Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Myelopathy due to hypoplasia of the atlas. A case report. | The authors report a 73-year-old woman who had spinal cord compression develop because of hypoplasia of the atlas associated with a retroodontoid pseudotumor diagnosed by magnetic resonance imaging. Radiographs of the cervical spine showed narrowing of the spinal canal at the level of the atlas and severe osteoarthrosi... | ['Aged', 'Cervical Atlas', 'Cervical Vertebrae', 'Female', 'Humans', 'Laminectomy', 'Magnetic Resonance Imaging', 'Remission, Spontaneous', 'Spinal Cord Compression', 'Spinal Fusion', 'Spinal Neoplasms', 'Tomography, X-Ray Computed'] | 9,170,367 | [['M01.060.116.100'], ['A02.835.232.834.151.500'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['E01.370.350.825.500'], ['C23.550.291.656.700', 'G16.767'], ['C10.228.854.761', 'C26.819.678'], ['E04.555.100.700'], ['C04.588.149.8... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An evaluation of the effectiveness of a recirculating laboratory hood. | Ductless, benchtop hoods have become a popular tool for use in the control of toxic substances in the laboratory. Low price and ease of installation are major factors contributing to their increased utilization. Little objective performance data exist for these devices. One such hood was evaluated for efficacy as an en... | ['Air Pollution', 'Equipment and Supplies', 'Evaluation Studies as Topic', 'Filtration', 'Humans', 'Laboratories'] | 3,946,196 | [['N06.850.460.100'], ['E07'], ['E05.337', 'N05.715.360.335'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J03.520', 'N02.278.487']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Control of the micromovements of a composite-material nail design: A finite element analysis. | BACKGROUND: Intramedullary nail fixation is the most accepted modality for stabilizing long bone midshaft fractures. The commercially used nails are fabricated from Stainless Steel or Titanium. Composite-materials (CM) mainly carbon-fiber reinforced polymers (CFRP) have been gaining more interest and popularity due to ... | ['Bone Nails', 'Carbon', 'Femur', 'Finite Element Analysis', 'Motion', 'Polymers', 'Prosthesis Design'] | 26,476,965 | [['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['D01.268.150'], ['A02.835.232.043.150'], ['E05.355'], ['G01.482'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.320.550', 'E07.695.680']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Identification of lymphoid cells in cultured of murine leukocytes and thymus. | Several culture conditions and media were studied in an effort to establish long-term cultures of murine lymphoid cells from blood and thymus. Cultures vessels included small glass bottles and rubber-stoppered tubes. Media such as Roswell Park Memorial Institute 1640, 1700, 1701, 1715, GEM 1717, NCTC, fetal calf and h... | ['Animals', 'Cell Line', 'Cell Nucleus', 'Cells, Cultured', 'Chromosomes', 'Culture Media', 'Epitopes', 'Fluorescent Antibody Technique', 'Immunoglobulins', 'Karyotyping', 'Leukocytes', 'Lymphocyte Activation', 'Lymphocyte Culture Test, Mixed', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Neop... | 46,778 | [['B01.050'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['D27.720.470.305', 'E07.206'], ['D23.050.550'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.2... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postnatal development of the inferior olivary complex in the rat. I. An electron microscopic study of the medial accessory olive. | The postnatal development of the medial accessory olive (MAO) was studied in the rat from birth to adulthood. In newborn rats, the inferior olivary complex exhibited an adult cytoarchitectonic pattern, facilitating the precise delimitation of the MAO. Computer-assisted measurements of neuronal perikarya in 1 micron thi... | ['Animals', 'Animals, Newborn', 'Cell Differentiation', 'Cerebellum', 'Dendrites', 'Microscopy, Electron', 'Nerve Fibers', 'Neural Pathways', 'Olivary Nucleus', 'Purkinje Cells', 'Rats', 'Rats, Inbred Strains', 'Synapses', 'Synaptic Transmission', 'Synaptic Vesicles'] | 6,307,487 | [['B01.050'], ['B01.050.050.282'], ['G04.152'], ['A08.186.211.132.810.428.200'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.675.542', 'A11.671.501'], ['A08.612'], ['A08.186.211.132.810.591.500.574'], ['A08.186.211.132.810.428.200.212.600', 'A08.675.784', 'A11.671.78... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Network analysis of toxic chemicals and symptoms: implications for designing first-responder systems. | The rapid and accurate identification of toxic chemicals is critical for saving lives in emergency situations. However, first-responder systems such as WISER typically require a large number of inputs before a chemical can be identified. To address this problem, we used networks to visualize and analyze the complex rel... | ['Algorithms', 'Audiovisual Aids', 'Databases as Topic', 'Decision Support Techniques', 'Emergency Medical Service Communication Systems', 'Emergency Medical Services', 'Hazardous Substances', 'Humans'] | 18,693,796 | [['G17.035', 'L01.224.050'], ['J01.897.280.500', 'L01.178.820.090'], ['L01.313.500.750.300.188', 'L01.470.750'], ['E05.245', 'L01.313.500.750.190'], ['N02.421.297.058'], ['N02.421.297'], ['D27.888.426'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Seeking help despite the stigma: Experiential avoidance as a moderated mediator. | The help-seeking literature identifies a model wherein public stigma of seeking help is internalized as self-stigma of seeking help, which, in turn, decreases help-seeking outcomes. The current study considered whether experiential avoidance, or a tendency to avoid painful thoughts or emotions, moderates how strongly t... | ['Adolescent', 'Avoidance Learning', 'Female', 'Humans', 'Intention', 'Male', 'Negotiating', 'Patient Acceptance of Health Care', 'Social Stigma', 'Surveys and Questionnaires', 'Young Adult'] | 31,343,214 | [['M01.060.057'], ['F02.463.425.097', 'F02.463.785.373.173'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['F01.145.209.520', 'F01.829.401.520', 'F02.463.785.373.520', 'L01.143.620', 'N04.452.677.430'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500'], ['F01.145... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration. | Panax ginseng is becoming a promising antidiabetic herbal medication. As the main active constituents of Panax ginseng, ginsenosides are well known, poorly absorbed chemicals. However, the pharmacokinetic behavior of ginsenosides under diabetic conditions is not fully understood. This study aimed to explore the alterat... | ['Administration, Oral', 'Animals', 'Caco-2 Cells', 'Diabetes Mellitus, Experimental', 'Dogs', 'Ginsenosides', 'Glycosylation', 'Humans', 'Intestinal Absorption', 'Jejunum', 'Madin Darby Canine Kidney Cells', 'Male', 'Panax', 'Permeability', 'Rats', 'Rats, Sprague-Dawley'] | 26,265,741 | [['E02.319.267.100'], ['B01.050'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.455.849.919.277', 'D09.408.782.300'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Norepinephrine depresses the capsaicin-evoked miniature excitatory postsynaptic currents in substantia gelatinosa of the rat spinal cord. | Capsaicin selectively excites nociceptive primary afferent fibers and increases the frequency of glutaminergic miniature excitatory postsynaptic currents (mEPSCs) in the substantia gelatinosa of the spinal dorsal horn. The whole-cell voltage-clamp recording technique was used to examine the effect of norepinephrine (NE... | ['Adrenergic alpha-Agonists', 'Animals', 'Capsaicin', 'Excitatory Postsynaptic Potentials', 'Male', 'Neural Inhibition', 'Norepinephrine', 'Patch-Clamp Techniques', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord', 'Substantia Gelatinosa'] | 11,958,853 | [['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['B01.050'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated DNA damage and inactivation of the ERK pathway. | 5-Fluorouracil (5-FU)-based chemotherapy as a first-line treatment is quite limited, because of its inefficiency and clinical resistance to it. The search for chemosensitizers that could augment its efficiency and overcome the drug resistance to 5-FU has kindled great interest among scientists. Selenocystine (SeC), a n... | ['Antineoplastic Agents', 'Apoptosis', 'Blotting, Western', 'Cell Line, Tumor', 'Cell Survival', 'Chromatography, High Pressure Liquid', 'Cystine', 'DNA Damage', 'Drug Synergism', 'Fluorouracil', 'Humans', 'In Situ Nick-End Labeling', 'MAP Kinase Signaling System', 'Membrane Potential, Mitochondrial', 'Organoselenium C... | 23,837,948 | [['D27.505.954.248'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['E05.196.181.400.300'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Utility of novel 3-dimensional stereoscopic vision system for endoscopic sinonasal and skull-base surgery. | BACKGROUND: The objective of this pilot study was to evaluate the utility of novel 3-dimensional (3D) endoscopy during endoscopic sinonasal and skull base surgery.METHODS: Eight surgeries were performed in 7 patients between August 2009 and March 2010 at a tertiary care academic medical center. A high-definition 2-dime... | ['Adult', 'Aged', 'Endoscopes', 'Endoscopy', 'Equipment Design', 'Female', 'Fibrous Dysplasia of Bone', 'Humans', 'Imaging, Three-Dimensional', 'Intraoperative Care', 'Male', 'Middle Aged', 'Mycoses', 'Paranasal Sinus Neoplasms', 'Pilot Projects', 'Rhinitis, Allergic, Perennial', 'Sinusitis', 'Skull Base', 'Video-Assis... | 22,287,372 | [['M01.060.116'], ['M01.060.116.100'], ['E07.230.220', 'E07.858.240'], ['E01.370.388.250', 'E04.502.250'], ['E05.320'], ['C05.116.099.708.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['M01.060.116.630'], ['C01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
What makes the learning of physiology in a PBL medical curriculum challenging? Student perceptions. | Physiology is an integral component of any medical curriculum. Traditionally, the learning of physiology has relied heavily on systems-based didactic lectures. In 2001, the Nelson R. Mandela School of Medicine (NRMSM; Durban, South Africa) embarked on a problem-based curriculum in which the learning of physiology was i... | ['Curriculum', 'Education, Medical', 'Humans', 'Learning', 'Physiology', 'Students, Medical', 'Surveys and Questionnaires'] | 19,745,044 | [['I02.158'], ['I02.358.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['H01.158.782'], ['M01.848.769.602'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stability. | Various topological constraints at the ribosomal DNA (rDNA) locus impose an extra challenge for transcription and DNA replication, generating constant torsional DNA stress. The topoisomerase Top1 is known to release such torsion by single-strand nicking and re-ligation in a process involving transient covalent Top1 cle... | ['DNA Breaks, Double-Stranded', 'DNA Cleavage', 'DNA Replication', 'DNA Topoisomerases, Type I', 'DNA, Ribosomal', 'DNA-Binding Proteins', 'Intracellular Signaling Peptides and Proteins', 'Protein Stability', 'RecQ Helicases', 'Saccharomyces cerevisiae Proteins'] | 24,574,527 | [['G05.200.210.220'], ['G02.111.210', 'G05.193'], ['G02.111.225', 'G05.226'], ['D08.811.399.403.483', 'D12.776.157.687.375', 'D12.776.660.720.375'], ['D13.444.308.475'], ['D12.776.260'], ['D12.644.360', 'D12.776.476'], ['G02.111.700'], ['D08.811.277.040.025.159.249', 'D08.811.399.340.249'], ['D12.776.354.750']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA stemline heterogeneity of non-small cell lung carcinomas and differences in DNA ploidy between carcinomas and metastatic nodes. | Nuclear DNA contents were measured using a flow cytometry technique in non-small cell lung carcinomas and differences in ploidy patterns were compared between primary lung carcinomas and metastatic lymph nodes. Negative node lung cancer revealed diploidy in 82.6% of the 224 non-small cell lung cancers, in contrast with... | ['Adenocarcinoma', 'Aged', 'Aneuploidy', 'Carcinoma, Large Cell', 'Carcinoma, Non-Small-Cell Lung', 'Carcinoma, Squamous Cell', 'DNA, Neoplasm', 'Diploidy', 'Genetic Heterogeneity', 'Humans', 'Lung Neoplasms', 'Lymph Nodes', 'Lymphatic Metastasis', 'Mediastinum', 'Middle Aged', 'Ploidies', 'Predictive Value of Tests', ... | 7,812,698 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C04.557.470.200.260'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D13.444.308.425'], ['G05.700.264'], ['G05.365.331'],... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of pheromone and plant volatile release rates and ratios on trapping Anoplophora glabripennis (Coleoptera: Cerambycidae) in China. | Native to China and Korea, the Asian longhorned beetle, Anoplophora glabripennis (Motschulsky) (Coleoptera: Cerambycidae), is a polyphagous wood-boring pest for which a trapping system would greatly benefit eradication and management programs in both the introduced and native ranges. Over two field seasons, a total of ... | ['Animals', 'China', 'Coleoptera', 'Dose-Response Relationship, Drug', 'Female', 'Insect Control', 'Male', 'Pheromones', 'Seasons', 'Volatile Organic Compounds'] | 25,259,696 | [['B01.050'], ['Z01.252.474.164'], ['B01.050.500.131.617.720.500.500.375'], ['G07.690.773.875', 'G07.690.936.500'], ['N06.850.780.200.650.425'], ['D23.641'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['D02.974']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Acetylated alpha-tubulin in Physarum: immunological characterization of the isotype and its usage in particular microtubular organelles. | We have used monoclonal antibodies specific for acetylated and unacetylated alpha-tubulin to characterize the acetylated alpha-tubulin isotype of Physarum polycephalum, its expression in the life cycle, and its localization in particular microtubular organelles. We have used the monoclonal antibody 6-11B-1 (Piperno, G.... | ['Acetylation', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Cell Compartmentation', 'Cell Differentiation', 'Fluorescent Antibody Technique', 'Microtubules', 'Physarum', 'Protein Processing, Post-Translational', 'Tubulin'] | 3,539,947 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['G04.128'], ['G04.152'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The stimulation of rat liver microsomal CDP-diacylglycerol formation by guanosine triphosphate. | GTP has been found to markedly enhance the formation of CDP-diacylglycerol in rat liver microsomes. Neither GDP, GMP nor the nonhydrolyzable analogues of GTP increased the synthesis of the liponucleotide. The GTP stimulation of phosphatidate cytidylyltransferase activity is inhibited by EDTA and NaF. GTP enhances the a... | ['Animals', 'Cytidine Diphosphate Diglycerides', 'Enzyme Activation', 'Guanosine Diphosphate', 'Guanosine Monophosphate', 'Guanosine Triphosphate', 'Kinetics', 'Microsomes, Liver', 'Nucleoside Diphosphate Sugars', 'Nucleotidyltransferases', 'Rats', 'Ribonucleotides', 'Structure-Activity Relationship'] | 6,257,345 | [['B01.050'], ['D03.383.742.686.246.150.210', 'D09.408.620.569.200', 'D13.695.740.246.150.210', 'D13.695.827.232.150.210', 'D13.695.827.708.260'], ['G02.111.263', 'G03.328'], ['D03.633.100.759.646.454.340', 'D13.695.667.454.340', 'D13.695.827.426.340'], ['D03.633.100.759.646.454.400', 'D13.695.667.454.400', 'D13.695.82... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute cerebral blood flow variations after human cardiac arrest assessed by stable xenon enhanced computed tomography. | In this study, changes in cerebral blood flow (CBF) during acute phase after cardiopulmonary arrest (CPA) were examined in patients using stable Xenon enhanced computed tomography (Xe-CT). All patients (8) were stabilized hemodynamically within 4 hours after admission, and Xe-CT was performed immediately after restorat... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Cerebrovascular Circulation', 'Female', 'Heart Arrest', 'Humans', 'Hypoxia, Brain', 'Male', 'Middle Aged', 'Pilot Projects', 'Prognosis', 'Recovery of Function', 'Tomography, X-Ray Computed', 'Xenon'] | 17,311,544 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G09.330.100.159'], ['C14.280.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.624', 'C23.888.852.079.797'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E01.789... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cross-sectional analysis of a large cohort with X-linked Charcot-Marie-Tooth disease (CMTX1). | OBJECTIVE: To extend the phenotypic description of Charcot-Marie-Tooth disease (CMTX1) and to draw new genotype-phenotype relationships.METHODS: Mutations in GJB1 cause the main X-linked form of CMTX (CMTX1). We report cross-sectional data from 160 patients (from 120 different families, with 89 different mutations) see... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Amino Acid Sequence', 'Charcot-Marie-Tooth Disease', 'Child', 'Connexins', 'Cross-Sectional Studies', 'Family', 'Female', 'Genetic Association Studies', 'Genotyping Techniques', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Neural Conduction', 'Phenotype', 'Sex Char... | 28,768,847 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['M01.060.406'], ['D12.776.543.585.250'], ['E05.318.372.500.875', 'N05.715.360... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Stable isotope labeling by amino acids in cell culture (SILAC) and quantitative comparison of the membrane proteomes of self-renewing and differentiating human embryonic stem cells. | Stable isotope labeling by amino acids in cell culture (SILAC) is a powerful quantitative proteomics platform for comprehensive characterization of complex biological systems. However, the potential of SILAC-based approaches has not been fully utilized in human embryonic stem cell (hESC) research mainly because of the ... | ['Amino Acids', 'Animals', 'Biomarkers', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Culture Media, Conditioned', 'Embryonic Stem Cells', 'Gene Expression Regulation, Developmental', 'Humans', 'Isotope Labeling', 'Membrane Proteins', 'Mice', 'Phosphoproteins', 'Pluripotent Stem Cells', 'Proteome',... | 19,151,416 | [['D12.125'], ['B01.050'], ['D23.101'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['A11.872.700.250'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.522'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.74... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Localization of ganglioside 9-O-acetyl GD3 in point contacts of neuronal growth cones. | Gangliosides are a large group of sialylated glycosphingolipids widely expressed in mammalian tissues. We have shown previously that the expression of 9-O-acetyl GD3 is highly correlated with periods of neurite outgrowth in the developing nervous system, and that the advance of dorsal root ganglia growth cones on lamin... | ['Animals', 'Embryo, Mammalian', 'Female', 'Ganglia, Spinal', 'Gangliosides', 'Growth Cones', 'Immunohistochemistry', 'Integrin beta1', 'Microscopy, Confocal', 'Neurites', 'Pregnancy', 'Rats', 'Vinculin'] | 12,973,826 | [['B01.050'], ['A16.254'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['D09.400.410.420.025.475', 'D10.390.470.025.475', 'D10.570.877.360.025.475'], ['A11.284.180.075.249', 'A11.284.180.225.340', 'A11.284.180.610.345', 'A11.671.137.340', 'A11.671.240.340'], ['E01.370.225.500.607.512', 'E01.370.2... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Strategic Materials in the Automobile: A Comprehensive Assessment of Strategic and Minor Metals Use in Passenger Cars and Light Trucks. | A comprehensive component-level assessment of several strategic and minor metals (SaMMs), including copper, manganese, magnesium, nickel, tin, niobium, light rare earth elements (LREEs; lanthanum, cerium, praseodymium, neodymium, promethium, and samarium), cobalt, silver, tungsten, heavy rare earth elements (yttrium, e... | ['Automobiles', 'Canada', 'Japan', 'Lanthanum', 'Metals', 'Neodymium', 'Praseodymium'] | 29,120,610 | [['J01.937.500.100'], ['Z01.107.567.176'], ['Z01.252.474.463', 'Z01.639.595'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['D01.552'], ['D01.268.558.362.625', 'D01.552.550.399.625'], ['D01.268.558.362.750', 'D01.552.550.399.750']] | ['Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Antiphospholipid syndrome in Mexican children. | BACKGROUND: Data on pediatric antiphospholipid syndrome (APS) are very sparse.OBJECTIVES: To describe the main clinical characteristics, laboratory data and complications of pediatric APS patients, and to analyze the differences between primary APS and APS associated with systemic lupus erythematosus (SLE).METHODS: We ... | ['Age of Onset', 'Antiphospholipid Syndrome', 'Chi-Square Distribution', 'Child', 'Female', 'Humans', 'Male', 'Mexico', 'Registries', 'Retrospective Studies'] | 22,799,058 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['C20.111.197'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.589'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.85... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
New combination therapy of gliclazide and quercetin for protection against STZ-induced diabetic rats. | AIMS: The use of natural agents with anti-diabetic effect in combination therapy adds further positive clinical implications in the management of diabetes mellitus. Interestingly, quercetin is one of the most potent naturally occurring antioxidant which possesses various pharmacological actions including anti-diabetic ... | ['Animals', 'Blood Glucose', 'C-Peptide', 'Cholesterol', 'Diabetes Mellitus, Experimental', 'Drug Therapy, Combination', 'Gliclazide', 'Glutathione', 'Hypoglycemic Agents', 'Inflammation', 'Insulin', 'Islets of Langerhans', 'Male', 'Malondialdehyde', 'NF-kappa B', 'Oxidative Stress', 'Pancreas', 'Quercetin', 'Rats', 'R... | 32,092,333 | [['B01.050'], ['D09.947.875.359.448.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['E02.319.310'], ['D02.065.950.828.475', 'D02.886.590.795.475'], ['D12.644.456.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement: report of 2 cases. | Desmoplastic fibroma (DF) is a rare bone tumor that accounts for about 0.1%-0.3% of all bone tumors. It is typically characterized as slow growing, but in rare cases it can proliferate extensively and exhibit locally aggressive characteristics. It is found most commonly in the appendicular skeleton and rarely in the ax... | ['Brachial Plexus', 'Brachial Plexus Neuropathies', 'Female', 'Fibroma, Desmoplastic', 'Humans', 'Mediastinal Diseases', 'Mediastinum', 'Spinal Neoplasms', 'Young Adult'] | 23,952,324 | [['A08.800.800.720.050'], ['C10.668.829.100'], ['C04.557.450.565.590.340.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.846.187'], ['A01.923.761.800.500'], ['C04.588.149.828', 'C05.116.231.828', 'C05.116.900.801'], ['M01.060.116.815']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Central metabolic fluxes in the endosperm of developing maize seeds and their implications for metabolic engineering. | ?⁴C labeling experiments performed with kernel cultures showed that developing maize endosperm is more efficient than other non-photosynthetic tissues such as sunflower and maize embryos at converting maternally supplied substrates into biomass. To characterize the metabolic fluxes in endosperm, maize kernels were labe... | ['Carbon Isotopes', 'Computer Simulation', 'Endosperm', 'Gene Targeting', 'Metabolic Clearance Rate', 'Models, Biological', 'Plant Proteins', 'Plants, Genetically Modified', 'Protein Engineering', 'Signal Transduction', 'Zea mays'] | 20,969,971 | [['D01.268.150.075', 'D01.496.123'], ['L01.224.160'], ['A18.024.500.750.666'], ['E05.393.335'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['E05.599.395'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['E05.393.420.601'], ['G02.111.820', 'G04.835'], ['B01.650.940.800.575.912.25... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Urinary stones and Crohn's disease. | Urinary stones, renal and bladder, are common in the general population of the United States. The pathophysiology of Crohn's disease and therapeutic interventions can contribute to the development of kidney stones usually secondary to malabsorption. Knowledge of these effects is important when caring for patients with ... | ['Crohn Disease', 'Humans', 'Male', 'Middle Aged', 'Urinary Calculi'] | 16,438,252 | [['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.777.967.500', 'C13.351.968.967.500', 'C23.300.175.850']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The role of integrins in granulocyte dysfunction in myelodysplastic syndrome. | The aim of the present study was to evaluate the function of granulocytes in 20 patients affected by myelodysplastic syndrome (MDS) and correlate this with the expression of surface membrane integrins. The granulocytes showed a deficit in chemotaxis (34 +/- 12 vs 84 +/- 10, p < 0.01) in superoxide release (12 +/- 7 vs ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Monoclonal', 'Cell Aggregation', 'Cell Membrane', 'Chemotaxis, Leukocyte', 'Female', 'Follow-Up Studies', 'Granulocytes', 'Humans', 'Integrins', 'Male', 'Middle Aged', 'Myelodysplastic Syndromes', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Stimulation,... | 8,326,743 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.198.251'], ['A11.284.149'], ['G04.198.424.233'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A11.118.637.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Color preferences in infants and adults are different. | Adults commonly prefer blues most and greenish yellows least, but these hue preferences interact with lightness and saturation (e.g., dark yellow is particularly disliked: Palmer & Schloss (Proceedings of the National Academy of Sciences 107:8877-8882, 2010)). Here, we tested for a similar hue-by-lightness interaction ... | ['Adult', 'Age Factors', 'Child Development', 'Choice Behavior', 'Color Perception', 'Female', 'Humans', 'Infant', 'Male', 'Young Adult'] | 23,435,629 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.785.373.346'], ['F02.463.593.932.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.815']] | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Antioxidants, prostaglandins and prematurity]. | Preterm labor could have very bad consequences for the new-born. Every method which maintain pregnancy till term deserves to be analyzed. Such an analysis could throw a light on the process of parturition and open therapeutic possibilities against prematurity. Once a food-stuff antioxidant, Diphenyl-p-Phenylene-Diamine... | ['Animals', 'Antioxidants', 'Female', 'Obstetric Labor, Premature', 'Pregnancy', 'Prostaglandins', 'Rats', 'Rats, Wistar'] | 9,673,054 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C13.703.420.491'], ['G08.686.784.769'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors influencing prognosis of patients with CNS supratentorial astroglial tumors who underwent postoperative radiotherapy. | To find the association between survival and various prognostic factors such as age, extent of surgical intervention, duration of complaints, site of tumour, histologic grade of the tumours and the Karnofsky performance status, we studied retrospectively 179 patients with histologically proven cerebral gliomas treated ... | ['Adult', 'Astrocytoma', 'Combined Modality Therapy', 'Humans', 'Prognosis', 'Retrospective Studies', 'Supratentorial Neoplasms'] | 7,927,055 | [['M01.060.116'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development. | A complete understanding of the transcriptional regulation of developmental lineages requires that all relevant factors be identified. Here, we have taken a proteomic approach to identify novel proteins associated with GATA-1, a lineage-restricted zinc finger transcription factor required for terminal erythroid and meg... | ['Amino Acid Sequence', 'Animals', 'Animals, Genetically Modified', 'Cell Differentiation', 'Cell Line', 'DNA-Binding Proteins', 'Embryo, Nonmammalian', 'Embryonic Stem Cells', 'Erythroid Cells', 'GATA1 Transcription Factor', 'Megakaryocytes', 'Mice', 'Molecular Sequence Data', 'Ploidies', 'Protein Binding', 'Rats', 'T... | 18,250,154 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G04.152'], ['A11.251.210'], ['D12.776.260'], ['A13.350', 'A16.331'], ['A11.872.700.250'], ['A11.443'], ['D12.776.260.235.500', 'D12.776.260.257.100', 'D12.776.930.216.500', 'D12.776.930.314.100'], ['A11.148.479', 'A15.378.31... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Microanatomical effects of ethanolic extract of Cola nitida on the stomach mucosa of adult Wistar rats. | The study investigated the microanatomical effects of the extracts of Cola nitida on the stomach mucosa of adult male Wistar rats. Twenty adult male wistar rats were randomly divided into four equal groups of A, B, C and D (n = 5). Animals in experimental groups B, C and D were given 600 mg/kg body weight of crude extr... | ['Animals', 'Cola', 'Ethanol', 'Gastric Mucosa', 'Male', 'Microscopy', 'Nuts', 'Plant Extracts', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Stomach Ulcer'] | 21,304,612 | [['B01.050'], ['B01.650.940.800.575.912.250.859.821.500.212'], ['D02.033.375'], ['A03.556.875.875.440', 'A10.615.550.291'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['A18.024.500.500', 'G07.203.300.700', 'J02.500.700'], ['D20.215.784.500', 'D26.667'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.67... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Access to fertility services in Canada for HIV-positive individuals and couples: a comparison between 2007 and 2014. | In the modern era of HIV care, a multitude of clinical needs have emerged; one such need is the growing sub-specialty of HIV and reproductive health. In 2007, a study surveying Canadian fertility clinics found limited access to fertility services for HIV-positive patients. Given the extensive efforts made to address th... | ['Adult', 'Ambulatory Care Facilities', 'Canada', 'Family Planning Services', 'Female', 'Fertility', 'HIV Infections', 'HIV Seropositivity', 'Health Care Surveys', 'Health Policy', 'Health Services Accessibility', 'Humans', 'Male', 'Pregnancy', 'Reproductive Techniques, Assisted'] | 28,553,759 | [['M01.060.116'], ['N02.278.035'], ['Z01.107.567.176'], ['N02.421.143.401', 'N02.421.800.249'], ['G08.686.210'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pioneering Annual Colorectal Cancer Screening and Treatment Targeting Low Income Communities in Malaysia (20102015). | The aim of this study was to assess the rate of uptake of a customised annual Colorectal Cancer Awareness, Screening and Treatment Project (CCASTP) using faecal immunohistochemical test (FIT) kits in low income communities in Malaysia. The immediate objectives were (1) to evaluate the level of adherence of CRC screenin... | ['Aged', 'Colonoscopy', 'Colorectal Neoplasms', 'Early Detection of Cancer', 'Feces', 'Female', 'Follow-Up Studies', 'Humans', 'Malaysia', 'Male', 'Middle Aged', 'Occult Blood', 'Poverty', 'Prognosis', 'Risk Factors'] | 27,509,948 | [['M01.060.116.100'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.390.500'], ['A12.459'], ['E05.318.372.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The economic origins of ultrasociality. | Ultrasociality refers to the social organization of a few species, including humans and some social insects, having a complex division of labor, city-states, and an almost exclusive dependence on agriculture for subsistence. We argue that the driving forces in the evolution of these ultrasocial societies were economic.... | ['Agriculture', 'Animals', 'Crop Production', 'Economics, Behavioral', 'Ecosystem', 'Group Processes', 'Hierarchy, Social', 'Humans', 'Insecta', 'Personal Autonomy', 'Social Behavior', 'Work'] | 25,915,060 | [['J01.040'], ['B01.050'], ['J01.040.227'], ['F04.096.628.286', 'N03.219.215'], ['G16.500.275.157', 'N06.230.124'], ['F01.829.316'], ['I01.880.853.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.131.617'], ['F02.600', 'I01.880.604.473.380.500', 'K01.752.566.479.830.650', 'N03.706.437.380.500', 'N0... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Digital image analysis in dental research applied for treatment of fissures on occlusal surfaces of premolars. | The aim of this paper was to quantitatively assess caries changes of teeth by using digital image analysis. Digital images of stained sections of crowns of teeth were acquired with a computer-assisted light microscope. In each image, spots representing the main and total demineralization of enamel were segmented to det... | ['Adolescent', 'Bicuspid', 'Dental Fissures', 'Dental Occlusion', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'In Vitro Techniques', 'Male', 'Microscopy', 'Pattern Recognition, Automated', 'Pit and Fissure Sealants', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Surface Properties', '... | 12,918,908 | [['M01.060.057'], ['A14.549.167.860.150'], ['C07.793.720.210.220'], ['E06.276', 'G10.549.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E05.481'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['L01.399.750'], ['D25.339.773', 'J01.637.05... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Microbial hazard of salted OM El-Kholoul (wedge shell Donax trunculus). | Sixty samples of salted OM El-Kholoul were collected from different localities in Giza, Alexandria and Ismailia. The samples were examined organoleptically and bacteriological examination of samples were performed for enumeration of aerobic, Enterobacteriaceae, Staph. aureus, Enterococci counts as well as isolation and... | ['Animals', 'Bacteria, Aerobic', 'Beverages', 'Citrus', 'Enterobacteriaceae', 'Mollusca', 'Shellfish', 'Sodium Chloride, Dietary', 'Vibrio parahaemolyticus'] | 9,529,997 | [['B01.050'], ['B03.120'], ['G07.203.100', 'J02.200'], ['B01.650.940.800.575.912.250.875.177'], ['B03.440.450.425', 'B03.660.250.150'], ['B01.050.500.644'], ['G07.203.300.600.875.700', 'J02.500.600.875.700'], ['D01.857.650.705', 'D01.857.875.705'], ['B03.440.450.900.859.550', 'B03.660.250.830.830.590']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Predictive value for coronary heart disease of baseline high-density and low-density lipoprotein cholesterol among Fredrickson type IIa subjects in the Helsinki Heart Study. | In the Helsinki Heart Study 2,590 subjects (63.5% of total) had a type IIa hyperlipoproteinemia at screening. Baseline low-density lipoprotein (LDL) cholesterol (mean 193 mg/dl; 5 mmol/liter) and high-density lipoprotein (HDL) cholesterol (mean 50.2 mg/dl; 1.3 mmol/liter) showed no statistical correlation (r = 0.046). ... | ['Cholesterol, HDL', 'Cholesterol, LDL', 'Coronary Disease', 'Finland', 'Gemfibrozil', 'Humans', 'Hyperlipoproteinemia Type II', 'Incidence', 'Middle Aged', 'Placebos', 'Probability', 'Random Allocation', 'Risk Factors', 'Triglycerides'] | 2,392,990 | [['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['C14.280.647.250', 'C14.907.585.250'], ['Z01.542.816.186'], ['D02.241.081.114.968.500.750', 'D02.241.081.944.509.350', 'D0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Screening for biomarkers reflecting the progression of Babesia microti infection. | BACKGROUND: Babesiosis is caused by the invasion of erythrocytes by parasites of the Babesia spp. Babesia microti is one of the primary causative agents of human babesiosis. To better understand the status of the disease, discovering key biomarkers of the different infection stages is crucial.RESULTS: This study invest... | ['Animals', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Babesia microti', 'Babesiosis', 'Biomarkers', 'Data Accuracy', 'Disease Models, Animal', 'Disease Progression', 'Enzyme-Linked Immunosorbent Assay', 'Erythrocytes', 'Female', 'Humans', 'Immunoglobulin G', 'Mice', 'Parasitemia', 'Protein Array Analysis', 'Prot... | 29,970,143 | [['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['B01.043.075.600.580.070.550'], ['C01.610.701.688.122', 'C01.610.752.075', 'C01.610.752.625.122', 'C01.920.930.182', 'C22.674.710.122'], ['D23.101'], ['E05.318.308.028', 'E05.318.370.725.250', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Salvage radiotherapy in patients with persistently detectable PSA or PSA rising from an undetectable range after radical prostatectomy gives comparable results. | PURPOSE: Salvage radiotherapy (SRT) is applied routinely in patients with a biochemical relapse after radical prostatectomy (RP). Although the detection threshold for relapse after RP has steadily been lowered, only about 30% of the SRT patients achieve a durable response. We have previously shown the association betwe... | ['Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Disease-Free Survival', 'Humans', 'Kallikreins', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prostatic Neoplasms', 'Retrospective Studies', 'Salvage Therapy', 'Treatment Outcome'] | 22,460,203 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.442', 'D08.811.277.656.95... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Gramicidin channels: a new mechanism for transmembrane transfer of ions (from high resolution x-ray structural studies of the antibiotic)]. | The crystal structure of the membrane-active antibiotic-cyclopeptide gramicidin S complex with urea was determined by the X-ray structure analysis. The gramicidin S molecule possesses an antiparallel beta-structure, its slightly twisted 30-membered cycle has a roughly rectangular form about 4.8 x 13.6 A in size, with t... | ['Amino Acid Sequence', 'Biological Transport', 'Cell Membrane', 'Gramicidin', 'Ion Channels', 'Molecular Sequence Data', 'Protein Conformation', 'X-Ray Diffraction'] | 1,381,919 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G03.143'], ['A11.284.149'], ['D04.345.566.850.300', 'D12.644.641.850.300', 'D12.776.543.695.221'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['L01.453.245.667'], ['G02.111.570.820.709'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Determination of sucrose in equine serum using liquid chromatography-mass spectrometry (LC/MS). | Mucosal integrity may be objectively assessed by determination of the absorption of exogenous substances such as sucrose. Gas chromatography-mass spectrometry (GC/MS) and liquid chromatography-mass spectrometry (LC/MS) have been reported for the accurate quantification of low concentrations of sucrose in serum. LC/MS o... | ['Animals', 'Chromatography, Liquid', 'Fructose', 'Glucose', 'Horses', 'Ions', 'Mass Spectrometry', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Sucrose'] | 22,024,392 | [['B01.050'], ['E05.196.181.400'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.984.235.472'], ['D01.248.497'], ['E05.196.566'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Postural orthostatic tachycardia syndrome: a rare complication following electrical injury. | We report on two previously healthy patients who developed severe form of postural orthostatic tachycardia syndrome (POTS) following an electric injury. Both the patients developed symptoms of orthostatic intolerance in the form of dizziness, fatigue, lightheadedness, and palpitations, weeks to months after electrical ... | ['Adult', 'Diagnosis, Differential', 'Electric Injuries', 'Electrocardiography', 'Humans', 'Male', 'Middle Aged', 'Postural Orthostatic Tachycardia Syndrome', 'Rare Diseases'] | 20,015,131 | [['M01.060.116'], ['E01.171'], ['C26.324'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.177.575.600.625'], ['C23.550.291.906']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Re-affirmation of a Preliminary Live with Love Conceptual Framework for cancer couple dyads: A couple-based complex intervention study. | PURPOSE: The relational dynamics of couples may be under great strain due to the diagnosis and treatment of cancer. A complex "Caring for Couples Coping with Cancer" (4Cs) intervention program, guided by a Preliminary Live with Love Conceptual Framework (P-LLCF) for Cancer Couple Dyads, was developed to support couples... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Caregivers', 'China', 'Female', 'Humans', 'Interpersonal Relations', 'Love', 'Male', 'Middle Aged', 'Neoplasms', 'Quality of Life', 'Spouses'] | 26,447,085 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.470.734'], ['M01.060.116.630'], ['C04'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['F01.829.263.500.660', 'I01... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Roles of RNase E, RNase II and PNPase in the degradation of the rpsO transcripts of Escherichia coli: stabilizing function of RNase II and evidence for efficient degradation in an ams pnp rnb mutant. | The Escherichia coli rpsO gene gives rise to different mRNA species resulting either from termination of transcription or from processing of primary transcripts by RNase E and RNase III. The main degradation pathway of these transcripts involves a rate-limiting RNase E cleavage downstream of the structural gene which r... | ['Base Sequence', 'DNA Nucleotidyltransferases', 'Endoribonucleases', 'Escherichia coli', 'Exoribonucleases', 'Integrases', 'Models, Genetic', 'Molecular Sequence Data', 'Mutation', 'Nucleic Acid Conformation', 'Polyribonucleotide Nucleotidyltransferase', 'Protein Denaturation', 'RNA Precursors', 'RNA Processing, Post-... | 7,519,147 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.696.445.308'], ['D08.811.277.352.355.350', 'D08.811.277.352.700.350'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.352.365.300', 'D08.811.277.352.700.375'], ['D08.811.739.500'], ['E05.599.395.397'], ['L01.453.245.667'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Providing pastoral care services in a clinical setting to veterans at-risk of suicide. | The value of enhanced spiritual wellbeing has largely been overlooked as part of suicide prevention efforts in Veterans. The aim of this qualitative study is to examine the clinical pastoral care services provided by VA Chaplains to Veterans at-risk of suicide. This study was conducted using in-depth interviews with fi... | ['Clergy', 'Humans', 'New York', 'Pastoral Care', 'Primary Health Care', 'Qualitative Research', 'Spirituality', 'Suicide', 'Veterans'] | 23,471,771 | [['M01.526.799.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.437', 'Z01.107.567.875.350.530', 'Z01.107.567.875.500.530'], ['F02.784.176.560', 'F02.880.410'], ['N04.590.233.727'], ['H01.770.644.241.850'], ['F02.880.705', 'K01.844.664.500'], ['F01.145.126.980.875', 'I01.880.735.856'], ['M0... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Prognostic risk assessment in primary breast cancer by behavioral and immunological parameters. | Although findings from recent animal studies suggest that behavioral factors such as "helplessness" play a role in cancer progression, very few such studies with humans have been carried out. The study investigated the predictive power of an immunologic effector cell, the natural killer (NK) cell, as well as selected p... | ['Adult', 'Aged', 'Breast Neoplasms', 'Female', 'Humans', 'Killer Cells, Natural', 'Lymph Nodes', 'Middle Aged', 'Prognosis', 'Random Allocation', 'Risk'] | 4,018,006 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['A10.549.400', 'A15.382.520.604.412'], ['M01.060.116.630'], ['E01.789'], ['E05.318.370.700', 'E05.581.500.80... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Recurrent lower gastrointestinal bleeding due to a gastrointestinal stromal tumor (GIST) of the small intestine]. | Gastrointestinal bleeding is a common cause of hospitalisation. In most patients, the origin and location of bleeding can be established in routine endoscopic and radiological examinations. The undiagnosed cases of so-called gastrointestinal bleeding of unknown origin require more sophisticated diagnostic methods. We p... | ['Adult', 'Gastrointestinal Hemorrhage', 'Gastrointestinal Stromal Tumors', 'Humans', 'Jejunal Neoplasms', 'Male', 'Recurrence'] | 16,886,571 | [['M01.060.116'], ['C06.405.227', 'C23.550.414.788'], ['C04.557.450.565.370', 'C06.301.371.308', 'C06.405.249.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411.523', 'C06.301.371.411.523', 'C06.405.249.411.523', 'C06.405.469.491.523', 'C06.405.469.600.523'], ['C23.550.291.937']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Declining HIV incidence among patients attending sexually transmitted infection clinics in Pune, India. | OBJECTIVE: A recent report suggesting declining HIV transmission rates in southern India has been based on HIV seroprevalence data to estimate HIV incidence. We analyzed HIV incidence rates among 3 cohorts (male, female non-sex worker, female sex worker [FSW]) presenting to sexually transmitted infection (STI) clinics ... | ['Adult', 'Cohort Studies', 'Condoms', 'Female', 'HIV Infections', 'HIV-1', 'HIV-2', 'Humans', 'Incidence', 'India', 'Male', 'Prospective Studies', 'Regression Analysis', 'Risk Factors', 'Safe Sex', 'Sex Work'] | 17,558,335 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E07.190.270.150'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B04.820.650.589.650.350.410'], ['B01.050.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Further isolation and characterization of grammistins from the skin secretion of the soapfish Grammistes sexlineatus. | Soapfishes contain peptide toxins (grammistins) in the skin secretion. Two grammistins (Gs 1 and Gs 2) and six grammistins (Pp 1, Pp 2a, Pp 2b, Pp 3, Pp 4a and Pp 4b) have already been isolated from Grammistes sexlineatus and Pogonoperca punctata, respectively. In this study, five grammistins (Gs A-E), together with gr... | ['Amino Acid Sequence', 'Animals', 'Anti-Bacterial Agents', 'Cell Membrane', 'Chromatography, Gel', 'Chromatography, High Pressure Liquid', 'Fish Venoms', 'Fluoresceins', 'Gram-Positive Bacteria', 'Hemolysis', 'Liposomes', 'Molecular Sequence Data', 'Perciformes', 'Sequence Analysis, Protein', 'Skin'] | 15,777,955 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.122.085'], ['A11.284.149'], ['E05.196.181.400.250'], ['E05.196.181.400.300'], ['D20.888.370', 'D23.946.580.370', 'D23.946.833.370'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['B03.510'], ['C23.550.403', 'G12.122.545'], ['D25.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
A satisfaction survey of opioid-dependent patients with methadone maintenance treatment. | The aim of this study was to examine opioid-dependent patients' satisfaction with the methadone maintenance treatment (MMT) program in Malaysia and identify predictors of satisfaction. We used an interviewer-administered questionnaire developed and validated by Rankin Court, New South Wales, Australia. Of 502 patients ... | ['Adult', 'Delivery of Health Care', 'Female', 'Humans', 'Male', 'Methadone', 'Middle Aged', 'New South Wales', 'Opiate Substitution Treatment', 'Opioid-Related Disorders', 'Patient Satisfaction', 'Socioeconomic Factors', 'Substance Abuse Treatment Centers', 'Surveys and Questionnaires'] | 25,616,750 | [['M01.060.116'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.522.675'], ['M01.060.116.630'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['E02.319.620'], ['C25.775.643.500', 'F03.900.647.500'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Hearing disability in people aged 50-65: effectiveness and acceptability of rehabilitative intervention. | OBJECTIVE: To determine the best means of detecting hearing disability in subjects aged 50-65 and whether rehabilitative intervention is acceptable in this age group.DESIGN: Questionnaire survey of patients on general practice age-sex registers. Two types of questionnaire were used, one being based on the closed set ap... | ['Aged', 'Correction of Hearing Impairment', 'Female', 'Hearing Aids', 'Hearing Disorders', 'Humans', 'Male', 'Middle Aged', 'Patient Acceptance of Health Care', 'Pilot Projects', 'Prevalence', 'Surveys and Questionnaires', 'Wales'] | 2,107,929 | [['M01.060.116.100'], ['E02.760.169.063.500.200', 'E02.831.200', 'H02.403.680.600.500', 'N02.421.784.377'], ['E07.305.906.500', 'E07.814.458'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500', 'F01.145.488.887.500', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Learning to assist smokers through encounters with standardized patients: An innovative training for physicians in an Eastern European country. | OBJECTIVES: A lack of physician training is a major obstacle for effective tobacco dependence treatment. This study assessed the feasibility of an active learning training program and its effects on smoking cessation counselling skills of medical residents in Armenia, an Eastern European country with high smoking preva... | ['Adult', 'Armenia', 'Counseling', 'Education, Medical, Continuing', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Educational', 'Patient Simulation', 'Physicians', 'Problem-Based Learning', 'Program Evaluation', 'Smokers', 'Smoking Cessation', 'Surveys and Questionnaires', 'Tobacco Use Dis... | 31,557,211 | [['M01.060.116'], ['Z01.542.900.099', 'Z01.542.931.099', 'Z01.586.035.150', 'Z01.586.950.099'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['I02.358.212.350', 'I02.358.399.250'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Predictive factors associated with three years of response to HbA1c goals with exenatide QW or insulin glargine: Post-hoc analysis of the DURATION-3 study. | This post-hoc analysis of the DURATION-3 study aimed to identify factors associated with sustained glycaemic response with exenatide once weekly (QW) or insulin glargine (IG) among patients with type 2 diabetes. Response was defined as achieving treatment target of HbA1c <7.0% (<53 mmol/mol) at Week 26; sustained respo... | ['Aged', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Drug Administration Schedule', 'Exenatide', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemic Agents', 'Insulin Glargine', 'Logistic Models', 'Male', 'Middle Aged', 'Prognosis', 'Treatment Outcome'] | 30,520,252 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.319.283'], ['D12.644.187', 'D20.888.300', 'D23.946.833.300'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of aging on the functional outcome of coloanal anastomosis with colonic J-pouch. | BACKGROUND: Many low rectal cancers can be treated radically by proctectomy with total mesorectal excision followed by colonic J-pouch anal anastomosis (CPAA). In elderly patients, the fear of poor function might reduce indications for CPAA in favor of abdomino-perineal excision with end stoma.METHODS: Among 198 patien... | ['Adenocarcinoma', 'Adult', 'Age Factors', 'Aged', 'Anal Canal', 'Anastomosis, Surgical', 'Colon', 'Defecation', 'Fecal Incontinence', 'Humans', 'Middle Aged', 'Postoperative Complications', 'Proctocolectomy, Restorative', 'Rectal Neoplasms', 'Treatment Outcome'] | 9,560,121 | [['C04.557.470.200.025'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['E04.035'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['G10.261.165'], ['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reducing the impact of PCR-mediated recombination in molecular evolution and environmental studies using a new-generation high-fidelity DNA polymerase. | PCR-mediated recombination can greatly impact estimates of diversity, both in environmental studies and in analyses of gene family evolution. Here we measure chimera (PCR-mediated recombinant) formation by analyzing a mixture of eight partial actin sequences isolated from the amoeba Arcella hemisphaerica amplified unde... | ['Actins', 'Amoeba', 'Animals', 'Base Sequence', 'Chimera', 'DNA, Recombinant', 'DNA-Directed DNA Polymerase', 'Evolution, Molecular', 'Genetic Variation', 'Haplotypes', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Recombination, Genetic', 'Sequence Homology, Nucleic Acid', 'Temperature', 'Templates, Geneti... | 19,852,769 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.046.500.100.700.089'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B05.200'], ['D13.444.308.460'], ['D08.811.913.696.445.308.300'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['G05.380.360'], ['L01.453.245.667'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Renal sonography in the intensive care unit: when is it necessary? | OBJECTIVE: To evaluate the efficacy of renal sonography performed in intensive care units on patients with the diagnosis of acute or acute-on-chronic renal failure.METHODS: We reviewed all renal sonograms performed in our institution during 1 year on critically ill patients for evaluation of renal failure. Renal failur... | ['Acute Kidney Injury', 'Adult', 'Aged', 'Aged, 80 and over', 'Blood Urea Nitrogen', 'Costs and Cost Analysis', 'Creatinine', 'Critical Illness', 'Female', 'Health Services Misuse', 'Humans', 'Hydronephrosis', 'Intensive Care Units', 'Kidney', 'Male', 'Middle Aged', 'Ultrasonography', 'United States'] | 12,008,814 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['N03.219.151'], ['D03.383.129.308.207'], ['C23.550.291.625'], ['N02.421.380', 'N05.300.150.395'], ['B01.050.150.900.649.313.988.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Characterization of tiger-tail banding and hair shaft abnormalities in trichothiodystrophy. | BACKGROUND: Tiger tail banding under polarizing light microscopy and hair shaft abnormalities are associated with trichothiodystrophy (TTD), a rare disorder with a wide spectrum of clinical presentations.OBJECTIVE: To characterize the frequency, specificity, and extent of tiger tail banding and hair shaft abnormalities... | ['Cystine', 'DNA Repair', 'Darier Disease', 'Ectodermal Dysplasia', 'Hair', 'Hair Diseases', 'Humans', 'Hyperkeratosis, Epidermolytic', 'Ichthyosis', 'Microscopy, Polarization', 'Photosensitivity Disorders', 'Sensitivity and Specificity', 'Sulfur', 'Syndrome', 'Xeroderma Pigmentosum'] | 15,692,466 | [['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.230.369'], ['G02.111.222', 'G05.219'], ['C16.320.850.190', 'C17.800.428.275', 'C17.800.827.190'], ['C16.131.077.350', 'C16.131.831.350', 'C16.320.850.250', 'C17.80... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Identification of couple-stress moduli of vertebral trabecular bone based on the 3D internal architectures. | The purpose of this paper is to develop a homogeneous, orthotropic couple-stress continuum model as a substitute of the 3D periodic heterogeneous cellular solid model of vertebral trabecular bone. Vertebral trabecular bone is modeled as a porous material with an idealized periodic structure made of 3D open cubic cells,... | ['Biomechanical Phenomena', 'Bone Marrow', 'Finite Element Analysis', 'Materials Testing', 'Models, Biological', 'Spine', 'Stress, Mechanical'] | 26,232,945 | [['G01.154.090', 'G01.374.089'], ['A15.382.216'], ['E05.355'], ['E05.570'], ['E05.599.395'], ['A02.835.232.834'], ['G01.374.835']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemoprophylaxis for venous thromboembolism in otolaryngology. | IMPORTANCE: Venous thromboembolism (VTE) causes significant morbidity and mortality in surgical patients. Despite strong evidence that thromboprophylaxis reduces the incidence VTE, guidelines for prophylaxis in otolaryngology are not well established. Key to the development of VTE prophylaxis recommendations are effect... | ['Anticoagulants', 'Enoxaparin', 'Fondaparinux', 'Free Tissue Flaps', 'Hemorrhage', 'Heparin', 'Humans', 'Incidence', 'Otolaryngology', 'Otorhinolaryngologic Surgical Procedures', 'Polysaccharides', 'Retrospective Studies', 'Risk Assessment', 'Venous Thromboembolism'] | 25,275,427 | [['D27.505.954.502.119'], ['D09.698.373.400.300.200'], ['D09.698.629.429'], ['A10.850.710.500', 'E07.862.710.500'], ['C23.550.414'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['H... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
When music is salty: The crossmodal associations between sound and taste. | Here we investigate associations between complex auditory and complex taste stimuli. A novel piece of music was composed and recorded in four different styles of musical articulation to reflect the four basic tastes groups (sweet, sour, salty, bitter). In Experiment 1, participants performed above chance at pairing the... | ['Female', 'Humans', 'Male', 'Music', 'Pattern Recognition, Physiological', 'Pleasure', 'Sound', 'Taste', 'Taste Perception', 'Young Adult'] | 28,355,227 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.602'], ['F02.463.593.524'], ['F01.470.867', 'F02.830.816.492'], ['G01.750.770.776'], ['F02.830.816.724', 'G11.561.790.724'], ['F02.463.593.817'], ['M01.060.116.815']] | ['Organisms [B]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Continuous somatosensory evoked potential monitoring in the NICU. | Monitoring of somatosensory evoked potentials (SSEP) of head-injured patients is a frequent and interesting topic in the neuroscience nursing arena. Often, however, nursing involvement in the recording of somatosensory evoked potentials has been limited to observing the once a week procedure and documenting patient out... | ['Brain Injuries', 'Evoked Potentials, Somatosensory', 'Humans', 'Intensive Care Units', 'Monitoring, Physiologic'] | 3,849,566 | [['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E01.370.520']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Importance of mitochondrial dynamin-related protein 1 in hypothalamic glucose sensitivity in rats. | AIMS: Hypothalamic mitochondrial reactive oxygen species (mROS)-mediated signaling has been recently shown to be involved in the regulation of energy homeostasis. However, the upstream signals that control this mechanism have not yet been determined. Here, we hypothesize that glucose-induced mitochondrial fission plays... | ['Animals', 'Appetite Regulation', 'Arcuate Nucleus of Hypothalamus', 'Dynamins', 'Energy-Generating Resources', 'Gene Knockdown Techniques', 'Glucose', 'Insulin', 'Insulin Secretion', 'Insulin-Secreting Cells', 'Male', 'Mitochondria', 'Mitochondrial Membranes', 'Oxygen Consumption', 'Protein Transport', 'RNA Interfere... | 22,229,526 | [['B01.050'], ['G07.203.650.170', 'G07.203.650.390.070.290', 'G10.261.390.070.290'], ['A08.186.211.180.497.352.081', 'A08.186.211.200.317.357.352.081'], ['D08.811.277.040.330.200', 'D12.776.220.600.450.200', 'D12.776.543.990.400'], ['N06.230.132'], ['E05.393.335.500'], ['D09.947.875.359.448'], ['D06.472.699.587.200.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Exploring the effects of seasonality and chemical pollution on the hepatopancreas transcriptome of the Manila clam. | The assessment of marine environmental health is a complex but fundamental task both for ecosystem conservation and food safety related to the human consumption of marine products. Manila clams inhabiting the Venice Lagoon constitute an excellent case study for evaluating the effects of complex mixtures of industrial a... | ['Animals', 'Bivalvia', 'Ecosystem', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Hazardous Substances', 'Hepatopancreas', 'Humans', 'Polychlorinated Biphenyls', 'Seasons', 'Water Pollution, Chemical'] | 23,480,613 | [['B01.050'], ['B01.050.500.644.080'], ['G16.500.275.157', 'N06.230.124'], ['E05.393.332'], ['G05.308'], ['D27.888.426'], ['A13.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluating fetal head dimension changes during labor using open magnetic resonance imaging. | AIM: Fetal skull molding is important for the adaptation of the head to the birth canal during vaginal delivery. Importantly, the fetal head must rotate around the maternal symphysis pubis. The goals of this analysis were to observe a human birth in real-time using an open magnetic resonance imaging (MRI) scanner and d... | ['Biomechanical Phenomena', 'Computer Systems', 'Female', 'Fetus', 'Head', 'Humans', 'Infant, Newborn', 'Labor Presentation', 'Labor Stage, Second', 'Magnetic Resonance Imaging', 'Male', 'Pregnancy', 'Young Adult'] | 27,219,097 | [['G01.154.090', 'G01.374.089'], ['L01.224.230'], ['A16.378'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.520', 'G08.686.784.769.326.520'], ['G08.686.784.769.326.500.090'], ['E01.370.350.825.500'], ['G08.686.784.769'], ['M01.060.116.815']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Patient perceptions on mesh use in hernia repair: A prospective, questionnaire-based study. | BACKGROUND: There has been increasing media coverage regarding the controversy of using mesh in various operations. At this time, there are no published studies evaluating the potential influence of this controversy on patients' perceptions. Therefore, our study aimed to assess patient perceptions of hernia repair surg... | ['Aged', 'Female', 'Herniorrhaphy', 'Humans', 'Male', 'Middle Aged', 'Perception', 'Prospective Studies', 'Surgical Mesh', 'Surveys and Questionnaires'] | 32,061,401 | [['M01.060.116.100'], ['E04.680.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E07.858.708'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inside the courtroom: An analysis of malpractice litigation in gallbladder surgery. | BACKGROUND: Cholecystectomy is one of the most commonly performed operations in the United States, yet it still carries up to a 6% risk of major morbidity. Lawsuits are a major source of emotional, financial, and personal stress for surgeons. We sought to characterize malpractice claims associated with gallbladder surg... | ['Adult', 'Cholecystectomy', 'Databases, Factual', 'Female', 'Humans', 'Male', 'Malpractice', 'Medical Errors', 'Middle Aged'] | 32,439,206 | [['M01.060.116'], ['E04.210.120.172'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583.524', 'N03.706.535.606'], ['N02.421.450'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Exploring the repetition bias in voluntary task switching. | In the voluntary task-switching paradigm, participants are required to randomly select tasks. We reasoned that the consistent finding of a repetition bias (i.e., participants repeat tasks more often than expected by chance) reflects reasonable adaptive task selection behavior to balance the goal of random task selectio... | ['Adolescent', 'Adult', 'Choice Behavior', 'Decision Making', 'Female', 'Humans', 'Individuality', 'Male', 'Multitasking Behavior', 'Psychomotor Performance', 'Reaction Time', 'Task Performance and Analysis', 'Young Adult'] | 28,871,331 | [['M01.060.057'], ['M01.060.116'], ['F02.463.785.373.346'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F01.145.666'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Resilience criteria and factors associated with resilience in sexually abused girls. | Alternative measures of resilience and correlates of resilience were examined in a sample of 43 sexually abused girls who were assessed using a self-administered interview at the time of intake for psychotherapy. Results indicated relatively high levels of disagreement as to which girls were resilient using maintenance... | ['Adaptation, Psychological', 'Adolescent', 'Child', 'Child Abuse, Sexual', 'Female', 'Humans', 'Parent-Child Relations', 'Personality Assessment', 'Personality Development', 'Psychotherapy', 'Social Support', 'Stress, Psychological'] | 8,528,822 | [['F01.058'], ['M01.060.057'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290'], ['F04.513'], ['F01.752.747'], ['F04.754'], ['I01.880.853.500.600'], ['F01.145.126.990', 'F02.830.900']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
EBV-associated Kaposi's sarcoma in a pediatric renal transplant recipient. | A 7-year-old boy had undergone kidney transplantation for chronic renal failure secondary to bilateral renal hypoplasia. He developed acute and chronic rejection and received immunosuppressive therapy. A year later he died with EBV-associated hemophagocytic syndrome. The main pathologic findings disclosed visceral (lun... | ['Child', 'Fatal Outcome', 'Herpesviridae Infections', 'Herpesvirus 4, Human', 'Histiocytosis, Non-Langerhans-Cell', 'Humans', 'Immunosuppression', 'Kidney Transplantation', 'Lung Neoplasms', 'Lymph Nodes', 'Male', 'Sarcoma, Kaposi', 'Stomach Neoplasms', 'Tumor Virus Infections'] | 7,808,984 | [['M01.060.406'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C01.925.256.466'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['C15.604.250.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rhodococcus equi and Nocardia brasiliensis infection of the brain and liver in a patient with acute nonlymphoblastic leukemia. | Resolution of neutropenia is usually followed by resolution of fever in patients with febrile neutropenia. However, in some cases fever continues even when the patient is no longer neutropenic. Described here is a case of acute myeloblastic leukemia complicated by brain abscess, pulmonary nodules, and hepatic lesions. ... | ['Actinomycetales Infections', 'Adult', 'Brain Abscess', 'Female', 'Humans', 'Leukemia, Myeloid, Acute', 'Liver Diseases', 'Nocardia', 'Nocardia Infections', 'Opportunistic Infections', 'Rhodococcus equi'] | 9,865,991 | [['C01.150.252.410.040'], ['M01.060.116'], ['C01.207.090', 'C01.830.025.160', 'C10.228.140.116', 'C10.228.228.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['C06.552'], ['B03.510.024.981.550'], ['C01.150.252.410.040.692'], ['C01.597', 'C01.610.684', 'C01.925.597'], ['B03.510.024.981.7... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tripartite containing motif 32 modulates proliferation of human neural precursor cells in HIV-1 neurodegeneration. | In addition to glial cells, HIV-1 infection occurs in multipotent human neural precursor cells (hNPCs) and induces quiescence in NPCs. HIV-1 infection of the brain alters hNPC stemness, leading to perturbed endogenous neurorestoration of the CNS following brain damage by HIV-1, compounding the severity of dementia in a... | ['Adult', 'Cell Proliferation', 'HIV Infections', 'HIV-1', 'Humans', 'Immunohistochemistry', 'MicroRNAs', 'Neural Stem Cells', 'Transcription Factors', 'Tripartite Motif Proteins', 'Ubiquitin-Protein Ligases', 'tat Gene Products, Human Immunodeficiency Virus'] | 26,586,575 | [['M01.060.116'], ['G04.161.750', 'G07.345.249.410.750'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter. | Intracellular calcium levels can have profound effects on muscle biology via alterations in gene expression. In particular, intracellular calcium levels increase during muscle activation and are thought to underlie fast-to-slow shifts in muscle gene expression. In the present work, we determined that increased intracel... | ['Animals', 'Binding Sites', 'Calcimycin', 'Calcineurin', 'Calcineurin Inhibitors', 'Calcium', 'Calcium Signaling', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cell Line', 'DNA-Binding Proteins', 'Enzyme Inhibitors', 'Genes, Reporter', 'Humans', 'Ionophores', 'MAP Kinase Signaling System', 'Mice', 'Mitogen-Activat... | 12,235,157 | [['B01.050'], ['G02.111.570.120'], ['D03.633.100.221.173'], ['D08.811.277.352.650.625.150', 'D12.644.360.087', 'D12.776.476.087'], ['D27.505.519.389.174'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D08.811.913.696.620.682.700.125', 'D12.644.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aqueous humour levels of cytokines are correlated to vitreous levels and severity of macular oedema in branch retinal vein occlusion. | AIM: To investigate whether the aqueous levels of vascular endothelial growth factor (VEGF) and interleukin-6 (IL-6) are correlated to the vitreous levels of these substances and to the severity of macular oedema in branch retinal vein occlusion (BRVO).METHODS: Aqueous and vitreous samples were obtained during cataract... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aqueous Humor', 'Biomarkers', 'Cytokines', 'Female', 'Humans', 'Interleukin-6', 'Macular Edema', 'Male', 'Middle Aged', 'Retinal Vein Occlusion', 'Statistics as Topic', 'Vascular Endothelial Growth Factor A', 'Vitreous Body'] | 16,826,241 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A09.371.060.067.070', 'A12.207.270.040'], ['D23.101'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['C11.768.585.43... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of exon-deleted progesterone receptor mRNAs in human uterine endometrial cancers. | We demonstrated the expression of various exon-deleted progesterone receptor (PR) variant mRNAs in human uterine endometrial cancers using the reverse transcription-polymerase chain reaction-DNA sequencing analyses. In addition to PR wild-type mRNA, exon 4-deleted, exon 6-deleted, exon 3,4-deleted, exon 5,6-deleted, ex... | ['Endometrial Neoplasms', 'Exons', 'Female', 'Gene Deletion', 'Humans', 'Middle Aged', 'RNA', 'RNA, Messenger', 'RNA, Neoplasm', 'Receptors, Progesterone', 'Reverse Transcriptase Polymerase Chain Reaction'] | 10,644,942 | [['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['G05.360.340.024.340.137.232'], ['G05.365.590.762.320', 'G05.558.800.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D13.444.735'], ['D13.444.735.544'], ['D13.444.735.615'], ['D12.776.826.750.765'], ['E05... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A twelve-analyzer detector system for high-resolution powder diffraction. | A dedicated high-resolution high-throughput X-ray powder diffraction beamline has been constructed at the Advanced Photon Source (APS). In order to achieve the goals of both high resolution and high throughput in a powder instrument, a multi-analyzer detector system is required. The design and performance of the 12-ana... | ['Equipment Design', 'Powder Diffraction', 'Synchrotrons', 'X-Ray Diffraction'] | 18,728,312 | [['E05.320'], ['E05.196.309.711'], ['E07.710.680.700'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Familial distal arthrogryposis type I. | Distal arthrogryposis type I is defined by congenital joint contractures of hands and feet and is inherited in an autosomal dominant fashion. The hands are most frequently involved than the feet, 98% and 88% of the cases, respectively. The authors report a family with five patients affected over four generations. This ... | ['Arthrogryposis', 'Child', 'Foot Deformities, Congenital', 'Genes, Dominant', 'Hand Deformities, Congenital', 'Humans', 'Male', 'Pedigree', 'Radiography'] | 8,766,137 | [['C05.550.150', 'C05.651.102', 'C05.660.077', 'C16.131.621.077'], ['M01.060.406'], ['C05.330.495', 'C05.660.585.512.380', 'C16.131.621.585.512.500'], ['G05.360.340.024.340.240', 'G05.420.320'], ['C05.390.408', 'C05.660.585.988.425', 'C16.131.621.585.988.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Superabsorbent crosslinked carboxymethyl cellulose-PEG hydrogels for potential wound dressing applications. | This study focused on the synthesis and comprehensive characterization of environmentally friendly hydrogel membranes based on carboxymethyl cellulose (CMC) for wound dressing and skin repair substitutes. These new CMC hydrogels were prepared with two degrees of functionalization (DS=0.77 and 1.22) and chemically cross... | ['Bandages', 'Biocompatible Materials', 'Carboxymethylcellulose Sodium', 'Cross-Linking Reagents', 'HEK293 Cells', 'Humans', 'Hydrogels', 'Polyethylene Glycols', 'Wound Healing'] | 28,851,645 | [['E07.101'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D09.698.365.180.663.329'], ['D27.720.470.410.210'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.280.320.375', 'D26.255.165.320.375'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Subdural pressure measurement during posterior fossa surgery. Correlation studies of brain swelling/herniation after dural incision with measurement of subdural pressure and tactile estimation of dural tension. | Thirty-two patients with posterior fossa tumours or arteriovenous malformations were subjected to elective craniotomy in the prone position. The intracranial pressure (ICP) was measured by a subdural approach in the open area of the exposed dura. Estimation of dural tension before dural incision and the degree of brain... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Cranial Fossa, Posterior', 'Craniotomy', 'Encephalocele', 'Female', 'Humans', 'Intracranial Arteriovenous Malformations', 'Intracranial Pressure', 'Male', 'Middle Aged', 'Skull Neoplasms'] | 10,627,773 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['A01.456.830.200', 'A02.835.232.781.750.400'], ['E04.525.190'], ['C10.500.680.488', 'C16.131.666.680.488', 'C23.300.707.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.520', 'C10.500.190.500', 'C14.2... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunocytochemical localization and ontogenic development of alpha-melanocyte-stimulating hormone (alpha-MSH) in the brain of a pleuronectiform fish, barfin flounder. | Alpha-melanocyte-stimulating hormone (alpha-MSH) is a pituitary hormone derived by post-translational processing from proopiomelanocortin and is involved in background adaptation in teleost fish. It has also been reported to suppress food intake in mammals. Here, we examined the immunocytochemical localization of alpha... | ['Animals', 'Brain', 'Flounder', 'Hypothalamic Hormones', 'Hypothalamus', 'Immunohistochemistry', 'Melanins', 'Mesencephalon', 'Neurons', 'Pituitary Gland', 'Pituitary Hormones', 'Telencephalon', 'alpha-MSH'] | 15,726,422 | [['B01.050'], ['A08.186.211'], ['B01.050.150.900.493.418.438'], ['D06.472.699.327', 'D12.644.400.400', 'D12.644.548.365', 'D12.776.631.650.405'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of GABA(A) receptors in the accessory olfactory bulb does not prevent the formation of an olfactory memory in mice. | When female mice are mated, they form a memory to the pheromonal signal of their male partner. The neural mechanisms underlying this memory involve changes at the reciprocal dendrodendritic synapses between glutamatergic mitral cells and gamma-aminobutyric acid (GABA)-ergic granule cells in the accessory olfactory bulb... | ['Animals', 'Female', 'GABA Agonists', 'Male', 'Memory', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred CBA', 'Muscimol', 'Olfactory Bulb', 'Pregnancy', 'Receptors, GABA-A', 'Sex Attractants'] | 11,503,910 | [['B01.050'], ['D27.505.519.625.240.200', 'D27.505.696.577.240.200'], ['F02.463.425.540'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.050.199.520.520.440', 'B01.050.150.900.649.313.992.635.505.500.400.440'], ['D03.383.129.46... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tuning mitochondrial structure and function to criticality by fluctuation-driven mechanotransduction. | Cells in vascular walls are exposed to blood pressure variability (BPV)-induced cycle-by-cycle fluctuations in mechanical forces which vary considerably with pathology. For example, BPV is elevated in hypertension but reduced under anesthesia. We hypothesized that the extent of mechanical fluctuations applied to vascul... | ['Adenosine Triphosphate', 'Animals', 'Cattle', 'Cells, Cultured', 'Mechanotransduction, Cellular', 'Mitochondria', 'Mitochondrial Proteins', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'Oxidation-Reduction', 'Oxidative Stress', 'Reactive Oxygen Species'] | 31,941,960 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['G01.154.090.500', 'G02.111.820.580', 'G04.835.580'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D12.776.575'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rastelli type repair using Freestyle valved conduit for a 69-year-old woman with tetralogy of Fallot. | A 69-year-old woman visited our hospital with general fatigue and shortness of breath on effort as the chief complaints. She was diagnosed as having tetralogy of Fallot, using cardiac ultrasonography. The cardiac catheterization findings showed that right venticular hypertension was at 114/5 mmHg, which was parallel to... | ['Aged', 'Blood Vessel Prosthesis', 'Female', 'Humans', 'Prosthesis Design', 'Tetralogy of Fallot'] | 12,691,122 | [['M01.060.116.100'], ['E07.695.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.320.550', 'E07.695.680'], ['C14.240.400.849', 'C14.280.400.849', 'C16.131.240.400.849']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis. | UNLABELLED: To address the controversy of whether TNFalpha can compensate for RANKL in osteoclastogenesis in vivo, we used a TNFalpha-induced animal model of inflammatory arthritis and blocked RANKL/RANK signaling. TNFalpha increased osteoclast precursors available for RANK-dependent osteoclastogenesis. RANK signaling ... | ['Animals', 'Arthritis, Experimental', 'CD11b Antigen', 'Carrier Proteins', 'Cell Separation', 'Enzyme-Linked Immunosorbent Assay', 'Flow Cytometry', 'Membrane Glycoproteins', 'Mice', 'Mice, Transgenic', 'Osteoclasts', 'RANK Ligand', 'Receptor Activator of Nuclear Factor-kappa B', 'Signal Transduction', 'Tumor Necrosis... | 14,969,390 | [['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['D12.776.395.550.200.074.750', 'D12.776.543.550.200.093.750', 'D12.776.543.750.705.408.100.150', 'D12.776.543.750.705.833.062', 'D23.050.301.350.074.049'], ['D12.776.157'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.478.566.350.170', 'E05.478.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of macromolecular methylations in promastigotes of Leishmania donovani and impact of sinefungin. | Sinefungin, an antifungal and antiparasitic nucleoside antibiotic, is a very potent antileishmanial agent both in vitro and in vivo. This molecule, structurally related to S-adenosylmethionine, is a good competitive inhibitor of methyltransferases in vitro. The aim of this report is to analyze the impact of sinefungin ... | ['Adenosine', 'Animals', 'Leishmania donovani', 'Macromolecular Substances', 'Methylation', 'Protein Methyltransferases', 'Protozoan Proteins', 'S-Adenosylmethionine', 'Subcellular Fractions'] | 8,401,471 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['B01.268.475.868.488.230'], ['D05'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D08.811.913.555.500.800'], ['D12.776.820'], ['D02.886.030.676.180', 'D03.633.100.759.590.138.264', 'D12.125.166.676.180', 'D13.570.583.138.264',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
General practice critical incident reviews of patient suicides: benefits, barriers, costs, and family participation. | AIM: To explore the feasibility of holding critical incident reviews (CIRs) after patient suicides in general practice and their ability to change practice.METHODS: Thirteen practices were invited to conduct a facilitated CIR on 18 current patient suicides. Next of kin views were sought. All staff attending a CIR were ... | ['Family', 'Family Practice', 'Humans', 'Patients', 'Peer Review, Health Care', 'Suicide'] | 15,691,999 | [['F01.829.263', 'I01.880.853.150'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643'], ['F01.829.316.549.690', 'I01.880.604.640.690', 'N03.706.700.690', 'N04.761.616', 'N05.715.680'], ['F01.145.126.980.875', 'I01.880.735.856']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Development of a patient-completed admission questionnaire and its comparison with the nursing interview. | To compare the effectiveness of a patient-completed paper-and -pencil questionnaire with the nursing interview in obtaining the admission history, 30 patients newly admitted to a Veterans Administration hospital were asked to complete a questionnaire and were given the routine nursing interview. Data were compared for ... | ['California', 'Hospitalization', 'Hospitals, Veterans', 'Humans', 'Medical History Taking', 'Nurse-Patient Relations', 'Nursing Records', 'Patient Care Planning', 'Patients', 'Surveys and Questionnaires'] | 1,041,622 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.510.180.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.510'], ['F01.829.401.650.600', 'N05.300.660.560'], ['E05.318.308.940.984', 'L01.399.250.900.984', 'N04.452.859.675', 'N05.715.360.300.715.5... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Family accommodation in pediatric anxiety disorders. | BACKGROUND: Family accommodation has been studied in obsessive compulsive disorder using the Family Accommodation Scale (FAS) and predicts greater symptom severity, more impairment, and poorer treatment outcomes. However, family accommodation has yet to be systematically studied among families of children with other an... | ['Adaptation, Psychological', 'Adolescent', 'Anxiety Disorders', 'Anxiety, Separation', 'Child', 'Factor Analysis, Statistical', 'Family', 'Family Health', 'Female', 'Humans', 'Male', 'Parents', 'Psychometrics', 'Reproducibility of Results', 'Severity of Illness Index', 'Social Behavior', 'Surveys and Questionnaires'] | 22,965,863 | [['F01.058'], ['M01.060.057'], ['F03.080'], ['F03.080.300', 'F03.625.047'], ['M01.060.406'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['F01.829.263', 'I01.880.853.150'], ['N01.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.62... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The role of familial sinistrality in cerebral organization. | The literature on the relationship between familial sinistrality (FS) and laterality is conflicting. A large scale investigation employing multiple measures of laterality assessment and rigorous methods of handedness and FS determination was conducted with a normal population of left- and right-handers. The results fai... | ['Adolescent', 'Adult', 'Cerebral Cortex', 'Dichotic Listening Tests', 'Female', 'Functional Laterality', 'Genetics, Behavioral', 'Hand', 'Humans', 'Male', 'Motor Activity', 'Reading', 'Speech', 'Speech Perception'] | 4,000,457 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211.200.885.287.500'], ['E01.370.382.375.200'], ['F02.830.297.425', 'G11.561.225.425'], ['F04.096.276', 'H01.158.273.343.290'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['L01.559.423.557'], ['F01.145.209.908.67... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
[An approach to the morphology of buccal armature of Sergentomyia nankingensis]. | OBJECTIVE: To describe the morphological variation of pointed teeth of buccal armature of Sergentomyia nankingensis in a supplementary study.METHODS: The morphology of Sergentomyia nankingensis was observed and the specimens included S. nankingensis captured from the field as well as the female ones bred in the laborat... | ['Animals', 'Female', 'Male', 'Psychodidae', 'Species Specificity', 'Tooth'] | 12,572,048 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.781'], ['G16.824'], ['A14.549.167.860']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: direct evidence for load-induced fluid flow. | Since proposed by Piekarski and Munro in 1977, load-induced fluid flow through the bone lacunar-canalicular system (LCS) has been accepted as critical for bone metabolism, mechanotransduction, and adaptation. However, direct unequivocal observation and quantification of load-induced fluid and solute convection through ... | ['Animals', 'Biological Transport', 'Bone and Bones', 'Diffusion', 'Fluorescein', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Microscopy, Confocal', 'Osteocytes', 'Osteoporosis', 'Pressure', 'Stress, Mechanical', 'Tibia'] | 20,715,178 | [['B01.050'], ['G03.143'], ['A02.835.232', 'A10.165.265'], ['G01.202', 'G02.196'], ['D02.455.426.779.347.390', 'D03.633.300.953.275.390', 'D04.711.347.390'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['E01.370.350.515.395', 'E05.595.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microfluidic add-on for standard electrophysiology chambers. | We have developed a microfluidic brain slice device (microBSD) that marries an off-the shelf brain slice perfusion chamber with an array of microfluidic channels set into the bottom surface of the chamber substrate. As this device is created through rapid prototyping, once optimized, it is trivial to replicate and shar... | ['Brain', 'Dopamine', 'Electrophysiology', 'Microfluidic Analytical Techniques', 'Microscopy, Fluorescence', 'Sensitivity and Specificity'] | 18,584,078 | [['A08.186.211'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['H01.158.344.528', 'H01.158.782.236'], ['E05.588.465'], ['E01.370.350.515.458', 'E05.595.458'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N0... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Monomeric insulins obtained by protein engineering and their medical implications. | The use of insulin as an injected therapeutic agent for the treatment of diabetes has been one of the outstanding successes of modern medicine. The therapy has, however, had its associated problems, not least because injection of insulin does not lead to normal diurnal concentrations of insulin in the blood. This is es... | ['Animals', 'Blood Glucose', 'Circular Dichroism', 'Computer Graphics', 'Genetic Engineering', 'Humans', 'Insulin', 'Macromolecular Substances', 'Models, Molecular', 'Mutation', 'Protein Conformation', 'Structure-Activity Relationship', 'Swine'] | 3,287,182 | [['B01.050'], ['D09.947.875.359.448.500'], ['E05.196.867.151'], ['L01.224.108', 'L01.296.110'], ['E05.393.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D05'], ['E05.599.595'], ['G05.365.590'], ['G02.111.570.820.709'], ['G02.111.830', 'G07.690.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
C-fos-deficient mouse hippocampal CA3 pyramidal neurons exhibit both enhanced basal and kainic acid-induced excitability. | Excitotoxicity is a process in which glutamate or other excitatory amino acids induce neuronal cell death. To address whether and how c-fos is involved in neuronal excitotoxicity, we previously generated mice in which the c-fos expression is eliminated specifically in the hippocampus. We found that these mutant mice ex... | ['Animals', 'Electroencephalography', 'Evoked Potentials', 'Excitatory Amino Acid Agonists', 'Genes, fos', 'Kainic Acid', 'Male', 'Mice', 'Mice, Neurologic Mutants', 'Organ Culture Techniques', 'Pyramidal Cells', 'Seizures'] | 12,383,919 | [['B01.050'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['G05.360.340.024.340.375.500.791.330'], ['D03.383.773.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.480'], ['E05.481.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An analysis of costs associated with shoulder arthroplasty. | BACKGROUND: The purpose of this study was to identify factors associated with variation in direct costs with shoulder arthroplasty.METHODS: This was a retrospective study of all shoulder arthroplasties performed at a single facility between July 1, 2011, and November 30, 2016. We collected patient factors, indications,... | ['Age Factors', 'Aged', 'Arthroplasty, Replacement, Shoulder', 'Bone Transplantation', 'Costs and Cost Analysis', 'Direct Service Costs', 'Female', 'Humans', 'Male', 'Middle Aged', 'Operating Rooms', 'Osteoarthritis', 'Reoperation', 'Retrospective Studies', 'Rotator Cuff Injuries', 'Shoulder Joint', 'Shoulder Prosthesi... | 30,827,836 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E04.555.110.110.299', 'E04.650.110.299', 'E04.680.101.110.299'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['N03.219.151'], ['N03.219.151.400.325', 'N05.300.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], [... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling. | Wnt-5a is a representative ligand that activates a beta-catenin-independent pathway in Wnt signalling. In the present paper, the roles of the post-translational modifications in the actions of Wnt-5a were investigated. We found that Wnt-5a is modified with palmitate at Cys104 and glycans at Asn114, Asn120, Asn311 and A... | ['Amino Acid Sequence', 'Animals', 'Cell Line', 'Cell Movement', 'Fatty Acids, Monounsaturated', 'Glycosylation', 'Humans', 'Mice', 'Molecular Sequence Data', 'Protein Binding', 'Protein Processing, Post-Translational', 'Proto-Oncogene Proteins', 'Sequence Alignment', 'Signal Transduction', 'TCF Transcription Factors',... | 17,117,926 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['D10.251.355.325'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['G02.111.679', 'G03.808']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of antibiogram, staphylococcal enterotoxin productivity, and coagulase genotypes among Staphylococcus aureus isolated from animal and vegetable sources in Korea. | Staphylococcal food poisoning is caused by enterotoxin-producing Staphylococcus aureus. We investigated the prevalence of such organisms in samples of bovine mastitic milk (n = 714), raw meat (n = 139), and vegetables (n = 616). We determined the degrees of relatedness of isolates as indicated by antibiogram, staphyloc... | ['Animals', 'Anti-Bacterial Agents', 'Cattle', 'Coagulase', 'Consumer Product Safety', 'Drug Resistance, Bacterial', 'Enterotoxins', 'Female', 'Food Contamination', 'Food Handling', 'Genotype', 'Humans', 'Korea', 'Meat', 'Microbial Sensitivity Tests', 'Milk', 'Polymorphism, Restriction Fragment Length', 'Refrigeration'... | 18,044,432 | [['B01.050'], ['D27.505.954.122.085'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.277.656.300.174', 'D12.776.097.181'], ['N06.850.210'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['D23.946.330'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['J01.576.423.200'], ['G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Crystal structures of cyanobacterial light-dependent protochlorophyllide oxidoreductase. | The reduction of protochlorophyllide (Pchlide) to chlorophyllide (Chlide) is the penultimate step of chlorophyll biosynthesis. In oxygenic photosynthetic bacteria, algae, and plants, this reaction can be catalyzed by the light-dependent Pchlide oxidoreductase (LPOR), a member of the short-chain dehydrogenase superfamil... | ['Catalysis', 'Chlorophyll', 'Crystallography, X-Ray', 'Cyanobacteria', 'Light', 'Models, Molecular', 'NADP', 'Oxidoreductases Acting on CH-CH Group Donors', 'Protein Conformation', 'Protochlorophyllide', 'Protons', 'Synechocystis', 'Thermosynechococcus'] | 32,234,783 | [['G02.130'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['E05.196.309.742.225'], ['B03.280', 'B03.440.475.100'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.599.595'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High BRAFV600E mutation frequency in Chinese patients with papillary thyroid carcinoma increases diagnostic efficacy in cytologically indeterminate thyroid nodules. | To estimate the BRAFV600E mutation frequency in Chinese patients with papillary thyroid carcinoma (PTC), and the diagnostic value of BRAFV600E mutation status in thyroid nodules with indeterminate TBSRTC categories.A total of 4875 consecutive samples for thyroid ultrasound-guided fine-needle aspiration cytology (FNAC) ... | ['Adolescent', 'Adult', 'Aged', 'Asian Continental Ancestry Group', 'Biomarkers, Tumor', 'Biopsy, Fine-Needle', 'Child', 'China', 'DNA Mutational Analysis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Proto-Oncogene Proteins B-raf', 'Sensitivity and Specificity', 'Thyroid Cancer, Papillary', 'Thyroid Neopla... | 31,305,422 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.686.508.200'], ['D23.101.140'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['M01.06... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
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