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Impact of classical risk factors of type 2 diabetes among Asian Indian, Chinese and Japanese populations. | AIMS: This review investigated the population impact of major modifiable type 2 diabetes (T2D) risk factors, with special focus on native Asian Indians, to estimate population attributable risks (PARs) and compare them with estimates from Chinese and Japanese populations.METHODS: Information was obtained on risk factor... | ['Age Factors', 'Asia', 'Asian Continental Ancestry Group', 'Body Mass Index', 'Cohort Studies', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 2', 'Female', 'Fiji', 'Health Surveys', 'Humans', 'Hypercholesterolemia', 'Hypertension', 'Hypertriglyceridemia', 'Incidence', 'Male', 'Mauritius', 'Middle Aged', 'Obesity... | 26,381,573 | [['N05.715.350.075', 'N06.850.490.250'], ['Z01.252'], ['M01.686.508.200'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.... | ['Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Incorporating platelet-rich plasma into coaxial electrospun nanofibers for bone tissue engineering. | Platelet-rich plasma (PRP) is used in therapy for bone tissue repair because an abundance of osteogenesis-related growth factors can be released from the concentrated platelets. However, its clinical use is limited because growth factors, temporally released from PRP, are degraded rapidly. This study aimed to incorpora... | ['Animals', 'Bone Regeneration', 'Calcium Phosphates', 'Cell Culture Techniques', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Disease Models, Animal', 'Drug Compounding', 'Drug Liberation', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Male', 'Mesenchymal Stem Cell Transplantation', ... | 29,886,100 | [['B01.050'], ['G11.427.213.140', 'G16.762.150.150'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Case-control study of clinical features of influenza in hospitalized patients. | BACKGROUND: The symptoms of influenza infection in outpatients are well described. The Centers for Disease Control and Prevention (CDC) definition of an influenza-like illness (ILI) includes fever and cough or sore throat. Few data exist on the clinical presentation of influenza in hospitalized patients, which may be d... | ['Aged', 'Asthma', 'Case-Control Studies', 'Centers for Disease Control and Prevention, U.S.', 'Cough', 'Female', 'Fever', 'Hospitalization', 'Hospitals, Teaching', 'Hospitals, Urban', 'Humans', 'Influenza, Human', 'Male', 'Pharyngitis', 'Predictive Value of Tests', 'Sensitivity and Specificity', 'United States'] | 18,754,739 | [['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['C08.618.248', 'C23.888.852.293'], ['C23.888.119.344'], ['E02.760.400', 'N02... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Association of Diaphragmatic Surgery as Part of Cytoreductive Effort in Advanced Stage Ovarian Cancer. | BACKGROUND/AIM: Diaphragmatic surgery in advanced-stage ovarian cancer has been considered since long time to increase the rates of postoperative complications. However, improvement of surgical techniques and perioperative management of these patients has lead in the last decade to a safe association of such procedures... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Cytoreduction Surgical Procedures', 'Diaphragm', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Metastasis', 'Neoplasm Staging', 'Ovarian Neoplasms', 'Retrospective Studies', 'Treatment Outcome'] | 29,475,933 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['E04.166'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.612'], ['C04.697.650', 'C23.550.727.650'], ['E01.789.625'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metrizamide CT scanning in spinal nerve root cysts. | Two cases of lumbosacral root cysts of different etiology are reported. Their specific radiographic features are described using the combined technique of metrizamide myelography followed by computerized tomography of the spine. The terminology of intraspinal cysts is reviewed and their distinguishing features discusse... | ['Cysts', 'Female', 'Humans', 'Male', 'Metrizamide', 'Middle Aged', 'Nervous System Diseases', 'Spinal Nerve Roots', 'Tomography, X-Ray Computed'] | 3,607,616 | [['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.400.880.520', 'D02.455.426.559.389.127.375.880.520', 'D09.408.051.545'], ['M01.060.116.630'], ['C10'], ['A08.800.800.720.725'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.7... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The importance of tacit knowledge in practices of care. | BACKGROUND: The paper argues that a high quality personal relationship between professionals and clients is a necessary condition of professional knowledge. This epistemological claim is developed against the background of current methods of quality assessment that rely on objectively measurable 'indicators'.METHOD: A ... | ['Behavior', 'Caregivers', 'Clinical Competence', 'Delivery of Health Care', 'Empathy', 'Health Knowledge, Attitudes, Practice', 'Health Personnel', 'Humans', 'Intellectual Disability', 'Interpersonal Relations', 'Patients', 'Quality of Health Care', 'Speech Therapy'] | 20,586,882 | [['F01.145'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['N04.590.374', 'N05.300'], ['F01.752.355', 'F01.752.543.500.500'], ['F01.100.150.500', 'N05.300.150.410'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C2... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Role of the Institute of Rheumatology in formation and development of State controlling system of rheumatic diseases]. | The paper gives a brief account of the stages of formation and development of rheumatological care in the country, which are closely related to the researches and practical activities of the Institute of Rheumatology. | ['Academies and Institutes', 'Antirheumatic Agents', 'Humans', 'Research', 'Rheumatic Diseases', 'Rheumatology', 'Russia'] | 9,987,951 | [['N03.540.052'], ['D27.505.954.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644'], ['C05.799', 'C17.300.775'], ['H02.403.429.730'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
A genome phylogeny for mitochondria among alpha-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes. | Analyses of 55 individual and 31 concatenated protein data sets encoded in Reclinomonas americana and Marchantia polymorpha mitochondrial genomes revealed that current methods for constructing phylogenetic trees are insufficiently sensitive (or artifact-insensitive) to ascertain the sister of mitochondria among the cur... | ['Alphaproteobacteria', 'Archaea', 'Bacteria', 'Bacterial Proteins', 'Carrier Proteins', 'Evolution, Molecular', 'Genes, Archaeal', 'Genes, Bacterial', 'Genes, Fungal', 'Genome', 'Mitochondria', 'Mitochondrial Proteins', 'Models, Genetic', 'Phylogeny', 'Rhodospirillum rubrum', 'Saccharomyces cerevisiae', 'Saccharomyces... | 15,155,797 | [['B03.660.050'], ['B02'], ['B03'], ['D12.776.097'], ['D12.776.157'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.364.124', 'G05.360.340.358.024.124', 'G05.360.340.358.050.500'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.340.364.500', 'G05.360.340... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Permanent alopecia after busulfan chemotherapy. | Systemic chemotherapy is a well known cause of reversible hair loss. Busulfan chemotherapy, however, is responsible for a permanent alopecia that usually occurs in bone marrow transplant patients. We report two patients with permanent alopecia due to busulfan chemotherapy. Both patients had a diffuse alopecia character... | ['Adult', 'Alopecia', 'Antineoplastic Agents, Alkylating', 'Bone Marrow Transplantation', 'Busulfan', 'Female', 'Humans', 'Transplantation Conditioning'] | 15,888,171 | [['M01.060.116'], ['C17.800.329.937.122', 'C23.300.035'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D02.033.455.125.125', 'D02.455.326.146.100.050.500.100', 'D02.886.645.600.055.050.510.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antitoxin MqsA represses curli formation through the master biofilm regulator CsgD. | MqsA, the antitoxin of the MqsR/MqsA toxin/antitoxin (TA) system, is a global regulator that reduces expression of several stress response genes (e.g., mqsRA, cspD, and rpoS) by binding to the promoter palindromic motif [5'-AACCT (N)₃ AGGTT-3']. We identified a similar mqsRA-like palindrome [5'-AACCT TA AGGTT-3'] 78 bp... | ['Bacterial Proteins', 'Base Sequence', 'Biofilms', 'DNA-Binding Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Protein Binding', 'Sigma Factor', 'Trans-Activators', 'Transcription, Genetic'] | 24,212,724 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A20.593', 'G06.120'], ['D12.776.260'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['L01.453.245.667'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.679', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. | Cocaine exposure alters gene expression in the brain via methylation and acetylation of histones along with methylation of DNA. Recently, poly (ADP-ribose) polymerase-1 (PARP-1) catalyzed PARylation has been reported as an important regulator of cocaine-mediated gene expression. In this study, we report that the cellul... | ['Animals', 'Annexin A5', 'Apoptosis', 'Brain', 'Cattle', 'Cell Line, Tumor', 'Cocaine', 'Dopamine Plasma Membrane Transport Proteins', 'Dopamine Uptake Inhibitors', 'Dopaminergic Neurons', 'Enzyme Activation', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'MicroRNAs', 'Neur... | 28,828,398 | [['B01.050'], ['D12.776.157.125.050.100'], ['G04.146.954.035'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D12.776.157.530.450.625.124', 'D12.776.157.530.562.374.500.500', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pseudouridine and uridine in normal kidney and kidney cancer tissues. | The tissue concentrations of a modified nucleoside, pseudouridine, and a normal nucleoside, uridine, were measured with high-performance liquid chromatography. Human kidneys were obtained from five patients with renal cell carcinoma and divided into a noncancerous part and a cancerous part. The pseudouridine concentrat... | ['Carcinoma, Renal Cell', 'Chromatography, High Pressure Liquid', 'Humans', 'Kidney', 'Kidney Neoplasms', 'Pseudouridine', 'Tissue Distribution', 'Uridine'] | 4,060,365 | [['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.9... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sequential studies of lymphocytes, neutrophils and serum proteins during prednisone treatment. | Seven patients (6 with connective tissue diseases, 1 with bronchial asthma) have been studied before, during, and after prednisone therapy. Maximum dose was 15 mg daily, which was tapered off to zero within three months. All patients showed striking subjective improvement during therapy. The ESR reflected this improvem... | ['Adult', 'Aged', 'Asthma', 'Blood Proteins', 'Blood Sedimentation', 'Collagen Diseases', 'Female', 'Haptoglobins', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Lymphocyte Activation', 'Lymphocytes', 'Male', 'Middle Aged', 'Neutrophils', 'Orosomucoid', 'Prealbumin', 'Prednisone', 'Serum Albumi... | 1,082,710 | [['M01.060.116'], ['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D12.776.124'], ['E01.370.225.625.125', 'E05.200.625.125'], ['C17.300.200'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of carbon dioxide induction methods for the euthanasia of day-old cull broiler chicks. | This study was conducted to evaluate the efficacy of 5 different CO2 euthanasia induction techniques for day-old cull chicks in minimizing distress and inducing a rapid loss of sensibility and death. Each induction treatment was characterized for concentration change over time, maximum concentration, and time to reach ... | ['Animal Welfare', 'Animals', 'Carbon Dioxide', 'Chickens', 'Euthanasia, Animal', 'Female', 'Male', 'Random Allocation'] | 30,624,707 | [['I01.880.604.100'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E02.760.905.199.249.750', 'E05.335', 'N02.421.585.905.199.500.750'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Image-quality perception as a function of dose in digital radiography. | OBJECTIVE: The purpose of this article is to determine the degree to which the skin entrance dose could be lowered, by adjusting exposure parameters and filtration, and the subsequent effect on readers' confidence levels of digital radiographs.MATERIALS AND METHODS: The study was prospectively performed on a cadaver. D... | ['Aluminum', 'Bone and Bones', 'Cadaver', 'Copper', 'Filtration', 'Humans', 'Male', 'Prospective Studies', 'Radiation Dosage', 'Radiographic Image Enhancement', 'Radiometry', 'Skin'] | 22,109,295 | [['D01.268.557.050', 'D01.552.547.050'], ['A02.835.232', 'A10.165.265'], ['C23.550.260.224'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The relationship between maternal self-efficacy and parenting practices: implications for parent training. | The present study examined the relationship between maternal self-efficacy, dysfunctional discipline practices and child conduct problems. Specifically, three levels of self-efficacy, global, domain and task-specific self-efficacy, were assessed in mothers of 2- to 8-year-old children with conduct problems (clinic grou... | ['Adult', 'Child', 'Child Behavior Disorders', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Mother-Child Relations', 'Mothers', 'Parenting', 'Risk Factors', 'Self Efficacy', 'Social Control, Informal', 'Social Perception', 'Social Support', 'Socioeconomic Factors', 'Stress, Psychological'] | 15,658,967 | [['M01.060.116'], ['M01.060.406'], ['F03.625.141'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290.170'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['F01.829.263.370.310'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.6... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Atypical peritoneal tuberculosis. Use of laparoscopy in the diagnosis]. | The presence of peritoneal tuberculosis has to be clinically suspected in all patients with abdominal pain of unknown etiology, particularly when it is accompanied by fever, ascites, and abdominal distension. Access to the abdominal cavity using routine laparoscopy provides essential information on the diagnosis, from ... | ['Female', 'Humans', 'Laparoscopy', 'Middle Aged', 'Peritonitis, Tuberculous'] | 18,290,699 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['C01.150.252.410.040.552.846.308', 'C01.463.600.249', 'C06.844.640.249']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Improving Adherence to Cardiovascular Therapies: An Economic Evaluation of a Randomized Pragmatic Trial. | OBJECTIVE: Preplanned economic analysis of a pragmatic trial using electronic-medical-record-linked interactive voice recognition (IVR) reminders for enhancing adherence to cardiovascular medications (i.e., statins, angiotensin-converting enzyme inhibitors [ACEIs], and angiotensin receptor blockers [ARBs]).METHODS: Thr... | ['Aged', 'Angiotensin II Type 1 Receptor Blockers', 'Angiotensin-Converting Enzyme Inhibitors', 'Biomarkers', 'Cardiovascular Agents', 'Cardiovascular Diseases', 'Cost-Benefit Analysis', 'Drug Costs', 'Electronic Health Records', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Resources', 'Humans', 'Hydroxym... | 27,021,751 | [['M01.060.116.100'], ['D27.505.519.162.500'], ['D27.505.519.389.745.085'], ['D23.101'], ['D27.505.954.411'], ['C14'], ['N03.219.151.125'], ['N03.219.151.400.350', 'N05.300.375.300'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['F01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Phenomena and Processes... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Catheter-directed foam sclerotherapy of incompetent saphenous reflux: early results]. | OBJECTIVE: To describe observation of availability of catheter-directed foam sclerotherapy for the great saphenous vein varicosis.METHODS: A selective series of 30 patients of vein varicosis were treated with foam sclerotherapy using a standard technique for foam delivery from April 2008 to August 2008. Patients were t... | ['Adult', 'Aged', 'Aged, 80 and over', 'Catheterization, Peripheral', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Saphenous Vein', 'Sclerosing Solutions', 'Sclerotherapy', 'Treatment Outcome', 'Varicose Veins'] | 20,193,405 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.015.908.819'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Managements for lateral sinus thrombosis: does it need the ligation of internal jugular vein or anticoagulants? | The purposes of this study were to review the clinical characteristics and treatment outcomes of patients with lateral sinus thrombosis (LST) and to discuss the need of internal jugular vein (IJV) ligation or anticoagulants. We retrospectively reviewed the charts of five patients (1 male and 4 female) with LST. The chi... | ['Adult', 'Aged', 'Anticoagulants', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Jugular Veins', 'Lateral Sinus Thrombosis', 'Ligation', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Phlebography', 'Risk Assessment', 'Sensitivity and Specificity', 'Severity of Illness Index', 'Tomography, X-Ray Computed',... | 18,535,833 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.502.119'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.908.498'], ['C10.228.140.300.525.425.500.562', 'C14.907.253.566.350.500.562', 'C14.907.35... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Clinical review of enteral feeding of extremely low birth weight infants]. | OBJECTIVE: To review the clinical data of enteral feeding of extremely low birth weight infants (ELBWI), and analyze the influencing factors.METHOD: From Jan. 2000 to Jan. 2010, data of 31 ELBWI from Peking Union Medical College Hospital were retrospectively collected. ELBWI were assigned to different groups according ... | ['Enteral Nutrition', 'Female', 'Gestational Age', 'Humans', 'Infant, Extremely Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Retrospective Studies'] | 21,575,375 | [['E02.421.360', 'E02.642.500.360'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460.600.500'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extranodal B-cell lymphoma of the uvea: a case report. | CASE REPORT: Ocular involvement by non-Hodgkin's lymphoma is a rare condition that can result from a primary intraocular lymphoma of the retina or an intraocular manifestation of systemic lymphoma. Uveal involvement is seldom the initial manifestation of extranodal lymphoma. We describe an 80-year-old patient with a bl... | ['Aged, 80 and over', 'Blindness', 'Eye Enucleation', 'Female', 'Humans', 'Lymphoma, B-Cell', 'Recurrence', 'Ultrasonography', 'Uveal Neoplasms', 'Uveitis'] | 16,391,629 | [['M01.060.116.100.080'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['E04.540.429'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480.150', 'C15.604.515.569.480.150', 'C20.683.515.761.480.150'], ['C23.550.291.937'], ['E01.370.350.850'], ['C04.588.364.978', 'C11.319.494', 'C11.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assay and characterization of a strong promoter element from B. subtilis. | A new strong promoter fragment isolated from Bacillus subtilis was identified and characterized. Using the heat stable beta-galactosidase as reporter, the promoter fragment exhibited high expression strength both in Escherichia coli and B. subtilis. The typical prokaryotic promoter conservation regions were found in th... | ['Bacillus subtilis', 'Bacterial Proteins', 'Escherichia coli', 'Promoter Regions, Genetic', 'Protein Engineering', 'Recombinant Proteins', 'Transfection', 'beta-Galactosidase'] | 17,210,127 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['E05.393.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hydrodynamic-induced enantiomeric enrichment of self-assemblies: role of the solid-liquid interface in chiral nucleation and seeding. | A simple hydrodynamic model has been developed to explain the experimentally observed chirality selection in stirred solutions of self-assembling achiral dyes. Selection depends on the stirring direction: the dichroic signal reverses its shape in clockwise or anti-clockwise rotations. Our model investigates the possibl... | ['Coloring Agents', 'Hydrodynamics', 'Models, Chemical', 'Stereoisomerism'] | 23,039,608 | [['D27.720.233'], ['G01.342'], ['E05.599.495'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A study of the effects of internal organ motion on dose escalation in conformal prostate treatments. | BACKGROUND AND PURPOSE: To assess the effect of internal organ motion on the dose distributions and biological indices for the target and non-target organs for three different conformal prostate treatment techniques.MATERIALS AND METHODS: We examined three types of treatment plans in 20 patients: (1) a six field plan, ... | ['Humans', 'Male', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Radiotherapy, Conformal', 'Rectum', 'Treatment Outcome', 'Urinary Bladder'] | 12,742,265 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.815.639'], ['E02.815.635.700', 'L01.313.500.750.100.710.600.550'], ['A03.556.124.526.767', 'A03.556.249.249.767'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Determination of amitriptyline and cocaine by GC and GC/MS in biological fluids. | A method of identification and quantitative determination of amitriptyline and cocaine at trace levels in biological fluids is described. After the extraction of both drugs from the biological material in an alkaline medium, and posterior purification and concentration of the extract, one proceeds to unequivocal identi... | ['Amitriptyline', 'Body Fluids', 'Chromatography, Gas', 'Cocaine', 'Gas Chromatography-Mass Spectrometry', 'Humans'] | 3,188,358 | [['D02.455.426.559.847.181.384.100', 'D04.615.181.384.100'], ['A12.207'], ['E05.196.181.349'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Construction of a double eyelid: an uncut strip of orbicularis removed through three mini-incisions. | BACKGROUND: In recent years, many mini-incisional techniques for double-eyelid plasty have been developed. However, the removal of pretarsal tissue has not been satisfactory because only small pockets of soft tissue just inferior to the skin have been removed to place the suture. The formed double eyelid may therefore ... | ['Adolescent', 'Adult', 'Blepharoplasty', 'Eyelids', 'Female', 'Humans', 'Male', 'Oculomotor Muscles', 'Suture Techniques', 'Young Adult'] | 23,296,762 | [['M01.060.057'], ['M01.060.116'], ['E04.540.104', 'E04.680.275.090'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.700'], ['E04.987.775'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A comparison of the relative efficacy of antiandrogens for the treatment of acne in hyperandrogenic women. | OBJECTIVES: To compare the relative effectiveness of two newer antiandrogens (flutamide and finasteride) with cyproterone acetate (CPA), at both low and high doses in the treatment of moderate to severe acne in hyperandrogenic women.SUBJECTS AND DESIGN: Forty-eight hyperandrogenic women were prospectively randomized to... | ['Acne Vulgaris', 'Adult', 'Androgen Antagonists', 'Cyproterone Acetate', 'Drug Administration Schedule', 'Female', 'Finasteride', 'Flutamide', 'Humans', 'Hyperandrogenism', 'Prospective Studies', 'Statistics, Nonparametric'] | 12,153,602 | [['C17.800.030.150', 'C17.800.794.111'], ['M01.060.116'], ['D06.347.065', 'D27.505.696.399.450.065'], ['D04.210.500.745.432.219.150', 'D04.210.500.883.419.150'], ['E02.319.283'], ['D04.210.500.054.079.500', 'D04.210.500.925.100.250'], ['D02.065.199.420', 'D02.092.146.113.420'], ['B01.050.150.900.649.313.988.400.112.400... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bacillus pumilus polysaccharide cross-reactive with meningococcal group A polysaccharide. | A polysaccharide, antigenically and structurally related to meningococcal group A polysaccharide, was isolated from Bacillus pumilus Sh-17. This enteric bacterium has been implicated as a source of natural meningococcal group A immunity (Myerowitz et al., 1973). The B. pumilus polysaccharide was composed of a homopolym... | ['Amino Acids', 'Bacillus', 'Chromatography, Gel', 'Cross Reactions', 'Lipopolysaccharides', 'Neisseria meningitidis', 'Periodic Acid', 'Polysaccharides, Bacterial', 'Species Specificity'] | 184,043 | [['D12.125'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['E05.196.181.400.250'], ['G12.122.281'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B03.440.400.425.550.550.641', 'B03.660.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The oestrogenic Fusarium toxin (zearalenone) in hay as a cause of early abortions in the cow. | In this study, the occurrence of a series of early abortions in a herd of cattle kept at an experimental station in North Savo has been described, the cause of which has evidently been hay feed in which the toxin zearalenone had formed. Several early abortions occurred in this particular herd 30-90 days after artificia... | ['Abortion, Veterinary', 'Animal Feed', 'Animals', 'Cattle', 'Cattle Diseases', 'Female', 'Food Contamination', 'Poaceae', 'Pregnancy', 'Resorcinols', 'Zearalenone'] | 6,240,023 | [['C13.703.039.422', 'C22.021'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.650.940.800.575.912.250.822'], ['G08.686.784.769'], ['D02.455.426.559.389.657.852'], ['D02.455.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Disease-modifying factors in hereditary angioedema: an RNA expression-based screening. | BACKGROUND: Hereditary Angioedema due to C1-Inhibitor deficiency (HAE types I and II) is a monogenic disease characterized by sudden, self-limited episodes of cutaneous and mucosal swelling due to local deregulation of vascular permeability. Despite its monogenic pattern of inheritance, HAE exhibits great clinical vari... | ['Complement C1 Inhibitor Protein', 'Family', 'Female', 'Gene Expression Regulation', 'Genetic Association Studies', 'Hereditary Angioedema Types I and II', 'Humans', 'Leukocytes, Mononuclear', 'Male', 'Middle Aged', 'Mutation', 'Oligonucleotide Array Sequence Analysis', 'Pedigree', 'RNA', 'Reverse Transcriptase Polyme... | 23,688,356 | [['D12.644.861.140.500', 'D12.776.124.486.274.920.250.500', 'D12.776.395.320', 'D12.776.872.140.500'], ['F01.829.263', 'I01.880.853.150'], ['G05.308'], ['E05.393.385'], ['C14.907.079.500.750', 'C17.800.862.945.066.500.750', 'C20.543.480.904.066.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.5... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly. | Adeno-associated virus (AAV) is gaining momentum as a gene therapy vector for human applications. However, there remain impediments to the development of this virus as a vector. One of these is the incomplete understanding of the biology of the virus, including nuclear targeting of the incoming virion during initial in... | ['Amino Acid Motifs', 'Capsid', 'Capsid Proteins', 'Dependovirus', 'HeLa Cells', 'Humans', 'Virus Assembly'] | 16,699,000 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['A21.249.500.250'], ['D12.776.964.970.600.550'], ['B04.280.580.650.170'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.920.925.950']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conformational States of Exchange Protein Directly Activated by cAMP (EPAC1) Revealed by Ensemble Modeling and Integrative Structural Biology. | Exchange proteins directly activated by cAMP (EPAC1 and EPAC2) are important allosteric regulators of cAMP-mediated signal transduction pathways. To understand the molecular mechanism of EPAC activation, we performed detailed Small-Angle X-ray Scattering (SAXS) analysis of EPAC1 in its apo (inactive), cAMP-bound, and e... | ['Cyclic AMP', 'Cyclic AMP-Dependent Protein Kinases', 'Guanine Nucleotide Exchange Factors', 'Humans', 'Protein Binding', 'Scattering, Small Angle', 'Signal Transduction', 'Structure-Activity Relationship', 'X-Ray Diffraction', 'rap GTP-Binding Proteins'] | 31,877,746 | [['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D12.644.360.325.300', 'D12.776.476.325.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.679', 'G03.808'], ['E05.196... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of peripheral benzodiazepine receptors in purified large mammal pancreatic islets. | In this work, we evaluated the biochemical properties of peripheral benzodiazepine receptors (PBRs) in the porcine endocrine pancreas and their role in insulin release. Binding of [3H]1-(2-chlorophenyl-N-methyl-1-methyl-propyl)-3-isoquinolinecarboxa mide ([3H]PK-11195), a specific ligand of PBRs, to islet membranes was... | ['Animals', 'Benzodiazepinones', 'Binding Sites', 'Cell Membrane', 'Convulsants', 'Glucose', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Isoquinolines', 'Receptors, GABA-A', 'Swine', 'Tritium'] | 8,630,084 | [['B01.050'], ['D03.633.100.079.080.070'], ['G02.111.570.120'], ['A11.284.149'], ['D27.505.696.282.224', 'D27.505.954.427.220.224'], ['D09.947.875.359.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', 'A06.300.414'], ['D03.633.100.531'], ['D12.776.157.530.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The quality of life of people with dementia and their family carers. | BACKGROUND: We aimed to identify factors associated with the quality of life (QoL) of 'persons with dementia' (PWDs) and their family carers.METHOD: Two-hundred and thirty dyads of PWDs and their family carers were included. The PWDs were assessed with the Neuropsychiatric Inventory (NPI-Q), two Activities of Daily Liv... | ['Activities of Daily Living', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Caregivers', 'Data Collection', 'Dementia', 'Depression', 'Educational Status', 'Female', 'Hobbies', 'Humans', 'Leisure Activities', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Occupations', 'Psychiatric Status Rating Scales', ... | 22,854,507 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['C10.228.140.380', 'F03.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells. | Ionizing radiation induces a diverse spectrum of DNA lesions, including strand breaks and oxidized bases. In mammalian cells, ionizing radiation-induced lesions are targets of non-homologous end joining, homologous recombination, and base excision repair. In vitro assays show a potential involvement of DNA polymerase l... | ['Animals', 'Camptothecin', 'Cell Line', 'Cell Survival', 'DNA Damage', 'DNA Polymerase beta', 'Etoposide', 'Genome', 'Genotype', 'Hydrogen Peroxide', 'Mice', 'Radiation Tolerance', 'Radiation, Ionizing'] | 18,088,185 | [['B01.050'], ['D03.132.151'], ['A11.251.210'], ['G04.346'], ['G05.200'], ['D08.811.913.696.445.308.300.112'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.960.675.250', 'D09.408.348.275'], ['G05.360.340'], ['G05.380'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treat-to-target in systemic lupus erythematosus: where are we today? | Multiple clinical trials performed over twenty years in the treatment of rheumatoid arthritis (RA) have clearly demonstrated that patients have better outcomes if their disease activity at each time-point for follow-up includes a pre-specified target. A European SLE expert panel met in Zurich on May 8, 2012 to discuss ... | ['Disease Progression', 'Humans', 'Lupus Erythematosus, Systemic', 'Patient Care Planning', 'Quality of Life', 'Treatment Outcome'] | 23,072,706 | [['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['N04.590.233.624'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Tangle evolution linked to differential 3- and 4-repeat tau isoform deposition: a double immunofluorolabeling study using two monoclonal antibodies. | Double immunofluorolabeling for 3-repeat (3R) and 4-repeat (4R) tau was performed with two monoclonal antibodies, RD3 and RD4, after an additional pretreatment with potassium permanganate and oxalic acid to eliminate nonspecific 3R tau cytoplasmic staining. This method involves hyperdilution of one of the primary monoc... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Antibodies, Monoclonal', 'Humans', 'Immunohistochemistry', 'Neurodegenerative Diseases', 'Neurofibrillary Tangles', 'Protein Isoforms', 'Staining and Labeling', 'Supranuclear Palsy, Progressive', 'tau Proteins'] | 22,116,524 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.50... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk factors and prevention of injuries to the cranial nerves in reconstructive surgery of the carotid arteries. | Reconstructive operations on aortic arch branches is the most effective approach to prevention of acute and chronic disorders of cerebral circulation. Iatrogenic injuries to the cranial nerves worsen the early end, particularly, the late postoperative period, decrease the quality of life and the social status of patien... | ['Carotid Artery Diseases', 'Cranial Nerve Injuries', 'Follow-Up Studies', 'Humans', 'Incidence', 'Intraoperative Complications', 'Monitoring, Intraoperative', 'Perioperative Care', 'Prospective Studies', 'Risk Factors', 'Russia', 'Time Factors', 'Vascular Surgical Procedures'] | 16,037,809 | [['C10.228.140.300.200', 'C14.907.253.123'], ['C10.292.200', 'C10.900.300.218', 'C26.915.300.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The inhibitory effect of TMK688, a novel anti-allergic drug having both 5-lipoxygenase inhibitory activity and anti-histamine activity, against bronchoconstriction, leukotriene production and inflammatory cell infiltration in sensitized guinea pigs. | BACKGROUND: TMK688 is being developed as an anti-allergic drug having both 5-lipoxygenase inhibitory activity and anti-histamine activity.METHOD: We compared the inhibition of the late asthmatic responses by TMK688 with that by other anti-allergic agents in actively sensitized guinea pigs, and examined the relationship... | ['Animals', 'Anti-Allergic Agents', 'Asthma', 'Bronchoconstriction', 'Chemotaxis, Leukocyte', 'Dose-Response Relationship, Drug', 'Eosinophils', 'Granulocytes', 'Guinea Pigs', 'Histamine Antagonists', 'Leukotrienes', 'Lipoxygenase Inhibitors', 'Lung', 'Male', 'Ovalbumin', 'Piperidines', 'Serine Proteinase Inhibitors'] | 9,117,875 | [['B01.050'], ['D27.505.954.016'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['G09.772.705.700.080'], ['G04.198.424.233'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['A11.118.637.415', 'A11.148.35... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Association between the polymorphism of HLA-DQA1 alleles and type 2 diabetes in Yi nationality of Yunnan]. | OBJECTIVE: To investigate the association between the polymorphism of HLA-DQA1 alleles and type 2 diabetes in Yi nationality of Yunnan.METHODS: Polymerase chain reaction with sequence-specific primers (PCR-SSP) genotyping method was conducted in 58 ethnic Yi patients with type 2 diabetes mellitus and 82 ethnically matc... | ['Adult', 'Aged', 'Aged, 80 and over', 'China', 'Diabetes Mellitus, Type 2', 'Female', 'Genetic Predisposition to Disease', 'HLA-DQ Antigens', 'HLA-DQ alpha-Chains', 'Humans', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Polymorphism, Genetic'] | 16,331,578 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.252.474.164'], ['C18.452.394.750.149', 'C19.246.300'], ['C23.550.291.687.500', 'G05.380.355'], ['D12.776.395.550.509.400.430', 'D12.776.543.550.440.400.430', 'D23.050.301.500.400.400.430', 'D23.050.301.500.450.400.430', 'D23.050.705.552.410.400.430',... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Findings on ambulatory electrocardiographic monitoring in subjects older than 80 years. | Twenty-four-hour electrocardiograms were recorded in 50 subjects (44 women, 6 men) older than 80 years without cardiovascular disease and with normal standard electrocardiographic responses. During waking and sleeping periods, the mean sinus rates were, respectively, 78 +/- 3 and 64 +/- 1 beats/min; heart rate ranged f... | ['Aged', 'Aging', 'Ambulatory Care', 'Arrhythmias, Cardiac', 'Atrioventricular Node', 'Circadian Rhythm', 'Electrocardiography', 'Female', 'Heart Rate', 'Heart Ventricles', 'Humans', 'Male', 'Monitoring, Physiologic', 'Tachycardia'] | 3,946,253 | [['M01.060.116.100'], ['G07.345.124'], ['E02.760.106', 'N02.421.585.106'], ['C14.280.067', 'C23.550.073'], ['A07.541.409.147'], ['G07.180.562.190'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A deficit survival analysis to assess the natural history of uveal melanoma. | A deficit survival analysis was conducted using a retrospective series of 230 patients with uveal melanoma. All underwent enucleation as primary treatment for their disease. Considering the three leading prognostic factors (epithelioid cells per high power field, tumor size, and tumor location), median age was plotted ... | ['Adult', 'Age Factors', 'Aged', 'Humans', 'Melanoma', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Time Factors', 'Uveal Neoplasms'] | 6,725,501 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Critical role of the transcription factor AP-1 for the constitutive and interferon-induced expression of IFI 16. | IFI 16 is a member of the HIN-200 family of transcriptional regulators that suppress cell growth, modulate the cell cycle and have been linked to cellular differentiation. We hypothesized that the activity of IFI 16 depends on its level of expression and therefore studied the transcriptional activity of the IFI 16 prom... | ['Base Sequence', 'Binding Sites', 'Cells, Cultured', 'DNA', 'Gene Expression Regulation', 'Genes, Reporter', 'HL-60 Cells', 'HeLa Cells', 'Humans', 'Interferon-gamma', 'Nuclear Proteins', 'Phosphoproteins', 'Promoter Regions, Genetic', 'Proteins', 'Recombinant Proteins', 'Tetradecanoylphorbol Acetate', 'Transcription ... | 12,682,910 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.251'], ['D13.444.308'], ['G05.308'], ['G05.360.340.024.340.435'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
APA hamster model for diabetic atherosclerosis. 2. Analysis of lipids and lipoproteins. | Syrian hamsters of the APA strain (APA hamsters) have recently been shown to have atheromatous lesions in the aortic arches under diabetic condition induced by a single injection of streptozotocin (SZ). In that model, fatty streaks, which are the initial lesions of atherogenesis, develop by 6 weeks after the injection ... | ['Aldehydes', 'Animals', 'Aortic Diseases', 'Arteriosclerosis', 'Cholesterol, LDL', 'Cricetinae', 'Diabetes Mellitus, Experimental', 'Diabetic Angiopathies', 'Disease Models, Animal', 'Enzyme-Linked Immunosorbent Assay', 'Foam Cells', 'Glycation End Products, Advanced', 'Immunohistochemistry', 'Lipid Peroxidation', 'Li... | 11,109,552 | [['D02.047'], ['B01.050'], ['C14.907.109'], ['C14.907.137.126'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['B01.050.150.900.649.313.992.635.075.250'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C14.907.320', 'C19.246.099.500'], ['C22.232', 'E05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The inhibition of endotoxin-induced local inflammation by LDH virus or LDH virus-infected tumors is mediated by interferon. | The footpad swelling reaction induced by local injection of S. marcescens lipopolysaccharide was found to be inhibited in mice given a transplantable tumor (TA3) or cell-free ascitic fluid from tumor-bearing mice. The tumor was shown to contain LDH virus, which is known to cause inapparent persistent infections in mice... | ['Animals', 'Female', 'Immune Sera', 'Inflammation', 'Interferon Type I', 'Kinetics', 'Lipopolysaccharides', 'Mice', 'Mice, Inbred Strains', 'Neoplasms, Experimental', 'Recombinant Proteins', 'Serratia marcescens', 'Togaviridae Infections'] | 3,033,682 | [['B01.050'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['C23.550.470'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['G01.374.661', 'G02.111.490'], ['D09.400.500', 'D09.698.718.450', 'D10.494',... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
B cell depletion with ublituximab reshapes the T cell profile in multiple sclerosis patients. | Multiple sclerosis (MS) is a demyelinating disease of the central nervous system, thought to be mediated by myelin-specific CD4+ T cells. However, B cell depletion has proven to be an effective therapy for MS, but the mechanism is not well understood. This study was designed to determine how B cell depletion changes ly... | ['Adolescent', 'Adult', 'Antibodies, Monoclonal', 'Antigens, CD20', 'Female', 'Humans', 'Immunologic Memory', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Lymphocyte Count', 'Lymphocyte Depletion', 'Male', 'Middle Aged', 'Multiple Sclerosis, Relapsing-Remitting', 'Myeloid Cells', 'T-Lymphocyte Subsets', 'T-Lympho... | 31,077,854 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120', 'D23.101.100.150.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.500'], ['A11.118.637.555.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The cellular response to blood in the vitreous: an ultrastructural study. | The cellular response to whole blood injected into the vitreous cavity of rabbits was studied by transmission and scanning electron microscopy. Inflammatory cell invasion was slow to commence (2--3 days) and was predominantly mononuclear. Although firmly established by 6 days, the cell response remained low-grade with ... | ['Animals', 'Blood', 'Eye Diseases', 'Macrophages', 'Microscopy, Electron', 'Microscopy, Electron, Scanning', 'Neutrophils', 'Phagocytosis', 'Rabbits', 'Thrombosis', 'Vitreous Body'] | 521,869 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of liposome-immunopotentiated exopolysaccharide as a component of an ovine mastitis staphylococcal vaccine. | Experiments on the development of a vaccine against staphylococcal mastitis were carried out in ewes. The vaccine (Spanish patent no. 9200223) has the following components: (i) inactivated (formalinized) bacteria (Staphylococcus aureus and a coagulase-negative staphylococcal species. Staphylococcus simulans) and S. aur... | ['Adjuvants, Immunologic', 'Animals', 'Bacterial Vaccines', 'Female', 'Liposomes', 'Mastitis', 'Polysaccharides, Bacterial', 'Sheep', 'Sheep Diseases', 'Staphylococcal Infections', 'Staphylococcus', 'Staphylococcus aureus'] | 8,165,857 | [['D27.505.696.477.067'], ['B01.050'], ['D20.215.894.135'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['C13.703.844.603', 'C17.800.090.968'], ['D09.698.718', 'D23.050.161.616'], ['B01.050.150.900.649.313.500.380.791'], ['C22.836'], ['C01.150.252.410.868'], ['B03.300.390.400.800.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A comparison of morphine, pethidine and fentanyl in the postsurgical patient-controlled analgesia environment. | This study was designed to evaluate whether there is any scientific basis for clinicians' preferences for selecting opioids for use in patient-controlled analgesia (PCA) and to determine whether there are any patients' preferences for being treated with any of these opioids. Results were obtained for 55 postoperative p... | ['Adult', 'Aged', 'Analgesia, Patient-Controlled', 'Analgesics, Opioid', 'Double-Blind Method', 'Female', 'Fentanyl', 'Humans', 'Male', 'Meperidine', 'Middle Aged', 'Morphine', 'Pain', 'Pain Measurement', 'Patient Satisfaction', 'Postoperative Care'] | 8,867,253 | [['M01.060.116'], ['M01.060.116.100'], ['E03.091.120'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D03.383.621.265'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Self-expanding metallic stent in malignant colonic obstruction]. | About 20% of colorectal cancers are complicated by intestinal obstruction. Self-expanding metallic stents (SEMS) permit desobstruction in over 90% of cases. In palliative setting, employing SEMS reduces hospitalisation time and permanent stoma rate with identical mortality rates compared to surgery. When using SEMS as ... | ['Colonic Diseases', 'Colorectal Neoplasms', 'Hospitalization', 'Humans', 'Intestinal Obstruction', 'Length of Stay', 'Palliative Care', 'Prosthesis Design', 'Stents'] | 24,066,467 | [['C06.405.469.158'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enzymatic, outer membrane proteins and plasmid alterations of starved Vibrio parahaemolyticus and Vibrio alginolyticus cells in seawater. | The marine bacteria Vibrio parahaemolyticus and V. alginolyticus were incubated in seawater for 8 months to evaluate their adaptative responses to starvation. The starved cells showed an altered biochemical and enzymatic profiles, respectively, on Api 20E and Api ZYM systems and an evolution to the filterable minicells... | ['Adaptation, Physiological', 'Bacterial Outer Membrane Proteins', 'Gene Expression Regulation, Bacterial', 'Plasmids', 'Seawater', 'Vibrio alginolyticus', 'Vibrio parahaemolyticus', 'Water Microbiology'] | 19,373,459 | [['G07.025', 'G16.012.500'], ['D12.776.097.120', 'D12.776.543.100'], ['G05.308.300'], ['G05.360.600'], ['G16.500.275.725.500'], ['B03.440.450.900.859.030', 'B03.660.250.830.830.030'], ['B03.440.450.900.859.550', 'B03.660.250.830.830.590'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Propionibacterium acnes infection as an occult cause of postoperative shoulder pain: a case series. | BACKGROUND: Infections after shoulder surgery are potentially devastating complications. Propionibacterium acnes is recognized as a causal agent in shoulder infections. The clinical presentation is usually insidious and nonspecific, but a P. acnes infection could be an occult cause of postoperative shoulder pain.QUESTI... | ['Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Biopsy', 'Colorado', 'Combined Modality Therapy', 'Debridement', 'Female', 'Humans', 'Male', 'Microbiological Techniques', 'Middle Aged', 'Pain Measurement', 'Pain, Postoperative', 'Propionibacterium acnes', 'Retrospective Studies', 'Shoulder Joint', 'Shoulder Pai... | 21,240,577 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['Z01.107.567.875.760.210'], ['E02.186'], ['E04.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Characteristics of responders to cardiac resynchronization therapy: the impact of echocardiographic left ventricular volume. | BACKGROUND: One-third of patients who receive cardiac resynchronization therapy (CRT) are classified as nonresponders. Characteristics of responders to CRT have been studied in multiple clinical trials.HYPOTHESIS: Independent predictors of CRT response may be identified by studying a series of patients in routine clini... | ['Aged', 'Cardiac Resynchronization Therapy', 'Echocardiography', 'Electrocardiography', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Retrospective Studies', 'Stroke Volume'] | 22,886,700 | [['M01.060.116.100'], ['E02.331.200.500'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quality of life in patients submitted to surgical treatment for minor salivary gland neoplasms. | This study was aimed at assessing the quality of life in patients submitted to surgical treatment for minor salivary gland neoplasms (MSGN). Twelve patients (10 women and 2 men, mean age: 49.4 years) with histopathologic diagnosis of pleomorphic adenoma (PA, 3 cases), polymorphous low-grade adenocarcinoma (PLGA, 2 case... | ['Activities of Daily Living', 'Adenocarcinoma', 'Adenoma, Pleomorphic', 'Adult', 'Carcinoma, Adenoid Cystic', 'Carcinoma, Mucoepidermoid', 'Female', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Salivary Gland Neoplasms', 'Salivary Glands, Minor', 'Surveys and Questionnaires'] | 18,060,267 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['C04.557.470.200.025'], ['C04.557.435.090', 'C04.557.470.035.155'], ['M01.060.116'], ['C04.557.470.200.025.220'], ['C04.557.470.200.025.340', 'C04.557.470.590.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.80... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Humanities [K]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cloning, expression, and immunological evaluation of two putative secreted serine protease antigens of Mycobacterium tuberculosis. | Culture filtrate proteins (CFP) of Mycobacterium tuberculosis have been shown to contain immunogenic components that elicit at least partial protective immunity against Mycobacterium infection. To clone genes encoding some of the immunogenic proteins, we made a high-titer rabbit anti-CFP serum and used it to screen an ... | ['Amino Acid Sequence', 'Animals', 'Antigens, Bacterial', 'Bacterial Proteins', 'Base Sequence', 'Blotting, Western', 'Cloning, Molecular', 'Conserved Sequence', 'Humans', 'Interferon-gamma', 'Lymphocyte Activation', 'Molecular Sequence Data', 'Mycobacterium tuberculosis', 'Rabbits', 'Serine Endopeptidases'] | 10,417,166 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.161'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.393.220'], ['G02.111.570.580'], ['B01.050.150.900.649.313.988.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Influence of PacC on the environmental stress adaptability and cell wall components of Ganoderma lucidum. | The transcription factor PacC/Rim101 participates in environmental pH adaptation, development and secondary metabolism in many fungi, but whether PacC/Rim101 contributes to fungal adaptation to environmental stress remains unclear. In our previous study, a homologous gene of PacC/Rim101 was identified, and PacC-silence... | ['Adaptation, Physiological', 'Cell Wall', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Glucosyltransferases', 'Oxidative Stress', 'Reishi', 'Transcription Factors', 'beta-Glucans'] | 31,639,624 | [['G07.025', 'G16.012.500'], ['A11.284.183'], ['D12.776.354'], ['G05.308.330'], ['D08.811.913.400.450.460'], ['G03.673', 'G07.775.750'], ['B01.300.179.120.760.338.700'], ['D12.776.930'], ['D09.698.365.089']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anisotropic protein-protein interactions due to ion binding. | Self-association of proteins is strongly affected by long-range electrostatic interactions caused by equilibrium adsorption of small ions such as protons and multivalent metals. By affecting the molecular net charge, solution pH is thus a widely used parameter to tune stability and phase behavior of proteins. We here r... | ['Ions', 'Protein Binding', 'Proteins'] | 26,162,300 | [['D01.248.497'], ['G02.111.679', 'G03.808'], ['D12.776']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationship between cutaneous pressure threshold and two-point discrimination. | The amount of pressure that should be applied when doing the two-point discrimination test has always been a matter of controversy. The Pressure-specified Sensory Devices permits recording the pressure at which two-point discrimination (2 PD) occurs. The purpose of this study was to investigate the relationship between... | ['Adolescent', 'Adult', 'Aged', 'Carpal Tunnel Syndrome', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Pressure', 'Sensory Thresholds', 'Skin Physiological Phenomena', 'Touch'] | 9,734,846 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520'], ['G01.374.715'], ['F02.463.593.710'], ['G13.750'], ['F02.830.816.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lipopolysaccharide, IFN-gamma, and IFN-beta induce expression of the thiol-sensitive ART2.1 Ecto-ADP-ribosyltransferase in murine macrophages. | Nicotinamide adenosine dinucleotide (NAD) can act as a modulator of multiple immune and inflammatory responses when released into extracellular compartments. These actions of extracellular NAD are largely mediated by a family of mammalian ecto-ADP-ribosyltransferases (ARTs) that covalently modify target extracellular o... | ['ADP Ribose Transferases', 'Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Membrane', 'Cells, Cultured', 'Extracellular Signal-Regulated MAP Kinases', 'Gene Expression Regulation, Enzymologic', 'Inflammation', 'Interferon-beta', 'Interferon-gamma', 'Isoenzymes', 'Lipopolysaccharides', 'Macrophages', 'Mic... | 17,947,697 | [['D08.811.913.400.725.115'], ['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.284.149'], ['A11.251'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['G05.308.320'], ['C23.550.470'], ['D12.644.276.374.440.890.275', 'D12.776.467.374.440.890.275', 'D23.529.374.440.890.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A randomized, placebo-controlled trial of preemptive antifungal therapy for the prevention of invasive candidiasis following gastrointestinal surgery for intra-abdominal infections. | BACKGROUND: Patients undergoing emergency gastrointestinal surgery for intra-abdominal infection are at risk of invasive candidiasis (IC) and candidates for preemptive antifungal therapy.METHODS: This exploratory, randomized, double-blind, placebo-controlled trial assessed a preemptive antifungal approach with micafung... | ['Adolescent', 'Adult', 'Aged', 'Antifungal Agents', 'Biomarkers', 'Candidiasis, Invasive', 'Double-Blind Method', 'Echinocandins', 'Female', 'Humans', 'Intensive Care Units', 'Intraabdominal Infections', 'Lipopeptides', 'Male', 'Micafungin', 'Middle Aged', 'Postoperative Complications', 'Pre-Exposure Prophylaxis', 'Yo... | 26,270,686 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.136'], ['D23.101'], ['C01.150.703.160.175', 'C01.150.703.492.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D12.644.641.311'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tolerance for chronic heat exposure is greater in female than male mice. | PURPOSE: Chronic heat exposure in mice has cellular and physiological effects that improve thermal tolerance [1], but also modifies innate immune responses with potential adverse consequences [2]. While male and female mice are known to respond differently to acute exposure to severe hyperthermia, sex-based differences... | ['Adaptation, Physiological', 'Animals', 'Body Temperature', 'Brain', 'Female', 'Heat-Shock Proteins', 'Heat-Shock Response', 'Hot Temperature', 'Humans', 'Lung', 'Male', 'Mice', 'Sex Characteristics'] | 23,153,218 | [['G07.025', 'G16.012.500'], ['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['A08.186.211'], ['D12.776.580.216'], ['G07.775.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A multi-generational study on low-dose BPA exposure in Wistar rats: effects on maternal behavior, flavor intake and development. | Bisphenol A (BPA) is a common endocrine disruptor found as an environmental and food contaminant. It exerts both developmental and behavioral effects, mainly when exposure occurs in early life. The aim of this study was to determine the multi-generational effects of chronic, human-relevant low-dose exposure to BPA on d... | ['Age Factors', 'Air Pollutants, Occupational', 'Animals', 'Animals, Newborn', 'Benzhydryl Compounds', 'Birth Rate', 'Body Weight', 'Eating', 'Female', 'Flavoring Agents', 'Food Preferences', 'Gestational Age', 'Male', 'Maternal Behavior', 'Phenols', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Rats, Wist... | 24,269,606 | [['N05.715.350.075', 'N06.850.490.250'], ['D27.888.284.101.268'], ['B01.050'], ['B01.050.050.282'], ['D02.455.426.559.389.115'], ['E05.318.308.985.775.500', 'N01.224.935.849.500', 'N06.850.505.400.975.775.500', 'N06.850.520.308.985.775.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.10... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Patient satisfaction in military medicine: status and an empirical test of a model. | The Department of Defense (DoD) is concerned about how well military medical treatment facilities in the military health system perform. Patient expectations, attitudes, and health care use have been examined in numerous studies; the results are fairly consistent. Eligible beneficiaries report moderate satisfaction wit... | ['Adult', 'Aged', 'Female', 'Health Services Research', 'Humans', 'Male', 'Middle Aged', 'Military Medicine', 'Military Personnel', 'Patient Satisfaction', 'United States', 'Veterans'] | 14,529,251 | [['M01.060.116'], ['M01.060.116.100'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.403.500'], ['M01.526.625'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['Z01.107.567.875... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Estrogen Receptor á Deficiency Modulates TLR Ligand-Mediated PDC-TREM Expression in Plasmacytoid Dendritic Cells in Lupus-Prone Mice. | Female lupus-prone NZM2410 estrogen receptor á (ERá)-deficient mice are protected from renal disease and have prolonged survival compared with wild-type littermates; however, the mechanism of protection is unknown. Plasmacytoid dendritic cells (pDCs) and type I IFN drive lupus pathogenesis. Estrogen acting via ERá enha... | ['Animals', 'Cells, Cultured', 'Dendritic Cells', 'Estrogen Receptor alpha', 'Estrogens', 'Female', 'Gene Expression Regulation', 'Immunomodulation', 'Interferon Type I', 'Kidney', 'Lupus Erythematosus, Systemic', 'Mice', 'Mice, Inbred C57BL', 'Receptors, Cell Surface', 'Toll-Like Receptor 9'] | 26,553,076 | [['B01.050'], ['A11.251'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D12.776.826.750.350.174'], ['D27.505.696.399.472.277'], ['G05.308'], ['E02.095.465', 'G12.535'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['A05.810.453'], ['C17.300.480', 'C20.111.590... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pathway of cholesterol biosynthesis in the brain of the neonatal rat. | Suckling rats were killed at various intervals after intraperitoneal injection of acetate-1-(14)C and their brain sterols were analyzed by column, thin-layer, paper, and gas-liquid chromatography. The crude sterol (to which carrier zymosterol was added) was separated by column chromatography into cholesterol, desmoster... | ['Animals', 'Animals, Newborn', 'Brain', 'Brain Chemistry', 'Chemical Phenomena', 'Chemistry', 'Cholesterol', 'Rats', 'Sterols'] | 5,971,045 | [['B01.050'], ['B01.050.050.282'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['G02'], ['H01.181'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.992.635.505.700'], ['D04.210.500.247.808', 'D10.570.938']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Helicopter transport of patients to tertiary care centers after cardiac arrest. | Air transport is commonly used to transfer survivors of cardiac arrest from rural hospitals to large tertiary-care centers, presumably to improve outcome. To examine this issue, a retrospective review of patients stabilized after a cardiac arrest was conducted; 157 transports were reviewed. The mean age of patients was... | ['Adolescent', 'Adult', 'Aged', 'Air Ambulances', 'Child', 'Child, Preschool', 'Female', 'Heart Arrest', 'Hospital Mortality', 'Hospitals, University', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Ohio', 'Retrospective Studies', 'Survival Rate', 'Trauma Centers', 'Treatment Outcome'] | 10,102,309 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['J01.937.285.100.100', 'N02.421.297.879.100.100'], ['M01.060.406'], ['M01.060.406.448'], ['C14.280.383'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['N02.278.020.300.310', 'N02.278.421.639.72... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Expression of a glucose-tolerant beta-glucosidase from Humicola grisea var. thermoidea in Saccharomyces cerevisiae. | A beta-glucosidase gene (bgl4) from Humicola grisea var thermoidea was successfully expressed in Saccharomyces cerevisiae. The recombinant protein (BGL4(Sc)) was initially detected associated with yeast cells and later in the culture medium. BGL4(Sc) showed optimal pH and temperature of 6.0 and 40 degrees C, respective... | ['Ascomycota', 'Hydrogen-Ion Concentration', 'Recombinant Proteins', 'Saccharomyces cerevisiae', 'Temperature', 'beta-Glucosidase'] | 19,669,941 | [['B01.300.107'], ['G02.300'], ['D12.776.828'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D08.811.277.450.420.200.100']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structural diversity in the atomic resolution 3D fingerprint of the titin M-band segment. | In striated muscles, molecular filaments are largely composed of long protein chains with extensive arrays of identically folded domains, referred to as "beads-on-a-string". It remains a largely unresolved question how these domains have developed a unique molecular profile such that each carries out a distinct functio... | ['Connectin', 'Conserved Sequence', 'Genetic Variation', 'Humans', 'Protein Domains', 'Protein Folding'] | 31,856,237 | [['D08.811.913.696.620.682.324', 'D12.776.210.500.246'], ['G02.111.570.580'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['G01.154.651', 'G02.111.688']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pu-erh tea has in vitro anticancer activity in TCA8113 cells and preventive effects on buccal mucosa cancer in U14 cells injected mice in vivo. | Pu-erh tea is a functional tea production in China. The functional effects should be proved. The oral cancer preventive and antimetastatic effects of Pu-erh tea in vitro and in vivo have been studied respectively. Pu-erh tea showed an inhibitory effect on human tongue carcinoma TCA8113 cells proliferation tested by 3-(... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Cell Line, Tumor', 'Cell Proliferation', 'China', 'Down-Regulation', 'Female', 'Humans', 'Interferon-gamma', 'Interleukin-12', 'Interleukin-6', 'Matrix Metalloproteinases', 'Mice', 'Mouth Mucosa', 'Mouth Neoplasms', 'Neoplasms, Experimental', 'Proto-Oncogene Proteins c... | 24,945,996 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['Z01.252.474.164'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Long-term effects of the substituted benzamide derivative amisulpride on baseline and stimulated prolactin levels. | In the present study, we investigated the long-term effects of treatment with amisulpride, a substituted benzamide derivative, as compared with the effects of treatment with flupenthixol, a thioxanthene, on the prolactin levels in schizophrenic patients. After completing 6 weeks of medication with either amisulpride or... | ['Adult', 'Amisulpride', 'Antipsychotic Agents', 'Drug Administration Schedule', 'Female', 'Flupenthixol', 'Humans', 'Male', 'Middle Aged', 'Prolactin', 'Schizophrenia', 'Sulpiride', 'Thyrotropin-Releasing Hormone', 'Time Factors'] | 12,207,145 | [['M01.060.116'], ['D02.065.277.034', 'D02.241.223.100.100.110', 'D02.455.426.559.389.127.085.084'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E02.319.283'], ['D02.886.952.360', 'D03.383.606.460', 'D03.633.300.953.704.360'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The medical dissertation in Germany : A quantitative analysis of promotion regulations in medical faculties]. | BACKGROUND: The medical dissertation represents an independently processed scientific project. In the field of medicine this has for many years displayed the basis for controversial discussions. The aim of the study presented here was to evaluate the prerequisites of all current promotion regulations in German medical ... | ['Academic Dissertations as Topic', 'Academic Performance', 'Education, Medical', 'Faculty, Medical', 'Germany', 'Humans'] | 27,356,924 | [['L01.178.682.389'], ['I02.399.136'], ['I02.358.399'], ['M01.526.485.375', 'M01.526.702.250.373', 'N02.360.375'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
A GUS/luciferase fusion reporter for plant gene trapping and for assay of promoter activity with luciferin-dependent control of the reporter protein stability. | A gene-trapping vector carrying a GUS/Luciferase dual reporter gene was developed to establish an efficient and convenient screening system for T-DNA-based gene trapping in plants. A key feature of this gene trap scheme is to place two different types of reporters, luciferase (Luc) and beta-glucuronidase (GUS), as a fu... | ['Arabidopsis', 'Base Sequence', 'Blotting, Northern', 'Blotting, Western', 'DNA, Bacterial', 'Firefly Luciferin', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genes, Reporter', 'Genome, Plant', 'Glucuronidase', 'Luciferases', 'Models, Genetic', 'Molecular Sequence Data', 'Plants, Genetically Modified', 'Promo... | 17,597,079 | [['B01.650.940.800.575.912.250.157.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.308.212'], ['D02.886.675.298', 'D03.383.129.708.298']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
miR-34a inhibits pancreatic cancer progression through Snail1-mediated epithelial-mesenchymal transition and the Notch signaling pathway. | Epithelial-mesenchymal transition (EMT) and Notch signaling are important for the growth and invasion of pancreatic cancer, which is a leading cause of cancer-related deaths worldwide. miR-34a has been shown to play pivotal roles in the progression of several types of cancer. However, little is known about the regulato... | ['Animals', 'Apoptosis', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Disease Progression', 'Epithelial-Mesenchymal Transition', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Mice, Inbred BALB C', 'Mice, Nude', 'MicroRNAs', 'Pancreatic Neoplasms', 'RNA, Small Interfering', 'Receptor, Notch1', 'Sig... | 28,145,431 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C23.550.291.656'], ['G04.356.500'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complement component C5a predicts future cardiovascular events in patients with advanced atherosclerosis. | AIMS: Complement activation occurs in atherosclerotic lesions, and particularly complement component C5a exerts potent chemotactic and proinflammatory effects. However, it is yet unknown, whether plasma levels of C5a may predict cardiovascular risk. The aim of this study was to examine whether plasma levels of the comp... | ['Aged', 'Atherosclerosis', 'Biomarkers', 'Complement Activation', 'Complement C5a', 'Female', 'Humans', 'Male', 'Peripheral Vascular Diseases', 'Prospective Studies', 'Risk Factors'] | 15,917,276 | [['M01.060.116.100'], ['C14.907.137.126.307'], ['D23.101'], ['G12.274'], ['D12.776.124.486.274.024.270', 'D12.776.124.486.274.450.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.617'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.740.600.800.725'... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of acorn size and storage duration on moisture content, germination and survival of Quercus petraea (Mattuschka). | This study was conducted to evaluate how acom size (small, medium and large) and acorn storage duration (0, 5 and 17 months) influenced Quercus petraea (Mattuschka) moisture content and germination. Acorn size and storage duration did not significantly affect acorn moisture content, but they significantly affected acor... | ['Germination', 'Quercus', 'Seedlings', 'Seeds', 'Time Factors', 'Water'] | 21,047,006 | [['G07.345.625.249', 'G15.357'], ['B01.650.940.800.575.912.250.859.750.300.500'], ['A18.550', 'B01.650.819'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['G01.910.857'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Oxytocin does not contribute to the effects of cervical dilation on progesterone secretion and embryonic development in mares. | The aim of the present study was, to investigate the effects of oxytocin administration on Day 7 post-ovulation on progesterone secretion, pregnancy rate and embryonic growth in mares. Endogenous stimulation of oxytocin release was compared to the administration of native oxytocin or the long-acting oxytocin analogue c... | ['Animals', 'Cervix Uteri', 'Cross-Over Studies', 'Embryonic Development', 'Female', 'Horses', 'Oxytocics', 'Oxytocin', 'Pregnancy', 'Pregnancy Rate', 'Progesterone', 'Random Allocation', 'Time Factors'] | 16,769,107 | [['B01.050'], ['A05.360.319.679.256'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['B01.050.150.900.649.313.984.235.472'], ['D27.505.696.875.737', 'D27.505.954.705.737'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['G08.686.784.769'], ... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Multiple oncocytic cystadenoma with intraluminal crystalloids in parotid gland: case report. | Oncocytic cystadenoma is a benign tumor of salivary glands, histologically characterized by multicystic growth of the oncocytic epithelial lining. Crystals in different shapes and nature associate oncocytic type of salivary gland neoplasms. An 82 year-old woman with right parotideal mass had an operation of superficial... | ['Aged, 80 and over', 'Cystadenoma', 'Female', 'Humans', 'Parotid Gland', 'Parotid Neoplasms'] | 25,501,093 | [['M01.060.116.100.080'], ['C04.557.470.035.320', 'C04.557.470.590.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.549.760.464'], ['C04.588.443.591.824.695', 'C07.465.530.824.695', 'C07.465.815.470.770', 'C07.465.815.718.589']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Heterogeneity in high-risk prostate cancer treated with high-dose radiation therapy and androgen deprivation therapy. | BACKGROUND: Our aim was to assess the heterogeneity of high-risk (HR) prostate cancer managed with high-dose external beam radiotherapy (EBRT) with androgen deprivation therapy (ADT).METHODS: We identified 547 patients who were treated with modern EBRT from 1997 to 2013, of whom 98% received ADT. We analyzed biochemica... | ['Aged', 'Aged, 80 and over', 'Androgen Antagonists', 'Combined Modality Therapy', 'Gonadotropin-Releasing Hormone', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Risk Assessment'] | 28,764,689 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D06.347.065', 'D27.505.696.399.450.065'], ['E02.186'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Persistent organohalogen contaminant burdens in Antarctic krill (Euphausia superba) from the eastern Antarctic sector: a baseline study. | A baseline for persistent organohalogen compound (POC) accumulation in the Antarctic keystone species, Antarctic krill (Euphausia superba) has been established for a 50 degrees longitudinal range of the eastern Antarctic sector. Samples of adult krill, caught from 12 sites distributed between 30 degrees and 80 degrees ... | ['Animals', 'Antarctic Regions', 'Body Burden', 'Data Collection', 'Environmental Monitoring', 'Euphausiacea', 'Hydrocarbons, Halogenated', 'Water Pollutants, Chemical'] | 18,848,720 | [['B01.050'], ['Z01.158'], ['E05.799.638.231', 'N06.850.460.200'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.500.131.365.250'], ['D02.455.526'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1. | TRF2 and TRF1 are a key component in shelterin complex that associates with telomeric DNA and protects chromosome ends. BRM is a core ATPase subunit of SWI/SNF chromatin remodeling complex. Whether and how BRM-SWI/SNF complex is engaged in chromatin end protection by telomeres is unknown. Here, we report that depletion... | ['Chromosomal Proteins, Non-Histone', 'Genomic Instability', 'HEK293 Cells', 'HeLa Cells', 'Hep G2 Cells', 'Heterochromatin', 'Humans', 'Promoter Regions, Genetic', 'Telomere', 'Telomeric Repeat Binding Protein 1', 'Telomeric Repeat Binding Protein 2', 'Transcription Factors'] | 32,502,208 | [['D12.776.660.235', 'D12.776.664.235'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['A11.251.860.180.432', 'A11.436.348.500'], ['A11.284.430.106.279.345.190.160.180.383', 'D12.776.664.224.466', 'G05.360.160.180.3... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence that muscarinic receptors in islet cells are not coupled functionally to adenylate cyclase through the inhibitory guanine nucleotide binding protein (Ni). | The effect of muscarinic agonist on adenylate cyclase was investigated in neonatal islet cells and in a clonal pituitary cell line (GH4C1) following labelling of the intracellular ATP pool with [2,8 3H]adenine. In islet cells carbamylcholine was without effect on basal or glucagon-stimulated adenylate cyclase activity,... | ['Adenylate Cyclase Toxin', 'Adenylyl Cyclases', 'Carbachol', 'Cells, Cultured', 'GTP-Binding Proteins', 'Humans', 'In Vitro Techniques', 'Islets of Langerhans', 'Pertussis Toxin', 'Receptors, Muscarinic', 'Virulence Factors, Bordetella'] | 3,133,298 | [['D08.811.520.650.200.040', 'D23.946.123.946.040', 'D23.946.896.980.040'], ['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['A11.251'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A03.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phenotypic and genotypic characterization of human immunodeficiency virus type 1 CRF07_BC strains circulating in the Xinjiang Province of China. | BACKGROUND: HIV-1 CRF07_BC recombinant previously circulated mainly among the intravenous drug users (IDUs) in Xinjiang province of China and is currently spreading in the entire country. The aim of this study is to characterize the genotypic and phenotypic properties of HIV-1 CRF07_BC isolates in comparison with those... | ['Adult', 'Amino Acid Sequence', 'China', 'Cluster Analysis', 'Drug Users', 'Genotype', 'Glycosylation', 'HIV Envelope Protein gp120', 'HIV Infections', 'HIV-1', 'Humans', 'Middle Aged', 'Molecular Sequence Data', 'Phylogeny', 'Receptors, HIV', 'Sequence Homology', 'Substance Abuse, Intravenous', 'Virus Attachment', 'V... | 19,442,296 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['Z01.252.474.164'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['M01.169'], ['G05.380'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.776.964.970.880.325.164.2... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Study of the coordination abilities of stibine ligands to gold(I). | The reaction of [AuCl(tht)] (tht = tetrahydrothiophene) with SbMes(n)Ph(3-n) (n = 3 (1), 2 (2), 1 (3)) produces the 1:1 adducts [AuCl(SbMes(n)Ph(3-n))] (n = 3 (4), 2 (5), 1 (6)), with a Sb-Au-Cl environment, regardless of the molar ratio used (1:1 to 1:4). Addition of the same stibines to [Au(tht)(2)]ClO(4) (molar rati... | ['Antimony', 'Crystallography, X-Ray', 'Gold', 'Ligands', 'Models, Molecular', 'Organometallic Compounds'] | 20,540,566 | [['D01.268.513.124', 'D01.268.556.050', 'D01.552.544.050'], ['E05.196.309.742.225'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D27.720.470.480'], ['E05.599.595'], ['D02.691']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cryptosporidium parvum in Korea: prevalence in individuals residing in three major river valleys and genetic characteristics of the isolates. | Cryptosporidiosis is a diarrheal illness caused by apicomplexa parasite Cryptosporidium spp. In this study, to examine the overall infection status of Cryptosporidium spp. in individuals residing in southern parts of Korea, eight counties around Yeongsan, Seomjin and Nakdong River valleys was surveyed. The investigatio... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Animals', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Cryptosporidiosis', 'Cryptosporidium parvum', 'DNA, Protozoan', 'Feces', 'Female', 'Humans', 'Infant', 'Korea', 'Male', 'Middle Aged', 'Parasite Egg Count', 'Polymerase Chain Reaction'... | 19,942,816 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['C01.610.432.269', 'C01.610.701.688.235', 'C01.610.75... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Antifungal activity of plumericin and isoplumericin. | This study evaluated the in vitro antifungal activity of the chloroform extract of Plumeria bicolor and its phytoconstituents plumericin and isoplumericin against Candida species and Cryptococcus neoformans by measuring the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC). Plumericin's ... | ['Antifungal Agents', 'Apocynaceae', 'Candida', 'Cryptococcus neoformans', 'Indenes', 'Iridoids', 'Microbial Sensitivity Tests', 'Plant Extracts'] | 22,224,260 | [['D27.505.954.122.136'], ['B01.650.940.800.575.912.250.456.500'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['D02.455.426.559.847.486', 'D04.615.486'], ['D02.455.426.392.368.450.675.500', 'D02.455.849.575.188.500', 'D03.383.663.491'], ['E01.370.225.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Who calls the shots in tobacco control policy? Policy monopolies of pro and anti-tobacco interest groups across six European countries. | BACKGROUND: One of the factors influencing variation in tobacco control policies across European countries is the relative policy dominance of pro and anti-tobacco control interest groups. Scholars investigating this power balance have predominantly conducted single country case studies. This study aims to explore and ... | ['Europe', 'Health Policy', 'Humans', 'Policy Making', 'Qualitative Research', 'Stakeholder Participation', 'Tobacco Use'] | 31,226,963 | [['Z01.542'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.742'], ['H01.770.644.241.850'], ['I01.738.805', 'I03.743'], ['F01.145.958']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Palliative hemiskeletal irradiation for widespread metastatic prostate cancer: a comparison of single dose and fractionated regimens. | Between 1986 and 1987 patients with hormone refractory metastatic adenocarcinoma of the prostate were treated with hemiskeletal irradiation. One group of 15 patients was treated with a fractionated regimen of 2500-3000 cGy in 9 to 10 fractions. A second group of 14 patients received a single dose of 600 cGy or 800 cGy ... | ['Adenocarcinoma', 'Aged', 'Aged, 80 and over', 'Bone Neoplasms', 'Clinical Trials as Topic', 'Humans', 'Male', 'Palliative Care', 'Prostatic Neoplasms', 'Radiotherapy Dosage'] | 2,480,941 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.149', 'C05.116.231'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.666', 'N02.421.585.666'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Soil Carbon Response to Projected Climate Change in the US Western Corn Belt. | The western US Corn Belt is projected to experience major changes in growing conditions due to climate change over the next 50 to 100 yr. Projected changes include increases in growing season length, number of high temperature stress days and warm nights, and precipitation, with more heavy rainfall events. The impact t... | ['Agriculture', 'Carbon', 'Climate Change', 'Crops, Agricultural', 'Soil', 'Zea mays'] | 30,025,056 | [['J01.040'], ['D01.268.150'], ['G16.500.175.374'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.650.940.800.575.912.250.822.966']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Examination of the role of Mycoplasma bovis in bovine pneumonia and a mathematical model for its evaluation. | The authors screened 34 large cattle herds for the presence of Mycoplasma bovis infection by examining slaughtered cattle for macroscopic lung lesions, by culturing M. bovis from lung lesions and at the same time by testing sera for the presence of antibodies against M. bovis. Among the 595 cattle examined, 33.9% had p... | ['Animals', 'Antibodies, Bacterial', 'Cattle', 'Cattle Diseases', 'Hungary', 'Lung', 'Models, Biological', 'Mycoplasma Infections', 'Mycoplasma bovis', 'Pneumonia', 'Seroepidemiologic Studies'] | 15,595,278 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['Z01.542.248.495'], ['A04.411'], ['E05.599.395'], ['C01.150.252.400.610.610'], ['B03.440.860.580.553.553.200'], ['C01.748.610', 'C08.381.677', 'C08.730.610'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/â-Catenin Pathway. | BACKGROUND/AIMS: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in clinical practice to relieve fever and pain. Aspirin, as a representative NSAID, has been widely used in the treatment of tendinopathy. Some reports have demonstrated that aspirin can induce apoptosis in cancer cells. However, evidence... | ['Animals', 'Apoptosis', 'Aspirin', 'Caspase 3', 'Cyclooxygenase 2', 'Gene Expression Regulation', 'Glycogen Synthase Kinase 3', 'Male', 'Mitochondria', 'Nitrobenzenes', 'Proto-Oncogene Proteins c-bcl-2', 'Rats', 'Rats, Sprague-Dawley', 'Stem Cells', 'Sulfonamides', 'Tendons', 'Wnt Signaling Pathway', 'Wnt3A Protein', ... | 30,415,260 | [['B01.050'], ['G04.146.954.035'], ['D02.455.426.559.389.657.410.595.176'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.600.720.750'], ['G05.308'], ['D05.500.117.875', 'D08.811.913.696.620.682.700.429.500', 'D08.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term survival of dialysis patients with bacterial endocarditis in the United States. | BACKGROUND: The incidence of bacterial endocarditis is much greater in long-term dialysis patients compared with the general population, and chronic kidney disease has been postulated as an independent host-related risk factor. Limited data are available on the long-term survival of dialysis patients with endocarditis.... | ['Aged', 'Cohort Studies', 'Endocarditis, Bacterial', 'Female', 'Hospitalization', 'Humans', 'Incidence', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Retrospective Studies', 'Survival Rate', 'Time', 'United States'] | 15,558,529 | [['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The characteristics and surgical outcomes of medial rectus recessions in Graves' ophthalmopathy. | PURPOSE: To evaluate the clinical characteristics and surgical outcomes of medial rectus (MR) recessions in patients with Graves' ophthalmopathy.PATIENTS AND METHODS: The clinical records of 32 patients with Graves' ophthalmopathy who underwent MR recessions with adjustable sutures for restrictive esotropia were review... | ['Adult', 'Aged', 'Aged, 80 and over', 'Esotropia', 'Female', 'Graves Ophthalmopathy', 'Humans', 'Male', 'Middle Aged', 'Oculomotor Muscles', 'Ophthalmologic Surgical Procedures', 'Suture Techniques', 'Treatment Outcome'] | 17,410,960 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.292.562.887.300', 'C11.590.810.400'], ['C11.270.240', 'C11.675.349.500.500', 'C16.320.347', 'C19.874.283.605.500', 'C19.874.397.370.500', 'C20.111.555.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567.700'], [... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Factors associated with recurrent bacterial vaginosis. | OBJECTIVE: To determine whether menstrual abnormalities, multiple personal behaviors and some contraceptive methods, all of which have been described as potential causes of single episodes of bacterial vaginosis (BV), are associated with recurrent bacterial vaginosis (RBV).STUDY DESIGN: This was a retrospective, case-c... | ['Adolescent', 'Adult', 'African Americans', 'Case-Control Studies', 'Contraception', 'European Continental Ancestry Group', 'Female', 'Health Behavior', 'Health Surveys', 'Humans', 'Male', 'Odds Ratio', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Sexual Behavior', 'Sexual Partners', 'Urban Population', 'Va... | 20,337,209 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.875.194'], ['M01.686.508.400'], ['F01.145.488'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preference for an estrous female over a non-estrous female evinced by female rats requires dihydrotestosterone plus estradiol. | The effects were studied of long-term treatment with testosterone metabolites (dihydrotestosterone. DHT, and estradiol, E2, in sc Silastic implants) on preference behavior of ovariectomized female rats for an estrous female over a non-estrous female. For measuring this behavior a residential plus-maze was used which ha... | ['Animals', 'Dihydrotestosterone', 'Drug Synergism', 'Estradiol', 'Estrus', 'Female', 'Ovariectomy', 'Progesterone', 'Rats', 'Rats, Inbred Strains', 'Sexual Behavior, Animal'] | 2,606,463 | [['B01.050'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['G07.690.773.968.477'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Purification and characterization of a smooth muscle myosin phosphatase from turkey gizzards. | A phosphoprotein phosphatase that dephosphorylates smooth muscle myosin has been purified to apparent homogeneity from turkey gizzards. Smooth muscle phosphatase (SMP) IV has a molecular weight of 150,000 as determined by gel filtration on a Sephadex G-200 column and is composed of two subunits (Mr = 58,000 and 40,000)... | ['Animals', 'Calcium', 'Gizzard, Avian', 'Kinetics', 'Magnesium', 'Muscle, Smooth', 'Myosin-Light-Chain Phosphatase', 'Phosphoprotein Phosphatases', 'Substrate Specificity', 'Turkeys'] | 2,995,373 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A13.853.355'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['A02.633.570', 'A10.690.467'], ['D08.811.277.352.650.625.475'], ['D08.811.277.352.650.625'], ['G02.111.835'], ['B01.050.150.900.248.350.800', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Smart pH-responsive polymeric micelles for programmed oral delivery of insulin. | The development of intelligent oral drug delivery carrier aiming at efficiently bring insulin to intestine is of great significance for diabetes mellitus therapy. In the present study, a series of amphiphilic pH-sensitive block copolymer poly(methyl methacrylate-co-methacrylicacid)-b-poly(2-amino ethyl methacrylate) [P... | ['Administration, Oral', 'Caco-2 Cells', 'Cell Survival', 'Drug Carriers', 'Drug Delivery Systems', 'Humans', 'Hydrogen-Ion Concentration', 'Hypoglycemic Agents', 'Insulin', 'Micelles', 'Molecular Structure', 'Particle Size', 'Polymers', 'Proton Magnetic Resonance Spectroscopy', 'Spectroscopy, Fourier Transform Infrare... | 31,445,358 | [['E02.319.267.100'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['G04.346'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D05.374', 'D26.255.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
mTOR direct crosstalk with STAT5 promotes de novo lipid synthesis and induces hepatocellular carcinoma. | Hepatocellular carcinoma (HCC) can be the last step of nonalcoholic fatty liver disease (NAFLD) evolution, and the main characteristic of NAFLD is alteration in lipid metabolism. However, the mechanisms of abnormal lipid metabolism in NAFLD and HCC progression are yet to be identified. Here, we demonstrate that liver-s... | ['Acetyltransferases', 'Animals', 'Carcinoma, Hepatocellular', 'Diet, High-Fat', 'Disease Models, Animal', 'Fatty Acid Synthase, Type I', 'Gene Expression Regulation, Neoplastic', 'Hep G2 Cells', 'Hepatocytes', 'Humans', 'Lipid Metabolism', 'Lipids', 'Liver', 'Liver Neoplasms', 'Mechanistic Target of Rapamycin Complex ... | 31,409,773 | [['D08.811.913.050.134'], ['B01.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G07.203.650.240.267'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D08.811.277.352.897.387.100', 'D08.811.520.241.300.287.099', 'D08.811.641.758', 'D08.811.682.047.820.196.500.099', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Health examination of asylum seekers: A nationwide analysis of state policies in Germany : § 62 of the asylum law]. | BACKGROUND: A health examination of newly arrived asylum seekers, aimed at detecting infectious diseases and preventing disease outbreaks in accommodation facilities, is mandated by national law in all German states. Due to the decentralized German federal system, different state policies are in place and lead to subst... | ['Emigration and Immigration', 'Germany', 'Government Regulation', 'Health Policy', 'Mandatory Testing', 'Refugees', 'State Government'] | 27,885,404 | [['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['Z01.542.315'], ['I01.880.604.394', 'N03.706.358'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I01.880.604.622.500', 'N03.706.657.500', 'N06.850.780.200.550', 'N06.850.780.500.412'], ['M01.755'], ['I01.409... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Medicinal plants popularly used in the Xing? region - a semi-arid location in Northeastern Brazil. | The aim of this study was to identify plant species among the diverse flora of the caatinga ecosystem that are used therapeutically. Research was undertaken in the municipalities of Piranhas and Delmiro Gouveia, in the Xing? region (state of Alagoas, NE Brazil). In order to identify the medicinal plants used in this re... | ['Adult', 'Brazil', 'Databases, Factual', 'Desert Climate', 'Female', 'Health Knowledge, Attitudes, Practice', 'Herbal Medicine', 'Humans', 'Interviews as Topic', 'Male', 'Medicine, Traditional', 'Middle Aged', 'Plant Extracts', 'Plants, Medicinal', 'Surveys and Questionnaires', 'Young Adult'] | 16,556,305 | [['M01.060.116'], ['Z01.107.757.176'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['F01.100.150.500', 'N05.300.150.410'], ['H01.158.273.118.598.500', 'H01.158.703.060.500', 'H02.628.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', '... | ['Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Soc... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
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