.150.900... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beta-lipotropin-like immunoreactivity in intraglandular colloid from pituitary intermediate lobe cells. | The aim of this paper is the identification of beta-lipotropin (beta/LPH) as a peptide present in intraglandular colloid (the holocrine secretion of cells in the marginal half of the bovine pituitary intermediate lobe). beta/LPH, although not an opioid peptide itself, contains the peptide beta-endorphin. The methodolog... | ['Animals', 'Antibody Specificity', 'Cattle', 'Colloids', 'Pituitary Gland', 'Radioimmunoassay', 'beta-Endorphin', 'beta-Lipotropin'] | 2,977,325 | [['B01.050'], ['G12.100'], ['B01.050.150.900.649.313.500.380.271'], ['D20.280', 'D26.255.165'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.200.317.357.352.435.500', 'A08.713.357.750'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['D06.472.699.327.935.239', 'D06.472... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Infectious bovine rhinotracheitis outbreak on a mostly BHV-1 free farm can result in great damage]. | In a suckler herd with 110 cows (without young stock born in 2003) 5 cows died within 10 days, 6 calves were born dead prematurely and 5 calves were born alive but prematurely. The diagnosis BHV1-infection was based on clinical symptoms and confirmed with PCR. The clinical signs, diagnostic methods, therapy, risk-analy... | ['Animals', 'Cattle', 'Disease Outbreaks', 'Female', 'Herpesvirus 1, Bovine', 'Infectious Bovine Rhinotracheitis', 'Male', 'Netherlands', 'Polymerase Chain Reaction', 'Risk Management'] | 14,582,321 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['N06.850.290'], ['B04.280.382.100.900.400'], ['C01.925.256.466.488', 'C22.196.429'], ['Z01.542.651'], ['E05.393.620.500'], ['N03.219.463.800', 'N04.452.871']] | ['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Psychodynamics of neurotically-induced kleptomania]. | With a detailed case report of a patient suffering from kleptomania with neurotic causes, we are trying to obtain more detailed information about such patients' psychodynamics. The case history is preceded by a discussion of the concept of kleptomania. We give a list of the descriptive-empirical papers which prove that... | ['Adult', 'Crisis Intervention', 'Disruptive, Impulse Control, and Conduct Disorders', 'Drive', 'Humans', 'Male', 'Neurotic Disorders', 'Object Attachment', 'Psychoanalytic Theory', 'Psychoanalytic Therapy'] | 3,737,784 | [['M01.060.116'], ['F04.754.252'], ['F03.250'], ['F01.658.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.550', 'F03.650'], ['F02.739.794.624'], ['F02.739.794'], ['F04.754.709']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antibody response of humans to the circumsporozoite protein of Plasmodium vivax. | We studied the interaction of sera from residents of an area in northern Peru where vivax malaria is endemic with four recombinant DNA-derived circumsporozoite (CS) proteins of Plasmodium vivax. The antigens used in the enzyme-linked immunosorbent assay included one Escherichia coli-produced and three Saccharomyces cer... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Amino Acid Sequence', 'Animals', 'Antibodies, Protozoan', 'Antibody Specificity', 'Antigens, Protozoan', 'Child', 'Child, Preschool', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoglobulin G', 'Infant', 'Malaria', 'Middle Aged', 'Molecular Sequence Data', 'P... | 1,855,998 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['G12.100'], ['D23.050.293'], ['M01.060.406'], ['M01.060.406.448'], ['E05.478.566.350.1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
[Clinical processes in a high resolution clinic of specialist outpatient clinics]. | OBJECTIVES: The high resolution clinic (HRC) is an outpatient care process by which treatment and diagnosis are established, recorded, and completed in a single day. The aim of this study was to assess the extent to which patients with medical conditions may benefit from a single consultation system.MATERIAL AND METHOD... | ['Ambulatory Care', 'Ambulatory Care Facilities', 'Delivery of Health Care', 'Efficiency, Organizational', 'Female', 'Humans', 'Male', 'Middle Aged'] | 27,793,461 | [['E02.760.106', 'N02.421.585.106'], ['N02.278.035'], ['N04.590.374', 'N05.300'], ['N04.452.209.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Iron deposits in the central nervous system of SJL mice with experimental allergic encephalomyelitis. | Iron has been proposed to promote oxidative tissue damage in multiple sclerosis (MS). In order to gain insights about how iron gets processed during MS, the deposition of iron was investigated in the CNS of mice with experimental allergic encephalomyelitis (EAE), which is a commonly used animal model of MS. Control mic... | ['Animals', 'Astrocytes', 'Brain', 'Central Nervous System', 'Disease Models, Animal', 'Encephalomyelitis, Autoimmune, Experimental', 'Erythrocytes', 'Extravasation of Diagnostic and Therapeutic Materials', 'Female', 'Glial Fibrillary Acidic Protein', 'Immunohistochemistry', 'Iron', 'Macrophages', 'Mice', 'Oligodendrog... | 9,870,713 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['A08.186'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.550.340', 'C26.371'], ['D05... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical treatment of habitual luxation of the shoulder joint using the Dickson-O'Dell method. Our modification]. | The authors have presented their experience in the treatment of 40 patients with habitual dislocation of the shoulder joints using the method of Dickson-O'Dell during a period of 10 years. They have compared their results with results obtained by other methods and consider their modification as the method of choice on ... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Male', 'Methods', 'Middle Aged', 'Recurrence', 'Shoulder Dislocation'] | 2,609,504 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['C23.550.291.937'], ['C05.550.518.750', 'C26.289.750', 'C26.803.125']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Circulating nucleosomes are associated with mortality in pediatric acute respiratory distress syndrome. | Mechanisms underlying pediatric acute respiratory distress syndrome (PARDS) are poorly understood. The recent implication of circulating nucleosomes as pathogenic in sepsis and trauma-associated ARDS in adults led us to investigate the significance of nucleosomes in PARDS. We conducted a prospective, observational stud... | ['Biomarkers', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Nucleosomes', 'Prospective Studies', 'ROC Curve', 'Respiratory Distress Syndrome', 'Survival Analysis'] | 27,130,528 | [['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A11.284.430.106.279.345.190.160.180.625', 'D12.776.664.224.550', 'G05.360.160.180.625'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.370.800.75... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Human fetal breathing movements: basic analysis and clinical relationship to fetal well-being (author's transl)]. | By means of real time B-scan, human fetal breathing movements (FBM) was basically and clinically investigated on 244 observations in 215 pregnancies. The results obtained were as follows. (1) FBM was frequently observed during active sleep in which FHR variability and fetal movement increased. (2) The incidence of FBM ... | ['Blood Glucose', 'Female', 'Fetal Distress', 'Fetal Heart', 'Fetal Monitoring', 'Fetus', 'Humans', 'Maternal-Fetal Exchange', 'Pregnancy', 'Pregnancy Trimester, Third', 'Respiration'] | 7,234,348 | [['D09.947.875.359.448.500'], ['C23.888.380'], ['A07.541.278', 'A16.378.303'], ['E01.370.378.230', 'E01.370.520.230'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.455'], ['G08.686.784.769'], ['G08.686.707.520'], ['G09.772.705']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Facial elephantiasis neurofibromatosa--excision and skin graft. | A case of left facial elephantiasis neurofibromatosa was treated with near-total excision and skin graft. Results were favorable. Repositioning of canthal ligaments, preserving part of relatively normal masseter muscle and primary nasal reconstruction with forehead flap were performed. The skin graft over the myxomatou... | ['Adult', 'Elephantiasis', 'Face', 'Facial Neoplasms', 'Humans', 'Lymphedema', 'Male', 'Neurofibromatosis 1', 'Skin Transplantation', 'Surgery, Plastic'] | 2,516,422 | [['M01.060.116'], ['C15.604.496.320'], ['A01.456.505'], ['C04.588.443.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604.496'], ['C04.557.580.600.580.590.650', 'C04.700.631.650', 'C10.562.600.500', 'C10.574.500.549.400', 'C10.668.829.675', 'C16.320.400.560.400', 'C16.320.700.633.650'], ['E02.095.147.725.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of different exercise modalities plus a hypocaloric diet on inflammation markers in overweight patients: a randomised trial. | BACKGROUND & AIMS: Inflammation markers (IM) have been associated with the development of chronic diseases. This study compares the effects on IM of three exercise programs combined with a hypocaloric diet.METHODS: 119 overweight participants (73 women, 46 men) aged 18-50 years were randomised into four treatment group... | ['Adolescent', 'Adult', 'Biomarkers', 'C-Reactive Protein', 'Caloric Restriction', 'Energy Intake', 'Female', 'Humans', 'Inflammation', 'Interleukin-6', 'Linear Models', 'Male', 'Middle Aged', 'Overweight', 'Physical Endurance', 'Resistance Training', 'Tumor Necrosis Factor-alpha', 'Young Adult'] | 23,177,481 | [['M01.060.057'], ['M01.060.116'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E02.642.249.200', 'G07.203.650.240.340.150'], ['G07.203.650.240.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.37... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Does amiodarone influence early mortality in heart transplantation? | The use of amiodarone before transplantation has been linked to an increased number of complications, acute graft failures, and early mortality after a heart graft. We undertook a retrospective, descriptive, case-controlled study involving early mortality and acute graft failure. The 396 consecutive patients included 2... | ['Amiodarone', 'Anti-Arrhythmia Agents', 'Heart Transplantation', 'Humans', 'Multivariate Analysis', 'Patient Selection', 'Survival Analysis', 'Ventricular Dysfunction, Left'] | 17,097,993 | [['D03.633.100.127.075'], ['D27.505.954.411.097'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E05.581.500.653', 'N04.590.731'], ['E05.318.740.998', 'N05.715.360.750.795', 'N0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging. | The neuropeptide PDF is released by sixteen clock neurons in Drosophila and helps maintain circadian activity rhythms by coordinating a network of approximately 150 neuronal clocks. Whether PDF acts directly on elements of this neural network remains unknown. We address this question by adapting Epac1-camps, a genetica... | ['Animals', 'Animals, Genetically Modified', 'Behavior, Animal', 'Brain', 'Circadian Rhythm', 'Colforsin', 'Computer Systems', 'Cyclic AMP', 'Diagnostic Imaging', 'Dose-Response Relationship, Drug', 'Drosophila', 'Drosophila Proteins', 'Gene Expression Regulation', 'Insect Hormones', 'Luminescent Proteins', 'Motor Acti... | 18,439,407 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['F01.145.113'], ['A08.186.211'], ['G07.180.562.190'], ['D02.455.849.291.300'], ['L01.224.230'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['E01.370.350'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.500.131.... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pediatric faculty members' attitudes about part-time faculty positions and policies to support part-time faculty: a study at one medical center. | PURPOSE: To examine pediatric faculty members' attitudes about part-time faculty positions and policies to support part-time faculty.METHOD: In 2001, an anonymous 26-item questionnaire assessing attitudes about part-time faculty was mailed to all 441 faculty members of Cincinnati Children's Hospital Medical Center. Mul... | ['Adult', 'Age Factors', 'Attitude of Health Personnel', 'Career Choice', 'Career Mobility', 'Faculty, Medical', 'Female', 'Humans', 'Job Satisfaction', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Organizational Policy', 'Pediatrics', 'Personnel Staffing and Scheduling', 'Physicians, Women', 'Sex Factors', 'Survey... | 16,186,613 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.100.050', 'N05.300.100'], ['F02.463.785.373.346.400'], ['N01.824.245.175', 'N01.824.547.330'], ['M01.526.485.375', 'M01.526.702.250.373', 'N02.360.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['M01.060.116.630'], ['E05.318.7... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Ter94 ATPase complex targets k11-linked ubiquitinated ci to proteasomes for partial degradation. | The Cubitus interruptus (Ci)/Gli family of transcription factors can be degraded either completely or partially from a full-length form (Ci155/Gli(FL)) to a truncated repressor (Ci75/Gli(R)) by proteasomes to mediate Hedgehog (Hh) signaling. The mechanism by which proteasomes distinguish ubiquitinated Ci/Gli to carry o... | ['Adenosine Triphosphatases', 'Animals', 'Carrier Proteins', 'Cell Cycle Proteins', 'Cells, Cultured', 'Cullin Proteins', 'DNA-Binding Proteins', 'Drosophila Proteins', 'Drosophila melanogaster', 'Hedgehog Proteins', 'Intracellular Signaling Peptides and Proteins', 'Proteasome Endopeptidase Complex', 'Protein Binding',... | 23,747,190 | [['D08.811.277.040.025'], ['B01.050'], ['D12.776.157'], ['D12.776.167'], ['A11.251'], ['D08.811.464.938.750.750.500', 'D12.776.167.175'], ['D12.776.260'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D12.644.276.671', 'D12.776.467.671', 'D23.529.671'], ['D12.644.360', 'D12.776.476'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Significant Association Between Low Mitochondrial DNA Content in Peripheral Blood Leukocytes and Ischemic Stroke. | BACKGROUND: Cumulative evidence has shown that low mitochondrial DNA (mtDNA) content is related to elevated oxidative stress and atherosclerosis, which play important roles in ischemic stroke. The objective of this study was to explore the association between mtDNA content in peripheral blood leukocytes and ischemic st... | ['Biomarkers', 'Brain Ischemia', 'Case-Control Studies', 'DNA, Mitochondrial', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Leukocytes', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Mitochondria', 'Oxidative Stress', 'Real-Time Polymerase Chain Reaction', 'Tomography, X-Ray Computed'] | 29,151,031 | [['D23.101'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D13.444.308.283.225'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Allergic contact dermatitis to underwear elastic. Chemically transformed by laundry bleach. | Six subjects, allergic to the elastic in their undergarments, were patch test-negative to the rubber components and new elastic from the suppliers. However, washing the rubber with sodium hypochlorite gave the subjects allergic responses due to the effect of bleach on the rubber accelerator, zinc dibenzyldithiocarbamat... | ['Allergens', 'Carbamates', 'Chromatography, Gas', 'Clinical Trials as Topic', 'Clothing', 'Dermatitis, Atopic', 'Dermatitis, Contact', 'Drug Interactions', 'Humans', 'Laundering', 'Male', 'Mass Spectrometry', 'Patch Tests', 'Rubber', 'Sodium Hypochlorite', 'Zinc'] | 1,093,480 | [['D23.050.063'], ['D02.241.081.251'], ['E05.196.181.349'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['J01.637.215'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['C17.800.174.255', 'C17.800.815.255'], ['G07.690.773.968'], ['B01.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Structural and electrical ventricular remodeling in rat acute myocarditis and subsequent heart failure. | OBJECTIVE: We reported that experimental autoimmune myocarditis (EAM) rats showed dramatic changes in ventricular action potential and enhanced arrhythmogenicity in the acute phase, but mechanisms for this are still unclear. To investigate the mechanisms of cardiac remodeling in acute myocarditis and subsequent heart f... | ['Acute Disease', 'Animals', 'Electrophysiology', 'Heart Failure', 'Heart Ventricles', 'Hemodynamics', 'Ion Channels', 'Male', 'Myocarditis', 'Organ Size', 'RNA, Messenger', 'Rats', 'Rats, Inbred Lew', 'Reverse Transcriptase Polymerase Chain Reaction', 'Ventricular Remodeling'] | 15,306,225 | [['C23.550.291.125'], ['B01.050'], ['H01.158.344.528', 'H01.158.782.236'], ['C14.280.434'], ['A07.541.560'], ['G09.330.380'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['C14.280.238.625'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['D13.444.735.54... | ['Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
In situ metathesis ionic liquid formation dispersive liquid-liquid microextraction for copper determination in water samples by electrothermal atomic absorption spectrometry. | In situ synthesis of ionic liquid extractant for dispersive liquid-liquid microextraction (in situ IL DLLME) combined with electrothermal atomic absorption spectrometry (ET AAS) for determination of copper in water samples was developed. Analytical signals were obtained without the back-extraction of copper from the IL... | ['Cations, Divalent', 'Copper', 'Graphite', 'Hydrogen-Ion Concentration', 'Imidazoles', 'Imides', 'Ionic Liquids', 'Limit of Detection', 'Liquid Phase Microextraction', 'Reproducibility of Results', 'Solvents', 'Spectrophotometry, Atomic', 'Water Pollutants, Chemical'] | 24,054,576 | [['D01.248.497.300.333'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D01.268.150.300', 'D01.578.300'], ['G02.300'], ['D03.383.129.308'], ['D02.478'], ['D27.720.844.500'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.196.155.650.500'], ['E05.318.370.725', 'E05.33... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Pregnancy and thrombophilia in women with congenital deficit of antithrombin III, protein C, protein S or plasminogen: analysis of 39 cases]. | BACKGROUND: Pregnancy, delivery and puerperium are situations which increment the risk of thromboembolic complications in women who are carriers of congenital heterozygotic deficits of type I antithrombin III (ATIII), protein C (PC) or protein S (PS). The aim of this study was to analyze the experience of the authors a... | ['Adult', 'Antithrombin III Deficiency', 'Female', 'Humans', 'Metabolism, Inborn Errors', 'Middle Aged', 'Plasminogen', 'Pregnancy', 'Pregnancy Complications', 'Protein C Deficiency', 'Protein S Deficiency', 'Thrombosis'] | 8,429,723 | [['M01.060.116'], ['C15.378.100.100.075', 'C15.378.147.150', 'C15.378.925.075', 'C16.320.099.075'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565', 'C18.452.648'], ['M01.060.116.630'], ['D08.622.610', 'D12.776.124.790.223.580', 'D12.776.377.715.182.580', 'D12.776.811.243.610'], ['G08.686.784.769'], ['C... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuroendocrine effects of d-fenfluramine and bromocriptine following repeated smoked cocaine in humans. | To study the consequences of repeated smoked cocaine use on central serotonergic and dopaminergic function, the effects of d-fenfluramine (d-FEN) and bromocriptine on plasma hormones were determined at three time-points following repeated cocaine self-administration under carefully controlled conditions. In a 20-day in... | ['Adult', 'Analysis of Variance', 'Bromocriptine', 'Crack Cocaine', 'Fenfluramine', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Motivation', 'Prolactin', 'Self Administration', 'Substance Withdrawal Syndrome', 'Substance-Related Disorders', 'Time Factors'] | 11,470,342 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['D02.145.074.722.388.250', 'D03.132.889.354.250', 'D03.605.084.500.722.388.250', 'D03.605.869.388.250', 'D26.878.250'], ['D02.092.471.683.467'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prediction of novel archaeal enzymes from sequence-derived features. | The completely sequenced archaeal genomes potentially encode, among their many functionally uncharacterized genes, novel enzymes of biotechnological interest. We have developed a prediction method for detection and classification of enzymes from sequence alone (available at http://www.cbs.dtu.dk/services/ArchaeaFun/). ... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Archaea', 'Computational Biology', 'Enzymes', 'Glycosylation', 'Neural Networks, Computer', 'Phylogeny', 'Protein Structure, Secondary', 'Structure-Activity Relationship'] | 12,441,387 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B02'], ['H01.158.273.180', 'L01.313.124'], ['D08.811'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['G17.485', 'L01.224.050.375.605'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.570.820.709.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Strategies to promote better access to over the counter products for oral health in Europe: a Delphi survey. | OBJECTIVES: 'Over The Counter' (OTC) is a pharmaceutical product or medicine whose distribution or the administration does not require medical authorisation, and which can be used by consumers on their own initiative. This can be to prevent, relieve or treat symptoms or moderate pathologies and whose use, under the for... | ['Attitude of Health Personnel', 'Delphi Technique', 'Europe', 'Health Services Accessibility', 'Humans', 'Nonprescription Drugs', 'Oral Health', 'Self Medication', 'Surveys and Questionnaires'] | 19,998,664 | [['F01.100.050', 'N05.300.100'], ['L01.906.197'], ['Z01.542'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.530'], ['N01.400.535'], ['E02.319.900', 'E02.900.900'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Solvent oriented hobbies and the risk of systemic sclerosis. | OBJECTIVE: To examine whether those participating in solvent oriented hobbies (SOH) are at greater risk of developing systemic sclerosis (SSc), and if the association is modified by the presence of the anti-Scl70 antibody.METHODS: Patients with SSc and controls were recruited from a university hospital rheumatology cli... | ['Female', 'Hobbies', 'Humans', 'Male', 'Occupational Exposure', 'Risk Factors', 'Scleroderma, Systemic', 'Solvents'] | 10,555,893 | [['I03.450.642.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['C17.300.799', 'C17.800.784'], ['D27.720.844']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Utility of thromboelastography in managing acquired Factor VIII inhibitor associated massive haemorrhage. | Disorders of clotting and coagulation are common in the intensive care unit. Diagnosis, treatment and monitoring of these disorders are traditionally based on conventional coagulation tests such as activated partial thromboplastin time (APTT) and international normalised ratio (INR). We present here a patient who devel... | ['Antifibrinolytic Agents', 'Blood Coagulation Factors', 'Blood Transfusion', 'Endometrial Neoplasms', 'Factor VIIa', 'Female', 'Follow-Up Studies', 'Hematoma', 'Hemophilia A', 'Humans', 'Middle Aged', 'Partial Thromboplastin Time', 'Postoperative Hemorrhage', 'Radiography, Abdominal', 'Recombinant Proteins', 'Renal In... | 24,180,723 | [['D27.505.519.421.500', 'D27.505.954.502.270.463.091'], ['D12.776.124.125', 'D23.119'], ['E02.095.135'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['D08.811.277.656.300.760.300', 'D08.811.277.656.959.350.300', 'D12.776.124.125.325.300', 'D23.119.325.300'], ['E05.318.372.500.750... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A 15-year-old girl with a large pericardial effusion. | Pericarditis is a rare manifestation of tuberculosis and can be fatal. We describe a 15-year-old girl admitted for a large pericardial effusion. Subxiphoid pericardial biopsy was performed. Biopsy samples were positive for M. tuberculosis DNA by PCR, which confirmed the diagnosis of tuberculous pericarditis. | ['Adolescent', 'Antitubercular Agents', 'Female', 'Humans', 'Pericardial Effusion', 'Pericarditis, Tuberculous', 'Ultrasonography'] | 17,704,946 | [['M01.060.057'], ['D27.505.954.122.085.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.695'], ['C01.150.252.410.040.552.846.554.595', 'C01.190.750.595', 'C14.260.750.595', 'C14.280.720.801'], ['E01.370.350.850']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The cost effectiveness of preventing preterm delivery in twin pregnancies. | As an extension of previous work on the risk of prematurity in singletons and on the social cost of twin births, an analysis has been carried out into the cost effectiveness of preventing premature delivery in twin pregnancies. The cost of prevention is assessed in terms of early diagnosis through ultrasound screening ... | ['Cost-Benefit Analysis', 'Employment', 'Female', 'France', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Intensive Care Units, Neonatal', 'Obstetric Labor, Premature', 'Pregnancy', 'Pregnancy, Multiple', 'Prenatal Care', 'Twins'] | 2,128,160 | [['N03.219.151.125'], ['N01.824.245'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['N02.278.388.493.390.380'], ['C13.703.420.491'], ['G08.686.784.769'], ['G08.686.784.769.545'], ['E02.760.786', 'N02.421.143.620.704', 'N02.421.... | ['Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A randomized prospective controlled trial comparing the laryngeal tube suction disposable and the supreme laryngeal mask airway: the influence of head and neck position on oropharyngeal seal pressure. | BACKGROUND: The Laryngeal Tube Suction Disposable (LTS-D) and the Supreme Laryngeal Mask Airway (SLMA) are second generation supraglottic airway devices (SADs) with an added channel to allow gastric drainage. We studied the efficacy of these devices when using pressure controlled mechanical ventilation during general a... | ['Adult', 'Aged', 'Airway Management', 'Anesthesia, General', 'Equipment Design', 'Female', 'Fiber Optic Technology', 'Humans', 'Laryngeal Masks', 'Male', 'Middle Aged', 'Pharyngitis', 'Posture', 'Pressure', 'Prospective Studies', 'Respiration, Artificial', 'Single-Blind Method', 'Suction'] | 27,716,165 | [['M01.060.116'], ['M01.060.116.100'], ['E02.041'], ['E03.155.197'], ['E05.320'], ['H01.671.617.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500.475', 'E02.585.578.475', 'E05.497.578.475', 'E07.700.500.450', 'J01.637.708.560.782.450'], ['M01.060.116.630'], ['C01.748.561', 'C07.550.781', 'C08.730.56... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Developmental cognitive genetics: how psychology can inform genetics and vice versa. | Developmental neuropsychology is concerned with uncovering the underlying basis of developmental disorders such as specific language impairment (SLI), developmental dyslexia, and autistic disorder. Twin and family studies indicate that genetic influences play an important part in the aetiology of all of these disorders... | ['Child', 'Cognition', 'Genetics', 'Humans', 'Interdisciplinary Communication', 'Psychology', 'Twins'] | 16,769,616 | [['M01.060.406'], ['F02.463.188'], ['H01.158.273.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'], ['F04.096.628'], ['M01.438.873']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Safety, pharmacokinetics, and preliminary efficacy of E6201 in patients with advanced solid tumours, including melanoma: results of a phase 1 study. | BACKGROUND: This phase 1 first-in-human study aimed to determine the maximum-tolerated dose (MTD), dose-limiting toxicities, and safety of E6201, and to establish recommended dosing in patients with advanced solid tumours, expanded to advanced melanoma.METHODS: Part A (dose escalation): sequential cohorts received E620... | ['Adult', 'Aged', 'Aged, 80 and over', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Infusions, Intravenous', 'Lactones', 'Male', 'Maximum Tolerated Dose', 'Melanoma', 'Middle Aged', 'Neoplasms'] | 29,867,224 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['D02.540'], ['E05.940.481', 'G07.690.936.625'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.51... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A pharmacological approach to cellular mechanisms of PGI2-induced gastric cytoprotection on ethanol-induced gastric mucosal damage in rats. | The aims of this study were as follows: 1. to analyse the effects of drugs with different subcellular mechanisms on the PGI2-induced gastric cytoprotection in a non acid dependent (ethanol-induced) gastric ulcer model; 2. to identify the affinity and intrinsic activity curves on the PGI2-induced gastric cytoprotection;... | ['Animals', 'Drug Synergism', 'Epoprostenol', 'Ethanol', 'Female', 'Gastric Mucosa', 'Male', 'Rats', 'Rats, Inbred Strains', 'Stomach Ulcer'] | 2,512,766 | [['B01.050'], ['G07.690.773.968.477'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['D02.033.375'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['C06.405.469.275.800.849', 'C06.40... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The in vitro effect of paclitaxel on a LacZ-transfected malignant transitional cell line. | As bladder cancer is potentially lethal, the development of effective and tolerable therapeutic options is vital. In the present assay, we examined the in vitro effect of paclitaxel (Taxol) on the transitional cell carcinoma (TCC) cell line Hu1703He. Our model has several advantages over other in vitro models. The micr... | ['Antineoplastic Agents, Phytogenic', 'Carcinoma, Transitional Cell', 'Cell Cycle', 'Cell Growth Processes', 'Cell Line, Tumor', 'Cell Movement', 'Coculture Techniques', 'Flow Cytometry', 'Humans', 'Lac Operon', 'Neoplasm Invasiveness', 'Paclitaxel', 'Spheroids, Cellular', 'Transfection', 'Urinary Bladder', 'Urinary Bl... | 16,158,950 | [['D27.505.954.248.179'], ['C04.557.470.200.430'], ['G04.144'], ['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['E05.481.500.374'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350',... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of heat shock protein 70 in transport-stressed broiler pectoralis major muscle and its relationship with meat quality. | Omics research has indicated that heat shock protein 70 (HSP70) is a potential biomarker of meat quality. However, the specific changes and the potential role of HSP70 in postmortem meat quality development need to be further defined. In this study, Arbor Acres broiler chickens (n=126) were randomly categorized into th... | ['Animals', 'Chickens', 'Creatine Kinase', 'HSP70 Heat-Shock Proteins', 'Male', 'Meat', 'Pectoralis Muscles', 'Stress, Physiological', 'Transportation', 'Water'] | 28,077,200 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D08.811.913.696.640.150'], ['D12.776.580.216.375'], ['G07.203.300.600', 'J02.500.600'], ['A02.633.567.775'], ['G07.775'], ['J01.937'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Cohort study on the factors associated with survival post-cardiac arrest. | CONTEXT AND OBJECTIVE: Cardiac arrest is a common occurrence, and even with efficient emergency treatment, it is associated with a poor prognosis. Identification of predictors of survival after cardiopulmonary resuscitation may provide important information for the healthcare team and family. The aim of this study was ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Brazil', 'Cardiopulmonary Resuscitation', 'Epidemiologic Methods', 'Female', 'Heart Arrest', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Time Factors', 'Treatment Outcome', 'Young Adult'] | 26,760,123 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.757.176'], ['E02.365.647.110'], ['E05.318', 'N06.850.520'], ['C14.280.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Diagnostic and therapeutic pleuroscopy. Experience with 127 patients. | Experience with 127 pleuroscopies using the mediastinoscope is reviewed. The most frequent indications were pleural effusion (73 patients), pleural involvement by tumor (14), empyema (14), and recurrent pneumothorax (14). Findings were diagnostic in 119 of 127 patients (93.7 percent). Pleural metastases were found in 6... | ['Adolescent', 'Adult', 'Aged', 'Empyema', 'Endoscopes', 'Endoscopy', 'Female', 'Hemothorax', 'Humans', 'Lung Diseases', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Pleura', 'Pleural Effusion', 'Pleural Neoplasms', 'Pneumothorax', 'Talc', 'Thoracic Diseases'] | 7,428,455 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C01.830.305', 'C23.550.470.756.305'], ['E07.230.220', 'E07.858.240'], ['E01.370.388.250', 'E04.502.250'], ['C08.528.380', 'C23.550.414.904'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Emericella nidulans in a maxillary sinus fungal mass. | Sexual reproductive stages of fungi are very rarely found within mammalian tissues. We report here coexistence of cleistothecia associated with Emericella nidulans and its conidial state, Aspergillus nidulans, in a fungal mass which developed in a maxillary sinus. | ['Aged', 'Aspergillosis', 'Aspergillus nidulans', 'Female', 'Humans', 'Maxillary Sinus', 'Sinusitis', 'Spores, Fungal'] | 3,323,452 | [['M01.060.116.100'], ['C01.150.703.080'], ['B01.300.381.081.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.531.621.578'], ['C01.748.749', 'C08.460.692.752', 'C08.730.749', 'C09.603.692.752'], ['A11.870.710', 'A19.374.500', 'B05.775.710']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Late results and economic aspects of the treatment of skin cancer with impulse laser irradiation]. | The authors analyze results of the treatment of 1261 patients with carcinoma of the skin and recurrent basiliomas arising after other methods of treatment. The patients were observed within the period of from 1 to 11 years. Recurrences were detected in 1.9% of the patients subjected to laser therapy. Great curative and... | ['Adult', 'Carcinoma, Basal Cell', 'Carcinoma, Squamous Cell', 'Cost-Benefit Analysis', 'Female', 'Follow-Up Studies', 'Humans', 'Laser Therapy', 'Male', 'Skin Neoplasms', 'Time Factors'] | 6,419,432 | [['M01.060.116'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['N03.219.151.125'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['C04.588.805', '... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The carboxylesterase family exhibits C-terminal sequence diversity reflecting the presence or absence of endoplasmic-reticulum-retention sequences. | Resident proteins of the endoplasmic reticulum lumen are continuously retrieved from an early Golgi compartment by a receptor-mediated mechanism. The sorting or retention sequence on the endoplasmic reticulum proteins is located at the C-terminus and was initially shown to be the tetrapeptide KDEL in mammalian cells an... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Carboxylesterase', 'Carboxylic Ester Hydrolases', 'Cell Line', 'Cloning, Molecular', 'DNA', 'Endoplasmic Reticulum', 'Gene Expression', 'Immunosorbent Techniques', 'Liver', 'Molecular Sequence Data', 'Mutagenesis', 'Polymerase Chain Reaction', 'Rats', 'Rats, Inbred S... | 1,606,962 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.277.352.100.100'], ['D08.811.277.352.100'], ['A11.251.210'], ['E05.393.220'], ['D13.444.308'], ['A11.284.430.214.190.875.248'], ['G05.297'], ['E05.478.566.380', 'E05.601.470.380'], ['A03.620'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Human alveolar macrophages: comparison of phagocytic ability, glucose utilization, and ultrastructure in smokers and nonsmokers. | Phagocytic ability, glucose utilization, and ultrastructural morphology were studied in human alveolar macrophages in smokers and nonsmokers. The macrophages were obtained by bronchopulmonary lavage and the studies were carried out in vitro in the absence of smoke. Phagocytic ability was measured as the decrease in the... | ['Adult', 'Carbon Dioxide', 'Cell Count', 'Cell Nucleus', 'Color', 'Cough', 'Endoplasmic Reticulum', 'Female', 'Glucose', 'Golgi Apparatus', 'Humans', 'Inclusion Bodies', 'Lysosomes', 'Macrophages', 'Male', 'Microscopy, Electron', 'Mitochondria', 'Phagocytosis', 'Plants, Toxic', 'Pulmonary Alveoli', 'Smoking', 'Spirome... | 4,319,967 | [['M01.060.116'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G01.590.540.199'], ['C08.618.248', 'C23.888.852.293'], ['A11.284.430.214.190.875.248'], ['D09.947.875.359.448'], ['A11.284.430.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
PGSB PlantsDB: updates to the database framework for comparative plant genome research. | PGSB (Plant Genome and Systems Biology: formerly MIPS) PlantsDB (http://pgsb.helmholtz-muenchen.de/plant/index.jsp) is a database framework for the comparative analysis and visualization of plant genome data. The resource has been updated with new data sets and types as well as specialized tools and interfaces to addre... | ['Databases, Genetic', 'Gene Expression', 'Genome, Plant', 'Genomics', 'Hordeum', 'Plants', 'Secale', 'Software', 'Triticum'] | 26,527,721 | [['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.297'], ['G05.360.340.365'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.650.940.800.575.912.250.822.481'], ['B01.650'], ['B01.650.940.800.575.912.250.822.857'], ['L01.224.900'], ['B01.650.940.800.575.912.250.822.918']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Clinical measurement of hearing aid insertion gain. | The probe microphone devised by Lauridsen & G?nthersen (1981) was tested in a clinical situation, and the results were compared with those obtained with a miniature electret microphone place in the ear canal (cf. Harford, 1980), and also with those obtained with the eardrum microphone on the acoustic manikin KEMAR. Goo... | ['Adult', 'Aged', 'Amplifiers, Electronic', 'Ear Canal', 'Female', 'Hearing Aids', 'Hearing Loss', 'Humans', 'Male', 'Methods', 'Middle Aged'] | 7,178,818 | [['M01.060.116'], ['M01.060.116.100'], ['E07.305.061'], ['A09.246.272.396'], ['E07.305.906.500', 'E07.814.458'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of vitamin E-coated dialysis membranes on anemia, nutrition and dyslipidemia status in hemodialysis patients: a meta-analysis. | BACKGROUND: This was controversial whether vitamin E-coated dialyzer therapy was beneficial for the complications associated with hemodialysis. Therefore, we performed this systematic review to evaluate the effects of vitamin E-coated dialyzer.METHODS: Related trials were searched from multiple electronic databases. We... | ['Anemia', 'Antioxidants', 'Coated Materials, Biocompatible', 'Dyslipidemias', 'Humans', 'Kidney Failure, Chronic', 'Membranes, Artificial', 'Nutritional Status', 'Outcome Assessment, Health Care', 'Randomized Controlled Trials as Topic', 'Renal Dialysis', 'Vitamin E'] | 25,585,953 | [['C15.378.071'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D25.130.420', 'J01.637.051.130.420'], ['C18.452.584.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G07.203.650.650'... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
The effect of glucocorticoids on the anxiolytic efficacy of buspirone. | RATIONALE: The serotonergic system and the hypothalamus-hypophysis-adrenocortical axis reciprocally influence each other. Therefore, the interaction between stress and serotonergic anxiolytics should be of major concern for both laboratory investigations and clinical treatment.OBJECTIVES: We have studied the effects of... | ['Adrenalectomy', 'Animals', 'Anti-Anxiety Agents', 'Anxiety', 'Behavior, Animal', 'Buspirone', 'Dose-Response Relationship, Drug', 'Glucocorticoids', 'Interpersonal Relations', 'Male', 'Motor Activity', 'Rats', 'Rats, Wistar', 'Stress, Psychological'] | 11,605,098 | [['E04.270.115'], ['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['F01.470.132'], ['F01.145.113'], ['D02.455.426.779.120', 'D03.383.606.210', 'D03.383.742.120', 'D04.711.120'], ['G07.690.773.875', 'G07.690.936.500'], ['D06.472.040.543', 'D27.505.696.399.472.488']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Response of [Ah] battery genes to compounds that protect against menadione toxicity. | We have studied the response of genes in the dioxin-inducible [Ah] battery to three compounds that protect mouse hepatoma cells (Hepa-1c7c7 wild-type, wt) against menadione toxicity. Pretreatment of wt cells with 25 microM 5,10-dihydroindenol[1,2-b]indole (DHII), 25 microM tert-butylhydroquinone (tBHO) or 10 microM men... | ['Aldehyde Dehydrogenase', 'Animals', 'Antioxidants', 'Cytochrome P-450 CYP1A2', 'Cytochrome P-450 Enzyme System', 'Enzyme Induction', 'Glucuronosyltransferase', 'Hydroquinones', 'Indoles', 'Mice', 'NAD(P)H Dehydrogenase (Quinone)', 'Oxidoreductases', 'RNA, Messenger', 'Receptors, Aryl Hydrocarbon', 'Transcription, Gen... | 8,615,869 | [['D08.811.682.657.163.249'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D08.244.453.005.443', 'D08.244.453.100.750', 'D08.811.682.690.708.170.010.443', 'D08.811.682.690.708.170.020.750', 'D12.776.422.220.453.010.443', 'D12.776.422.220.453.100.750'], ['D08.244.453', 'D08.811.682.690.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors associated with success of market authorisation applications for pharmaceutical drugs submitted to the European Medicines Agency. | PURPOSE: To identify factors associated with success of Market Authorisation Applications (MAAs) for pharmaceutical drugs submitted to the European Medicines Agency (EMEA), with an emphasis on the Scientific Advice (SA) given by the Committee for Human Medicinal Products (CHMP).METHODS: MAAs with a CHMP decision (outco... | ['Advisory Committees', 'Drug Approval', 'Drug Industry', 'Europe', 'Government Agencies', 'Humans', 'Legislation, Drug', 'Marketing', 'Pharmaceutical Preparations'] | 19,936,724 | [['N03.706.742.500'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['J01.576.655.750'], ['Z01.542'], ['I01.409.418', 'N03.540.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.605', 'N03.706.615.402'], ['J01.219.687'], ['D26']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Removal of volatile gasoline compounds by indoor potted plants studied by pixel-based fingerprinting analysis. | Indoor potted plants are able to remove volatile organic compounds (VOC) from air, but only few studies have investigated the removal of compounds in mixtures. Here, we present a non-targeted pixel-based fingerprinting analysis documenting the removal of a complex mixture of gasoline VOCs by Hedera helix under dynamic ... | ['Air Pollutants', 'Air Pollution, Indoor', 'Benzene Derivatives', 'Gasoline', 'Plants', 'Soil', 'Soil Microbiology', 'Volatile Organic Compounds'] | 30,640,005 | [['D27.888.284.101'], ['N06.850.460.100.080'], ['D02.455.426.559.389'], ['D20.345.630.540', 'N06.230.132.258.630.540'], ['B01.650'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['D02.974']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Endotoxin induces late increase in the production of pulmonary proinflammatory cytokines in murine lupus-like pristane-primed model [corrected]. | Lupus-like syndrome is characterized by multiple organ injuries including lungs and kidneys. Endotoxin induces a transiently intent systemic inflammatory response and indirectly transient acute lung injury in normal condition. However, whether endotoxin may trigger the persistent development of lung injury in chronic, ... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Capillary Permeability', 'Cells, Cultured', 'Cytokines', 'Disease Models, Animal', 'Endotoxins', 'Female', 'Interleukin-10', 'Interleukin-6', 'Lipopolysaccharides', 'Lung', 'Lupus Erythematosus, Systemic', 'Mice', 'Mice, Inbred ICR', 'Terpenes', 'Time Factors', 'Tumor Necros... | 16,681,036 | [['B01.050'], ['E05.927.100.500'], ['G03.143.330', 'G09.330.165'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D23.946.123.329'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['D12.644.276.374.465.224', 'D12.776.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The oncoproteins c-erb-B2, c-fos and the tumour suppressor protein p53 in human embryos and fetuses. | Oncoproteins and tumour-suppressor proteins are thought to possess an antagonistic function in the regulation of growth and differentiation processes during embryonic and fetal development. In contrast, in the adult, tumour growth is associated with the overexpression of oncoproteins or the malfunction of tumour-suppre... | ['Embryo, Mammalian', 'Embryonic and Fetal Development', 'Female', 'Fetus', 'Gestational Age', 'Humans', 'Immunohistochemistry', 'Kidney', 'Liver', 'Lung', 'Muscles', 'Pregnancy', 'Proto-Oncogene Proteins c-fos', 'Receptor, ErbB-2', 'Skin', 'Tumor Suppressor Protein p53'] | 9,108,200 | [['A16.254'], ['G07.345.500.325', 'G08.686.784.170'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cigarette smoke-induced failure of apoptosis resulting in enhanced neoplastic transformation in human bronchial epithelial cells. | The lack of apoptotic pathways may lead to undesirable cell survival and proliferation, which are recognized hallmarks of cancer. It is well known that exposure to cigarette smoke induces DNA lesions in pulmonary cells. At present, it is not fully elucidated whether these lesions are repaired to restore normal function... | ['Animals', 'Apoptosis', 'Bronchi', 'Cell Line', 'Cell Transformation, Neoplastic', 'DNA Methylation', 'Epithelial Cells', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Membrane Potential, Mitochondrial', 'Mice', 'Mice, Inbred BALB C', 'Neoplasms', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Respir... | 22,757,675 | [['B01.050'], ['G04.146.954.035'], ['A04.411.125'], ['A11.251.210'], ['C04.697.098.500', 'C23.550.727.098.500'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['A11.436'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.295.770.500', 'G04.580.550', 'G07.265.675.550'], ['B... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The carboxyl terminus of type VII collagen mediates antiparallel dimer formation and constitutes a new antigenic epitope for epidermolysis Bullosa acquisita autoantibodies. | Type VII collagen, the major component of anchoring fibrils, consists of a central collagenous triple-helical domain flanked by two noncollagenous domains, NC1 and NC2. The NC2 domain has been implicated in catalyzing the antiparallel dimer formation of type VII procollagen. In this study, we produced the entire 161 am... | ['Amino Acid Substitution', 'Autoantibodies', 'Binding Sites, Antibody', 'Cell Line', 'Collagen', 'Dimerization', 'Epidermolysis Bullosa Acquisita', 'Epitopes', 'Humans', 'Mutagenesis, Site-Directed', 'Peptide Fragments', 'Procollagen', 'Protein Structure, Secondary', 'Recombinant Fusion Proteins', 'Recombinant Protein... | 11,274,208 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['A11.251.210'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G02.206', 'G03.230'], ['C16.131.831.493.080... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii. | Apicomplexan parasites are the cause of numerous important human diseases including malaria and AIDS-associated opportunistic infections. Drug treatment for these diseases is not satisfactory and is threatened by resistance. The discovery of the apicoplast, a chloroplast-like organelle, presents drug targets unique to ... | ['Acetates', 'Acetyltransferases', 'Acyl Carrier Protein', 'Animals', 'Carbon Radioisotopes', 'Chloroplasts', 'Fatty Acid Synthase, Type II', 'Fatty Acids', 'Gene Expression Regulation', 'Gene Targeting', 'Humans', 'Mice', 'Multienzyme Complexes', 'Mutant Proteins', 'Parasites', 'Pyruvate Dehydrogenase Complex', 'Tetra... | 16,920,791 | [['D02.241.081.018', 'D10.251.400.045'], ['D08.811.913.050.134'], ['D12.776.157.050'], ['B01.050'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.284.430.214.190.875.700.140'], ['D05.500.562.444', 'D08.811.277.352.897.387.200', 'D08.811.520.241.300.287.200', 'D08.811.600.354', 'D08.811.682.047.82... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pediatric medial epicondyle fractures with intra-articular elbow incarceration. | BACKGROUND: Intra-articular incarceration of the epicondylar fragment occurs in 5-18 % of all cases of medial epicondyle fracture. It requires stable fixation to allow early motion, since elbow stiffness is the most common complication following medial epicondyle fracture. In this retrospective study, we report the cli... | ['Adolescent', 'Bone Screws', 'Child', 'Elbow Joint', 'Female', 'Fluoroscopy', 'Fracture Fixation, Internal', 'Humans', 'Humeral Fractures', 'Male', 'Postoperative Complications', 'Range of Motion, Articular', 'Retrospective Studies', 'Treatment Outcome'] | 25,062,665 | [['M01.060.057'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['M01.060.406'], ['A02.835.583.290'], ['E01.370.350.700.225'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.088.390', 'C26.404.500'], ['C23.550.767'], ['E01.370.600.700', 'G11.427.760'], ['E05.318... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Fournier's gangrene on ischial pressure ulcer: use of vacuum-assisted closure and therapeutic strategy]. | Vacuum-assisted closure (V.A.C.) was used in two paraplegic patients with Fournier's gangrene in a context of ischial pressure ulcer This type of dressing facilitated preparation of reconstruction. | ['Adult', 'Fournier Gangrene', 'Humans', 'Male', 'Middle Aged', 'Negative-Pressure Wound Therapy', 'Paraplegia', 'Reconstructive Surgical Procedures'] | 17,969,807 | [['M01.060.116'], ['C01.150.252.377', 'C12.294.229'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.309.610', 'E04.237.444', 'E04.987.550'], ['C10.597.622.669', 'C23.888.592.636.637'], ['E04.680']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Investigations of step-growth thiol-ene polymerizations for novel dental restoratives. | OBJECTIVES: The goal of this work was to investigate the feasibility of formulating novel dental restorative materials that utilize a step-growth thiol-ene photopolymerization. Particularly, we are aiming to significantly reduce the polymerization shrinkage and shrinkage stress while retaining adequate physical propert... | ['3-Mercaptopropionic Acid', 'Allyl Compounds', 'Bisphenol A-Glycidyl Methacrylate', 'Chemical Phenomena', 'Chemistry, Physical', 'Composite Resins', 'Dental Materials', 'Elasticity', 'Ethers', 'Ethylene Glycols', 'Feasibility Studies', 'Humans', 'Materials Testing', 'Pliability', 'Polyethylene Glycols', 'Polymers', 'P... | 16,046,231 | [['D02.241.081.751.080', 'D02.886.489.520'], ['D02.455.326.271.122'], ['D02.241.081.069.600.150', 'D02.455.426.559.389.657.100', 'D05.750.716.822.308.200', 'D25.339.816.500.200', 'D25.720.716.822.308.200', 'J01.637.051.339.816.500.200', 'J01.637.051.720.716.822.308.200'], ['G02'], ['H01.181.529'], ['D05.750.716.822.308... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Outcomes of endovascular management for complicated chronic type B aortic dissection: effect of the extent of stent graft coverage and anatomic properties of aortic dissection. | PURPOSE: To assess the effect of the extent of stent graft coverage and anatomic properties of aortic dissection on the outcomes of thoracic endovascular aortic repair (TEVAR) for complicated chronic type B aortic dissection (CCBAD) in terms of survival, reintervention, and false lumen thrombosis.MATERIALS AND METHODS:... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aneurysm, Dissecting', 'Aortic Aneurysm', 'Blood Vessel Prosthesis', 'Chronic Disease', 'Comorbidity', 'Disease-Free Survival', 'Endovascular Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prevalence', 'Republic of Korea', 'Retrospective S... | 23,932,416 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.050'], ['C14.907.055.239', 'C14.907.109.139'], ['E07.695.110'], ['C23.550.291.500'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Determination of the major dimensions of femoral implants using morphometrical data and principal component analysis. | This paper describes the work that leads to the establishment of a set of major parameters for the design of symmetrical prosthetic implants for the Asian population. In the study, 62 sets of femurs harvested from cadavers were used. The morphometrical data obtained are compared with known results and found to be in go... | ['Aged', 'Asian Continental Ancestry Group', 'Cadaver', 'European Continental Ancestry Group', 'Female', 'Femur', 'Humans', 'Knee Prosthesis', 'Male', 'Middle Aged', 'Prosthesis Design'] | 10,902,444 | [['M01.060.116.100'], ['M01.686.508.200'], ['C23.550.260.224'], ['M01.686.508.400'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400.410'], ['M01.060.116.630'], ['E05.320.550', 'E07.695.680']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lack of intrafamilial transmission of hepatitis C virus in family members of children with chronic hepatitis c infection. | Intrafamilial transmission of hepatitis C virus (HCV) was studied in family members of 44 children with chronic hepatitis C infection (index cases). There were 22 males and the mean age of all patients was 9.5 years (range, 1.5 to 16 years). Eleven index patients were multitransfused because of thalassemia major. Amino... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Disease Transmission, Infectious', 'Family Characteristics', 'Female', 'Hepatitis C', 'Hepatitis, Chronic', 'Humans', 'Infectious Disease Transmission, Vertical', 'Male', 'Risk Factors'] | 7,854,888 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.335'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['C06.552.380.350'], ['B01.050.1... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Telemedicine Use for Movement Disorders: A Global Survey. | BACKGROUND: Telemedicine is increasingly used to care for patients with movement disorders, but data regarding its global use are limited.INTRODUCTION: To obtain baseline international data about telemedicine use among movement disorder clinicians.METHODS: An online survey was sent to all 6,056 Movement Disorder Societ... | ['Attitude of Health Personnel', 'Electronic Mail', 'Global Health', 'Humans', 'Insurance, Health, Reimbursement', 'Movement Disorders', 'Patient Education as Topic', 'Quality of Health Care', 'Telemedicine', 'Videoconferencing'] | 29,565,764 | [['F01.100.050', 'N05.300.100'], ['L01.178.847.249', 'L01.559.423.906.377.333'], ['H02.403.371', 'N01.400.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.480', 'N03.219.521.710'], ['C10.228.662'], ['I02.233.332.500', 'N02.421.726.407.680'], ['N04.761', 'N05.715'], ['H02.403.840', 'L01.178.... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Relationship between the expression of the extracellular matrix genes SPARC, SPP1, FN1, ITGA5 and ITGAV and clinicopathological parameters of tumor progression and colorectal cancer dissemination. | OBJECTIVE: To evaluate the relationship between the expression of the extracellular matrix (ECM) genes SPARC, SPP1, FN1, ITGA5 and ITGAV and the histopathologic parameters of neoplastic progression and colorectal carcinoma (CRC) dissemination.METHODS: A retrospective study was conducted in 114 patients with stage I-IV ... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Colorectal Neoplasms', 'Female', 'Fibronectins', 'Follow-Up Studies', 'Humans', 'Immunoenzyme Techniques', 'Integrin alpha5', 'Integrin alphaV', 'Liver Neoplasms', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm In... | 23,128,103 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', ... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Infective endocarditis in patients receiving chronic hemodialysis: A 21-year observational cohort study in Denmark. | BACKGROUND: Chronic hemodialysis is a risk factor for invasive bacterial infections. We conducted a nationwide study of risk and mortality of infective endocarditis (IE) among patients undergoing chronic hemodialysis.METHODS: In this observational cohort study, patients with end-stage renal disease who initiated hemodi... | ['Adolescent', 'Adult', 'Aged', 'Arteriovenous Shunt, Surgical', 'Cohort Studies', 'Comorbidity', 'Denmark', 'Endocarditis', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Risk Factors'] | 27,914,498 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.035.087', 'E04.100.814.868.249'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['Z01.542.816.124'], ['C14.280.282'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Associations between perceived crisis mode work climate and poor information exchange within hospitals. | BACKGROUND: Because hospital units operating in crisis mode could create unsafe transitions of care due to miscommunication, our objective was to estimate associations between perceived crisis mode work climate and patient information exchange problems within hospitals.METHODS: Self-reported data from 247,140 hospital ... | ['Attitude of Health Personnel', 'Crew Resource Management, Healthcare', 'Health Information Exchange', 'Hospitals', 'Humans', 'Interprofessional Relations', 'Patient Safety', 'Perception', 'Personnel, Hospital', 'Surveys and Questionnaires', 'Workload'] | 25,491,237 | [['F01.100.050', 'N05.300.100'], ['N04.590.254'], ['E05.318.308.940.968.625.500.500', 'L01.313.500.500', 'L01.399.500.500'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['N06.850.135.060.075.399'], ['F02.463.593'], ['M01.526.485.740', 'N02.360.740'], ['E05.318.308.980', 'N05.7... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
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