Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Activation of human spleen glucocerebrosidases by monoacylglycol sulfates and diacylglycerol sulfates. | The study of the acidic lipid requirement of human spleen glucocerebrosidase was extended to include two new series of acidic lipids, namely, monoacylglycol sulfates and diacylglycerol sulfates. Lysosomal glucocerebrosidase was extracted with sodium cholate and 1-butanol to render its beta-glucosidase activity dependen... | ['Citrates', 'Citric Acid', 'Diglycerides', 'Enzyme Activation', 'Gaucher Disease', 'Glucosidases', 'Glucosylceramidase', 'Glycerides', 'Humans', 'Kinetics', 'Micelles', 'Phosphates', 'Spleen', 'Structure-Activity Relationship', 'Sulfates'] | 3,355,173 | [['D02.241.081.901.434'], ['D02.241.081.901.434.249'], ['D10.351.303'], ['G02.111.263', 'G03.328'], ['C10.228.140.163.100.435.825.400', 'C16.320.565.189.435.825.400', 'C16.320.565.398.641.803.441', 'C16.320.565.595.554.825.400', 'C18.452.132.100.435.825.400', 'C18.452.584.687.803.441', 'C18.452.648.189.435.825.400', 'C... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exploring brain functions in autism spectrum disorder: A systematic review on functional near-infrared spectroscopy (fNIRS) studies. | A growing body of research has investigated the functional development of the brain in autism spectrum disorder (ASD). Functional near-infrared spectroscopy (fNIRS) is increasingly being used in this respect. This method has several advantages over other functional neuroimaging techniques in studying brain functions in... | ['Autism Spectrum Disorder', 'Brain', 'Humans', 'Nerve Net', 'Social Perception', 'Spectroscopy, Near-Infrared'] | 30,664,885 | [['F03.625.164.113'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.511'], ['F02.463.593.752'], ['E01.370.350.750', 'E05.196.867.851']] | ['Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of montelukast sodium on the duration of effusion of otitis media. | This study tests the hypothesis that montelukast sodium, a selective leukotriene receptor antagonist, will decrease the duration of the effusion of otitis media. Tympanometry and spectral gradient acoustic reflectometry were used to confirm the effusion of otitis media in patients between 2 and 12 years of age. Patient... | ['Acetates', 'Child', 'Child, Preschool', 'Double-Blind Method', 'Female', 'Humans', 'Leukotriene Antagonists', 'Male', 'Otitis Media with Effusion', 'Placebos', 'Quinolines', 'Treatment Outcome'] | 15,248,005 | [['D02.241.081.018', 'D10.251.400.045'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.347.565', 'D27.505.696.399.450.565'], ['C09.218.705.663.670'], ['D26.660', 'E02.785'], ['D03.633.100... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Signs of steroid myopathy in a group of patients with asthma undergoing continuous steroid therapy]. | The 35 patients with bronchial asthma undergoing continuous steroid therapy were examined in order to reveal any signs of steroid myopathy. More than 80% of patients complained of muscle weakness. In the physical examination the motor function was correct in the majority of patients. Muscular enzymes and blood electrol... | ['Adolescent', 'Adult', 'Aged', 'Asthma', 'Electromyography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Muscular Diseases', 'Steroids'] | 2,637,433 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.651', 'C10.668.491'], ['D04.210.500']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Conservative treatment of isolated fractures of the medial malleolus. | Between 1992 and 2000, 57 patients with 57 isolated fractures of the medial malleolus were treated conservatively by immobilisation in a cast. The results were assessed by examination, radiography and completion of the short form-36 questionnaire and American Orthopaedic Foot and Ankle Society ankle-hindfoot score. Of ... | ['Adolescent', 'Adult', 'Aged', 'Ankle Injuries', 'Ankle Joint', 'Casts, Surgical', 'Female', 'Follow-Up Studies', 'Fracture Fixation', 'Fracture Healing', 'Fractures, Bone', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Range of Motion, Articular', 'Retrospective Studies', 'Treatment Outcome'] | 17,259,423 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C26.558.100'], ['A02.835.583.378.062'], ['E07.858.442.660.430.500', 'E07.858.690.725.430.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300'], ['G16.762.891.500'], ['C26.404'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytotoxic phenotype of tumor infiltrating lymphocytes in medullary carcinoma of the breast. | Medullary carcinoma (MC) of the breast is considered to carry a more favorable prognosis than other subtypes of infiltrating ductal carcinoma This is a biological paradox because its clinical behavior contrasts with its anaplastic morphology. MC is characterized by a dense lymphocytic infiltrate. In this study, we dete... | ['Adult', 'Aged', 'Breast Neoplasms', 'Carcinoma, Medullary', 'Cell Differentiation', 'Female', 'Humans', 'Immunohistochemistry', 'Immunophenotyping', 'Lymphocytes, Tumor-Infiltrating', 'Middle Aged', 'T-Lymphocytes, Cytotoxic'] | 10,574,602 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.465.625.650.240.315', 'C04.557.470.200.025.370.315', 'C04.557.470.615.315', 'C04.557.580.625.650.240.315'], ['G04.152'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.5... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultra-fine structural characterization and bioactivity evaluation of TiO2 nanotube layers. | For an application as biomedical materials of high performance with a good biocompatibility, the TiO2 nanotube-type oxide film on Ti substrate has been fabricated by electrochemical method, and the effects of surface characteristics of TiO2 naotube layer have been investigated. The surface morphology of TiO2 nanotube l... | ['Microscopy, Electron, Scanning', 'Nanotubes', 'Spectrum Analysis', 'Titanium', 'X-Ray Diffraction', 'X-Rays'] | 19,198,362 | [['E01.370.350.515.402.541', 'E05.595.402.541'], ['J01.637.512.850'], ['E05.196.867'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Solubilization of proteins from human lymph node tissue and two-dimensional gel storage. | In the present study, we compared six different solubilization buffers and optimized two-dimensional electrophoresis (2-DE) conditions for human lymph node proteins. In addition, we developed a simple protocol for 2-D gel storage. Efficient solubilization was obtained with lysis buffers containing (a) 8 M urea, 4% CHAP... | ['Buffers', 'Carcinoma, Squamous Cell', 'Cells', 'Detergents', 'Electrophoresis, Gel, Two-Dimensional', 'Head and Neck Neoplasms', 'Humans', 'Isoelectric Focusing', 'Lymph Nodes', 'Neoplasm Proteins', 'Proteins', 'Solubility', 'Time'] | 16,584,638 | [['D27.720.470.280'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11'], ['D27.720.877.265', 'J01.516.381'], ['E05.196.401.250', 'E05.301.300.230'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.401.663', 'E05.301.300.663'], ['A10.549.400', 'A15.382.520.604.412'], ['D12.776.624'], ['... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Cross-stressor immunization against the behavioral deficits introduced by uncontrollable shock. | Exposure to inescapable shock disrupted performance in both shock- and water-escape tasks. These deficits were prevented in mice that were previously trained in the same task. However, an asymmetrical immunization effect was seen in a cross-stressor paradigm. Whereas deficits of water-escape performance engendered by i... | ['Animals', 'Arousal', 'Electroshock', 'Escape Reaction', 'Helplessness, Learned', 'Hippocampus', 'Humans', 'Hypothalamus', 'Male', 'Muridae', 'Norepinephrine', 'Serotonin'] | 6,683,562 | [['B01.050'], ['F02.830.104', 'G11.561.035'], ['E05.723.402.403', 'F04.669.224'], ['F01.145.113.780.688', 'F01.145.367', 'F01.145.875.439.500.688', 'G07.568.500.590.688', 'G11.427.410.568.850.688'], ['F01.393.398', 'F02.463.425.420'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bromadiolone poisoning leading to subarachnoid haemorrhage: A case report and review of the literature. | WHAT IS KNOWN AND OBJECTIVE: Many cases of rodenticide poisoning have been reported. Bromadiolone, often called a super-warfarin, is a second-generation dicoumarin rodenticide with long half-life. The main clinical manifestations of bromadiolone poisoning are excessive or inappropriate bleeding of skin mucosa, digestiv... | ['4-Hydroxycoumarins', 'Adult', 'Blood Coagulation', 'Female', 'Humans', 'Prothrombin Time', 'Rodenticides', 'Subarachnoid Hemorrhage'] | 31,556,967 | [['D03.383.663.283.446.520', 'D03.633.100.150.446.520'], ['M01.060.116'], ['G09.188.390.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.625.115.610', 'E05.200.625.115.610', 'G09.188.680'], ['D27.720.031.700.853', 'D27.888.723.853'], ['C10.228.140.300.535.800', 'C14.907.253.573.800', 'C23.550.414.9... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of ouabain on relaxation induced by cromakalim in human and canine mesenteric arteries. | We investigated the effect of cromakalim, a K+ channel opener, that activates indirectly the Na(+)-K+ pump, in association with increased K+ conductance in the mesenteric arteries. In 65% of human mesenteric arteries tested, the concentration-dependent relaxation curves for cromakalim were biphasic: the low concentrati... | ['Adult', 'Animals', 'Benzopyrans', 'Cromakalim', 'Dogs', 'Female', 'Glyburide', 'Humans', 'Male', 'Mesenteric Arteries', 'Middle Aged', 'Muscle, Smooth, Vascular', 'Ouabain', 'Pyrroles', 'Rubidium Radioisotopes', 'Sensitivity and Specificity', 'Sodium Radioisotopes', 'Sodium-Potassium-Exchanging ATPase', 'Vasodilator ... | 8,383,059 | [['M01.060.116'], ['B01.050'], ['D03.383.663.283', 'D03.633.100.150'], ['D03.383.129.578.150', 'D03.383.663.283.455', 'D03.633.100.150.455'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.065.950.828.575', 'D02.886.590.795.575'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.565'], ['M01.060.116.6... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Correlation between the age-related memory impairment and the level of free Ca(2+) in brain synaptosomes]. | In this study, We investigated the changes in the ability of learning-memory of 12-month- and 18-month-old mice, and the intrasynaptosomal Ca(2+) levels of some mouse brain areas (hippocampus, cerebral cortex, corpus quadrigem and cerebellum) on the basis of our last behavior observation and biochemistry detection. Mea... | ['Aging', 'Animals', 'Brain', 'Calcium', 'Discrimination Learning', 'Learning', 'Male', 'Memory', 'Memory Disorders', 'Mice', 'Synaptosomes'] | 11,971,178 | [['G07.345.124'], ['B01.050'], ['A08.186.211'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['F02.463.425.280'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.835.859']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of antioxidative, chelating, and DNA-protective effects of selected essential oil components (eugenol, carvacrol, thymol, borneol, eucalyptol) of plants and intact Rosmarinus officinalis oil. | Selected components of plant essential oils and intact Rosmarinus officinalis oil (RO) were investigated for their antioxidant, iron-chelating, and DNA-protective effects. Antioxidant activities were assessed using four different techniques. DNA-protective effects on human hepatoma HepG2 cells and plasmid DNA were eval... | ['Antioxidants', 'Camphanes', 'Chelating Agents', 'Cyclohexanols', 'Cymenes', 'DNA Damage', 'Eucalyptol', 'Eugenol', 'Hep G2 Cells', 'Humans', 'Hydrogen Peroxide', 'Monoterpenes', 'Oils, Volatile', 'Plant Oils', 'Plasmids', 'Rosmarinus', 'Thymol'] | 24,955,655 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.100.080.050.500', 'D02.455.426.100.080.550.234', 'D02.455.849.575.141.500', 'D04.075.080.500.234'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['D02.455.426.559.389.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vascular corrosion casting technique steps. | The vascular corrosion casting technique produces a replica of vascular beds of normal or pathological tissues. Once associated with scanning electron microscopy (SEM), this technique provides details of the three-dimensional anatomic arrangement of the vascular replica, which is the main advantage of this method. The ... | ['Animals', 'Capillaries', 'Corrosion Casting', 'Microscopy, Electron, Scanning', 'Neovascularization, Physiologic', 'Wound Healing'] | 17,477,397 | [['B01.050'], ['A07.015.461.165'], ['E01.370.225.500.620.620.150', 'E01.370.225.750.600.620.150', 'E05.200.500.620.620.150', 'E05.200.750.600.620.150'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G09.330.630'], ['G16.762.891']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outside-in signaling from integrin alpha IIb beta 3 into platelets in the absence of agonist-induced signaling. | Platelet agonists generate intracellular signals which lead to activation of the platelet membrane glycoprotein IIb-IIIa (integrin alpha IIb beta 3). The resulting occupancy of alpha IIb beta 3 by ligands also generates signals into the cell (outside-in signaling). We reported previously that unlike platelet agonists, ... | ['Antibodies, Monoclonal', 'Blood Platelets', 'Calcium', 'Cell Adhesion Molecules', 'Enzyme Precursors', 'Fibrinogen', 'Focal Adhesion Kinase 1', 'Focal Adhesion Protein-Tyrosine Kinases', 'Humans', 'Immunoglobulin Fab Fragments', 'Intracellular Signaling Peptides and Proteins', 'Phosphorylation', 'Platelet Activation'... | 9,195,778 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.118.188', 'A15.145.229.188'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D08.622', 'D12.776.811.243'], ['D12.776.124.050.250', 'D12.776.1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterizing uptake kinetics of PAHs from the air using polyethylene-based passive air samplers of multiple surface area-to-volume ratios. | Polyethylene passive sampling devices (PSDs) were deployed to investigate how passive samplers of multiple surface area-to-volume ratios could be used to characterize uptake kinetics for polyaromatic hydrocarbons (PAHs). Theoretically, uptake profiles for different thickness PSDs of the same surface area should show th... | ['Air Pollutants', 'Environmental Monitoring', 'Kinetics', 'Models, Theoretical', 'Molecular Weight', 'Polycyclic Aromatic Hydrocarbons', 'Reproducibility of Results'] | 15,180,068 | [['D27.888.284.101'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.374.661', 'G02.111.490'], ['E05.599'], ['G02.494'], ['D02.455.426.559.847', 'D04.615'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Diagnostic approach in mechanical jaundice, complicated by purulent cholangitis]. | Up-to-date high-informative non-invasive diagnostic methods were used in 54 patients with obstructive jaundice (OJ) complicated by purulent cholangitis (PC). Treatment-diagnostic algorithm can to improve results of diagnosis. This algorithm is the following: ultrasonic examination as a screening method; if a case of ja... | ['Cholangitis', 'Cholestasis', 'Humans', 'Magnetic Resonance Imaging', 'Suppuration'] | 12,861,724 | [['C06.130.120.200'], ['C06.130.120.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C01.830', 'C23.550.470.756']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Menstrual cycle characteristics in women with persistent schizophrenia. | OBJECTIVE: Oestradiol has been implicated in the pathogenesis of schizophrenia. Women with schizophrenia often suffer with menstrual dysfunction, usually associated with low oestradiol levels, but whether menstrual dysfunction has an effect on their psychiatric symptoms is not well researched. The aim of this study is ... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Depression', 'Estradiol', 'Female', 'Humans', 'Menstrual Cycle', 'Menstruation Disturbances', 'Middle Aged', 'Schizophrenia', 'Young Adult'] | 26,070,315 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.605'], ['C23.550.568'], ['M01.060.116.630'], ['F03.700.750'], ['M01.06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hereditary spherocytosis with band 3 deficiency. Association with a nonsense mutation of the band 3 gene (allele Lyon), and aggravation by a low-expression allele occurring in trans (allele Genas). | We describe an 18-year-old with moderate hereditary spherocytosis. The condition was associated with a 35% decrease in band 3. The underlying mutation was Arg to stop at codon 150 (CGA-->TGA) and was designated R150X, which defined allele Lyon of the EPB3 gene. The inheritance pattern was dominant. However, the mother,... | ['Alleles', 'Anion Exchange Protein 1, Erythrocyte', 'Base Sequence', 'Heterozygote', 'Humans', 'Infant', 'Male', 'Molecular Sequence Data', 'Point Mutation', 'Polymorphism, Single-Stranded Conformational', 'Spherocytosis, Hereditary'] | 8,704,215 | [['G05.360.340.024.340.030'], ['D12.776.157.530.450.162.193.500', 'D12.776.157.530.450.437.249.500', 'D12.776.157.530.937.656.249.500', 'D12.776.543.550.190.276.500', 'D12.776.543.550.779.249.500', 'D12.776.543.585.450.162.193.500', 'D12.776.543.585.450.437.249.500', 'D12.776.543.585.937.776.249.500'], ['G02.111.570.08... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Innovation, public choice and public control in the market for health insurance. | Innovation, public choice and public control in the market for health insurance/benefits in the United States are largely dependent upon the ability of the various stakeholders to successfully argue their positions with legislators, regulators, providers, purchasers and third party beneficiaries. Given the public/priva... | ['Choice Behavior', 'Conflict of Interest', 'Health Benefit Plans, Employee', 'Health Care Sector', 'Health Expenditures', 'Humans', 'Insurance, Health', 'Investments', 'Organizational Innovation', 'Policy Making', 'Private Sector', 'Public Sector', 'United States'] | 10,387,155 | [['F02.463.785.373.346'], ['K01.752.566.479.095', 'N05.350.225'], ['N01.824.417.700.325', 'N03.219.521.576.343.290', 'N04.452.677.800.325'], ['J01.576.489', 'N03.219.650'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['N03.219.702'], ['N04.452.610'], ['N... | ['Psychiatry and Psychology [F]', 'Humanities [K]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Influence of fluoxymesterone on in vitro erythropoiesis affected by leukemic cells. | To investigate the influence of nonlymphocytic leukemic cells on normal erythropoietic burst-forming units (BFU-E), we cocultured leukemic cells at concentrations ranging from 0.5 to 5.0 X 10(5)/ml with 2 X 10(5) blood mononuclear cells or marrow nucleated cells from normal subjects in a BFU-E assay. The inhibitory eff... | ['Adult', 'Aged', 'Cell Line', 'Erythropoiesis', 'Female', 'Fluoxymesterone', 'Humans', 'Leukemia, Myeloid', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged'] | 6,584,313 | [['M01.060.116'], ['M01.060.116.100'], ['A11.251.210'], ['G04.152.825.414', 'G09.188.343.414'], ['D04.210.500.054.079.429.154.349', 'D04.210.500.908.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539'], ['C04.557.337.539.275'], ['M01.060.116.630']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Xanthogranulomatous pyelonephritis in a renal allograft. | We report a case of xanthogranulomatous pyelonephritis in a cadaver kidney allograft. The patient had diabetic glomerulosclerosis. The predisposing factors that led to this condition included hyperglycemia, a previous rejection reaction and Escherichia coli urinary infection. Persistent fever, pyuria, bacilluria and a ... | ['Adult', 'Escherichia coli Infections', 'Female', 'Humans', 'Kidney Transplantation', 'Postoperative Complications', 'Pyelonephritis, Xanthogranulomatous', 'Transplantation, Homologous', 'Urinary Tract Infections'] | 3,057,233 | [['M01.060.116'], ['C01.150.252.400.310.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['C23.550.767'], ['C12.777.419.570.643.790.810', 'C12.777.419.570.821.717.810', 'C13.351.968.419.570.643.790.810', 'C13.351.968.419.570.821.717.810'], ['E04.936.864'], [... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Radiofrequency ablation of rabbit liver: correlation between CT findings and pathological findings]. | The purpose of this study was to present the time-related imaging findings and correlative pathological findings of irradiated regions in the rabbit liver. RF ablation was carried out on 16 rabbit livers. Irradiated regions were imaged at 3 days, 4 weeks, and 12 weeks. At 3 days, the regions showed a two-zone structure... | ['Animals', 'Catheter Ablation', 'Liver', 'Rabbits', 'Time Factors', 'Tomography, X-Ray Computed'] | 11,828,758 | [['B01.050'], ['E02.808.750.500', 'E04.014.760.500'], ['A03.620'], ['B01.050.150.900.649.313.968.700'], ['G01.910.857'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of pneumococcal conjugate vaccination on nasopharyngeal carriage in children with early onset of acute otitis media - a randomized controlled trial. | CONCLUSION: Although children vaccinated with heptavalent pneumococcal conjugate vaccine (PCV) had fewer episodes of acute otitis media (AOM), this trial was unable to prove a simultaneous decrease in nasopharyngeal carriage.OBJECTIVE: Carriage rates of AOM pathogens in the nasopharynx are high among children, and colo... | ['Acute Disease', 'Age Factors', 'Carrier State', 'Female', 'Haemophilus influenzae', 'Heptavalent Pneumococcal Conjugate Vaccine', 'Humans', 'Infant', 'Male', 'Moraxella catarrhalis', 'Nasopharynx', 'Otitis Media', 'Pneumococcal Vaccines', 'Recurrence', 'Risk Factors', 'Streptococcus pneumoniae', 'Streptococcus pyogen... | 25,496,176 | [['C23.550.291.125'], ['N05.715.350.075', 'N06.850.490.250'], ['N06.850.520.169'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['D20.215.894.135.750.600.500', 'D20.215.894.815.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['B03.440.400.425.537.525.200', 'B03.660.250.530.525.200'],... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of self-administered and rater-administered methods of assessing levels of severity of depression in elderly patients. | Eighty consecutive attenders (M age = 75 years) in a primary care group practice associated with a teaching hospital in New York were assessed for depression using a self-administered questionnaire, the Zung Self-Rating Depression Scale (SDS), and a rater-administered interview, the Short-CARE. The sample was 75% femal... | ['Aged', 'Depression', 'Female', 'Humans', 'Interview, Psychological', 'Male', 'Psychiatric Status Rating Scales', 'Self-Assessment', 'Surveys and Questionnaires'] | 3,418,040 | [['M01.060.116.100'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['F04.711.513.653'], ['F01.752.747.792.537'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome. | The fragile histidine triad (FHIT) gene plays an important role in anti-cancer and the abnormal methylation of FHIT gene is found in many carcinomas. The epigenetic changes of tumor suppressor genes (TSG) are now recognized as an abnormal mechanism contributing to the development of myelodysplastic syndrome (MDS). To c... | ['Acid Anhydride Hydrolases', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'DNA Methylation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myelodysplastic Syndromes', 'Neoplasm Proteins', 'Prognosis'] | 18,367,246 | [['D08.811.277.040'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C15.378.190.625'], ['D12.776.624'], ['E01.789']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Direct synthesis of sensitive selenocysteine peptides by the Ugi reaction. | Ammonia and selenoaldehydes are both problematic components in Ugi reactions. Here we report the efficient direct multicomponent synthesis of sensitive selenocysteine peptides without the use of convertible (protected) primary amines, including suitable deprotection protocols for selenols. | ['Carbonates', 'Molecular Structure', 'Peptides', 'Selenocysteine', 'Trifluoroethanol'] | 23,114,693 | [['D01.045.125', 'D01.200.275.150', 'D01.248.497.158.165'], ['G02.111.570', 'G02.466'], ['D12.644'], ['D02.731.600', 'D02.886.030.230.700', 'D12.125.166.230.700'], ['D02.033.375.880']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Different cortical activity in reading of Kanji words, Kana words and Kana nonwords. | We report a positron emission tomography study on reading of Japanese Kanji (morphograms) words, Kana (phonograms) words and Kana nonwords using statistical parametric mapping. Activity was more pronounced in the lateral fusiform gyrus (Area 37) in Kanji, in contrast to the greater activation in the middle and inferior... | ['Adolescent', 'Adult', 'Brain Mapping', 'Cerebral Cortex', 'Cognition', 'Female', 'Form Perception', 'Handwriting', 'Humans', 'Japan', 'Male', 'Reading', 'Tomography, Emission-Computed'] | 10,666,563 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['F02.463.188'], ['F02.463.593.373', 'F02.463.593.778.435'], ['L01.559.423.906.539'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['L01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Biplane angiography for experimental validation of computational fluid dynamic models of blood flow in artificial lungs. | This article presents an investigation into the validation of velocity fields obtained from computational fluid dynamic (CFD) models of flow through the membrane oxygenators using x-ray digital subtraction angiography (DSA). Computational fluid dynamic is a useful tool in characterizing artificial lung devices, but num... | ['Angiography, Digital Subtraction', 'Computer Simulation', 'Models, Cardiovascular', 'Models, Theoretical', 'Oxygenators, Membrane'] | 23,820,279 | [['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['L01.224.160'], ['E05.599.395.161'], ['E05.599'], ['E07.652.582']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A role for the RabA4b effector protein PI-4Kbeta1 in polarized expansion of root hair cells in Arabidopsis thaliana. | The RabA4b GTPase labels a novel, trans-Golgi network compartment displaying a developmentally regulated polar distribution in growing Arabidopsis thaliana root hair cells. GTP bound RabA4b selectively recruits the plant phosphatidylinositol 4-OH kinase, PI-4Kbeta1, but not members of other PI-4K families. PI-4Kbeta1 c... | ['1-Phosphatidylinositol 4-Kinase', 'Arabidopsis', 'Arabidopsis Proteins', 'Binding Sites', 'Biological Transport', 'Calcimycin', 'Calcium-Binding Proteins', 'Cell Enlargement', 'Cell Polarity', 'Ionophores', 'Microscopy, Electron', 'Mutation', 'Plant Roots', 'Protein Binding', 'Two-Hybrid System Techniques', 'rab4 GTP... | 16,567,499 | [['D08.811.913.696.620.550'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.120'], ['G03.143'], ['D03.633.100.221.173'], ['D12.776.157.125'], ['G04.161.500', 'G07.345.249.410.500'], ['G04.250'], ['D27.505.519.562.374', 'D27.720.395'], ['E01.370.350.515.402', 'E05.595.402'], ['G05.365.590']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Impetigo neonatorum congenita caused by B-streptococci (author's transl)]. | The growing incidence among newborns of B-streptococcal diseases has been accompanied by the appearance of less common findings, such as Impetigo neonatorum bullosa. The pathological pattern is described. Brief reference is made to literature. | ['Humans', 'Impetigo', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Skin Diseases, Vesiculobullous', 'Streptococcal Infections', 'Streptococcus agalactiae'] | 7,008,460 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.868.951.360', 'C01.150.252.410.890.587', 'C01.150.252.819.770.360', 'C01.800.720.770.360', 'C17.800.838.765.770.360'], ['M01.060.703.520'], ['C16.614'], ['C17.800.865'], ['C01.150.252.410.890'], ['B03.353.750.737.872.100', 'B03.510.400.800.872.100', 'B... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multi-centre study of intraurethral valve-pump catheter in women with a hypocontractile or acontractile bladder. | OBJECTIVES: To compare the safety, effectiveness and patient satisfaction of an intraurethral valve-pump catheter (In-Flow) versus the current standard of care, clean intermittent catheterization (CIC), for females with hypocontractile or acontractile bladder.MATERIALS AND METHODS: The study was a multi-centre, prospec... | ['Adult', 'Aged', 'Cross-Over Studies', 'Equipment Design', 'Equipment Safety', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'North America', 'Patient Satisfaction', 'Prospective Studies', 'Quality of Life', 'Treatment Outcome', 'Urinary Bladder Diseases', 'Urinary Catheterization', 'Urinary Incontinence', '... | 15,964,124 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.320'], ['E05.330'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.567'], ['F01.100.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Comparative estimation of open and mini-invasive interventions in the treatment of hepatic abscesses and accumulations of liquid of postoperative genesis]. | A comparative aspect of the treatment results for pyogenic hepatic abscesses and extraorgan accumulations of postoperative liquid, using transcutaneous ultrasonografically controlled and open-access interventions, was studied up in 328 patients. The efficacy and concurrent ability of miniinvasive technologies in such p... | ['Drainage', 'Humans', 'Liver Abscess, Pyogenic', 'Minimally Invasive Surgical Procedures', 'Postoperative Complications', 'Prospective Studies', 'Treatment Outcome', 'Ultrasonography, Interventional'] | 23,610,810 | [['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.830.025.020.455.730', 'C06.552.597.758'], ['E04.502'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['E01.370.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
National estimates of the use of hematopoietic stem-cell transplantation in children with cancer in the United States. | National utilization data for hematopoietic stem-cell transplantation (HSCT) for childhood cancers in the United States have not been reported. We identified cancer encounters for children aged 18 years and younger from 1997 to 2001 in US nonfederal, acute care hospitals. We compared patient, hospital, and resource use... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Hospital Costs', 'Hospital Mortality', 'Humans', 'Male', 'Neoplasms', 'Retrospective Studies', 'United States'] | 15,995,713 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adult body size and physical activity in relation to risk of breast cancer according to tumor androgen receptor status. | BACKGROUND: Obesity and physical activity have been hypothesized to affect breast cancer risk partly via the androgen signaling pathway. We conducted the first study to evaluate these associations by tumor androgen receptor (AR) status.METHODS: Height, weight, and physical activity were assessed using questionnaires in... | ['Adult', 'Age Factors', 'Biomarkers, Tumor', 'Body Size', 'Body Weight', 'Breast Neoplasms', 'Exercise', 'Female', 'Follow-Up Studies', 'Humans', 'Immunoenzyme Techniques', 'Middle Aged', 'Motor Activity', 'Neoplasm Staging', 'Nursing Staff', 'Obesity', 'Postmenopause', 'Prognosis', 'Receptors, Androgen', 'Receptors, ... | 25,855,627 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D23.101.140'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C04.588.180', 'C17.800.090.500'], ['G11.... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Antibiotic use on German pig farms - A longitudinal analysis for 2011, 2013 and 2014. | To study antibiotic use in livestock in a temporal context with the development of antimicrobial resistance, long-term changes in antibiotic use must be mapped and their possible causes must be explored. Therefore, the present work assesses the changes in antibiotic use over time in German livestock husbandry. In addit... | ['Animals', 'Anti-Bacterial Agents', 'Cross-Sectional Studies', 'Drug Utilization', 'Farms', 'Germany', 'History, 21st Century', 'Longitudinal Studies', 'Regression Analysis', 'Swine'] | 29,969,477 | [['B01.050'], ['D27.505.954.122.085'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.452.706.477'], ['J01.040.372', 'J03.540.150'], ['Z01.542.315'], ['K01.400.504.984'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E05.318.740.750', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Morphological changes during maturation of starfish oocytes: surface ultrastructure and cortical actin. | The cell surface and extracellular investments of oocytes of the starfish Pisaster ochraceus are analyzed by Nomarski differential interference contrast microscopy and by scanning electron microscopy. The investing coats include a thin sheet of follicle cells, a jelly coat, and a vitelline layer; their morphologies are... | ['Actins', 'Adenine', 'Animals', 'Extracellular Space', 'Female', 'Meiosis', 'Microscopy, Electron, Scanning', 'Oocytes', 'Oogenesis', 'Ovarian Follicle', 'Ovum', 'Starfish'] | 6,683,686 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D03.633.100.759.138'], ['B01.050'], ['A10.082.500', 'A11.284.295'], ['G04.144.220.220.687', 'G05.113.220.687'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A05.360.490.690.680', 'A11.497.497.600'], ['G04.152.650.249', 'G08.686.784.310.500']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Basal and stretch-augmented natriuretic peptide secretion by quiescent rat atria. | Absolute rates of immunoreactive atrial natriuretic peptide (ANP) secretion were measured in vitro at 37 degrees C in noncontracting preparations of combined right and left rat atria at constant distending pressures of 0 or 5.1 mmHg in presence of 0.2 mM extracellular Ca2+ concentration [( Ca2+]o), 10 microM ryanodine,... | ['Amiloride', 'Animals', 'Atrial Function', 'Atrial Natriuretic Factor', 'Cadmium', 'Calcium Channel Blockers', 'Female', 'Heart', 'Heart Atria', 'In Vitro Techniques', 'Kinetics', 'Microscopy, Electron', 'Myocardial Contraction', 'Rats', 'Rats, Inbred Strains', 'Ryanodine', 'Saxitoxin', 'Tetrodotoxin', 'Thermodynamics... | 2,146,883 | [['D03.383.679.149'], ['B01.050'], ['G09.330.040'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['A07.541'], ['A07.541.358'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions. | Of 89 patients receiving nightly subcutaneous deferoxamine for transfusion-dependent thalassemia major or Diamond-Blackfan anemia, 13 presented with visual loss or deafness of acute onset or both. Detailed ophthalmologic, audiologic, and evoked-potential studies uncovered abnormalities caused by neurotoxicity in 27 mor... | ['Adolescent', 'Adult', 'Age Factors', 'Anemia, Aplastic', 'Audiometry', 'Child', 'Child, Preschool', 'Color Vision Defects', 'Deferoxamine', 'Evoked Potentials, Auditory', 'Evoked Potentials, Visual', 'Ferritins', 'Hearing Loss, Sensorineural', 'Humans', 'Infusions, Parenteral', 'Injections, Subcutaneous', 'Pigment Ep... | 3,485,251 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C15.378.071.085', 'C15.378.190.223.250'], ['E01.370.382.375.060'], ['M01.060.406'], ['M01.060.406.448'], ['C10.597.751.941.256', 'C11.270.151.500', 'C11.966.256', 'C23.888.592.763.941.256'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['G0... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gastric electrical stimulation with Enterra therapy improves symptoms of idiopathic gastroparesis. | BACKGROUND: Gastric electrical stimulation (GES) is a therapeutic option for intractable symptoms of gastroparesis (GP). Idiopathic GP (ID-GP) represents a subset of GP.AIMS: A prospective, multicenter, double-blinded, randomized, crossover study to evaluate the safety and efficacy of Enterra GES in the treatment of ch... | ['Adult', 'Cross-Over Studies', 'Double-Blind Method', 'Electric Stimulation Therapy', 'Electrodes, Implanted', 'Female', 'Gastroparesis', 'Humans', 'Male', 'Middle Aged', 'Treatment Outcome', 'Vomiting', 'Young Adult'] | 23,895,180 | [['M01.060.116'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E07.305.250.319', 'E07.695.202'], ['C06.405.748.543', 'C23.888.592.636.263'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exposure duration: effects on eyewitness accuracy and confidence. | The current study examined the relationship between the length of exposure to a face in an eyewitness setting and identification accuracy and confidence. A sample of 164 young (ages 17-25) and older (ages 59-81) adults viewed a simulated crime in which they saw the culprit's face for a short (12 s) or long (45 s) durat... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Recognition, Psychology', 'Repression, Psychology', 'Space Perception', 'Surveys and Questionnaires', 'Time Factors', 'Visual Perception'] | 14,511,547 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.425.540.706'], ['F01.393.821'], ['F02.463.593.778'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['G01.910.857'], ['F02.463.593.932']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adsorption and oxidation of 3-nitro-1,2,4-triazole-5-one (NTO) and its transformation product (3-amino-1,2,4-triazole-5-one, ATO) at ferrihydrite and birnessite surfaces. | The emerging insensitive munitions compound (IMC) 3-nitro-1,2,4-triazole-5-one (NTO) is currently being used to replace conventional explosives such as 1,3,5-trinitro-1,3,5-triazacyclohexane (RDX), but the environmental fate of this increasingly widespread IMC remains poorly understood. Upon release from unexploded sol... | ['Adsorption', 'Amitrole', 'Biotransformation', 'Explosive Agents', 'Ferric Compounds', 'Groundwater', 'Kinetics', 'Models, Chemical', 'Nitro Compounds', 'Oxidation-Reduction', 'Oxides', 'Triazoles', 'Urea'] | 29,738,948 | [['G01.030', 'G02.020'], ['D03.383.129.799.100'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D27.720.317'], ['D01.490.100'], ['G01.311.355'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['D02.640'], ['G02.700', 'G03.295.531'], ['D01.248.497.158.685', 'D01.650.550'], ['D03.383.129.799'], ['D02.065.950']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Injury deaths in the adolescent population of Finland: a 43-year secular trend analysis between 1971 and 2013. | BACKGROUND: Injuries are a major public health problem worldwide, being the leading cause of death in children and adolescents in developed countries. However, knowledge on recent secular trends in injury deaths of adolescents is sparse.METHODS: Using Official Cause-of-Death Statistics of Finland, we examined the natio... | ['Accidental Falls', 'Accidents, Traffic', 'Adolescent', 'Age Distribution', 'Cause of Death', 'Child', 'Drowning', 'Female', 'Finland', 'Follow-Up Studies', 'Homicide', 'Humans', 'Incidence', 'Male', 'Sex Distribution', 'Suicide', 'Wounds and Injuries', 'Young Adult'] | 26,701,984 | [['N06.850.135.122'], ['N06.850.135.392'], ['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.060.406'], ['C23.550.260.393', 'C26.304', 'N06.850.135.696'], ['Z01.542.816.186'], ['... | ['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Genetic (idiopathic) generalized epilepsy with occipital semiology. | Idiopathic photosensitive occipital lobe epilepsy (IPOE) is a syndrome that should be suspected in patients with seizures with occipital semiology, photosensitivity, and normal MRI. It should be distinguished from occipital epilepsy of unknown aetiology (cryptogenic) given the differences in management. We reviewed pat... | ['Adult', 'Electroencephalography', 'Epilepsy, Generalized', 'Epilepsy, Reflex', 'Female', 'Humans', 'Male', 'Occipital Lobe', 'Young Adult'] | 30,361,187 | [['M01.060.116'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375'], ['C10.228.140.490.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.571'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Fresh Pair of Eyes: A Blind Observation Method for Evaluating Social Skills of Children with ASD in a Naturalistic Peer Situation in School. | The Social skills Observation Measure (SOM) is a direct observation method for social skills used in naturalistic everyday situations in school. This study describes the development of the SOM and investigates its psychometric properties in 86 children with Autism spectrum disorder, aged 9.8-13.1 years. The interrater ... | ['Adolescent', 'Autism Spectrum Disorder', 'Child', 'Female', 'Humans', 'Male', 'Observation', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Reproducibility of Results', 'Schools', 'Social Adjustment', 'Social Skills'] | 27,289,230 | [['M01.060.057'], ['F03.625.164.113'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.249'], ['F04.711.513.653'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['I02.783', 'J03.832'], ['F01.145.813.621'], ['F01.145.813.828', 'F01.829.401.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Identification of the histidine residues involved in substrate recognition by a rat H+/peptide cotransporter, PEPT1. | The LLC-PK1 cells stably transfected with a rat PEPT1 cDNA transported ceftibuten (anion) and cephradine (zwitterion), both oral beta-lactam antibiotics, in a H+-gradient-dependent manner. Diethylpyrocarbonate, a histidine residue modifier, abolished ceftibuten uptake. This inhibition was prevented in the presence of g... | ['Animals', 'Blotting, Western', 'Carrier Proteins', 'Ceftibuten', 'Cephalosporins', 'Cephradine', 'Diethyl Pyrocarbonate', 'Dipeptides', 'Histidine', 'Hydrogen-Ion Concentration', 'LLC-PK1 Cells', 'Microscopy, Fluorescence', 'Mutagenesis, Site-Directed', 'Oocytes', 'Peptide Transporter 1', 'Plasmids', 'Rats', 'Recombi... | 8,843,163 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.157'], ['D02.065.589.099.249.187', 'D02.886.665.074.187', 'D03.633.100.300.249.187'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['D02.065.589.099.249.200.185', 'D02.886.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Susceptibility of Ixodes scapularis (Acari: Ixodidae) to Metarhizium brunneum F52 (Hypocreales: Clavicipitaceae) using three exposure assays in the laboratory. | An emulsifiable concentrate (EC) and granular (G) formulation of the entomopathogenic fungus, Metarhizium brunneum strain F52 (formerly Metarhizium anisopliae strain F52) were tested against unfed adults and nymphs of Ixodes scapularis Say in the laboratory. Three exposure methods; dip, surface contact, and direct spra... | ['Animals', 'Biological Control Agents', 'Female', 'Ixodes', 'Larva', 'Logistic Models', 'Male', 'Metarhizium', 'Nymph', 'Pest Control, Biological'] | 22,420,275 | [['B01.050'], ['D20.215.113'], ['B01.050.500.131.166.132.832.400.425'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06.850.520.830.500.525',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
CXCR4-transgene expression significantly improves marrow engraftment of cultured hematopoietic stem cells. | Hematopoietic stem cells (HSCs) lose marrow reconstitution potential during ex vivo culture. HSC migration to stromal cell-derived factor (SDF)-1 (CXCL12) correlates with CXC chemokine receptor 4 (CXCR4) expression and marrow engraftment. We demonstrate that mobilized human CD34+ peripheral blood stem cells (CD34+ PBSC... | ['Animals', 'Antigens, CD34', 'Bone Marrow Cells', 'Calcium', 'Cell Movement', 'Flow Cytometry', 'Gene Transfer Techniques', 'Graft Survival', 'Hematopoietic Stem Cell Transplantation', 'Hematopoietic Stem Cells', 'Humans', 'Membrane Glycoproteins', 'Mice', 'Mice, SCID', 'NADPH Oxidase 2', 'NADPH Oxidases', 'Receptors,... | 15,579,633 | [['B01.050'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['A11.148', 'A15.378.316'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.198', 'G07.568.500.180'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.24... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila. | Animals execute one particular behavior among many others in a context-dependent manner, yet the mechanisms underlying such behavioral choice remain poorly understood. Here we studied how two fundamental behaviors, sex and sleep, interact at genetic and neuronal levels in Drosophila. We show that an increased need for ... | ['Animals', 'Courtship', 'DNA-Binding Proteins', 'Drosophila Proteins', 'Drosophila melanogaster', 'Female', 'Male', 'Nerve Tissue Proteins', 'Neurons', 'Sex Characteristics', 'Sexual Behavior, Animal', 'Sleep', 'Transcription Factors'] | 28,754,889 | [['B01.050'], ['F01.145.802.279'], ['D12.776.260'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D12.776.631'], ['A08.675', 'A11.671'], ['G08.686.815'], ['F01.145.113.252.748'], ['F02.830.855', 'G11.561.803'], ['D12.776.930']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Light traffic: photo-crosslinking a novel transport system. | The Tat protein transporter is found in the membranes of many bacteria and in plant chloroplasts. This highly unusual transport machine moves folded and often oligomeric substrate proteins across energy-conserving membranes. A recent paper reports the first use of a photo-crosslinking approach to dissect the early reco... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Arginine', 'Bacteria', 'Bacterial Proteins', 'Biological Transport', 'Chloroplasts', 'Consensus Sequence', 'Cross-Linking Reagents', 'Escherichia coli Proteins', 'Gene Products, tat', 'Light', 'Lysine', 'Membrane Transport Proteins', 'Models, Biol... | 15,106,605 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['B03'], ['D12.776.097'], ['G03.143'], ['A11.284.430.214.190.875.700.140'], ['G02.111.570.580.175'], ['D27.720.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Levosimendan improves renal function in patients with acute decompensated heart failure: comparison with dobutamine. | BACKGROUND: Levosimendan is a relatively new cardiac inotropic agent with calcium sensitizing activity. This study was conducted to investigate the effects of levosimendan (L) and dobutamine (D) on renal function in patients hospitalized with decompensated heart failure (HF).METHOD: The present study included 88 consec... | ['Acute Disease', 'Aged', 'Cardiotonic Agents', 'Dobutamine', 'Female', 'Glomerular Filtration Rate', 'Heart Failure', 'Humans', 'Hydrazones', 'Kidney', 'Male', 'Middle Aged', 'Pyridazines', 'Simendan', 'Urination'] | 17,952,581 | [['C23.550.291.125'], ['M01.060.116.100'], ['D27.505.954.411.222', 'D27.720.799.080'], ['D02.092.311.220', 'D02.092.471.683.410', 'D02.455.426.559.389.657.166.175.220'], ['E01.370.390.400.300', 'G08.852.357'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442.288'], ['A05.810.453'], ['M01.060.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of an Automatic Alpine Skiing Turn Detection Algorithm Based on a Simple Sensor Setup. | In order to gain insight into skiing performance, it is necessary to determine the point where each turn begins. Recent developments in sensor technology have made it possible to develop simpler automatic turn detection methodologies, however they are not feasible for regular use. The aim of this study was to develop a... | ['Algorithms', 'Biomechanical Phenomena', 'Biosensing Techniques', 'Humans', 'Movement', 'Skiing', 'Video Recording'] | 30,795,560 | [['G17.035', 'L01.224.050'], ['G01.154.090', 'G01.374.089'], ['E05.601.043'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['I03.450.642.845.787.500'], ['L01.280.960']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Herbicide resistance from a divided EPSPS protein: the split Synechocystis DnaE intein as an in vivo affinity domain. | We report that the N- and C-terminal splicing domains of the intein found in the dnaE gene of Synechocystis sp. PCC6803 (Ssp DnaE intein) are capable of association in vivo and in vitro, even with key splicing residues changed to alanine (Cys(1), Asn(159), and Cys(+1) to Ala). These studies utilized the herbicide resis... | ['3-Phosphoshikimate 1-Carboxyvinyltransferase', 'Alkyl and Aryl Transferases', 'Binding Sites', 'Binding, Competitive', 'Cyanobacteria', 'DNA Polymerase III', 'DNA Transposable Elements', 'Drug Resistance', 'Escherichia coli', 'Gene Library', 'Glycine', 'Herbicides', 'Mutagenesis, Insertional', 'Peptide Fragments', 'P... | 11,223,241 | [['D08.811.913.225.735'], ['D08.811.913.225'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['B03.280', 'B03.440.475.100'], ['D08.811.913.696.445.308.300.235'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['G07.690.773.984'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biotin holocarboxylase synthetase: purification from rat liver cytosol and some properties. | The purification of biotin holocarboxylase synthetase (EC 6.3.4.10) from rat liver cytosol to a much higher degree of purity than previously reported, is described. The specific enzymatic activity of the final preparation is increased about 7,000 fold over the starting material. The purified preparation elutes from a g... | ['Animals', 'Carbon-Nitrogen Ligases', 'Chromatography, Affinity', 'Chromatography, Gel', 'Chromatography, Ion Exchange', 'Cytosol', 'Electrophoresis, Polyacrylamide Gel', 'Kinetics', 'Ligases', 'Liver', 'Molecular Weight', 'Rats', 'Rats, Inbred F344'] | 7,849,632 | [['B01.050'], ['D08.811.464.259'], ['E05.196.181.400.170'], ['E05.196.181.400.250'], ['E05.196.181.400.383'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['E05.196.401.402', 'E05.301.300.319'], ['G01.374.661', 'G02.111.490'], ['D08.811.464'], ['A03.620'], ['G02.494'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Loss of the third C2H2 zinc finger of chicken KLF7 affects its transcriptional regulation activities in adipose tissue. | KLF7, one of candidate genes in neurotherapy and metabolic syndrome, has been studied in adipogenesis of mammalian species and birds. However, the effect of the third C2H2 zinc finger of KLF7 for its transcriptional regulation in adipogenesis has not been well understood. Here, the wild-type chicken KLF7 (KLF7) overexp... | ['Adipogenesis', 'Adipose Tissue', 'Animals', 'Binding Sites', 'CCAAT-Enhancer-Binding Protein-alpha', 'CYS2-HIS2 Zinc Fingers', 'Cell Line', 'Chickens', 'Fatty Acid Synthase, Type I', 'Fatty Acid-Binding Proteins', 'Gene Expression Regulation', 'Kruppel-Like Transcription Factors', 'Lipoprotein Lipase', 'Mutant Protei... | 31,828,306 | [['G04.152.149'], ['A10.165.114'], ['B01.050'], ['G02.111.570.120'], ['D12.776.260.108.124.500', 'D12.776.660.167.500', 'D12.776.930.127.124.500'], ['G02.111.570.820.709.275.500.985.250'], ['A11.251.210'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D08.811.277.352.897.387.100', 'D08.811.520.241.3... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A semi-automated method for bone age assessment using cervical vertebral maturation. | OBJECTIVE: To propose a semi-automated method for pattern classification to predict individuals' stage of growth based on morphologic characteristics that are described in the modified cervical vertebral maturation (CVM) method of Baccetti et al.MATERIALS AND METHODS: A total of 188 lateral cephalograms were collected,... | ['Age Determination by Skeleton', 'Bayes Theorem', 'Cephalometry', 'Cervical Vertebrae', 'Decision Support Techniques', 'Female', 'Humans', 'Male', 'Software'] | 22,059,467 | [['E01.370.049', 'E01.370.350.700.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['A02.835.232.834.151'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
New homoserine lipids from Xerocomus langbianensis. | New diacylglycerotrimethyl homoserine lipids 1 (2 O,3 O-bislinolylglycero-4'-O-(N,N,N-trimethyl)homoserine) and 2 (2 O,3 O-linolyl-palmitylglycero-4'-O-(N,N,N-trimethyl)-homoserine) were isolated from the fruiting body of a Vietnamese species of Xerocomus langbianensis. The chemical structures were settled on the basis... | ['Basidiomycota', 'Diglycerides', 'Homoserine', 'Lipids'] | 11,981,878 | [['B01.300.179'], ['D10.351.303'], ['D12.125.526'], ['D10']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TRI2SOLID: an application of reverse engineering methods to the creation of CAD models of bone segments. | For many biomechanical engineering activities it would be useful to have the three dimensional (3D) geometry of bone segments available in form of vectorial models within computer aided design (CAD) environments. In this paper a new method for the semi-automatic conversion of a stack of CT images of a femur into a CAD ... | ['Algorithms', 'Computer Simulation', 'Computer-Aided Design', 'Femur', 'Humans', 'Mathematical Computing', 'Models, Anatomic', 'Radiology Information Systems', 'Tomography, X-Ray Computed'] | 9,725,647 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['L01.224.108.150', 'L01.296.110.150'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.680'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['N04.452.515.825'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.35... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Benign paroxysmal positional vertigo following septorhinoplasty. | We present 2 cases of benign paroxysmal positional vertigo (BPPV) following septorhinoplasty. Benign paroxysmal positional vertigo following septorhinoplasty is an unusual entity. Two young women who had difficulty in breathing and nasal deformity underwent septorhinoplasty. On the second and the third postoperative da... | ['Adult', 'Benign Paroxysmal Positional Vertigo', 'Female', 'Humans', 'Rhinoplasty', 'Vertigo'] | 23,348,352 | [['M01.060.116'], ['C09.218.568.900.883.500', 'C10.597.951.500', 'C23.888.592.958.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.755', 'E04.580.392.500', 'E04.680.650'], ['C09.218.568.900.883', 'C10.597.951', 'C23.888.592.958']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential expression of two zebrafish emx homeoprotein mRNAs in the developing brain. | The complete amino-acid sequences of two zebrafish emx homeoproteins containing a homeodomain homologous to that of the Drosophila empty spiracles head gap gene product have been determined by cloning and sequencing of cDNAs. The zebrafish emx1 and emx2 homeoproteins consist of 233 and 247 amino acids, respectively. Th... | ['Amino Acid Sequence', 'Animals', 'Autoradiography', 'Base Sequence', 'Blotting, Northern', 'Brain', 'Brain Chemistry', 'DNA Primers', 'Embryo, Nonmammalian', 'Homeodomain Proteins', 'In Situ Hybridization', 'Molecular Sequence Data', 'RNA, Messenger', 'Transcription Factors', 'Zebrafish'] | 8,592,638 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['D13.695.578.424.450.275', 'D27.720.470.530... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pharmacologic rationale for regional drug delivery. | Regional drug delivery is an approach designed to improve the selectivity of chemotherapy. When compared with systemic drug administration, regional delivery can potentially increase drug concentrations at tumor sites and/or lower systemic drug exposure. Pharmacokinetic analysis can evaluate or even predict the relativ... | ['Antineoplastic Agents', 'Chemotherapy, Cancer, Regional Perfusion', 'Humans', 'Infusions, Intra-Arterial', 'Injections, Intraperitoneal', 'Injections, Intravenous', 'Injections, Spinal', 'Kinetics', 'Mathematics', 'Metabolic Clearance Rate', 'Microspheres', 'Neoplasms'] | 6,547,166 | [['D27.505.954.248'], ['E02.319.267.200', 'E04.292.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510.520'], ['E02.319.267.530.490'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['E02.319.267.530.580'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['E01.370.225.843', 'E05.200.843', 'G03.490',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel word acquisition in aphasia: Facing the word-referent ambiguity of natural language learning contexts. | Recent research suggests that some people with aphasia preserve some ability to learn novel words and to retain them in the long-term. However, this novel word learning ability has been studied only in the context of single word-picture pairings. We examined the ability of people with chronic aphasia to learn novel wor... | ['Adolescent', 'Adult', 'Aged', 'Aphasia', 'Female', 'Humans', 'Language', 'Learning', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Neuropsychological Tests', 'Recognition, Psychology', 'Verbal Learning', 'Young Adult'] | 27,085,892 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540.407'], ['M01.060.116.630'], ['F04.711.513'], ['F02.463.425.54... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice. | Three members of the Src family of tyrosine kinases, src, fyn, and yes, are broadly expressed throughout mouse development. Mutations in the c-src and fyn genes were shown previously to lead to restricted nonoverlapping phenotypes only in a subset of cells in which these kinases are expressed. In this work we show that... | ['Animals', 'Base Sequence', 'CSK Tyrosine-Protein Kinase', 'Crosses, Genetic', 'DNA Primers', 'Female', 'Gene Expression Regulation, Developmental', 'Genes, src', 'Kidney', 'Male', 'Mice', 'Mice, Mutant Strains', 'Molecular Sequence Data', 'Phenotype', 'Protein-Tyrosine Kinases', 'Proto-Oncogene Proteins', 'Proto-Onco... | 7,958,873 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.696.620.682.725.800.158'], ['E05.393.281'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.310'], ['G05.360.340.024.340.375.500.791.570'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of Pseudomonas aeruginosa exotoxin-A on the synthesis and secretion of proteins in isolated rat pancreatic acini. | Exposure of isolated rat dispersed pancreatic acini to increasing concentrations (10 to 1000 ng/ml) of purified exotoxin-A from Pseudomonas aeruginosa resulted in a progressive inhibition of 3H-leucine incorporation into "cellular" (those remaining in the cells) and "secretory" (those released into the medium) proteins... | ['ADP Ribose Transferases', 'Amylases', 'Animals', 'Bacterial Toxins', 'Chymotrypsinogen', 'Exotoxins', 'Male', 'Pancreas', 'Protein Biosynthesis', 'Pseudomonas aeruginosa', 'Rats', 'Rats, Inbred Strains', 'Time Factors', 'Trypsinogen', 'Virulence Factors'] | 2,579,650 | [['D08.811.913.400.725.115'], ['D08.811.277.450.066'], ['B01.050'], ['D23.946.123'], ['D08.622.184', 'D12.776.811.243.184'], ['D23.946.350'], ['A03.734'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterisation of a thermostable alpha-amylase from Bacillus brevis. | Biochemical characterization of a novel heat-stable alpha-amylase, produced by a thermophilic strain of Bacillus brevis, has been made. The pattern of the enzyme action on different substrates was studied. It was found that reducing groups were rapidly liberated from amylopectin, soluble and insoluble starch compared t... | ['Amino Acids', 'Bacillus', 'Carbohydrates', 'Enzyme Stability', 'Hot Temperature', 'Kinetics', 'Substrate Specificity', 'Thermodynamics', 'alpha-Amylases'] | 1,628,658 | [['D12.125'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['D09'], ['E05.916.360', 'G02.111.700.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.38... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Influence of complex reagents on removal of chromium(VI) by zero-valent iron. | The removal of Cr(VI) by zero-valent iron (Fe(0)) and the effect of three complex reagents, ethylenediaminetetraacetic acid (EDTA), NaF and 1,10-phenanthroline, on this reaction were investigated using batch reactors at pH values of 4, 5 and 6. The results indicate that the removal of Cr(VI) by Fe(0) is slow at pH 5.0 ... | ['Catalysis', 'Chromium', 'Edetic Acid', 'Environmental Pollutants', 'Hydrogen-Ion Concentration', 'Indicators and Reagents', 'Iron', 'Oxidation-Reduction', 'Phenanthrolines', 'Sodium Fluoride'] | 18,486,963 | [['G02.130'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['D27.888.284'], ['G02.300'], ['D27.720.470.410'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G02.700', 'G03.295.531'], ['D03.633.300.669'], ['D01.303.350.300.875', 'D01.857.725... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Quantitative effects of composting state variables on C/N ratio through GA-aided multivariate analysis. | It is widely known that variation of the C/N ratio is dependent on many state variables during composting processes. This study attempted to develop a genetic algorithm aided stepwise cluster analysis (GASCA) method to describe the nonlinear relationships between the selected state variables and the C/N ratio in food w... | ['Algorithms', 'Biodegradation, Environmental', 'Carbon', 'Cluster Analysis', 'Models, Chemical', 'Multivariate Analysis', 'Nitrogen', 'Refuse Disposal', 'Soil', 'Soil Pollutants', 'Waste Products'] | 21,257,193 | [['G17.035', 'L01.224.050'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.268.150'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.599.495'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['D01.268.604', 'D01.362.625'], ['N06.850.780.200.800.800.700',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Placebo-controlled trials in schizophrenia: are they ethical? Are they necessary? | The current controversy as to the proper role of the placebo control in the evaluation of new treatments for schizophrenia requires an analysis that is sensitive to both ethical and scientific issues. Clinical equipoise, widely regarded as the moral foundation of the randomized controlled trial (RCT), requires the use ... | ['Antipsychotic Agents', 'Controlled Clinical Trials as Topic', 'Ethics, Medical', 'Humans', 'Patient Compliance', 'Research Design', 'Schizophrenia'] | 10,093,865 | [['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.318.372.250.250.365', 'N05.715.360.330.250.250.365', 'N06.850.520.450.250.250.365'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.600', 'F01... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The Effects of Sleep Problems on the Trajectory of Antisocial Behavior from Adolescence through Early Adulthood in Taiwan: Family Functioning as a Moderator. | STUDY OBJECTIVES: To examine the longitudinal relationship between sleep problems and development of antisocial behavior from adolescence through young adulthood, and to investigate whether family functioning moderates the association being examined. Potential sex differences were also explored.METHODS: A total of 2,49... | ['Adolescent', 'Antisocial Personality Disorder', 'Conduct Disorder', 'Family Relations', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Prospective Studies', 'Risk Factors', 'Sex Factors', 'Sleep Wake Disorders', 'Taiwan', 'Young Adult'] | 27,166,239 | [['M01.060.057'], ['F03.675.050'], ['F03.625.094.300'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Reduced scytonemin isolated from Nostoc commune induces autophagic cell death in human T-lymphoid cell line Jurkat cells. | Nostoc commune is a terrestrial benthic blue-green alga that often forms an extended mucilaginous layer on the soil, accumulates on stones and mud in aquatic environments. Reduced-scytonemin (R-scy), isolated from N. commune Vaucher, has been shown to suppress the human T-lymphoid Jurkat cell growth. To reveal the mech... | ['Autophagy', 'Cell Line', 'Humans', 'Indoles', 'Jurkat Cells', 'Microtubule-Associated Proteins', 'Mitochondria', 'Nostoc commune', 'Oxidative Stress', 'Phenols', 'Reactive Oxygen Species', 'Vacuoles'] | 23,876,822 | [['G04.011'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567.569.440'], ['D12.776.220.600.450', 'D12.776.631.560'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['B03.280.575.150', 'B03.440.475.100.575.150... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the immediate effects of five beta-adrenoreceptor-blocking drugs with different ancillary properties in angina pectoris. | We compared the immediate effects of five beta-adrenoreceptor-blocking agents in 16 patients with stable angina pectoris. Acute dose-response studies showed that all five drugs improved exercise tolerance and reduced ST-segment depression, heart rate and blood pressure by a similar degree in comparison with a placebo (... | ['Adult', 'Angina Pectoris', 'Blood Pressure', 'Dose-Response Relationship, Drug', 'Drug Evaluation', 'Electrocardiography', 'Exercise Test', 'Heart Rate', 'Humans', 'Male', 'Metoprolol', 'Middle Aged', 'Oxprenolol', 'Practolol', 'Propanolamines', 'Propranolol'] | 581,782 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Kinetics of the incorporation of tropoelastin into elastic fibers in embryonic chick aorta. | Matrix-free cells isolated by enzymic digestion of chick embryo aortas were labeled with [14C]proline for 20 to 60 min and the kinetics of the secretion of tropoelastin were followed by chasing the label and assaying [14C]tropoelastin in the cells and in the medium. The results indicated that secretion of tropoelastin ... | ['Animals', 'Aorta', 'Chick Embryo', 'Elastic Tissue', 'Elastin', 'Kinetics', 'Macromolecular Substances', 'Proline', 'Solubility', 'Tropoelastin'] | 6,218,959 | [['B01.050'], ['A07.015.114.056'], ['A13.350.150', 'A16.331.200'], ['A10.165.400'], ['D05.750.078.421', 'D12.776.860.300.350'], ['G01.374.661', 'G02.111.490'], ['D05'], ['D12.125.072.401.623'], ['G02.805'], ['D12.776.811.850', 'D12.776.860.300.350.700']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vitamin D-associated genetic variation and risk of breast cancer in the breast and prostate cancer cohort consortium (BPC3). | BACKGROUND: Two recent genome-wide association studies (GWAS) identified SNPs in or near four genes related to circulating 25-hydroxyvitamin D [25(OH)D] concentration. To examine the hypothesized inverse relationship between vitamin D status and breast cancer, we studied the associations between SNPs in these genes and... | ['Breast Neoplasms', 'Cohort Studies', 'Female', 'Genetic Predisposition to Disease', 'Genetic Variation', 'Genome-Wide Association Study', 'Humans', 'Male', 'Polymorphism, Single Nucleotide', 'Prostatic Neoplasms', 'Vitamin D'] | 25,542,828 | [['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.365'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Immunotherapy-related adverse effects on 18 | 18F-Fluorodeoxyglucose positron emission tomography/CT imaging plays a key role in oncological imaging including in staging, radiotherapy planning, treatment response and recurrence assessment. Immunotherapies represent a major advance in cancer therapy for a number of tumours with resulting survival benefit. However, ... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Agents, Immunological', 'B7-H1 Antigen', 'CTLA-4 Antigen', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Immunotherapy', 'Immunotherapy, Adoptive', 'Male', 'Middle Aged', 'Neoplasms', 'Positron Emission Tomography Computed Tomography', 'Programmed Cell Death 1 Receptor', '... | 32,105,505 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248.384'], ['D12.776.465.625', 'D12.776.467.150.300', 'D12.776.543.095.300', 'D23.050.301.285.400', 'D23.529.168.300'], ['D12.776.465.782', 'D12.776.543.750.705.222.750', 'D23.050.301.264.894.158', 'D23.101.100.894.158'], ['D09.254.229.500'], ['B01.050.150.90... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stent-assisted Gugliemi detachable coil repair of wide-necked renal artery aneurysm using 3-D angiography. | PURPOSE: To report a wide-necked renal artery aneurysm treated successfully with stent-assisted Gugliemi detachable coil occlusion, assisted by three-dimensional (3-D) angiography.CASE REPORT: A 56-year-old woman with history of hypertension presented with a 2.5-cm wide-necked saccular aneurysm involving her distal rig... | ['Aneurysm', 'Angiography, Digital Subtraction', 'Catheterization', 'Embolization, Therapeutic', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Magnetic Resonance Angiography', 'Middle Aged', 'Radiographic Image Interpretation, Computer-Assisted', 'Radiography, Interventional', 'Renal Artery', 'Renal Circulation', ... | 18,166,635 | [['C14.907.055'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['E02.148', 'E05.157'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500.50... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Prognostic implications of hypoglycaemic episodes during hospitalisation for myocardial infarction in patients with type 2 diabetes: a report from the DIGAMI 2 trial. | OBJECTIVE: To explore if hypoglycaemic episodes during hospitalisation influence the subsequent prognosis in patients with diabetes and acute myocardial infarction.DESIGN, SETTING AND PATIENTS: Within the framework of the clinical trial DIGAMI 2 hypoglycaemic episodes (blood glucose <3.0 mmol/l with or without symptoms... | ['Aged', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Female', 'Follow-Up Studies', 'Hospitalization', 'Humans', 'Hyperglycemia', 'Hypoglycemia', 'Hypoglycemic Agents', 'Insulin', 'Male', 'Myocardial Infarction', 'Prognosis', 'Prospective Studies', 'Regression Analysis', 'Treatment Outcome'] | 19,029,171 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure and expression of a barley acidic beta-glucanase gene. | A barley acidic beta-1,3-glucanase gene was recovered from a barley genomic library by homology with a partial cDNA of barley basic beta-1,3-glucanase isoenzyme GII. The gene, Abg2, is homologous to the PR2 family of pathogenesis-related beta-1,3-glucanase genes. The ABG2 protein has 81% amino acid similarity to barley... | ['Acids', 'Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'Escherichia coli', 'Gene Expression', 'Genes, Plant', 'Genome', 'Glucan Endo-1,3-beta-D-Glucosidase', 'Hordeum', 'Molecular Sequence Data', 'Plant Proteins', 'RNA, Messenger', 'Recombinant Proteins', 'Restriction Mapping', 'Seeds', 'Sequence Analy... | 8,507,835 | [['D01.029'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340'], ['D08.811.277.450.420.200.600'], ['B01.650.940.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response. | Leukocyte transendothelial migration (TEM) is a tightly regulated, multistep process that is critical to the inflammatory response. A transient increase in endothelial cytosolic free calcium ion concentration (?[Ca(2+)]i) is required for TEM. However, the mechanism by which endothelial ?[Ca(2+)]i regulates TEM and the ... | ['Animals', 'Calcium', 'Cell Movement', 'Cytosol', 'Egtazic Acid', 'Endothelial Cells', 'Humans', 'Inflammation', 'Leukocytes', 'Mice', 'Mice, Inbred C57BL', 'Platelet Endothelial Cell Adhesion Molecule-1', 'TRPC Cation Channels', 'TRPC6 Cation Channel'] | 26,392,222 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.198', 'G07.568.500.180'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['A11.118.637... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exposure to violence among urban school-aged children: is it only on television? | OBJECTIVE: To measure exposure to different types of violence among school-aged children in a primary care setting.DESIGN: Child interviews using an instrument measuring 4 types of exposure (direct victimization, witnessing, hearing reports, media). Violent acts measured include being beaten up, chased/threatened, robb... | ['Child', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Mass Media', 'Multivariate Analysis', 'New York', 'Pediatrics', 'Regression Analysis', 'Surveys and Questionnaires', 'Urban Population', 'Violence'] | 11,044,149 | [['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.590'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['Z01.107.567.875.075.437', 'Z01.107.567.875.350.530', 'Z01.107.567.875.500.53... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Ultra-rapid freezing of human multipronuclear zygotes using electron microscope grids. | Developmental capacity of human multipronuclear (PN) zygotes cryopreserved using an ultra-rapid freezing method and electron microscope (EM) grids was studied. Multipronuclear zygotes obtained from a human IVF programme were used as an alternative to normal 2PN zygotes; they were divided into 3PN or >or =4PN zygotes an... | ['Cell Nucleus', 'Cell Survival', 'Cryopreservation', 'Humans', 'Microscopy, Electron', 'Time Factors', 'Zygote'] | 10,920,104 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.346'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['G01.910.857'], ... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monomer-to-dimer transition of Brucella suis type IV secretion system component VirB8 induces conformational changes. | Secretion systems are protein complexes essential for bacterial virulence and potential targets for antivirulence drugs. In the intracellular pathogen Brucella suis, a type IV secretion system mediates the translocation of virulence factors into host cells and it is essential for pathogenicity. VirB8 is a core componen... | ['Bacterial Proteins', 'Brucella suis', 'Crystallography, X-Ray', 'Dimerization', 'Fluorometry', 'Micelles', 'Molecular Docking Simulation', 'Nuclear Magnetic Resonance, Biomolecular', 'Periplasm', 'Protein Conformation', 'Type IV Secretion Systems'] | 28,236,662 | [['D12.776.097'], ['B03.440.400.425.215.500.750', 'B03.660.050.070.100.750'], ['E05.196.309.742.225'], ['G02.206', 'G03.230'], ['E05.196.712.516.600'], ['D05.374', 'D26.255.560'], ['E05.599.595.249', 'L01.224.160.249'], ['E05.196.867.519.550'], ['A11.284.295.680'], ['G02.111.570.820.709'], ['D05.500.890.500.937']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Duplication of 111 bases in exon 1 of the CYP21 gene is combined with deletion of CYP21P-C4B genes in steroid 21-hydroxylase deficiency. | Congenital adrenal hyperplasia (CAH) is a common autosomal recessive disorder mainly caused by defects in the steroid 21-hydroxylase (CYP21) gene. A 9.3-kb fragment generated by NdeI and AseI digestion by Southern blot analysis indicated that a consequence of deletion of the C4-CYP21 repeat module was the production of... | ['Adrenal Hyperplasia, Congenital', 'Alleles', 'Base Sequence', 'Complement C4b', 'Crossing Over, Genetic', 'DNA Mutational Analysis', 'Humans', 'Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Recombinant Fusion Proteins', 'Sequence Deletion', 'Steroid 21-Hydroxylase'] | 12,855,227 | [['C12.706.316.090.500', 'C13.351.875.253.090.500', 'C16.131.939.316.129.500', 'C16.320.033', 'C16.320.565.925.249', 'C18.452.648.925.249', 'C19.053.440', 'C19.391.119.090.500'], ['G05.360.340.024.340.030'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.124.486.274.350.260'], ['G05.728.615.200'],... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phenotypic and genotypic identification of yeasts from cheese. | Eighty-five years strains isolated from different cheeses of Austria, Denmark, France, Germany, and Italy were identified using physiological methods and genotypically using random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR) analysis. Good congruence was found between the phenotypic and genotypic dat... | ['Cheese', 'Genetic Markers', 'Genotype', 'Mycological Typing Techniques', 'Phenotype', 'Random Amplified Polymorphic DNA Technique', 'Yeasts'] | 10,510,714 | [['G07.203.200.500.444', 'G07.203.300.350.300.444', 'J02.350.500.444', 'J02.500.350.300.444'], ['D23.101.387', 'G05.695.450'], ['G05.380'], ['E01.370.225.875.610', 'E05.200.875.610'], ['G05.695'], ['E05.393.620.500.687', 'E05.601.700'], ['B01.300.930']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Influence of radiation doses in local radiotherapy on anti-tumor immunity and tumor metastasis]. | The relationship between radiation doses and the subsequent metastasis formation after local radiotherapy against a rat transplantable fibrosarcoma was studied. KMT-17 fibrosarcoma cells were transplanted into the hind leg of syngeneic WKA rats and the leg were irradiated with various doses of 60Co gamma-rays 5 days af... | ['Animals', 'Female', 'Fibrosarcoma', 'Neoplasm Metastasis', 'Neoplasm Transplantation', 'Radiotherapy Dosage', 'Rats', 'Rats, Inbred Strains', 'Spleen'] | 3,248,769 | [['B01.050'], ['C04.557.450.565.590.350', 'C04.557.450.795.350'], ['C04.697.650', 'C23.550.727.650'], ['E05.624'], ['E02.815.639'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A10.549.700', 'A15.382.520.604.700']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ALL-1 gene rearrangements in acute myeloid leukemia: association with M4-M5 French-American-British classification subtypes and young age. | We have analyzed by Southern blotting the ALL-1 (MLL, HRX, Hrtx 1) gene configuration in a series of 126 patients with acute myeloid leukemia (AML) representative of all ages and French-American-British Classification groups and correlated this genetic feature with clinical and biological features at diagnosis. ALL-1 g... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Child', 'Child, Preschool', 'DNA-Binding Proteins', 'Female', 'France', 'Gene Rearrangement', 'Histone-Lysine N-Methyltransferase', 'Humans', 'Immunophenotyping', 'Infant', 'Infant, Newborn', 'Leukemia, Monocytic, Acute', 'Leukemia, Myelomonocytic, Acute', 'Male', 'Middle... | 7,712,464 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['D12.776.260'], ['Z01.542.286'], ['G05.344'], ['D08.811.913.555.500.800.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.5... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Hepatic lesion caused by halogenated anesthetics]. | Two patients has been presented to whom general anaesthesia consecutive with halogenated anesthetics has been administrated. In one of the observations the first anaesthesia was administrated with enfluorane and halothane was for the others. The two patients inured with jaundice and in one of them accompanied with hepa... | ['Chemical and Drug Induced Liver Injury', 'Enflurane', 'Halothane', 'Humans', 'Liver', 'Male', 'Middle Aged', 'Necrosis'] | 7,185,232 | [['C06.552.100', 'C25.100.562', 'C25.723.260'], ['D02.355.601.400'], ['D02.455.526.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['M01.060.116.630'], ['C23.550.717']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Occupational health impacts of climate change: current and future ISO standards for the assessment of heat stress. | The current system of International Standards (ISO) is assessed to consider whether standards are fit for purpose for the future in the context of climate change. ISO 7243, ISO 7933 and ISO 9886 provide the current ISO system for the assessment of heat stress. These involve a simple monitoring index, an analytical appr... | ['Climate Change', 'Clothing', 'Environmental Monitoring', 'Ergonomics', 'Heat Stress Disorders', 'Humans', 'Meteorological Concepts', 'Monitoring, Physiologic', 'Occupational Diseases', 'Occupational Exposure'] | 23,411,759 | [['G16.500.175.374'], ['J01.637.215'], ['N06.850.460.350.080', 'N06.850.780.375'], ['F02.784.412', 'J01.293.556'], ['C26.522'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.750', 'N06.230.300'], ['E01.370.520'], ['C24'], ['N06.850.460.350.600']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A yeast chemical genetic screen identifies inhibitors of human telomerase. | Telomerase comprises a reverse transcriptase and an internal RNA template that maintains telomeres in many eukaryotes, and it is a well-validated cancer target. However, there is a dearth of small molecules with efficacy against human telomerase in vivo. We developed a surrogate yeast high-throughput assay to identify ... | ['Catalytic Domain', 'Drug Evaluation, Preclinical', 'Enzyme Inhibitors', 'HeLa Cells', 'High-Throughput Screening Assays', 'Humans', 'Phenotype', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Telomerase', 'Telomere-Binding Proteins'] | 23,521,791 | [['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.290.750', 'E05.337.550'], ['D27.505.519.389'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['E05.916.680'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.695'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.35... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pedigrees of infertile Chinese men with Y chromosome microdeletions derived from natural transmission and de novo mutation. | Y chromosome microdeletions can cause male infertility and are classified as natural transmission and de novo mutations. To examine the source of these deletions in Chinese men and to provide a theoretical and laboratory basis for genetic counseling, patients from Northeast China with primary male infertility (N = 22) ... | ['Asian Continental Ancestry Group', 'China', 'Chromosome Banding', 'Chromosome Deletion', 'Chromosomes, Human, Y', 'Gene Deletion', 'Humans', 'Infertility, Male', 'Karyotype', 'Karyotyping', 'Male', 'Pedigree', 'Sequence Analysis, DNA', 'Sequence Tagged Sites', 'Sex Chromosome Aberrations', 'Sex Chromosome Disorders o... | 25,867,339 | [['M01.686.508.200'], ['Z01.252.474.164'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Eosinophilia and the seroprevalence of schistosomiasis and strongyloidiasis in newly arrived pediatric refugees: an examination of Centers for Disease Control and Prevention screening guidelines. | The US Centers for Disease Control and Prevention has published refugee health guidelines that recommend examination of the absolute eosinophil count (AEC) to screen for asymptomatic schistosomiasis and strongyloidiasis. We examined the predictive validity of an AEC >400 cells/microL to identify refugees with serologic... | ['Adolescent', 'Africa', 'Asia, Southeastern', 'Centers for Disease Control and Prevention, U.S.', 'Child', 'Child, Preschool', 'Eosinophilia', 'Female', 'Humans', 'Infant', 'Male', 'Mass Screening', 'Refugees', 'Retrospective Studies', 'Schistosomiasis', 'Sensitivity and Specificity', 'Seroepidemiologic Studies', 'Str... | 20,400,098 | [['M01.060.057'], ['Z01.058'], ['Z01.252.145'], ['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['M01.060.406'], ['M01.060.406.448'], ['C15.378.553.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.... | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Body mass index as a predictor of cancer in men. | In this prospective study 8,006 Japanese men, age 45-68 years, were examined between 1965 and 1968. Their height and weight were measured and they were asked for their weight at age 25. After a surveillance period of almost 15 years, 646 incident cases of the following cancers were identified: 104 stomach, 101 colon, 1... | ['Adult', 'Age Factors', 'Aged', 'Body Height', 'Body Weight', 'Colonic Neoplasms', 'Humans', 'Japan', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasms', 'Prostatic Neoplasms', 'Stomach Neoplasms'] | 3,856,045 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C04.588.274.476.411.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Genetic variation in the HR region of the env gene of HIV: A perspective for resistance to HIV fusion inhibitors. | HIV fusion inhibitors may be classified into three groups. Peptides binding to HR1 include T1249, C30, and T20 (enfuvirtide). Peptides binding to HR2 include 5-helix. XTT formazan, NB-2, and NB-64 are nonpeptide fusion inhibitors. Genotypic testing for drug resistance is used more commonly than phenotypic testing becau... | ['Gene Products, env', 'Genetic Variation', 'Genotype', 'HIV', 'HIV Fusion Inhibitors', 'HIV Infections', 'Humans', 'Microbial Sensitivity Tests', 'Molecular Sequence Data', 'RNA, Viral', 'Sequence Analysis, DNA'] | 20,874,419 | [['D12.776.775.320', 'D12.776.964.775.325', 'D12.776.964.970.880.325'], ['G05.365'], ['G05.380'], ['B04.820.650.589.650.350'], ['D27.505.519.957.500', 'D27.505.954.122.388.077.088.209', 'D27.505.954.122.388.538.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Can we explain the allergenicity of peanuts on the basis of the three-dimensional structure of its allergens and use the information to devise means of eliminating peanut allergy? | Helical bundles are found in all the known structures of peanut allergens. The peptide fragments, which survive gastrointestinal digestion of the allergens and are absorbed intact, are hypothesized to reassociate and form stable helical bundles in the circulation, which could elicit a specific IgE response resulting in... | ['Allergens', 'Amino Acid Sequence', 'Arachis', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Molecular Structure', 'Peanut Hypersensitivity', 'Sequence Homology, Amino Acid'] | 22,910,770 | [['D23.050.063'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.401.077'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['C20.543.480.370.572.750'], ['G02.111.810.200', 'G05.810.200']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of a purified scorpion toxin (tityustoxin) on the isolated guinea pig heart. | To study the cardiac effects induced by purified scorpion toxin (tityustoxin, TsTX), without circulatory and respiratory influences, isolated guinea pig hearts were used. Single injections of 10, 20 or 30 micrograms TsTX induced positive inotropic and chronotropic effects in the majority of the experiments. The inotrop... | ['Animals', 'Coronary Circulation', 'Electrocardiography', 'Female', 'Guinea Pigs', 'Heart', 'Heart Rate', 'In Vitro Techniques', 'Male', 'Myocardial Contraction', 'Neurotoxins', 'Propranolol', 'Scorpion Venoms'] | 7,179,293 | [['B01.050'], ['G09.330.100.324'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.992.550'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E05.481'], ['G09.330.580', 'G11.427.494.570'], ['D27.888.569.504'], ['D02.033.100.624.698.711', 'D02.033.755.624.698.711', 'D02.092.063.624.698.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Repeated thyroid surgery. Indications and results]. | OBJECTIVES: To analyze the histology results and to assess operative risk of iterative operations for thyroid surgery.PATIENTS AND METHODS: A total of 249 re-operations were performed in 248 patients over a 6.5 year period. Two groups of patients were defined according to the indications for re-operation. Group 1: 80 p... | ['Goiter, Nodular', 'Humans', 'Reoperation', 'Thyroid Neoplasms', 'Thyroidectomy'] | 9,569,907 | [['C19.874.283.501'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.690'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788'], ['E04.270.856']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical impacts of tumor cell contamination of hematopoietic stem cell products in metastatic breast cancer patients undergoing autologous peripheral blood stem cell transplantation: multicenter trial. | To determine whether the tumor cell contamination of peripheral blood stem cells influences clinical impacts on high-dose chemotherapy in patients with metastatic breast cancer, we analyzed carcinoembryonic antigen (CEA) mRNA in the apheresis products by nested RT-PCR (reverse transcriptase-polymerase chain reaction). ... | ['Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Carcinoembryonic Antigen', 'Combined Modality Therapy', 'Cyclophosphamide', 'Disease-Free Survival', 'Doxorubicin', 'Epirubicin', 'Female', 'Fluorouracil', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Middle Aged', 'Multivariate A... | 11,306,743 | [['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E01.789.800.190', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Linking 'White oppression' and HIV/AIDS in American Indian etiology: conspiracy beliefs among MSMs and their peers. | This article presents the results of a pilot study on the use of conspiracy beliefs by American Indian (AI) men who have sex with men and their peers to explain the origins of HIV/AIDS. We found that one-third (N = 15) of the individuals surveyed believed that HIV/AIDS was intentionally created by "Whites, White Christ... | ['Adult', 'Anthropology, Cultural', 'Attitude to Health', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Indians, North American', 'Male', 'Middle Aged', 'Social Identification', 'Socioeconomic Factors', 'United States'] | 17,602,412 | [['M01.060.116'], ['I01.076.201'], ['F01.100.150', 'N05.300.150'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['M... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Interactions between the autonomic nervous system and tachycardias in man. | We have endeavoured to present an integrated and dynamic overview of the interaction between the autonomic nervous system and cardiac arrhythmias. Our purpose was not to be comprehensive, detailed, or all inclusive but to present a clinically relevant summary of some of the areas where autonomic tone may be pertinent. ... | ['Anti-Arrhythmia Agents', 'Atrial Fibrillation', 'Autonomic Nervous System', 'Blood Pressure', 'Diagnosis, Differential', 'Electrocardiography', 'Heart Conduction System', 'Heart Rate', 'Heart Ventricles', 'Humans', 'Myocardial Infarction', 'Reflex', 'Sympathetic Nervous System', 'Tachycardia', 'Tachycardia, Paroxysma... | 6,544,634 | [['D27.505.954.411.097'], ['C14.280.067.198', 'C23.550.073.198'], ['A08.800.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.171'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.409'], ['E01.370.600.875.500', 'G09.330.380.500'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outbreak of Mycoplasma pneumoniae-Associated Stevens-Johnson Syndrome. | BACKGROUND: Stevens-Johnson syndrome (SJS) is an uncommon, sporadic disease and outbreaks are rare. In November 2013, an outbreak of SJS was identified at Children's Hospital Colorado.METHODS: Outbreak cases were children aged 5-21 with a discharge diagnosis of SJS admitted from September 1 to November 30, 2013. Medica... | ['Adolescent', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Colorado', 'Disease Outbreaks', 'Female', 'Humans', 'Male', 'Pneumonia, Mycoplasma', 'Polymerase Chain Reaction', 'Retrospective Studies', 'Stevens-Johnson Syndrome', 'Young Adult'] | 26,216,320 | [['M01.060.057'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.567.875.760.210'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.610.610.760', 'C01.150.252.620.500', 'C01.748.610.540.545', 'C08.381.677... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments. | The ARF GTP binding proteins are believed to function as regulators of membrane traffic in the secretory pathway. While the ARF1 protein has been shown in vitro to mediate the membrane interaction of the cytosolic coat proteins coatomer (COP1) and gamma-adaptin with the Golgi complex, the functions of the other ARF pro... | ['ADP-Ribosylation Factor 1', 'ADP-Ribosylation Factors', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Compartmentation', 'Cell Membrane', 'Cells, Cultured', 'DNA Primers', 'GTP-Binding Proteins', 'Golgi Apparatus', 'Haplorhini', 'Humans', 'Molecular Sequence Data', 'Mutation', 'Sequence Alignment'] | 7,896,867 | [['D08.811.277.040.330.300.400.100.100', 'D12.644.360.525.100.100', 'D12.776.157.325.515.100.100', 'D12.776.476.525.100.100', 'D12.776.543.990.300.150'], ['D08.811.277.040.330.300.400.100', 'D12.644.360.525.100', 'D12.776.157.325.515.100', 'D12.776.476.525.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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