Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Children's inequity aversion depends on culture: a cross-cultural comparison. | Recent work showed the presence of strong forms of inequity aversion in young children. When presented with an uneven number of items, children would rather tend to throw one item away than to distribute them unequally between two anonymous others. The current study examined whether or not this pattern is a universal p... | ['Child', 'Cross-Cultural Comparison', 'Decision Making', 'Female', 'Humans', 'Male', 'Resource Allocation', 'Socioeconomic Factors', 'Uganda', 'United States'] | 25,626,404 | [['M01.060.406'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.261.750'], ['I01.880.853.996', 'N01.824'], ['Z01.058.290.120.880'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Development of a simple and rapid immunochromatographic strip test for diarrhea-causative porcine rotavirus in swine stool. | A rapid and simple immunochromatography (IC) strip test, for specific detection of porcine rotavirus (PRV) in stool specimen, was developed. Monoclonal antibodies (mAbs) to the OSU strain of PRV have been produced in mice. Among them, two hybridoma clones that generate mAb-1 and mAb-2, respectively, specific for VP6 pr... | ['Animals', 'Antibodies, Monoclonal', 'Antibodies, Viral', 'Cell Line', 'Diarrhea', 'Feces', 'Immunoassay', 'Reagent Strips', 'Rotavirus', 'Rotavirus Infections', 'Sensitivity and Specificity', 'Swine', 'Swine Diseases'] | 17,644,198 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.251.210'], ['C23.888.821.214'], ['A12.459'], ['E05.478.566', 'E05.601.470'], ['D27.505.259.875.680', 'D27.720.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effects of selective serotonin reuptake inhibitors on platelet function in whole blood and platelet concentrates. | Several studies report that patients who are treated with selective serotonin reuptake inhibitors (SSRIs) for depression may have increased risk of bleeding, particularly from the gastrointestinal tract. This may be related to low intraplatelet serotonin concentrations. Several blood banks do not store platelets from d... | ['Adult', 'Blood Gas Analysis', 'Blood Platelets', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pilot Projects', 'Platelet Aggregation', 'Platelet Count', 'Platelet Membrane Glycoproteins', 'Platelet Transfusion', 'Serotonin', 'Serotonin Uptake Inhibitors', 'Thrombelastography'] | 22,273,511 | [['M01.060.116'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['G09.188.370.687', 'G09.188.390.600.64... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adherence in the CAPRISA 004 tenofovir gel microbicide trial. | High adherence is key to microbicide effectiveness. Here we provide a description of adherence interventions and the adherence rates achieved in the CAPRISA 004 Tenofovir gel trial. Adherence support for the before-and-after dosing strategy (BAT 24) was provided at enrolment and at each monthly study visit. This initia... | ['Adenine', 'Administration, Intravaginal', 'Adult', 'Anti-HIV Agents', 'Anti-Infective Agents, Local', 'Counseling', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Gels', 'HIV Infections', 'HIV-1', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Medication Adherence', 'Motivational Interviewing', 'Organophosp... | 24,643,315 | [['D03.633.100.759.138'], ['E02.319.267.120.500'], ['M01.060.116'], ['D27.505.954.122.388.077.088'], ['D27.505.954.122.187'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.318.372.500.750.249', 'N05.715.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Neonatal ventral hippocampus lesions disrupt extra-dimensional shift and alter dendritic spine density in the medial prefrontal cortex of juvenile rats. | Recent data showed that neonatal ventral hippocampus (VH) lesions, an approach used to model schizophrenia symptoms in rodents, produce premature deficits of working memory believed to be associated with early medial prefrontal cortex (mPFC) maldevelopment. This experiment expands the investigation of mPFC integrity in... | ['Age Factors', 'Animals', 'Animals, Newborn', 'Association Learning', 'Attention', 'Brain Mapping', 'Choice Behavior', 'Cues', 'Dendritic Spines', 'Discrimination Learning', 'Dominance, Cerebral', 'Hippocampus', 'Ibotenic Acid', 'Male', 'Maze Learning', 'Memory, Short-Term', 'Microinjections', 'Motivation', 'Nerve Net... | 18,490,183 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.050.282'], ['F02.463.425.069.296'], ['F02.830.104.214'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.785.373.346'], ['F02.463.425.234'], ['A08.675.256.200', 'A11.284.180.225.169', 'A11.671.240.169'], ['F02.463.425.2... | ['Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Survival is Better After Breast Conserving Therapy than Mastectomy for Early Stage Breast Cancer: A Registry-Based Follow-up Study of Norwegian Women Primary Operated Between 1998 and 2008. | BACKGROUND: Breast-conserving therapy (BCT) and mastectomy (MTX) has been considered to have a similar long-time survival. However, better survival in women undergoing BCT compared with MTX is found in two recent register studies from the United States. The purpose of this study was to compare survival after BCT and MT... | ['Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Lymphatic Metastasis', 'Mastectomy', 'Mastectomy, Segmental', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Staging', 'Norway', 'Proportional Hazards Models', 'Radiotherapy, Adjuvant', 'Registries... | 25,743,325 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['C04.6... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Absence of CD9 reduces endometrial VEGF secretion and impairs uterine repair after parturition. | In mammals, uterine epithelium is remodeled cyclically throughout adult life for pregnancy. Despite the expression of CD9 in the uterine epithelium, its role in maternal reproduction is unclear. Here, we addressed this issue by examining uterine secretions collected from patients undergoing fertility treatment and fert... | ['Adult', 'Animals', 'Cytokines', 'Endometrium', 'Epithelial Cells', 'Female', 'Humans', 'Male', 'Matrix Metalloproteinases', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Pregnancy', 'Recombinant Proteins', 'Tetraspanin 29', 'Uterus', 'Vascular Endothelial Growth Factor A'] | 24,736,431 | [['M01.060.116'], ['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A05.360.319.679.490'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480.525', 'D08.811.277.656.675.374.525'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.0... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cross-reaction of a minor variant of the a1 allotypic specificity with anti-a2 antibodies. | Certain samples of hare IgG can combine with cross-linked anti-a2 antisera prepared in the a3/a3 rabbit. This cross-reaction permitted the isolation, on hare IgG immunoadsorbent, of anti-a2 cross-reacting antibodies (anti-a2(Lv) antibodies). The binding of labeled rabbit a2 IgG to insolubilized anti-a2(Lv) antibodies i... | ['Antibodies, Anti-Idiotypic', 'Antigen-Antibody Reactions', 'Binding Sites, Antibody', 'Cross Reactions', 'Immune Sera', 'Immunoglobulin G', 'Immunosorbent Techniques', 'Isoantigens'] | 333,552 | [['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['G12.122'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['G12.122.281'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress. | Although c-Myc is essential for melanocyte development, its role in cutaneous melanoma, the most aggressive skin cancer, is only partly understood. Here we used the NrasQ61KINK4a-/- mouse melanoma model to show that c-Myc is essential for tumor initiation, maintenance, and metastasis. c-Myc-expressing melanoma cells we... | ['AMP-Activated Protein Kinases', 'Animals', 'Apoptosis', 'Cell Line, Tumor', 'Cell Survival', 'Cell Transformation, Neoplastic', 'Cyclin-Dependent Kinase Inhibitor p16', 'GTP Phosphohydrolases', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Melanocytes', 'Melanoma', 'Membrane Proteins', 'Mice', 'Mice, Inbred C5... | 29,440,228 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['D08.811.277.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative analysis of circulating plasma DNA as a tumor marker in thoracic malignancies. | BACKGROUND: Increased plasma DNA has been found in cancer patients and may have potential as a tumor marker. The objectives of this study were to develop a controlled, quantitative PCR (QPCR) assay to measure plasma DNA and then evaluate plasma DNA concentrations as a tumor marker in patients with thoracic malignancies... | ['Biomarkers, Tumor', 'DNA, Neoplasm', 'Esophageal Neoplasms', 'Humans', 'Lung Neoplasms', 'Plasma', 'Polymerase Chain Reaction', 'Prospective Studies', 'Reproducibility of Results', 'Thoracic Neoplasms'] | 15,539,466 | [['D23.101.140'], ['D13.444.308.425'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['E05.393.620.500'], ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Usefulness of Prophylactic Percutaneous Gastrostomy Placement in Patients with Head and Neck Cancer Treated with Chemoradiotherapy. | Chemoradiotherapy (CRT) has evolved as the preferred organ preservation strategy in the treatment of locally advanced head and neck cancer (HNC). This approach increases malnutrition, and thus, establishing a direct enteral feeding route is essential. To evaluate the usefulness of prophylactic percutaneous endoscopic g... | ['Adult', 'Aged', 'Chemoradiotherapy', 'Enteral Nutrition', 'Female', 'Gastrostomy', 'Humans', 'Intubation, Gastrointestinal', 'Male', 'Malnutrition', 'Middle Aged', 'Mouth Neoplasms', 'Nutritional Status', 'Otorhinolaryngologic Neoplasms', 'Prospective Studies', 'Time Factors'] | 26,487,063 | [['M01.060.116'], ['M01.060.116.100'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['E02.421.360', 'E02.642.500.360'], ['E04.210.496', 'E04.579.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.585.412', 'E05.497.412'], ['C18.654.521'], ['M01.060.116.630'], ['C04.588.443.591', 'C07.465.530'], ['G07.203.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Protein instability during HIC: describing the effects of mobile phase conditions on instability and chromatographic retention. | Hydrophobic interaction chromatography (HIC) is known to be potentially denaturing to proteins, but the effects of mobile phase conditions on chromatographic behavior are not well understood. In this study, we apply a model describing the effects of secondary protein unfolding equilibrium on chromatographic behavior, i... | ['Adsorption', 'Algorithms', 'Ammonium Sulfate', 'Animals', 'Calcium', 'Cattle', 'Chromatography, Gel', 'Computer Simulation', 'Deuterium Oxide', 'Edetic Acid', 'Hydrophobic and Hydrophilic Interactions', 'Lactalbumin', 'Mass Spectrometry', 'Models, Theoretical', 'Protein Denaturation', 'Proteins', 'Sepharose', 'Temper... | 16,444,741 | [['G01.030', 'G02.020'], ['G17.035', 'L01.224.050'], ['D01.625.062.374', 'D01.875.800.800.850.050'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.250'], ['L01.224.160'], ['D01.045.250.875.200', 'D01.248.497.158.459.650.200', 'D01.268.406.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Evaluation of systemic relaxin blood profiles in horses as a means of assessing placental function in high-risk pregnancies and responsiveness to therapeutic strategies. | Placental insufficiency is regarded as the primary factor contributing to late-term abortion and perinatal death of foals. Often when problems associated with late-term pregnancy in the horse are manifest the condition is well-advanced and therapeutic intervention may not be effective in rescuing the pregnancy. If a co... | ['Animals', 'Female', 'Horses', 'Placental Insufficiency', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy, Animal', 'Radioimmunoassay', 'Relaxin'] | 19,416,181 | [['B01.050'], ['B01.050.150.900.649.313.984.235.472'], ['C13.703.590.800'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['G08.686.784.769.498'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['D06.472.334.734.769', 'D06.472.699.715', 'D12.644.548.762']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-suicidal self-injury prevalence, course, and association with suicidal thoughts and behaviors in two large, representative samples of US Army soldiers. | BACKGROUND: Non-suicidal self-injury (NSSI) prospectively predicts suicidal thoughts and behaviors in civilian populations. Despite high rates of suicide among US military members, little is known about the prevalence and course of NSSI, or how NSSI relates to suicidal thoughts and behaviors, in military personnel.METH... | ['Adult', 'Age of Onset', 'Female', 'Humans', 'Male', 'Middle Aged', 'Military Personnel', 'Prevalence', 'Self-Injurious Behavior', 'Suicidal Ideation', 'Suicide', 'Suicide, Attempted', 'United States', 'Young Adult'] | 30,131,080 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.625'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['F01.145.126.980'], ['F01.145.126.980.875.149', 'I01... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A multivariate analysis of long-term stay in private practice psychotherapy. | Investigated the characteristics predictive of long-term stay in private practice psychotherapy in a population of 64 "long-term" clients (remained longer than 25 sessions, mean = 47 sessions) and 88 "short-term" clients (terminated before 25 sessions, mean = 7 sessions). Data consisted of T-scores on the intake MMPI a... | ['Humans', 'Insurance, Psychiatric', 'Long-Term Care', 'MMPI', 'Mental Disorders', 'Private Practice', 'Psychotherapy', 'Psychotropic Drugs', 'Regression Analysis'] | 6,777,401 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.658'], ['E02.760.476', 'N02.421.585.476'], ['F04.711.647.513.607'], ['F03'], ['N04.452.758.745'], ['F04.754'], ['D27.505.954.427.700'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750']] | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Simultaneous extraction of total RNA and peptides from tissues: application to tachykinins. | Methods for extraction and isolation of intact RNA are often laborious, time consuming, and preclude the direct analysis of peptides. Similarly, the conditions for extraction and isolation of peptides are unsuitable for the isolation of intact RNA. Thus, to study changes in the levels of neuropeptides and gene expressi... | ['Animals', 'Brain Chemistry', 'Chromatography, High Pressure Liquid', 'Female', 'Kidney', 'Liver', 'Male', 'Methods', 'Peptides', 'Polymerase Chain Reaction', 'RNA', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord', 'Substance P', 'Tachykinins'] | 7,536,324 | [['B01.050'], ['G02.111.150', 'G03.185'], ['E05.196.181.400.300'], ['A05.810.453'], ['A03.620'], ['E05.581'], ['D12.644'], ['E05.393.620.500'], ['D13.444.735'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A08.186.854'], ['D12.644.276.812.900.866', 'D12.644.400.800.750... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incomplete muscle activation after training with electromyostimulation. | Training with voluntary or electromyostimulation (EMS)-evoked eccentric contractions should produce complete muscle activation, since EMS and eccentric contractions preferentially recruit large motor units. Subjects (22 women ages 18-40) were randomly assigned to a voluntary (VOL; n = 8), EMS (n = 8), or control group.... | ['Adolescent', 'Adult', 'Electric Stimulation', 'Female', 'Humans', 'Muscle Contraction', 'Muscle, Skeletal', 'Physical Education and Training', 'Volition'] | 9,615,868 | [['M01.060.057'], ['M01.060.116'], ['E05.723.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['I02.233.543'], ['F02.463.902']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Congenital heart defects in Sotos sequence. | Of 10 patients with typical Sotos sequence, 5 had various congenital heart defects. They included 2 patients with secundum atrial septal defect, and one patient each with patent ductus arteriosus with mitral valve regurgitation, tricuspid atresia plus pulmonary atresia, and ventricular septal defect. Increases of head ... | ['Anthropometry', 'Child, Preschool', 'Female', 'Gigantism', 'Head', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Karyotyping', 'Male'] | 3,565,472 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.060.406.448'], ['C05.116.099.492', 'C05.116.132.479', 'C19.700.355.528'], ['A01.456'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Liver biopsy pathology in human immunodeficiency virus infection. | OBJECTIVES: To determine the hepatic changes in patients with human immunodeficiency virus (HIV) infection in Dublin and to assess the usefulness of liver biopsy in this condition.DESIGN: A consecutive series of liver biopsies was examined retrospectively and correlated with clinical findings.METHODS: A histological re... | ['Acute Disease', 'Adult', 'Aged', 'Biopsy', 'Female', 'HIV Infections', 'Hepatitis', 'Humans', 'Liver', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Retrospective Studies'] | 9,585,031 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Report of a family segregating mutations in both the APC and MSH2 genes: juvenile onset of colorectal cancer in a double heterozygote. | BACKGROUND AND AIMS: Mutations in DNA mismatch repair genes are associated with high risk of digestive malignancies [hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome]; mutations of APC and MYH are associated with classic and attenuated familial adenomatous polyposis (FAP). Although the early onset of ... | ['Adolescent', 'Adult', 'Age of Onset', 'Aged', 'Alleles', 'Colorectal Neoplasms', 'DNA, Neoplasm', 'Family', 'Female', 'Genes, APC', 'Genetic Predisposition to Disease', 'Heterozygote', 'Humans', 'Male', 'Middle Aged', 'MutS Homolog 2 Protein', 'Mutation', 'Pedigree', 'Polymerase Chain Reaction', 'Young Adult'] | 18,629,513 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D13.444.308.425'], ['F01.829.263', 'I01.8... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Body fluid spaces in patients on CAPD. | Total body water (TBW) and extracellular water (ECW) were determined in 9 CAPD patients on treatment from 5 to 14 months (mean 8.6 months). The mean value of TBW was normal and directly correlated to body weight, but TBW was abnormally distributed between extracellular and intracellular space. ECW volume was significan... | ['Adult', 'Aged', 'Body Fluids', 'Body Water', 'Body Weight', 'Extracellular Space', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Peritoneal Dialysis', 'Peritoneal Dialysis, Continuous Ambulatory'] | 6,735,501 | [['M01.060.116'], ['M01.060.116.100'], ['A12.207'], ['A12.207.200'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A10.082.500', 'A11.284.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. | Site-directed mutagenesis and Laue diffraction data to 2.5 A resolution were used to solve the structures of two sequential intermediates formed during the catalytic actions of isocitrate dehydrogenase. Both intermediates are distinct from the enzyme-substrate and enzyme-product complexes. Mutation of key catalytic res... | ['Binding Sites', 'Catalysis', 'Computer Graphics', 'Crystallography, X-Ray', 'Isocitrate Dehydrogenase', 'Isocitrates', 'Kinetics', 'Mutagenesis, Site-Directed', 'NADP', 'Protein Conformation'] | 7,761,851 | [['G02.111.570.120'], ['G02.130'], ['L01.224.108', 'L01.296.110'], ['E05.196.309.742.225'], ['D08.811.682.047.820.475'], ['D02.241.081.901.434.498'], ['G01.374.661', 'G02.111.490'], ['E05.393.420.601.575'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749'], ['G02.111.570.820.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Identification of methylguanine methyltransferase polymorphisms as genetic markers of individual susceptibility to therapy-related myeloid neoplasms. | PURPOSE: Myelodysplastic syndromes (MDS) are pre-leukaemic haematopoietic stem cell disorders. Among them, 10-20% occur after chemotherapy and/or radiotherapy, and are called 'therapy-related MDS' (t-MDS). The aim of this study was to identify genetic markers in t-MDS.METHODS: A prospective cohort of 59 MDS patients (3... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chemoradiotherapy', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Linkage Disequilibrium', 'Male', 'Middle Aged', 'Myelodysplastic Syndromes', 'Neoplasms', 'O(6)-Methylguanine-DNA Methyltransferase', 'Polymorphism, Single Nucleotide', 'Pr... | 24,238,921 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.500'], ['M01.060.116.630'], ['C15.378.190.625'], ['C04'], ['D08.811.913.555.500.800.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Use of the tac promoter and lacIq for the controlled expression of Zymomonas mobilis fermentative genes in Escherichia coli and Zymomonas mobilis. | The Zymomonas mobilis genes encoding alcohol dehydrogenase I (adhA), alcohol dehydrogenase II (adhB), and pyruvate decarboxylase (pdc) were overexpressed in Escherichia coli and Z. mobilis by using a broad-host-range vector containing the tac promoter and the lacIq repressor gene. Maximal IPTG (isopropyl-beta-D-thiogal... | ['Alcohol Dehydrogenase', 'Base Sequence', 'Cloning, Molecular', 'Conjugation, Genetic', 'DNA, Bacterial', 'Escherichia coli', 'Fermentation', 'Gene Expression Regulation, Bacterial', 'Gene Expression Regulation, Enzymologic', 'Genes, Bacterial', 'Isoenzymes', 'Isopropyl Thiogalactoside', 'Kinetics', 'Molecular Sequenc... | 1,429,459 | [['D08.811.682.047.820.250'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['G05.728.200'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.158.249', 'G03.191.249'], ['G05.308.300'], ['G05.308.320'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparative study of state-of-the-art myoelectric controllers for multigrasp prosthetic hands. | A myoelectric controller should provide an intuitive and effective human-machine interface that deciphers user intent in real-time and is robust enough to operate in daily life. Many myoelectric control architectures have been developed, including pattern recognition systems, finite state machines, and more recently, p... | ['Activities of Daily Living', 'Adult', 'Algorithms', 'Artificial Limbs', 'Electromyography', 'Hand', 'Humans', 'Movement', 'Muscle Contraction', 'Muscle, Skeletal', 'Posture', 'Prosthesis Design', 'Robotics', 'Signal Processing, Computer-Assisted', 'Task Performance and Analysis', 'User-Computer Interface', 'Young Adu... | 25,803,683 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['G17.035', 'L01.224.050'], ['E07.695.050', 'E07.858.082.050', 'E07.858.442.050'], ['E01.370.405.255', 'E01.370.530.255'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['G11.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Indust... | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
Enhanced Angiotensin II type 1 receptor expression in leukocytes of patients with chronic kidney disease. | Previously, we demonstrated increased Angiotensin II type I receptor expression in leukocytes from patients with untreated, but not in treated, essential hypertension (essential hypertension). We hypothesized that the Angiotensin II AT1 receptor is also increased in leukocytes from patients with chronic kidney disease,... | ['Angiotensin II Type 1 Receptor Blockers', 'Blood Pressure', 'Chronic Disease', 'Female', 'Gene Expression Regulation', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Kidney Diseases', 'Leukocytes', 'Male', 'Middle Aged', 'Receptor, Angiotensin, Type 1', 'Renin-Angiotensin System'] | 21,640,098 | [['D27.505.519.162.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.550.291.500'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['C12.777.419', 'C13.351.968.419'], ['A11.118.637', 'A15.145.229.637', 'A15.382.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dyotropic rearrangement facilitated proximal functionalization and oxidative removal of angular methyl groups: efficient syntheses of 23'-deoxy cephalostatin 1 analogues. | Oxidative functionalization (or removal) of a steroidal C18 methyl group is possible using a previously unknown dyotropic rearrangement of a seven-membered fused C-ring lactone to a 6-ring spiro lactone. Spiroketal equilibration led to the 23-deoxy South analogue of cephalostatin 1 (1) in only 12 steps (23% overall yie... | ['Oxidation-Reduction', 'Phenazines', 'Spiro Compounds', 'Spironolactone', 'Stereoisomerism', 'Steroids'] | 11,971,687 | [['G02.700', 'G03.295.531'], ['D03.633.300.704'], ['D02.455.426.779', 'D04.711'], ['D02.540.679', 'D04.210.500.745.745.855'], ['G02.607.445.682'], ['D04.210.500']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Appearance of erythrocyte-like globules in the mouse visceral yolk sac endodermal cells on embryonic day 12, with special reference to blood islands. | The mouse visceral yolk sac (VYS) is widely known to play an important role as erythropoietic tissue during embryonic periods. Mouse VYS from embryonic days 9 to 12 was examined by light microscopy, electron microscopy and histochemical analysis with benzidine to detect the presence of hemoglobin with special reference... | ['Animals', 'Embryo, Mammalian', 'Endoderm', 'Erythrocytes', 'Female', 'Gestational Age', 'Male', 'Mice', 'Pregnancy', 'Yolk Sac'] | 12,801,082 | [['B01.050'], ['A16.254'], ['A16.504.407'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.992.635.505.500'], ['G08.686.784.769'], ['A10.615.284.981', 'A16.254.750.981', 'A16.331.800']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A functional spiking-neuron model of activity-silent working memory in humans based on calcium-mediated short-term synaptic plasticity. | In this paper, we present a functional spiking-neuron model of human working memory (WM). This model combines neural firing for encoding of information with activity-silent maintenance. While it used to be widely assumed that information in WM is maintained through persistent recurrent activity, recent studies have sho... | ['Action Potentials', 'Calcium', 'Humans', 'Models, Biological', 'Neuronal Plasticity', 'Neurons'] | 32,516,337 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['G11.561.638'], ['A08.675', 'A11.671']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spot scanning proton therapy for malignancies of the base of skull: treatment planning, acute toxicities, and preliminary clinical outcomes. | PURPOSE: To describe treatment planning techniques and early clinical outcomes in patients treated with spot scanning proton therapy for chordoma or chondrosarcoma of the skull base.METHODS AND MATERIALS: From June 2010 through August 2011, 15 patients were treated with spot scanning proton therapy for chordoma (n=10) ... | ['Adult', 'Aged', 'Chondrosarcoma', 'Chordoma', 'Female', 'Humans', 'Male', 'Middle Aged', 'Organ Sparing Treatments', 'Organs at Risk', 'Proton Therapy', 'Radiation Injuries', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Intensity-Modulated', 'Relative Biological Effectiveness', 'S... | 25,304,948 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.450.565.280', 'C04.557.450.795.300'], ['C04.557.465.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.674'], ['A01.635'], ['E02.815.250.500'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E02.815.639... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Repositioning errors in measurement of vertebral attenuation values by computed tomography. | Difficulty in repositioning makes a major contribution to reproducibility errors in measurements of bone mineral by computed tomography (CT). The magnitude of measurement variations arising from incremental movements in each of three directions of displacement and two directions of rotation were investigated using two ... | ['Adult', 'Aged', 'Humans', 'Lumbar Vertebrae', 'Male', 'Minerals', 'Posture', 'Reference Values', 'Rotation', 'Tomography, X-Ray Computed'] | 6,850,211 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['D01.578'], ['G11.427.695'], ['E05.978.810'], ['G01.482.703'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Formation of gamma-glutamycyst(e)ine in vivo is catalyzed by gamma-glutamyl transpeptidase. | These studies indicate that gamma-glutamylcyst(e)ine, found in the urine of a patient with gamma-glutamyl transpeptidase deficiency and also in the urine of experimental animals injected with glutathione or with inhibitors of gamma-glutamyl transpeptidase, is formed by the action of gamma-glutamyltranspeptidase. The ev... | ['Animals', 'Cysteine', 'Dipeptides', 'Glutamates', 'Glutathione', 'Humans', 'Indicators and Reagents', 'Kidney', 'Mice', 'Pancreas', 'Pyridines', 'gamma-Glutamyltransferase'] | 6,114,489 | [['B01.050'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D12.644.456.345'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['A03.734'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liver-enriched Genes are Associated with the Prognosis of Patients with Hepatocellular Carcinoma. | Tissue-enriched genes are highly expressed in one particular tissue type and represent distinct physiological processes. The dynamic profile of tissue-enriched genes during tumorigenesis and progression remains largely unstudied. Here, we identified tissue-enriched genes from 12 tissue types based on RNA sequencing dat... | ['Adult', 'Aged', 'Carcinogenesis', 'Carcinoma, Hepatocellular', 'Databases, Genetic', 'Disease-Free Survival', 'Female', 'Gene Expression Regulation, Neoplastic', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Liver', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Proteins', 'Organ Specificity', 'Prognosis',... | 30,046,116 | [['M01.060.116'], ['M01.060.116.100'], ['C04.697.098', 'C23.550.727.098'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.... | ['Named Groups [M]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Region-specific genetic heterogeneity of HBB mutation distribution in South-Western Greece. | beta-Thalassemia (beta-thal), is caused by reduced or absent synthesis of beta-globin chains resulting in impaired erythropoiesis. It is the most common single gene defect disease in Greece, with heterozygous rates reaching, on average, 8% in the general population. Here, we performed molecular analyses on 199 unrelate... | ['DNA Mutational Analysis', 'Female', 'Gene Frequency', 'Genetic Counseling', 'Genetic Heterogeneity', 'Genetic Testing', 'Geography', 'Greece', 'Humans', 'Male', 'Mutation', 'Prevalence', 'beta-Globins', 'beta-Thalassemia'] | 20,642,331 | [['E05.393.760.700.300'], ['G05.330'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['G05.365.331'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['H01.277.500'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['E05.318.308.985.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Influence of Substrate Concentration on the Culturability of Heterotrophic Soil Microbes Isolated by High-Throughput Dilution-to-Extinction Cultivation. | The vast majority of microbes inhabiting oligotrophic shallow subsurface soil environments have not been isolated or studied under controlled laboratory conditions. In part, the challenges associated with isolating shallow subsurface microbes may persist because microbes in deeper soils are adapted to low nutrient avai... | ['Actinobacteria', 'Alphaproteobacteria', 'Arizona', 'Bacteriological Techniques', 'Centrifugation', 'Culture Media', 'Forests', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Soil Microbiology'] | 31,996,418 | [['B03.510.024', 'B03.510.460.400.400.049'], ['B03.660.050'], ['Z01.107.567.875.760.100'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E05.181'], ['D27.720.470.305', 'E07.206'], ['G16.500.275.157.437', 'N06.230.124.343'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['H01.158.273.540.274.555', ... | ['Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Recycling and reuse of wastewater from a new-developed community using sand filtration, ultrafiltration, and ozonation. | In this study, the pilot apparatus combined with sand filtration, ozonation and ultrafiltration was established. Wastewater from the secondary treatment effluent in the new-developed community was taken as the sample for looking into the feasibility of domestic wastewater reuse and recycling. The test results by sand f... | ['Conservation of Natural Resources', 'Cost Control', 'Costs and Cost Analysis', 'Filtration', 'Oxidants, Photochemical', 'Ozone', 'Silicon Dioxide', 'Water Pollutants', 'Water Purification'] | 14,524,686 | [['J01.256', 'N06.230.080'], ['N03.219.151.160'], ['N03.219.151'], ['E05.196.454', 'G01.280', 'G02.263'], ['D27.720.642.631', 'D27.888.569.540.631'], ['D01.362.670.600'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['D27.888.284.903'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mortality and hospitalisation costs of rheumatic fever and rheumatic heart disease in New Zealand. | AIMS: To estimate the annual mortality and the cost of hospital admissions for acute rheumatic fever (ARF) and rheumatic heart disease (RHD) for New Zealand residents.METHODS: Hospital admissions in 2000-2009 with a principal diagnosis of ARF or RHD (ICD9_AM 390-398; ICD10-AM I00-I099) and deaths in 2000-2007 with ... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Hospital Costs', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'New Zealand', 'Rheumatic Fever', 'Rheumatic Heart Disease', 'Young Adult'] | 22,494,452 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.639.760.747', 'Z01.678.100.747'], ['C01.150.252.410.890.731', 'C05.550.114.843', 'C05.799... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Estimating yields of salt- and water-stressed forages with remote sensing in the visible and near infrared. | In arid irrigated regions, the proportion of crop production under deficit irrigation with poorer quality water is increasing as demand for fresh water soars and efforts to prevent saline water table development occur. Remote sensing technology to quantify salinity and water stress effects on forage yield can be an imp... | ['Agriculture', 'Medicago sativa', 'Plant Leaves', 'Plant Physiological Phenomena', 'Plant Transpiration', 'Salts', 'Spectrophotometry, Ultraviolet', 'Spectroscopy, Near-Infrared', 'Time Factors', 'Triticum', 'Water'] | 16,738,391 | [['J01.040'], ['B01.650.940.800.575.912.250.401.590.500'], ['A18.024.812'], ['G15'], ['G15.713'], ['D01.786'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['E01.370.350.750', 'E05.196.867.851'], ['G01.910.857'], ['B01.650.940.800.575.912.250.822.918'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Outcome of adults with acute lymphocytic leukemia in second or subsequent complete remission. | The outcome of adults with acute lymphocytic leukemia (ALL) who achieve a complete response (CR) on salvage therapy is thought to be poor, but not previously analyzed. To define the course of adult ALL post CR on salvage therapy and the effects of pretreatment factors on prognosis. One hundred seventy-two adults with A... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Humans', 'Middle Aged', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Prognosis', 'Remission Induction', 'Risk Factors', 'Salvage Therapy', 'Survival Analysis', 'Treatment Outcome', 'Young Adult'] | 20,078,325 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.337.428.600', 'C15.604.515.560.600', 'C20.683.515.528.600'], ['E01.789'], ['E02.860'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The surgical case of a 34-year-old female patient with a metastatizing double colon tumor with different histological structure, causing mechanical obstruction]. | We would like to present the case of a young woman (age 34) who was admitted to our department due to unbearable colicky pain, which started one week prior to her hospitalization. Examinations revealed mechanical obstruction, which is very unusual in her age without surgical history. During emergency surgery, we found ... | ['Adenocarcinoma', 'Adult', 'Anastomosis, Surgical', 'Antineoplastic Combined Chemotherapy Protocols', 'Chemotherapy, Adjuvant', 'Colectomy', 'Colon, Sigmoid', 'Female', 'Humans', 'Ileum', 'Intestinal Obstruction', 'Neoplasms, Multiple Primary', 'Neuroendocrine Tumors', 'Peritoneal Neoplasms', 'Positron-Emission Tomogr... | 24,747,403 | [['C04.557.470.200.025'], ['M01.060.116'], ['E04.035'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186.170', 'E02.319.170'], ['E04.210.219'], ['A03.556.124.526.356.668', 'A03.556.249.249.356.668'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['C06.4... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1. | Engrailed1 and Engrailed2 (En1 and En2) are two developmental genes of the homeogene family expressed in the developing midbrain. En1 and, to a lesser degree, En2 also are expressed in the adult substantia nigra (SN) and ventral tegmental area (VTA), two dopaminergic (DA) nuclei of the ventral midbrain. In an effort to... | ['Animals', 'Cell Count', 'Cell Death', 'Dopamine', 'Female', 'Genetic Carrier Screening', 'Homeodomain Proteins', 'Male', 'Mesencephalon', 'Mice', 'Mice, Neurologic Mutants', 'Motor Activity', 'Nerve Tissue Proteins', 'Survival Analysis'] | 17,267,560 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.146'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E01.370.225.562.250', 'E05.200.562.250', 'E05.393.435.250', 'N02.421.308.200', 'N02.421.726.233.221.250'], ['D12.776.260.400'], ['A08.186.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Generic, simple risk stratification model for heart valve surgery. | BACKGROUND: Heart valve surgery has an associated in-hospital mortality rate of 4% to 8%. This study aims to develop a simple risk model to predict the risk of in-hospital mortality for patients undergoing heart valve surgery to provide information to patients and clinicians and to facilitate institutional comparisons.... | ['Cardiac Surgical Procedures', 'Databases, Factual', 'Heart Valves', 'Hospital Mortality', 'Humans', 'Knowledge Bases', 'Models, Statistical', 'Prognosis', 'Risk Assessment', 'Risk Factors'] | 15,998,680 | [['E04.100.376', 'E04.928.220'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['A07.541.510'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.050.375.480', 'L01.313.500.750.300.550'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Cardiovascular disease, osteoporosis and risk of fracture]. | A 60-year-old man, who did administrative work, consulted for evaluation of the presence of osteoporosis. He smoked ten cigarettes a day and drank alcohol occasionally. Eight years ago he suffered a Colle's fracture in his right arm after an incidental fall, which resolved without complications. His mother had a hip fr... | ['Bone Density Conservation Agents', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Osteoporosis', 'Osteoporotic Fractures', 'Practice Guidelines as Topic', 'Risk'] | 21,798,531 | [['D27.505.696.242'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['C05.116.198.579', 'C18.452.104.579'], ['C26.404.545'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E05.318.740.600.800', 'G17.680.750', 'N... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Time course of preferential motor unit loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. | Electromyographical analyses of pre-symptomatic motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS) have yielded contradictory findings as to the onset and time course. We recorded hindlimb muscle and motor unit isometric forces to determine motor unit number and size througho... | ['Amyotrophic Lateral Sclerosis', 'Animals', 'Axons', 'Cell Death', 'Cell Size', 'Disease Models, Animal', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Transgenic', 'Motor Neurons', 'Muscle Contraction', 'Muscle Fibers, Fast-Twitch', 'Muscle Fibers, Slow-Twitch', 'Muscle Strength', 'Muscle, Skeletal', 'Nerve Degeneration... | 17,766,128 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G04.146'], ['G04.325'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A longitudinal study of cerebral blood flow over the first 30 months. | To investigate prospectively the development of cerebral perfusion during infancy, serial quantitative measurements of cerebral blood flow (CBF) volume were performed in two healthy children from birth up to the age of 30 mo. A total of 28 CBF volume measurements were done in either of the children. Absolute flows were... | ['Adolescent', 'Blood Circulation Time', 'Blood Flow Velocity', 'Brain', 'Cerebrovascular Circulation', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Longitudinal Studies', 'Male', 'Reference Values', 'Time Factors'] | 19,668,104 | [['M01.060.057'], ['E01.370.370.120'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A08.186.211'], ['G09.330.100.159'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.85... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional characterization of the Shigella dysenteriae heme ABC transporter. | The heme ATP binding cassette (ABC) transporter, ShuUV, of Shigella dysenteriae has been incorporated into proteoliposomes. Functional characterization of ShuUV revealed that ATP hydrolysis and transport of heme from the periplasmic binding protein, ShuT, to the cytoplasmic binding protein, ShuS, are coupled. Site-dire... | ['ATP-Binding Cassette Transporters', 'Adenosine Triphosphate', 'Bacterial Proteins', 'Biological Transport', 'Heme', 'Histidine', 'Models, Biological', 'Mutagenesis, Site-Directed', 'Protein Binding', 'Protein Structure, Secondary', 'Shigella dysenteriae'] | 18,616,281 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.776.097'], ['G03.143'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Host habitat patchiness and the distance decay of similarity among gastro-intestinal nematode communities in two species of Mastomys (southeastern Senegal). | Beta-diversity, or how species composition changes with geographical distance, has seldom been studied for different habitats. We present here quantitative estimates of the relationship between geographic distance and similarity of parasitic nematode communities in two closely related rodent host species that live in h... | ['Animals', 'Demography', 'Ecosystem', 'Host-Parasite Interactions', 'Murinae', 'Nematoda', 'Population Density', 'Senegal'] | 17,351,796 | [['B01.050'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['G16.500.275.157', 'N06.230.124'], ['G16.527.200.400'], ['B01.050.150.900.649.313.992.635.505'], ['B01.050.500.500.294'], ['N01.224.600', 'N06.850.505.400.600'], ['Z01.058.290.190.710']] | ['Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Biological rhythms and depression]. | Circadian rhythms are found in all living organisms, and represent a physiological correlate of the geophysical rhythm of day and night. These rhythms are endogenous in nature, driven by a pacemaker in the hypothalamus, and synchronized to the 24-hour day. Many of the symptoms of affective illness can be considered in ... | ['Antidepressive Agents', 'Arousal', 'Bipolar Disorder', 'Circadian Rhythm', 'Depressive Disorder', 'Humans', 'Light', 'Seasons', 'Sleep Deprivation'] | 2,431,475 | [['D27.505.954.427.700.122'], ['F02.830.104', 'G11.561.035'], ['F03.084.500'], ['G07.180.562.190'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['C10... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Defunctioning loop ileostomy for pelvic anastomoses: predictors of morbidity and nonclosure. | OBJECTIVE: The aim of this study was to determine the morbidity of a defunctioning loop ileostomy and the subsequent closure rate, and to identify the predictors of complications and nonclosure of stoma.DESIGN: This study is a retrospective review of a single-institution experience.PATIENTS: All patients who underwent ... | ['Adolescent', 'Adult', 'Aged', 'Anastomosis, Surgical', 'Anastomotic Leak', 'Child', 'Female', 'Humans', 'Ileostomy', 'Ileum', 'Intestine, Large', 'Logistic Models', 'Male', 'Middle Aged', 'Postoperative Complications', 'Reoperation', 'Retrospective Studies', 'Risk Factors', 'Treatment Failure', 'Wound Closure Techniq... | 22,228,160 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.035'], ['C23.550.767.071'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E04.579.338.508'], ['A03.556.124.684.249', 'A03.556.249.124'], ['A03.556.124.526', 'A03.556.249.249'], ['E05.318.740.500.525', 'E05.318.740.600... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Restoring In Vivo-Like Membrane Lipidomics Promotes Exosome Trophic Behavior from Human Placental Mesenchymal Stromal/Stem Cells. | Human mesenchymal stem cells (hMSCs) are an effective tool in regenerative medicine notably for their intrinsic plentiful paracrine activity rather than differentiating properties. The hMSC secretome includes a wide spectrum of regulatory and trophic factors, encompassing several naked molecules as well as different ki... | ['Endoplasmic Reticulum', 'Exosomes', 'Female', 'Humans', 'Lipids', 'Mesenchymal Stem Cells', 'Placenta', 'Pregnancy'] | 29,562,775 | [['A11.284.430.214.190.875.248'], ['A11.284.295.588.750', 'A11.284.430.214.190.875.190.880.495'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['A11.329.830.500', 'A11.872.590.500'], ['A16.710'], ['G08.686.784.769']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts): report of 2 cases. | Clear cell sarcoma of tendons and aponeuroses (CCSTA, malignant melanoma of soft parts), first described by Enzinger in 1965, is a rare and slow-growing soft tissue tumor mainly affecting the extremities of young adults. The tumor is believed to be a tumor of melanocyte, although its histogenesis is not definitely esta... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Male', 'Melanoma', 'Soft Tissue Neoplasms', 'Tendons'] | 2,621,435 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['C04.588.839'], ['A02.880']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes. | The activation of Janus protein tyrosine kinases (JAKs) and signal transducer and activator of transcription (STAT) proteins by interleukin (IL)-2, the T cell antigen receptor (TCR) and interferon (IFN) alpha was explored in human peripheral blood-derived T cells and the leukemic T cell line Kit225. An IL-2-induced inc... | ['Base Sequence', 'DNA-Binding Proteins', 'Enzyme Activation', 'Humans', 'Interferon-alpha', 'Interleukin-2', 'Janus Kinase 1', 'Molecular Sequence Data', 'Oligodeoxyribonucleotides', 'Phosphorylation', 'Protein-Tyrosine Kinases', 'Receptors, Antigen, T-Cell', 'Receptors, IgG', 'Signal Transduction', 'T-Lymphocytes', '... | 7,988,557 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.260'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.250'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Application of surfactant assisted dispersive liquid-liquid microextraction for sample preparation of chlorophenols in water samples. | A simple, rapid, and efficient method, based on surfactant assisted dispersive liquid-liquid microextraction (SA-DLLME), followed by high performance liquid chromatography (HPLC) has been developed for the extraction and determination of chlorophenols as model compounds in environmental water samples. A conventional ca... | ['Cetrimonium', 'Cetrimonium Compounds', 'Chemical Fractionation', 'Chlorophenols', 'Chromatography, High Pressure Liquid', 'Environmental Monitoring', 'Hydrogen-Ion Concentration', 'Solvents', 'Surface-Active Agents', 'Water Pollutants, Chemical'] | 20,875,589 | [['D02.092.877.883.111.500', 'D02.675.276.190.500'], ['D02.092.877.883.111', 'D02.675.276.190'], ['E05.196.155'], ['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['E05.196.181.400.300'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G02.300'], ['D27.720.844'], ['D27.720.877'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Adapting the IDEAL Framework and Recommendations for medical device evaluation: A modified Delphi survey. | INTRODUCTION: Current regulatory systems for medical device marketing approval lack adequate requirements for evidence of safety and efficacy. The Total Product Life Cycle (TPLC) concept, with clinical use and marketing expanding as evidence develops, has won support, but lacks a template to define evidence requirement... | ['Delphi Technique', 'Equipment and Supplies', 'Humans', 'Informed Consent', 'Surveys and Questionnaires'] | 26,876,957 | [['L01.906.197'], ['E07'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Investigations on health-related properties of two sepiolite samples. | Published i.p. injection studies have shown different biological behavior of different sepiolite samples. There was no evidence for carcinogenic potential of sepiolite from Vicalvaro, Spain, whereas a high tumor incidence was reported for sepiolite from Finland. The low biological activity of the sepiolite from Vicalva... | ['Administration, Inhalation', 'Animals', 'Biodegradation, Environmental', 'Female', 'Lung Diseases', 'Magnesium Silicates', 'Microscopy, Electron', 'Organ Size', 'Particle Size', 'Rats', 'Rats, Wistar'] | 9,400,699 | [['E02.319.267.050'], ['B01.050'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['C08.381'], ['D01.524.500', 'D01.578.725.500', 'D01.837.725.700.760.535'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['G02.712'], ['B01.050.150.900.649.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Possible factors influencing the immunoglobulin G concentration in swine colostrum. | The immunoglobulin (Ig) G concentration in swine colostrum was determined by the single radial immunodiffusion method, using 157 samples collected from farm-raised sows in the Yamaguchi Prefecture of Japan during 1976 and 1977. The mean IgG value was 53.03 mg/ml, and the maximum and minimum values were 101.39 mg/ml and... | ['Age Factors', 'Animals', 'Breeding', 'Classical Swine Fever Virus', 'Colostrum', 'Female', 'Immunoglobulin G', 'Mammary Glands, Animal', 'Seasons', 'Swine', 'Transmissible gastroenteritis virus', 'Vaccination'] | 6,254,410 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['E05.820.150', 'G05.090'], ['B04.820.578.344.700.125'], ['A12.200.194'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['A10.336.482', 'A13.589'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.1... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stability of radiothyroxine plasma disappearance curve despite catharsis and unblocked thyroidal uptake of radioiodide. | Plasma radioactivity was measured over 21 days after an intravenous injection of 50 muCi of 125I-T4 in eight normal men. No thyroid-blocking medication was given. Four subjects (castor oil group) received 30 ml of castor oil on each of Days 13, 14, and 15, while the other four subjects (control group) were studied with... | ['Adult', 'Cathartics', 'Humans', 'Iodine', 'Iodine Radioisotopes', 'Male', 'Thyroid Gland', 'Thyroxine'] | 1,271,113 | [['M01.060.116'], ['D27.505.954.483.396'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['A06.300.900'], ['D06.472.931.812', 'D12.125.072.050.767']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of caponization and different exogenous androgen on the bone characteristics of male chickens. | The effects of caponization and androgen implantation on the bone characteristics of male chickens were evaluated. Healthy Single Comb White Leghorn cockerels were caponized or sham operated (sham) at 12 wk old. Sixteen birds from each group were selected for a 14-wk experiment in trial 1. Sixteen birds from the sham g... | ['Animals', 'Bone and Bones', 'Calcium', 'Chickens', 'Cholesterol', 'Dihydrotestosterone', 'Dose-Response Relationship, Drug', 'Drug Implants', 'Male', 'Nandrolone', 'Orchiectomy', 'Phosphorus', 'Random Allocation', 'Tensile Strength', 'Testosterone', 'Tibia', 'Weight Gain'] | 17,032,832 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['G07.690.773.875', 'G07... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modification of the discharge of lateral geniculate neurons during visual learning. | Visually conditioned heart rate change in the pigeon has been developed as a vertebrate model system for cellular analysis of associative learning. Previous studies have characterized the behavior, largely delineated the neural circuitry mediating the conditioning, and estimated the central processing time for the cond... | ['Analysis of Variance', 'Animals', 'Association Learning', 'Columbidae', 'Evoked Potentials, Visual', 'Female', 'Geniculate Bodies', 'Heart Rate', 'Learning', 'Light', 'Male', 'Neurons', 'Vision, Ocular'] | 3,958,787 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['F02.463.425.069.296'], ['B01.050.150.900.248.165.150'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['A08.186.211.200.317.826.701.444'], ['E01.370.600.875.500', 'G09.330.380.500'], ['F02.463.425', 'F02.784.629.529'], ['G01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structure of water in the vicinity of amphoteric polymers as revealed by Raman spectroscopy. | The structure and hydrogen bonding of water in an aqueous solution of amphoteric copolymers (poly(MA-r-DMAPMA), 3x10(3)<M(w)<10(4)) composed of various ratios of methacrylic acid (MA) and N-[3-(dimethylamino)propyl]methacrylamide (DMAPMA) were analyzed using the band shapes of the OH stretching in the polarized Raman s... | ['Electrochemistry', 'Hydrogen Bonding', 'Polymers', 'Spectrum Analysis, Raman', 'Water'] | 17,543,983 | [['H01.181.529.307'], ['G02.282'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.196.822.860', 'E05.196.867.890'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
High-fat diet triggers obesity-related early infiltration of macrophages into adipose tissue and transient reduction of blood monocyte count. | Infiltration of adipose tissue macrophages (ATMs) is a typical feature of obesity, and circulating immune cells may indicate immune cell accumulation. However, it remains unclear whether this is true in the early stages of obesity. This study aimed to define the role of blood monocytes in obesity and the relationship b... | ['Animals', 'Diet, High-Fat', 'Intra-Abdominal Fat', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Monocytes', 'Obesity'] | 31,778,913 | [['B01.050'], ['G07.203.650.240.267'], ['A10.165.114.830.500.500'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.118.637.555.652', 'A11.148.580',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of conserved histidines in the structure and stability of human papillomavirus type 16 E2 DNA-binding domain. | The E2 protein of papillomavirus is the key regulator of viral transcription and replication. Dimerization, which takes place via its conserved C-terminal DNA-binding domain (DBD), is critical for these functions. The presence and conservation of two histidines (H290 and H320) at or near the dimer interface suggests th... | ['Amino Acid Substitution', 'Binding Sites', 'Conserved Sequence', 'DNA-Binding Proteins', 'Dimerization', 'Histidine', 'Human papillomavirus 16', 'Humans', 'Hydrogen-Ion Concentration', 'Oncogene Proteins, Viral', 'Protein Conformation', 'Protein Denaturation', 'Protein Folding'] | 17,260,970 | [['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.120'], ['G02.111.570.580'], ['D12.776.260'], ['G02.206', 'G03.230'], ['D12.125.072.329', 'D12.125.142.308'], ['B04.280.210.655.050.616', 'B04.613.204.655.050.616'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D12.776.624.664.520', 'D12.776.964.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prenatal lead exposure enhances methamphetamine sensitization in rats. | Adult female rats were exposed to lead-free sodium acetate via gavage [0 mg (vehicle control)] or to 16 mg lead as lead acetate for 30 days prior to breeding. Following confirmation of breeding, the female animals continued to be exposed to their respective doses throughout gestation and lactation. When weaned, 16 cont... | ['Amphetamine-Related Disorders', 'Animals', 'Body Weight', 'Central Nervous System Stimulants', 'Dose-Response Relationship, Drug', 'Female', 'Injections, Intraperitoneal', 'Injections, Intravenous', 'Lead', 'Lead Poisoning, Nervous System', 'Male', 'Methamphetamine', 'Motor Activity', 'Pregnancy', 'Prenatal Exposure ... | 19,433,104 | [['C25.775.225', 'F03.900.225'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D27.505.696.282', 'D27.505.954.427.220'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.267.530.490'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of pro- and antifibrotic genes in protocol biopsies from renal allografts with interstitial fibrosis and tubular atrophy. | AIM: Better understanding of early onset of interstitial fibrosis and tubular atrophy (IF/TA), as the morphological surrogate of renal allograft deterioration might improve outcome after renal transplantation.MATERIAL AND METHODS: We quantified mRNA expression of 3 profibrotic (transforming growth factor-beta (TGF-beta... | ['Adult', 'Atrophy', 'Biopsy', 'Female', 'Fibrosis', 'Gene Expression', 'Graft Survival', 'Humans', 'Kidney', 'Kidney Diseases', 'Kidney Transplantation', 'Kidney Tubules', 'Male', 'Middle Aged', 'Transplantation, Homologous'] | 18,538,116 | [['M01.060.116'], ['C23.300.070'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C23.550.355'], ['G05.297'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419', 'C13.351.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Can Preoperative Sex-Related Differences in Hemostatic Parameters Predict Bleeding in Orthognathic Surgery? | PURPOSE: Bleeding volume in orthognathic surgery (OS) varies considerably, although OS comprises standardized procedures and the patient population consists of young healthy individuals. The aim of this prospective cohort study was to investigate the influence of preoperative sex-related differences in hemostatic param... | ['Adult', 'Biomarkers', 'Blood Loss, Surgical', 'Denmark', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Hemostasis, Surgical', 'Humans', 'Male', 'Orthognathic Surgical Procedures', 'Sex Factors'] | 27,083,576 | [['M01.060.116'], ['D23.101'], ['C23.550.414.300', 'C23.550.505.300'], ['Z01.542.816.124'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E02.520.490', 'E04.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.545.562', 'E04.555.580.289',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Unexpected photolysis of the sunscreen octinoxate in the presence of the sunscreen avobenzone. | A major concern raised about photostability studies of sunscreen products is that the photodegradation of sunscreens does not readily translate into changes in product performance. This study examines the correlation between photochemical degradation of sunscreen agents and changes in protection provided by sunscreen f... | ['Chalcones', 'Cinnamates', 'Electron Spin Resonance Spectroscopy', 'Molecular Structure', 'Photochemistry', 'Photolysis', 'Propiophenones', 'Sunscreening Agents', 'Ultraviolet Rays'] | 15,560,736 | [['D02.522.818.222', 'D03.383.663.283.266.450.221', 'D03.633.100.150.266.450.221'], ['D02.241.223.200'], ['E05.196.867.519.274'], ['G02.111.570', 'G02.466'], ['H01.181.529.711'], ['G02.740.685'], ['D02.522.818'], ['D27.505.696.706.776.800', 'D27.505.954.444.695', 'D27.720.269.800', 'D27.720.799.763.764'], ['G01.358.500... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Pre-neuronal morphological processing of object location by individual whiskers. | In the vibrissal system, touch information is conveyed by a receptorless whisker hair to follicle mechanoreceptors, which then provide input to the brain. We examined whether any processing, that is, meaningful transformation, occurs in the whisker itself. Using high-speed videography and tracking the movements of whis... | ['Afferent Pathways', 'Analysis of Variance', 'Anesthetics', 'Animals', 'Biomechanical Phenomena', 'Brain Mapping', 'Hair Follicle', 'Male', 'Mechanoreceptors', 'Movement', 'Physical Stimulation', 'Rats', 'Rats, Wistar', 'Reproducibility of Results', 'Time Factors', 'Vibrissae', 'Video Recording', 'Wakefulness'] | 23,563,582 | [['A08.612.220'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['A08.67... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Collagenase in synovial fluid. | Free collagenase activity was demonstrated in all 13 normal, 5 osteoarthrotic and 54 rheumatoid synovial fluids studied. Osteoarthrotic, normal, and rheumatoid fluids showed a free collagenase content increasing in that order. However, the total activities after trypsin activation did not differ significantly. The conc... | ['Arthritis, Rheumatoid', 'Humans', 'Microbial Collagenase', 'Osteoarthritis', 'Synovial Fluid', 'Trypsin', 'alpha 1-Antitrypsin', 'alpha-Macroglobulins'] | 79,218 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480.205.500', 'D08.811.277.656.675.374.205.500'], ['C05.550.114.606', 'C05.799.613'], ['A02.835.583.443.800.800', 'A12.207.270.847'], ['D08.811.277.656.300.760.895', 'D08.811.277... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of breaking up of the anterior border membrane of the vitreous body on the localization of anterior-chamber intraocular lenses]. | Cataract extraction with implantation of an anterior chamber lens was performed in 83 patients (118 eyes). In 3 patients occurred an intraoperative breaking up of the anterior limiting vitreous membrane. It had no influence on the early or late localization of the implanted lens. In the postoperative course one could o... | ['Adult', 'Aged', 'Anterior Chamber', 'Aphakia, Postcataract', 'Female', 'Humans', 'Intraoperative Complications', 'Lenses, Intraocular', 'Male', 'Middle Aged', 'Reoperation', 'Rupture', 'Vitreous Body'] | 1,821,012 | [['M01.060.116'], ['M01.060.116.100'], ['A09.371.060.067'], ['C11.510.103.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505'], ['E07.632.500.460', 'E07.695.460'], ['M01.060.116.630'], ['E04.690'], ['C26.761'], ['A09.371.714.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The amygdala central nucleus is required for acute stress-induced bladder hyperalgesia in a rat visceral pain model. | Chronic stress has been implicated in the pathogenesis of chronic visceral pain conditions, such as interstitial cystitis (IC), and bouts of acute stress exacerbate clinical urological pain. Studies using animal models have shown that exposure to chronic footshock stress augments reflex responses to urinary bladder dis... | ['Animals', 'Central Amygdaloid Nucleus', 'Disease Models, Animal', 'Electroshock', 'Female', 'Hyperalgesia', 'Nociception', 'Rats', 'Rats, Sprague-Dawley', 'Stress, Psychological', 'Urinary Bladder', 'Visceral Pain'] | 25,698,616 | [['B01.050'], ['A08.186.211.180.090.750', 'A08.186.211.200.885.287.249.152.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.723.402.403', 'F04.669.224'], ['C10.597.751.791.400', 'C23.888.592.763.770.400'], ['F02.463.593.504.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of 99mTc-sestamibi-18F-fluorodeoxyglucose dual isotope simultaneous acquisition and rest-stress 99mTc-sestamibi single photon emission computed tomography for the assessment of myocardial viability. | Dual isotope simultaneous acquisition single photon emission computed tomography (DISA SPECT) offers the advantage of obtaining information on myocardial perfusion using Tc-sestamibi ( Tc-MIBI) and metabolism using F-fluorodeoxyglucose ( F-FDG) in a single study. The prerequisite is that the Tc-MIBI images are not degr... | ['Adult', 'Aged', 'Angioplasty, Balloon, Coronary', 'Coronary Artery Bypass', 'Coronary Disease', 'Energy Metabolism', 'Exercise Test', 'Female', 'Fluorodeoxyglucose F18', 'Heart', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardium', 'Radiopharmaceuticals', 'Technetium Tc 99m Sestamibi', 'Tomography,... | 12,612,465 | [['M01.060.116'], ['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.28... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Detergent-like action of the antibiotic peptide surfactin on lipid membranes. | Surfactin is a bacterial lipopeptide with powerful surfactant-like properties. High-sensitivity isothermal titration calorimetry was used to study the self association and membrane partitioning of surfactin. The critical micellar concentration (CMC), was 7.5 microM, the heat of micellization was endothermic with DeltaH... | ['Bacterial Proteins', 'Calorimetry', 'Detergents', 'Lipopeptides', 'Liposomes', 'Micelles', 'Peptides, Cyclic', 'Phosphatidylcholines', 'Solubility', 'Temperature', 'Thermodynamics'] | 11,509,367 | [['D12.776.097'], ['E05.196.131'], ['D27.720.877.265', 'J01.516.381'], ['D10.477', 'D12.644.365'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D05.374', 'D26.255.560'], ['D04.345.566', 'D12.644.641'], ['D10.570.755.375.760.400.800'], ['G02.805'], ['G01.906.595', 'G16.500.275.063.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Sebaceous lymphadenoma of the lip: report of a case of minor salivary gland origin. | A case of sebaceous lymphadenoma occurring in the lip of a 73-year-old female is described. The patient had noticed a painless mass in the region of her upper lip for a year. The surgically removed tumor, measuring about 10 mm in diameter, was located just beneath the lip mucosa, expanding into the submucosal and muscl... | ['Aged', 'CD4-Positive T-Lymphocytes', 'Epithelial Cells', 'Female', 'Follow-Up Studies', 'Humans', 'Lip Neoplasms', 'Lymphocytes', 'Lymphoma', 'Salivary Gland Neoplasms', 'Salivary Glands, Minor', 'Sebaceous Gland Neoplasms', 'T-Lymphocytes'] | 12,076,329 | [['M01.060.116.100'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.436'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.591.550', 'C07.465.409.640', 'C0... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Family structure and income inequality in families with children, 1976 to 2000. | Using 24 years of data from the March supplements to the Current Population Survey and detailed categories of family structure, including cohabiting unions, I assess the contribution of changes in family structure to the dramatic rise in family income inequality. Between 1976 and 2000, family structure shifts explain 4... | ['Adolescent', 'Adult', 'African Americans', 'Child', 'Data Collection', 'European Continental Ancestry Group', 'Family Characteristics', 'Female', 'Hispanic Americans', 'Humans', 'Longitudinal Studies', 'Male', 'Marital Status', 'Middle Aged', 'Poverty', 'Social Class', 'United States'] | 17,051,821 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.406'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['M01.686.508.400'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['M01.686.754.441'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Aspects of the development and sex specific prevalence of psychogenic diseases in children and adults in relation to genetic and environmental factors]. | We investigated a sample of one hundred twins as to their neurotic disturbances in childhood and adulthood. The hereditary factor was of greater effect with the continuing neuroses of childhood than with the weakening neuroses in childhood. But a certain effect of the hereditary factor could not be denied with neuroses... | ['Adolescent', 'Adult', 'Child', 'Diseases in Twins', 'Follow-Up Studies', 'Humans', 'Neurotic Disorders', 'Personality Development', 'Psychoanalytic Therapy', 'Psychophysiologic Disorders', 'Risk Factors', 'Sex Factors', 'Social Environment'] | 1,853,651 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C23.550.291.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.550', 'F03.650'], ['F01.752.747'], ['F04.754.709'], ['C23.888.592.700'], ['E05.318.740.600.800.72... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Total flavonoids of Scutellaria barbata inhibit invasion of hepatocarcinoma via MMP/TIMP in vitro. | Metastasis is the major cause of cancer-related deaths. Targeting the process of metastasis has been proposed as a strategy to fight cancer. Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is used for treatment of many diseases, including cancer. This study aimed to determine the anti-metastat... | ['Antineoplastic Agents, Phytogenic', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Flavonoids', 'Gene Expression', 'Gene Expression Regulation', 'Humans', 'Inhibitory Concentration 50', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 9', 'Plant Extracts', 'Scutellaria... | 23,344,202 | [['D27.505.954.248.179'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G05.297'], ['G05.308'], ['B01.050.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Semi-automated 96-well liquid-liquid extraction for quantitation of drugs in biological fluids. | A semi-automated liquid-liquid extraction (LLE) technique for biological fluid sample preparation was introduced for the quantitation of four drugs in rat plasma. All liquid transferring during the sample preparation was automated using a Tomtec Quadra 96 Model 320 liquid handling robot, which processed up to 96 sample... | ['Algorithms', 'Animals', 'Autoanalysis', 'Chromatography, High Pressure Liquid', 'Indicators and Reagents', 'Mass Spectrometry', 'Microcomputers', 'Pharmaceutical Preparations', 'Rats', 'Reproducibility of Results', 'Solvents'] | 10,727,132 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E05.059'], ['E05.196.181.400.300'], ['D27.720.470.410'], ['E05.196.566'], ['L01.224.230.260.550'], ['D26'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['D27.720.844']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Safeguarding good scientific practice: new institutional approaches in Germany. | After summarising three recent case histories of alleged scientific misconduct in Germany, the efforts of the Deutsche Forschungsgemeinschaft (German Research Council) and the Hochschulrektorenkonferenz (German Rectors' Conference) to promote academic and procedural safeguards in favour of professional self-regulation ... | ['Ethics', 'Ethics Committees', 'Germany', 'Scientific Misconduct', 'Universities'] | 11,273,436 | [['K01.752.566.479', 'N05.350'], ['K01.752.566.479.147', 'N04.452.758.788.300', 'N05.350.268', 'N05.700.685.300'], ['Z01.542.315'], ['K01.752.566.479.915.500', 'N05.350.979.500'], ['I02.783.830', 'J03.832.830']] | ['Humanities [K]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Central skeletal sarcoidosis mimicking metastatic disease. | Sarcoidosis is a systemic disease that histologically typically shows non-caseating granulomas. The most common radiologic finding is hilar and mediastinal adenopathy. Patients with widely disseminated disease may show involvement of the peripheral appendicular skeleton in 1-13% of such cases. A primary skeletal presen... | ['Biopsy', 'Bone Diseases', 'Bone Neoplasms', 'Diagnosis, Differential', 'Fluorodeoxyglucose F18', 'Humans', 'Male', 'Middle Aged', 'Radiopharmaceuticals', 'Sarcoidosis', 'Tomography, Emission-Computed', 'Tomography, X-Ray Computed'] | 18,401,580 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C05.116'], ['C04.588.149', 'C05.116.231'], ['E01.171'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D27.505.259.843', 'D27.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessing risk factors for obesity between childhood and adolescence: I. Birth weight, childhood adiposity, parental obesity, insulin, and leptin. | OBJECTIVE: To assess the effects of body weight, body composition, parental obesity, and metabolic variables on the development of obesity in a large cohort of 5-year-old Native American children with a high propensity for obesity.METHODS: During the summer months of 1992 to 1995 and again 5 years later, 138 (65 boys a... | ['Adipose Tissue', 'Adolescent', 'Anthropometry', 'Birth Weight', 'Blood Glucose', 'Body Composition', 'Child', 'Cross-Sectional Studies', 'Female', 'Humans', 'Indians, North American', 'Insulin', 'Leptin', 'Linear Models', 'Longitudinal Studies', 'Male', 'Obesity', 'Risk Assessment'] | 12,165,582 | [['A10.165.114'], ['M01.060.057'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['D09.947.875.359.448.500'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['M01.060.406'], ['E0... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Analysis of the mineral element contents of axenic and natural Dunaliella salina]. | The contents of eleven mineral elements, including Mg, Fe, K, Ca, Na, Mn, Zn, Cu, Ni, Cd and Cr contents of axenic and natural Dunaliella salina and their culture supernatants in the different period of exponential phase were determined with flame atomic absorption spectrophotometer(AAS). The results show as follows: (... | ['Chlorophyta', 'Minerals', 'Spectrophotometry, Atomic'] | 20,828,008 | [['B01.650.940.150'], ['D01.578'], ['E05.196.712.726.551', 'E05.196.867.826.551']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognostic performance of three lymph node staging schemes for patients with Siewert type II adenocarcinoma of esophagogastric junction. | The prognostic performance of different lymph node staging schemes for adenocarcinoma of esophagogastric junction (AEG) remains controversial. The objective of the present study was to compare the prognostic efficacy of the number of lymph node metastases (LNMs), the positive lymph node ratio (LNR) and the log odds of ... | ['Adenocarcinoma', 'Aged', 'Esophageal Neoplasms', 'Esophagogastric Junction', 'Female', 'Humans', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Staging'] | 28,860,457 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['A03.556.875.500.414', 'A03.556.875.875.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.550.727.65... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Fluorometric determination of hydrochlorothiazide in body fluids by direct measurement of thin-layer chromatographic plates (author's transl)]. | Two fluorometric methods for analysis of hydrochlorothiazide (HCT) are described utilizing direct measurement of thin-layer plates. The first method employs a modification of the Bratton-Marshall reaction and is therefore applicable to all aromatic primary amines. Following diazotation and azocoupling of the HCT hydrol... | ['Chromatography, Thin Layer', 'Humans', 'Hydrochlorothiazide', 'Methods', 'Saliva', 'Spectrometry, Fluorescence'] | 914,951 | [['E05.196.181.400.537'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.590.700.135.261.476', 'D02.886.655.500.261.476', 'D03.633.100.174.261.476'], ['E05.581'], ['A12.200.666'], ['E05.196.712.516.600.676', 'E05.196.867.726']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coagulopathy induced by continuous infusion of high doses of human lymphoblastoid interferon. | Seven patients with myeloblastic leukemia were treated for 10 days with high-dose (15 or 30 million units/m2/day), human lymphoblastoid interferon (Wellferon) by continuous iv infusion. All patients developed prolonged activated partial thromboplastin time, and four developed prolonged prothrombin time. Factor assays d... | ['Adolescent', 'Adult', 'Blood Coagulation Disorders', 'Blood Coagulation Factors', 'Blood Coagulation Tests', 'Child', 'Child, Preschool', 'Drug Evaluation', 'Humans', 'Infant', 'Interferon Type I', 'Leukemia, Myeloid, Acute', 'Retrospective Studies'] | 3,856,479 | [['M01.060.057'], ['M01.060.116'], ['C15.378.100'], ['D12.776.124.125', 'D23.119'], ['E01.370.225.625.115', 'E05.200.625.115'], ['M01.060.406'], ['M01.060.406.448'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', '... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of Helicobacter pylori infection in aberrant DNA methylation along multistep gastric carcinogenesis. | CpG island hypermethylation is frequently found during gastric carcinogenesis. We investigated methylation profiles of p16, LOX, HAND1, THBD, p41ARC, and APC along multistep gastric carcinogenesis and determined their association with Helicobacter pylori infection. Methylation levels in these six genes were evaluated i... | ['Adult', 'Aged', 'Basic Helix-Loop-Helix Transcription Factors', 'DNA Methylation', 'Female', 'Gastric Mucosa', 'Gastritis', 'Genes, APC', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Metaplasia', 'Middle Aged', 'Precancerous Conditions', 'Stomach Neoplasms', 'Thrombomodulin'] | 20,345,486 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.260.103', 'D12.776.930.125'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C06.405.205.697', 'C06.405.748.398'], ['G05.360.340.024.340.375.249.050', 'G05.360.340.024.340.415.400.050'], ['C01.150.252.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Home blood pressure monitoring alone vs. combined clinic and ambulatory measurements in following treatment-induced changes in blood pressure and organ damage. | BACKGROUND: Out-of-office blood pressure (BP) measurement using home BP (HBP) or ambulatory BP (ABP) monitoring is often necessary for the accurate evaluation of hypertension. These methods have several similarities but also have major differences. Therefore, they are regarded as complementary, and there is uncertainty... | ['Adult', 'Blood Pressure Monitoring, Ambulatory', 'Humans', 'Hypertension', 'Middle Aged'] | 24,190,902 | [['M01.060.116'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primarily infected cephalhematoma and osteomyelitis in a newborn. | Cephalhematomas are subperiosteal blood collections occurring in newborns secondary to trauma at birth. They develop within a few days and are subsequently resorbed. Infection of a cephalhematoma is unusual and caused most often by colonization of the hematoma during bacteremia or by direct inoculation secondary to tra... | ['Birth Injuries', 'Hematoma', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Osteomyelitis', 'Parietal Bone', 'Tomography, X-Ray Computed'] | 9,892,568 | [['C16.614.131', 'C26.141'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['C01.160.495', 'C05.116.165.495'], ['A02.835.232.781.651'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alcohol-mediated error-prone PCR. | The effect of urea, isopropanol, propan-1-ol, and butan-1-ol on PCR using three different DNA polymerases was investigated. In the presence of these agents, polymerases were active as expected up to a critical concentration where they became progressively inhibited. Critical concentrations of alcohols generally increas... | ['1-Propanol', '2-Propanol', 'Base Sequence', 'Butanols', 'DNA Primers', 'Polymerase Chain Reaction', 'Urea'] | 15,585,138 | [['D02.033.755.600'], ['D02.033.755.615'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.033.415.110', 'D10.289.110'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.393.620.500'], ['D02.065.950']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Responses to neither exogenous nor endogenous endothelin-1 are altered in patients with hypercholesterolemia. | There is some controversy regarding whether vascular responses to endothelin are altered in hypercholesterolemia. Studies performed to date have been compromised by the use of endothelin antagonists at inappropriate concentrations. In the current study, we examine the role of endothelin-1 in hypercholesterolemic patien... | ['Blood Pressure', 'Endothelin-1', 'Female', 'Humans', 'Hypercholesterolemia', 'Male', 'Middle Aged', 'Receptor, Endothelin A', 'Receptor, Endothelin B', 'Regional Blood Flow'] | 16,177,446 | [['E01.370.600.875.249', 'G09.330.380.076'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['M01.060.116.630'], ['D12.776.543.750.695.220.100', 'D12.776.543.750.750.320.100'], ['D12.776.543.750.695.220.200', 'D12.776.543.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Drosophila transcription factor tramtrack (TTK) interacts with Trithorax-like (GAGA) and represses GAGA-mediated activation. | In this study, we report the interaction of the Drosophila transcription factors Trithorax-like (GAGA) and tramtrack (TTK). This interaction is documented both in vitro, through GST pull-down assays, as well as in vivo, in yeast and Schneider S2 cells. GAGA and TTK share in common the presence of an N-terminal POZ/BTB ... | ['Animals', 'Bacterial Proteins', 'Cell Line', 'DNA-Binding Proteins', 'Dimerization', 'Drosophila', 'Drosophila Proteins', 'Gene Expression Regulation', 'Homeodomain Proteins', 'Models, Molecular', 'Promoter Regions, Genetic', 'Protein Structure, Tertiary', 'Repressor Proteins', 'Transcription Factors', 'Transcription... | 12,384,587 | [['B01.050'], ['D12.776.097'], ['A11.251.210'], ['D12.776.260'], ['G02.206', 'G03.230'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['G05.308'], ['D12.776.260.400'], ['E05.599.595'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.570.820.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Follicular dendritic cell-B cell interactions in virus disease. Common localization but different cell damage caused by antibody immobilized virus? | Follicular dendritic cells (FDC) are involved in the trapping and retention of antigen-antibody complexes in lymphoid follicles. This FDC immobilized antigen is thought to be involved in the generation of memory B-lymphocytes. Follicular trapping of both Aleutian disease virus and HIV particles has been demonstrated. H... | ['Aleutian Mink Disease Virus', 'Antibodies, Viral', 'B-Lymphocytes', 'Dendritic Cells', 'HIV Infections', 'Immunologic Memory'] | 1,309,642 | [['B04.280.580.650.040.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissolution enhancement by bio-inspired mesocrystals: the study of racemic (R,S)-(+/-)-sodium ibuprofen dihydrate. | PURPOSE: The aim of this paper is to enhance the dissolution rate of racemic (R,S)-(+/-)-sodium ibuprofen dihydrate via a bio-inspired method of growing mesocrystals.MATERIALS AND METHODS: Mesocrystals of racemic (R,S)-(+/-)-sodium ibuprofen dihydrate were successfully prepared from a supersaturated aqueous solution of... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Calorimetry, Differential Scanning', 'Cetrimonium', 'Cetrimonium Compounds', 'Electric Conductivity', 'Ibuprofen', 'Indicators and Reagents', 'Light', 'Microscopy, Electron, Scanning', 'Particle Size', 'Reproducibility of Results', 'Scattering, Radiation', 'Sodium Dodecyl Su... | 18,302,008 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.196.131.310', 'E05.196.370.310'], ['D02.092.877.883.111.500', 'D02.675.276.190.500'], ['D02.092.877.883.111', 'D02.675.276.190'], ['G01.358.500.249.277'], ['D02.241.223.701.430'], ['D27.720.470.410'], ['G01.358.500.505.650', 'G01.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
T cell-mediated terminal maturation of dendritic cells: loss of adhesive and phagocytotic capacities. | Dendritic cells (DC) are a specific subset of APC characterized by the potent ability to activate immunologically naive T cells. We have observed previously that the murine epidermis-derived DC line XS52 undergoes a set of profound changes upon Ag-specific interaction with T cells, including IL-1 beta secretion acquire... | ['Animals', 'Cell Adhesion', 'Cell Communication', 'Cell Differentiation', 'Cell Line', 'Dendritic Cells', 'Epidermis', 'Epitopes', 'Interferon-gamma', 'Mice', 'Mice, Inbred BALB C', 'Phagocytosis', 'T-Lymphocytes'] | 8,805,631 | [['B01.050'], ['G04.022'], ['G04.085'], ['G04.152'], ['A11.251.210'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['A10.272.497', 'A17.815.250'], ['D23.050.550'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coarse-Graining the Liquid-Liquid Interfaces with the MARTINI Force Field: How Is the Interfacial Tension Reproduced? | We report two-phase coarse-grained (CG) simulations of organic-water liquid-liquid interfaces with the MARTINI force field. We discuss the ability of the CG force field to predict quantitatively the interfacial tension of alkanes-water, benzene-water, chloroform-water, and alcohol-water systems. The performance of the ... | ['Alcohols', 'Alkanes', 'Benzene', 'Chloroform', 'Molecular Dynamics Simulation', 'Organic Chemicals', 'Static Electricity', 'Temperature', 'Water'] | 26,574,463 | [['D02.033'], ['D02.455.326.146'], ['D02.455.426.559.389.023'], ['D02.455.526.439.224', 'D02.455.526.913.810'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D02'], ['G01.358.500.249.820'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. | The availability of antitumor cytotoxic T lymphocytes which can be generated from either peripheral blood lymphocytes after stimulation in vitro or tumor infiltrating lymphocytes (TIL) has made it possible to identify a number of melanoma antigens presented by major histocompatibility complex class I molecules. The pre... | ['Antigens, Neoplasm', 'Cell Line', 'Cloning, Molecular', 'DNA, Complementary', 'HLA-A Antigens', 'Humans', 'Lymphocytes, Tumor-Infiltrating', 'Melanoma', 'Tumor Cells, Cultured'] | 7,836,932 | [['D23.050.285'], ['A11.251.210'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.776.395.550.489.400', 'D12.776.543.550.439.400', 'D23.050.301.500.100.400', 'D23.050.301.500.450.370', 'D23.050.705.552.100.400', 'D23.050.705.552.450.370'], ['B01.050.150.900.649.313... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Staphylococcal and streptococcal infections of the skin. | Acute pyogenic infections of the skin, caused by hemolytic streptococci and S. aureus, account for the vast majority of bacterial infections of the skin seen in ambulatory practice. In preschool children the principal manifestation is pyoderma, which is usually caused by Group A Streptococcus. In this age group pyoderm... | ['Adolescent', 'Adult', 'Carbuncle', 'Cellulitis', 'Child', 'Erysipelas', 'Female', 'Folliculitis', 'Furunculosis', 'Humans', 'Impetigo', 'Male', 'Skin Diseases, Infectious', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Streptococcal Infections', 'Streptococcus pyogenes'] | 379,890 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Convex dynamics: unavoidable difficulties in bounding some greedy algorithms. | A greedy algorithm for scheduling and digital printing with inputs in a convex polytope, and vertices of this polytope as successive outputs, has recently been proven to be bounded for any convex polytope in any dimension. This boundedness property follows readily from the existence of some invariant region for a dynam... | ['Algorithms', 'Computer Simulation', 'Models, Statistical', 'Nonlinear Dynamics', 'Signal Processing, Computer-Assisted'] | 15,003,045 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.599.850', 'H01.548.675'], ['L01.224.800']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Altered glial fibrillary acidic protein content and its degradation in the hippocampus, cortex and cerebellum of rats exposed to constant light: reversal by melatonin. | Reactive astrocytosis is a well-known phenomenon that occurs rapidly after physical or metabolic injury to the brain. One of the important events during astrocyte differentiation is the increased expression of glial fibrillary acidic protein (GFAP), a member of the family of intermediate filament structural proteins. F... | ['Animals', 'Antioxidants', 'Brain', 'Cerebellum', 'Cerebral Cortex', 'Free Radicals', 'Glial Fibrillary Acidic Protein', 'Glutathione', 'Hippocampus', 'Lipid Peroxidation', 'Male', 'Melatonin', 'Photoperiod', 'Rats', 'Rats, Wistar', 'Reactive Oxygen Species'] | 12,220,326 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A08.186.211'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['D01.339', 'D02.389'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['D12.644.456.448'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G02.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical and Physiological Factors Influence Behavioral Responses of Cochliomyia macellaria (Diptera: Calliphoridae) to Synthetic Attractants. | Volatile chemicals from waste artificial larval media as well as from bovine blood inoculated with bacteria isolated from screwworm-infested wounds attract gravid females of Cochliomyia hominivorax Coquerel and Cochliomyia macellaria (F.). Chemicals identified from volatiles are dimethyl disulfide, dimethyl trisulfide,... | ['Age Factors', 'Animals', 'Chemotaxis', 'Diptera', 'Female', 'Male', 'Oviposition', 'Pheromones', 'Sex Factors'] | 28,535,247 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['B01.050.500.131.617.720.500.500.750'], ['G08.686.784.480'], ['D23.641'], ['N05.715.350.675', 'N06.850.490.875']] | ['Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Procedure volume of gastric cancer resections versus 5-year survival. | AIM: We used nationwide, population-based data to examine associations between hospital and surgeon volumes of gastric cancer resections and their patients' short-term and long-term survival likelihood.METHODS: The study uses 1997-1999 inpatient claims data from Taiwan's National Health Insurance linked to "cause of de... | ['Adult', 'Aged', 'Female', 'Gastrectomy', 'Hospitals', 'Humans', 'Male', 'Middle Aged', 'Stomach Neoplasms', 'Survival Rate', 'Taiwan', 'Time Factors'] | 17,890,043 | [['M01.060.116'], ['M01.060.116.100'], ['E04.210.419'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.975.550.900', 'N06.850.520.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.