Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ceramic bearings for total hip arthroplasty have high survivorship at 10 years. | BACKGROUND: Ceramic bearings were introduced to reduce wear and increase long-term survivorship of total hip arthroplasty. In a previous study comparing ceramic with metal-on-polyethylene at 5 to 8 years, we found higher survivorship and no osteolysis for the ceramic bearings.QUESTIONS/PURPOSES: We asked whether cerami... | ['Adult', 'Aged', 'Aluminum Oxide', 'Arthroplasty, Replacement, Hip', 'Chromium Alloys', 'Female', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Joint Instability', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Noise', 'Osteolysis', 'Polyethylene', 'Proportional Hazards Models', 'Prosthesis Design', 'Prosthesis Failure'... | 21,918,802 | [['M01.060.116'], ['M01.060.116.100'], ['D01.056.050', 'D01.650.550.050'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D01.220.175', 'D01.552.033.182', 'D25.058.224', 'D25.339.208.224', 'J01.637.051.058.224', 'J01.637.051.339.208.224'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.050.150.90... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
An examination of the effects of intra and inter-individual changes in wellbeing and mental health on self-rated health in a population study of middle and older-aged adults. | PURPOSE: Self-rated health is frequently used as an indicator of health and quality of life in epidemiological studies. While the association between self-rated health and negative mental health is well established, associations with indictors of positive wellbeing are less clear. Data from the Dynamic Analyses to Opti... | ['Aged', 'Aged, 80 and over', 'Aging', 'Female', 'Health Promotion', 'Health Status', 'Health Surveys', 'Humans', 'Individuality', 'Male', 'Mental Health', 'Middle Aged', 'Personal Satisfaction', 'Quality of Life', 'Self Report', 'Surveys and Questionnaires'] | 24,632,783 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['I02.233.332.445', 'N02.421.726.407.579'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F02.418', ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Partner services as targeted HIV screening--changing the paradigm. | OBJECTIVES: The San Francisco Department of Public Health (SFDPH) has the goal of offering HIV partner services (PS) to all individuals newly diagnosed with HIV in San Francisco. However, measuring the potential impact of these services is challenging. Building on an existing syphilis partner notification program, we d... | ['AIDS Serodiagnosis', 'HIV Infections', 'Humans', 'Public Health Administration', 'San Francisco', 'Sexual Partners'] | 24,385,649 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.794'], ['Z0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Spectral EEG correlates of dream recall. | Recent studies have shown that dreaming is not limited to rapid eye movement (REM) sleep, but can be found to varying degrees in any stage of sleep. This study attempted to quantify the EEG correlations of dreaming during Stage 2 sleep. Six normal volunteers were studied for 24 nights in the sleep laboratory. Electroen... | ['Adolescent', 'Adult', 'Dreams', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Memory', 'Mental Recall', 'Models, Neurological', 'Sleep Initiation and Maintenance Disorders', 'Sleep Stages'] | 3,730,456 | [['M01.060.057'], ['M01.060.116'], ['F02.463.188.634.309', 'F02.830.855.268'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['E05.599.395.642'], ['C10.886.425.800.800', 'F03.870.400.800.800'], ['F02.830.855.796', 'G11.561.803.754'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Myocardial infarction secondary to dipyridamole overdose. | A case of myocardial infarction secondary to dipyridamole overdose is described in a 62-year-old woman with longstanding angina. Therapeutic doses of dipyridamole are associated with reversible myocardial ischaemia in a proportion of patients but serious adverse events are rare (Homma et al., 1987). To our knowledge th... | ['Dipyridamole', 'Drug Overdose', 'Female', 'Humans', 'Middle Aged', 'Myocardial Infarction'] | 1,567,532 | [['D03.383.742.175'], ['C25.775.383', 'E02.319.306.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transcriptome profiling of citrus fruit response to huanglongbing disease. | Huanglongbing (HLB) or "citrus greening" is the most destructive citrus disease worldwide. In this work, we studied host responses of citrus to infection with Candidatus Liberibacter asiaticus (CaLas) using next-generation sequencing technologies. A deep mRNA profile was obtained from peel of healthy and HLB-affected f... | ['Analysis of Variance', 'Carbohydrate Metabolism', 'Citrus', 'Computational Biology', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'High-Throughput Nucleotide Sequencing', 'Models, Biological', 'Photosynthesis', 'Plant Diseases', 'Plant Growth Regulators', 'Protein Folding', 'Protein Stability', '... | 22,675,433 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G02.111.158', 'G03.191'], ['B01.650.940.800.575.912.250.875.177'], ['H01.158.273.180', 'L01.313.124'], ['E05.393.332'], ['G05.308.375'], ['E05.393.760.319'], ['E05.599.395'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: Report of two cases. | INTRODUCTION: Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare disorder characterized by a proliferation of neuroendocrine cells within the lung. It is classically described as a disease with persistent cough, dyspnea and wheezing in non-smoker middle aged females. CT of the chest reveal... | ['Aged', 'Asthma', 'Bronchoscopy', 'Cigarette Smoking', 'Cough', 'Diagnosis, Differential', 'Dyspnea', 'Female', 'Humans', 'Hyperplasia', 'Lung', 'Middle Aged', 'Multiple Pulmonary Nodules', 'Neuroendocrine Cells', 'Positron-Emission Tomography', 'Precancerous Conditions', 'Respiratory Function Tests', 'Tomography, X-R... | 29,789,142 | [['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['F01.145.805.375.750', 'F01.145.958.875.750'], ['C08.618.248', 'C23.888.852.293'], ['E01.171'], ['C08.618.326', 'C23.888.852.371'], ['B01.050... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress. | In fission yeast, orthologs of mammalian SREBP and Scap, called Sre1 and Scp1, monitor oxygen-dependent sterol synthesis as a measure of cellular oxygen supply. Under low oxygen conditions, sterol synthesis is inhibited, and Sre1 cleavage is activated. However, the sterol signal for Sre1 activation is unknown. In this ... | ['Gene Expression Regulation, Fungal', 'Lanosterol', 'Mutation', 'Oxidative Stress', 'Oxygen', 'Schizosaccharomyces', 'Sterol Regulatory Element Binding Proteins', 'Sterols'] | 17,595,166 | [['G05.308.330'], ['D02.455.849.919.383', 'D04.210.500.247.222.222.347.557', 'D04.210.500.247.808.607', 'D10.570.938.590'], ['G05.365.590'], ['G03.673', 'G07.775.750'], ['D01.268.185.550', 'D01.362.670'], ['B01.300.107.797', 'B01.300.930.720'], ['D12.776.260.103.500.750', 'D12.776.260.108.092.750', 'D12.776.930.125.500... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chromosome evolution in bats as revealed by FISH: the ongoing search for the ancestral chiropteran karyotype. | Chiroptera, the second largest order of mammals, comprises more than 1,000 species in 18 highly morphologically diverse families. Chromosome painting with human probes has been applied to 10 bat species from 8 families. Except for the combination 10/12pq/22q, all syntenic segmental associations proposed for the mammali... | ['Animals', 'Chiroptera', 'Chromosome Inversion', 'Chromosome Painting', 'Chromosomes, Human', 'Chromosomes, Mammalian', 'Evolution, Molecular', 'Humans', 'In Situ Hybridization, Fluorescence', 'Karyotype', 'Phylogeny', 'Species Specificity', 'Translocation, Genetic'] | 22,678,038 | [['B01.050'], ['B01.050.150.900.649.313.937'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['E01.370.225.500.620.670.325.350.125', 'E01.370.225.750.600.670.325.350.125', 'E05.200.500.620.670.325.350.125', 'E05.200.750.600.670.325.350.125', 'E05.393.285.350.125', 'E05.393.661.47... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pituitary cellular hypersensitivity in idiopathic hypopituitarism. | Lymphocyte transformation in response to a saline extract of human pituitary was used to evaluate anti-pituitary immunity in patients with idiopathic hypopituitarism. Nine normal subjects and three children with idiopathic hypopituitarism were studied. Lymphocytes of one patient were significantly reactive to pituitary... | ['Adolescent', 'Adult', 'Autoimmune Diseases', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Hypopituitarism', 'Lymphocyte Activation', 'Male', 'Pituitary Gland'] | 6,723,081 | [['M01.060.057'], ['M01.060.116'], ['C20.111'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.617.738.300', 'C19.700.482'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['A06.300.747', 'A06.688.357.750', 'A08.186.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of severe acute respiratory syndrome-associated coronavirus infection by equine neutralizing antibody in golden Syrian hamsters. | Equine anti-severe acute respiratory syndrome-associated coronavirus F(ab')(2) has been verified to protect mice from infection with severe acute respiratory syndrome-associated coronavirus (SARS-CoV). However, before potential clinical application, the antibody needs to be tested in as many animal models as possible t... | ['Administration, Intranasal', 'Animals', 'Antibodies, Viral', 'Cricetinae', 'Horses', 'Immunoglobulin Fab Fragments', 'Mesocricetus', 'Neutralization Tests', 'Polymerase Chain Reaction', 'Severe Acute Respiratory Syndrome'] | 17,425,434 | [['E02.319.267.120.655.500'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.984.235.472'], ['D12.644.541.500.650', 'D12.776.124.486.485.680.650', 'D12.776.124.790.651.680.650', 'D12.776.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ventricular septal defect secondary to penetrating trauma without pericardial effusion. | Incidence of penetrating cardiac trauma is on the rise. With improved trauma care, an increasing number of these patients arrive at the hospital alive. An unusual case of penetrating cardiac trauma is presented that highlights the importance of thorough echocardiographic assessment of such patients. | ['Adult', 'Cardiac Surgical Procedures', 'Echocardiography, Transesophageal', 'Electrocardiography', 'Heart Injuries', 'Heart Septal Defects, Ventricular', 'Humans', 'Male', 'Treatment Outcome', 'Wounds, Stab'] | 14,631,479 | [['M01.060.116'], ['E04.100.376', 'E04.928.220'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C26.891.375'], ['C14.240.400.560.540', 'C14.280.400.560.540', 'C16.131.240.400.560.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Benchmarking CIN 3+ risk as the basis for incorporating HPV and Pap cotesting into cervical screening and management guidelines. | OBJECTIVE: In 2012, the US Preventive Services Task Force (USPSTF) and a consensus of 25 organizations endorsed concurrent cytology and human papillomavirus (HPV) testing ("cotesting") for cervical cancer screening. Past screening and management guidelines were implicitly based on risks defined by Pap-alone, without co... | ['Adult', 'Benchmarking', 'Cervical Intraepithelial Neoplasia', 'Female', 'Humans', 'Mass Screening', 'Middle Aged', 'Papillomavirus Infections', 'Uterine Cervical Neoplasms', 'Vaginal Smears', 'Virology'] | 23,519,302 | [['M01.060.116'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['C04.557.470.200.240.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580',... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. | Ultraviolet light has been linked with the development of human skin cancers. Such cancers often exhibit mutations in the p53 tumor suppressor gene. Ligation-mediated polymerase chain reaction was used to analyze at nucleotide resolution the repair of cyclobutane pyrimidine dimers along the p53 gene in ultraviolet-irra... | ['Cells, Cultured', 'DNA Repair', 'Exons', 'Genes, p53', 'HeLa Cells', 'Humans', 'Mutation', 'Phosphoglycerate Kinase', 'Polymerase Chain Reaction', 'Pyrimidine Dimers', 'Skin', 'Skin Neoplasms', 'Ultraviolet Rays'] | 8,128,225 | [['A11.251'], ['G02.111.222', 'G05.219'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['D08.811.913.696.630.700'], ['E05.393.620.5... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Targeted Therapy for Metastatic Urothelial Cancer: A Work in Progress. | The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of... | ['Humans', 'Male', 'Middle Aged', 'Molecular Targeted Therapy', 'Neoplasm Metastasis', 'Receptor, ErbB-2', 'Receptor, Fibroblast Growth Factor, Type 3', 'Receptors, Fibroblast Growth Factor', 'Urologic Neoplasms', 'Urothelium'] | 27,161,964 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.319.574'], ['C04.697.650', 'C23.550.727.650'], ['D08.811.913.696.620.682.725.400.009.400', 'D12.776.543.750.630.009.400', 'D12.776.543.750.750.400.074.400', 'D12.776.624.664.700.642', 'D23.050.301.500.600.700', 'D23.050.705.552.600.550', 'D23.... | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple sclerosis among first- and second-generation immigrants in Denmark: a population-based cohort study. | Multiple sclerosis is a disease with a highly variable incidence worldwide. While knowledge about multiple sclerosis risk factors has grown over the years, the aetiology of multiple sclerosis has still not been fully established. We examined multiple sclerosis incidence rates among first-generation immigrants in Denmar... | ['Adolescent', 'Adult', 'Age Distribution', 'Child', 'Cohort Studies', 'Denmark', 'Emigrants and Immigrants', 'Female', 'Humans', 'Incidence', 'Male', 'Multiple Sclerosis', 'Registries', 'Risk Factors'] | 31,081,503 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.816.124'], ['M01.189'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', ... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
An unusually long-lived antisense RNA in plasmid copy number control: in vivo RNAs encoded by the streptococcal plasmid pIP501. | The main regulator of pIP501 replication is an antisense RNA (RNAIII) that induces transcriptional attenuation of the essential RNAII. Previous studies identified the termination point in vivo and demonstrated attenuation in vitro. This in vivo analysis confirms the appearance of attenuated RNAII dependent on RNAIII. H... | ['Bacterial Proteins', 'Base Sequence', 'DNA-Binding Proteins', 'Half-Life', 'Molecular Sequence Data', 'Mutation', 'Nucleic Acid Conformation', 'Plasmids', 'RNA', 'RNA, Antisense', 'Streptococcus', 'Trans-Activators', 'Transcription, Genetic'] | 8,551,520 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.260'], ['G01.910.405'], ['L01.453.245.667'], ['G05.365.590'], ['G02.111.570.820.486', 'G05.360.580'], ['G05.360.600'], ['D13.444.735'], ['D13.150.650', 'D13.444.600.150.760', 'D13.444.735.150', 'D27.720.470.530.600.150.760'], ['B03.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Migration Pathways of Thalamic Neurons and Development of Thalamocortical Connections in Humans Revealed by Diffusion MR Tractography. | The thalamus plays an important role in signal relays in the brain, with thalamocortical (TC) neuronal pathways linked to various sensory/cognitive functions. In this study, we aimed to see fetal and postnatal development of the thalamus including neuronal migration to the thalamus and the emergence/maturation of the T... | ['Adolescent', 'Adult', 'Cell Movement', 'Child', 'Child, Preschool', 'Diffusion Magnetic Resonance Imaging', 'Diffusion Tensor Imaging', 'Humans', 'Imaging, Three-Dimensional', 'Infant', 'Infant, Newborn', 'Neural Pathways', 'Neurons', 'Thalamus', 'Young Adult'] | 27,913,428 | [['M01.060.057'], ['M01.060.116'], ['G04.198', 'G07.568.500.180'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.825.500.150'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Retroperitoneal fibrosis and inapparent obstructive uropathy. | Emphasis is placed on the minor degree of caliectasis often observed in the presence of severe renal failure in patients with retroperitoneal fibrosis. This finding should suggest the diagnosis in individuals presenting with obscure causes of renal failure. A possible explanation for this is based upon an interference ... | ['Adult', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Retroperitoneal Fibrosis', 'Ureteral Obstruction'] | 834,873 | [['M01.060.116'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['C23.550.355.700'], ['C12.777.725.776', 'C13.351.968.725.776']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Endogenous production of cytotoxic factor in mice induced by a combination of interferon-gamma and heterologous fibrinogen. | The ability of heterologous fibrinogen in combination with interferon (IFN)-gamma to induce endogenous production of cytotoxic factor was examined. Heterologous but not homologous fibrinogen induced high production of cytotoxic factor in IFN-gamma-primed mice. The cytotoxic activity was maximal 1 h after this triggerin... | ['Animals', 'Cell Line', 'Cytotoxicity, Immunologic', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Drug Synergism', 'Fibrinogen', 'Interferon-gamma', 'Killer Factors, Yeast', 'Mice', 'Mice, Inbred C3H', 'Protein Biosynthesis', 'Proteins'] | 3,108,462 | [['B01.050'], ['A11.251.210'], ['G12.287'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['G07.690.773.968.477'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.3... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fast and efficient DNA crosslinking and multiple orthogonal labelling by copper-free click chemistry. | Two new dibenzocyclooctyne-thymidine monomers were incorporated into oligonucleotides and crosslinked to azide-labelled complementary strands across the DNA grooves. Equivalent reactions were successful using a (bicyclo[6.1.0]nonyne) alkyne. Oligonucleotides containing internal cyclooctyne and amino groups were simulta... | ['Alkynes', 'Azides', 'Click Chemistry', 'Copper', 'Fluorescent Dyes', 'Nucleic Acid Conformation', 'Oligonucleotides', 'Thymidine'] | 22,892,959 | [['D02.455.326.397'], ['D01.625.100', 'D02.159'], ['E05.197.124', 'J01.897.836.249.124'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.424'], ['D03.383.742.680.705', 'D13.570.230.855', 'D13.570.685.705']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Predominance of Th2 cytokines, CXC chemokines and innate immunity mediators at the mucosal level during severe respiratory syncytial virus infection in children. | UNLABELLED: Profiling of immune mediators in both nasal and plasma samples is a common approach to the study of pathogenesis in respiratory viral infections. Nevertheless, mucosal immunity functions essentially independently from peripheral immunity. In our study, 27 immune mediators were profiled in parallel, in nasop... | ['Antibody Formation', 'Chemokines', 'Chemokines, CXC', 'Cytokines', 'Humans', 'Hydrocortisone', 'Immunity, Cellular', 'Immunity, Innate', 'Immunity, Mucosal', 'Infant', 'Intercellular Signaling Peptides and Proteins', 'Nasopharynx', 'Respiratory Mucosa', 'Respiratory Syncytial Virus Infections', 'Respiratory Syncytial... | 17,823,085 | [['G12.450.050.370.250'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374.200.120', 'D12.776.467.374.200.120', 'D23.125.300.120', 'D23.469.200.120', 'D23.529.374.200.120'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Seasonal abundance, parity, and survival of adult Culicoides sonorensis (Diptera: Ceratopogonidae) in southern Alberta, Canada. | Culicoides sonorensis (Wirth & Jones) (Diptera: Ceratopogonidae) adults were active from May through October during 2002-2006 in southern Alberta, Canada. Adults were first captured in May, and populations peaked in early June, late July, and late August. The first population peak occurred when mean weekly temperatures... | ['Alberta', 'Animals', 'Ceratopogonidae', 'Longevity', 'Population Dynamics', 'Reproduction', 'Seasons', 'Time Factors'] | 18,047,194 | [['Z01.107.567.176.064'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.500'], ['G07.345.124.519', 'G07.540'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G08.686.784'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.910.857']] | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Loa loa Microfilariae in Skin Snips: Consequences for Onchocerciasis Monitoring and Evaluation in L. loa-Endemic Areas. | The specificity of skin snips for onchocerciasis diagnoses is considered to be almost 100%. Our molecular methods revealed that microfilariae emerging from skin snips collected from highly microfilaremic Loa loa-infected individuals were largely misidentified as Onchocerca volvulus. This has important implications for ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Child', 'Female', 'Humans', 'Loa', 'Loiasis', 'Male', 'Microfilariae', 'Middle Aged', 'Onchocerca volvulus', 'Onchocerciasis', 'Young Adult'] | 30,861,060 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.500.294.400.937.463.410'], ['C01.610.335.508.700.750.361.518'], ['B01.050.500.500.294.400.937.463.470', 'B05.525'], ['M01.060.116.630'], ['B01.050... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Restricted transcription from sigma H or phosphorylated spo0A dependent promoters in the temperature-sensitive secA341 mutant of Bacillus subtilis. | The temperature-sensitive secA341 mutation of Bacillus subtilis affects sporulation and sporulation-associated events as well as protein secretion and cell septation. With lacZ or bgaB fusion genes, we examined the expression of the early sporulation genes in the mutant strain. Transcriptional expression of delta H dep... | ['Adenosine Triphosphatases', 'Bacillus subtilis', 'Bacterial Proteins', 'Escherichia coli Proteins', 'Gene Expression Regulation, Bacterial', 'Membrane Transport Proteins', 'Mutation', 'Phosphorylation', 'Promoter Regions, Genetic', 'SEC Translocation Channels', 'SecA Proteins', 'Sigma Factor', 'Temperature', 'Transcr... | 9,805,371 | [['D08.811.277.040.025'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['D12.776.097.275'], ['G05.308.300'], ['D12.776.157.530', 'D12.776.543.585'], ['G05.365.590'], ['G02.111.665', 'G02.607.780', 'G... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enhanced sensitization and elicitation responses caused by mixtures of common fragrance allergens. | BACKGROUND: Perfumes are complex mixtures composed of many fragrance ingredients, many of which are known to be only weak allergens when tested individually. It is therefore surprising that fragrance contact allergy is one of the most common forms of contact allergy.OBJECTIVES: To investigate whether mixing different f... | ['Acrolein', 'Aldehydes', 'Allergens', 'Animals', 'CD4 Lymphocyte Count', 'CD8-Positive T-Lymphocytes', 'Cell Proliferation', 'Cells, Cultured', 'Cyclohexenes', 'Dermatitis, Allergic Contact', 'Dose-Response Relationship, Immunologic', 'Eugenol', 'Female', 'Flow Cytometry', 'Mice', 'Mice, Inbred CBA', 'Perfume'] | 21,767,274 | [['D02.047.122'], ['D02.047'], ['D23.050.063'], ['B01.050'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['A11.118.637.555.567.569.220', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of inoculum and sulfide type on simultaneous hydrogen sulfide removal from biogas and nitrogen removal from swine slurry and microbial mechanism. | Four reactors were initiated to study the effect of inoculum and sulfide type on the simultaneous hydrogen sulfide removal from biogas and nitrogen removal from swine slurry (Ssu-Nir) process. Anaerobic sludge, aerobic sludge, and water were used as inocula, and Na2S and biogas were used as a sulfide substrate, respect... | ['Anaerobiosis', 'Animals', 'Biofuels', 'Biota', 'Cluster Analysis', 'DNA, Bacterial', 'DNA, Ribosomal', 'Hydrogen Sulfide', 'Molecular Sequence Data', 'Nitrogen', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Sewage', 'Swine'] | 26,286,512 | [['G02.111.062', 'G03.078'], ['B01.050'], ['D20.147', 'N06.230.132.644.124'], ['G16.500.275.157.049.100', 'N06.230.124.049.100'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308.212'], ['D13.444.308.475'], ['D01.029.260.340', 'D01.362.350', 'D01.875.350'], ['L01.453.245.667'], ['D01.268... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus. | Systemic Lupus Erythematosus (SLE) is characterized by B cells lacking IgD and CD27 (double negative; DN). We show that DN cell expansions reflected a subset of CXCR5- CD11c+ cells (DN2) representing pre-plasma cells (PC). DN2 cells predominated in African-American patients with active disease and nephritis, anti-Smith... | ['Adult', 'Aged', 'Aged, 80 and over', 'B-Lymphocyte Subsets', 'B-Lymphocytes', 'Female', 'Gene Regulatory Networks', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Plasma Cells', 'Toll-Like Receptor 7', 'Transcriptome', 'Young Adult'] | 30,314,758 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A11.063.438.450', 'A11.118.637.555.567.550.450', 'A11.118.637.555.567.562.200', 'A15.145.229.637.555.567.550.450', 'A15.145.229.637.555.567.562.200', 'A15.382.032.438.450', 'A15.382.490.555.567.550.300', 'A15.382.490.555.567.562.450'], ['A11.063.438', 'A... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acid-etch retained cast metal prostheses: a seven-year retrospective study. | The results of this study showed: retention rate was good, caries on the retainer teeth was almost nonexistent, and the supporting tissue clinically did not appear to have a greater incidence of periodontal problems. We believe that these results indicate that the cast acid-etch retained anterior prosthesis should be c... | ['Acid Etching, Dental', 'Adolescent', 'Adult', 'Aged', 'Dental Caries', 'Denture Design', 'Denture Retention', 'Denture, Partial, Fixed', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Periodontium', 'Retrospective Studies'] | 6,373,887 | [['E06.931.475.111'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C07.793.720.210'], ['E06.780.346.760.300', 'E06.912.250'], ['E06.780.346.760.550'], ['E06.780.346.760.943.271', 'E07.695.190.200.220.220'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adsorption of a phage tail-like bacteriocin to isolated lipopolysaccharide of Rhizobium. | Purified lipopolysaccharide (LPS) from the bacteriocin sensitive strain Rhizobium lupini i6-2 was shown to neutralize the killing activity of the bacteriocin. In the electron microscopical preparation the phage tail-like bacteriocin appears to be adsorbed to the LPS; the tail sheath is contracted and the fibres are ori... | ['Acetates', 'Adsorption', 'Bacteriocins', 'Deoxycholic Acid', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Lipopolysaccharides', 'Polysaccharides, Bacterial', 'Rhamnose', 'Rhizobium', 'Soil Microbiology', 'Temperature'] | 21,942 | [['D02.241.081.018', 'D10.251.400.045'], ['G01.030', 'G02.020'], ['D12.776.097.151', 'D12.776.543.695.110'], ['D04.210.500.105.225.272', 'D04.210.500.221.430.342'], ['G02.300'], ['G02.380'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['D09.698.718', 'D23.050.161.616'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Cyanotic congenital heart disease following fertility treatments in the United States from 2011 to 2014. | OBJECTIVE: To examine the risk for cyanotic congenital heart diseases (CCHDs) among live births in the USA, resulting from various forms of infertility treatments.METHODS: This study is a cross-sectional analysis of live births in the USA from 2011 to 2014. Infertility treatments are categorised into two of the followi... | ['Adult', 'Cross-Sectional Studies', 'Female', 'Heart Defects, Congenital', 'Humans', 'Infertility, Female', 'Maternal Age', 'Middle Aged', 'Pregnancy', 'Reproductive Techniques, Assisted', 'Risk Factors', 'Young Adult'] | 29,146,625 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['G08.686.560', 'N05.715.350.075.550', 'N06.850.490.250.550'], ['M01.060.116.630'], ['G08.686.784.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prognostic Factors for Nonsurgically Treated Sagittal Band Injuries of the Metacarpophalangeal Joint. | PURPOSE: The aim of this study was to evaluate the factors that influence the prognosis for patients with sagittal band injuries who were treated nonsurgically.METHODS: A total of 94 patients who had been diagnosed with traumatic sagittal band injury and initially treated with 7 weeks of metacarpophalangeal (MCP) joint... | ['Adolescent', 'Adult', 'Age Factors', 'Disability Evaluation', 'Female', 'Follow-Up Studies', 'Hand Strength', 'Humans', 'Male', 'Metacarpophalangeal Joint', 'Middle Aged', 'Occupations', 'Orthotic Devices', 'Prognosis', 'Retrospective Studies', 'Tendon Injuries', 'Treatment Failure', 'Young Adult'] | 30,660,398 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.405.500'], ['M01.060.116.630']... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Characteristics of the mitotic cycle of cells during the terminal stage of development of ascitic hepatoma 22A]. | The authors studied growth peculiarities of the ascitic hepatoma 22A at the terminal stage of development. As shown by the autoradiography method, some of the cells could be at the G1-period or at the R1-period for 2 or even 4 days; the average duration of the G2-period constituted 16 hours. 55--60% of the cells were a... | ['Animals', 'Cell Cycle', 'Liver Neoplasms, Experimental', 'Mice', 'Mice, Inbred Strains', 'Mitotic Index', 'Thymidine'] | 708,878 | [['B01.050'], ['G04.144'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['E01.370.225.500.385.500', 'E05.200.500.385.500', 'E05.242.385.500'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sources and performance criteria of uncertainty of reference measurement procedures. | OBJECTIVE: This article wants to focus on the today available Reference Measurement Procedures (RMPs) for the determination of various analytes in Laboratory Medicine and the possible tools to evaluate their performance in the laboratories who are currently using them.METHODS: A brief review on the RMPs has been perfor... | ['Calibration', 'Cholesterol', 'Clinical Laboratory Techniques', 'Databases, Factual', 'Glycated Hemoglobin A', 'Humans', 'Quality Assurance, Health Care', 'Reference Standards', 'Uncertainty'] | 29,856,964 | [['E05.978.155'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E01.370.225', 'E05.200'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Fatal diphenidol poisoning: a case report and a retrospective study of 16 cases. | Diphenidol hydrochloride (DPN), a nonphenothiazinic antiemetic agent used primarily in patients with Meniere disease and labyrinthopathies to treat vomiting and vertigo, is considered to be a relatively safe drug. Since it was first approved in the United States in 1967, this drug has been widely used in Latin America ... | ['Antiemetics', 'Brain Edema', 'Female', 'Gastrointestinal Contents', 'Humans', 'Liver', 'Molecular Structure', 'Piperidines', 'Retrospective Studies', 'Suicide', 'Young Adult'] | 26,481,789 | [['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['C10.228.140.187'], ['A12.519'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['G02.111.570', 'G02.466'], ['D03.383.621'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Incidentalomas of the adrenal gland: diagnostic and therapeutic implications. | Incidentally discovered adrenal masses are common since the advent and application of sensitive noninvasive imaging methods. The significance of these so-called "incidentalomas" and the question of further evaluation or treatment remains elusive. This report describes a retrospective study of 86 patients with incidenta... | ['Adrenal Gland Neoplasms', 'Adrenalectomy', 'Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies'] | 9,124,759 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['E04.270.115'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.5... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4â-S-aromatic heterocyclic podophyllum derivatives display antitumor activity. | Herein is a first effort to systematically study the significance of carbon-sulfur (C-S) and carbon-amine (C-NH) bonds on the antitumor proliferation activity of podophyllum derivatives and their precise mechanism of apoptosis. Compared with the derivative modified by a C-NH bond, the derivative modified by a C-S bond ... | ['Amines', 'Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Biological Transport', 'Carbon', 'Cell Cycle', 'Cell Line', 'Cell Line, Tumor', 'DNA Topoisomerases, Type II', 'Dose-Response Relationship, Drug', 'HeLa Cells', 'Hepatocytes', 'Humans', 'Microtubules', 'Mitochondria', 'Plant Extracts', 'Podophyllotoxin', 'Po... | 26,443,888 | [['D02.092'], ['D27.505.954.248.179'], ['G04.146.954.035'], ['G03.143'], ['D01.268.150'], ['G04.144'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.811.399.403.741'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['A11.436.348'], ['B01.050.150.9... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phylogenetic supermatrix analysis of GenBank sequences from 2228 papilionoid legumes. | A comprehensive phylogeny of papilionoid legumes was inferred from sequences of 2228 taxa in GenBank release 147. A semiautomated analysis pipeline was constructed to download, parse, assemble, align, combine, and build trees from a pool of 11,881 sequences. Initial steps included all-against-all BLAST similarity searc... | ['Algorithms', 'Base Sequence', 'Cluster Analysis', 'Computational Biology', 'Databases, Nucleic Acid', 'Fabaceae', 'Molecular Sequence Data', 'Phylogeny', 'Plant Proteins', 'Sequence Alignment', 'Sequence Analysis, DNA'] | 17,060,202 | [['G17.035', 'L01.224.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.300.500', 'L01.313.500.750.300.188.400.325.630', 'L01.470.750.750.300.500', 'L01.470.750.750.325.63... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Nonlinearities in stereoscopic phase-differencing. | Exploiting the quasi-linear relationship between local phase and disparity, phase-differencing registration algorithms provide a fast, powerful means for disparity estimation. Unfortunately, these phase-differencing techniques suffer a significant impediment: phase nonlinearities. In regions of phase nonlinearity, the ... | ['Algorithms', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Microscopy, Phase-Contrast', 'Nonlinear Dynamics', 'Photogrammetry', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 18,713,673 | [['G17.035', 'L01.224.050'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.515.513.569', 'E05.490.630.569', 'E05.595.513.569'], ['E05.599.850', 'H01.548.675'], ['E01.370.350.600.630'], ['E05.318.370.72... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[A highly sensitive assay method of oxalic acid in human plasma using high performance liquid chromatography with fluorescent labeling reagent]. | An assay method for the plasma level of oxalic acid (OA) was developed by using high-performance liquid chromatography (HPLC). Low molecular weight carboxylic acids including OA were separated from interfering plasma components by passing through ultrafilter (Centriflow CF 25, Amicon) and a Sep-Pak C18 cartridge (Water... | ['Anthracenes', 'Chromatography, High Pressure Liquid', 'Fluorescent Dyes', 'Humans', 'Oxalates', 'Oxalic Acid'] | 2,754,617 | [['D02.455.426.559.847.117', 'D04.615.117'], ['E05.196.181.400.300'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.081.337.593'], ['D02.241.081.337.593.750']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification and characterization of wheat drought-responsive MYB transcription factors involved in the regulation of cuticle biosynthesis. | A plant cuticle forms a hydrophobic layer covering plant organs, and plays an important role in plant development and protection from environmental stresses. We examined epicuticular structure, composition, and a MYB-based regulatory network in two Australian wheat cultivars, RAC875 and Kukri, with contrasting cuticle ... | ['Dehydration', 'Gene Expression Regulation, Plant', 'Microscopy, Electron, Scanning', 'Plant Leaves', 'Plant Proteins', 'Transcription Factors', 'Triticum', 'Waxes'] | 27,489,236 | [['C18.452.950.179', 'C23.550.274'], ['G05.308.375'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A18.024.812'], ['D12.776.765'], ['D12.776.930'], ['B01.650.940.800.575.912.250.822.918'], ['D10.945']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photodynamic inactivation of gramicidin channels:a flash-photolysis study. | Photosensitized inactivation of ionic channels formed by gramicidin in the planar bilayer lipid membrane (BLM) has been studied upon exposure of the BLM to single flashes of visible light in the presence of tetrasulphonated aluminium phthalocyanine. The gramicidin photoinactivation is inhibited by the addition of unsat... | ['Gramicidin', 'Indoles', 'Ion Channels', 'Lipid Bilayers', 'Membranes, Artificial', 'Photolysis'] | 8,695,636 | [['D04.345.566.850.300', 'D12.644.641.850.300', 'D12.776.543.695.221'], ['D03.633.100.473'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D10.570.510', 'J01.637.087.500.510'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G02.740.685']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Occlusal loading evaluation in the cervical integrity of Class II cavities filled with composite. | There are many doubts about the clinical behavior of condensable composite restorations in Class II cavities, particularly when they are submitted to axial mechanical loads. This study evaluated cervical microleakage in Class II direct fillings in composite, whether or not they were submitted to an occlusal load cyclin... | ['Acid Etching, Dental', 'Bite Force', 'Coloring Agents', 'Composite Resins', 'Dental Cavity Preparation', 'Dental Cements', 'Dental Enamel', 'Dental Leakage', 'Dental Restoration, Permanent', 'Dentin', 'Dentin-Bonding Agents', 'Humans', 'Materials Testing', 'Polymethacrylic Acids', 'Stress, Mechanical', 'Tooth Cervix'... | 16,382,595 | [['E06.931.475.111'], ['E06.276.125'], ['D27.720.233'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.931.325'], ['D25.339.291', 'J01.637.051.339.291'], ['A14.549.167.900.255'], ['C07.793.221'], ['E06.323.428', 'E06.780.346.737', 'E07.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Hydrophilic, semipermeable membranes fabricated with poly(ethylene oxide)-polysulfone block copolymer. | Semipermeable membranes may be fabricated from mixtures of poly(ethylene oxide)/polysulfone block copolymer (PEO-b-PSF) and polysulfone. Membranes fabricated with PEO-b-PSF possess a hydrophilic surface. PEO-b-PSF segregates to the membrane surface during phase inversion fabrication of the membrane rendering the surfac... | ['Animals', 'Blood Platelets', 'Cell Adhesion', 'Magnetic Resonance Spectroscopy', 'Membranes, Artificial', 'Polyethylene Glycols', 'Sulfones', 'Surface Properties', 'Swine'] | 10,711,969 | [['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['G04.022'], ['E05.196.867.519'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D02.886.590'], ['G02.860'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Central nervous system blast crisis of chronic myeloid leukaemia misdiagnosed as tubercular meningitis. | Chronic Myeloid Leukaemia (CML) presenting with isolated Central Nervous System (CNS) blast crisis is an uncommon entity. A 22-year-old man, diagnosed with chronic phase CML in 2011 and was in haematological and cytogenetic remission until July 2016, had acute onset headache and vomiting with meningeal signs and was ad... | ['Adult', 'Antitubercular Agents', 'Blast Crisis', 'Central Nervous System', 'Diagnostic Errors', 'Drug Therapy', 'Fever', 'Granulocyte Precursor Cells', 'Headache', 'Humans', 'Injections, Spinal', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Rare Diseases', 'Treatment Outcome', 'Tuberculosis, Meningeal... | 29,895,576 | [['M01.060.116'], ['D27.505.954.122.085.255'], ['C04.557.337.539.250.100', 'C04.697.098.500.110', 'C15.378.190.636.370.100', 'C23.550.727.098.500.110'], ['A08.186'], ['E01.354', 'N02.421.450.280'], ['E02.319'], ['C23.888.119.344'], ['A11.148.350.350', 'A11.148.378.590.675.500', 'A11.627.340.360', 'A11.627.635.675.500',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
On the enzymatic activation of NADH. | Atomic (1 A) resolution x-ray structures of horse liver alcohol dehydrogenase in complex with NADH revealed the formation of an adduct in the active site between a metal-bound water and NADH. Furthermore, a pronounced distortion of the pyridine ring of NADH was observed. A series of quantum chemical calculations on the... | ['Alcohol Dehydrogenase', 'Animals', 'Binding Sites', 'Crystallography, X-Ray', 'Electron Probe Microanalysis', 'Horses', 'Liver', 'Models, Molecular', 'NAD'] | 11,134,046 | [['D08.811.682.047.820.250'], ['B01.050'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['B01.050.150.900.649.313.984.235.472'], ['A03.620'], ['E05.599.595'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intrauterine gastric perforation. | We describe a case of intrauterine gastric perforation in a 31-week gestational age baby girl. The patient presented at birth with abdominal distension, respiratory distress, and massive pneumoperitoneum on radiography. The perforation was managed by resuscitation, celiotomy, and gastrostomy tube placement through the ... | ['Diagnosis, Differential', 'Female', 'Fetal Diseases', 'Gastrostomy', 'Humans', 'Infant, Newborn', 'Pregnancy', 'Prenatal Diagnosis', 'Rupture, Spontaneous', 'Stomach Rupture'] | 16,807,718 | [['E01.171'], ['C13.703.277', 'C16.300'], ['E04.210.496', 'E04.579.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769'], ['E01.370.378.630'], ['C23.300.909'], ['C06.405.748.824', 'C26.017.809', 'C26.761.684']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of the dissolution behaviour of tablets containing the drug in a polyethyleneglycol solid dispersion with direct compressed tablets. | Higher dissolution rates of diazepam were noted with tablets containing the drug in polyethyleneglycol solid dispersion compared to these containing a physical mixture of the drug granulated with polyethyleneglycol or to directly compressed tablets. The shape factor and t63% depend strongly on the method of incorporati... | ['Chemistry, Pharmaceutical', 'Drug Compounding', 'Polyethylene Glycols', 'Solubility', 'Tablets'] | 2,726,990 | [['H01.158.703.007', 'H01.181.466'], ['E05.916.270'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['G02.805'], ['D26.255.830']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Results of one-stage reconstruction of anal sphincter in surgical treatment of fistulas-in-ano combined with fecal incontinence]. | The investigation included 20 patients. Mean index of the severity of incontinence before operation by the Wexner scale was 9.3+/-2.4 scores. After radical dissection of the fistula and sphincter plasty in 7 patients (the first group) the wound of the rectum mucosa was sutured in longitudinal direction, in 13 patients ... | ['Adult', 'Anal Canal', 'Antibiotic Prophylaxis', 'Ceftriaxone', 'Fecal Incontinence', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Manometry', 'Metronidazole', 'Middle Aged', 'Perioperative Care', 'Proctoscopy', 'Recovery of Function', 'Rectal Fistula', 'Recurrence', 'Severity of Illness Index', 'Surgical Flaps',... | 21,848,239 | [['M01.060.116'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['E02.319.162.150', 'E02.319.703.150'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['C06.405.469.860.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.35... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Nephrogenic diabetes insipidus in a large family]. | Hereditary nephrogenic diabetes insipidus is a rare disease. We describe here three brothers with this disease from a big family consisting of 10 siblings. The case is undoubtedly X-linked because the sufferers are only boys, one of them with a different father. The illness was noticed rather late, namely, at the ages ... | ['Adolescent', 'Child', 'Child, Preschool', 'Chromosomes, Human, X', 'Diabetes Insipidus, Nephrogenic', 'Diuretics', 'Humans', 'Hydrochlorothiazide', 'Male', 'Mutation', 'Pedigree', 'Sex Factors', 'Time Factors'] | 16,528,130 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['C12.777.419.135.500', 'C13.351.968.419.135.500'], ['D27.505.696.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.590.700.13... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The organizational aspects of medical support of convicts in the Republic of Sakha (Yakutia)]. | The organization of medical care in the Central hospital of the department of Federal penitentiary service of Russia of the Republic of Sakha (Yakutia) was examined The analysis of morbidity of convicts was carried out. The activities concerning enhancement of quality of organization of medical care considering tendenc... | ['Criminals', 'Delivery of Health Care', 'Humans', 'Russia'] | 26,012,275 | [['M01.142'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prevalence and correlates of snoring and observed apneas in 5,201 older adults. | The objectives of this study were to describe the prevalence of snoring, observed apneas, and daytime sleepiness in older men and women, and to describe the relationships of these sleep disturbances to health status and cardiovascular diseases (CVD). A cross-sectional design was employed to study sleep problems, CVD, g... | ['Activities of Daily Living', 'Age Factors', 'Aged', 'Cardiovascular Diseases', 'Comorbidity', 'Female', 'Humans', 'Incidence', 'Lung Diseases', 'Male', 'Narcolepsy', 'Prevalence', 'Random Allocation', 'Sex Factors', 'Sleep Apnea Syndromes', 'Snoring'] | 8,899,931 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C14'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Membrane permeability of secondary hydatid cysts of Echinococcus granulosus. Determination of the water diffusional and osmotic permeability coefficients through a syncytial membrane. | Diffusional (Pw) and osmotic (Pf) water permeability coefficients were determined for the syncytial epithelium of larval Echinococcus granulosus. Pw was calculated from simultaneous influx measurements of tritiated water and n-[14C]butanol through the hydatid cyst wall. The total diffusional water permeability coeffici... | ['Animals', 'Ascitic Fluid', 'Cell Membrane Permeability', 'Diffusion', 'Echinococcosis', 'Echinococcus', 'Larva', 'Mice', 'Models, Biological', 'Osmosis', 'Raffinose', 'Sucrose', 'Water'] | 6,749,186 | [['B01.050'], ['A12.207.119'], ['G03.143.335', 'G04.175'], ['G01.202', 'G02.196'], ['C01.610.335.190.396'], ['B01.050.500.500.736.215.327'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['D09.698.6... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphological features of Acanthamoeba causing keratitis contaminated from contact lens cases. | OBJECTIVE: To study the morphological characteristics of genus Acanthamoeba which is an opportunistic organism associated with wearing contact lenses that the biofilm phenomenon in contact lens cases contained Acanthamoeba causing keratitis by conventional culture technique.MATERIAL AND METHOD: A total of 150 contact l... | ['Acanthamoeba', 'Acanthamoeba Keratitis', 'Amebiasis', 'Biofilms', 'Contact Lens Solutions', 'Contact Lenses', 'Humans', 'Microscopy, Atomic Force', 'Pilot Projects', 'Prevalence', 'Pseudopodia', 'Thailand', 'Trophozoites'] | 20,235,365 | [['B01.046.500.100.075.080'], ['C01.610.300.125', 'C01.610.752.049.203', 'C11.204.564.112', 'C11.294.725.125'], ['C01.610.752.049'], ['A20.593', 'G06.120'], ['D26.776.210', 'D27.505.954.122.425.150', 'D27.720.274.150'], ['E07.632.500.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.666.400', 'E... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Variable effects of soy protein on plasma lipids in hyperlipidemic and normolipidemic hemodialysis patients. | BACKGROUND: Hyperlipidemic factors contribute to the high cardiovascular risk in hemodialysis patients. Soy protein has decreased some atherogenic lipid concentrations in subjects with normal renal function. This study evaluates the effect of soy protein on serum lipid profiles in hyperlipidemic and normolipidemic hemo... | ['Aged', 'Apolipoproteins B', 'Body Mass Index', 'Cholesterol', 'Dietary Proteins', 'Double-Blind Method', 'Female', 'Humans', 'Hyperlipidemias', 'Insulin', 'Kidney Failure, Chronic', 'Lipoproteins, HDL', 'Lipoproteins, LDL', 'Male', 'Middle Aged', 'Milk Proteins', 'Renal Dialysis', 'Soybean Proteins', 'Treatment Outco... | 16,310,576 | [['M01.060.116.100'], ['D10.532.091.300', 'D12.776.070.400.300', 'D12.776.521.120.300'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['E05.318.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Plasma calcium and calcitonin levels in eels fed a high calcium solution or transferred to seawater. | To examine the physiological role of calcitonin (CT) in calcium homeostasis of teleosts, we compared calcium and CT levels in freshwater eels fed a high calcium-consomme solution (Ca2+: 1.25 M; 1 ml/100 g body wt) into the stomach (Experiment I), and in freshwater eels transferred from freshwater to seawater (Experimen... | ['Adaptation, Physiological', 'Anguilla', 'Animals', 'Calcitonin', 'Calcium', 'Calcium, Dietary', 'Fresh Water', 'Homeostasis', 'Seawater', 'Solutions'] | 10,336,820 | [['G07.025', 'G16.012.500'], ['B01.050.150.900.493.338.282'], ['B01.050'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.146.395'], ['G16.500.275.280', 'N06.230.232'], ['G07.410'], ['G16.500.275.725.500']... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Biochemical alterations in the trapezius muscle of patients with chronic whiplash associated disorders (WAD)--a microdialysis study. | The mechanisms behind the development of chronic trapezius myalgia in patients with whiplash associated disorders (WAD) appear to involve both peripheral and central components, but the specific contribution of alterations in muscle is not clear. Female patients with WAD and involvement of trapezius (N=22) and female c... | ['Adult', 'Chronic Disease', 'Exercise', 'Female', 'Glutamic Acid', 'Humans', 'Interleukin-6', 'Lactic Acid', 'Microdialysis', 'Middle Aged', 'Muscle, Skeletal', 'Neck Pain', 'Pain Measurement', 'Pain Threshold', 'Potassium', 'Pressure', 'Pyruvic Acid', 'Regional Blood Flow', 'Serotonin', 'Shoulder', 'Whiplash Injuries... | 17,459,742 | [['M01.060.116'], ['C23.550.291.500'], ['G11.427.410.698.277', 'I03.350'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D02.241.511.459.450'], ['E05.196.353.500'], ['M0... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Hemispheric asymmetry and visuo-olfactory integration in perceiving subthreshold (micro) fearful expressions. | Multisensory integration is ubiquitous, facilitating perception beyond the limit of individual senses. This mechanism is especially salient when individual sensory input is weak (i.e., the principle of inverse effectiveness), fusing subthreshold cues into tangible percepts. Nevertheless, it is unclear how this rule app... | ['Facial Expression', 'Fear', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Odorants', 'Photic Stimulation', 'Reaction Time', 'Smell', 'Visual Perception', 'Young Adult'] | 22,323,728 | [['E01.370.600.225', 'F01.145.209.530.385'], ['F01.470.361'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.275.640', 'N06.230.480'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.830.816.643', 'G11.561.790.643'], ['F02.463.593.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular Engineering of Acoustic Protein Nanostructures. | Ultrasound is among the most widely used biomedical imaging modalities, but has limited ability to image specific molecular targets due to the lack of suitable nanoscale contrast agents. Gas vesicles-genetically encoded protein nanostructures isolated from buoyant photosynthetic microbes-have recently been identified a... | ['Acoustics', 'Contrast Media', 'Microbubbles', 'Nanostructures', 'Proteins', 'Ultrasonography'] | 27,351,374 | [['H01.671.031'], ['D27.505.259.500', 'D27.720.259'], ['E07.553'], ['J01.637.512'], ['D12.776'], ['E01.370.350.850']] | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Membrane sequestration by the EIIB domain of the mannitol permease MtlA activates the Bacillus subtilis mtl operon regulator MtlR. | In most firmicutes expression of the mannitol operon is regulated by MtlR. This transcription activator is controlled via phosphorylation of its regulatory domains by components of the phosphoenolpyruvate : carbohydrate phosphotransferase system (PTS). We found that activation of Bacillus subtilis MtlR also requires an... | ['Bacillus subtilis', 'Bacterial Proteins', 'Cell Membrane', 'Gene Expression Regulation, Bacterial', 'Mannitol', 'Membrane Transport Proteins', 'Operon', 'Protein Binding', 'Protein Structure, Tertiary', 'Repressor Proteins'] | 23,279,188 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['A11.284.149'], ['G05.308.300'], ['D02.033.800.609', 'D09.853.609'], ['D12.776.157.530', 'D12.776.543.585'], ['G05.360.340.024.686', 'G05.360.340.358.20... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pacing in Olympic track races: competitive tactics versus best performance strategy. | The purpose of this study was to describe pacing strategies in the 800 to 10,000-m Olympic finals. We asked 1) if Olympic finals differed from World Records, 2) how variable the pace was, 3) whether runners faced catastrophic events, and 4) for the winning strategy. Publically available data from the Beijing 2008 Olymp... | ['Athletic Performance', 'Competitive Behavior', 'Decision Making', 'Female', 'Humans', 'Male', 'Running'] | 22,738,897 | [['I03.450.642.845.054'], ['F01.145.813.105'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[Pharmacokinetics of meloxicam in healthy Chinese volunteers]. | AIM: To assess the pharmacokinetic profile of single doses of meloxicam in healthy Chinese volunteers.METHODS: The plasma concentrations of meloxicam after an oral dose of 15 mg to twenty healthy male volunteers were analyzed by means of a validated HPLC method. The pharmacokinetic parameters were subjected to Shapiro-... | ['Adult', 'Anti-Inflammatory Agents, Non-Steroidal', 'Area Under Curve', 'Humans', 'Male', 'Meloxicam', 'Thiazines', 'Thiazoles'] | 12,579,866 | [['M01.060.116'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.665.275', 'D02.886.675.448', 'D03.383.129.708.448', 'D03.383.855.275'], ['D02.886.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Histopathologic changes in the brain, heart, and skeletal muscle of rhesus macaques, ten days after exposure to soman (an organophosphorus nerve agent). | BACKGROUND AND PURPOSE: Soman, an organophosphorus, anticholinergic, chemical warfare nerve agent, is studied at few research facilities, and there have been few pathologic studies of soman-exposed primates. We describe the brain, heart, and skeletal muscle lesions, review lesions described in literature, and discuss p... | ['Animals', 'Anticonvulsants', 'Astrocytes', 'Brain', 'Chemical Warfare Agents', 'Cholinesterase Inhibitors', 'Dose-Response Relationship, Drug', 'Glial Fibrillary Acidic Protein', 'Gliosis', 'Heart', 'Hippocampus', 'Macaca mulatta', 'Male', 'Muscle, Skeletal', 'Myocardium', 'Neurons', 'Organophosphorus Compounds', 'Se... | 10,857,003 | [['B01.050'], ['D27.505.954.427.080'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['D27.720.777.300', 'D27.888.569.612.150', 'J01.637.870.900.200'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['G07.690.773.875', 'G07.690.936.500'], ['D05.750.078.593.400', 'D12.776.220.475.400']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Investigation of an outbreak of Salmonella typhi in a public school in Madrid. | A typhoid fever outbreak affecting 54 school students occurred in a Public School of M?stoles, Madrid. The date of onset was 11 June 1991 and the last detected case was 8 July 1991. Salmonella typhi was cultured from blood and/or stool samples corresponding to 54 patients and one food-handler. There were no secondary c... | ['Adolescent', 'Amoxicillin', 'Ampicillin', 'Bacterial Typing Techniques', 'Carrier State', 'Child', 'Disease Outbreaks', 'Feces', 'Female', 'Food Handling', 'Food Microbiology', 'Humans', 'Incidence', 'Male', 'Microbial Sensitivity Tests', 'Oxidoreductases', 'Plasmids', 'Population Surveillance', 'Recurrence', 'Salmon... | 8,405,309 | [['M01.060.057'], ['D02.065.589.099.750.750.050.050', 'D02.886.108.750.750.050.050', 'D03.633.100.300.750.750.050.050'], ['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['N06.850.520.169'], ['M01.060.406'], ['N06.850.290'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Educati... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Interferon-gamma-dependent inhibition of late allergic airway responses and eosinophilia by CD8+ gammadelta T cells. | We have previously shown that CD8(+)gammadelta T cells decrease late allergic airway responses, airway eosinophilia, T helper 2 cytokine expression and increase interferon-gamma (IFN-gamma) expression. We hypothesized that the effects of CD8(+)gammadelta T cells were IFN-gamma mediated. Brown Norway rats were sensitize... | ['Adoptive Transfer', 'Animals', 'Antigens', 'Asthma', 'Bronchoalveolar Lavage Fluid', 'CD8-Positive T-Lymphocytes', 'Cysteine', 'Eosinophil Major Basic Protein', 'Eosinophilia', 'Gene Expression Regulation', 'Interferon-gamma', 'Interleukin-4', 'Leukotrienes', 'Macrophages, Alveolar', 'Male', 'Oligodeoxyribonucleotide... | 17,848,163 | [['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['D23.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.927.100.500'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D02.886.030.230', 'D02.886.489.155', 'D12... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcutaneous electrical tibial nerve stimulation in the treatment of fecal incontinence: a randomized trial (CONSORT 1a). | OBJECTIVES: The objective of this study was to show that although transcutaneous electrical tibial nerve stimulation (TENS) is being increasingly used to treat fecal incontinence (FI), its efficacy has never been proved using controlled trials.METHODS: In this randomized, double-blind, sham-controlled trial, 144 patien... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anal Canal', 'Defecation', 'Double-Blind Method', 'Fecal Incontinence', 'Female', 'Humans', 'Male', 'Manometry', 'Middle Aged', 'Quality of Life', 'Rectum', 'Self Report', 'Severity of Illness Index', 'Surveys and Questionnaires', 'Tibial Nerve', 'Time Factors', 'Transcutaneous E... | 23,032,981 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['G10.261.165'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['M01.060.116.630'... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Action of beta-galactosidase on novel synthetic macromolecular substrates. A processive enzymic reaction controlled by coulombic interactions. | Macromolecular beta-galactosidase substrates were prepared by attaching o-nitrophenyl-beta-galactoside to carboxymethyldextran with positively charged linking groups. Almost all of the substituents were susceptible to enzymic hydrolysis by two distinct pathways. Under some conditions, there was random reaction to give ... | ['Dextrans', 'Galactosidases', 'Hydrolysis', 'Kinetics', 'Macromolecular Substances', 'Molecular Weight', 'Nitrophenylgalactosides', 'beta-Galactosidase'] | 2,410,029 | [['D05.750.078.562.272', 'D09.698.365.272'], ['D08.811.277.450.410'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['D05'], ['G02.494'], ['D09.408.320.550'], ['D08.811.277.450.410.100']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of interleukin-5- and granulocyte macrophage-colony-stimulating factor-responsive genes in blood and airway eosinophils. | Because interleukin (IL)-5 family cytokines are critical regulators of eosinophil development, recruitment, and activation, this study was initiated to identify proteins induced by these cytokines in eosinophils. Using oligonucleotide microarrays, numerous transcripts were identified as responsive to both IL-5 and gran... | ['Biomarkers', 'Bronchoalveolar Lavage Fluid', 'Cells, Cultured', 'Eosinophils', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Humans', 'Interleukin-5', 'Molecular Sequence Data', 'Oligonucleotide Array Sequence Analysis', 'Respiratory System'] | 14,630,612 | [['D23.101'], ['E05.927.100.500'], ['A11.251'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['E05.393.332'], ['G05.308'], ['D12.644.276.374.410.240.375', 'D12.776.395.240.300', 'D12.776.467.374.410.240.375', 'D23.529.374.410.240.375'], ['B01.050.150.900.649.313.988.400.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[DNA from cells infected with herpes simplex virus and from human tumors as an inducer of synthesis of a new nonvirion antigen]. | DNA from herpes simplex virus type II (HSV-II)-infected cells isolated by using SDS, phenol, and pronase as well as by a new method of Pignatti et al. from triton X-100-NaCl-supernatant was shown to be capable to induce production of an early nonvirion (new) antigen in sensitive systems of Vero, RS-537 cells and others... | ['Antigens', 'Cell Line', 'DNA, Neoplasm', 'DNA, Viral', 'Female', 'Humans', 'In Vitro Techniques', 'Ovarian Neoplasms', 'Simplexvirus', 'Transfection', 'Uterine Cervical Neoplasms', 'Virus Replication'] | 6,254,273 | [['D23.050'], ['A11.251.210'], ['D13.444.308.425'], ['D13.444.308.568'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['B04.280.382.100.750'], ['E05.393.350.810', 'G05.728.860'], ['C04.588.945.418.9... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of niflumic acid on electromechanical coupling by tachykinin NK1 receptor activation in rabbit colon. | We have investigated the effect of the Cl- channel blocker, niflumic acid, on the contractile response and electromechanical coupling activated by stimulation of the tachykinin NK1 receptor in the longitudinal muscle of rabbit proximal colon, in the presence of indomethacin (5 microM). The application of submaximal equ... | ['Animals', 'Chloride Channels', 'Colon', 'In Vitro Techniques', 'Male', 'Muscle Contraction', 'Nifedipine', 'Niflumic Acid', 'Rabbits', 'Receptors, Neurokinin-1'] | 8,813,568 | [['B01.050'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['E05.481'], ['G11.427.494'], ['D03.383.725.203.540'], ['D02.241.223.100.050.400.200.777', 'D02.455.426.559.389.127.020.906.750.777', 'D03.066.515.550', 'D03.383.725.547.550']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predicting death and lost to follow-up among adults initiating antiretroviral therapy in resource-limited settings: Derivation and external validation of a risk score in Haiti. | BACKGROUND: Over 18 million adults have initiated life-saving antiretroviral therapy (ART) in resource-poor settings; however, mortality and lost-to-follow-up rates continue to be high among patients in their first year after treatment start. Clinical decision tools are needed to identify patients at high risk for poor... | ['Adolescent', 'Adult', 'Aged', 'Anti-HIV Agents', 'Antiretroviral Therapy, Highly Active', 'Developing Countries', 'Drug Utilization', 'Female', 'HIV Infections', 'Haiti', 'Humans', 'Male', 'Middle Aged'] | 30,157,197 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.388.077.088'], ['E02.319.310.075'], ['I01.615.500.300'], ['N04.452.706.477'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['Z01.107.084.900.425', 'Z01.639.880.425'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Development of airborne oil thickness measurements. | A laboratory sensor has now been developed to measure the absolute thickness of oil on water slicks. This prototype oil slick thickness measurement system is known as the laser-ultrasonic remote sensing of oil thickness (LURSOT) sensor. This laser opto-acoustic sensor is the initial step in the ultimate goal of providi... | ['Air Pollutants', 'Environmental Monitoring', 'Lasers', 'Optics and Photonics', 'Petroleum', 'Ultrasonics', 'Water Pollutants'] | 12,899,892 | [['D27.888.284.101'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E07.632.490', 'E07.710.520'], ['H01.671.617', 'J01.293.688'], ['D20.345.630', 'N06.230.132.258.630'], ['H01.671.031.849'], ['D27.888.284.903']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Compliance and efficacy of standard antenatal care model]. | OBJECTIVE: To investigate the compliance of standard antenatal care (ANC) model with 12-13 visits currently used in Beijing region, and to assess the efficacy of this model in reducing adverse maternal and perinatal complication.METHODS: The clinical data of 544 women who delivered at Peking Union Medical College Hospi... | ['Adolescent', 'Adult', 'China', 'Educational Status', 'Female', 'Humans', 'Infant, Newborn', 'Patient Compliance', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Prenatal Care', 'Retrospective Studies', 'Risk Factors'] | 16,447,646 | [['M01.060.057'], ['M01.060.116'], ['Z01.252.474.164'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['G08.686.784.769'], ['C13.703'], ['E01.789.700', 'G08.686.784.769.496'], ['E02.760.786', 'N02... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Detoxification of genotoxic compounds as a threshold mechanism limiting their carcinogenicity. | In vitro metabolic trends were assessed for 100 genotoxic agents detected in two bacterial test systems, i.e., the Ames reversion test and a liquid DNA-repair test in Escherichia coli. Seventy-five compounds were found to undergo a more or less pronounced decrease of genotoxicity, in at least one of these models, in th... | ['Aflatoxin B1', 'Aflatoxins', 'Animals', 'Biotransformation', 'Carcinogens', 'DNA Repair', 'Glutathione', 'In Vitro Techniques', 'Inactivation, Metabolic', 'Liver', 'Mutagenicity Tests', 'Mutagens', 'Neoplasms, Experimental', 'Polychlorinated Biphenyls', 'Rats', 'Salmonella typhimurium'] | 6,442,795 | [['D03.383.663.283.119.075', 'D03.633.100.150.119.075', 'D23.946.587.142.075'], ['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D27.888.569.100'], ['G02.111.222', 'G05.219'], ['D12.644.456.448'], ['E05.481'], ['G03.171.450', 'G03.787.225.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A case of advanced esophageal cancer with no recurrence treated biweekly with postoperative docetaxel/nedaplatin combined chemotherapy after non-curative surgery]. | We report a case of non-curatively resected esophageal cancer with no recurrence biweekly treated with postoperative docetaxel/nedaplatin combined chemotherapy. A 59-year-old woman underwent non-curative resection with esophagectomy for advanced esophageal cancer with direct invasion to the descending aorta in August, ... | ['Antineoplastic Combined Chemotherapy Protocols', 'Combined Modality Therapy', 'Docetaxel', 'Esophageal Neoplasms', 'Female', 'Humans', 'Neoplasm Staging', 'Organoplatinum Compounds', 'Remission Induction', 'Taxoids'] | 20,567,116 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.625'], ['D02.691.788'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
End-of-life expenditures by Ohio Medicaid beneficiaries dying of cancer. | We evaluate the extent to which the Ohio Medicaid Program serves as a safety net to terminally ill cancer patients, and the costs associated with providing care to this patient population. Over a 10-year period, Ohio Medicaid served nearly 45,000 beneficiaries dying of cancer, and spent more than $1 billion in medical ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Cohort Studies', 'Female', 'Health Expenditures', 'Humans', 'Infant', 'Male', 'Medicaid', 'Middle Aged', 'Neoplasms', 'Ohio', 'Retrospective Studies', 'Terminal Care'] | 17,427,846 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['N03.219.521.346.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Total serum alkaline phosphatase (SAP) and serum cholesterol in relation to secretor status and blood groups in myocardial infarction patients. | The relation of total serum alkaline phosphatase and serum cholesterol in convalescing patients of myocardial infarction with secretor status and blood groups have been studied. Serum cholesterol and alkaline phosphatase levels showed significant difference in secretors (98) and nonsecretors (56) in myocardial groups. ... | ['Alkaline Phosphatase', 'Blood Group Antigens', 'Cholesterol', 'Female', 'Humans', 'Male', 'Myocardial Infarction'] | 2,744,802 | [['D08.811.277.352.650.035'], ['D23.050.301.290', 'D23.050.705.230'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular analysis of oral and respiratory bacterial species associated with ventilator-associated pneumonia. | Trauma intensive care unit (TICU) patients requiring mechanical respiratory support frequently develop ventilator-associated pneumonia (VAP). Oral and oropharyngeal bacteria are believed to be responsible for many cases of VAP, but definitive evidence of this relationship is lacking. Earlier studies used conventional c... | ['Adult', 'Bacteria', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mouth', 'Phylogeny', 'Pneumonia, Bacterial', 'Pneumonia, Ventilator-Associated', 'Respiratory System', 'Species Specificity', 'Wounds and Injuries'] | 17,301,280 | [['M01.060.116'], ['B03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['C01.150.252.620', 'C01.748.610.540', 'C08.381.677.540', 'C08.730.610.540'], ['C01.248.250.500', 'C01.748.610.300.500', 'C08.381.677... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Effect of the inhibition of protein synthesis on the Escherichia coli cell envelope. | The consequences for cell envelope integrity of Escherichia coli K-12 of the inhibition of protein synthesis by a variety of means have been examined. Protein synthesis was blocked by the antibiotics chloramphenicol and streptomycin, by amino acid starvation of an amino acid auxotroph, and by inactivation of temperatur... | ['Bacterial Outer Membrane Proteins', 'Cell Membrane Permeability', 'Escherichia coli', 'Microscopy, Electron, Scanning', 'Protein Synthesis Inhibitors'] | 15,828,194 | [['D12.776.097.120', 'D12.776.543.100'], ['G03.143.335', 'G04.175'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D27.505.519.389.760']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrophysiological effects of phencyclidine and the sigma agonist ditolylguanidine in the cerebellum of the rat. | The electrophysiological actions of phencyclidine (PCP) and the sigma agonist 1,3-di(2tolyl)guanidine (DTG) were examined in the cerebellum of urethane-anesthetized rats. The object of the study was to determine if PCP and sigma agonists shared a common mechanism of action. The cerebellar Purkinje neuron was chosen bec... | ['Animals', 'Cerebellum', 'Electrophysiology', 'Guanidines', 'Haloperidol', 'Male', 'Norepinephrine', 'Oxidopamine', 'Phencyclidine', 'Purkinje Fibers', 'Rats', 'Rats, Inbred Strains', 'Synaptic Transmission'] | 1,311,809 | [['B01.050'], ['A08.186.211.132.810.428.200'], ['H01.158.344.528', 'H01.158.782.236'], ['D02.078.370'], ['D02.522.352.506'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['D02.092.311.342.478.650', 'D02.455.426.559.389.657.166.175.342.478.6... | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-neovascular therapy by use of tumor neovasculature-targeted long-circulating liposome. | For the purpose of cancer anti-neovascular therapy (ANET), we previously isolated 5-mer peptide Ala-Pro-Arg-Pro-Gly (APRPG) that specifically bound to the tumor angiogenic site and observed that APRPG-modified liposomes encapsulating adriamycin were effective for the suppression of tumor in tumor-bearing mice. Since po... | ['Angiogenesis Inhibitors', 'Animals', 'Doxorubicin', 'Drug Carriers', 'Humans', 'Liposomes', 'Mice', 'Neoplasms, Experimental', 'Polyethylene Glycols', 'Recombinant Proteins', 'Tissue Distribution', 'Vascular Endothelial Growth Factor A'] | 15,491,809 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D26.255.260', 'E02.319.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The influence of neonatal orchiopexy upon the testis in persistent M?llerian duct syndrome. | We report on a patient with persistent m?llerian duct syndrome and normal external genitalia who had embryonal cancer of the testis 16 years after neonatal bilateral orchiopexy. In previous cases the testes of these patients have not been considered predisposed to form tumors. However, the occurrence of a testis tumor ... | ['Adolescent', 'Age Factors', 'Cryptorchidism', 'Disorders of Sex Development', 'Humans', 'Infant, Newborn', 'Karyotyping', 'Lymphocytes', 'Male', 'Mullerian Ducts', 'Spermatogenesis', 'Testicular Neoplasms', 'Testis'] | 6,113,287 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C12.294.829.258', 'C12.706.258', 'C16.131.939.258', 'C19.391.829.258'], ['C12.706.316', 'C13.351.875.253', 'C16.131.939.316', 'C19.391.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.500.385.315', 'E05.200.500.385.315... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Utilization management affects health care practices at Walter Reed Army Medical Center: analytical methods applied to decrease length of stay and assign appropriate level of care. | The Department of Defense has embraced utilization management (UM) as an important tool to control and possibly decrease medical costs. Budgetary withholds have been taken by the Office of the Assistant Secretary of Defense (Health Affairs) to encourage the military services to implement UM programs. In response, Walte... | ['Databases, Factual', 'Delivery of Health Care', 'District of Columbia', 'Hospitals, Military', 'Humans', 'Length of Stay', 'United States', 'Utilization Review'] | 10,628,158 | [['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['N04.590.374', 'N05.300'], ['Z01.107.567.875.500.210', 'Z01.433.429'], ['N02.278.421.510.180.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['Z01.107.567.875'], ['N04.761.879', 'N05.700.900']] | ['Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Effects of repeated cocaine injections on cochlear function. | The effects of repeated cocaine administration on cochlear function were evaluated by measuring amplitude-intensity and latency-intensity functions of the whole-nerve action potential of the auditory nerve. Whole-nerve action potential input/output functions obtained using tone-pips of 0.5, 1, 2, 4 and 8 kHz in a group... | ['Acoustic Stimulation', 'Adrenergic Fibers', 'Animals', 'Chinchilla', 'Cocaine', 'Cochlea', 'Dopamine beta-Hydroxylase', 'Drug Administration Schedule', 'Immunohistochemistry', 'Ketamine', 'Norepinephrine', 'Organ of Corti', 'Tyrosine 3-Monooxygenase'] | 7,704,608 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['A08.675.100.500', 'A08.675.542.075', 'A11.671.501.075'], ['B01.050'], ['B01.050.150.900.649.313.992.328'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['A09.246.300.246'], ['D08.811.682.690.708.292'], ['E02.319.283'], ['E01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapidly evolving genes of Drosophila: differing levels of selective pressure in testis, ovary, and head tissues between sibling species. | Investigations of rapidly evolving sex- and reproduction-related genes are expected to reveal important information about the process of speciation and species divergence. We screened testis, ovary, and head tissues to identify and characterize rapidly evolving genes (REGs) between closely related species. The results ... | ['Animals', 'Body Patterning', 'Drosophila', 'Evolution, Molecular', 'Female', 'Gene Expression Regulation, Developmental', 'Gene Library', 'Head', 'Male', 'Ovary', 'Phylogeny', 'Reproduction', 'Selection, Genetic', 'Species Specificity', 'Testis'] | 15,917,496 | [['B01.050'], ['G07.345.500.100'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['G05.045.250', 'G16.075.250'], ['G05.308.310'], ['G05.360.325'], ['A01.456'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G08.686.784'], ['G05.783'], ['G16.824'], ['A05.36... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Provider Experiences with Prison Care and Aftercare for Women with Co-occurring Mental Health and Substance Use Disorders: Treatment, Resource, and Systems Integration Challenges. | Incarcerated women with co-occurring mental health and substance use disorders (COD) face complex psychosocial challenges at community reentry. This study used qualitative methods to evaluate the perspectives of 14 prison and aftercare providers about service delivery challenges and treatment needs of reentering women ... | ['Adult', 'Aftercare', 'Diagnosis, Dual (Psychiatry)', 'Female', 'Health Resources', 'Health Services Needs and Demand', 'Humans', 'Mental Disorders', 'Mental Health', 'Prisoners', 'Prisons', 'Social Adjustment', 'Substance-Related Disorders'] | 24,595,815 | [['M01.060.116'], ['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['E01.190'], ['N03.349.340', 'N05.300.420'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F02.418', 'N01.400.500'], ['M01.729'], ['I01.880.604.787', 'J03.220.500'], ['F01.145.813.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
[Indications and concepts for plastic surgery therapy in chronic varicose ulcer]. | In the treatment of extensive leg ulcers, surgical therapy is superior to conservative methods in many respects. Radical resection of sclerotic tissue around the ulcer and its causing veins is essential, followed by defect cover with mesh-skin grafts. Surgery leads to prompt healing with a shortened hospitalization and... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bandages', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Skin Transplantation', 'Surgical Mesh', 'Varicose Ulcer', 'Wound Healing'] | 8,647,536 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E07.101'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quality, efficiency and integrity: value squeezes in management of hospital wards. | AIM: The aim of this study was to explore and describe the value squeezes experienced by ward managers in connection with quality management in hospital wards. The study focused on integrity pressure and coping strategies to deal with such pressure.BACKGROUND: Nurses in the role of ward managers have a key function in ... | ['Attitude of Health Personnel', 'Efficiency', 'Humans', 'Norway', 'Nurse Administrators', 'Qualitative Research', 'Quality Improvement', 'Quality of Health Care'] | 23,859,046 | [['F01.100.050', 'N05.300.100'], ['F02.784.692.351', 'N04.452.209'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.374'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580'], ['H01.770.644.241.850'], ['J01.293.754', 'N04.761.744'], ['N04.761', 'N05.715']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils. | Neutrophils migrate through endothelium using an ordered sequence of adhesive interactions and activating signals. To investigate the consequences of disruption of this sequence, we characterized adhesion and migration of neutrophils perfused over HUVEC that had been treated with TNF-alpha for 4 h and evaluated changes... | ['Cell Adhesion', 'Cell Migration Inhibition', 'Cells, Cultured', 'Chemokine CXCL1', 'Chemokine CXCL5', 'Chemokines, CXC', 'Chemotactic Factors', 'Chemotaxis, Leukocyte', 'Complement C5a', 'Dose-Response Relationship, Immunologic', 'Endothelium, Vascular', 'Growth Substances', 'Humans', 'Intercellular Signaling Peptide... | 10,820,279 | [['G04.022'], ['G04.198.337'], ['A11.251'], ['D12.644.276.374.200.120.050', 'D12.776.467.374.200.120.050', 'D12.776.624.664.700.049', 'D23.125.300.120.050', 'D23.469.200.120.050', 'D23.529.374.200.120.050'], ['D12.644.276.374.200.120.250', 'D12.776.467.374.200.120.250', 'D23.125.300.120.250', 'D23.469.200.120.250', 'D2... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diabetes knowledge--are patients getting the message? | Diabetes knowledge in a multi-ethnic population was assessed in 161 insulin treated diabetic patients using a 21-point multiple choice questionnaire translated into the appropriate languages. Our data showed a significant difference in diabetes knowledge related to ethnicity, being less in Asians and Afro-Caribbeans gr... | ['Adult', 'Africa', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Asia', 'Attitude to Health', 'Caribbean Region', 'Diabetes Mellitus, Type 1', 'Educational Status', 'Ethnic Groups', 'European Continental Ancestry Group', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Education as Topic', 'S... | 11,198,733 | [['M01.060.116'], ['Z01.058'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['Z01.252'], ['F01.100.150', 'N05.300.150'], ['Z01.107.084'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['N01.824.196'], ['... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Polyol-specific long-chain dehydrogenases/reductases of mannitol metabolism in Aspergillus fumigatus: biochemical characterization and pH studies of mannitol 2-dehydrogenase and mannitol-1-phosphate 5-dehydrogenase. | Functional genomics data suggests that the metabolism of mannitol in the human pathogen Aspergillus fumigatus involves the action of two polyol-specific long-chain dehydrogenases/reductases, mannitol-1-phosphate 5-dehydrogenase (M1PDH) and mannitol 2-dehydrogenase (M2DH). The gene encoding the putative M2DH was express... | ['Alanine', 'Aspergillus fumigatus', 'Base Sequence', 'Chromatography, Gel', 'Chromatography, Ion Exchange', 'DNA Primers', 'Electrophoresis, Polyacrylamide Gel', 'Hydrogen-Ion Concentration', 'Kinetics', 'Lysine', 'Mannitol', 'Mannitol Dehydrogenases', 'Mutagenesis, Site-Directed', 'Polymers', 'Recombinant Proteins', ... | 18,983,992 | [['D12.125.042'], ['B01.300.381.081.295'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.250'], ['E05.196.181.400.383'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D12.125.068.555', 'D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Artificial Lysosomal Platform to Study Nanoparticle Long-term Stability. | Nanoparticles (NPs) possess unique properties useful for designing specific functionalities for biomedi- cal applications. A prerequisite of a safe-by-design and effective use in any biomedical application is to study NP-cell interactions to gain a better understanding of cellular consequences upon exposure. Cellular u... | ['Gold', 'Lysosomes', 'Nanoparticles', 'Silicon Dioxide'] | 30,813,999 | [['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['A11.284.430.214.190.875.190.550'], ['J01.637.512.600'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pharmacokinetics of dexamethasone after intravenous and intramuscular administration in pigs. | The pharmacokinetics of dexamethasone (DEX) were investigated after an intravenous (IV) or intramuscular (IM) bolus injection of 0.3mg/kg bodyweight DEX sodium phosphate in pigs. The plasma concentrations of DEX were determined using a validated high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS)... | ['Animals', 'Area Under Curve', 'Biological Availability', 'Chromatography, Liquid', 'Dexamethasone', 'Female', 'Glucocorticoids', 'Injections, Intramuscular', 'Injections, Intravenous', 'Sus scrofa', 'Tandem Mass Spectrometry'] | 23,876,308 | [['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['G03.787.151', 'G07.690.725.129'], ['E05.196.181.400'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['E02.319.267.530.460'], ['E02.319.267.082.750', 'E02.319.267.530.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Age as a determinant of nutritional status: a cross sectional study. | BACKGROUND: Undenutrition is known to be prevalent and largely unrecognised in older patients; however, aberrations in indicators of nutritional status may simply reflect effects of age and/or functional disability.OBJECTIVE: The aim of this study was to measure the effect, if any of age on nutritional status in older ... | ['Aged', 'Aging', 'Analysis of Variance', 'Anthropometry', 'Ascorbic Acid', 'Body Mass Index', 'Body Weight', 'Calcifediol', 'Cross-Sectional Studies', 'Erythrocytes', 'Folic Acid', 'Health Status', 'Hemoglobins', 'Humans', 'Nutrition Assessment', 'Nutritional Status', 'Regression Analysis', 'Riboflavin', 'Serum Albumi... | 16,253,135 | [['M01.060.116.100'], ['G07.345.124'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells. | Hypotonicity-induced cell swelling is characterized by a modification in cell architecture associated with actin cytoskeleton remodeling. The ezrin/radixin/moesin (ERM) family proteins are important signal transducers during actin reorganization regulated by the monomeric G proteins of the Rho family. We report here th... | ['Actins', 'Amides', 'Animals', 'Calcium', 'Carbazoles', 'Cell Membrane', 'Cell Size', 'Cell Surface Extensions', 'Cells, Cultured', 'Enzyme Activation', 'Hypotonic Solutions', 'Indoles', 'Kidney Tubules, Collecting', 'Microfilament Proteins', 'Osmotic Pressure', 'Phosphorylation', 'Protein Binding', 'Protein Kinase C-... | 17,428,844 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D02.065'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.633.100.473.144', 'D03.633.300.148'], ['A11.284.149'], ['G04.325'], ['A11.284.180'], ['A11.251'], ['G02.111.263', 'G03.328'], ['D26.776.399'], ['D03.633.100.473'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription. | Nuclear receptors, including the androgen receptor (AR), regulate target cell transcription through interaction with auxiliary proteins to modify chromatin structure. We describe herein a novel AR-interacting protein, termed ARIP4, that has structural features typical of the SNF2-like protein family. With regard to the... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Amino Acid Sequence', 'Animals', 'Bacterial Proteins', 'COS Cells', 'Chlorocebus aethiops', 'DNA, Complementary', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Genes, Reporter', 'Insecta', 'Molecular Sequence Data', 'Nuclear Proteins', 'Receptors, Androg... | 12,058,073 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.097'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D13.444.308.497.220', 'D13.444.600.223... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient. | Previous work has shown that adriamycin can be accumulated into large unilamellar vesicle (LUV) systems in response to K+ diffusion potential established by valinomycin. It is demonstrated here that adriamycin can also be rapidly and efficiently accumulated into egg phosphatidylcholine (egg PC) and egg PC-cholesterol (... | ['Carbonyl Cyanide m-Chlorophenyl Hydrazone', 'Cholesterol', 'Doxorubicin', 'Egg Yolk', 'Hydrogen-Ion Concentration', 'Kinetics', 'Liposomes', 'Models, Biological', 'Phosphatidylcholines', 'Potassium'] | 3,964,703 | [['D02.442.288.200', 'D02.626.260'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['A16.690.325', 'G07.203.300.470.800', 'J02.500.470.800'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D25.479... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Light absorption of organic carbon emitted from burning wood, charcoal, and kerosene in household cookstoves. | Household cookstove emissions are an important source of carbonaceous aerosols globally. The light-absorbing organic carbon (OC), also termed brown carbon (BrC), from cookstove emissions can impact the Earth's radiative balance, but is rarely investigated. In this work, PM2.5 filter samples were collected during combus... | ['Absorption, Physicochemical', 'Aerosols', 'Air Pollutants', 'Biofuels', 'Biomass', 'Carbon', 'Charcoal', 'Climate', 'Kerosene', 'Light', 'Models, Chemical', 'Particulate Matter', 'Water', 'Wood'] | 29,729,570 | [['G01.015.249', 'G02.010.500'], ['D20.280.055', 'D26.255.165.055'], ['D27.888.284.101'], ['D20.147', 'N06.230.132.644.124'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D01.268.150'], ['D01.268.150.150'], ['G16.500.275.071', 'N06.230.300.100.250'], ['D20.345.630.600', 'N06.230.132.258.630.600'], ['G01.358.500.505.65... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Cross-sectional associations between different measures of obesity and muscle strength in men and women in a British cohort study. | OBJECTIVES: The relationship between obesity and grip strength, a key indicator of sarcopenia, has been inconsistently reported. We aimed to examine associations between grip strength and both body mass index (BMI), a clinical indicator of total adiposity, and waist circumference (WC), an indicator of central adiposity... | ['Abdominal Fat', 'Adiposity', 'Aged', 'Aged, 80 and over', 'Body Height', 'Body Mass Index', 'Body Weight', 'Cross-Sectional Studies', 'Female', 'Hand Strength', 'Humans', 'Male', 'Middle Aged', 'Muscle Strength', 'Muscle, Skeletal', 'Obesity', 'Obesity, Abdominal', 'Prospective Studies', 'Sarcopenia', 'United Kingdom... | 25,560,810 | [['A10.165.114.830.500'], ['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', '... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Enhancing ascorbate in fruits and tubers through over-expression of the L-galactose pathway gene GDP-L-galactose phosphorylase. | Ascorbate, or vitamin C, is obtained by humans mostly from plant sources. Various approaches have been made to increase ascorbate in plants by transgenic means. Most of these attempts have involved leaf material from model plants, with little success reported using genes from the generally accepted l-galactose pathway ... | ['Actinidia', 'Amino Acid Sequence', 'Ascorbic Acid', 'Biosynthetic Pathways', 'Fragaria', 'Fruit', 'Galactose', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Guanosine Diphosphate', 'Lycopersicon esculentum', 'Molecular Sequence Data', 'Organ Size', 'Phosphoric Monoester Hydrolases', 'Plant Leaves', 'Plant Pro... | 22,129,455 | [['B01.650.940.800.575.912.250.341.500.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['G02.111.098', 'G03.493.100'], ['B01.650.940.800.575.912.250.859.937.500.266'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D09.947.875.359.377'], ['G05.308.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.