Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Disease-based mortality after percutaneous endoscopic gastrostomy: utility of the enterprise data warehouse. | BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) remains a mainstay of enteral access. Thirty-day mortality for PEG has ranged from 16 to 43 %. This study aims to discern patient groups that demonstrate limited survival after PEG placement. The Enterprise Data Warehouse (EDW) concept allows an efficient means of i... | ['Comorbidity', 'Diabetes Mellitus', 'Enteral Nutrition', 'Female', 'Follow-Up Studies', 'Gastrostomy', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Pulmonary Disease, Chronic Obstructive', 'Risk Factors', 'Stroke', 'Survival Analysis', 'Survival Rate'] | 23,836,125 | [['N05.715.350.225', 'N06.850.490.687'], ['C18.452.394.750', 'C19.246'], ['E02.421.360', 'E02.642.500.360'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.496', 'E04.579.408'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], [... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation and Characterization of IgM and IgY Antibodies from Plasma of Magellanic Penguins (Spheniscus magellanicus). | Infectious diseases such as aspergillosis, avian malaria, and viral infections are significant threats to the conservation of penguins, leading to morbidity and mortality of these birds both in captivity and in the wild. The immune response to such infectious diseases is dependent on different mechanisms mediated by ce... | ['Animals', 'Immunoglobulin M', 'Immunoglobulins', 'Spheniscidae'] | 26,292,539 | [['B01.050'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.377.715.548.114.619.574'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['B01.050.150.900.248.860']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CesH Represses Cereulide Synthesis as an Alpha/Beta Fold Hydrolase in Bacillus cereus | Cereulide is notorious as a heat-stable emetic toxin produced by Bacillus cereus and glucose is supposed to be an ingredient supporting its formation. This study showed that glucose addition benefited on cell growth and the early transcription of genes involved in substrate accumulation and toxin synthesis, but it play... | ['Bacillus cereus', 'Bacterial Proteins', 'Depsipeptides', 'Glucose', 'Hydrolases'] | 31,010,094 | [['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218.252'], ['D12.776.097'], ['D04.345.566.297', 'D12.644.641.297'], ['D09.947.875.359.448'], ['D08.811.277']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Which difficulties do GPs experience in consultations with patients with unexplained symptoms: a qualitative study. | BACKGROUND: Many general practitioners (GPs) struggle with the communication with patients with medically unexplained symptoms (MUS). This study aims to identify GPs' difficulties in communication during MUS consultations.METHODS: We video-recorded consultations and asked GPs immediately after the consultation whether ... | ['Communication', 'Female', 'General Practitioners', 'Humans', 'Interviews as Topic', 'Male', 'Medically Unexplained Symptoms', 'Middle Aged', 'Physician-Patient Relations', 'Qualitative Research'] | 31,884,966 | [['F01.145.209', 'L01.143'], ['M01.526.485.810.485', 'N02.360.810.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['C23.888.541'], ['M01.060.116.630'], ['F01.829.401.650.675', 'N05.300.660.625'], ['H01.770.644.241.850']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Prevalence of disabilities and associated health conditions among adults--United States, 1999. | In the United States, the number of persons reporting disabling conditions increased from 49 million during 1991-1992 to 54 million during 1994-1995. During 1996, direct medical costs for persons with disability were $260 billion. Surveillance of disability prevalence and associated health conditions is useful in setti... | ['Activities of Daily Living', 'Adult', 'Arthritis', 'Cardiovascular Diseases', 'Cost of Illness', 'Disabled Persons', 'Female', 'Health Planning', 'Humans', 'Male', 'Prevalence', 'Spinal Diseases', 'United States'] | 11,393,491 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['C05.550.114'], ['C14'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['M01.150'], ['N03.349', 'N03.706.615.302'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Improving immunization rates: initial results from a team-based, systems change approach. | OBJECTIVE: The American College of Physicians (ACP) developed a quality improvement (QI) program to address deficiencies in immunization rates, primarily for influenza, and determine the program's impact on adult immunization.DESIGN: An interventional study using a pre-post design. Three cohorts of physician practices ... | ['Aged', 'Cohort Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Promotion', 'Humans', 'Influenza Vaccines', 'Male', 'Middle Aged', 'Quality of Health Care', 'Vaccination'] | 18,539,978 | [['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['F01.100.150.500', 'N05.300.150.410'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['M01.060.116.630'], ['N04.761', 'N05.715'], ['E02.095.465.42... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Mitochondrial genomes of the green macroalga Ulva pertusa (Ulvophyceae, Chlorophyta): novel insights into the evolution of mitogenomes in the Ulvophyceae. | To further understand the trends in the evolution of mitochondrial genomes (mitogenomes or mtDNAs) in the Ulvophyceae, the mitogenomes of two separate thalli of Ulva pertusa were sequenced. Two U. pertusa mitogenomes (Up1 and Up2) were 69,333 bp and 64,602 bp in length. These mitogenomes shared two ribosomal RNAs (rRNA... | ['China', 'Chromosome Mapping', 'DNA, Mitochondrial', 'Evolution, Molecular', 'Genome, Mitochondrial', 'Genome, Plant', 'Ulva'] | 28,677,163 | [['Z01.252.474.164'], ['E05.393.183'], ['D13.444.308.283.225'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.360'], ['G05.360.340.365'], ['B01.650.940.150.900']] | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Design dependent loss of telemetry: uplink telemetry hold. | Bidirectional telemetry in cardiac pacing is the ability of the programmer to communicate with the pacemaker and vice versa. It is an essential capability if one is to interrogate the pacemaker as to its programmed parameters and to access the diagnostic capabilities incorporated in the present generation pacemakers. P... | ['Equipment Design', 'Equipment Failure', 'Heart Block', 'Humans', 'Male', 'Pacemaker, Artificial', 'Software', 'Telemetry'] | 2,471,168 | [['E05.320'], ['E05.325'], ['C14.280.067.558', 'C14.280.123.500', 'C23.550.073.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.750'], ['L01.224.900'], ['E01.370.520.750', 'E05.925', 'L01.178.847.675']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Exploring selectivity requirements for COX-2 versus COX-1 binding of 3,4-diaryloxazolones using E-state index. | Considering the importance of developing selective COX-2 inhibitors, the present paper explores selectivity requirements for COX-2 versus COX-1 binding of 3,4-diaryloxazolones using electrotopological state (E-state) index. The study also shows the utility of E-state index in developing statistically acceptable model h... | ['Chemical Phenomena', 'Chemistry, Physical', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Cyclooxygenase Inhibitors', 'Isoenzymes', 'Oxazolone', 'Prostaglandin-Endoperoxide Synthases', 'Structure-Activity Relationship'] | 14,552,773 | [['G02'], ['H01.181.529'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.03... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Persistent Mycobacterium tuberculosis | The ability of Mycobacterium tuberculosis (Mtb) to persist in its host is central to the pathogenesis of tuberculosis, yet the underlying mechanisms remain incompletely defined. PerM, an integral membrane protein, is required for persistence of Mtb in mice. Here, we show that perM deletion caused a cell division defect... | ['Animals', 'Bacterial Proteins', 'Cell Cycle Proteins', 'Cell Division', 'Disease Models, Animal', 'Female', 'Gene Expression Regulation, Bacterial', 'Gene Knockout Techniques', 'Lung', 'Membrane Proteins', 'Mice', 'Mice, Inbred C57BL', 'Mycobacterium tuberculosis', 'Phenotype', 'Tuberculosis'] | 31,751,212 | [['B01.050'], ['D12.776.097'], ['D12.776.167'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.308.300'], ['E05.393.335.750'], ['A04.411'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
INCREASING DIVERSITY IN OUR SCHOOLS OF NURSING. | This article will review one school's quest to address the multi-level social, historical, environmental and structural determinants faced by under-represented ethnic minorities (UREM) and disadvantaged background (DB) students as they seek entrance into a nursing program. Nursing Network Careers and Technology (NN-CAT... | ['Career Choice', 'Cultural Diversity', 'Curriculum', 'Education, Nursing, Baccalaureate', 'Educational Status', 'Humans', 'Minority Groups', 'North Carolina', 'Schools, Nursing'] | 27,439,229 | [['F02.463.785.373.346.400'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['I02.158'], ['I02.358.462.316'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.853.300'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['I02.783.495.623']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[International cooperation in combatting illicit drugs in Mozambique]. | Countries from Southern Africa have formed a Development Community (SADC) to stimulate common actions in several areas, among them illicit drugs combat. In this context, the goal of this qualitative study was to identify information and perception about the cooperation set up between Mozambique and other SADC members i... | ['Africa, Southern', 'Humans', 'Illicit Drugs', 'International Cooperation', 'Mozambique', 'Substance-Related Disorders'] | 21,739,058 | [['Z01.058.290.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['I01.615.500'], ['Z01.058.290.175.545'], ['C25.775', 'F03.900']] | ['Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Molecular properties of a novel, hydrophilic cation-binding protein associated with the plasma membrane. | A new type of protein was found in Arabidopsis thaliana, PCaP1, which is rich in glutamate and lysine residues. The protein bound (45)Ca(2+) even in the presence of a high concentration of Mg(2+). Real-time polymerase chain reaction and histochemical analysis of promoter-beta-glucuronidase fusions revealed that PCaP1 w... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'Calcium-Binding Proteins', 'Carrier Proteins', 'Cations', 'Cell Membrane', 'Flowers', 'Gene Expression Regulation, Plant', 'Molecular Sequence Data', 'Plant Leaves', 'Plant Roots', 'Plant Shoots', 'Plant Stems'] | 17,264,065 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D12.776.157.125'], ['D12.776.157'], ['D01.248.497.300'], ['A11.284.149'], ['A18.024.249.500'], ['G05.308.375'], ['L01.453.245.667'], ['A18.024.812'], ['A18.400'], ['A18.024.875'], ['A18.024.937']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Multiple regulation of adenylyl cyclase activity by G-protein coupled receptors in human foetal lung fibroblasts. | The pharmacological profile of adenylyl cyclase activity was analysed in WI-38 human foetal lung fibroblasts. Among various agents that act through G-protein coupled receptors, only the beta-adrenergic agonist isoproterenol stimulated and the tetradecapeptide somatostatin (SRIF, sst) inhibited the enzyme activity. The ... | ['Adenylyl Cyclases', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'DNA, Complementary', 'Fetus', 'Fibroblasts', 'GTP-Binding Proteins', 'Humans', 'Isoproterenol', 'Kinetics', 'Lung', 'Receptors, Somatostatin', 'Reverse Transcriptase Polymerase Chain Reaction', 'Somatostatin'] | 11,062,332 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['A16.378'], ['A11.329.228'], ['D08.811.277.040.330.300', 'D12.776.157.32... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mode of action of antitumour antibiotics. spectrophotometric studies on the interaction of chromomycin A3 with DNA and chromatin of normal and neoplastic tissue. | The binding of chromomycin A3, an antitumour antibiotic, to various DNA and chromatin isolated from mouse and rat liver, mouse fibrosarcoma and Yoshida ascites sarcoma cells was studied spectrophotometrically at 29 degrees C in 10-2 M Tris-HCl buffer, pH 8.0, containing small amounts of MgCl2 (4.5-10-5--25-10-5 M). An ... | ['Animals', 'Binding Sites', 'Chromatin', 'Chromomycins', 'DNA', 'DNA, Neoplasm', 'Fibrosarcoma', 'Kinetics', 'Liver', 'Magnesium', 'Mice', 'Rats', 'Sarcoma, Yoshida', 'Spectrophotometry'] | 1,125,225 | [['B01.050'], ['G02.111.570.120'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D09.408.210'], ['D13.444.308'], ['D13.444.308.425'], ['C04.557.450.565.590.350', 'C04.557.450.795.350'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First report of human anisakidosis in Australia. | We present the first human case of anisakidosis acquired from eating locally caught fish in Australia. A 41-year-old woman experienced gastrointestinal pain, vomiting and diarrhoea of increasing severity over 3 weeks. All symptoms resolved spontaneously after a worm was passed in her faeces. Microscopic examination sho... | ['Adult', 'Animals', 'Anisakiasis', 'Anisakis', 'Female', 'Humans', 'Larva', 'Seafood'] | 21,401,462 | [['M01.060.116'], ['B01.050'], ['C01.610.335.508.700.100.060', 'C01.610.432.060', 'C06.405.469.452.060'], ['B01.050.500.500.294.400.500.100.075'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G07.203.300.600.875', 'J02.500.600.875']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Parity-related molecular signatures and breast cancer subtypes by estrogen receptor status. | INTRODUCTION: Relationships of parity with breast cancer risk are complex. Parity is associated with decreased risk of postmenopausal hormone receptor-positive breast tumors, but may increase risk for basal-like breast cancers and early-onset tumors. Characterizing parity-related gene expression patterns in normal brea... | ['Adolescent', 'Adult', 'Aged', 'Breast Neoplasms', 'Case-Control Studies', 'Cluster Analysis', 'Female', 'Gene Expression Profiling', 'Humans', 'Middle Aged', 'Odds Ratio', 'Parity', 'Pregnancy', 'Receptors, Estrogen', 'Risk Factors', 'Transcriptome', 'Young Adult'] | 25,005,139 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MiR-7-5p is frequently downregulated in glioblastoma microvasculature and inhibits vascular endothelial cell proliferation by targeting RAF1. | The aberrant expression of microRNAs (miRNAs) is always associated with tumor development and progression. Microvascular proliferation is one of the unique pathologic features of glioblastoma (GBM) . In this study, the microvasculature from GBM or normal brain tissue derived from neurosurgeries was purified and total R... | ['Adult', 'Aged', 'Brain Neoplasms', 'Cell Proliferation', 'Down-Regulation', 'Endothelial Cells', 'Female', 'Gene Expression Regulation, Neoplastic', 'Genes, Tumor Suppressor', 'Glioblastoma', 'Humans', 'Male', 'MicroRNAs', 'Microvessels', 'Middle Aged', 'Oligonucleotide Array Sequence Analysis', 'Proto-Oncogene Prote... | 25,027,403 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A11.436.275'], ['G05.308.370'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['C04.557.465.625.600.380.080... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Processing order in dual-task situations: The "first-come, first-served" principle and the impact of task order instructions. | When two overlapping tasks are processed, they hit a bottleneck at a central processing stage that prevents simultaneous processing of the two tasks. Thus far, however, the factors determining the processing order of the tasks at the bottleneck are unknown. The present study was designed to (re)investigate whether the ... | ['Adult', 'Auditory Perception', 'Female', 'Humans', 'Male', 'Psychomotor Performance', 'Reaction Time', 'Refractory Period, Psychological', 'Visual Perception', 'Young Adult'] | 29,978,280 | [['M01.060.116'], ['F02.463.593.071', 'G07.888.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['E05.796.817.559', 'F02.830.650.400', 'F04.669.817.559'], ['F02.463.593.932'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Experience in toxicological monitoring in Moscow]. | A technology for the toxicological monitoring of chemical poisoning cases in Moscow is described. Its results over 2002-2006 are presented. The distribution of poisonings by causes, gender, and age, pattern, and occurrence circumstances is analyzed. A number of difficulties arising from the filling toxicological monito... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Environmental Monitoring', 'Epidemiological Monitoring', 'Female', 'Humans', 'Incidence', 'Infant', 'Male', 'Moscow', 'Poisoning', 'Retrospective Studies', 'Urban Population', 'Young Adult'] | 20,135,873 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.318.375', 'N06.850.520.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M0... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Neuropeptide Y directly affects ovarian cell proliferation and apoptosis. | The effects of neuropeptide Y (NPY; 0, 10, 100 and 1000 ng/mL) on the expression of PCNA, bax and p53 were examined by immunocytochemistry in porcine luteinized granulosa cells. NPY inhibited proliferation as well as promoted apoptosis and accumulation of p53 in the cells. This is the first report to demonstrate the di... | ['Animals', 'Apoptosis', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Female', 'Gene Expression Regulation', 'Granulosa Cells', 'Neuropeptide Y', 'Proliferating Cell Nuclear Antigen', 'Swine', 'Tumor Suppressor Protein p53', 'bcl-2-Associated X Protein'] | 26,679,167 | [['B01.050'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812', 'A11.436.329'], ['D12.644.400.500', 'D12.776.631.650.500'], ['D12.776.660.740', 'D23.050.290.750', 'D23.101.140.600'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Poorly-differentiated thyroid carcinoma: morphological verification and differential diagnosis]. | Poorly-differentiated thyroid carcinoma is a stage in the development of anaplastic carcinoma from well-differentiated neoplastic transformation of follicular epithelium. Such tumors differ with respect to histological pattern and age. For instance, patients, aged 50 and more, revealed great nodular size (50-70 mm), ma... | ['Adolescent', 'Adult', 'Aged', 'Carcinoma', 'Cell Transformation, Neoplastic', 'Child', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mitotic Index', 'Neoplasm Invasiveness', 'Retrospective Studies', 'Thyroid Neoplasms'] | 16,715,703 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200'], ['C04.697.098.500', 'C23.550.727.098.500'], ['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.225.500.385.500', 'E05.200.500.385.500', 'E05.242.385.500'], ['C04.697.645', 'C23.550.727... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenovirus DNA synthesis in vitro is inhibited by the virus-coded major core protein. | The effects of the adenovirus type 2 (Ad2) structural proteins on Ad DNA synthesis in vitro have been examined. Both of the viral core proteins, polypeptides V and VII were shown to inhibit Ad2 DNA synthesis in vitro; however, only the major core protein, polypeptide VII, inhibited DNA synthesis at a ratio of protein t... | ['Adenoviridae', 'DNA Replication', 'Electrophoresis, Polyacrylamide Gel', 'HeLa Cells', 'Humans', 'Micrococcal Nuclease', 'Thymine Nucleotides', 'Viral Core Proteins', 'Viral Structural Proteins', 'Virion'] | 3,962,184 | [['B04.280.030'], ['G02.111.225', 'G05.226'], ['E05.196.401.402', 'E05.301.300.319'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.352.335.350.500', 'D08.811.277.352.355.325.500', 'D08.811.277.352.355.350.500', 'D08.811.277.352.700.350.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum antibodies to capsular polysaccharide vaccine of group A Neissera meningitidis followed for three years in infants and children. | The persistence of antibodies to the capsular polysaccharide of group A Neissera meningitidis was studied in 2,030 persons vaccinated at the age of 10 weeks to 19 years and followed for three years. Both the initial antibody response and the persistence of elevated serum titers of antibody were markedly age-dependent. ... | ['Adolescent', 'Adult', 'Antibody Formation', 'Antigens, Bacterial', 'Antigens, Surface', 'Bacterial Vaccines', 'Child', 'Child, Preschool', 'Finland', 'Humans', 'Immunization, Secondary', 'Infant', 'Meningitis, Meningococcal', 'Neisseria meningitidis', 'Polysaccharides, Bacterial'] | 6,780,634 | [['M01.060.057'], ['M01.060.116'], ['G12.450.050.370.250'], ['D23.050.161'], ['D23.050.301'], ['D20.215.894.135'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.485', 'E05.478.550.550'], ['M01.060.703'], ['C01.150.252.223.500.750', 'C01... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Unique CRF01_AE Gag CTL epitopes associated with lower HIV-viral load and delayed disease progression in a cohort of HIV-infected Thais. | Cytotoxic T Lymphocytes (CTLs) play a central role in controlling HIV-replication. Although numerous CTL epitopes have been described, most are in subtype B or C infection. Little is known about CTL responses in CRF01_AE infection. Gag CTL responses were investigated in a cohort of 137 treatment-na?ve HIV-1 infected Th... | ['Adolescent', 'Adult', 'Enzyme-Linked Immunospot Assay', 'Epitopes, T-Lymphocyte', 'Female', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'T-Lymphocytes, Cytotoxic', 'Viral Load', 'Young Adult'] | 21,826,201 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.508', 'E05.200.500.508', 'E05.242.551', 'E05.478.566.350.170.500', 'E05.478.566.380.360.500', 'E05.478.583.400.170.500', 'E05.601.470.350.170.500', 'E05.601.470.380.360.500'], ['D23.050.550.402'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Osteoporosis]. | Calcium supplements should be used according to the dietary intakes. Daily vitamin D supplements have beneficial on bone and extraskeletal effects. Denosumab is registered in Switzerland for the treatment of postmenopausal osteoporosis and to prevent bone loss induced by sex hormone deprivation therapies in men and wom... | ['Bone Density Conservation Agents', 'Calcium, Dietary', 'Humans', 'Osteoporosis', 'Vitamin D'] | 21,400,947 | [['D27.505.696.242'], ['D01.146.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.198.579', 'C18.452.104.579'], ['D04.210.500.812.768']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Substrate Optimization in Baby Hamster Kidney Cell Culture for Foot and Mouth Disease Virus Vaccine Using the Taguchi Method. | Cell culture is one of the most commonly used techniques in the production of biological products. Many physical and chemical parameters may affect cell growth and proliferation. This study was conducted to investigate the effect of chemical components as supplements using the experimental design method, which aimed at... | ['Amino Acids', 'Animals', 'Cell Count', 'Cell Culture Techniques', 'Cells, Cultured', 'Cricetinae', 'Foot-and-Mouth Disease Virus', 'Glucose', 'Hydrogen-Ion Concentration', 'Kidney', 'Polyethylene Glycols', 'Proteins', 'Viral Vaccines', 'Vitamins'] | 32,742,521 | [['D12.125'], ['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251'], ['B01.050.150.900.649.313.992.635.075.250'], ['B04.820.578.750.070.250'], ['D09.947.875.359.448'], ['G02.300'], ['A05.810.453'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Connective tissue repair in zinc deficiency. An ultrastructural morphometric study in perforated mesentery in rats. | OBJECTIVE: To quantify measures of healing in zinc-deficient and healthy rats.DESIGN: Randomized study.MATERIAL: 30 male Sprague-Dawley rats.INTERVENTIONS: Zinc deficiency was induced in half the rats. All rats underwent laparotomy and standard perforations were made in the small intestinal mesentery with a scalpel. At... | ['Animals', 'Cell Membrane', 'Connective Tissue', 'Endoplasmic Reticulum', 'Male', 'Mesentery', 'Microscopy, Electron', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Wound Healing', 'Zinc'] | 1,356,465 | [['B01.050'], ['A11.284.149'], ['A10.165'], ['A11.284.430.214.190.875.248'], ['A01.923.047.025.600.451'], ['E01.370.350.515.402', 'E05.595.402'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.7... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Life-Space Mobility Change Predicts 6-Month Mortality. | OBJECTIVES: To examine 6-month change in life-space mobility as a predictor of subsequent 6-month mortality in community-dwelling older adults.DESIGN: Prospective cohort study.SETTING: Community-dwelling older adults from five Alabama counties in the University of Alabama at Birmingham (UAB) Study of Aging.PARTICIPANTS... | ['Activities of Daily Living', 'Aged', 'Aging', 'Alabama', 'Female', 'Geriatric Assessment', 'Humans', 'Male', 'Mobility Limitation', 'Mortality', 'Prospective Studies', 'Risk Factors'] | 28,152,168 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['G07.345.124'], ['Z01.107.567.875.075.100', 'Z01.107.567.875.750.100'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Lymphomatoid granulomatosis with impaired cellular immunity. Eight year survival without treatment. | Lymphomatoid granulomatosis (LYG), a non-neoplastic lymphoreticular disorder, was diagnosed in a 65-year-old woman. Chest radiographs demonstrated bilateral lower lobe nodular infiltrates. Percutaneous needle biopsy of the lung showed an infiltrate composed of plasma cells, lymphocytes and large histiocytic-like cells.... | ['Aged', 'Female', 'Humans', 'Immunity, Cellular', 'In Vitro Techniques', 'Lung Diseases', 'Lymphomatoid Granulomatosis', 'Mitogens'] | 6,641,317 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.400'], ['E05.481'], ['C08.381'], ['C04.557.386.480.150.600', 'C04.834.567', 'C15.604.515.569.480.150.600', 'C20.683.515.761.480.150.600'], ['D27.505.519.593.624']] | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ionic conductivity of the aqueous layer separating a lipid bilayer membrane and a glass support. | The in-plane ionic conductivity of the approximately 1-nm-thick aqueous layer separating a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) bilayer membrane and a glass support was investigated. The aqueous layer conductivity was measured by tip-dip deposition of a POPC bilayer onto the surface of a 20- to 75-mi... | ['Electric Conductivity', 'Glass', 'Lipid Bilayers', 'Membranes, Artificial', 'Phosphatidylcholines', 'Potassium', 'Surface Properties', 'Water'] | 17,129,059 | [['G01.358.500.249.277'], ['J01.637.437'], ['D10.570.510', 'J01.637.087.500.510'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D10.570.755.375.760.400.800'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['G02.860'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.92... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pathophysiological study of chronic necrotizing pulmonary aspergillosis. | The aim of the present study is to define the characteristics of the clinical and histopathological features of chronic necrotizing pulmonary aspergillosis (CNPA) cases with severe hemoptysis. We conducted a histological study of three patients clinically diagnosed as having CNPA who had hemoptysis for 5 years. A tuber... | ['Aged', 'Antifungal Agents', 'Aspergillus', 'Fatal Outcome', 'Female', 'Hemoptysis', 'Humans', 'Invasive Pulmonary Aspergillosis', 'Lung', 'Lung Diseases, Fungal', 'Male', 'Radiography'] | 19,050,352 | [['M01.060.116.100'], ['D27.505.954.122.136'], ['B01.300.381.081'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C08.381.348', 'C23.550.414.896', 'C23.888.852.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.703.080.768.750', 'C01.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Nocturnal pulse oximetry diagnosis for screening pediatric obstructive sleep apnea syndrome]. | We evaluated the diagnostic value of pulse oximetry during sleep in pediatric obstructive sleep apnea syndrome (OSAS) caused by adenoid-tonsil hypertrophy. Subjects were 22 healthy children free of symptoms such as snoring, sleep apnea and oral breathing and 163 children suspected of OSAS with snoring or sleep apnea. S... | ['Adenoidectomy', 'Child', 'Female', 'Humans', 'Male', 'Oximetry', 'Sleep Apnea, Obstructive', 'Tonsillectomy'] | 14,733,119 | [['E04.580.068'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.386.700.100.600', 'E05.200.124.100.100.600'], ['C08.618.085.852.850', 'C10.886.425.800.750.850'], ['E04.580.848']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The cannabinoid CB1 receptor is expressed in pancreatic delta-cells. | Antagonists of cannabinoid CB1 receptor (CB1, CNR1) promote weight loss and decrease hyperglycemia in patients with type 2 diabetes. While the endocannabinoid system may modulate islet hormone secretion, the cell-type expressing CB1 receptor in islets has not been fully resolved. In this study, we verified receptor gen... | ['Amidohydrolases', 'Animals', 'Cell Line', 'Humans', 'Mice', 'Mice, Inbred Strains', 'Monoacylglycerol Lipases', 'Rats', 'Rats, Inbred Strains', 'Receptor, Cannabinoid, CB1', 'Somatostatin-Secreting Cells'] | 18,505,678 | [['D08.811.277.087'], ['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['D08.811.277.352.100.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.76... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening for carriers of the avian cartilage proteoglycan core protein defect, nanomelia, by denaturing gradient gel electrophoresis. | The avian mutation, nanomelia, is an autosomal recessive embryonic lethal. Homozygous embryos show hypoplasia of the limbs and a parrot-like beak. Biochemical studies have associated this phenotype with the absence of the major cartilage-specific proteoglycan core protein. In a previous study, a DNA polymorphism was id... | ['Aggrecans', 'Animals', 'Birds', 'Crosses, Genetic', 'Electrophoresis', 'Extracellular Matrix Proteins', 'Female', 'Genes, Lethal', 'Genes, Recessive', 'Heterozygote', 'Lectins, C-Type', 'Male', 'Mutation', 'Polymorphism, Genetic', 'Proteoglycans'] | 8,228,166 | [['D09.698.735.200.500', 'D12.776.395.650.750.687.100', 'D12.776.503.280.437.100', 'D12.776.860.300.140'], ['B01.050'], ['B01.050.150.900.248'], ['E05.393.281'], ['E05.196.401', 'E05.301.300'], ['D12.776.860.300'], ['G05.360.340.024.340.350'], ['G05.360.340.024.340.415', 'G05.420.325'], ['G05.380.383'], ['D12.776.503.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Respiratory symptoms and respiratory-related absence from work among health care workers in Sweden. | OBJECTIVE: To investigate respiratory symptoms and respiratory-related absence from work among Swedish health care workers (HCWs).METHODS: From a postal questionnaire study among a general Swedish working population (n = 12,186), we identified 2156 HCW (555 assistant nurses, 377 nurses, 109 physicians, and 1115 others)... | ['Absenteeism', 'Adult', 'Asthma', 'Cross-Sectional Studies', 'Female', 'Health Personnel', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Occupational Diseases', 'Prevalence', 'Surveys and Questionnaires', 'Sweden'] | 23,294,229 | [['F02.784.692.107'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', ... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Blood Cell Classification Based on Hyperspectral Imaging With Modulated Gabor and CNN. | Cell classification, especially that of white blood cells, plays a very important role in the field of diagnosis and control of major diseases. Compared to traditional optical microscopic imaging, hyperspectral imagery, combined with both spatial and spectral information, provides more wealthy information for recognizi... | ['Algorithms', 'Blood Cells', 'Cytological Techniques', 'Humans', 'Image Processing, Computer-Assisted', 'Microscopy', 'Neural Networks, Computer', 'Wavelet Analysis'] | 30,892,256 | [['G17.035', 'L01.224.050'], ['A11.118', 'A15.145.229'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['G17.485', 'L01.224.050.375.605'], ['E05.959', 'G17.915', 'L01.224.800.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues. | Expanded trinucleotide repeat sequences are the cause of several inherited neurodegenerative diseases. Disease pathogenesis is correlated with several features of somatic instability of these sequences, including further large expansions in postmitotic tissues. The presence of somatic expansions in postmitotic tissues ... | ['Adenosine Triphosphatases', 'Animals', 'Cerebellum', 'DNA Mismatch Repair', 'DNA Repair Enzymes', 'DNA-Binding Proteins', 'Friedreich Ataxia', 'Ganglia, Spinal', 'Genomic Instability', 'Humans', 'Mice', 'Mice, Transgenic', 'Mismatch Repair Endonuclease PMS2', 'MutS DNA Mismatch-Binding Protein', 'MutS Homolog 2 Prote... | 23,071,719 | [['D08.811.277.040.025'], ['B01.050'], ['A08.186.211.132.810.428.200'], ['G02.111.222.220', 'G05.219.220'], ['D08.811.074'], ['D12.776.260'], ['C10.228.140.252.700.150', 'C10.228.854.787.200', 'C10.574.500.825.200', 'C16.320.400.780.200', 'C18.452.660.300'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide. | Patients with the systemic autoimmune diseases Sj?grens's syndrome and systemic lupus erythematosus often have autoantibodies against the intracellular protein Ro52. Ro52 is an E3 ligase dependent on the ubiquitin conjugation enzymes UBE2D1 and UBE2E1. While Ro52 and UBE2D1 are cytoplasmic proteins, UBE2E1 is localized... | ['Amino Acid Sequence', 'Autoantigens', 'Cell Nucleus', 'Cells, Cultured', 'Cytoplasm', 'Green Fluorescent Proteins', 'HeLa Cells', 'Humans', 'Molecular Sequence Data', 'Nitric Oxide', 'Protein Transport', 'Recombinant Proteins', 'Ribonucleoproteins', 'Transfection', 'Ubiquitin-Conjugating Enzymes', 'Ubiquitin-Protein ... | 18,845,142 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.422'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['A11.284.430.214'], ['D12.776.532.265'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D01.339.387', 'D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis. | To elucidate the possible role of NF-kappaB in mouse skin carcinogenesis we studied the expression of p50 (NF-kappaB1), p52 (NF-kappaB2), p65 (RelA) and IkappaB-alpha inhibitor as well as kappaB-binding activity in adult SENCAR mouse skin, skin papillomas, and squamous cell carcinomas (SCC) generated by a two-stage car... | ['9,10-Dimethyl-1,2-benzanthracene', 'Animals', 'B-Cell Lymphoma 3 Protein', 'Carcinogens', 'Epidermis', 'Female', 'Gene Expression Regulation, Neoplastic', 'I-kappa B Proteins', 'Mice', 'Mice, Inbred SENCAR', 'NF-kappa B', 'NF-kappa B p50 Subunit', 'Proto-Oncogene Proteins', 'Skin Neoplasms', 'Tetradecanoylphorbol Ace... | 10,602,501 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['B01.050'], ['D12.776.624.664.700.165', 'D12.776.930.714'], ['D27.888.569.100'], ['A10.272.497', 'A17.815.250'], ['G05.308.370'], ['D12.644.360.365', 'D12.776.260.420', 'D12.776.476.381', 'D12.776.930.326'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selecting appropriate recall intervals for patients in general dental practice--an audit project to categorize patients according to risk. | UNLABELLED: In 2004, the National Institute for Health and Clinical Excellence (NICE) was asked to prepare guidance for the NHS in England and Wales on the clinical need and cost-effectiveness of a dental recall examination for all patients at an interval based upon their risk from oral disease. (Dental Recall: recall ... | ['Appointments and Schedules', 'Cost-Benefit Analysis', 'Dental Audit', 'Dental Caries Susceptibility', 'Disease Susceptibility', 'England', 'General Practice, Dental', 'Guideline Adherence', 'Humans', 'Mouth Neoplasms', 'Needs Assessment', 'Periodontal Diseases', 'Practice Guidelines as Topic', 'Risk Assessment', 'Sta... | 18,507,227 | [['N04.452.095'], ['N03.219.151.125'], ['N04.761.700.250.295', 'N05.700.175.250'], ['G10.549.140'], ['C23.550.291.687', 'G07.100.250'], ['Z01.542.363.300'], ['H02.163.342'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.591', 'C07.465.530'], ['I02.594', 'N03.349.380.... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for application of ascorbyl palmitate. | The aim of this study was to improve the chemical stability of ascorbyl palmitate (AP) in a colloidal lipid carrier for its topical use. For this purpose, AP-loaded solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) and for comparison, a nanoemulsion (NE) were prepared employing the high pressure homo... | ['Ascorbic Acid', 'Calibration', 'Calorimetry, Differential Scanning', 'Chemical Phenomena', 'Chemistry, Pharmaceutical', 'Chemistry, Physical', 'Crystallization', 'Crystallography, X-Ray', 'Drug Carriers', 'Drug Stability', 'Drug Storage', 'Electrochemistry', 'Excipients', 'Hydrogels', 'Liposomes', 'Microspheres', 'Pa... | 16,124,399 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['E05.978.155'], ['E05.196.131.310', 'E05.196.370.310'], ['G02'], ['H01.158.703.007', 'H01.181.466'], ['H01.181.529'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.330'], ['E05.916.350'], ['H01.181.529.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Serum elevations of soluble Fas (CD95/apo-I) concur in deregulating T cell apoptosis during active lupus disease. | Apoptosis is deregulated in active systemic lupus erythematosus and Fas is overexpressed by T cells, although the role of its soluble form (sFas) is unclear. We have explored both the biological significance and structure of sFas in relation to the disease activity. Serum levels of both sFas and sFas-L were correlated ... | ['Apoptosis', 'CD3 Complex', 'Caspases', 'Cells, Cultured', 'Enzyme Activation', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Flow Cytometry', 'Humans', 'In Situ Nick-End Labeling', 'Lupus Erythematosus, Systemic', 'Mitochondria', 'Poly(ADP-ribose) Polymerases', 'Protein Isoforms', 'T-Lymphocytes', 'fas Receptor'] | 12,049,185 | [['G04.146.954.035'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.251'], ['G02.111.263', 'G03.328'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Making sausage--effective management of enterprise-wide clinical IT projects. | Unlike most other industries in which company employees are, well, company employees, U.S. hospitals are typically run by both employees (nurses, technicians, and administrative staff) and independent entrepreneurs (physicians and nurse practitioners). Therefore, major enterprise-wide clinical IT projects can never sim... | ['Diffusion of Innovation', 'Efficiency, Organizational', 'Hospital Information Systems', 'Organizational Objectives', 'United States'] | 15,869,213 | [['L01.143.320'], ['N04.452.209.500'], ['N04.452.442.452.452', 'N04.452.515.360'], ['N04.452.615'], ['Z01.107.567.875']] | ['Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
CHIN (community healthcare information network) provides vital healthcare linkages. | When the term "electronic data interchange" (EDI) was first introduced, it referred to purchase orders, electronic claims, and electronic remittance processing. Those EDI applications are becoming commonplace now, however, and new applications for EDI technology are being developed. Healthcare financial managers should... | ['Centers for Medicare and Medicaid Services, U.S.', 'Comprehensive Health Care', 'Computer Communication Networks', 'Financial Management, Hospital', 'Insurance Claim Reporting', 'Medical Record Linkage', 'Medical Records Systems, Computerized', 'Referral and Consultation', 'United States'] | 10,145,934 | [['I01.409.418.750.600.310', 'N03.540.348.500.500.600.550'], ['N04.590.233'], ['L01.224.230.110'], ['N02.278.216.500.875', 'N03.219.463.280', 'N04.452.442.452.180'], ['N03.219.521.576.210'], ['E05.318.308.940.968.500', 'N04.452.859.564.550', 'N05.715.360.300.715.500.500', 'N06.850.520.308.940.968.500'], ['E05.318.308.9... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
An accumulation of tandem DNA repeats on the Y chromosome in Silene latifolia during early stages of sex chromosome evolution. | Sex chromosomes in mammals are about 300 million years old and typically have a highly degenerated Y chromosome. The sex chromosomes in the dioecious plant Silene latifolia in contrast, represent an early stage of evolution in which functional X-Y gene pairs are still frequent. In this study, we characterize a novel ta... | ['Base Sequence', 'DNA Primers', 'DNA, Plant', 'Evolution, Molecular', 'In Situ Hybridization, Fluorescence', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Sequence Homology, Nucleic Acid', 'Sex Chromosomes', 'Silene', 'Species Specificity', 'Tandem Repeat Sequences', 'Y Chromosome'] | 16,612,641 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.435'], ['G05.045.250', 'G16.075.250'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Amyloids and yeast prion biology. | The prions (infectious proteins) of Saccharomyces cerevisiae are proteins acting as genes, by templating their conformation from one molecule to another in analogy to DNA templating its sequence. Most yeast prions are amyloid forms of normally soluble proteins, and a single protein sequence can have any of several self... | ['Amino Acid Sequence', 'Amyloid', 'Fungal Proteins', 'Fungi', 'Genes, Fungal', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Prions', 'Protein Conformation'] | 23,379,365 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D05.500.049', 'D12.776.049'], ['D12.776.354'], ['B01.300'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['L01.453.245.667'], ['D12.776.785'], ['G02.111.570.820.709'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Collagen-collagen versus collagen-proteoglycan interactions in the determination of cartilage strength. | For articular cartilage to function as a stress-reducing layer in the joint, it must both deform to an appropriate level to achieve load-spreading as well as remain structurally coherent. Combined micromechanical and enzymatic studies of cartilage have demonstrated that the bulk of the extractable proteoglycans, while ... | ['Animals', 'Biomechanical Phenomena', 'Cartilage, Articular', 'Cattle', 'Collagen', 'Electrophoresis', 'Proteoglycans', 'Tensile Strength'] | 2,222,534 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E05.196.401', 'E05.301.300'], ['D09.698.735', 'D12.776.395.650'], ['G01.374.850']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The pattern of fatal fibrinous pneumonia (shipping fever) affecting calves in a large feedlot in Alberta (1985-1988). | Data from a retrospective field study were used to describe the epidemiology of fatal fibrinous pneumonia as it affected beef calves entering a large commercial feedlot in southwestern Alberta during the fall months of y 1985 to 1988. A chute-side computer system was used to record processing and health data on 58885 c... | ['Alberta', 'Animal Husbandry', 'Animals', 'Cattle', 'Disease Outbreaks', 'Incidence', 'Pasteurellosis, Pneumonic', 'Retrospective Studies'] | 8,748,443 | [['Z01.107.567.176.064'], ['J01.040.090'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['N06.850.290'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C01.150.252.400.700.675', 'C01.748.085.600', 'C01.925.782.580.600.600.648', 'C08.730.085.6... | ['Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Elevated BIS and Entropy values after sugammadex or neostigmine: an electroencephalographic or electromyographic phenomenon? | BACKGROUND: Sugammadex is designed to antagonize neuromuscular blockade (NMB) induced by rocuronium or vecuronium. In clinical practice, we have noticed a rise in the numerical values of bispectral index (BIS) and Entropy, two electroencephalogram (EEG) - based depth of anesthesia monitors, during the reversal of the N... | ['Adult', 'Blood-Brain Barrier', 'Double-Blind Method', 'Electroencephalography', 'Electromyography', 'Entropy', 'Humans', 'Middle Aged', 'Neostigmine', 'Neuromuscular Blockade', 'Prospective Studies', 'Sugammadex', 'gamma-Cyclodextrins'] | 22,289,106 | [['M01.060.116'], ['A07.035', 'A08.186.211.035'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.405.255', 'E01.370.530.255'], ['G01.906.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.092.877.674... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[2 cases of fibroepithelial polyp of the ureter]. | Fibroepithelial polyps of the ureter, a mesodermal benign tumor, are rare. The first case of a fibroepithelial ureteral polyp associated with bilateral complete ureteral duplication and another case associated with bilateral hydronephrosis are reported. The first case suggested a malformative congenital etiology. The t... | ['Adult', 'Humans', 'Hydronephrosis', 'Kidney Neoplasms', 'Kidney Pelvis', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Polyps', 'Ureter', 'Ureteral Neoplasms'] | 2,392,737 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.307', 'C13.351.968.419.307'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['A05.810.453.537'], ['M01.060.116.630'], ['C04.651'], ['C23.300.825'], ['A05.810.776'], ['C04.588.9... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of nonresective operations for complicated peptic ulcer disease in a high-risk population. | Over the past two decades, surgery for complicated peptic ulcer disease has evolved to a "less-is-more" approach due predominately to improved medical therapy. This study sought to determine whether a nonresective operative strategy has been an effective and prudent approach. A 20-year retrospective evaluation was cond... | ['Adult', 'Aged', 'Digestive System Surgical Procedures', 'Emergency Medical Services', 'Female', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Peptic Ulcer Hemorrhage', 'Peptic Ulcer Perforation', 'Retrospective Studies', 'United States', 'Veterans'] | 21,105,630 | [['M01.060.116'], ['M01.060.116.100'], ['E04.210'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['C06.405.227.700', 'C23.550.414.788.700'], ['C06.405.469.275.800.698', 'C06.405.748.586.698'], ['E05.318.372.500.500.500', 'E05.318.372.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Second primary myogenic sarcoma in a patient with bilateral retinoblastoma. | Retinoblastoma is the primary ocular malignancy affecting children under 6 years of age. The development of second malignant tumors in survivors of hereditary retinoblastoma is a well-known clinical entity and a major cause of morbidity and mortality. Rhabdomyosarcomas as second primary tumors have been only rarely des... | ['Eye Neoplasms', 'Female', 'Humans', 'Infant', 'Neoplasms, Second Primary', 'Retinoblastoma', 'Rhabdomyosarcoma'] | 15,552,818 | [['C04.588.364', 'C11.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.692'], ['C04.557.465.625.600.725', 'C04.557.470.670.725', 'C04.557.580.625.600.725', 'C04.588.364.818.760', 'C11.270.862', 'C11.319.475.760', 'C11.768.717.760'], ['C04.557.450.590.550.660', 'C04.557.450.795.550.660']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Skin cancer recognition by computer vision. | Automatic detection of several features characteristic of basal cell epitheliomas is described. The features selected for this feasibility study are semitranslucency, telangiectasia, ulcer, crust, and tumor border. Image processing methods used in this study include frequency analysis of the Fourier transform of the im... | ['Carcinoma, Basal Cell', 'Diagnosis, Differential', 'Expert Systems', 'Feasibility Studies', 'Fourier Analysis', 'Humans', 'Image Interpretation, Computer-Assisted', 'Minicomputers', 'Pattern Recognition, Automated', 'Photography', 'Skin Neoplasms', 'Skin Ulcer', 'Telangiectasis'] | 2,924,283 | [['C04.557.470.200.165', 'C04.557.470.565.165'], ['E01.171'], ['L01.224.050.375.190'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The fluorescein isothiocyanate-binding site of the plasma-membrane H+-ATPase of Neurospora crassa. | The mammalian (Na+,K+), Ca2+-, and (H+,K+)-ATPases contain a well-characterized lysine residue that reacts with fluorescein 5'-isothiocyanate (FITC); enzymatic activity is protected by ATP, suggesting that the residue is located in or near the nucleotide-binding domain. In this study, the plasma-membrane H+-ATPase of N... | ['Amino Acid Sequence', 'Binding Sites', 'Fluorescein-5-isothiocyanate', 'Fluoresceins', 'Hydrogen-Ion Concentration', 'Kinetics', 'Magnesium', 'Molecular Sequence Data', 'Neurospora', 'Neurospora crassa', 'Proton-Translocating ATPases', 'Thiocyanates'] | 2,904,434 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['D02.455.426.779.347.400', 'D02.500.375.250', 'D02.886.250.250', 'D03.633.300.953.275.400', 'D04.711.347.400'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Activin A is increased in the nucleus accumbens following a cocaine binge. | Drug addiction is a long-lasting disease characterized by compulsive drug intake mediated in part by neuronal and biological adaptations in key brain areas, such as the nucleus accumbens (NAc). While we previously demonstrated involvement of the activin 2a receptor in drug taking, the role of its ligand, activin A, in ... | ['Activins', 'Animals', 'Astrocytes', 'Biomarkers', 'Cocaine-Related Disorders', 'Enzyme-Linked Immunosorbent Assay', 'Fluorescent Antibody Technique', 'Male', 'Microglia', 'Neurons', 'Nucleus Accumbens', 'Rats'] | 28,272,550 | [['D06.472.334.500', 'D06.472.699.009', 'D12.644.548.009', 'D12.776.395.022'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['D23.101'], ['C25.775.300', 'F03.900.300'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.607.512.240', 'E... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sex ratio of spontaneously aborted fetuses and delivered neonates in second trimester. | The author investigated in patient material from 12 years 251 cases involving spontaneous abortion and delivery in the second trimester. The material included 28 sets of twins and one set of triplets, thus the total number of fetuses and neonates was 281. The sex ratio was 136.1, higher than that documented natural sex... | ['Abortion, Spontaneous', 'Female', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Pregnancy', 'Pregnancy Trimester, Second', 'Sex Ratio', 'Triplets', 'Twins'] | 1,879,596 | [['C13.703.039', 'G08.686.784.769.496.125'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['G08.686.784.769'], ['G08.686.707.490'], ['G05.815', 'I01.240.800.815', 'N01.224.803.815', 'N06.850.505.400.850.815'], ['M01.438.768'],... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Retinol-binding protein 4 and insulin resistance are related to body fat in primary and secondary schoolchildren: the Ouro Preto study. | PURPOSE: Evidence suggests that plasma retinol-binding protein 4 (RBP4) and insulin resistance are related to body fat (BF). We aimed to assess the relationship between RBP4 and insulin resistance with obesity in a mixed (skin color) cohort of the Brazilian population.METHODS: A nested case-control study was conducted ... | ['Adolescent', 'Blood Pressure', 'Body Composition', 'Brazil', 'Cardiovascular Diseases', 'Case-Control Studies', 'Child', 'Fasting', 'Female', 'Humans', 'Insulin', 'Insulin Resistance', 'Lipids', 'Male', 'Obesity', 'Retinol-Binding Proteins, Plasma', 'Risk Factors', 'Skin Pigmentation'] | 23,764,679 | [['M01.060.057'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['Z01.107.757.176'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of the glucagon-like peptide-1 (GLP-1) analogues exenatide, exenatide extended-release, and of the dipeptidylpeptidase-4 (DPP-4) inhibitor sitagliptin on glucose metabolism in healthy cats. | Incretin analogues and inhibitors of the breakdown of endogenous incretins are antidiabetic drugs that increase â-cell proliferation and glucose-stimulated insulin secretion in rodents and humans. Objectives were to test whether exenatide, exenatide extended-release, and sitagliptin can be safely used in cats, to ident... | ['Animals', 'Area Under Curve', 'Cats', 'Exenatide', 'Glucagon-Like Peptide 1', 'Glucose', 'Humans', 'Incretins', 'Insulin', 'Insulin Secretion', 'Peptides', 'Sitagliptin Phosphate', 'Venoms'] | 25,648,286 | [['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D12.644.187', 'D20.888.300', 'D23.946.833.300'], ['D06.472.317.680.500.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.399.472.580... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Multi-institutional analysis of sequential intravesical gemcitabine and mitomycin C chemotherapy for non-muscle invasive bladder cancer. | OBJECTIVE: Apart from cystectomy, few treatment options exist for the management of bacillus Calmette-Guerin refractory non-muscle invasive bladder cancer (NMIBC). We report a multi-institutional experience with sequential intravesical combination chemotherapy using gemcitabine and mitomycin C (MMC) for NMIBC in the tr... | ['Academic Medical Centers', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Cystectomy', 'Deoxycytidine', 'Disease-Free Survival', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mitomycin', 'Recurrence', 'Retrospective Studies', 'Treatment Outcome',... | 23,510,863 | [['N02.278.020'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E04.950.774.150'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.5... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Increase by ANP and ADH of the duration of activation and deactivation of the cardiopulmonary baroreceptor reflex: modification in the presence of left ventricular hypertrophy]. | The involvement of cardiopulmonary and arterial sinoaortic receptors in the control of antidiuretic hormone (ADH) and atrial natriuretic peptide (ANP) release is still controversial in humans. Moreover, it is not clear if this control may be impaired in hypertensive patients with left ventricular hypertrophy (LVH). We ... | ['Adolescent', 'Adult', 'Atrial Natriuretic Factor', 'Blood Pressure', 'Cardiomegaly', 'Electrocardiography', 'Heart', 'Heart Ventricles', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Pressoreceptors', 'Pressure', 'Reflex', 'Vasopressins'] | 2,148,502 | [['M01.060.057'], ['M01.060.116'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.195', 'C23.300.775.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Loss of isoantigens A, B and H in prostate. | Formalin-fixed tissues from 65 prostates were grouped and investigated by the technic of mixed cell agglutination reaction (MCAR) for studying isoantigens A, B and H. The results of this study indicated that the MCAR was strongly positive at the epithelium of the acini in the majority of patients with benign prostatic ... | ['Adenocarcinoma', 'Adolescent', 'Adult', 'Age Factors', 'Agglutination Tests', 'Blood Group Antigens', 'Child', 'Child, Preschool', 'Epithelium', 'Humans', 'Infant', 'Infant, Newborn', 'Isoantigens', 'Male', 'Methods', 'Neoplasm Metastasis', 'Prostate', 'Prostatic Hyperplasia', 'Prostatic Neoplasms'] | 4,120,302 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['D23.050.301.290', 'D23.050.705.230'], ['M01.060.406'], ['M01.060.406.448'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impaired intestinal wound healing in Fhl2-deficient mice is due to disturbed collagen metabolism. | Four and one half LIM domain protein FHL2 participates in many cellular processes involved in tissue repair such as regulation of gene expression, cytoarchitecture, cell adhesion, migration and signal transduction. The repair process after wounding is initiated by the release of peptides and bioactive lipids. These mol... | ['Animals', 'Collagen', 'Collagen Type III', 'Homeodomain Proteins', 'Intestinal Diseases', 'Intestinal Mucosa', 'Intestines', 'LIM-Homeodomain Proteins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Muscle Proteins', 'Shear Strength', 'Stress, Mechanical', 'Transcription Factors', 'Wound Healing'] | 18,950,620 | [['B01.050'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D05.750.078.280.300.300', 'D12.776.860.300.250.300.300'], ['D12.776.260.400'], ['C06.405.469'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['D12.776.260.529', 'D12.776.512.249'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Topical ivermectin: a new successful treatment for scabies. | Ivermectin is the only one of the avermectins that has been widely used in humans, since it is recommended as the treatment of choice for onchocerciasis, a filariasis that produces "river blindness," a parasitic endemic infestation in countries of West Equatorial Africa and in some areas of Central and South America. A... | ['Administration, Cutaneous', 'Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Insecticides', 'Ivermectin', 'Male', 'Scabies', 'Treatment Outcome'] | 11,207,977 | [['E02.319.267.120.060'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D02.540.576.500.997'], ['C01.610.858.211.480.708', 'C17.800.838.775.800'], ['E01.789.800', 'N04.761.559.590.80... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ethanol induced changes in cyclin-dependent kinase-5 activity and its activators, P35, P67 (Munc-18) in rat brain. | The expression of cyclin-dependent kinase-5 (Cdk5) and its regulators, p35 and p67 was investigated in adult rat cerebral cortex and cerebellum, using an experimental paradigm of in vivo chronic ethanol exposure. In parallel, the activity of Cdk5 kinase was measured using a specific substrate histone-H1 peptide. Wester... | ['Animals', 'Brain Chemistry', 'Central Nervous System Depressants', 'Cerebellum', 'Cerebral Cortex', 'Cyclin-Dependent Kinase 5', 'Cyclin-Dependent Kinases', 'Enzyme Activation', 'Ethanol', 'Male', 'Munc18 Proteins', 'Nerve Tissue Proteins', 'Rats', 'Rats, Wistar', 'Vesicular Transport Proteins'] | 11,479,016 | [['B01.050'], ['G02.111.150', 'G03.185'], ['D27.505.696.277', 'D27.505.954.427.210'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['D08.811.913.696.620.682.700.646.500.500.500', 'D12.644.360.250.067.875', 'D12.776.167.200.067.875', 'D12.776.476.250.067.875'], ['D08.811.913.696.620.682.700.646.500'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diselenide-Labeled Cyclic Polystyrene with Multiple Responses: Facile Synthesis, Tunable Size, and Topology. | Diselenide-containing polymers have attracted more and more attention due to their redox sensitivity and bioapplication. In this work, a bifunctional diselenocarbonate is prepared and used to mediate the reversible addition-fragmentation chain transfer (RAFT) polymerization, producing á,ù-selenocarbonate-labeled telech... | ['Molecular Structure', 'Organoselenium Compounds', 'Polystyrenes', 'Selenium'] | 27,071,752 | [['G02.111.570', 'G02.466'], ['D02.731'], ['D02.455.426.559.389.150.750.800.830', 'D05.750.716.579', 'D25.720.716.579', 'J01.637.051.720.716.579'], ['D01.268.185.850', 'D01.578.700']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Crystallization and preliminary X-ray crystallographic analysis of human quinolinate phosphoribosyltransferase. | Quinolinate phosphoribosyltransferase (QPRTase) is a key NAD-biosynthetic enzyme which catalyzes the transfer of quinolinic acid to 5-phosphoribosyl-1-pyrophosphate, yielding nicotinic acid mononucleotide. Homo sapiens QPRTase (Hs-QPRTase) appeared as a hexamer during purification and the protein was crystallized. Diff... | ['Animals', 'Crystallization', 'Crystallography, X-Ray', 'Humans', 'Molecular Sequence Data', 'NAD', 'Pentosyltransferases', 'Protein Structure, Quaternary'] | 21,206,019 | [['B01.050'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['D08.811.913.400.725'], ['G02.111.570.820.709.550']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Galactose-1-phosphate uridylyltransferase: identification of histidine-164 and histidine-166 as critical residues by site-directed mutagenesis. | Galactose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-glucose and galactose-1-P with UDP-galactose and glucose-1-P by a double-displacement mechanism involving the compulsory formation of a uridylyl enzyme intermediate. The uridylyl group is covalently bonded to the N3 position of a histidine r... | ['Asparagine', 'Binding Sites', 'Catalysis', 'Cloning, Molecular', 'Escherichia coli', 'Genes, Regulator', 'Histidine', 'Mutation', 'Nucleotidyltransferases', 'Plasmids', 'Protein Conformation', 'Transformation, Bacterial', 'UTP-Hexose-1-Phosphate Uridylyltransferase'] | 2,541,773 | [['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['G02.111.570.120'], ['G02.130'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.425'], ['D12.125.072.329', 'D12.125.142.308'], ['G05.365.590'], ['D08.811.913.696.445'], ['G05.360.600'], ['G02.111.570.820.709'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence of Somatic Dysfunction in Healthy Newborns. | CONTEXT: Recent evidence suggests that osteopathic manipulative treatment of somatic dysfunction in newborns may decrease complications and hospital length of stay. Such dysfunction may result from external forces related to the birth process, but its incidence is unknown.OBJECTIVE: To identify the incidence and patter... | ['Female', 'Humans', 'Incidence', 'Infant, Newborn', 'Male', 'Missouri', 'Musculoskeletal Diseases', 'Osteopathic Medicine', 'Reference Values', 'Retrospective Studies'] | 26,501,758 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703.520'], ['Z01.107.567.875.510.515'], ['C05'], ['H02.403.640'], ['E05.978.810'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
pmg-1, a novel gene specifically expressed during the invasive growth phase of the mammary gland at puberty. | The acquisition of invasive properties is a crucial event during carcinogenesis, determining the clinical outcome. The mammary gland at puberty provides an ideal model for investigating the induction and control of invasive growth. During this growth phase, the mammary epithelium participates in a normal, hormonally co... | ['Age Factors', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Blotting, Southern', 'Epithelium', 'Female', 'Humans', 'In Situ Hybridization', 'Intermediate Filament Proteins', 'Keratins, Hair-Specific', 'Mammary Glands, Animal', 'Mice', 'Mice, Inbred Strains', 'Molecular Sequence Data', 'Pro... | 9,287,118 | [['N05.715.350.075', 'N06.850.490.250'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.40... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Phenotype of mononuclear leucocytes resident in rat major salivary and lacrimal glands. | The phenotypic distribution of lymphocytes and mononuclear phagocytes resident in rat secretory glands was examined. Isolated exocrine gland mononuclear leucocyte populations contained 50-61% W3/13+ T cells and greater proportions of W3/25+ T helper cells relative to OX8+ T suppressor cells. Surface Ig+ cells (sIg) con... | ['Animals', 'Antigens, Surface', 'Cell Adhesion', 'Centrifugation, Density Gradient', 'Lacrimal Apparatus', 'Leukocytes, Mononuclear', 'Phagocytosis', 'Rats', 'Rats, Inbred F344', 'Receptors, Antigen, B-Cell', 'Salivary Glands'] | 3,391,644 | [['B01.050'], ['D23.050.301'], ['G04.022'], ['E05.181.724.336', 'E05.196.941.336'], ['A09.371.463', 'A10.336.422'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.200', 'B... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Blood flow in the left anterior descending coronary artery in children with ventricular septal defect. | High-frequency echocardiography offers a noninvasive approach for imaging left anterior descending coronary artery (LAD) blood flow from a transthoracic window. The purpose of this study was to assess the effects of left ventricular (LV) volume overload on LAD flow in pediatric patients with ventricular septal defect (... | ['Blood Flow Velocity', 'Coronary Circulation', 'Coronary Vessels', 'Echocardiography', 'Echocardiography, Doppler', 'Heart Septal Defects, Ventricular', 'Humans', 'Infant', 'Observer Variation', 'Ventricular Function, Left'] | 12,174,350 | [['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.324'], ['A07.015.114.269', 'A07.015.908.194'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['C14.240.400.560.540', 'C14.280.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cell-free propagation of prion strains. | Prions are the infectious agents responsible for prion diseases, which appear to be composed exclusively by the misfolded prion protein (PrP(Sc)). Disease is transmitted by the autocatalytic propagation of PrP(Sc) misfolding at the expense of the normal prion protein. The biggest challenge of the prion hypothesis has b... | ['Animals', 'Brain', 'Cell-Free System', 'Female', 'Humans', 'Mice', 'Mice, Inbred C57BL', 'PrPSc Proteins', 'Prion Diseases', 'Protein Isoforms', 'Tissue Extracts'] | 18,800,058 | [['B01.050'], ['A08.186.211'], ['A11.284.835.168'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.776.785.340.750'], ['C01.207.800', 'C10.228.228.800', 'C10.574.843'], ['D12.776.800'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transition, It's More Than Just An Event: Supporting Young People With Type 1 Diabetes. | This paper discusses the importance of holistic person-centered care coordination services for young people with type 1 diabetes as they transition to adult health services. In response to the growing need for comprehensive, flexible, person-centered care for young people with chronic conditions, the new service Trapez... | ['Adaptation, Psychological', 'Adolescent', 'Australia', 'Diabetes Mellitus, Type 1', 'Humans', 'Long-Term Care', 'Nurse-Patient Relations', 'Patient Care Team', 'Patient-Centered Care', 'Quality of Life', 'Sampling Studies', 'Sickness Impact Profile', 'Transition to Adult Care', 'Young Adult'] | 26,044,910 | [['F01.058'], ['M01.060.057'], ['Z01.639.100', 'Z01.678.100.373'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.476', 'N02.421.585.476'], ['F01.829.401.650.600', 'N05.300.660.560'], ['N04.590.715'], ['N04.590.233.727.407'], ['I01.800', 'K01.752.400.75... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Influence of vitreomacular adhesion on the development of exudative age-related macular degeneration: 4-year results of a longitudinal study. | PURPOSE: To investigate the influence of vitreomacular adhesion (VMA) on development of choroidal neovascularization (CNV) in eyes with age-related macular degeneration.METHODS: In a prospective study, patients with Age-Related Eye Disease Study Category IV age-related macular degeneration underwent standardized examin... | ['Aged', 'Aged, 80 and over', 'Choroidal Neovascularization', 'Exudates and Transudates', 'Eye Diseases', 'Female', 'Humans', 'Longitudinal Studies', 'Macula Lutea', 'Macular Degeneration', 'Male', 'Middle Aged', 'Prospective Studies', 'Tissue Adhesions', 'Tomography, Optical Coherence', 'Vitreous Body'] | 22,105,497 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.941.160.244', 'C23.550.589.500.145'], ['A12.383'], ['C11'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['A09.371.729.522'], ['C11.768.585.439'], ['M01.060.116.630'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ultrasound analysis of diaphragm kinetics and the diagnosis of airway obstruction: the role of the M-mode index of obstruction. | Diaphragm motion in forced expiration can be analyzed using M-mode ultrasound in an anterior subcostal approach. Maximum expiratory diaphragmatic excursion (EDEMax) and forced expiratory diaphragmatic excursion in the first second (FEDE1) are considered the physiopathological analogues of vital capacity (VC) and forced... | ['Aged', 'Airway Obstruction', 'Diaphragm', 'Female', 'Forced Expiratory Volume', 'Humans', 'Image Interpretation, Computer-Assisted', 'Kinetics', 'Male', 'Middle Aged', 'Pulmonary Disease, Chronic Obstructive', 'Spirometry', 'Ultrasonography', 'Vital Capacity'] | 24,486,237 | [['M01.060.116.100'], ['C08.618.846.185'], ['A02.633.567.900.300'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['G01.374.661', 'G02.111.490'], ['M01.060.116.630'], ['C08.381.495.389'], ['E01.370.386.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Electric vehicle recycling 2020: Key component power electronics. | Electromobility will play a key role in order to reach the specified ambitious greenhouse gas reduction targets in the German transport sector of 42% between 1990 and 2030. Subsequently, a significant rise in the sale of electric vehicles (EVs) is to be anticipated in future. The amount of EVs to be recycled will rise ... | ['Electronics', 'Metals', 'Recycling'] | 29,502,494 | [['H01.671.293'], ['D01.552'], ['N06.850.780.200.800.800.525', 'N06.850.860.510.244']] | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Knowledge, attitudes and practice of condom use among males aged (15-49) years in Erbil Governorate. | BACKGROUND AND OBJECTIVES: Globally, condom is an important method of family planning and prevention of sexually transmitted infections especially human immune deficiency virus HIV/ acquired immune deficiency syndrome AIDS. Family planning saves lives of women and children and improves the quality of life. This study w... | ['Adolescent', 'Adult', 'Condoms', 'Cross-Sectional Studies', 'Family Characteristics', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Iraq', 'Male', 'Marital Status', 'Middle Aged', 'Safe Sex', 'Social Class', 'Young Adult'] | 22,980,338 | [['M01.060.057'], ['M01.060.116'], ['E07.190.270.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Comparisons of rotavirus VP7-typing monoclonal antibodies by competition binding assay. | Three sets of neutralizing monoclonal antibodies (MAbs) used to type the outer capsid protein VP7 of four group A rotavirus serotypes (1 through 4) were compared in competition immunoassays. Reciprocal competition was observed for each of the VP7 type 2-, 3-, and 4-specific MAbs. The VP7 type 1 MAbs exhibited variable ... | ['Antibodies, Monoclonal', 'Antigenic Variation', 'Antigens, Viral', 'Bacterial Typing Techniques', 'Binding, Competitive', 'Capsid', 'Capsid Proteins', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Evaluation Studies as Topic', 'Humans', 'Neutralization Tests', 'Rotavirus'] | 1,372,622 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G05.365.073', 'G12.500.249'], ['D23.050.327'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A21.249.500.250'], ['D12.776.964.970.600.550'], ['E05.478.566.350.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The invasive Asian tiger mosquito Aedes albopictus (Diptera: Culicidae) in Germany: Local reproduction and overwintering. | Within the framework of a German mosquito monitoring programme, the 'Mueckenatlas' (mosquito atlas) has been established as an instrument of citizen participation in mosquito mapping. In 2015, a strikingly large number of Aedes albopictus, which had not been considered established in Germany, was submitted. Three of si... | ['Aedes', 'Animals', 'Environmental Monitoring', 'Epidemiological Monitoring', 'Germany', 'Introduced Species', 'Seasons'] | 27,876,647 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.318.375', 'N06.850.520.460'], ['Z01.542.315'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Low density lipoprotein and liposome mediated uptake and cytotoxic effect of N4-octadecyl-1-beta-D-arabinofuranosylcytosine in Daudi lymphoma cells. | Low density lipoprotein (LDL) receptor-mediated uptake and cytotoxic effects of N4-octadecyl-1-beta-D-arabinofuranosylcytosine (NOAC) were studied in Daudi lymphoma cells. NOAC was either incorporated into LDL or liposomes to compare specific and unspecific uptake mechanisms. Binding of LDL to Daudi cells was not alter... | ['Antineoplastic Agents', 'Burkitt Lymphoma', 'Cell Survival', 'Cytarabine', 'Drug Carriers', 'Endocytosis', 'Hot Temperature', 'Humans', 'Lipoproteins, LDL', 'Liposomes', 'Protein Binding', 'Receptors, LDL', 'Tumor Cells, Cultured'] | 10,408,395 | [['D27.505.954.248'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['G04.346'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['D26.255.260', 'E02.319.300.380'], ['G04.417'], ['G01.906.595.543', 'G16... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Noninvasive real-time visualization of multiple cerebral hemodynamic parameters in whole mouse brains using five-dimensional optoacoustic tomography. | Current functional neuroimaging methods are not adequate for high-resolution whole-brain visualization of neural activity in real time. Here, we show imaging of fast hemodynamic changes in deep mouse brain using fully noninvasive acquisition of five-dimensional optoacoustic data from animals subjected to oxygenation st... | ['Animals', 'Brain', 'Female', 'Functional Neuroimaging', 'Hemodynamics', 'Image Processing, Computer-Assisted', 'Mice', 'Mice, Nude', 'Oxygen', 'Photoacoustic Techniques', 'Tomography'] | 25,586,142 | [['B01.050'], ['A08.186.211'], ['E01.370.350.578.875', 'E01.370.376.537.625', 'E05.629.875'], ['G09.330.380'], ['L01.224.308'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['D01.268.185.550', 'D01.362.670'], ['E01.370.565', 'E05.696'], ['E01.370.350.825']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prostaglandin E2 suppresses lipopolysaccharide-stimulated IFN-beta production. | Macrophages activate the production of cytokines and chemokines in response to LPS through signaling cascades downstream from TLR4. Lipid mediators such as PGE(2), which are produced during inflammatory responses, have been shown to suppress MyD88-dependent gene expression upon TLR4 activation in macrophages. The study... | ['Animals', 'Cell Line', 'Dinoprostone', 'Dose-Response Relationship, Immunologic', 'Endotoxemia', 'Gene Expression Regulation', 'Interferon-beta', 'Lipopolysaccharides', 'Macrophage Activation', 'Macrophages', 'Male', 'Mice', 'Myeloid Differentiation Factor 88', 'RNA, Messenger', 'Signal Transduction'] | 18,250,418 | [['B01.050'], ['A11.251.210'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['G12.300'], ['C01.757.100.275', 'C01.861.375', 'C23.550.470.790.500.100.275'], ['G05.308'], ['D12.644.276.374.440.890.275', 'D12.776.467.374.440.890.275', 'D23.529.374.440.890.275'], ['D09.400.500', 'D09.698.718.450', 'D10.4... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cortically driven Fos induction in the striatum is amplified by local dopamine D2-class receptor blockade. | Dopamine D2-class receptors have been shown to control the excitability of striatal neurons in response to cortical activation. It has been unclear, however, whether such receptors could regulate the number of striatal neurons activated by cortical stimulation, and thus affect the population response of the striatum to... | ['Animals', 'Cerebral Cortex', 'Corpus Striatum', 'Dopamine Antagonists', 'Dopamine D2 Receptor Antagonists', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation', 'Haloperidol', 'Injections, Epidural', 'Oncogene Proteins v-fos', 'Picrotoxin', 'Rats', 'Rats, Sprague-Dawley', 'Sulpiride'] | 10,594,656 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['A08.186.211.200.885.287.249.487'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['D27.505.519.625.150.175.500', 'D27.505.696.577.150.175.500'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308'], ['D02.522.352.506'], ['E02.319.267.530.580.300'], ['D12.776.624... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana. | Filoviruses (Ebola and Marburg viruses) cause severe and often fatal haemorrhagic fever in humans and non-human primates. The US Centers for Disease Control identifies Ebola and Marburg viruses as 'category A' pathogens (defined as posing a risk to national security as bioterrorism agents), which has lead to a search f... | ['Animals', 'Antibodies, Monoclonal', 'Antibodies, Viral', 'Antigen-Antibody Complex', 'Complement C1q', 'Ebolavirus', 'Female', 'Geminiviridae', 'Gene Expression', 'Genetic Vectors', 'Hemorrhagic Fever, Ebola', 'Humans', 'Immunoglobulin G', 'Mice', 'Mice, Inbred BALB C', 'Phenotype', 'Plant Leaves', 'Recombinant Fusio... | 21,281,425 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ossified skeletal muscle angioma: report of two cases. | Ossifying skeletal muscle angiomas are relatively rare occurrences. The preoperative diagnosis is exceedingly difficult, although ossification may be reflected radiologically as a "Swiss cheese" appearance. Two patients are described whose skeletal muscle angiomas contained osseous tissue. The osseus tissue varied from... | ['Adult', 'Female', 'Forearm', 'Hemangioma', 'Humans', 'Muscular Diseases', 'Ossification, Heterotopic', 'Radiography'] | 6,420,620 | [['M01.060.116'], ['A01.378.800.585'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.651', 'C10.668.491'], ['C23.550.751'], ['E01.370.350.700']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Plasma androgenic activity in women with acne vulgaris and in healthy girls before, during and after puberty. | The possible relationship between plasma androgenic activity and acne vulgaris was investigated. Plasma testosterone and sex hormone binding globulin (SHBG) levels were determined in healthy girls during different stages of puberty, in healthy adult women and in women with acne vulgaris. Testosterone increase during pu... | ['Acne Vulgaris', 'Adolescent', 'Adult', 'Female', 'Humans', 'Puberty', 'Sex Hormone-Binding Globulin', 'Testosterone'] | 6,210,470 | [['C17.800.030.150', 'C17.800.794.111'], ['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.760', 'G08.686.841.374'], ['D12.776.124.790.223.800', 'D12.776.157.762', 'D12.776.377.715.182.800'], ['D04.210.500.054.079.429.824', 'D06.472.334.851.968.984']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Basilar artery narrowing and hyperparathyroidism: illustrative case. | A patient presenting with a pontine infarction caused by mid-basilar artery narrowing associated with hyperparathyroidism is described. The narrowing reversed with surgical removal of his parathyroid adenoma and normalization of his serum calcium. This patient's illness lends evidence to the role of calcium in cerebral... | ['Adenoma', 'Adult', 'Basilar Artery', 'Calcium', 'Cerebral Angiography', 'Humans', 'Hyperparathyroidism', 'Ischemic Attack, Transient', 'Male', 'Parathyroid Neoplasms', 'Vasoconstriction'] | 3,764,947 | [['C04.557.470.035'], ['M01.060.116'], ['A07.015.114.106'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C1... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acanthamoeba T4 genotype associated with keratitis infections in Tunisia. | Acanthamoeba keratitis (AK) is a sight-threatening infection. We report five cases of AK diagnosed from 2005 to 2009 in the Laboratory of Parasitology-Mycology at Habib Bourguiba Sfax Hospital, Tunisia. All were associated with improper care of contact lenses (rinsing of contact lenses with tap water and inappropriate ... | ['Acanthamoeba', 'Acanthamoeba Keratitis', 'Cluster Analysis', 'Contact Lenses', 'DNA, Protozoan', 'DNA, Ribosomal', 'Genotype', 'Humans', 'Molecular Sequence Data', 'Parasitology', 'Phylogeny', 'RNA, Ribosomal, 18S', 'Sequence Analysis, DNA', 'Tunisia'] | 23,052,779 | [['B01.046.500.100.075.080'], ['C01.610.300.125', 'C01.610.752.049.203', 'C11.204.564.112', 'C11.294.725.125'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E07.632.500.276'], ['D13.444.308.442'], ['D13.444.308.475'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.66... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Development of a diabetes diet-related quality-of-life scale. | OBJECTIVE: The purpose of this study was to assess the reliability and validity of the Diabetes Diet-Related Quality-of-Life (DDRQOL) scale, which is a measure of the influence of diet therapy on patients' quality of life (QOL).RESEARCH DESIGN AND METHODS: Patients with type 2 diabetes (n = 236) who were being treated ... | ['Diabetes Mellitus, Type 2', 'Diet, Diabetic', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Japan', 'Male', 'Patient Compliance', 'Patient Satisfaction', 'Quality of Life', 'Socioeconomic Factors'] | 15,161,774 | [['C18.452.394.750.149', 'C19.246.300'], ['E02.642.249.240', 'G07.203.650.240.240'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Associated skeletons of a new middle Triassic "Rauisuchia" from Brazil. | For more than 30 million years, in early Mesozoic Pangea, "rauisuchian" archosaurs were the apex predators in most terrestrial ecosystems, but their biology and evolutionary history remain poorly understood. We describe a new "rauisuchian" based on ten individuals found in a single locality from the Middle Triassic (La... | ['Animals', 'Bone and Bones', 'Brazil', 'Fossils', 'Paleontology', 'Reptiles', 'Species Specificity'] | 21,445,632 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['Z01.107.757.176'], ['I01.076.368.584.311'], ['H01.277.875', 'I01.076.368.584'], ['B01.050.150.900.833'], ['G16.824']] | ['Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
New insights into metabolic properties of marine bacteria encoding proteorhodopsins. | Proteorhodopsin phototrophy was recently discovered in oceanic surface waters. In an effort to characterize uncultured proteorhodopsin-exploiting bacteria, large-insert bacterial artificial chromosome (BAC) libraries from the Mediterranean Sea and Red Sea were analyzed. Fifty-five BACs carried diverse proteorhodopsin g... | ['Bacterial Proteins', 'Carotenoids', 'Chromosomes, Artificial, Bacterial', 'Cloning, Molecular', 'Conserved Sequence', 'Escherichia coli', 'Gene Library', 'Indian Ocean', 'Light', 'Mediterranean Sea', 'Molecular Sequence Data', 'Multigene Family', 'Operon', 'Oxidoreductases Acting on Sulfur Group Donors', 'Phylogeny',... | 16,008,504 | [['D12.776.097'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['A11.284.187.178.170', 'A11.284.187.190.170', 'A20.812.170', 'G05.360.162.178.170', 'G05.360.162.190.170', 'G05.360.337.249.170'], ['E05.393.220'], ['G02.111.570.580'], ['B03.440.450.425.325.300', 'B03.6... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Numerical simulation of blood flow in an anatomically-accurate cerebral venous tree. | Although many blood flow models have been constructed for cerebral arterial trees, few models have been reported for their venous counterparts. In this paper, we present a computational model for an anatomically accurate cerebral venous tree which was created from a computed tomography angiography (CTA) image. The topo... | ['Adult', 'Angiography', 'Brain', 'Cerebrovascular Circulation', 'Computer Simulation', 'Hemodynamics', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Models, Anatomic', 'Models, Cardiovascular', 'Reproducibility of Results', 'Tomography, X-Ray Computed'] | 22,949,055 | [['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A08.186.211'], ['G09.330.100.159'], ['L01.224.160'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['E05.599.395.161'], ['E05.318.370.725', 'E05.337.851', 'N05.715... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Effect of wheel-running during abstinence on subsequent nicotine-seeking in rats. | RATIONALE: Exercise appears to be a promising non-pharmacological treatment for nicotine addiction that may be useful for the vulnerable adolescent population.OBJECTIVES: The aim of this study is to determine if wheel-running, an animal model of aerobic exercise, during an abstinence period would decrease subsequent ni... | ['Aging', 'Animals', 'Behavior, Animal', 'Conditioning, Operant', 'Cues', 'Drug-Seeking Behavior', 'Extinction, Psychological', 'Male', 'Nicotine', 'Physical Conditioning, Animal', 'Rats', 'Rats, Sprague-Dawley', 'Reinforcement Schedule', 'Self Administration', 'Substance Withdrawal Syndrome'] | 23,371,488 | [['G07.345.124'], ['B01.050'], ['F01.145.113'], ['F02.463.425.179.509'], ['F02.463.425.234'], ['F01.145.342'], ['F02.463.425.770.232'], ['D03.132.760.570', 'D03.383.725.518'], ['G11.427.410.698.277.280'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['F02.463.425.770.644... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biomass Increases Go under Cover: Woody Vegetation Dynamics in South African Rangelands. | Woody biomass dynamics are an expression of ecosystem function, yet biomass estimates do not provide information on the spatial distribution of woody vegetation within the vertical vegetation subcanopy. We demonstrate the ability of airborne light detection and ranging (LiDAR) to measure aboveground biomass and subcano... | ['Biomass', 'Conservation of Natural Resources', 'Forestry', 'Forests', 'Humans', 'South Africa', 'Trees', 'Wood'] | 25,969,985 | [['G16.500.275.157.100', 'N06.230.124.100'], ['J01.256', 'N06.230.080'], ['J01.576.430'], ['G16.500.275.157.437', 'N06.230.124.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.175.735'], ['B01.650.915'], ['A18.450.500.500', 'J01.637.241.900']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Replication variants of the human inactive X chromosome. II. Frequency and replication rate relative to the other chromosomes of the complement. | Replication variants of the inactive X chromosome were investigated in lymphocytes from six donors by means of terminal BrdU or thymidine incorporation. There were interindividual differences in the incidence of particular variants. In endoreduplicated and tetraploid cells both allocyclic X chromosomes showed the same ... | ['Chromosome Aberrations', 'DNA Replication', 'Female', 'Humans', 'In Vitro Techniques', 'Lymphocytes', 'X Chromosome'] | 6,538,134 | [['C23.550.210', 'G05.365.590.175'], ['G02.111.225', 'G05.226'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['A11.284.187.865.982', 'G05.360.162.865.982']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aâ-induced microglial cell activation is inhibited by baicalin through the JAK2/STAT3 signaling pathway. | Baicalin has shown multiple neuroprotective biological activities, including antiapoptotic and anti-inflammatory functions in neurodegeneration diseases. However, whether baicalin can regulate Aâ-induced microglial activation or inhibit inflammatory cytokine secretion has not been confirmed. We demonstrated that baical... | ['Amyloid beta-Peptides', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Flavonoids', 'Humans', 'Janus Kinase 2', 'Mice', 'Mice, Transgenic', 'Microglia', 'Peptide Fragments', 'Random Allocation', 'STAT3 Transcription Factor', 'Signal Transduction'] | 24,219,385 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.725.124.200', 'D12.776.47... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Protective effects of magnesium sulfate against doxorubicin induced cardiotoxicity in rats. | AIMS: Clinical use of doxorubicin, an effective chemotherapeutic agent, has limited uses due to dose-dependent cardiac toxicity. It has been supposed that the production of free radicals and calcium ions overload can lead to cardiac toxicity. Magnesium is a cardioprotective drug which inhibits lipid peroxidation and re... | ['Animals', 'Antioxidants', 'Body Weight', 'Calcium', 'Cardiotoxicity', 'Doxorubicin', 'Electrocardiography', 'Free Radicals', 'Glutathione', 'Heart', 'Heart Ventricles', 'Ions', 'Magnesium Sulfate', 'Male', 'Muscle Contraction', 'Myocardium', 'Oxidative Stress', 'Oxygen', 'Rats', 'Rats, Wistar'] | 29,940,240 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C14.280.260', 'C23.550.161', 'C25.100.389', 'C26.733.266', 'G01.750.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative pharmacokinetics and pharmacodynamics of lorazepam, alprazolam and diazepam. | The contribution of differential absorption-distribution pharmacokinetics to drug activity can be partially determined by comparing simultaneous estimates of drug serum level with pharmacodynamic effects. In the present paper we have contrasted the effects of clinically equipotent doses of lorazepam, alprazolam, and di... | ['Adult', 'Alprazolam', 'Anti-Anxiety Agents', 'Benzodiazepines', 'Diazepam', 'Dose-Response Relationship, Drug', 'Drug Tolerance', 'Humans', 'Kinetics', 'Lorazepam', 'Male', 'Psychomotor Performance', 'Receptors, GABA-A'] | 2,863,843 | [['M01.060.116'], ['D03.633.100.079.080.030'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D03.633.100.079.080'], ['D03.633.100.079.080.070.216'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.992'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Benchtop Approach to the Location Specific Blood Brain Barrier Opening using Focused Ultrasound in a Rat Model. | Stereotaxic surgery is the gold standard for localized drug and gene delivery to the rodent brain. This technique has many advantages over systemic delivery including precise localization to a target brain region and reduction of off target side effects. However, stereotaxic surgery is highly invasive which limits its ... | ['Animals', 'Blood-Brain Barrier', 'Drug Delivery Systems', 'Laboratories', 'Microbubbles', 'Rats', 'Ultrasonic Waves'] | 32,597,853 | [['B01.050'], ['A07.035', 'A08.186.211.035'], ['E02.319.300'], ['J03.520', 'N02.278.487'], ['E07.553'], ['B01.050.150.900.649.313.992.635.505.700'], ['G01.750.770.776.891']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
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