Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Determination of nitrofuran and chloramphenicol residues by high resolution mass spectrometry versus tandem quadrupole mass spectrometry. | An ultra-high performance liquid chromatography based method, coupled to high resolution mass spectrometry (UHPLC-HRMS), was developed to permit the detection and quantification of various nitrofuran and chloramphenicol residues in a number of animal based food products. This method is based on the hydrolysis of covale... | ['Chloramphenicol', 'Mass Spectrometry', 'Nitrofurans', 'Tandem Mass Spectrometry'] | 25,682,427 | [['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['E05.196.566'], ['D02.640.600', 'D03.383.312.649'], ['E05.196.566.880']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of in vitro cultivation and Mycoplasma pneumoniae infection on intracellular cyclic AMP levels in hamster tracheal organ cultures. | Exogenous cyclic AMP and dibutyryl cyclic AMP decreased the relative ciliary activity values of tracheal organ cultures. In contrast, theophylline and cholera toxin were not ciliostatic. The use of a radioimmunoassay for cyclic AMP indicated that all of the tested substances increased intracellular cyclic AMP levels to... | ['Animals', 'Bucladesine', 'Cholera Toxin', 'Cilia', 'Cricetinae', 'Cyclic AMP', 'Mycoplasma', 'Organ Culture Techniques', 'Theophylline', 'Trachea'] | 222,670 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Update From the Advisory Committee on Immunization Practices. | The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group usually has 15 voting members, each of whom is appointed to a 4-year term. ACIP members and Centers for Disease Control... | ['Adolescent', 'Adult', 'Advisory Committees', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Immunization', 'Immunization Schedule', 'Infant', 'Male', 'Middle Aged', 'Pediatrics', 'Practice Guidelines as Topic', 'Societies, Medical', 'United States', 'Vaccination', 'Vaccines', 'Vaccines, Combined', 'Young A... | 31,367,738 | [['M01.060.057'], ['M01.060.116'], ['N03.706.742.500'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['E02.095.465.425.400.470', 'E05.478.550.545'],... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Analysis of the Raman intensities near the phase transitions in ammonium halides. | This study concentrates on the temperature dependence of the Raman intensities for the lattice modes in ammonium halides (NH(4)Cl and NH(4)Br) close to phase transitions. We predict their intensities using the results of a shell model for the Raman polarizability within the framework of an Ising pseudospin-phonon coupl... | ['Ammonium Chloride', 'Bromides', 'Crystallization', 'Models, Chemical', 'Phase Transition', 'Pressure', 'Quaternary Ammonium Compounds', 'Spectrum Analysis, Raman', 'Temperature', 'Thermodynamics'] | 18,356,099 | [['D01.210.450.150.050', 'D01.625.062.249'], ['D01.139.300.050', 'D01.248.497.158.125'], ['E05.196.300', 'G02.171'], ['E05.599.495'], ['G01.645', 'G02.734'], ['G01.374.715'], ['D01.625.062.500', 'D02.092.877', 'D02.675.276'], ['E05.196.822.860', 'E05.196.867.890'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.75... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Antibody response after intradermal administration of recombinant hepatitis B vaccine in children. | Intradermal vaccination with recombinant hepatitis B vaccine was performed in 33 children (mean age 3.3 years). A 2 micrograms dose was given at 0, 1 and 6 months and antibody responses were determined 20 months after the initial dose. In 32/33 children, serum antibodies to HBs were demonstrated, with a geometric mean ... | ['Child Day Care Centers', 'Child, Preschool', 'Female', 'Hepatitis B Antibodies', 'Hepatitis B Surface Antigens', 'Hepatitis B Vaccines', 'Humans', 'Infant', 'Injections, Intradermal', 'Male', 'Vaccination', 'Vaccines, Synthetic', 'Viral Hepatitis Vaccines'] | 2,148,015 | [['J03.160', 'N02.421.143.098'], ['M01.060.406.448'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D12.776.377.715.548.114.254.450.504'], ['D23.050.327.495.500.475'], ['D20.215.894.899.955.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.319.267.530.620.4... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Myocardial infarction in Graves' disease without coronary artery disease. | A 45-year-old female without coronary risk factors showed a 20 kg decrease in body weight, hyperhydrosis, palpitations and dyspnea on exertion for 2 months, and nocturnal dyspnea for 1 month before admission. She did not notice chest pain indicative myocardial infarction or fever suggestive myocarditis. Graves' disease... | ['Coronary Disease', 'Female', 'Graves Disease', 'Humans', 'Middle Aged', 'Myocardial Infarction', 'Thyrotoxicosis'] | 3,626,027 | [['C14.280.647.250', 'C14.907.585.250'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['C19.874.397.685']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In vitro anti-nephrotoxic potential of Ammi visnaga, Petroselinum crispum, Hordeum vulgare, and Cymbopogon schoenanthus seed or leaf extracts by suppressing the necrotic mediators, oxidative stress and inflammation. | BACKGROUND: The kidney is an essential organ required by the body to perform several important functions. Nephrotoxicity is one of the most prevailing kidney complications that result from exposure to an extrinsic or intrinsic toxicant, which increase the need for the acquisition of proper remedies. Recently, natural r... | ['Ammi', 'Animals', 'Antioxidants', 'Chlorocebus aethiops', 'Cymbopogon', 'Hordeum', 'Kidney', 'NF-kappa B', 'Nitric Oxide', 'Oxidative Stress', 'Petroselinum', 'Phenols', 'Plant Extracts', 'Plant Leaves', 'Seeds', 'Vero Cells'] | 31,238,921 | [['B01.650.940.800.575.912.250.075.039'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['B01.650.940.800.575.912.250.822.266'], ['B01.650.940.800.575.912.250.822.481'], ['A05.810.453'], ['D05.500.672', 'D12.776.260.600', 'D12.776.66... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fuzzy logic applied to prospecting for areas for installation of wood panel industries. | Prospecting for suitable areas for forestry operations, where the objective is a reduction in production and transportation costs, as well as the maximization of profits and available resources, constitutes an optimization problem. However, fuzzy logic is an alternative method for solving this problem. In the context o... | ['Crops, Agricultural', 'Eucalyptus', 'Forestry', 'Fuzzy Logic', 'Wood'] | 28,237,845 | [['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['B01.650.940.800.575.912.250.773.366'], ['J01.576.430'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['A18.450.500.500', 'J01.637.241.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Improved contrast of enhancing brain lesions using contrast-enhanced T1-weighted fast spin-echo MR imaging. | OBJECTIVE: The purpose of this study was to evaluate the ability of T1-weighted fast spin-echo MR sequences to provide improved contrast-to-noise ratios for contrast-enhanced lesions during acquisition times shorter than those used for conventional T1-weighted spin-echo MR sequences.SUBJECTS AND METHODS: We compared co... | ['Adult', 'Aged', 'Brain', 'Brain Diseases', 'Female', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged'] | 9,124,121 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['C10.228.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'], ['M01.060.116.630']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Determinants of mortality of preterm babies in the university of Ilorin Teaching Hospital, Ilorin Nigeria. | AIMS AND OBJECTIVES: A prospective study to identify the determinants of mortality among 185 preterm babies at the University of Ilorin Teaching Hospital, Ilorin.SUBJECTS AND METHODS: Data on 185 preterm babies and their mothers were collected over a nine month period in a tertiary hospital to identify the determinants... | ['Adolescent', 'Adult', 'Cause of Death', 'Female', 'Gestational Age', 'Hospitals, Teaching', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Infant, Premature', 'Logistic Models', 'Male', 'Maternal Age', 'Nigeria', 'Prospective Studies', 'Risk Factors', 'Socioeconomic Factors', 'Young Adult'] | 21,809,607 | [['M01.060.057'], ['M01.060.116'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['G07.345.500.325.235.968', 'G08.686.320'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.308.985.550... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Regional left ventricular systolic function in patients with segmental early relaxation and normal coronary arteries. | The purpose of the study was to determine whether regional differences of left ventricular systolic function exist in patients with normal coronary arteries who manifest segmental early relaxation. The presence or absence of segmental early relaxation was determined angiographically in 16 patients with normal coronary ... | ['Adult', 'Aged', 'Coronary Vessels', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Stroke Volume', 'Systole', 'Ventricular Function'] | 6,736,453 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.269', 'A07.015.908.194'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.330.580', 'G11.427.494.570'], ['E01.370.370.380.150.700', 'G09.330.380.124.882'], ['G09.330.580.880', 'G11.427.494.570.880'], ['G09.330.955']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats. | D2C7-(scdsFv)-PE38KDEL (D2C7-IT) is a novel immunotoxin that reacts with wild-type epidermal growth factor receptor (EGFRwt) and mutant EGFRvIII proteins overexpressed in glioblastomas. This study assessed the toxicity of intracerebral administration of D2C7-IT to support an initial Food and Drug Administration Investi... | ['Animals', 'Brain', 'Convection', 'Drug Delivery Systems', 'Drug Evaluation, Preclinical', 'Female', 'Immunoconjugates', 'Immunotoxins', 'Inhibitory Concentration 50', 'Injections, Intraventricular', 'Male', 'Rats, Sprague-Dawley', 'Single-Chain Antibodies'] | 26,728,879 | [['B01.050'], ['A08.186.211'], ['G01.906.230'], ['E02.319.300'], ['E05.290.750', 'E05.337.550'], ['D12.776.124.790.651.114.580', 'D12.776.377.715.548.114.580', 'D27.888.569.257'], ['D12.776.124.790.651.114.580.450', 'D12.776.377.715.548.114.580.450', 'D27.888.569.257.500'], ['E05.940.350', 'G07.690.936.563'], ['E02.319... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Presentation of severe haemophilia--a role for accident and emergency doctors? | BACKGROUND: The management of haemophilia has changed dramatically over the years and is constantly being improved. This study set out to discover if the diagnosis of haemophilia was being made early enough in those with no family history and looked at the different modes of presentation.METHOD: A questionnaire was sen... | ['Adolescent', 'Child', 'Diagnostic Errors', 'Emergencies', 'England', 'Hemophilia A', 'Hemophilia B', 'Humans', 'Male', 'Medicine', 'Retrospective Studies', 'Specialization', 'Time Factors'] | 11,435,355 | [['M01.060.057'], ['M01.060.406'], ['E01.354', 'N02.421.450.280'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['Z01.542.363.300'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['C15.378.100.100.510', 'C15.378.100.141.510', 'C15.378.463.510', 'C16.320.099.510', 'C16.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Persistent sodium current is a nonsynaptic substrate for long-term associative memory. | Although synaptic plasticity is widely regarded as the primary mechanism of memory [1], forms of nonsynaptic plasticity, such as increased somal or dendritic excitability or membrane potential depolarization, also have been implicated in learning in both vertebrate and invertebrate experimental systems [2-7]. Compared ... | ['Animals', 'Conditioning, Classical', 'Lymnaea', 'Membrane Potentials', 'Memory', 'Neurons', 'Sodium'] | 18,701,288 | [['B01.050'], ['F02.463.425.179.308'], ['B01.050.500.644.400.750.645'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['F02.463.425.540'], ['A08.675', 'A11.671'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cardiology telemedicine solutions - opinion of the experts of the Committee of Informatics and Telemedicine of Polish Society of Cardiology, Section of Non-invasive Electrocardiology and Telemedicine of Polish Society of Cardiology and Clinical Sciences C]. | For several years, we have observed the dynamic development of technologies that allow patients to access medical care from the comfort of their homes, without direct contact with the doctor. Innovative solutions based on telemedicine improve care coordination and communication among clinicians, patients, and their fam... | ['Cardiology', 'Humans', 'Poland', 'Societies, Medical', 'Telemedicine'] | 29,441,511 | [['H02.403.429.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.679'], ['N03.540.828.589'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800']] | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
[Anatomical basis for the newly developed facelifting]. | OBJECTIVE: To investigate the relationship between the SMAS and the facial nerve divisions in the cheek area.METHOD: We dissected 12 cadaver heads(24 sides).RESULTS: 1. SMAS distributed over the middle face. It became thinner as it extended forward and there was a small aperture lateral to the mouth. The branches of fa... | ['Adult', 'Aged', 'Facial Nerve', 'Female', 'Humans', 'Male', 'Middle Aged', 'Rhytidoplasty'] | 11,263,318 | [['M01.060.116'], ['M01.060.116.100'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.218.765', 'E04.680.275.700']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Purification and properties of phosphofructokinase from Dictyostelium discoideum. | Phosphofructokinase (PFruK) from the slime mold Dictyostelium discoideum has been purified to homogeneity over 15,000-fold with a 29% yield. Sodium dodecyl sulfate/polyacrylamide gel electrophoresis of the final preparation revealed a single band of 95 kDa. The native molecular mass was determined by gel filtration to ... | ['Adenosine Triphosphate', 'Amino Acids', 'Animals', 'Chromatography, Gel', 'Cyclic AMP', 'Dictyostelium', 'Electrophoresis, Polyacrylamide Gel', 'Hydrogen-Ion Concentration', 'Immunosorbent Techniques', 'Macromolecular Substances', 'Molecular Weight', 'Phosphofructokinase-1', 'Phosphorylation', 'Protein Kinases', 'Seq... | 7,813,455 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.125'], ['B01.050'], ['E05.196.181.400.250'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.046.550.200.300'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.300'], ['E05.478.566... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reconstitution of thromboxane A2 receptor-stimulated phosphoinositide hydrolysis in isolated platelet membranes: involvement of phosphoinositide-specific phospholipase C-beta and GTP-binding protein Gq. | Activation of human platelets by the arachidonic acid metabolite thromboxane A2 and the thromboxane A2 mimic U46619 is mediated through phosphoinositide-specific phospholipase C-catalysed hydrolysis of phosphoinositides. We have established conditions to reconstitute U46619-stimulated phosphoinositide breakdown by addi... | ['Blood Platelets', 'Cell Membrane', 'GTP-Binding Proteins', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Guanosine Triphosphate', 'Humans', 'Hydrolysis', 'Isoenzymes', 'Kinetics', 'Phosphatidylinositol Diacylglycerol-Lyase', 'Phosphatidylinositols', 'Phosphoric Diester Hydrolases', 'Prostaglandin Endoperoxides, Synthetic',... | 8,385,934 | [['A11.118.188', 'A15.145.229.188'], ['A11.284.149'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D02.886.765.380', 'D13.695.667.454.504.380', 'D13.695.827.426.504.380', 'D13.695.900.380'], ['D03.633.100.759.646.454.504', 'D13.695.667.454.504', 'D13.695.827.426.504'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serious toxicity associated with annular microwave array induction of whole-body hyperthermia in normal dogs. | Using a regional annular microwave array it was possible to produce a systemic temperature of 42 degrees C in approximately 80 min with applied net power levels of approximately 150 W. Resulting temperature distributions were non-uniform. Sites within the array were above systemic temperature during heating but approxi... | ['Animals', 'Body Temperature', 'Dogs', 'Hyperthermia, Induced', 'Microwaves', 'Organ Specificity', 'Wounds and Injuries'] | 1,545,161 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.565'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['G07.650'], ['C26']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Primary pineal tumors: outcome and prognostic factors--a study from the Rare Cancer Network (RCN). | PURPOSE: To better define outcome and prognostic factors in primary pineal tumors.MATERIALS AND METHODS: Thirty-five consecutive patients from seven academic centers of the Rare Cancer Network diagnosed between 1988 and 2006 were included. Median age was 36 years. Surgical resection consisted of biopsy in 12 cases and ... | ['Adolescent', 'Adult', 'Aged', 'Chemotherapy, Adjuvant', 'Child', 'Child, Preschool', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pinealoma', 'Prognosis', 'Treatment Outcome'] | 22,914,906 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.186.170', 'E02.319.170'], ['M01.060.406'], ['M01.060.406.448'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Perception among upper middle class adolescent in Bombay regarding sex and sexuality. | The study was carried out among the adolescents in respect to their beliefs about sexual behavior and their intended decision with regard to engaging in sexual activity. Both male and female respondents indicated that they believe that individuals of their age should wait until they are older before engaging in sexual ... | ['Adolescent', 'Attitude', 'Female', 'Humans', 'Income', 'India', 'Male', 'Sex Factors', 'Sexual Behavior', 'Social Class'] | 16,479,912 | [['M01.060.057'], ['F01.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['Z01.252.245.393'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.802'], ['I01.880.853.996.755', 'N01.824.782']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Kinematics of passive flexion following balanced and overstuffed fixed bearing unicondylar knee arthroplasty. | INTRODUCTION: Progression of osteoarthritis in the unreplaced compartment following unicondylar knee arthroplasty (UKA) may be hastened if kinematics is disturbed following UKA implantation. The purpose of this study was to analyze tibiofemoral kinematics of the balanced and overstuffed UKA in comparison with the nativ... | ['Arthroplasty, Replacement, Knee', 'Biomechanical Phenomena', 'Cadaver', 'Female', 'Humans', 'Knee Joint', 'Knee Prosthesis', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Range of Motion, Articular'] | 26,358,244 | [['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['E07.695.400.410'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E01.370.600.700', 'G11.427.760']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
White Matter Changes in Tinnitus: Is It All Age and Hearing Loss? | Tinnitus is a condition characterized by the perception of auditory phantom sounds. It is known as the result of complex interactions between auditory and nonauditory regions. However, previous structural imaging studies on tinnitus patients showed evidence of significant white matter changes caused by hearing loss tha... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Corpus Callosum', 'Diffusion Tensor Imaging', 'Female', 'Hearing Loss', 'Humans', 'Male', 'Middle Aged', 'Tinnitus', 'White Matter', 'Young Adult'] | 26,477,359 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['A08.186.211.200.885.800.750'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Establishment and maintenance of behavioural dominance in male mice infected with Trichinella spiralis. | Trichinella spiralis infections influenced the establishment and maintenance of behavioural dominance among outbred male mice. Infected animals assumed a subordinate status when challenged by normal or more lightly infected conspecifics both in an unfamiliar test arena and in their established home cages. These effects... | ['Animals', 'Dominance-Subordination', 'Male', 'Mice', 'Social Dominance', 'Time Factors', 'Trichinellosis'] | 6,856,335 | [['B01.050'], ['F01.145.813.650.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['F01.145.813.650'], ['G01.910.857'], ['C01.610.335.508.100.275.882']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retrospective diagnosis of congenital cytomegalovirus infection at a school for the deaf by using preserved dried umbilical cord. | A retrospective diagnosis of congenital cytomegalovirus infection was made for 3 of 26 students (12%) with either bilateral profound or severe sensorineural hearing loss at a School for the Deaf in Japan by detecting viral DNA with real-time polymerase chain reaction from dried umbilical cords that had been preserved a... | ['Adolescent', 'Child', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'DNA, Viral', 'Female', 'Fetal Blood', 'Hearing Loss, Sensorineural', 'Humans', 'Infant, Newborn', 'Japan', 'Male', 'Neonatal Screening', 'Persons With Hearing Impairments', 'Prevalence', 'Retrospective Studies', 'Reverse Transcriptase Polymerase ... | 19,840,618 | [['M01.060.057'], ['M01.060.406'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['D13.444.308.568'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['Z01.252.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pattern of renal amyloidosis in South Africa. | BACKGROUND: Kidney disease is a serious manifestation of systemic amyloidosis and a major cause of morbidity and mortality. Tuberculosis (TB) occurs up to 27 times more commonly in human immunodeficiency virus (HIV) infected patients and is also an important cause of renal amyloid; there are however no reports of renal... | ['Adult', 'Aged', 'Aged, 80 and over', 'Amyloidosis', 'Biopsy', 'Female', 'Fluorescent Antibody Technique', 'HIV Infections', 'Humans', 'Immunoglobulin Light-chain Amyloidosis', 'Immunohistochemistry', 'Kidney', 'Kidney Diseases', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Prevalence', 'Retrospective Studies', 'So... | 31,706,285 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C18.452.845.500'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Adverse outcome of methotrexate and mini pulse betamethasone in the treatment of lichen planus. | The objectives of this study were to compare the adverse outcome of methotrexate and mini pulse betamethasone therapy in the treatment of lichen planus. It was a clinical trial conducted in the department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka, from January 2009 to December 2... | ['Adolescent', 'Adult', 'Anti-Inflammatory Agents', 'Bangladesh', 'Betamethasone', 'Dermatologic Agents', 'Female', 'Humans', 'Lichen Planus', 'Male', 'Methotrexate', 'Middle Aged', 'Prospective Studies', 'Young Adult'] | 23,923,408 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.158'], ['Z01.252.245.131'], ['D04.210.500.745.432.769.199', 'D04.210.500.908.093'], ['D27.505.954.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.859.475.560'], ['D03.633.100.733.631.192.500'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The effect of dexmedetomidine on autophagy and apoptosis in intestinal ischemia reperfusion-induced lung injury]. | OBJECTIVE: To investigate the protective effects of dexmedetomidine against autophagy and apoptosis in intestinal ischemia reperfusion (I/R)-induced lung injury.METHODS: Twenty-four SD rats were randomly and equally divided into 4 groups according to the random number table: control group, I/R group, small dose of dexm... | ['Animals', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Autophagy', 'Beclin-1', 'Caspase 3', 'Dexmedetomidine', 'Lung', 'Lung Injury', 'Microtubule-Associated Proteins', 'Rats', 'Rats, Sprague-Dawley', 'Reperfusion Injury'] | 26,703,944 | [['B01.050'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['G04.011'], ['D12.644.360.075.335', 'D12.776.094.500', 'D12.776.476.075.335'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D03.383.129.308.245']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacterial flagellin triggers cardiac innate immune responses and acute contractile dysfunction. | BACKGROUND: Myocardial contractile failure in septic shock may develop following direct interactions, within the heart itself, between molecular motifs released by pathogens and their specific receptors, notably those belonging to the toll-like receptor (TLR) family. Here, we determined the ability of bacterial flagell... | ['Animals', 'Cell Line', 'Cells, Cultured', 'Cytokines', 'Flagellin', 'Heart', 'Humans', 'Immunity, Innate', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Knockout', 'Myoblasts, Cardiac', 'Myocardial Contraction', 'Myocardium', 'Myocytes, Cardiac', 'NF-kappa B', 'Rats', 'Salmonella', 'Salmonella Infections', 'Shock, Se... | 20,856,884 | [['B01.050'], ['A11.251.210'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.776.097.380'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.564'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lapaquistat acetate: development of a squalene synthase inhibitor for the treatment of hypercholesterolemia. | BACKGROUND: Lapaquistat acetate is a squalene synthase inhibitor investigated for the treatment of hypercholesterolemia.METHODS AND RESULTS: This report summarizes the phase 2 and 3 results from the lapaquistat clinical program, which was halted at an advanced stage as a result of potential hepatic safety issues. Effic... | ['Adult', 'Aged', 'Anticholesteremic Agents', 'Clinical Trials, Phase II as Topic', 'Clinical Trials, Phase III as Topic', 'Farnesyl-Diphosphate Farnesyltransferase', 'Female', 'Humans', 'Hypercholesterolemia', 'Liver Diseases', 'Male', 'Middle Aged', 'Oxazepines', 'Piperidines', 'Randomized Controlled Trials as Topic'... | 21,518,985 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['E05.318.372.250.250.210', 'N05.715.360.330.250.250.210', 'N06.850.520.450.250.250.210'], ['E05.318.372.250.250.220', 'N05.715.360.330.250.250.220', 'N06.850.520.450.250.250.220'], ['D08.811.913.225.431'], ['B01.050.150.900.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Treatment of schistosomiasis-associated pulmonary hypertension. | Schistosomiasis mansoni is the third most prevalent endemic parasitic disease in the world. It is estimated that over 200 million people are infected with parasites belonging to one of the Schistosoma species. Of those, 270,000 people (4.6%) suffer from pulmonary arterial hypertension, which is associated with the hepa... | ['Adult', 'Exercise Test', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Phosphodiesterase 5 Inhibitors', 'Piperazines', 'Purines', 'Schistosomiasis', 'Sildenafil Citrate', 'Sulfones', 'Walking'] | 21,537,664 | [['M01.060.116'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['D27.505.519.389.735.500'], ['D03.383.606'], ['D03.633.100.759'], ['C01.610.335.865.859', 'C01.920.922'], ['D02.065.884.675', 'D02.886.590.700.675', 'D03... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Microwave transurethral thermotherapy in the treatment of prostatic adenoma]. | We report 195 patients with prostatic adenoma treated with microwave transurethral thermotherapy. All patients were initially subjected to a clinical assessment including Madsen-Iversen symptom score, digital rectal examination, measurement of urine flow rate and residual urine volume, transrectal prostatic ultrasound ... | ['Aged', 'Diathermy', 'Follow-Up Studies', 'Humans', 'Hyperthermia, Induced', 'Male', 'Microwaves', 'Middle Aged', 'Prognosis', 'Prostatic Hyperplasia', 'Treatment Outcome'] | 7,528,937 | [['M01.060.116.100'], ['E02.565.280'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['M01.060.116.630'], ['E01.789'], ['C12.294.565.500']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Steroid metabolism in pregnant hamster. II. The metabolism of androgens by the hamster placenta. | The biotransformation of [4-14C] labelled dehydroepiandrosterone, testosterone and androstenedione by quartered placentae of 12 and 15 day pregnant hamsters was investigated in vitro. The above androgens were extensively metabolized by placental preparations and resulting products were identified by chromatographic and... | ['Androgens', 'Androstenedione', 'Animals', 'Cricetinae', 'Dehydroepiandrosterone', 'Etiocholanolone', 'Female', 'Gestational Age', 'In Vitro Techniques', 'Mesocricetus', 'Placenta', 'Pregnancy', 'Pregnancy, Animal', 'Testosterone'] | 6,455,287 | [['D27.505.696.399.472.161'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.952'], ['D04.210.500.05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Down-regulation of basic fibroblast growth factor production from cartilage by excessive mechanical stress. | BACKGROUND: We examined the effect of excessive stress on the production of basic fibroblast growth factor (bFGF) by bovine cartilage.METHODS: Bovine articular carpal bone was harvested and cut into 1 cm thick slices horizontally. Continuous compressive stress (0, 2, 20 MPa) was loaded on the cartilage of the carpal bo... | ['Animals', 'Carpal Joints', 'Cartilage, Articular', 'Cattle', 'Down-Regulation', 'Enzyme Inhibitors', 'Fibroblast Growth Factor 2', 'Interleukin-4', 'Nitric Oxide', 'Stress, Mechanical', 'Tissue Culture Techniques', 'omega-N-Methylarginine'] | 16,307,186 | [['B01.050'], ['A02.835.583.405.174'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.500.380.271'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D27.505.519.389'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['D12.644.276.374.465.186', 'D12.776.467.374.465.178', 'D23.5... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Randomized trial to reduce emergency visits or hospital admissions using telephone coaching to complex patients. | Background: Comorbidity remains a matter of international interest, given growing prevalence of chronic conditions.Objective: To evaluate the impact that adding a telephone coaching intervention by a family physician to usual care has on reducing resource consumption and improving health status, caregiver burden and qu... | ['Aged, 80 and over', 'Case Management', 'Chronic Disease', 'Comorbidity', 'Emergency Service, Hospital', 'Female', 'Health Status', 'Humans', 'Male', 'Patient Admission', 'Physicians, Family', 'Quality of Life', 'Referral and Consultation', 'Spain', 'Surveys and Questionnaires', 'Telephone'] | 27,920,119 | [['M01.060.116.100.080'], ['N04.590.233.624.250'], ['C23.550.291.500'], ['N05.715.350.225', 'N06.850.490.687'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.600', 'N02.421.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Drug-drug interaction between crizotinib and entecavir via renal secretory transporter OCT2. | Both entecavir and crizotinib are substrates of organic cation transporter 2 (OCT2). The aim of present study was to investigate the mechanisms of drug interactions between these two drugs. Kinetic analysis of entecavir on crizotinib uptake was conduct. Plasma concentration of crizotinib in rats and lung cancer patient... | ['Animals', 'Biological Transport', 'Crizotinib', 'Drug Interactions', 'Guanine', 'HEK293 Cells', 'Humans', 'Kidney', 'Kinetics', 'Lung Neoplasms', 'Male', 'Organic Cation Transporter 2', 'Rats', 'Rats, Sprague-Dawley'] | 31,740,393 | [['B01.050'], ['G03.143'], ['D03.383.621.154', 'D03.383.725.050.263'], ['G07.690.773.968'], ['D03.633.100.759.758.399.454'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['G01.374.661', 'G02.111.490'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The efficacy of acarbose in type 2 diabetes mellitus in Jamaica. | The efficacy and tolerability of acarbose was studied in type 2 diabetic patients eating a typical Jamaican diet. The study was an open label parallel group study without placebo control. Of the 51 subjects recruited, five (9.8%) did not complete the study and were excluded from further analysis. Six (13%) of the remai... | ['Acarbose', 'Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Diet', 'Drug Therapy, Combination', 'Female', 'Flatulence', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Jamaica', 'Male', 'Middle Aged', 'Treatment Outcome'] | 11,211,536 | [['D09.698.629.802.100'], ['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203.650.240'], ['E02.319.310'], ['C23.888.821.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['Z01.107.084.900.525',... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Endovascular repair of a Streptococcus pneumonia-induced aortitis complicated by an iliacocaval fistula. | PURPOSE: To describe the successful endovascular treatment and follow-up of a patient with a Streptococcus pneumonia-induced right iliacocaval fistula.CASE REPORT: A 82-year-old man was diagnosed with a right iliacocaval fistula, as a result of Streptococcus pneumoniae infection of the distal aorta and proximal right c... | ['Aged, 80 and over', 'Anti-Bacterial Agents', 'Aortitis', 'Arteriovenous Fistula', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Endovascular Procedures', 'Fluorodeoxyglucose F18', 'Humans', 'Iliac Artery', 'Male', 'Multimodal Imaging', 'Pneumococcal Infections', 'Positron-Emission Tomography', '... | 22,956,511 | [['M01.060.116.100.080'], ['D27.505.954.122.085'], ['C14.907.109.320', 'C14.907.940.080'], ['C14.240.850.750.147', 'C14.240.850.984.750', 'C14.907.150.125', 'C14.907.933.555', 'C16.131.240.850.750.125', 'C23.300.575.950.250'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['E04.100.814.529', 'E04.502.382'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Choroidal Microvascular Dropout in Primary Angle Closure Glaucoma. | PURPOSE: To determine the prevalence and factors associated with the presence of choroidal microvascular dropout (CMvD) in primary angle-closure glaucoma (PACG) eyes compared to primary open-angle glaucoma (POAG) eyes.DESIGN: Cross-sectional study.METHODS: Thirty-six POAG eyes (36 patients) and 28 PACG eyes (28 patient... | ['Aged', 'Choroid', 'Ciliary Arteries', 'Cross-Sectional Studies', 'Female', 'Fluorescein Angiography', 'Glaucoma, Angle-Closure', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Male', 'Microvessels', 'Middle Aged', 'Optic Disk', 'Peripheral Vascular Diseases', 'Prevalence', 'Prospective Studies', 'Tomograp... | 30,552,893 | [['M01.060.116.100'], ['A09.371.894.223'], ['A07.015.114.248'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.370.050.350', 'E01.370.380.250'], ['C11.525.381.056'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['A07.015.461'], ['M01.060.11... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Infertility and breast cancer: a population-based case-control study. | To investigate whether a history of infertility affects a woman's risk of developing breast cancer, the authors analyzed case-control data collected between 1980 and 1982 as part of the Cancer and Steroid Hormone Study. The 4,730 cases were women aged 20-54 years with a first diagnosis of breast cancer ascertained from... | ['Adult', 'Breast Neoplasms', 'Case-Control Studies', 'Female', 'Humans', 'Infertility, Female', 'Medical Records', 'Middle Aged', 'Risk Factors', 'Surveys and Questionnaires', 'Time Factors'] | 2,403,111 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500', 'N06.850.520.308.940.968'], ['M01.060.116.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mixed reflux of gastric and duodenal juices is more harmful to the esophagus than gastric juice alone. The need for surgical therapy re-emphasized. | OBJECTIVE: The author's goal was to determine the role of duodenal components in the development of complications of gastroesophageal reflux disease.SUMMARY AND BACKGROUND DATA: There is a disturbing increase in the prevalence of complications, specifically the development of Barrett's esophagus among patients with gas... | ['Adult', 'Aged', 'Barrett Esophagus', 'Bilirubin', 'Duodenogastric Reflux', 'Esophagitis, Peptic', 'Esophagus', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Middle Aged', 'Monitoring, Ambulatory'] | 7,574,932 | [['M01.060.116'], ['M01.060.116.100'], ['C04.834.154', 'C06.405.117.102'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['C06.405.469.275.700', 'C06.405.748.240'], ['C06.405.117.620.420', 'C06.405.205.663.420', 'C06.405.469.275.800.523', 'C06.405.748.586.524'], [... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical and molecular insights into Glanzmann's thrombasthenia in China. | Glanzmann's thrombasthenia (GT) is a rare bleeding disorder characterized by spontaneous mucocutaneous bleeding. The disorder is caused by quantitative or qualitative defects in integrin áIIbâ3 (encoded by ITGA2B and ITGB3) on the platelet and is more common in consanguineous populations. However, the prevalence rate a... | ['Adolescent', 'Adult', 'Blood Platelets', 'Child', 'Child, Preschool', 'China', 'Female', 'Frameshift Mutation', 'Genetic Predisposition to Disease', 'Genotype', 'Hemorrhage', 'Humans', 'Infant', 'Integrin alpha2', 'Integrin beta3', 'Male', 'Middle Aged', 'Mutation, Missense', 'Platelet Aggregation', 'Thrombasthenia',... | 29,675,921 | [['M01.060.057'], ['M01.060.116'], ['A11.118.188', 'A15.145.229.188'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['G05.365.590.265'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D12.776.543.750.705.408.100.350... | ['Named Groups [M]', 'Anatomy [A]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Excessive proliferation of peripelvic fat of the kidney. | Excessive proliferation of the peripelvic fat of the kidney (EPPF) is a benign process with an innocuous effect on the patient. However, this condition may assume major clinical significance by producing pyelocalyceal deformities that may be mistaken for true renal masses. Rarely, EPPF may masquerade as a renal pelvic ... | ['Adipose Tissue', 'Aged', 'Atrophy', 'Diagnosis, Differential', 'Diagnostic Errors', 'Humans', 'Kidney Diseases', 'Kidney Neoplasms', 'Kidney Pelvis', 'Lipomatosis', 'Male', 'Middle Aged', 'Necrosis', 'Tomography, X-Ray', 'Ultrasonography', 'Urography'] | 675,899 | [['A10.165.114'], ['M01.060.116.100'], ['C23.300.070'], ['E01.171'], ['E01.354', 'N02.421.450.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['A05.810.453.537'], ['C1... | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glycemic variation and hypoglycemia in patients with well-controlled type 1 diabetes on a multiple daily insulin injection program with use of glargine and ultralente as basal insulin. | OBJECTIVE: To evaluate glycemic variation and hypoglycemia in patients with well-controlled type 1 diabetes receiving multiple daily insulin injections during glargine and Ultralente use as basal insulin in a clinical trial.METHODS: Twenty-two patients (12 men and 10 women; median age, 43 years), with a hemoglobin A1c ... | ['Adult', 'Aged', 'Blood Glucose', 'Cross-Over Studies', 'Diabetes Mellitus, Type 1', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemia', 'Hypoglycemic Agents', 'Insulin', 'Insulin Glargine', 'Insulin, Long-Acting', 'Male', 'Middle Aged', 'Single-Blind Method'] | 17,599,855 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Insertional mutagenesis affecting programmed cell death leads to thymic hyperplasia and altered thymopoiesis. | The mouse mutant Ft displays thymic hyperplasia and fused toes (Ft) of the forelimbs. Both phenotypic abnormalities are caused by transgene insertion in the D region of chromosome 8. While the forelimb defect is probably caused by developmentally dysregulated programmed cell death, the mechanism underlying thymic hyper... | ['Animals', 'Apoptosis', 'Cell Cycle', 'Cell Differentiation', 'Cell Movement', 'Hematopoiesis, Extramedullary', 'Homeostasis', 'Hyperplasia', 'Mice', 'Mice, Inbred C57BL', 'Mice, Mutant Strains', 'Mice, SCID', 'Mutagenesis, Insertional', 'Radiation Chimera', 'Stromal Cells', 'T-Lymphocytes', 'Thymus Gland'] | 8,598,454 | [['B01.050'], ['G04.146.954.035'], ['G04.144'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['G04.152.825.463', 'G09.188.343.463'], ['G07.410'], ['C23.550.444'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.150.900.649.313.99... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion: six-month results of the phase 3 COPERNICUS study. | OBJECTIVE: To assess the efficacy and safety of intravitreal vascular endothelial growth factor (VEGF) Trap-Eye in eyes with macular edema secondary to central retinal vein occlusion (CRVO).DESIGN: Multicenter, randomized, prospective, controlled trial.PARTICIPANTS: One hundred eighty-nine eyes with macular edema secon... | ['Aged', 'Angiogenesis Inhibitors', 'Double-Blind Method', 'Eye Pain', 'Female', 'Humans', 'Intravitreal Injections', 'Macular Edema', 'Male', 'Prospective Studies', 'Receptors, Vascular Endothelial Growth Factor', 'Recombinant Fusion Proteins', 'Retinal Vein Occlusion', 'Surveys and Questionnaires', 'Treatment Outcome... | 22,440,275 | [['M01.060.116.100'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C11.300.500', 'C23.888.307.625', 'C23.888.592.612.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.475.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PTEN protein expression in malignant pleural mesothelioma. | Malignant pleural mesothelioma is associated with poor prognosis and despite recent advances in chemotherapy, the median survival is still approximately 12 months. Loss of phosphatase and tensin homolog (PTEN) protein expression may lead to constitutive activation of AKT resulting in cell survival and proliferation. Sm... | ['Biomarkers, Tumor', 'Follow-Up Studies', 'Humans', 'Immunoenzyme Techniques', 'Mesothelioma', 'Neoplasms, Glandular and Epithelial', 'PTEN Phosphohydrolase', 'Pleural Neoplasms', 'Prognosis', 'Survival Rate'] | 23,242,608 | [['D23.101.140'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['C04.557.470.035.510', 'C04.557.470.660.510'], ['C04.557.470'], ['D08.811.277.352.650.850', 'D12.776.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Riluzole stimulates nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis in cultured mouse astrocytes. | Riluzole is an antiexcitotoxic agent used for the treatment of amyotrophic lateral sclerosis, and reported to have neuroprotective effects in animal models of Parkinson's disease, Huntington's disease and brain ischemia. We investigated the effects of riluzole on synthesis of nerve growth factor (NGF), brain-derived ne... | ['Animals', 'Astrocytes', 'Brain-Derived Neurotrophic Factor', 'Cells, Cultured', 'Glial Cell Line-Derived Neurotrophic Factor', 'Mice', 'Mice, Inbred ICR', 'Nerve Growth Factor', 'Nerve Growth Factors', 'Nerve Tissue Proteins', 'Neuroprotective Agents', 'Riluzole'] | 11,585,581 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['A11.251'], ['D12.644.276.860.381.500', 'D12.776.467.860.381.500', 'D12.776.631.600.381.500', 'D23.529.850.381.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.52... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Reconstruction of tibial exposure with local muscular flap, VSD and skin transplantation]. | OBJECTIVE: To investigate the treatment for tibial exposure wounds.METHODS: 39 patients with tibial exposure wounds were divided into three groups according to the exposure location (upper, medium and below). The local muscular flaps were designed to cover the tibial exposure, followed by skin grafts and VSD. VSD was r... | ['Humans', 'Lacerations', 'Skin', 'Skin Transplantation', 'Surgical Flaps', 'Tibia', 'Time Factors', 'Treatment Outcome', 'Wound Healing'] | 26,665,928 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.540'], ['A17.815'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['A10.850.710', 'E07.862.710'], ['A02.835.232.043.650.883'], ['G01.910.857'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['G16.762.891']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modern mosaic analysis in the zebrafish. | One of the most powerful tools used to gain insight into complex developmental processes is the analysis of mosaic embryos. A mosaic is defined as an organism that contains cells of more than one genotype, usually wild-type and mutant. It is the interplay between wild-type and mutant cells in the mosaic that reveals in... | ['Animals', 'Cell Differentiation', 'Cell Lineage', 'Cell Transplantation', 'Chimera', 'Embryo, Nonmammalian', 'Genetic Engineering', 'Mosaicism', 'Signal Transduction', 'Zebrafish', 'Zebrafish Proteins'] | 16,829,130 | [['B01.050'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['E02.095.147.500', 'E04.936.225'], ['B05.200'], ['A13.350', 'A16.331'], ['E05.393.420'], ['G05.365.590.175.595'], ['G02.111.820', 'G04.835'], ['B01.050.150.900.493.200.244.828'], ['D12.776.325.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of rat Ccnd1 gene by exendin-4 in pancreatic beta cell line INS-1: interaction of early growth response-1 with cis-regulatory element. | AIMS/HYPOTHESIS: The aim of this study was to investigate the effect of exendin-4 on the expression of cyclin D1 gene (Ccnd1), which is critical in regulating the progression of the cell cycle in INS-1 cells.MATERIALS AND METHODS: INS-1 cells were stimulated with exendin-4 (10 nmol/l). Transient transfection and lucife... | ['Animals', 'Base Sequence', 'Cell Division', 'Cell Line', 'Cyclin D', 'Cyclins', 'Exenatide', 'Gene Expression Regulation', 'Humans', 'Insulinoma', 'Islets of Langerhans', 'Molecular Sequence Data', 'Pancreatic Neoplasms', 'Peptides', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Regu... | 16,547,599 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D12.644.360.262.150', 'D12.776.167.218.150', 'D12.776.476.262.150'], ['D12.644.360.262', 'D12.776.167.218', 'D12.776.476.262'], ['D12.644.187', 'D20.888.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Vascular smooth muscle oxygen consumption is reversibly stimulated by sera from women with preeclampsia. | OBJECTIVE: Preeclampsia is a complication of pregnancy that causes maternal vasoconstriction and hypertension. The disease may progress to eclampsia, which is thought to be related to cerebral vasospasm. Although there is evidence for more than one circulating factor that causes endothelial cell dysfunction in preeclam... | ['Animals', 'Carotid Arteries', 'Female', 'Humans', 'Muscle, Smooth, Vascular', 'Oxygen Consumption', 'Pre-Eclampsia', 'Pregnancy', 'Swine'] | 9,855,592 | [['B01.050'], ['A07.015.114.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['G03.680'], ['C13.703.395.249'], ['G08.686.784.769'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Whipworm genome and dual-species transcriptome analyses provide molecular insights into an intimate host-parasite interaction. | Whipworms are common soil-transmitted helminths that cause debilitating chronic infections in man. These nematodes are only distantly related to Caenorhabditis elegans and have evolved to occupy an unusual niche, tunneling through epithelial cells of the large intestine. We report here the whole-genome sequences of the... | ['Animals', 'Gene Expression Profiling', 'Genome, Helminth', 'Host-Parasite Interactions', 'Humans', 'Intestines', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Phylogeny', 'Species Specificity', 'Th1 Cells', 'Trichuriasis', 'Trichuris'] | 24,929,830 | [['B01.050'], ['E05.393.332'], ['G05.360.340.337'], ['G16.527.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G16.824... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer. | This study explored decreased tumor suppressor microRNA (miRNA) plasma levels in pancreatic cancer (PCa) patients to clarify their potential as novel biomarkers and therapeutic targets. We used the microRNA array-based approach to select candidates by comparing plasma levels between PCa patients and healthy volunteers.... | ['Aged', 'Animals', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'Cell Proliferation', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Mice, SCID', 'MicroRNAs', 'Middle Aged', 'Neoplasm Staging', 'Neoplasm Transplantation', 'Pancreatic Neoplasms', 'Prognosis'] | 28,720,759 | [['M01.060.116.100'], ['B01.050'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['B01.050.150.900.649.313.992.635.505.500.550.780'], ['D13.150.650.319', 'D13.444.735.15... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Carcase composition of Taiwan simulated native chickens. | This study investigated the carcase composition of Taiwan simulated native chickens at different stages of growth. The results indicated that the carcases of male chickens exhibited significantly larger protein mass and water mass than those of females during weeks 7 to 20; as was the ash mass during weeks 8 to 20. How... | ['Animal Feed', 'Animals', 'Body Composition', 'Chickens', 'Energy Intake', 'Fats', 'Female', 'Male', 'Meat', 'Proteins', 'Random Allocation', 'Regression Analysis', 'Sex Characteristics', 'Taiwan', 'Water'] | 10,504,104 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240.340'], ['D10.212'], ['G07.203.300.600', 'J02.500.600'], ['D12.776'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.8... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Vitamin D can ameliorate chlorhexidine gluconate-induced peritoneal fibrosis and functional deterioration through the inhibition of epithelial-to-mesenchymal transition of mesothelial cells. | BACKGROUND: Peritoneal dialysis (PD) can induce fibrosis and functional alterations in PD patients' peritoneal membranes, due to long-term unphysiological dialysate exposure, partially occurring via triggering of epithelial-to-mesenchymal transition (EMT) in peritoneal mesothelial cells (MCs). Vitamin D can ameliorate ... | ['Animals', 'Cells, Cultured', 'Chlorhexidine', 'Dose-Response Relationship, Drug', 'Epithelial-Mesenchymal Transition', 'Epithelium', 'Humans', 'Male', 'Peritoneal Fibrosis', 'Rats', 'Rats, Sprague-Dawley', 'Treatment Outcome', 'Vitamin D'] | 26,495,304 | [['B01.050'], ['A11.251'], ['D02.078.370.141.100'], ['G07.690.773.875', 'G07.690.936.500'], ['G04.356.500'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.844.610', 'C23.550.355.625'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E01.789.800', 'N0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of water adsorption onto carbonaceous materials produced from food wastes. | The recycling of organic wastes has become very important and the development of technology for recycling organic wastes needs to sustain industrial development. In this study, techniques for producing carbonaceous materials from organic wastes are described and water adsorption is characterized. The organic wastes use... | ['Adsorption', 'Carbon', 'Conservation of Natural Resources', 'Food', 'Refuse Disposal', 'Water'] | 12,702,368 | [['G01.030', 'G02.020'], ['D01.268.150'], ['J01.256', 'N06.230.080'], ['G07.203.300', 'J02.500'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.900.600'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Association between duration of playing video games and bone mineral density in Chinese adolescents. | The aim of the study was to investigate the association between duration of playing video games and bone mineral density (BMD) in Chinese adolescents. Three hundred eighty-four Chinese adolescents aged 14-18 yr (148 males and 236 females) were analyzed. Anthropometric measurements were obtained using standard procedure... | ['Absorptiometry, Photon', 'Adolescent', 'Bone Density', 'Bone and Bones', 'China', 'Female', 'Humans', 'Male', 'Motor Activity', 'Pelvic Bones', 'Spine', 'Surveys and Questionnaires', 'Tibia', 'Time Factors', 'Video Games'] | 25,937,308 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.057'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['A02.835.232.043.825'], ['A02.835.232.834'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Rheumatoid lymphoedema. | Bilateral upper limb oedema due to lymphatic obstruction, is an uncommon complication of rheumatoid arthritis (R. A.). We report a case in which a 40 year old male with seropositive rheumatoid arthritis developed gross pitting oedema of the left arm. Lymphangiography showed lymphatic obstruction in both arms; within tw... | ['Adult', 'Arm', 'Arthritis, Rheumatoid', 'Humans', 'Lymphedema', 'Lymphography', 'Male'] | 6,926,809 | [['M01.060.116'], ['A01.378.800.075'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604.496'], ['E01.370.350.700.475']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Does computer tomography facilitate correct diagnosis of the cause of ureteral obstruction? (limitations and significance of CT)]. | The limitations of differentiation of retroperitoneal and pelvic paraureteral lesions causing ureteral obstruction are discussed in 84 cases using computerized tomography. The unspecific feature of a plate- and weblike connective tissue pattern in tumors, scar formation and inflammatory process is demonstrated | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pelvic Neoplasms', 'Retroperitoneal Neoplasms', 'Tomography, X-Ray Computed', 'Ureteral Obstruction'] | 6,467,811 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.699'], ['C04.588.033.731'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['C12.777.725.776', 'C13.351.968.725.776']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Central nervous system myelin deficit in rats exposed to 2,4-dichlorophenoxyacetic acid throughout lactation. | Our results show that 2,4-dichlorophenoxyacetic acid (2,4-D) exposure through mother's milk during the period of rapid myelination (from the 15th to the 25th postnatal days) results in a myelin deficit in the pup's brain and demonstrates the vulnerability of the developing central nervous system (CNS) to 2,4-D. After 1... | ['2,4-Dichlorophenoxyacetic Acid', 'Analysis of Variance', 'Animals', 'Animals, Suckling', 'Brain', 'Cholesterol', 'Cholesterol Esters', 'Fatty Acids, Nonesterified', 'Female', 'Herbicides', 'Lactation', 'Lipid Metabolism', 'Male', 'Maternal Exposure', 'Myelin Sheath', 'Neurotoxins', 'Phospholipids', 'Rats'] | 8,947,946 | [['D02.241.081.018.386.682.224', 'D02.241.511.316.682.149'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.050.293'], ['A08.186.211'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The immunogenic SigA enterotoxin of Shigella flexneri 2a binds to HEp-2 cells and induces fodrin redistribution in intoxicated epithelial cells. | BACKGROUND: We have previously shown that the enterotoxin SigA which resides on the she pathogenicity island (PAI) of S. flexneri 2a is an autonomously secreted serine protease capable of degrading casein. We have also demonstrated that SigA is cytopathic for HEp-2 cells and plays a role in the intestinal fluid accumul... | ['Antibody Formation', 'Bacterial Proteins', 'Carrier Proteins', 'Cell Line', 'Enterotoxins', 'Epithelial Cells', 'Humans', 'Microfilament Proteins', 'Protein Binding', 'Protein Transport', 'Shigella flexneri'] | 20,011,051 | [['G12.450.050.370.250'], ['D12.776.097'], ['D12.776.157'], ['A11.251.210'], ['D23.946.330'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.730', 'D12.776.220.525'], ['G02.111.679', 'G03.808'], ['G03.143.700'], ['B03.440.450.425.850.450', 'B03.660.250.150.730.210']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of albumin on the kinetics of ascorbate oxidation. | The fluorescence intensity of the fluorophore in dansyl piperidine-nitroxide is intramolecularly quenched by the nitroxyl fragment. Therefore, the oxidation of ascorbic acid by the fluorophore-nitroxide (FN) probe can be monitored by two independent methods: steady-state fluorescence and electron paramagnetic resonance... | ['Adsorption', 'Ascorbic Acid', 'Cyclic N-Oxides', 'Electron Spin Resonance Spectroscopy', 'Hydrogen-Ion Concentration', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Oxidation-Reduction', 'Serum Albumin, Bovine', 'Spectrometry, Fluorescence', 'Spin Labels', 'Static Electricity'] | 11,287,122 | [['G01.030', 'G02.020'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D03.661.243'], ['E05.196.867.519.274'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['G02.700', 'G03.295.531'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Five-year prospective follow-up report of the Astra tech standard dental implant in clinical treatment. | Between 1994 and 1999, 515 Astra standard implants were placed and documented prospectively in 107 patients. Of these implants, 364 were placed in original jawbone, 38 in areas augmented with local osteoplasty, and 113 in bone grafts from the iliac crest. The main indications for implantation were an atrophic edentulou... | ['Alveolar Bone Loss', 'Alveolar Ridge Augmentation', 'Atrophy', 'Bone Transplantation', 'Dental Arch', 'Dental Implantation, Endosseous', 'Dental Implants', 'Dental Prosthesis Design', 'Dental Restoration Failure', 'Follow-Up Studies', 'Humans', 'Jaw, Edentulous', 'Mandible', 'Maxilla', 'Osseointegration', 'Periodonti... | 11,516,003 | [['C05.116.264.150', 'C07.465.714.354.500'], ['E04.545.550.100', 'E06.645.550.100'], ['C23.300.070'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['A02.835.232.781.324.502.320', 'A14.521.320'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Visual outcome in children with juvenile idiopathic arthritis related uveitis. | PURPOSE: To determine the incidence and characteristics of uveitis in a cohort of patients with juvenile idiopathic arthritis (JIA) as well as the nature of treatment and the risk factors for visual loss.PATIENTS AND METHODS: Retrospective review of 52 patients with JIA, screened for uveitis between 1995 and 2005. The ... | ['Arthritis, Juvenile', 'Child', 'Child, Preschool', 'Comorbidity', 'Female', 'Humans', 'Male', 'Retrospective Studies', 'Risk Factors', 'Treatment Outcome', 'Uveitis', 'Visual Acuity'] | 16,903,513 | [['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Significance of infundibular obstruction following balloon valvuloplasty for valvar pulmonic stenosis. | This study was designed to define the prevalence and significance of infundibular obstruction following balloon pulmonary valvuloplasty. Thirteen of 62 children had infundibular gradients prior to valvuloplasty; five of these disappeared following balloon valvuloplasty. Five other children without pre-valvuloplasty inf... | ['Adolescent', 'Adult', 'Blood Pressure', 'Cardiac Catheterization', 'Catheterization', 'Child', 'Child, Preschool', 'Female', 'Heart Ventricles', 'Humans', 'Infant', 'Male', 'Pulmonary Valve Stenosis'] | 2,741,801 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E02.148', 'E05.157'], ['M01.060.406'], ['M01.060.406.448'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C14.280.484.716', 'C14.280.955.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
One building block, two different nanoporous self-assembled monolayers: a combined STM and Monte Carlo study. | With the use of a single building block, two nanoporous patterns with nearly equal packing density can be formed upon self-assembly at a liquid-solid interface. Moreover, the formation of both of these porous networks can be selectively and homogenously induced by changing external parameters like solvent, concentratio... | ['Computer Simulation', 'Crystallization', 'Materials Testing', 'Microscopy, Electron, Scanning Transmission', 'Models, Chemical', 'Models, Molecular', 'Models, Statistical', 'Monte Carlo Method', 'Nanostructures', 'Particle Size'] | 22,206,261 | [['L01.224.160'], ['E05.196.300', 'G02.171'], ['E05.570'], ['E01.370.350.515.402.580.480', 'E05.595.402.580.480'], ['E05.599.495'], ['E05.599.595'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['J... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Ectopia hepatica extrathoracica nuda associated with amelia and pulmonary agenesis. | A neonate with a constellation of unusual congenital deformities associated with pulmonary agenesis is reported. | ['Abnormalities, Multiple', 'Arm', 'Fatal Outcome', 'Hamartoma', 'Humans', 'Infant, Newborn', 'Liver', 'Lung', 'Male', 'Radiography', 'Thoracic Diseases'] | 10,415,290 | [['C16.131.077'], ['A01.378.800.075'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C04.445'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A03.620'], ['A04.411'], ['E01.370.350.700'], ['C08.846']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exploratory Validation of a Multidimensional Power Wheelchair Outcomes Toolkit. | OBJECTIVE: To evaluate the relation among the measures in a power wheelchair outcomes toolkit.DESIGN: We performed path analysis of cross-sectional data from self-report questionnaires and 1 objective measure.SETTING: Six sites.PARTICIPANTS: A convenience sample of power wheelchair users (N=128). Most (n=69; 53.9%) par... | ['Aged', 'Cross-Sectional Studies', 'Disabled Persons', 'Electric Power Supplies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mobility Limitation', 'Multiple Sclerosis', 'Outcome Assessment, Health Care', 'Physical Therapy Modalities', 'Reproducibility of Results', 'Self Concept', 'Self Efficacy', 'Social Participatio... | 26,403,685 | [['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.150'], ['E07.305.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.550'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['H01.770.644.145.431', 'N04.761.559.59... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Plant Phenology Supports the Multi-emergence Hypothesis for Ebola Spillover Events. | Ebola virus disease outbreaks in animals (including humans and great apes) start with sporadic host switches from unknown reservoir species. The factors leading to such spillover events are little explored. Filoviridae viruses have a wide range of natural hosts and are unstable once outside hosts. Spillover events, whi... | ['Animals', 'Climate Change', 'Disease Outbreaks', 'Disease Reservoirs', 'Disease Transmission, Infectious', 'Ebolavirus', 'Ecosystem', 'Hemorrhagic Fever, Ebola', 'Humans', 'Seasons'] | 29,134,435 | [['B01.050'], ['G16.500.175.374'], ['N06.850.290'], ['N06.850.520.203.250'], ['N06.850.335'], ['B04.820.480.937.300.200'], ['G16.500.275.157', 'N06.230.124'], ['C01.925.782.417.415', 'C01.925.782.580.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Determinants of drinking water quality in rural Nicaragua. | One hundred and fifty-three water samples from rural Nicaragua were examined for the presence of faecal coliforms during both wet and dry periods. A linear model was fitted by analysis of covariance with the logarithm of the faecal coliform count as the dependent variable. As expected, traditional water sources were gr... | ['Child', 'Diarrhea', 'Female', 'Housing', 'Humans', 'Nicaragua', 'Quality Control', 'Rain', 'Rural Health', 'Water Supply'] | 2,737,254 | [['M01.060.406'], ['C23.888.821.214'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.169.690'], ['J01.897.608'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['N... | ['Named Groups [M]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Protective effect of C-reactive protein against the lethality induced by Vibrio vulnificus lipopolysaccharide. | Vibrio vulnificus infection has attracted special interest because of its high mortality. A strong clinical association exists between hepatic dysfunction and increased morbidity and mortality from V. vulnificus infection. In this study, the effect of C-reactive protein (CRP), a typical hepatogenic acute phase protein,... | ['Animals', 'C-Reactive Protein', 'Female', 'Galactosamine', 'In Vitro Techniques', 'Injections, Intraperitoneal', 'Lipopolysaccharides', 'Liver', 'Mice', 'Mice, Inbred ICR', 'Survival Rate', 'Tumor Necrosis Factor-alpha', 'Vibrio'] | 10,888,350 | [['B01.050'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D09.067.342.356'], ['E05.481'], ['E02.319.267.530.490'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Malaria Transmission around the Memve'ele Hydroelectric Dam in South Cameroon: A Combined Retrospective and Prospective Study, 2000⁻2016. | Dam constructions are considered a great concern for public health. The current study aimed to investigate malaria transmission in the Nyabessan village around the Memve'ele dam in South Cameroon. Adult mosquitoes were captured by human landing catches in Nyabessan before and during dam construction in 2000-2006 and 20... | ['Animals', 'Anopheles', 'Cameroon', 'Female', 'Humans', 'Malaria', 'Mosquito Vectors', 'Plasmodium falciparum', 'Power Plants', 'Prospective Studies', 'Retrospective Studies'] | 31,075,820 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['Z01.058.290.100.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530', 'C01.920.875'], ['N06.850.335.188.100.500.500', 'N06.850.520.203.375.100.500.500'], ['B01.043.075.380.611.561'], ['J01.780', 'J03.540.680'], ['E05.318.372.... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein. | The sequence of a region of the HCMV genome transcribed during the immediate early (IE) transcriptional phase has been determined. Transcription analysis of this region at the junction between fragments HindIII Z and J has identified three moderately abundant mRNAs of 3.4, 1.7, and 1.65 kb. The 3.4-kb RNA is expressed ... | ['Amino Acid Sequence', 'Base Sequence', 'Cytomegalovirus', 'Genes', 'Genes, Viral', 'Membrane Glycoproteins', 'Molecular Sequence Data', 'Viral Proteins'] | 2,838,954 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B04.280.382.150.150'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['D12.776.395.550', 'D12.776.543.550'], ['L01.453.245.667'], ['D12.776.964']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intracranial irregularities beside hydrocephalus in H-Tx rats. | INTRODUCTION: It has been well documented that up to 70% of H-Tx rats' offspring suffer from severe hydrocephalus, which can be fatal if it remains untreated. Some offspring also have non-fatal moderate hydrocephalus allowing a normal life expectancy. The objective of this study was finding other morphological intracra... | ['Animals', 'Animals, Newborn', 'Brain', 'Cerebrospinal Fluid Shunts', 'Disease Models, Animal', 'Female', 'Functional Laterality', 'Hydrocephalus', 'Lateral Ventricles', 'Magnetic Resonance Imaging', 'Male', 'Rats'] | 19,812,933 | [['B01.050'], ['B01.050.050.282'], ['A08.186.211'], ['E04.035.188', 'E04.525.170'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['F02.830.297.425', 'G11.561.225.425'], ['C10.228.140.602'], ['A08.186.211.140.650'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic algorithm-assisted optimization of nanoporous TiO₂ for low-temperature processable photoanodes of dye-sensitized solar cells. | Genetic algorithm (GA), a promising optimization process in Heuristics, has proven to be a powerful tool in controlling the nanostructure of low-temperature processable photoanodes in dye-sensitized solar cells (DSSC). For photoanodes that are composed of various sizes of TiO₂ nanoparticles and multiwalled carbon nanot... | ['Algorithms', 'Cold Temperature', 'Coloring Agents', 'Electrodes', 'Models, Genetic', 'Nanostructures', 'Porosity', 'Solar Energy', 'Sunlight', 'Titanium'] | 21,207,976 | [['G17.035', 'L01.224.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D27.720.233'], ['E07.305.250'], ['E05.599.395.397'], ['J01.637.512'], ['G01.374.710'], ['G01.750.897', 'N06.230.132.644.500'], ['G01.358.500.505.650.836... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Optical Sectioning and High Resolution in Single-Slice Structured Illumination Microscopy by Thick Slice Blind-SIM Reconstruction. | The microscope image of a thick fluorescent sample taken at a given focal plane is plagued by out-of-focus fluorescence and diffraction limited resolution. In this work, we show that a single slice of Structured Illumination Microscopy (two or three beam SIM) data can be processed to provide an image exhibiting tight s... | ['Actins', 'Algorithms', 'Artifacts', 'Breast Neoplasms', 'Cell Line, Tumor', 'Female', 'Humans', 'Lighting', 'Microscopy, Fluorescence', 'Optical Imaging', 'Paxillin'] | 26,147,644 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G17.035', 'L01.224.050'], ['E05.047'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.230.150.410'], ['E01.370.350.515.458', 'E05.595.458'], ['E01.370.350.589', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Prognostic Significance of TYRO3 Receptor Tyrosine Kinase Expression in Gastric Cancer. | BACKGROUND: Despite improved treatment for gastric cancer (GC), the prognosis of advanced disease remains poor. Further investigation of the oncogenic sequence for GC is needed.MATERIALS AND METHODS: The expression of TYRO3 protein tyrosine kinase in five GC cell lines was confirmed using western blotting. TYRO3 knockd... | ['Aged', 'Biomarkers, Tumor', 'Carcinogenesis', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Disease Progression', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Middle Aged', 'Neoplasm Invasiveness', 'Prognosis', 'Proto-Oncogene Proteins c-akt', 'Receptor Protein-Tyrosine Kinases', 'Stom... | 32,988,883 | [['M01.060.116.100'], ['D23.101.140'], ['C04.697.098', 'C23.550.727.098'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C23.550.291.656'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.645', 'C23.550.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Elevation of plasma membrane permeability by laser irradiation of selectively bound nanoparticles. | Irradiation of nanoabsorbers with pico- and nanosecond laser pulses could result in thermal effects with a spatial confinement of less than 50 nm. Therefore absorbing nanoparticles could be used to create controlled cellular effects. We describe a combination of laser irradiation with nanoparticles, which changes the p... | ['Biopolymers', 'Cell Line, Tumor', 'Cell Membrane Permeability', 'Drug Delivery Systems', 'Fluoresceins', 'Humans', 'Lasers', 'Lymphoma', 'Nanostructures'] | 16,409,077 | [['D05.750.078', 'D25.720.099', 'J01.637.051.720.099'], ['A11.251.210.190', 'A11.251.860.180'], ['G03.143.335', 'G04.175'], ['E02.319.300'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490', 'E07.710.520'], ['C04.557.386', 'C15.604.515.569', ... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Continuous SSCF of AFEX™ pretreated corn stover for enhanced ethanol productivity using commercial enzymes and Saccharomyces cerevisiae 424A (LNH-ST). | High productivity processes are critical for commercial production of cellulosic ethanol. One high productivity process-continuous hydrolysis and fermentation-has been applied in corn ethanol industry. However, little research related to this process has been conducted on cellulosic ethanol production. Here, we report ... | ['Biofuels', 'Bioreactors', 'Biotechnology', 'Enzymes', 'Ethanol', 'Fermentation', 'Hydrolysis', 'Microbial Viability', 'Saccharomyces cerevisiae', 'Xylose', 'Zea mays'] | 23,192,401 | [['D20.147', 'N06.230.132.644.124'], ['E07.115', 'J01.897.120.115'], ['H01.158.550', 'J01.897.120'], ['D08.811'], ['D02.033.375'], ['G02.111.158.249', 'G03.191.249'], ['G02.380'], ['G06.580'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D09.947.875.627.867'], ['B01.650.940.800.575.912.250.822.966']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Nicotine potentiates the electrical field stimulation-evoked contraction of non-pregnant rabbit myometrium. | The women who smoke have lower fertility rates which might be due to harmful effects of nicotine on tubal function and menstrual cycle. Although the uterine contractility of the non-pregnant uterus plays an important role in the human reproduction process, the influence of nicotine on the contractile responses in uteru... | ['Analysis of Variance', 'Animals', 'Arginine', 'Atropine', 'Cadmium', 'Dose-Response Relationship, Drug', 'Electric Stimulation', 'Evoked Potentials', 'Female', 'Hexamethonium', 'Indomethacin', 'Isometric Contraction', 'Myometrium', 'Nicotine', 'Rabbits'] | 17,287,603 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['D01.268.556.137', 'D01.268.956.061', 'D01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Re-examination of the presence of alpha-lactalbumin in the epididymis of the rat. | Using an assay for alpha-lactalbumin in which galactosyltransferase activity was stabilized and a tissue phosphatase inhibitor was present, no evidence was found for alpha-lactalbumin-like activity in rat epididymal tissue, epididymal fluids or medium from cultured epididymal epithelial cells with either glucose or N-a... | ['Acetylglucosamine', 'Animals', 'Biological Assay', 'Epididymis', 'Female', 'Glucose', 'Lactalbumin', 'Lactation', 'Male', 'Mammary Glands, Animal', 'Pregnancy', 'Rats', 'Rats, Inbred Strains'] | 2,250,249 | [['D09.067.342.531.050'], ['B01.050'], ['E05.091'], ['A05.360.444.371'], ['D09.947.875.359.448'], ['D12.776.034.398', 'D12.776.256.159.750.816.250'], ['G08.686.523', 'G08.686.702.500'], ['A10.336.482', 'A13.589'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The endogenous cardiac sarcoplasmic reticulum Ca2+/calmodulin-dependent kinase is activated in response to beta-adrenergic stimulation and becomes Ca2+-independent in intact beating hearts. | We investigated the effects of beta-adrenergic stimulation on the activity of the endogenous cardiac sarcoplasmic reticulum Ca2+/calmodulin-dependent protein kinase (SRCaM kinase) in Langendorff-perfused rat hearts. We found that isoproterenol induced generation of autonomous (Ca2+-independent) SRCaM kinase activity to... | ['Adenosine Triphosphatases', 'Adrenergic beta-Agonists', 'Animals', 'Calcium', 'Calcium-Binding Proteins', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Enzyme Activation', 'Heart', 'Isoproterenol', 'Male', 'Myocardium', 'Phosphorylation', 'Rats', 'Rats, Wistar', 'Sarcoplasmic Reticulum'] | 9,202,132 | [['D08.811.277.040.025'], ['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.125'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['G02.111.263', 'G03.328'], ['A07.541'], ['D02.033.100.291.439', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lymphocytes infiltrating normal human lung and lung carcinomas rarely express gamma delta T cell antigen receptors. | It has been suggested that T lymphocytes expressing gamma delta T cell receptors (TCR) could play an important role in the defence of epithelia against infection and neoplastic transformation, but the potential for gamma delta T lymphocytes to serve these functions in human respiratory epithelium has received little at... | ['Adenocarcinoma', 'Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Female', 'Humans', 'Lung', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Receptors, Antigen, T-Cell, gamma-delta', 'T-Lymphocytes'] | 1,531,121 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['D12.776.543.750.705.816.824.830'], ['A11.118.637.555.567.569', 'A15.... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Measuring health anxiety: moving past the dichotomous response option of the original Whiteley Index. | The Whiteley Index [WI; Pilowsky, I. (1967). Dimensions of hypochondriasis. British Journal of Psychiatry, 113, 89-93] is a widely used self-report measure of health anxiety, hypochondriasis, and illness phobia; however, the factor structure of the WI has proven unstable. Moreover, factorial investigations of the WI pe... | ['Adolescent', 'Adult', 'Anxiety', 'Attitude to Health', 'Culture', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Hypochondriasis', 'Male', 'Middle Aged', 'Personality Inventory', 'Psychometrics', 'Reproducibility of Results', 'Young Adult'] | 19,560,314 | [['M01.060.057'], ['M01.060.116'], ['F01.470.132'], ['F01.100.150', 'N05.300.150'], ['I01.076.201.450', 'I01.880.853.100'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.875.450'], ['M01.060.116.630'], ['F04.711.647.513'], ['F04.711.780'], ['E0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Unpredictable anaphylactic reaction to protamine sulfate. | Anaphylactic reactions to protamine administration often can be predicted by the presence of patient risk factors. In the case described, an anaphylactic reaction to protamine occurred in a patient without identifiable risk factors. A history of prior protamine exposure, fish allergy, or vasectomy suggests patients may... | ['Anaphylaxis', 'Anesthesia', 'Aortic Valve', 'Humans', 'Male', 'Middle Aged', 'Protamines', 'Risk Factors'] | 3,366,060 | [['C20.543.480.099'], ['E03.155'], ['A07.541.510.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.660.750', 'D12.776.664.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pediatric femur fractures, epidemiology and treatment]. | BACKGROUND/AIM: Femur fractures in children most often occur as a consequence of traffic accidents, during play and sport activities, and due to different pathological states. Diagnosis is rather simple and it includes physical and radiographical examination. Femur fractures treatment in children can be operative and u... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Femoral Fractures', 'Humans', 'Infant', 'Male'] | 21,425,612 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C26.404.061', 'C26.558.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Role of á1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal symptoms. | ISSUE: The low incidence of extrapyramidal side effects associated with the atypical antipsychotic iloperidone may be linked to its unique binding profile of high affinity antagonism of both á1 adrenergic receptors and serotonin 2A receptors. | ['Adrenergic alpha-1 Receptor Antagonists', 'Animals', 'Basal Ganglia Diseases', 'Corpus Striatum', 'Dopamine', 'Humans', 'Isoxazoles', 'Piperidines', 'Serotonin 5-HT2 Receptor Antagonists'] | 24,300,463 | [['D27.505.519.625.050.200.100.100', 'D27.505.696.577.050.200.100.100'], ['B01.050'], ['C10.228.140.079'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.385'], ['D03.383.621'], ['D27.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interplay of the Organic Cation Transporters OCT1 and OCT2 with the Apically Localized Export Protein MATE1 for the Polarized Transport of Trospium. | The anticholinergic drug trospium is secreted into urine and, to a smaller extent, into bile. Chemically, it is an organic cation, and it is a substrate of the uptake transporters OCT1 and OCT2 as well as for the export proteins MATE1 and MATE2-K as determined in uptake studies using HEK293 cells. So far, neither MATE-... | ['Animals', 'Benzilates', 'Biological Transport', 'Cell Line', 'Dogs', 'HEK293 Cells', 'Humans', 'Muscarinic Antagonists', 'Nortropanes', 'Organic Cation Transport Proteins', 'Organic Cation Transporter 1', 'Organic Cation Transporter 2'] | 30,656,943 | [['B01.050'], ['D02.241.223.601.238.306', 'D02.241.511.085'], ['G03.143'], ['A11.251.210'], ['B01.050.150.900.649.313.750.250.216.200'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.625.120.200.500', 'D27.505.696.577.120.200.500'], ['D02.145.074.722.744', 'D03.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age at menarche in relation to anthropometric characteristics, competition level and boat category in elite junior rowers. | BACKGROUND: Within the context of the effects of training for sports on growth and maturation, there is very little menarcheal data for elite rowing athletes. Knowledge of the relationship of the maturational status with training level, different boat categories, and somatic features of the athletes will clarify the as... | ['Adolescent', 'Body Composition', 'Body Constitution', 'Case-Control Studies', 'Female', 'Humans', 'Menarche', 'Physical Education and Training', 'Retrospective Studies', 'Sports', 'Surveys and Questionnaires'] | 12,637,191 | [['M01.060.057'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115', 'G07.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.760.410', 'G08.686.841.374.410'], ['I02.233.543'], ['E05.318.372.500.500.500', 'E05.318.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Juvenile rat and pediatric trazodone studies: how to gain extra sensitivity to overcome bioanalytical challenges. | AIM: Trazodone (TZD) is used for the treatment of depression in adults and, off-label, as a sleep medication in adult and pediatric populations. The off-label use is well documented, however further clinical studies are needed to confirm its efficacy and safety for the treatment of sleep disorders. In this scenario, we... | ['Animals', 'Anti-Anxiety Agents', 'Blood Specimen Collection', 'Calibration', 'Capillaries', 'Chromatography, Liquid', 'Dose-Response Relationship, Drug', 'Female', 'Male', 'Rats', 'Reference Standards', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tandem Mass Spectrometry', 'Toxicokinetics', 'Trazodo... | 30,525,928 | [['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['E05.978.155'], ['A07.015.461.165'], ['E05.196.181.400'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.978.80... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Computed tomography (CT) in the selection of treatment for root-filled maxillary molars with apical periodontitis. | OBJECTIVES: The aims of this study were to evaluate whether the use of CT facilitates agreement among endodontists in selecting treatments for root-filled maxillary molars with apical periodontitis and to assess the efficacy of CT in choosing a treatment for such teeth.METHODS: 39 root-filled maxillary molars from 34 p... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Maxilla', 'Middle Aged', 'Molar', 'Periapical Periodontitis', 'Tomography, X-Ray Computed', 'Young Adult'] | 26,985,980 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['M01.060.116.630'], ['A14.549.167.860.525'], ['C07.320.830.700', 'C07.465.714.306.700', 'C07.465.714.533.487'], ['E01.370.350.350.810', 'E01.370.350.600.350.7... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Brain death confirmation: comparison of computed tomographic angiography with nuclear medicine perfusion scan. | INTRODUCTION: : Brain death is a difficult diagnosis to make, relying primarily on clinical examination. Ancillary tests are used when confounders exist. Nuclear medicine perfusion test (NMPT) is currently the preferred test for confirming brain death. Computed tomographic angiography (CTA) may be an alternative test t... | ['Adult', 'Brain Death', 'Brain Injuries', 'Cerebral Angiography', 'Cerebrovascular Circulation', 'False Positive Reactions', 'Humans', 'Perfusion Imaging', 'Predictive Value of Tests', 'Prospective Studies', 'Tomography, X-Ray Computed'] | 20,220,416 | [['M01.060.116'], ['C10.228.140.151', 'C10.597.606.358.800.200.100', 'C23.550.260.159'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['G09.330.100.159'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Two novel treatments to reduce overeating in overweight children: a randomized controlled trial. | OBJECTIVE: Our purpose in this study was to examine 2 treatments targeted at reducing eating in the absence of hunger in overweight and obese children.METHOD: Thirty-six overweight and obese 8- to 12-year-old children (58% female; mean age = 10.3 years, SD = 1.3), with high scores on eating in the absence of hunger, an... | ['Behavior Therapy', 'Bulimia', 'Child', 'Feeding Behavior', 'Female', 'Humans', 'Hyperphagia', 'Male', 'Overweight', 'Surveys and Questionnaires', 'Treatment Outcome'] | 22,122,291 | [['F04.754.137'], ['C23.888.821.645.500'], ['M01.060.406'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.821.645'], ['C23.888.144.699', 'E01.370.600.115.100.160.120.699', 'G07.100.100.160.120.699'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The measuring and observation tool in sports. | The Measuring and Observation Tool in Sports (MOTS) has been designed to facilitate the systematic observation of sports. It is a user-friendly tool developed to help researchers observe, codify, register, and analyze any situation that occurs in a natural or habitual context in which behaviors are spontaneous. Users c... | ['Electronic Data Processing', 'Humans', 'Observation', 'Software', 'Sports'] | 18,697,686 | [['L01.224.085'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.249'], ['L01.224.900'], ['I03.450.642.845']] | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
[Assessment of pure isolated mitral valve insufficiency by Doppler echocardiography]. | Taking 33 patients having pure MI as a material, the authors find a correlation between regurgitation fraction obtained by calculation of outputs estimated by Touch's method and angiographic values. There is a statistically significant differences (P < 0.001) between regurgitation fraction of grade I to II and grade II... | ['Adolescent', 'Adult', 'Diagnosis, Differential', 'Echocardiography, Doppler', 'Female', 'Humans', 'Male', 'Mitral Valve Insufficiency', 'Reference Values', 'Statistics as Topic'] | 11,414,055 | [['M01.060.057'], ['M01.060.116'], ['E01.171'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.484.461'], ['E05.978.810'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Population genetic study of the STR loci (HUMCSF1PO, HUMTPOX, HUMTHO1, HUMLPL, HUMF13A01, HUMF13B, HSFESFPS and HUMVWA) in North Indians. | BACKGROUND: Highly polymorphic genetic markers like short tandem repeats (STRs) have been used successfully in disease analysis and studies of human evolution and population genetic diversity. However, DNA-based population genetic studies of Indian populations are limited.SUBJECTS AND METHODS: To enlarge our understand... | ['DNA Fingerprinting', 'Genetic Markers', 'Genetic Variation', 'Genetics, Population', 'Humans', 'India', 'Tandem Repeat Sequences'] | 12,573,084 | [['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['D23.101.387', 'G05.695.450'], ['G05.365'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['G02.111.570.080.708.800', 'G05.360.080.708.800', 'G05.360.340.024.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Identification of a human serum albumin species associated with familial dysalbuminemic hyperthyroxinemia. | Familial dysalbuminemic hyperthyroxinemia (FDH) is a form of euthyroid hyperthyroxinemia that is due to an increased affinity of serum albumin for T4. Unlike the many physiologically neutral alloalbumins that have been identified by serum electrophoresis, FDH variants have not been reproducibly resolved. In the present... | ['Detergents', 'Electrophoresis, Polyacrylamide Gel', 'Hispanic Americans', 'Humans', 'Hyperthyroxinemia', 'Isoelectric Focusing', 'Octoxynol', 'Polyethylene Glycols', 'Reference Values', 'Serum Albumin', 'Urea'] | 7,852,505 | [['D27.720.877.265', 'J01.516.381'], ['E05.196.401.402', 'E05.301.300.319'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.410'], ['E05.196.401.663', 'E05.301.300.663'], ['D02.033.455.250.700.660', 'D05.750.741.610', 'D25.720.741.610', 'J01.637.051.720.741.610'], ['D02.033.455.250.700'... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Lung cancer following chemotherapy and radiotherapy for Hodgkin's disease. | BACKGROUND: Lung cancer is a frequent cause of death in patients cured of Hodgkin's disease, but the contributions of chemotherapy, radiotherapy, and smoking are not well described. We quantified the risk of treatment-associated lung cancer, taking into account tobacco use.METHODS: Within a population-based cohort of 1... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Agents', 'Case-Control Studies', 'Child', 'Disease-Free Survival', 'Dose-Response Relationship, Drug', 'Dose-Response Relationship, Radiation', 'Female', 'Hodgkin Disease', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasms, Second Primary', 'Radiotherapy', 'Ri... | 11,830,608 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.99... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of endothelium-dependent and -independent vasomotor response after abluminal biodegradable polymer biolimus-eluting stent and persistent polymer everolimus-eluting stent implantation (COMPARE-IT). | BACKGROUND: Drug-eluting stents (DES) have been associated with local endothelial dysfunction in the segments proximal and distal to the stent (peristent segments) and increased thrombotic risk in long term follow-up. Little data exists on endothelial function post-implantation of new DES with biodegradable polymer. Th... | ['Absorbable Implants', 'Aged', 'Coronary Artery Disease', 'Drug-Eluting Stents', 'Endothelium, Vascular', 'Everolimus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polymers', 'Prospective Studies', 'Radiography', 'Single-Blind Method', 'Vasoconstriction', 'Vasodilation', 'Vasomotor System'] | 26,440,470 | [['E07.695.025'], ['M01.060.116.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E07.695.750.500'], ['A07.015.700.500', 'A10.272.491.355'], ['D02.540.505.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.318.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
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