Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Case-control inference of interaction between genetic and nongenetic risk factors under assumptions on their distribution. | In genetic association studies, there is increasing interest in understanding the joint effects of genetic and nongenetic factors. For rare diseases, the case-control study is a practical design, and logistic regression is the standard method of inference. However, the power to detect statistical interaction is a conce... | ['Case-Control Studies', 'Computer Simulation', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Humans', 'Likelihood Functions', 'Models, Genetic', 'Rare Diseases', 'Risk Factors'] | 17,474,879 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['L01.224.160'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Calcium binding by chick calretinin and rat calbindin D28k synthesised in bacteria. | Calretinin is a member of the EF-hand calcium-binding protein family, with a high similarity with calbindin D28k. The chick calretinin cDNA sequence was reconstructed in a M13 vector and transferred into an expression plasmid derived from the pET series. The calretinin gene was expressed in Escherichia coli and produce... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Calbindin 1', 'Calbindin 2', 'Calbindins', 'Calcium', 'Chemical Fractionation', 'Chickens', 'Chromatography', 'Culture Media', 'DNA', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Molecular Sequence Data', 'Plasmids', 'Rats', 'S100 Calcium Binding Prote... | 8,344,307 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157.125.090.124', 'D12.776.631.087'], ['D12.776.157.125.090.249'], ['D12.776.157.125.090'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.196.155'], ['B01.050.150.900.248.350.150... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Detection of epitopes in glycosaminoglycans immobilized on hydrophobic membranes. | Glycosaminoglycans (GAGs) are linear carbohydrate polymers expressed on all cell surfaces, and bind growth factors that recognize specific disaccharide sequences. Such sequences in the GAG chain are not genetically determined but may be assembled by the cell in response to environmental changes. GAGs are strongly hydro... | ['Animals', 'Antibodies, Monoclonal', 'Cattle', 'Chondroitin Sulfates', 'Dermatan Sulfate', 'Detergents', 'Epitopes', 'Glycosaminoglycans', 'Humans', 'Hydrogen-Ion Concentration', 'Membranes, Artificial', 'Osmolar Concentration', 'Swine'] | 11,317,939 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.500.380.271'], ['D09.698.373.200.300'], ['D09.698.373.200.380'], ['D27.720.877.265', 'J01.516.381'], ['D23.050.550'], ['D09.698.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Asthma, employment status, and disability among adults treated by pulmonary and allergy specialists. | STUDY OBJECTIVE: Identify risk factors for work disability among adults with asthma treated by pulmonary and allergy specialists.DESIGN: Cross-sectional survey, including retrospective work history data.PARTICIPANTS: Sixty-eight pulmonary and 16 allergy internal medicine subspecialists maintaining a registry of patient... | ['Adult', 'Asthma', 'Cross-Sectional Studies', 'Disability Evaluation', 'Female', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Occupational Health', 'Pulmonary Medicine', 'Risk Factors', 'Severity of Illness Index', 'Socioeconomic Factors'] | 8,617,077 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.400'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N01.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Direct fluorometric detection of paramagnetic and heavy metal ions at sub-amol level using an aromatic polyaminocarboxylate by CZE: Combination of pre- and on-capillary complexation technique. | The low sensitivity of simple CZE for detecting metal ions is a long-standing problem even when an LIF detection system is employed. We have successfully achieved an ultrasensitive CE-LIF using a simple CZE mode (typical detection limit: 10(-11)-10(-10) mol/dm(3)). Both the design of a newly synthesized ligand and the ... | ['Calcium', 'Edetic Acid', 'Electrophoresis, Capillary', 'Environment', 'Fluoresceins', 'Fluorometry', 'Ions', 'Ligands', 'Magnetics', 'Metals, Heavy', 'Sensitivity and Specificity'] | 17,577,884 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['E05.196.401.190', 'E05.301.300.190'], ['G16.500.275', 'N06.230'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['E05.196.712.516.600'], ['D01.248.497'], ['D27.720.470.480'], ['H01.671.493'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
An acyl-coenzyme A carboxylase encoding gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230. | Analysis of a region of chromosomal DNA lying between jadR1 and jadI in the gene cluster for jadomycin biosynthesis in Streptomyces venezuelae ISP5230 detected an ORF encoding 584 amino acids similar in sequence to the biotin carboxylase (BC) and biotin carboxyl carrier protein (BCCP) components of acyl-coenzyme A carb... | ['Amino Acid Sequence', 'Carbon-Carbon Ligases', 'Gene Expression Regulation, Bacterial', 'Isoquinolines', 'Molecular Sequence Data', 'Sequence Alignment', 'Streptomyces'] | 10,784,049 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.464.257'], ['G05.308.300'], ['D03.633.100.531'], ['L01.453.245.667'], ['E05.393.751'], ['B03.300.390.400.810.768', 'B03.510.024.997.775', 'B03.510.415.400.810.768', 'B03.510.460.410.810.768']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Quality of life of patients on treatment for latent tuberculosis infection: a mixed-method study in Stockholm, Sweden. | BACKGROUND: Unlike active tuberculosis, latent tuberculosis infection (LTBI) is asymptomatic and often considered not to affect the health-related quality of life (HRQoL) of patients. However, being diagnosed with and treated for LTBI can be associated with adverse clinical evens such side effects of treatment as well ... | ['Adult', 'Anxiety', 'Cross-Sectional Studies', 'Depression', 'Female', 'Humans', 'Latent Tuberculosis', 'Male', 'Middle Aged', 'Qualitative Research', 'Quality of Life', 'Surveys and Questionnaires', 'Sweden'] | 31,651,339 | [['M01.060.116'], ['F01.470.132'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.040.552.846.122', 'C01.550.500'], ['M01.060.116.630'], ['H01.770.644.241.850'], ['I01.800', 'K01.752.400.750', 'N06.85... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Attenuated ventilatory responses to hypercapnia and hypoxia in assisted breath-hold drivers (Funado). | The steady-state ventilatory responses to hypercapnia and hypoxia in 7 assisted breath-hold divers (Funado) were compared with those in 7 normal sedentary controls. Ventilatory response to hypercapnia was measured from the slope of the hyperoxic VN-PETCO2 line, where VN was normalized minute ventilation using the allom... | ['Adult', 'Diving', 'Humans', 'Hypercapnia', 'Hypoxia', 'Male', 'Mathematics', 'Middle Aged', 'Respiration'] | 7,131,933 | [['M01.060.116'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['C23.888.852.079'], ['H01.548'], ['M01.060.116.630'], ['G09.772.705']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Polyoxometalates--potent and selective ecto-nucleotidase inhibitors. | Polyoxometalates (POMs) are inorganic cluster metal complexes that possess versatile biological activities, including antibacterial, anticancer, antidiabetic, and antiviral effects. Their mechanisms of action at the molecular level are largely unknown. However, it has been suggested that the inhibition of several enzym... | ['Adenosine Triphosphatases', 'Animals', 'Cell Line, Tumor', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Humans', 'Insecta', 'Mice', 'Phosphoric Diester Hydrolases', 'Sf9 Cells', 'Tungsten Compounds'] | 25,449,596 | [['D08.811.277.040.025'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.131.617'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.277.352.640'], ['A11.251.210.891'], ['D01.940']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The challenges of providing rehabilitation for patients undergoing sacrectomy: two case reports. | BACKGROUND: Sacral neoplasms often present as large masses that often require sacrectomy. Multiple sacral nerve roots may be compromised post-sacrectomy and postoperative complications may result in impaired mobility, pain, orthostasis, and neurogenic bowel and bladder.CASE SERIES: Case 1, 58 year-old female with a sac... | ['Aged', 'Chordoma', 'Female', 'Fibroma', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Sacrum', 'Spinal Neoplasms'] | 29,898,586 | [['M01.060.116.100'], ['C04.557.465.220'], ['C04.557.450.565.590.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['A02.835.232.834.717'], ['C04.588.149.828', 'C05.116.231.828', 'C05.116.900.801']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A suppressor analysis of residues involved in cation transport in the lactose permease: identification of a coupling sensor. | Four amino acids critical for lactose permease function were altered using site-directed mutagenesis. The resulting Quad mutant (E269Q/R302L/H322Q/E325Q) was expressed at 60% of wild-type levels but found to have negligible transport activity. The Quad mutant was used as a parental strain to isolate suppressors that re... | ['Amino Acid Substitution', 'Biological Transport', 'Blotting, Western', 'Cations', 'Escherichia coli', 'Kinetics', 'Lactose', 'Melibiose', 'Membrane Transport Proteins', 'Monosaccharide Transport Proteins', 'Mutagenesis, Site-Directed', 'Mutation', 'Plasmids', 'Thiogalactosides'] | 16,988,863 | [['E05.393.420.601.035', 'G05.558.109'], ['G03.143'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D01.248.497.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661', 'G02.111.490'], ['D09.698.629.305.340', 'D09.947.750.340'], ['D09.698.62... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study. | BACKGROUND: Preoperative radiotherapy has been shown to decrease the local recurrence rate of patients with locally advanced rectal cancer. Capecitabine and oxaliplatin are both active anticancer agents in the treatment of patients with advanced colorectal cancer and have radiosensitizing properties. Therefore, these d... | ['Adenocarcinoma', 'Administration, Oral', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Capecitabine', 'Combined Modality Therapy', 'Deoxycytidine', 'Female', 'Fluorouracil', 'Humans', 'Injections, Intravenous', 'Liver Neoplasms', 'Male', 'Maximum Tolerated Dose', 'Middle Age... | 16,219,623 | [['C04.557.470.200.025'], ['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['E02.186'], ['D03.383.742.680.245.50... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Secondary anionic phospholipid binding site and gating mechanism in Kir2.1 inward rectifier channels. | Inwardly rectifying potassium (Kir) channels regulate multiple tissues. All Kir channels require interaction of phosphatidyl-4,5-bisphosphate (PIP2) at a crystallographically identified binding site, but an additional nonspecific secondary anionic phospholipid (PL(-)) is required to generate high PIP2 sensitivity of Ki... | ['Anions', 'Humans', 'Molecular Docking Simulation', 'Phospholipids', 'Potassium Channels, Inwardly Rectifying'] | 24,270,915 | [['D01.248.497.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595.249', 'L01.224.160.249'], ['D10.570.755'], ['D12.776.157.530.400.600.450', 'D12.776.543.550.450.750.450', 'D12.776.543.585.400.750.450']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Childhood exposure to sexual abuse and partnership outcomes at age 30. | BACKGROUND: In this study, 30-year longitudinal data from the Christchurch Health and Development Study (CHDS) were used to examine the associations between childhood exposure to sexual abuse and intimate relationship outcomes at age 30. In addition, a broad range of early childhood and family confounding factors were ... | ['Adolescent', 'Adult', 'Child', 'Child Abuse, Sexual', 'Family Characteristics', 'Female', 'Follow-Up Studies', 'Humans', 'Interpersonal Relations', 'Male', 'Risk Factors', 'Young Adult'] | 19,653,922 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.5... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Immune system activation by CDDP and "poly-plat". | Murine peritoneal macrophages, human fibroblasts and human ovarian teratocarcinoma cells were treated with CDDP (10 micrograms/ml) and "poly-plat" (10 micrograms/ml) for 2 h and cultured for 2-96 h. After "poly-plat" treatment macrophages developed cytoplasmic extensions much faster and secreted higher levels of interl... | ['Adjuvants, Immunologic', 'Animals', 'Antineoplastic Agents', 'Cisplatin', 'Female', 'Fibroblasts', 'Humans', 'Interleukin-2', 'Macrophage Activation', 'Macrophages, Peritoneal', 'Mice', 'Organoplatinum Compounds', 'Ovarian Neoplasms', 'Teratocarcinoma'] | 10,953,351 | [['D27.505.696.477.067'], ['B01.050'], ['D27.505.954.248'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374.48... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stereometry of the red pulp on the human spleen. II) The normal spleen. | The stereometric measurements obtained in three human normal spleens surgically removed for trauma have been submitted to statistical evaluation. On the basis of the original counts, some stereometric measures of the normal splenic red pulp have been determined, namely per cent volume of sinuses, per cent volume of cor... | ['Adult', 'Biometry', 'Female', 'Humans', 'Male', 'Mathematics', 'Spleen', 'Splenectomy', 'Splenic Rupture'] | 17,955,636 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative study of the influence of pregnancy and hormonal treatment on mammary carcinogenesis. | Since it has been shown that pregnancy protects the mammary gland from chemically induced carcinogenesis, this study was designed with the dual purpose of determining whether treatment of young virgin rats with the placental hormone chorionic gonadotropin (hCG) mimics pregnancy-induced changes in the tumourigenic respo... | ['9,10-Dimethyl-1,2-benzanthracene', 'Adenocarcinoma', 'Animals', 'Anticarcinogenic Agents', 'Chorionic Gonadotropin', 'Female', 'Mammary Neoplasms, Experimental', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Rats', 'Rats, Inbred Strains'] | 1,911,188 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['C04.557.470.200.025'], ['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['G08.686.784... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Self-reported eating rate aligns with laboratory measured eating rate but not with free-living meals. | Methodological differences may be responsible for variable results from eating rate (ER) studies. It is unknown whether self-reported, lab-measured, and free-living ER's align. This study was the first to explore relationships among self-reported, laboratory-measured and free-living ER's. We investigated this relations... | ['Adolescent', 'Diet Surveys', 'Eating', 'Feeding Behavior', 'Female', 'Humans', 'Male', 'Meals', 'Reproducibility of Results', 'Self Report', 'Young Adult'] | 23,266,516 | [['M01.060.057'], ['E05.318.308.980.485.350', 'N05.715.360.300.800.469.300', 'N06.850.505.616.300', 'N06.850.520.308.980.469.350'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300.590', 'J02.500.590'], ['E05.318.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Two distinct activities contribute to the oncogenic potential of the adenovirus type 5 E4orf6 protein. | Previous studies have shown that the adenovirus type 5 (Ad5) E4orf6 gene product displays features of a viral oncoprotein. It initiates focal transformation of primary rat cells in cooperation with Ad5 E1 genes and confers multiple additional transformed properties on E1-expressing cells, including profound morphologic... | ['Adenovirus E1A Proteins', 'Adenovirus E1B Proteins', 'Adenovirus E4 Proteins', 'Amino Acid Sequence', 'Animals', 'Binding Sites', 'Carcinogenicity Tests', 'Cell Transformation, Viral', 'Humans', 'Mice', 'Mice, Nude', 'Molecular Sequence Data', 'Mutagenesis', 'Oncogene Proteins', 'Rats', 'Rats, Sprague-Dawley', 'Subce... | 10,799,592 | [['D12.776.460.050.100', 'D12.776.624.664.520.045.050.100', 'D12.776.930.100', 'D12.776.964.700.045.050.100', 'D23.050.285.062.045', 'D23.050.327.062.045'], ['D12.776.460.050.110', 'D12.776.624.664.520.045.050.110', 'D12.776.930.110', 'D12.776.964.700.045.050.110', 'D23.050.285.062.050', 'D23.050.327.062.050'], ['D12.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Efficacy of oral administration and oral intake of edible vaccines. | To evaluate whether vaccine administration via intragastric gavage is indicative for the outcome of edible vaccines, mice were orally immunised with ovalbumin (OVA) mixed with or without Vibrio cholerae toxin (CT) in various compositions via various routes: (1) OVA dissolved in saline and intragastrically (IG) administ... | ['Administration, Oral', 'Animals', 'Antibodies, Bacterial', 'Antibody-Producing Cells', 'Drinking', 'Enterotoxins', 'Female', 'Food', 'Immunoglobulin A', 'Immunoglobulin G', 'Mice', 'Ovalbumin', 'Vaccines, Edible'] | 12,413,735 | [['E02.319.267.100'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['A11.063', 'A15.382.032'], ['G07.203.650.283.249', 'G10.261.330.249'], ['D23.946.330'], ['G07.203.300', 'J02.500'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Can word formation be understood or understanded by semantics alone? | Arguments concerning the relative role of semantic and grammatical factors in word formation have proven to be a wedge issue in current debates over the nature of linguistic representation and processing. In the present paper, we re-examine claims by Ramscar [Ramscar, M. (2002). The role of meaning in inflection: Why t... | ['Cognition', 'Humans', 'Psycholinguistics', 'Semantics', 'Vocabulary'] | 17,498,681 | [['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.694', 'F04.096.586', 'L01.559.598.628'], ['L01.559.598.745'], ['L01.559.598.901']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Practice patterns and role perception of advanced practice nurses: A nationwide cross-sectional study. | AIMS: To provide an overview of the practice patterns of advanced practice nurses and to explore their perceptions of their role in Singapore.BACKGROUND: Role expansion of advanced practice nurses is increasingly popular in healthcare systems. However, their practice patterns remain variable, thereby introducing role a... | ['Adult', 'Advanced Practice Nursing', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', "Nurse's Role", "Practice Patterns, Nurses'", 'Singapore', 'Surveys and Questionnaires'] | 30,776,163 | [['M01.060.116'], ['H02.478.676.074'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['N04.590.374.553', 'N05.300.581'], ['Z01.252.145.774'], ['E05.318.308.980', 'N05.71... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
The Evaluation of Benefit of Newly Prepared Reversible Inhibitors of Acetylcholinesterase and Commonly Used Pyridostigmine as Pharmacological Pretreatment of Soman-Poisoned Mice. | AIM: The ability of four newly prepared reversible inhibitors of acetylcholinesterase (6-chlorotacrine, 7-phenoxytacrine, compounds 1 and 2) and currently used carbamate pyridostigmine to increase the resistance of mice against soman and the efficacy of antidotal treatment of soman-poisoned mice was evaluated.METHODS: ... | ['Animals', 'Cholinesterase Inhibitors', 'Drug Therapy, Combination', 'Humans', 'Isoquinolines', 'Male', 'Mice', 'Pyridinium Compounds', 'Pyridostigmine Bromide', 'Soman'] | 28,418,831 | [['B01.050'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.531'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.383.725.762'], ['D03.383.725.762.740'], ['D02.705.429.750.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Learning from our older people: pilot study findings on responding to heat. | AIMS: With the advent of climate change, it is important that strategies be put in place to minimise the effects of heat. These impacts can be compounded by other factors such as location and age. This exploratory pilot study focuses on older people in a rural Victorian community that regularly experiences hot weather.... | ['Activities of Daily Living', 'Adaptation, Psychological', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Climate', 'Extreme Heat', 'Female', 'Focus Groups', 'Heat Stress Disorders', 'Housing for the Elderly', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Pilot Projects', 'Protective Factors', 'Resid... | 24,521,491 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.058'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.750.775.271', 'N06.230.300.100.725.232.500', 'N06.230.300.100.725.710.380.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'I... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Autonomic contribution to blood pressure and metabolism in obesity. | Obesity is associated with alterations in the autonomic nervous system that may contribute to the increase in blood pressure and resting energy expenditure present in this condition. To test this hypothesis, we induced autonomic withdrawal with the ganglionic blocker trimethaphan in 10 lean (32+/-3 years) and 10 obese ... | ['Adult', 'Autonomic Nervous System', 'Blood Pressure', 'Cardiovascular System', 'Energy Metabolism', 'Female', 'Ganglionic Blockers', 'Humans', 'Hypertension', 'Male', 'Obesity', 'Rest', 'Systole', 'Thinness', 'Trimethaphan', 'Vascular Resistance'] | 17,116,758 | [['M01.060.116'], ['A08.800.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07'], ['G03.295'], ['D27.505.696.663.050.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['I03.450.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Role of rho-kinase activity in angiotensin II-induced contraction of rabbit clitoral cavernosum smooth muscle. | Isometric tension measurement using a selective Rho-kinase inhibitor (+)- (R)-trans4-(1-aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide (Y-27632) and a selective myosin light chain kinase (MLCK) inhibitor 1-(5-iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML7) were used in rabbit clitoral cavern... | ['Amides', 'Angiotensin II', 'Animals', 'Azepines', 'Clitoris', 'Enzyme Inhibitors', 'Female', 'In Vitro Techniques', 'Intracellular Signaling Peptides and Proteins', 'Isometric Contraction', 'Muscle, Smooth', 'Myosin-Light-Chain Kinase', 'Naphthalenes', 'Nitric Oxide', 'Phenylephrine', 'Protein-Serine-Threonine Kinase... | 12,494,280 | [['D02.065'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['D03.383.066'], ['A05.360.319.887.436'], ['D27.505.519.389'], ['E05.481'], ['D12.644.360', 'D12.776.476'], ['G11.427.494.472'], ['A02.633.570', 'A10... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stable isotope labeling and 2,3,5,4'-tetrahydroxystilbene-2-O-â-D-glucopyranoside biosynthetic pathway characterization in Fallopia multiflora. | MAIN CONCLUSION: The THSG biosynthetic pathway in F. multiflora was characterized, and enzymatic activities responsible for the resveratrol synthesis, hydroxylation, and glycosylation reactions involved in THSG biosynthesis were confirmed in vitro. The biosynthetic origin of 2,3,5,4'-tetrahydroxystilbene-2-O-â-D-glucop... | ['Fallopia multiflora', 'Glucosides', 'Glycosylation', 'Hydroxylation', 'Isotope Labeling', 'Metabolic Networks and Pathways', 'Resveratrol', 'Stilbenes'] | 29,138,972 | [['B01.650.940.800.575.912.250.825.359.590'], ['D09.408.348'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['G02.111.385', 'G02.607.348', 'G03.425'], ['E05.522'], ['G03.493'], ['D02.455.426.559.389.150.700.725.875', 'D02.455.426.559.389.657.715.500'], ['D02.455.426.559.389.150.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interaction between hsp70 and hsp40, eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53. | We have recently identified a novel 40-kDa heatshock protein hsp40 as a mammalian homologue of bacterial DnaJ protein. Here we demonstrate the physical interaction between hsp70 (DnaK homologue) and hsp40 in human cells as determined by immunoprecipitation methods. Co-immunoprecipitation of hsp70 with hsp40 was depende... | ['Escherichia coli Proteins', 'Genes, p53', 'HSP40 Heat-Shock Proteins', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Humans', 'Mutation', 'Precipitin Tests', 'Tumor Cells, Cultured'] | 7,828,728 | [['D12.776.097.275'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['D12.776.580.216.292'], ['D12.776.580.216.375'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['E01.370.225.812.735.645', 'E05.196.150.639.500', 'E05.200.812.735.645', 'E05.478.594.76... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Social Behavior and Impairments in Social Cognition Following Traumatic Brain Injury. | OBJECTIVES: The negative effect of changes in social behavior following traumatic brain injury (TBI) are known, but much less is known about the neuropsychological impairments that may underlie and predict these changes. The current study investigated possible associations between post-injury behavior and neuropsycholo... | ['Aged', 'Brain Injuries, Traumatic', 'Case-Control Studies', 'Cognition Disorders', 'Emotions', 'Female', 'Humans', 'Intention', 'Judgment', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Reaction Time', 'Semantics', 'Social Behavior', 'Verbal Behavior'] | 28,399,953 | [['M01.060.116.100'], ['C10.228.140.199.444', 'C10.900.300.087.235', 'C26.915.300.200.194'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F03.615.250'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['F02.463.785.626'], ['M01.060.116.63... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Subclinical hypothyroidism in obese patients: relation to resting energy expenditure, serum leptin, body composition, and lipid profile. | OBJECTIVE: To evaluate whether subclinical hypothyroidism (SH) affects resting energy expenditure (REE) as well as body composition, lipid profile, and serum leptin in obese patients.RESEARCH METHODS AND PROCEDURES: A total of 108 obese patients with SH defined as normal free thyroxine levels and thyroid-stimulating ho... | ['Basal Metabolism', 'Body Composition', 'Calorimetry, Indirect', 'Case-Control Studies', 'Electric Impedance', 'Female', 'Humans', 'Hypothyroidism', 'Leptin', 'Lipids', 'Male', 'Mental Recall', 'Middle Aged', 'Obesity', 'Radioimmunoassay', 'Thyrotropin'] | 11,323,445 | [['G03.295.154'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E05.196.131.655'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G01.358.500.249.277.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Administration of donor splenocytes via the respiratory tract generates CD8á+ | BACKGROUND: We previously showed that pretreatment with intratracheal delivery (ITD) of alloantigen induced prolonged cardiac allograft survival and generated regulatory T cells (Tregs) in mice. In this study, we examined the role of splenic dendritic cells (DCs) in the ITD model.METHODS: CBA mice were treated with ITD... | ['Adoptive Transfer', 'Animals', 'CD8 Antigens', 'Cells, Cultured', 'Dendritic Cells', 'Heart Transplantation', 'Histocompatibility Antigens', 'Interleukin-10', 'Isoantigens', 'Lymphocyte Activation', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Respiratory System', 'Spleen', 'T-Lymphocytes, Regulatory', ... | 29,990,543 | [['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['D23.050.301.264.894.108', 'D23.101.100.894.108'], ['A11.251'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['D23.050.301.500', 'D23.050.705.552'], ['D12.644.276.37... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regional deposition of gases and particles in the lung: implications for mixtures. | Considerations of the health effects of pollutant mixtures usually focus on the interactions of biochemically-induced events. For example, the effect of metabolic enzyme induction by one pollutant on the subsequent effect of another pollutant is often considered. Another important aspect of mixture interactions is the ... | ['Administration, Inhalation', 'Air Pollutants', 'Dose-Response Relationship, Drug', 'Humans', 'Lung', 'Ozone', 'Particle Size'] | 8,571,369 | [['E02.319.267.050'], ['D27.888.284.101'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['D01.362.670.600'], ['G02.712']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of illuminance on the directions of chromostereopsis and transverse chromatic aberration observed with natural pupils. | The direction of chromostereopsis observed with a natural pupil and the direction of the monocularly perceived disparity between coloured targets (F and C lines - 486 and 656 nm) have been measured in a sample of 30 subjects at 10 and 1000 lx. At both illumination levels approximately equal numbers of subjects perceive... | ['Adult', 'Color Perception', 'Depth Perception', 'Female', 'Humans', 'Light', 'Male', 'Middle Aged', 'Pupil', 'Spectrophotometry', 'Visual Fields'] | 2,216,476 | [['M01.060.116'], ['F02.463.593.932.217'], ['F02.463.593.200', 'F02.463.593.778.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['M01.060.116.630'], ['A09.371.060.450.780', 'A09.371.894.513.780'], ['E05.196.712.726', 'E05.196.867.826'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rhipicephalus sanguineus importation into the UK: surveillance, risk, public health awareness and One Health response. | As part of Public Health England's assessment of vectorborne disease risk to public health in the UK, tick specimens are regularly submitted by veterinarians for identification via the Tick Surveillance Scheme. Recently, a number of these specimens have been identified as the brown dog tick, Rhipicephalus sanguineus Th... | ['Animals', 'Dog Diseases', 'Dogs', 'Global Health', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Population Surveillance', 'Public Health', 'Rhipicephalus sanguineus', 'Risk', 'Tick Infestations', 'Tick-Borne Diseases', 'Travel', 'United Kingdom'] | 27,999,153 | [['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['H02.403.371', 'N01.400.337'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N06.850.780.675'], ['H02.403.720', '... | ['Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
The addition of epinephrine enhances postoperative analgesia by intrathecal morphine. | To investigate whether the addition of epinephrine would enhance postoperative pain relief by intrathecal morphine, we studied 36 patients scheduled to have spinal anesthesia for gynecologic surgery. Patients were randomly allocated to one of three groups: the first received epinephrine 0.12 mg, morphine 0.2 mg, and hy... | ['Adult', 'Aged', 'Analgesia', 'Drug Synergism', 'Drug Therapy, Combination', 'Epinephrine', 'Female', 'Humans', 'Hysterectomy', 'Injections, Spinal', 'Middle Aged', 'Morphine', 'Motor Activity', 'Nausea', 'Ovariectomy', 'Pain, Postoperative', 'Postoperative Care'] | 7,653,813 | [['M01.060.116'], ['M01.060.116.100'], ['E03.091'], ['G07.690.773.968.477'], ['E02.319.310'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E02.319.267.530.580'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Measurement of serum PA values by a newly developed enzyme immunoassay]. | Serum prostate-specific antigen (PA) values detected by a newly developed enzyme immunoassay (EIA, MARKIT-M PA) as a successor of MARKIT-F PA, which has been a leading kit in Japan, were evaluated for its role in the diagnosis of cancer of the prostate and follow-up of the patients afflicted with the disease. The syste... | ['Humans', 'Immunoenzyme Techniques', 'Male', 'Prostate-Specific Antigen', 'Prostatic Hyperplasia', 'Prostatic Neoplasms', 'Reagent Kits, Diagnostic', 'Reference Values'] | 7,681,886 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866.249.500', 'D23.050.285.625', 'D23.101.140.625'], ['C12.294.565.500'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A genome scan for Plasmodium falciparum malaria identifies quantitative trait loci on chromosomes 5q31, 6p21.3, 17p12, and 19p13. | BACKGROUND: Genome-wide studies have mapped several loci controlling Plasmodium falciparum mild malaria and parasitaemia, only two of them being significant at the genome level. The objective of the present study was to identify malaria resistance loci in individuals living in Burkina Faso.METHODS: A genome scan that i... | ['Adolescent', 'Adult', 'Burkina Faso', 'Child', 'Child, Preschool', 'Chromosomes, Human', 'Disease Resistance', 'Genome-Wide Association Study', 'Humans', 'Infant', 'Malaria, Falciparum', 'Male', 'Quantitative Trait Loci', 'Young Adult'] | 24,884,991 | [['M01.060.057'], ['M01.060.116'], ['Z01.058.290.190.245'], ['M01.060.406'], ['M01.060.406.448'], ['A11.284.187.520.300', 'G05.360.162.520.300'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[A case of severe systemic juvenile idiopathic arthritis introduced tocilizumab in early phase of the disease]. | A 14-year-old boy was admitted in the former hospital with remittent fever, erythematous rash, joint pain, and muscle pain. Antibiotics were ineffectively administered and then, methylprednisolone (mPSL) pulse therapy with methotrexate was introduced under the diagnosis of suspected systemic juvenile idiopathic arthrit... | ['Adolescent', 'Antibodies, Monoclonal, Humanized', 'Arthritis, Juvenile', 'Biopsy', 'Early Intervention, Educational', 'Humans', 'Interleukin-6', 'Male', 'Multimodal Imaging', 'Positron-Emission Tomography', 'Tomography, X-Ray Computed'] | 24,974,931 | [['M01.060.057'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Is there a difference in pregnancy and glycemic outcome in patients with type 1 diabetes on insulin pump with constant or intermittent glucose monitoring? A pilot study. | BACKGROUND: The aim of the study is to describe glycemic and insulin outcomes by trimester and maternal and fetal outcome in patients with type 1 diabetes using an insulin pump with constant or intermittent continuous glucose monitoring (CGM).METHODS: Twenty-five women with type 1 diabetes with newly diagnosed pregnanc... | ['Adult', 'Blood Glucose Self-Monitoring', 'Cesarean Section', 'Diabetes Mellitus, Type 1', 'Diabetic Ketoacidosis', 'Female', 'Fetal Macrosomia', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemia', 'Hypoglycemic Agents', 'Insulin', 'Insulin Infusion Systems', 'Monitoring, Ambulatory', 'Pilot Projects', 'Pregnancy', 'Pr... | 21,751,889 | [['M01.060.116'], ['E01.370.225.124.100.105', 'E01.370.374.100', 'E01.370.520.100', 'E02.900.950.500', 'E05.200.124.100.105'], ['E04.520.252.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['C13.703.170.500', 'C13.703.277.570', 'C13.70... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source. | Silicon photonic chips have the potential to realize complex integrated quantum information processing circuits, including photon sources, qubit manipulation, and integrated single-photon detectors. Here, we present the key aspects of preparing and testing a silicon photonic quantum chip with an integrated photon sourc... | ['Equipment Design', 'Equipment Failure Analysis', 'Interferometry', 'Photons', 'Quantum Theory', 'Silicon'] | 28,447,975 | [['E05.320'], ['E05.325.192'], ['E05.490'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['H01.671.579.800'], ['D01.268.513.937']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Profile of gender violence by intimate partners]. | OBJECTIVE: To investigate the prevalence and profile of gender violence (physical, psychological, and sexual) perpetrated against women by current or former intimate partners.METHODS: This is a cross-sectional study carried out at a primary healthcare unit in the city of Porto Alegre, Southern Brazil. Our sample compri... | ['Adolescent', 'Adult', 'Brazil', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Sex Offenses', 'Socioeconomic Factors', 'Spouse Abuse', 'Surveys and Questionnaires'] | 16,254,643 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], [... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Power of an effective clinical conversation: improving accrual onto clinical trials. | The National Cancer Institute (NCI) is actively transforming clinical trials to revitalize the clinical trials system and improve patient accrual. For more than 30 years, NCI has provided information and communication resources about cancer clinical trials. The Institute supports a clinical trials Web site (www.cancer.... | ['Age Factors', 'Aged', 'Clinical Trials as Topic', 'Communication', 'Community-Based Participatory Research', 'Female', 'Humans', 'Male', 'National Cancer Institute (U.S.)', 'Neoplasms', 'Patient Selection', 'Randomized Controlled Trials as Topic', 'Sex Factors', 'United States'] | 23,277,764 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F01.145.209', 'L01.143'], ['H01.770.644.193', 'N05.425.104'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.409.418.750.600.650.496.150', 'N03.540.052.750.150', 'N03.54... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Geographicals [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Inhaled nitric oxide in acute respiratory distress syndrome: a pilot randomized controlled study. | This pilot randomized controlled clinical trial of patients with ARDS was implemented to study the impact of inhaled nitric oxide (inhNO) on lung function, morbidity, and mortality. Thirty patients with ARDS were randomly allocated to usual care or usual care plus inhNO. The optimal dose of inhNO was determined to be b... | ['Administration, Inhalation', 'Adolescent', 'Adult', 'Aged', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Nitric Oxide', 'Pilot Projects', 'Respiration, Artificial', 'Respiratory Distress Syndrome', 'Respiratory Mechanics'] | 9,603,127 | [['E02.319.267.050'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Selective late steroid withdrawal after renal transplantation. | Steroid withdrawal (SW) after paediatric renal transplantation (RTPL) is controversial. Selective late SW has been performed in our unit since 1995. The safety and effects of SW were analysed retrospectively in 47 patients undergoing RTPL between 1995 and 2004. Initial immunosuppression consisted of cyclosporine A, aza... | ['Adolescent', 'Adolescent Development', 'Azathioprine', 'Blood Pressure', 'Child', 'Child Development', 'Child, Preschool', 'Cyclosporine', 'Drug Therapy, Combination', 'Female', 'Graft Rejection', 'Graft Survival', 'Humans', 'Immunosuppressive Agents', 'Kidney', 'Kidney Transplantation', 'Male', 'Mycophenolic Acid', ... | 17,874,140 | [['M01.060.057'], ['F01.525.049', 'G07.345.374.500'], ['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['E01.370.600.875.249', 'G09.330.380.076'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['E02.319.310'], ['G12.875.545.32... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Robotic-assisted laparoscopic ureteral reimplantation with psoas hitch: a multi-institutional, multinational evaluation. | OBJECTIVES: To report the collective experience of three multinational institutions with the use of robotics to evaluate and treat complex distal ureteral obstruction.METHODS: A total of 12 patients from The Ohio State University, Columbus, Ohio; Onze-Lieve-Vrouw Ziekenhuis, Aalst, Belgium; and Hospital Sultanah Aminah... | ['Adult', 'Aged', 'Anastomosis, Surgical', 'Female', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Psoas Muscles', 'Robotics', 'Ureter', 'Ureteral Diseases', 'Ureteral Obstruction', 'Urinary Bladder', 'Urinary Fistula', 'Urologic Surgical Procedures', 'Vaginal Fistula'] | 18,384,858 | [['M01.060.116'], ['M01.060.116.100'], ['E04.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['A02.633.567.825'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['A05.810.776'], ['C12.777.725', 'C13.351.968.725'], ['C12.777.725.776... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
Inulin alters the intestinal microbiota and short-chain fatty acid concentrations in growing pigs regardless of their basal diet. | Inulin stimulates intestinal bifidobacteria in humans and rodents but its effect in pigs is inconsistent. We assessed the effect of inulin on the intestinal microbiota by fluorescent in situ hybridization in growing pigs (age 9-12 wk). Pigs (n = 64) were assigned to 2 types of basal diets [wheat and barley (WB) or corn... | ['Acetates', 'Aging', 'Animal Feed', 'Animals', 'Bacteria', 'Bifidobacterium', 'Butyrates', 'Diet', 'Intestines', 'Inulin', 'Propionates', 'Swine'] | 16,614,404 | [['D02.241.081.018', 'D10.251.400.045'], ['G07.345.124'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B03'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['D02.241.081.114', 'D10.251.400.143'], ['G07.203.650.240'], ['A03.556.124'], ['D05.750.078.562.855.750', 'D09.301.915.750', 'D09.698.350.500', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Glomerular atrial natriuretic factor receptors in spontaneously hypertensive rats. | There are differences in the renal handling of sodium between spontaneously hypertensive rats (SHR) and their normotensive controls. We investigated whether this difference may be associated with changes in plasma and tissue atrial natriuretic factor (ANF) levels and with alterations in glomerular ANF receptors at 4, 8... | ['Animals', 'Atrial Natriuretic Factor', 'Blood Pressure', 'Body Weight', 'Cyclic GMP', 'Heart Atria', 'Hematocrit', 'Kidney Glomerulus', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Receptors, Atrial Natriuretic Factor', 'Receptors, Cell Surface', 'Time Factors'] | 2,544,518 | [['B01.050'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and secretion of human chorionic gonadotropin subunits by cultured human malignant cells. | The synthesis and secretion of human chorionic gonadotropin (hCG) subunits have been studied by pulse-chase techniques in JAR choriocarcinoma cells, which produce both the alpha and beta subunits of hCG "eutopically," that is, as part of their expected repertoire of gene products, and in three cell lines that produce e... | ['Carcinoma, Bronchogenic', 'Cell Line', 'Choriocarcinoma', 'Chorionic Gonadotropin', 'Female', 'HeLa Cells', 'Humans', 'Lung Neoplasms', 'Macromolecular Substances', 'Molecular Weight', 'Pregnancy', 'Protein Biosynthesis'] | 7,188,695 | [['C04.588.894.797.520.109.220', 'C08.381.540.140', 'C08.785.520.100.220'], ['A11.251.210'], ['C04.557.465.955.207', 'C04.557.470.200.025.455', 'C04.850.908.208', 'C13.703.720.949.208'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['A11.251.210.190.400', 'A11.251.860.180.40... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thyroid hormones and male sexual function. | The role of thyroid hormones in the control of erectile functioning has been only superficially investigated. The aim of the present study was to investigate the association between thyroid and erectile function in two different cohorts of subjects. The first one derives from the European Male Ageing Study (EMAS study)... | ['Adult', 'Aged', 'Case-Control Studies', 'Cohort Studies', 'Cross-Sectional Studies', 'Erectile Dysfunction', 'Humans', 'Hyperthyroidism', 'Hypothyroidism', 'Male', 'Middle Aged', 'Retrospective Studies', 'Smoking', 'Thyrotropin', 'Thyroxine'] | 22,834,774 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C12.294.644.486', 'F03.835.400'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Is there vitamin D deficiency in children in a sunny Mediterranean city?]. | INTRODUCTION: Despite the increasing interest in vitamin D functions, new cases of deficiency have been reported in sunny regions where optimal levels are expected. The aim of this study was to analyze 25-hydroxivitamin D levels in children younger than 2 years admitted for acute mild diseases in a tertiary hospital in... | ['Climate', 'Cross-Sectional Studies', 'Humans', 'Infant', 'Prospective Studies', 'Spain', 'Sunlight', 'Vitamin D', 'Vitamin D Deficiency'] | 26,058,340 | [['G16.500.275.071', 'N06.230.300.100.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['Z01.542.846'], ['G01.358.500.505.650.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Glucocorticosteroids and â₂-adrenoceptor agonists synergize to inhibit airway smooth muscle remodeling. | Airway remodeling, including increased airway smooth muscle (ASM) mass and contractility, contributes to increased airway narrowing in asthma. Increased ASM mass may be caused by exposure to mitogens, including platelet-derived growth factor (PDGF) and collagen type I, which induce a proliferative, hypocontractile ASM ... | ['Adrenergic beta-2 Receptor Agonists', 'Airway Remodeling', 'Androstadienes', 'Animals', 'Budesonide', 'Cattle', 'Cell Cycle', 'Cell Proliferation', 'Collagen Type I', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclin-Dependent Kinase Inhibitor p57', 'Dexamethasone', 'Drug Synergism', 'Fenoterol', 'Fluticasone', 'Gluco... | 22,685,341 | [['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['C23.300.017', 'G09.772.029'], ['D04.210.500.054.079.129'], ['B01.050'], ['D04.210.500.745.745.654.105'], ['B01.050.150.900.649.313.500.380.271'], ['G04.144'], ['G04.161.750', 'G07.345.249.410.750'], ['D05.750.078.280.300.100', 'D12.776.860.300.2... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Expression of transcription factor SOX4 and its clinical significance in female lung cancer patients in Xuanwei area, Yunnan Province]. | OBJECTIVE: To investigate the expression of transcription factor SOX4 in lung cancer tissues of female patients in Xuanwei area, Yunnan Province, and explore its correlation with clinicopathological characteristics and prognosis of the female patients.METHODS: Real-time PCR was applied on lung cancer specimens and thei... | ['Adenocarcinoma', 'Adult', 'Aged', 'Carcinoma, Squamous Cell', 'China', 'Female', 'Follow-Up Studies', 'Humans', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Staging', 'Proportional Hazards Models', 'RNA, Messenger', 'SOXC Transcription Factors', 'Survival Rate', 'Up-Regulation'] | 23,880,001 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['Z01.252.474.164'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785... | ['Diseases [C]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
DEAH box RNA helicase DHX38 associates with satellite I noncoding RNA involved in chromosome segregation. | Noncoding (nc) RNA called satellite I is transcribed from the human centromere region. Depletion of this ncRNA results in abnormal nuclear morphology because of defects in chromosome segregation. Some protein factors interact with this ncRNA and function as a component of a nc ribonucleoprotein (RNP) complex in mitotic... | ['Cell Line', 'Centromere', 'Chromosome Segregation', 'DEAD-box RNA Helicases', 'DNA, Satellite', 'Gene Knockdown Techniques', 'Humans', 'RNA Splicing Factors', 'RNA, Untranslated'] | 31,166,646 | [['A11.251.210'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['G04.144.220.220.625', 'G05.113.220.625'], ['D08.811.913.696.445.735.720.249'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['E05.393.335.500'], ['B01.0... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Study of precorneal tear film thickness and structure by interferometry and confocal microscopy. | Past measurements of precorneal tear film thickness in rabbits and humans gave values of 4-7 microns. These have been the accepted values. However, measurements presented in this report are much higher. Earlier techniques may have changed film thickness or not have fully included the layer containing mucus. Little is k... | ['Animals', 'Cornea', 'Image Processing, Computer-Assisted', 'Interferometry', 'Light', 'Microscopy', 'Mucus', 'Tears'] | 1,582,804 | [['B01.050'], ['A09.371.060.217'], ['L01.224.308'], ['E05.490'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['A12.200.503'], ['A12.200.882']] | ['Organisms [B]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Rectally administered misoprostol versus intravenous oxytocin infusion during cesarean delivery to reduce intraoperative and postoperative blood loss. | OBJECTIVE: To compare the efficacy of rectally administered misoprostol with intravenous oxytocin infusion in preventing uterine atony and blood loss during cesarean delivery.METHODS: In this prospective, randomized, double-blind trial, 200 women undergoing cesarean delivery who did not have risk factors for postpartum... | ['Administration, Rectal', 'Adult', 'Blood Loss, Surgical', 'Cesarean Section', 'Double-Blind Method', 'Female', 'Humans', 'Infusions, Intravenous', 'Misoprostol', 'Oxytocics', 'Oxytocin', 'Postoperative Complications', 'Pregnancy', 'Prospective Studies', 'Uterine Inertia', 'Young Adult'] | 20,070,961 | [['E02.319.267.120.655.750'], ['M01.060.116'], ['C23.550.414.300', 'C23.550.505.300'], ['E04.520.252.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['D10.251.355.255.550.775.450... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Properties and expression of a multidrug efflux pump AcrAB-KocC from Klebsiella pneumoniae. | We previously reported that we had cloned genes responsible for multidrug resistance from the chromosomal DNA of Klebsiella pneumoniae MGH78578 using a drug-hypersusceptible Escherichia coli strain as a host. One of the recombinant plasmids pETV6 conferred resistance to host cells against a wide range of antimicrobial ... | ['Carrier Proteins', 'Chromosomes, Bacterial', 'Cloning, Molecular', 'DNA, Bacterial', 'Drug Resistance, Multiple, Bacterial', 'Escherichia coli', 'Ethidium', 'Fluorescent Dyes', 'Genes, Bacterial', 'Klebsiella pneumoniae', 'Microbial Sensitivity Tests', 'Plasmids', 'RNA, Bacterial', 'Reverse Transcriptase Polymerase C... | 18,379,044 | [['D12.776.157'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['E05.393.220'], ['D13.444.308.212'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D03.633.300.633.416'], ['D27.720.233.348', 'D27.720.470.4... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antral hypertrophic gastritis: a rare cause of iron deficiency. | A case of an unusual hypertrophic gastropathy confined to the gastric antrum which presented with chronic anaemia is described. The clinical and pathological features are contrasted with Menetrier's disease and hypersecretory hypertrophic gastropathy, and a possible relation to solitary hyperplastic (regenerative) poly... | ['Aged', 'Anemia, Hypochromic', 'Capillaries', 'Female', 'Gastritis', 'Gastritis, Hypertrophic', 'Humans', 'Pyloric Antrum', 'Thrombosis'] | 3,988,952 | [['M01.060.116.100'], ['C15.378.071.196'], ['A07.015.461.165'], ['C06.405.205.697', 'C06.405.748.398'], ['C06.405.205.697.410', 'C06.405.748.398.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.875.875.716'], ['C14.907.355.830']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Determination of the melon chloroplast and mitochondrial genome sequences reveals that the largest reported mitochondrial genome in plants contains a significant amount of DNA having a nuclear origin. | BACKGROUND: The melon belongs to the Cucurbitaceae family, whose economic importance among vegetable crops is second only to Solanaceae. The melon has a small genome size (454 Mb), which makes it suitable for molecular and genetic studies. Despite similar nuclear and chloroplast genome sizes, cucurbits show great varia... | ['Cell Nucleus', 'Chromosome Mapping', 'Cucurbitaceae', 'DNA, Plant', 'Genetic Variation', 'Genome Size', 'Genome, Chloroplast', 'Genome, Mitochondrial', 'Genome, Plant', 'Microsatellite Repeats', 'Molecular Sequence Annotation', 'Sequence Analysis, DNA'] | 21,854,637 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.393.183'], ['B01.650.940.800.575.912.250.300'], ['D13.444.308.435'], ['G05.365'], ['G05.360.340.037'], ['G05.360.340.370.200'], ['G05.360.340.360'], ['G05.360.340.365'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['E0... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Small airway disease: A different phenotype of early stage COPD associated with biomass smoke exposure. | BACKGROUND AND OBJECTIVE: Chronic exposure to biomass smoke (BS) can significantly compromise pulmonary function and lead to chronic obstructive pulmonary disease (COPD). To determine whether BS exposure induces a unique phenotype of COPD from an early stage, with different physiopathological features compared with COP... | ['Aged', 'Biomass', 'Bronchi', 'Bronchoalveolar Lavage Fluid', 'Bronchoscopy', 'Case-Control Studies', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Phenotype', 'Pulmonary Disease, Chronic Obstructive', 'Smoke', 'Smoking', 'Spirometry', 'Tomography, X-Ray Computed'] | 28,906,034 | [['M01.060.116.100'], ['G16.500.275.157.100', 'N06.230.124.100'], ['A04.411.125'], ['E05.927.100.500'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Depletion of endogenous interleukin-10 augments interleukin-1 beta secretion by Mycobacterium bovis BCG-reactive human cells. | In this study, we found evidence that the interleukin-10 (IL-10) protein is functionally relevant in Mycobacterium bovis BCG-induced cytokine synthesis, as neutralization of endogenously synthesized IL-10 in human cells activated with BCG resulted in a two- to threefold increase in the level of IL-1 beta. When exogenou... | ['Adult', 'Antibodies, Monoclonal', 'Down-Regulation', 'Humans', 'In Vitro Techniques', 'Interleukin-1', 'Interleukin-10', 'Leukocytes, Mononuclear', 'Mycobacterium bovis', 'Neutralization Tests', 'Recombinant Proteins'] | 9,067,646 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Similar activation state of neutrophils in sputum of asthma patients irrespective of sputum eosinophilia. | Inflammatory phenotypes of asthma are associated with differences in disease characteristics. It is unknown whether these inflammatory phenotypes are reflected by the activation status of neutrophils in blood and sputum. We obtained peripheral blood and induced sputum from 21 asthma patients and stratified our samples ... | ['Adult', 'Aged', 'Antigens, CD', 'Antigens, Differentiation, T-Lymphocyte', 'Asthma', 'B7-H1 Antigen', 'CD11b Antigen', 'Cell Survival', 'Eosinophilia', 'Eosinophils', 'Female', 'Flow Cytometry', 'Humans', 'L-Selectin', 'Lectins, C-Type', 'Leukocyte Count', 'Male', 'Middle Aged', 'Neutrophil Activation', 'Neutrophils'... | 26,148,992 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.894', 'D23.101.100.894'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D12.776.465.625', 'D12.776.467.150.300', 'D12.776.543.095.300', 'D23.050.301.285.400', 'D23.529.168.300'], ['D12.776.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gambler Risk Perception: A Mental Model and Grounded Theory Analysis. | Few studies have investigated how gamblers perceive risk or the role of risk perception in disordered gambling. The purpose of the current study therefore was to obtain data on lay gamblers' beliefs on these variables and their effects on decision-making, behaviour, and disordered gambling aetiology. Fifteen regular la... | ['Adult', 'Behavior, Addictive', 'Deception', 'Decision Making', 'Emotions', 'Female', 'Gambling', 'Grounded Theory', 'Humans', 'Male', 'Models, Psychological', 'Motivation', 'Risk Factors', 'Risk-Taking'] | 24,402,720 | [['M01.060.116'], ['F01.145.527.100.120'], ['F01.145.813.157'], ['F02.463.785.373'], ['F01.470'], ['F01.145.722.408', 'F03.250.400'], ['H01.770.644.241.424'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F01.658', 'F01.752.543.500.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Raised plasma concentrations of endothelin-1 and -3 in marmosets with acute aortic stenosis: no relation to the renin-angiotensin system. | Plasma levels of endothelin (ET), plasma renin activity (PRA) and angiotensin II (Ang II) were measured in anaesthetized marmosets exposed to acute aortic stenosis proximal to the renal arteries. In vehicle experiments, ET rose from 5 +/- 2 to 38 +/- 4 pg ml-1, PRA from 5 +/- 2 to 99 +/- 21 ng ml-1 h-1 and Ang II from ... | ['Acute Disease', 'Angiotensin II', 'Animals', 'Aortic Valve Stenosis', 'Blood Pressure', 'Callithrix', 'Carotid Arteries', 'Chromatography, High Pressure Liquid', 'Enalaprilat', 'Endothelins', 'Female', 'Femoral Artery', 'Male', 'Osmolar Concentration', 'Renin', 'Renin-Angiotensin System'] | 1,345,144 | [['C23.550.291.125'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.988.400.600.150.150.114'], ... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of communicator weight on psychoeducational message acceptance in females with high vs. low levels of body image disturbance. | Researchers have yet to examine the effect of the communicator's weight status on participants' responses to an eating disorder or body dissatisfaction prevention program. It is plausible that participants may be reactive to the weight of the communicator (e.g., therapist), which might adversely affect acceptance of th... | ['Adolescent', 'Adult', 'Attitude', 'Body Image', 'Body Weight', 'Counseling', 'Feeding and Eating Disorders', 'Female', 'Health Education', 'Humans', 'Job Application', 'Prejudice', 'Students', 'Treatment Outcome', 'User-Computer Interface'] | 15,854,871 | [['M01.060.057'], ['M01.060.116'], ['F01.100'], ['F01.752.747.792.110', 'F02.463.593.112'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['F03.400'], ['I02.233.332', 'N02.421.726... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Detergent enema: a cause of caustic colitis. | A 5-year-old boy developed acute colitis followed by stricture formation as a result of a detergent enema. The acute phase of the caustic induced colitis was reproduced in the dog and the rat using full strength and diluted detergent enemas. The severity of the experimental colitis was shown to be directly related to t... | ['Animals', 'Child, Preschool', 'Colitis', 'Colon', 'Detergents', 'Dogs', 'Enema', 'Humans', 'Male', 'Rats'] | 927,976 | [['B01.050'], ['M01.060.406.448'], ['C06.405.205.265', 'C06.405.469.158.188'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['D27.720.877.265', 'J01.516.381'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.319.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Robot-assisted liver surgery in a general surgery unit with a "Referral Centre Hub&Spoke Learning Program". Early outcomes after our first 70 consecutive patients. | BACKGROUND: The aim of this study was to evaluate safety, feasibility and short-term outcomes of our first 70 consecutive patients treated by robotic-assisted liver resection after a reversal proctoring between a high HPB volume centre and our well-trained center in minimally invasive General Surgery. Six surgeons were... | ['Adult', 'Aged', 'Aged, 80 and over', 'Feasibility Studies', 'Female', 'Hepatectomy', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Referral and Consultation', 'Retrospective Studies', 'Robotic Surgical Procedures', 'Time Factors', 'Treatment Outcome'] | 29,795,060 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['N04.452.758.849'], ['E05.318.372.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Intestinal microbiocenosis in children with intestinal enzymopathy]. | 141 children with different kinds of intestinal enzymopathy were examined; of these, 33 had celiac disease, 39--the syndrome of celiac disease, 12--congenital lactase deficiency and 57--the syndrome of disaccharidase insufficiency. In these patients a significant decrease in the average characteristics of the main prot... | ['Celiac Disease', 'Child', 'Disaccharidases', 'Humans', 'Intestines', 'Lactase', 'Syndrome', 'beta-Galactosidase'] | 11,550,576 | [['C06.405.469.637.250', 'C18.452.603.250'], ['M01.060.406'], ['D08.811.277.450.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['D08.811.277.450.410.100.500'], ['C23.550.288.500'], ['D08.811.277.450.410.100']] | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Urinary tract infection in infants and children evaluated by ultrasound. | Fifty-nine pediatric patients with urinary tract infection (UTI) underwent renal ultrasonography, excretory urography, and voiding cystourethrography. The imaging procedures were analyzed retrospectively to determine their relative effectiveness in detecting abnormalities that might predispose the patient to UTI. Voidi... | ['Adolescent', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Kidney', 'Male', 'Retrospective Studies', 'Ultrasonography', 'Ureter', 'Urethra', 'Urinary Bladder', 'Urinary Tract', 'Urinary Tract Infections', 'Urination', 'Urography', 'Vesico-Ureteral Reflux'] | 3,880,909 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A05.810.453'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Skin disease in HIV-positive persons living in Puerto Rico. | OBJECTIVES: To determine the frequency of skin disease in persons infected with the human immunodeficiency virus (HIV), to validate the agreement of self-reported skin condition(s) versus objective data obtained by physical examination, and to describe the characteristics of HIV-positive persons with skin disease in Pu... | ['Adult', 'Female', 'HIV Infections', 'HIV Seropositivity', 'Humans', 'Male', 'Middle Aged', 'Puerto Rico', 'Skin Diseases'] | 17,473,721 | [['M01.060.116'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500', 'C20.673.480.500'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Single-stage revision from gastric band to gastric bypass or sleeve gastrectomy: 6- and 12-month outcomes. | BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) is increasingly requiring revisional surgery for complications and failures. Removal of the band and conversion to either laparoscopic Roux-en-y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG) is feasible as a single-stage procedure. The objecti... | ['Adult', 'Aged', 'Feasibility Studies', 'Female', 'Gastrectomy', 'Gastric Bypass', 'Gastroplasty', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Postoperative Complications', 'Reoperation', 'Retrospective Studies', 'Treatment Outcome', 'Weight Loss'] | 26,335,074 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E04.210.419'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['E02.650.500.062.750', 'E04.062.750', 'E04.210.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis. | Ulcerative colitis (UC) is characterized by oxidative and nitrosative stress and neutrophil infiltration. In the present study, we aimed to investigate the therapeutic effect of ginsenoside Rd (GRd) in rats with 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced recurrent UC. After UC was twice-induced by intracolonic i... | ['Animals', 'Anti-Inflammatory Agents', 'Biomarkers', 'Colitis, Ulcerative', 'Colon', 'Disease Models, Animal', 'Gastrointestinal Agents', 'Ginsenosides', 'Glutathione Peroxidase', 'Male', 'Malondialdehyde', 'Neutrophil Infiltration', 'Nitric Oxide', 'Nitric Oxide Synthase Type II', 'Oxidative Stress', 'Peroxidase', 'R... | 22,864,746 | [['B01.050'], ['D27.505.954.158'], ['D23.101'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.954.483'], ['D02.455.849.919.277', 'D09.408.782.300'], ['D08.811.682.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Malignant mesothelioma of the pleura with a large tumor embolus in the left atrium: an autopsy case. | Malignant mesothelioma of the pleura often involves the heart but seldom invades the intracardiac cavity. We report a 78-year-old woman with right pleural mesothelioma who died of heart failure. An autopsy revealed that the tumor was present at the right pleura and invaded the right upper lobe of the lung and the media... | ['Aged', 'Autopsy', 'Echocardiography', 'Fatal Outcome', 'Female', 'Heart Atria', 'Heart Neoplasms', 'Humans', 'Magnetic Resonance Imaging', 'Mediastinal Neoplasms', 'Mesothelioma', 'Neoplastic Cells, Circulating', 'Pleural Neoplasms', 'Tomography, X-Ray Computed'] | 9,711,890 | [['M01.060.116.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['A07.541.358'], ['C04.588.894.309', 'C14.280.459'], ['B01.050... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Associations of dietary patterns with bone mass, muscle strength and balance in a cohort of Australian middle-aged women. | Influences of dietary patterns on musculoskeletal health are poorly understood in middle-aged women. This cross-sectional analysis from a cohort of 347 women (aged 36-57 years) aimed to examine associations between dietary patterns and musculoskeletal health outcomes in middle-aged women. Diet was measured by the Cance... | ['Absorptiometry, Photon', 'Adult', 'Australia', 'Body Mass Index', 'Bone Density', 'Cross-Sectional Studies', 'Dairy Products', 'Diet', 'Fabaceae', 'Female', 'Femur Neck', 'Follow-Up Studies', 'Fruit', 'Humans', 'Linear Models', 'Micronutrients', 'Middle Aged', 'Muscle Strength', 'Postural Balance', 'Red Meat', 'Surve... | 28,990,541 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.300.350', 'J02.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Orbitofrontal volume deficit in schizophrenia and thought disorder. | Orbitofrontal Cortex (OFC) structural abnormality in schizophrenia has not been well characterized, probably due to marked anatomical variability and lack of consistent definitions. We previously reported OFC sulcogyral pattern alteration and its associations with social disturbance in schizophrenia, but OFC volume ass... | ['Adult', 'Brain Mapping', 'Choice Behavior', 'Female', 'Frontal Lobe', 'Gambling', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Schizophrenia', 'Schizophrenic Psychology', 'Time Factors'] | 18,056,163 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.785.373.346'], ['A08.186.211.200.885.287.500.270'], ['F01.145.722.408', 'F03.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['F04.711.513'], ['F03.700.750'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Paradoxical effects of phosphate to directly regulate the level of skeletal alkaline phosphatase activity in human osteosarcoma (SaOS-2) cells and inversely regulate the level of skeletal alkaline phosphatase mRNA. | Recent studies indicate that the amount of alkaline phosphatase (ALP) activity in human osteoblast-line cells is proportional to the concentration of phosphate in the culture medium. The current studies were intended to extend those observations and to determine whether the effects of phosphate (and phosphate esters an... | ['Alkaline Phosphatase', 'Base Sequence', 'DNA, Complementary', 'Dose-Response Relationship, Drug', 'Glycerophosphates', 'Humans', 'Molecular Sequence Data', 'Osteosarcoma', 'Phosphates', 'RNA, Messenger', 'Tumor Cells, Cultured'] | 7,736,325 | [['D08.811.277.352.650.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.800.875.750', 'D09.853.875.750', 'D09.894.299', 'D10.570.755.375'], ['B01.050.150.900.649.313.988.400.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Is There a Priority Shift in Mental Health Clinical Trials? | Mental health is the largest cost driver of healthcare. ClinicalTrials.gov is a web-based registry of trials conducted in human participants worldwide and serves as an important resource for both practice and research. We use the registry and dynamic topic modeling (DTM) methods to discover hidden topics and their evol... | ['Adolescent', 'Bipolar Disorder', 'Child', 'Clinical Trials as Topic', 'Humans', 'Mental Health', 'Registries'] | 29,295,099 | [['M01.060.057'], ['F03.084.500'], ['M01.060.406'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Echocardiography and electrocardiography as means to evaluate potential performance in horses. | Prediction of potential performance is one of the goals of exercise physiology investigations. When Selecting a horse for competition, one of the main objectives is to choose the one that predictably will reveal a competitive aptitude above the average. The horses used in this study underwent a two-dimensional echocard... | ['Animals', 'Echocardiography', 'Electrocardiography', 'Female', 'Heart', 'Horses', 'Male', 'Physical Conditioning, Animal', 'Predictive Value of Tests'] | 15,365,242 | [['B01.050'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541'], ['B01.050.150.900.649.313.984.235.472'], ['G11.427.410.698.277.280'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Lifestyle, cardiovascular risk knowledge and patient counselling among selected sub-Saharan African family physicians and trainees. | BACKGROUND: Cardiovascular disease (CVD)-related deaths in sub-Saharan Africa (SSA) are on the rise, and primary care physicians could facilitate the reversal of this trend through treatment and prevention strategies.AIM: The aim of this study was to determine the relationship between physician lifestyle practices, C... | ['Adult', 'Africa South of the Sahara', 'Cardiovascular Diseases', 'Counseling', 'Cross-Sectional Studies', 'Family Practice', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Life Style', 'Male', 'Medical Staff, Hospital', 'Middle Aged', 'Physicians, Family', "Practice Patterns, Physicians'", 'Surveys and... | 31,038,332 | [['M01.060.116'], ['Z01.058.290'], ['C14'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['H02.403.340.500'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Nutritional effects of egg shell membrane supplements on chicken performance and immunity. | Eggshell membranes (ESM) contain a variety of proteins and peptides which help in the development of embryo and provide protection to it. Many of the peptides and proteins associated with ESM have antimicrobial, immune-modulatory, and adjuvant properties. We hypothesized that the membrane byproducts from egg, provided ... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Chickens', 'Diet', 'Dietary Supplements', 'Egg Shell', 'Immunity, Innate', 'Male'] | 25,840,966 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['A13.316'], ['G12.450.564']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation. | We describe a novel protein that contains a verprolin-homology (V) region, through which several actin-regulating proteins, including Wiskott-Aldrich syndrome protein (WASP) family members, bind directly to actin. The amino acid sequence is homologous to the sequences of WASP-interacting protein (WIP) and CR16, both of... | ['Actins', 'Blotting, Western', 'Carrier Proteins', 'Cloning, Molecular', 'Cytoskeletal Proteins', 'Fungal Proteins', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Microfilament Proteins', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Organ Specificity', 'Phosphoproteins', 'Protein Binding', 'Prote... | 11,829,459 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.157'], ['E05.393.220'], ['D12.776.220'], ['D12.776.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ultrasound-enhanced optical coherence tomography: improved penetration and resolution. | Increasing penetration remains one of the most important issues in optical coherence tomography (OCT) research, which we achieved with a parallel ultrasound beam. In addition to qualitative improvements of tissue imaging, quantitative improvements in resolution of up to 28%+/-2% was noted. At lower frequencies and ener... | ['Equipment Design', 'Equipment Failure Analysis', 'Image Enhancement', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tomography, Optical Coherence', 'Ultrasonography'] | 18,382,493 | [['E05.320'], ['E05.325.192'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['E01.370.350.589.24... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Results of endoscopic ultrasonography in the preoperative assessment of rectal cancer]. | Endoscopic transrectal ultrasonography is performed with an ultrasonic transducer (7.5 MHz or 12 MHz) in the tip of a side viewing endoscope. Its accuracy to assess the depth of rectal cancer invasion was prospectively studied in 27 patients. The ultrasonic examination was correct in 23 cases; in 4 cases, the stricturi... | ['Aged', 'Endoscopy', 'Female', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Preoperative Care', 'Prospective Studies', 'Rectal Neoplasms', 'Ultrasonography'] | 2,241,075 | [['M01.060.116.100'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E01.789.625'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Strategies of schedule preference in chimpanzees. | Two chimpanzees were required to choose between a fixed-ratio schedule and a progressive-ratio schedule which increased in response requirement by 20 responses each time it was chosen. Each choice of the fixed ratio reset the progressive ratio to its minimum value. The fixed-ratio requirement was varied from 40 to 1000... | ['Animals', 'Female', 'Hominidae', 'Male', 'Motor Activity', 'Reaction Time', 'Reinforcement Schedule', 'Reinforcement, Psychology'] | 6,080,827 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400'], ['F01.145.632', 'G11.427.410.698'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.425.770.644'], ['F02.463.425.770']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Experimental infection of chickens with Ancylostoma caninum: migration and distribution of larvae in tissues. | Two hundred one-day-old male white leghorn chickens (Gallus domesticus) divided into 4 groups were inoculated with a single dose of 500, 1000, 2000 or 4000 filariform larvae of Ancylostoma caninum. Larval recoveries were made from different tissues at intervals from 4 hours to 72 hours after infection. Larval migration... | ['Ancylostoma', 'Ancylostomiasis', 'Animals', 'Chickens', 'Disease Models, Animal', 'Heart', 'Larva', 'Liver', 'Lung', 'Male', 'Muscles'] | 7,410,806 | [['B01.050.500.500.294.400.968.100.100'], ['C01.610.335.508.700.775.455.154'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A07.541'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A03.620'], ['A04.411'], ['A02.633', 'A10.690']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bilateral childhood visual impairment: child and parent concerns. | PURPOSE: To identify specific health-related quality of life and visual function concerns affecting children with bilateral visual impairment as expressed by children or one of their parents (proxy) and concerns affecting the parents themselves.METHODS: A total of 37 children <16 years of age with visual impairment (vi... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Health Status', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Parents', 'Prospective Studies', 'Psychology, Child', 'Quality of Life', 'Sickness Impact Profile', 'Surveys and Questionnaires', 'Vision Disorders', 'Visually Impaired Persons', 'Young Adult'] | 28,527,654 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.372.500.750.625', 'N05.715.360.3... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Clinical effects of nitrous oxide and oxygen mixtures at sea-level and at 1700 metres altitude. | The effects of nitrous oxide, at sea-level and at an altitude of 1700 m, were assessed on a subjective and objective basis. Only marginal differences were shown between the effects of the gas at sea-level and 1700 m. Since consciousness was impaired with 60 and 70% nitrous oxide it is suggested that the use of Entonox-... | ['Adult', 'Altitude', 'Anesthesia, Inhalation', 'Consciousness', 'Humans', 'Nitrous Oxide', 'Oxygen'] | 532,921 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Experiences with perioperative short-term prevention in thoracic wall and colorectal surgery in children]. | This is a report on prophylaxis with antibiotics in chest wall deformities and colorectal surgery in childhood. The analysis shows a significant reduction of wound infections and general infections after administration of Cefamandol (150 mg/kg in 4 doses) or Cefotaxim (100 mg/kg in 3 doses) and Metronidazol (25 mg/kg i... | ['Anti-Bacterial Agents', 'Child', 'Colon', 'Humans', 'Premedication', 'Rectum', 'Surgical Wound Infection', 'Thoracic Surgery'] | 6,730,698 | [['D27.505.954.122.085'], ['M01.060.406'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.703'], ['A03.556.124.526.767', 'A03.556.249.249.767'], ['C01.947.692', 'C23.550.767.925'], ['H02.403.810.803']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Asymmetric autocatalysis of pyrimidyl alkanol and its application to the study on the origin of homochirality. | CONSPECTUS: Amplification of enantiomeric excess (ee) is a key feature for the chemical evolution of biological homochirality from the origin of chirality. We describe the amplification of ee in the asymmetric autocatalysis of 5-pyrimidyl alkanols in the reaction between diisopropylzinc (i-Pr2Zn) and pyrimidine-5-carba... | ['Alcohols', 'Aldehydes', 'Catalysis', 'Molecular Structure', 'Pyrimidines', 'Stereoisomerism'] | 25,511,374 | [['D02.033'], ['D02.047'], ['G02.130'], ['G02.111.570', 'G02.466'], ['D03.383.742'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fasciculation potentials in high-density surface EMG. | Fasciculation potentials (FPs) are observed in healthy individuals, but also in patients with neurogenic disorders. The exact site of origin and the clinical relevance in distinguishing, for example, amyotrophic lateral sclerosis (ALS) from other neurogenic diseases based on specific characteristics of the FPs is still... | ['Amyotrophic Lateral Sclerosis', 'Electric Stimulation', 'Electrodes', 'Electromyography', 'Evoked Potentials, Motor', 'Fasciculation', 'Humans', 'Male', 'Neural Conduction'] | 17,545,837 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['E05.723.402'], ['E07.305.250'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['C10.597.613.250', 'C23.888.592.608.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oral efficacy of a leukotriene B4 receptor antagonist in colitic cotton-top tamarins. | Leukotriene B4 (LTB4) is a potent neutrophil activator and chemotaxin that is present in increased concentrations in the colonic tissue and rectal dialysates of acute ulcerative colitis patients. Cotton-top tamarins (CTTs) with confirmed active colitis were treated with the second generation LTB4 receptor antagonist, S... | ['Animals', 'Feces', 'Inflammatory Bowel Diseases', 'Intestine, Large', 'Leukotriene B4', 'Monkey Diseases', 'Saguinus'] | 8,549,949 | [['B01.050'], ['A12.459'], ['C06.405.205.731', 'C06.405.469.432'], ['A03.556.124.526', 'A03.556.249.249'], ['D10.251.355.255.100.450.411', 'D10.251.355.310.166.887.411', 'D23.469.050.175.450.415'], ['C22.735.500'], ['B01.050.150.900.649.313.988.400.600.150.150.710']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Compositional Analysis of Genetically Engineered GR2E "Golden Rice" in Comparison to That of Conventional Rice. | Compositional analyses were performed on samples of rice grain, straw, and derived bran obtained from golden rice event GR2E and near-isogenic control PSBRc82 rice grown at four locations in the Philippines during 2015 and 2016. Grain samples were analyzed for key nutritional components, including proximates, fiber, po... | ['Amino Acids', 'Bangladesh', 'Fatty Acids', 'Food, Genetically Modified', 'Genetic Engineering', 'Nutritive Value', 'Oryza', 'Philippines', 'Plant Proteins', 'Plants, Genetically Modified', 'Provitamins', 'Seeds', 'Vitamin A', 'beta Carotene'] | 31,282,158 | [['D12.125'], ['Z01.252.245.131'], ['D10.251'], ['G07.203.300.518', 'J02.500.518'], ['E05.393.420'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.850.601.750'], ['B01.650.940.800.575.912.250.822.616'], ['Z01.252.145.671', 'Z01.639.790'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['D27.505.696.494.600.354'... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Direct transmission of the cat flea (Ctenocephalides felis) between cats exhibiting social behaviour. | A study design was created to assess the potential for fleas to infest cats directly from other cats. In the first experiment, six cats were infested with 100 fleas each and then immediately put in contact with six flea-free cats for 24 h. After removal of all fleas the study was repeated and the contact between cats l... | ['Animals', 'Cat Diseases', 'Cats', 'Ctenocephalides', 'Female', 'Flea Infestations', 'Male', 'Sex Factors', 'Social Behavior'] | 24,309,021 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.500.131.617.720.500.500.968.200'], ['C01.610.858.211.250'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.813']] | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Smelling the metal: Volatile organic compound emission under Zn excess in the mint Tetradenia riparia. | This work investigated the effect of Zn excess on growth, metal accumulation and photosynthetic changes in Tetradenia riparia, in relation to possible variations in the composition of the plant volatilome. Experiments were carried out in hydroponics exposing plants to a range of Zn concentrations. Zinc excess negativel... | ['Carotenoids', 'Chlorophyll', 'Lamiaceae', 'Photosynthesis', 'Plant Leaves', 'Volatile Organic Compounds', 'Zinc'] | 29,650,146 | [['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['B01.650.940.800.575.912.250.583.520'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microbial coexistence through chemical-mediated interactions. | Many microbial functions happen within communities of interacting species. Explaining how species with disparate growth rates can coexist is important for applications such as manipulating host-associated microbiota or engineering industrial communities. Here, we ask how microbes interacting through their chemical envi... | ['Brevibacillus', 'Escherichia coli', 'Microbial Interactions', 'Microbiota', 'Models, Biological', 'Staphylococcus'] | 31,053,707 | [['B03.300.390.400.160', 'B03.353.500.117', 'B03.510.100.117', 'B03.510.415.400.179', 'B03.510.460.410.165'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G06.550'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['E05.599.395'], ['B03.300.390.400.800.750', 'B03.353.500.750.750', 'B... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Seizure after intrathecal baclofen bolus in a multiple sclerosis patient treated with oxcarbazepine. | Epileptic seizures associated with intrathecal baclofen (ITB) application have been observed in patients with traumatic brain injury. A higher incidence of seizures has also been reported in patients with multiple sclerosis (MS) receiving ITB. To our knowledge, no case of a first epileptic seizure has been reported in ... | ['Adult', 'Anticonvulsants', 'Antipsychotic Agents', 'Baclofen', 'Benzodiazepines', 'Carbamazepine', 'Female', 'GABA-B Receptor Agonists', 'Humans', 'Injections, Spinal', 'Multiple Sclerosis, Chronic Progressive', 'Olanzapine', 'Oxcarbazepine', 'Seizures'] | 20,607,336 | [['M01.060.116'], ['D27.505.954.427.080'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D02.241.081.114.500.350.100'], ['D03.633.100.079.080'], ['D03.633.300.240.127'], ['D27.505.519.625.240.200.750', 'D27.505.696.577.240.200.750'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The clinical value of Vav3 in peripheral blood for predicting lymphatic metastasis of gastric cancer. | BACKGROUND: Overexpression of Vav3, a gene involved in signal transduction, promotes invasion and inhibits apoptosis in several cancers. The clinical value of the protein product of this gene, Vav3, in the peripheral blood of gastric cancer patients is unknown. We hypothesised increased serum Vav3 that related to tissu... | ['Case-Control Studies', 'Female', 'Humans', 'Intercellular Adhesion Molecule-1', 'Lymphatic Metastasis', 'Male', 'Matrix Metalloproteinase 7', 'Middle Aged', 'Proto-Oncogene Proteins c-vav', 'Stomach Neoplasms', 'rac1 GTP-Binding Protein'] | 28,513,273 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.200.450', 'D12.776.543.550.200.450', 'D23.050.301.350.450'], ['C04.697.650.560', 'C23.550.727.650.560'], ['D08.811.277.656.300.480.525.700.250', 'D08.811.277.656.675.374.525... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial. | CONTEXT: Percutaneous coronary revascularization of small vessels is associated with a high restenosis rate. Sirolimus-eluting stents reduce restenosis in simple and previously untreated lesions of large coronary arteries, but their outcomes in small vessels have not been adequately investigated.OBJECTIVE: To determine... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Coronary Artery Disease', 'Coronary Restenosis', 'Drug Delivery Systems', 'Female', 'Humans', 'Immunosuppressive Agents', 'Male', 'Middle Aged', 'Prospective Studies', 'Radiography', 'Single-Blind Method', 'Sirolimus', 'Stents'] | 15,585,732 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C14.280.647.250.285.200... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The role of corticosteroid therapy following surgery for atrial fibrillation. | BACKGROUND: The objective of our study was to evaluate the usefulness of steroids therapy for patients who underwent surgery for chronic atrial fibrillation, with histologic findings of myocarditis.METHODS: Between April 1991 and July 2002, 144 patients underwent surgery for chronic atrial fibrillation at the time of o... | ['Adrenal Cortex Hormones', 'Amiodarone', 'Anti-Arrhythmia Agents', 'Atrial Fibrillation', 'Catheter Ablation', 'Electric Countershock', 'Female', 'Heart Valve Prosthesis Implantation', 'Humans', 'Methylprednisolone', 'Middle Aged', 'Mitral Valve Stenosis', 'Myocardial Contraction', 'Postoperative Complications', 'Recu... | 15,151,650 | [['D06.472.040'], ['D03.633.100.127.075'], ['D27.505.954.411.097'], ['C14.280.067.198', 'C23.550.073.198'], ['E02.808.750.500', 'E04.014.760.500'], ['E02.331.350'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.432.769.795.539'], ['M01.060.116.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
High-density lipoprotein-cholesterol and antipsychotic medication in overweight inpatients with schizophrenia: post-hoc analysis of a Japanese nationwide survey. | BACKGROUND: Patients with schizophrenia have an increased prevalence of metabolic disturbances compared with the general population. However, the mechanisms underlying the metabolic side effects of antipsychotics are unknown. The aim of the present study was to compare the levels of high-density lipoprotein (HDL)-chole... | ['Adult', 'Aged', 'Antipsychotic Agents', 'Aripiprazole', 'Body Mass Index', 'Cholesterol, HDL', 'Correlation of Data', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Olanzapine', 'Overweight', 'Prevalence', 'Risperidone', 'Schizophrenia', 'Surveys and Questionnaires', 'Waist Circumference'] | 29,879,941 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D03.383.606.170', 'D03.633.100.810.835.122'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D04.210.500.247.808.197.238', 'D10.532.432.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Spatial and temporal sensitivity degradation of primary visual cortical cells in senescent rhesus monkeys. | Human visual function declines with age. Much of this decline is mediated by changes in the central visual pathways. In this study we compared the spatial and temporal sensitivities of striate cortical cells in young and old paralysed macaque monkeys. Extracellular single-unit recordings were employed. Our results show... | ['Aging', 'Animals', 'Cerebral Cortex', 'Humans', 'Macaca mulatta', 'Photic Stimulation', 'Vision, Ocular', 'Visual Pathways', 'Visual Perception'] | 18,616,566 | [['G07.345.124'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['E05.723.729'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935'], ['A08.612.220.860'], ['F02.463.593.932']... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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